148:″(a) Identification. A sorbent hemoperfusion system is a prescription device that consists of an extracorporeal blood system similar to that identified in the hemodialysis system and accessories (876.5820) and a container filled with adsorbent material that removes a wide range of substances, both toxic and normal, from blood flowing through it. The adsorbent materials are usually activated-carbon or resins which may be coated or immobilized to prevent fine particles entering the patient's blood. The generic type of device may include lines and filters specifically designed to connect the device to the extracorporeal blood system. The device is used in the treatment of poisoning, drug overdose, hepatic coma, or metabolic disturbances.″
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Code of
Federal Regulations (CFR); Title 21, Volume 8; Revised as of April 1, 2014; CITE: 21CFR876.5870 See Related Information on Sorbent hemoperfusion system. in CDRH databases TITLE 21--FOOD AND DRUGS CHAPTER I--FOOD AND DRUG ADMINISTRATION DEPARTMENT OF HEALTH AND HUMAN SERVICES SUBCHAPTER
318:"Curso ENARM 2020 ®. | Guia ENARM Examen Nacional De Aspirantes A Residencias Medicas 2020 ENARM | Curso Enarm 2020 Totalmente Interactivo, ¡ACREDITACION GARANTIZADA! Incluye Material Didactico, Residencias Médicas, ENARM, Bancos de Preguntas y Seminarios, Envio Gratis"
226:, and some reduction in clotting factors, with recovery typically occurring in 1–2 days. Risk of bleeding is also higher because of the high heparin dose and reduction in platelets and clotting factors.
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During hemoperfusion, the blood passes through a column with absorptive properties aiming at removing specific toxic substances from the patient's blood. It especially targets small- to medium-sized
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Manual of
Clinical Dialysis, Second Edition, Ch. 16.2.3.2, pp.231-232 Springer, Suhail Ahmad, University of Washington, Scribner Kidney Center, Northwest Kidney Centers, Seattle, Washington, USA
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Manual of
Clinical Dialysis, Second Edition, Ch. 16.2.3, pp.229-232 Springer, Suhail Ahmad, University of Washington, Scribner Kidney Center, Northwest Kidney Centers, Seattle, Washington, USA
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Manual of
Clinical Dialysis, Second Edition, Ch. 16.2, pp. 229-232 Springer, Suhail Ahmad, University of Washington, Scribner Kidney Center, Northwest Kidney Centers, Seattle, Washington, USA
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Rahman MH, Haqqie SS, McGoldrick MD (2006). "Acute hemolysis with acute renal failure in a patient with valproic acid poisoning treated with charcoal hemoperfusion".
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88:(HDF), the blood travels from the patient into a machine, gets filtered, and then travels back into the patient, typically by venovenous access (out of a
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First introduced in the 1940s, hemoperfusion was refined during the 1950s through 1970s, and then introduced clinically for the treatment of
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H--MEDICAL DEVICES PART 876 -- GASTROENTEROLOGY-UROLOGY DEVICES Subpart F--Therapeutic
Devices Sec. 876.5870 Sorbent hemoperfusion system.
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205:- XAD series) are frequently more efficient at clearing lipid-soluble drugs than charcoal hemoperfusion.
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from the blood in emergency situations, removing waste products from the blood in patients with
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form of treatment because the blood is pumped through a device outside the patient's body.
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Hemoperfusion is also used in the treatment of specific intoxications, such as
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Despite its availability, this technique is only infrequently utilized as a
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In hemoperfusion, the blood perfuses a filter composed of
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that tend to be more difficult to remove by conventional
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process used to remove toxic substances from a patient's
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extracorporeally (that is, outside the body) to remove a
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in the 1970s and 1980s. It is sometimes used to treat
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Charcoal hemoperfusion, which has been used to treat
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145:(FDA) defines sorbent hemoperfusion as follows:
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