1287:, lack of speech, and excessively happy demeanor. Angelman syndrome results from a loss of gene activity in a specific part of chromosome 15, the 15q11-q13 region. This region contains a gene called UBE3A that, when mutated or absent, likely causes the characteristic features of this condition. People normally have two copies of the UBE3A gene, one from each parent. Both copies of this gene are active in many of the body's tissues. In the brain, however, only the copy inherited from a person's mother (the maternal copy) is active. If the maternal copy is lost because of a chromosomal change or a gene mutation, a person will have no working copies of the UBE3A gene in the brain.
47:
1451:
1471:
2883:
2583:
1362:) can affect growth and development. The patient possesses an "extra" or "marker" chromosome. This small extra chromosome is made up of genetic material from chromosome 15 that has been abnormally duplicated (copied) and attached end-to-end. In some cases, the extra chromosome is very small and has no effect on a person's health. A larger isodicentric chromosome 15 can result in weak muscle tone (hypotonia), intellectual disability, seizures, and behavioral problems. Signs and symptoms of
2884:"Search results – 15[CHR] AND "Homo sapiens"[Organism] AND ( ("genetype miscrna"[Properties] OR "genetype ncrna"[Properties] OR "genetype rrna"[Properties] OR "genetype trna"[Properties] OR "genetype scrna"[Properties] OR "genetype snrna"[Properties] OR "genetype snorna"[Properties]) NOT "genetype protein coding"[Properties] AND alive[prop]) – Gene"
1302:
About 10% of
Angelman syndrome cases are caused by a mutation in the UBE3A gene, and another 3% result from a defect in the DNA region that controls the activation of the UBE3A gene and other genes on the maternal copy of chromosome 15. In a small percentage of cases, Angelman syndrome may be caused
1298:
In 3% to 7% of cases, Angelman syndrome occurs when a person has two copies of the paternal chromosome 15 instead of one copy from each parent. This phenomenon is called paternal uniparental disomy (UPD). People with paternal UPD for chromosome 15 have two copies of the UBE3A gene, but they are both
2955:
The program...recounts how one scientist determined how the deletion of a key sequence of DNA on human chromosome 15 could lead to two different syndromes depending on whether the deletion originated from the mother or the father explains that this was the first human evidence that something other
1339:
In about 25% of cases, a person with Prader–Willi syndrome has two maternal copies of chromosome 15 in each cell instead of one copy from each parent. This phenomenon is called maternal uniparental disomy. Because some genes are normally active only on the paternal copy of this chromosome, a person
1332:. Prader-Willi syndrome is caused by the loss of active genes in a specific part of chromosome 15, the 15q11-q13 region. People normally have two copies of this chromosome in each cell, one copy from each parent. Prader–Willi syndrome occurs when the paternal copy is partly or entirely missing.
1335:
In about 70% of cases, Prader–Willi syndrome occurs when the 15q11-q13 region of the paternal chromosome 15 is deleted. The genes in this region are normally active on the paternal copy of the chromosome and are inactive on the maternal copy. Therefore, a person with a deletion in the paternal
1343:
In a small percentage of cases, Prader–Willi syndrome is not caused by a chromosomal rearrangement called a translocation. Rarely, the condition is caused by an abnormality in the DNA region that controls the activity of genes on the paternal chromosome 15. Because patients almost always have
1374:
Other changes in the number or structure of chromosome 15 can cause developmental delays, delayed growth and development, hypotonia, and characteristic facial features. These changes include an extra copy of part of chromosome 15 in each cell (partial trisomy 15) or a missing segment of the
1476:
G-banding patterns of human chromosome 15 in three different resolutions (400, 550 and 850). Band length in this diagram is based on the ideograms from ISCN (2013). This type of ideogram represents actual relative band length observed under a microscope at the different moments during the
298:. Chromosome 15 is an acrocentric chromosome, with a very small short arm (the "p" arm, for "petite"), which contains few protein coding genes among its 19 million base pairs. It has a larger long arm (the "q" arm) that is gene rich, spanning about 83 million base pairs.
2858:
1294:
gene. Because the copy of the UBE3A gene inherited from a person's father (the paternal copy) is normally inactive in the brain, a deletion in the maternal chromosome 15 results in no active copies of the UBE3A gene in the brain.
2908:
2654:
133:
29:
3381:
Borgatti R, Piccinelli P, Passoni D, Dalpra L, Miozzo M, Micheli R, Gagliardi C, Balottin U (2001). "Relationship between clinical and genetic features in "inverted duplicated chromosome 15" patients".
1456:
G-banding ideogram of human chromosome 15 in resolution 850 bphs. Band length in this diagram is proportional to base-pair length. This type of ideogram is generally used in genome browsers (e.g.
1290:
In most cases (about 70%), people with
Angelman syndrome have a deletion in the maternal copy of chromosome 15. This chromosomal change deletes the region of chromosome 15 that includes the
1413:
3565:"Identification of novel imprinted transcripts in the Prader-Willi syndrome and Angelman syndrome deletion region: further evidence for regional imprinting control"
1261:) involve a loss of gene activity in the same part of chromosome 15, the 15q11.2-q13.1 region. This discovery provided the first evidence in humans that something
1303:
by a chromosomal rearrangement called a translocation or by a mutation in a gene other than UBE3A. These genetic changes can abnormally inactivate the UBE3A gene.
4486:
3192:
These values (ISCN start/stop) are based on the length of bands/ideograms from the ISCN book, An
International System for Human Cytogenetic Nomenclature (2013).
3637:"Partial duplication of the long arm of chromosome 15: confirmation of a causative role in craniosynostosis and definition of a 15q25-qter trisomy syndrome"
1366:(a developmental disorder that affects communication and social interaction) have also been associated with the presence of an isodicentric chromosome 15.
2859:"Search results – 15[CHR] AND "Homo sapiens"[Organism] AND ("genetype protein coding"[Properties] AND alive[prop]) – Gene"
309:
is found on chromosome 15, as well as the FBN1 gene, coding for both fibrillin-1 (a protein critical to the proper functioning of connective tissue), and
342:) takes an extremely conservative strategy. So CCDS's gene number prediction represents a lower bound on the total number of human protein-coding genes.
1375:
chromosome in each cell (partial monosomy 15). In some cases, several of the chromosome's DNA building blocks (nucleotides) are deleted or duplicated.
2909:"Search results – 15[CHR] AND "Homo sapiens"[Organism] AND ("genetype pseudo"[Properties] AND alive[prop]) – Gene"
3009:
1056:
635:
3987:
458:
205:
164:
2655:"Search results – 15[CHR] AND "Homo sapiens"[Organism] AND ("has ccds"[Properties] AND alive[prop]) – Gene"
1306:
Angelman syndrome can be hereditary, as evidenced by one case where a patient became pregnant with a daughter who also had the condition.
3619:
529:
3653:
3636:
914:
210:
4384:
629:
1095:: the gene responsible for at least 1/3 of the skin color differences between races, expressed in the brain and the nervous system
4439:
4434:
2779:
491:
The following is a partial list of genes on human chromosome 15. For complete list, see the link in the infobox on the right.
4512:
4476:
4117:
3741:
3136:
3099:
2694:
745:
486:
3606:
Rineer S, Finucane B, Simon EW (1998). "Autistic symptoms among children and young adults with isodicentric chromosome 15".
3467:
4481:
1166:
866:
326:
The following are some of the gene count estimates of human chromosome 15. Because researchers use different approaches to
4239:
963:: promyelocytic leukemia protein (involved in t(15,17) with RARalpha, predominant cause of acute promyelocytic leukemia.
3702:
1192:
3980:
3413:"Behavioral differences among subjects with Prader-Willi syndrome and type I or type II deletion and maternal disomy"
2626:
2604:
2597:
4256:
936:
561:
395:
140:
3679:
2938:
579:
416:
181:
1359:
3115:
Sethakulvichai, W.; Manitpornsut, S.; Wiboonrat, M.; Lilakiatsakun, W.; Assawamakin, A.; Tongsima, S. (2012).
28:
4102:
3454:
Cassidy SB, Dykens E, Williams CA (2000). "Prader-Willi and
Angelman syndromes: sister imprinted disorders".
313:(a small protein produced from part of the transcribed FBN1 gene mRNA), which is involved in fat metabolism.
3075:
3062:
2715:
4507:
3973:
3923:
2808:
169:
1358:
A specific chromosomal change called an isodicentric chromosome 15 (IDIC15) (also known by a number of
948:
3017:
222:
198:
46:
4249:
3734:
2943:
1315:
1258:
701:
3534:
Gilbert F (1999). "Disease genes and chromosomes: disease maps of the human genome. Chromosome 15".
4303:
4087:
3954:
2591:
1397:
3087:
2933:
804:
La-related protein 6 also known as acheron or La ribonucleoprotein domain family member 6 (LARP6),
3297:"Microarray analysis of gene/transcript expression in Prader-Willi syndrome: deletion versus UPD"
1236:
302:
4209:
4182:
2608:
1253:
The following conditions are caused by mutations in chromosome 15. Two of the conditions (
1201:: ubiquitin protein ligase E3A (human papilloma virus E6-associated protein, Angelman syndrome)
942:
186:
242:
4244:
4142:
3340:"Microarray analysis of gene/transcript expression in Angelman syndrome: deletion versus UPD"
2684:
1419:
1408:
729:
374:
339:
286:. People normally have two copies of this chromosome. Chromosome 15 spans about 99.7 million
261:
229:
128:
91:
4464:
4389:
4374:
4204:
4152:
4127:
4067:
3942:
3727:
1429:
351:
306:
3038:
8:
4132:
3949:
1470:
1461:
1392:
1230:
217:
69:
3121:
2012 Ninth
International Conference on Computer Science and Software Engineering (JCSSE)
1450:
3589:
3564:
3517:
3492:
3479:
3437:
3412:
3364:
3339:
3321:
3296:
3278:
3253:
3142:
2756:
2729:
518:: a human-specific gene encoding the Rho GTPase activating protein 11B, that amplifies
3395:
4194:
4106:
3917:
3658:
3623:
3594:
3551:
3522:
3471:
3442:
3399:
3369:
3326:
3283:
3132:
3116:
3095:
2991:
2986:
2969:
2761:
2690:
1340:
with two maternal copies of chromosome 15 will have no active copies of these genes.
1278:
1254:
327:
3483:
3146:
2787:
145:
4283:
4162:
3648:
3615:
3584:
3576:
3543:
3512:
3504:
3463:
3432:
3424:
3391:
3359:
3351:
3316:
3308:
3273:
3265:
3177:
3124:
2981:
2751:
2741:
1210:
114:
1283:
The main characteristics of
Angelman syndrome are severe intellectual disability,
4276:
4097:
4045:
3089:
1403:
1363:
1353:
1266:
679:
519:
335:
331:
109:
82:
3355:
3114:
338:). Among various projects, the collaborative consensus coding sequence project (
4167:
4091:
3193:
3128:
1382:
954:
356:
295:
3269:
3254:"Prader-Willi syndrome: clinical genetics, cytogenetics and molecular biology"
4501:
4147:
3880:
3875:
3870:
3865:
3860:
3855:
3850:
3840:
3835:
3830:
3825:
3820:
2746:
1387:
1023:
860:
3965:
3620:
10.1002/(SICI)1096-8628(19980907)81:5<428::AID-AJMG12>3.0.CO;2-E
3547:
3091:
ISCN 2013: An
International System for Human Cytogenetic Nomenclature (2013)
2833:
1378:
The following diseases are some of those related to genes on chromosome 15:
157:
4122:
3996:
3937:
3903:
3898:
3815:
3810:
3805:
3800:
3795:
3790:
3785:
3780:
3775:
3750:
3662:
3654:
10.1002/(SICI)1096-8628(19991222)87:5<391::AID-AJMG4>3.0.CO;2-O
3598:
3555:
3526:
3475:
3446:
3428:
3403:
3373:
3330:
3287:
3088:
International
Standing Committee on Human Cytogenetic Nomenclature (2013).
2995:
2765:
1344:
difficulty reproducing, Prader–Willi syndrome is generally not hereditary.
1325:
872:
265:
246:
3627:
1069:: S-phase CyclinA Associated Protein residing in the Endoplasmic Reticulum
4341:
4336:
4199:
4177:
4172:
4040:
3758:
3312:
1424:
1262:
689:
597:
3508:
4361:
4351:
4346:
4331:
4271:
4261:
4137:
4111:
4062:
4052:
4000:
3687:
3228:
3221:
3213:
1321:
960:
775:
657:
610:
ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial
585:
361:
279:
3338:
Bittel DC, Kibiryeva N, Talebizadeh Z, Driscoll DJ, Butler MG (2005).
2834:"Human chromosome 15: entries, gene names and cross-references to MIM"
1324:(extreme, insatiable appetite), mild to moderate developmental delay,
4313:
4057:
4035:
4016:
3411:
Butler MG, Bittel DC, Kibiryeva N, Talebizadeh Z, Thompson T (2004).
3209:
2730:"Between a chicken and a grape: estimating the number of human genes"
1489:
1329:
1204:
817:
523:
515:
287:
54:
34:
4299:
4083:
3890:
3767:
3580:
3468:
10.1002/1096-8628(200022)97:2<136::AID-AJMG5>3.0.CO;2-V
1299:
inherited from the father and are therefore inactive in the brain.
898:
844:
791:
567:
551:
310:
102:
3337:
4469:
4323:
4234:
4229:
3493:"Angelman syndrome: a review of the clinical and genetic aspects"
3117:"Estimation of band level resolutions of human chromosome images"
1478:
1457:
1240:
1224:
1214:
1186:
1176:
1160:
1138:
1128:
1112:
1102:
1092:
1086:
1060:
1050:
1040:
1018:
1002:
986:
972:
930:
908:
892:
882:
876:
854:
841:
831:
821:
801:
785:
781:
759:
749:
739:
719:
713:
683:
667:
663:
651:
638:: encoding protein Cytochrome p450 family 19 subfamily a member 1
617:
555:
539:
535:
437:
255:
152:
3410:
3294:
1430:
Autosomal
Dominant Compelling Helio-Ophthalmic Outburst syndrome
911:
Non-imprinted in Prader-Willi/Angelman syndrome region protein 2
4379:
4266:
4030:
4026:
4021:
3719:
3380:
1284:
1172:
1150:
1098:
1076:
1066:
1046:
1036:
1030:
976:
923:: oculocutaneous albinism II (pink-eye dilution homolog, mouse)
888:
827:
811:
769:
735:
613:
607:
522:, controls neural progenitor proliferation, and contributes to
506:
502:
236:
193:
3108:
3076:
Ideogram data for Homo sapience (550 bphs, Assembly GRCh38.p3)
3063:
Ideogram data for Homo sapience (400 bphs, Assembly GRCh38.p3)
2956:
than genes themselves could determine how genes are expressed.
2716:
Ideogram data for Homo sapience (850 bphs, Assembly GRCh38.p3)
532:: encoding protein Actin related protein 2/3 complex inhibitor
4444:
4429:
4424:
4419:
4414:
4409:
4404:
4399:
4394:
4369:
4307:
3220:: Region which is negatively stained by G banding, generally
1291:
1220:
1198:
1182:
1124:
1082:
1072:
998:
992:
982:
966:
926:
917:: encoding protein Nucleolar and spindle associated protein 1
904:
850:
837:
807:
797:
765:
695:
641:
623:
591:
573:
496:
283:
3634:
1156:
1144:
1134:
1118:
1108:
1014:
1008:
920:
755:
725:
707:
673:
647:
632:: encoding protein Cervical cancer-associated transcript 37
603:
545:
3677:
3295:
Bittel DC, Kibiryeva N, Talebizadeh Z, Butler MG (2003).
3039:"Photic Sneeze Reflex | AncestryDNA® Traits Learning Hub"
2970:"Transmission of Angelman syndrome by an affected mother"
1021:
Rtf1, Paf1/RNA polymerase II complex component, homolog (
294:) and represents between 3% and 3.5% of the total DNA in
291:
1336:
chromosome 15 will have no active genes in this region.
626:: Cytoplasmic polyladenylation element binding protein 1
4487:
International System for Human
Cytogenetic Nomenclature
2682:
1169:: encoding protein Transmembrane 6 superfamily member 1
995:: RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)
969:: encoding protein POTE ankyrin domain family, member B
869:: encoding protein Multiple c2 domains, transmembrane 2
570:: encoding protein Chromosome 15 Open Reading Frame 54
334:
on each chromosome varies (for technical details, see
3453:
2727:
1195:: encoding protein Ubiquitin conjugating enzyme e2 q2
660:: fumarylacetoacetate hydrolase (fumarylacetoacetase)
1153:: location 3p24.2-p25 due to a inactivation mutation
576:: Calpain 3 (limb-girdle muscular dystrophy type 2A)
3635:Zollino M, Tiziano F, Di Stefano C, Neri G (1999).
3605:
1320:The main characteristics of this condition include
1033:: encoding protein Replication termination factor 2
564:: encoding protein Uncharacterized protein C15orf32
3707:Human Genome Project Information Archive 1990–2003
3176:For cytogenetic banding nomenclature, see article
2809:"Chromosome 15: Chromosome summary – Homo sapiens"
698:: GTP cyclohydrolase 1 feedback regulatory protein
582:: encoding protein Cugbp elav-like family member 6
3490:
2801:
979:Protein tyrosine phosphatase-like protein PTPLAD1
762:U3 small nucleolar ribonucleoprotein protein IMP3
548:: encoding protein Beta-2-microglobulin regulator
4499:
3081:
3078:. Last update 2015-08-11. Retrieved 2017-04-26.
3065:. Last update 2014-03-04. Retrieved 2017-04-26.
2718:. Last update 2014-06-03. Retrieved 2017-04-26.
2676:
1369:
1053:Secretory carrier-associated membrane protein 5
1043:Secretory carrier-associated membrane protein 2
716:: encoding protein Golgin subfamily A member 8H
509:Acyl-CoA Synthetase, Bubblegum Family, member 1
2967:
2780:"Statistics & Downloads for chromosome 15"
1492:of human chromosome 15 in resolution 850 bphs
1063:Schizophrenia disorder 10 (periodic catatonia)
3995:
3981:
3735:
2876:
1347:
1147:: encoding protein Testis-expressed protein 9
957:: encoding protein Phospholipase A2 group IVE
951:: encoding protein Phospholipase A2 group IVD
939:: encoding protein PIF1 5'-to-3' DNA helicase
863:: microcephaly, primary autosomal recessive 4
3251:
3094:. Karger Medical and Scientific Publishers.
704:: encoding protein Glaucoma 1, open angle, i
2901:
2772:
2721:
1005:Regulator of microtubule dynamics protein 3
3988:
3974:
3742:
3728:
3562:
2851:
2683:Tom Strachan; Andrew Read (2 April 2010).
1443:G-banding ideograms of human chromosome 15
1105:snRNA-activating protein complex subunit 5
824:Long intergenic non-protein coding RNA 926
654:Elongation factor RNA polymerase II-like 3
558:Probable ribosome biogenesis protein RLP24
499:: alpha- and gamma-adaptin binding protein
45:
27:
3652:
3588:
3533:
3516:
3436:
3363:
3320:
3277:
2985:
2755:
2745:
2710:
2708:
2706:
2627:Learn how and when to remove this message
1248:
945:: encoding protein Pigb opposite strand 1
692:: Glycine aminotransferase, mitochondrial
3208:: Region which is positively stained by
2590:This article includes a list of general
1328:resulting in delayed to no puberty, and
1309:
1179:Transmembrane and coiled-coil domains 5A
3188:
3186:
3068:
3055:
1189:Transmembrane p24 trafficking protein 3
1011:: encoding RNA, ribosomal 45S cluster 3
728:: hexosaminidase A (alpha polypeptide)(
39:One is from mother, one is from father.
4500:
2826:
2703:
2649:
2647:
1233:: encoding protein Wd repeat domain 76
4477:List of organisms by chromosome count
3969:
3723:
778:: isovaleryl Coenzyme A dehydrogenase
752:Insulin dependent diabetes mellitus 3
487:Category:Genes on human chromosome 15
3183:
2576:
1272:
814:Leucine carboxyl methyltransferase 2
3010:"What is Dup15q Syndrome? – Dup15q"
2644:
1435:
901:: encoding protein MIR9-3 host gene
857:Microfibrillar-associated protein 1
13:
2596:it lacks sufficient corresponding
321:
14:
4524:
3671:
772:Inositol-trisphosphate 3-kinase A
3749:
3491:Clayton-Smith J, Laan L (2003).
3074:Genome Decoration Page, NCBI.
2987:10.1097/00125817-199909000-00004
2784:HUGO Gene Nomenclature Committee
2714:Genome Decoration Page, NCBI.
2581:
1469:
1449:
885:: encoding protein MicroRNA 1282
620:COMM domain-containing protein 4
594:: Chondroitin sulfate synthase 1
542:cAMP-regulated phosphoprotein 19
4098:Macrochromosome/Microchromosome
3678:National Institutes of Health.
3199:
3170:
3153:
3031:
3002:
2961:
2939:Ghost in Your Genes (season 35)
2926:
2689:. Garland Science. p. 45.
933:Programmed cell death protein 7
742:High mobility group protein 20A
676:: fibrillin 1 (Marfan syndrome)
33:Human chromosome 15 pair after
3061:Genome Decoration Page, NCBI.
2728:Pertea M, Salzberg SL (2010).
989:Pygopus homolog 1 (Drosophila)
588:: Calcium binding protein P22\
83:
1:
3396:10.1016/S0887-8994(00)00244-7
3252:Bittel DC, Butler MG (2005).
2968:Lossie A, Driscoll D (1999).
2572:
4513:Genes on human chromosome 15
2786:. 2017-05-12. Archived from
1370:Other chromosomal conditions
1163:Transmembrane channel like 3
480:
7:
3356:10.1016/j.ygeno.2004.10.010
1079:Sentrin-specific protease 8
847:posterior 1 homolog (mouse)
794:: encoding protein Kiaa1024
710:: D-glucuronyl C5-epimerase
512:ADH1: alcohol dehydrogenase
10:
4529:
4138:Dinoflagellate chromosomes
3129:10.1109/JCSSE.2012.6261965
1351:
1348:Isodicentric chromosome 15
1313:
1276:
484:
290:(the building material of
278:is one of the 23 pairs of
4482:List of sequenced genomes
4457:
4360:
4322:
4292:
4250:Chromosomal translocation
4220:
4123:A chromosome/B chromosome
4114:(or accessory chromosome)
4076:
4007:
3930:
3916:
3889:
3766:
3757:
3563:Lee S, Wevrick R (2000).
3270:10.1017/S1462399405009531
1227:hVam6p/Vps39-like protein
330:their predictions of the
254:
235:
228:
216:
204:
192:
180:
175:
163:
151:
139:
127:
122:
108:
98:
81:
67:
62:
44:
26:
21:
4304:Telomere-binding protein
4118:Supernumerary chromosome
2747:10.1186/gb-2010-11-5-206
2686:Human Molecular Genetics
1265:could determine how the
1131:Zinc finger protein 280D
1089:Small EDRK-rich factor 2
316:
3924:Human mitochondrial DNA
3684:Genetics Home Reference
3548:10.1089/109065799316653
2611:more precise citations.
1243:Zinc finger protein 592
303:human leukocyte antigen
4240:Structural alterations
3429:10.1542/peds.113.3.565
2661:. CCDS Release 20 for
1249:Chromosomal conditions
4257:Numerical alterations
4245:Chromosomal inversion
4143:Homologous chromosome
2639:Specific references:
1409:Nonsyndromic deafness
1400:, type 3 (SMAD3 gene)
1316:Prader–Willi syndrome
1310:Prader–Willi syndrome
1259:Prader–Willi syndrome
4465:Extrachromosomal DNA
4153:Satellite chromosome
4128:Lampbrush chromosome
4068:Nuclear organization
3943:Human Genome Project
3918:Mitochondrial genome
3313:10.1136/jmg.40.8.568
3246:General references:
3123:. pp. 276–282.
1414:Schaaf–Yang syndrome
357:Non-coding RNA genes
352:Protein-coding genes
176:External map viewers
4508:Chromosomes (human)
4158:Centromere position
4133:Polytene chromosome
4103:Circular chromosome
3950:List of human genes
3509:10.1136/jmg.40.2.87
3423:(3 Pt 1): 565–573.
3235:: Variable region;
1493:
1462:UCSC Genome Browser
1393:Isovaleric acidemia
1267:genes are expressed
834:LDLR chaperone MESD
600:: CDC like kinase 3
123:Complete gene lists
110:Centromere position
3258:Expert Rev Mol Med
2946:. October 16, 2007
2813:Ensembl Release 88
1488:
230:Full DNA sequences
51:Chromosome 15 pair
4495:
4494:
4453:
4452:
4190:Centromere number
4107:Linear chromosome
3963:
3962:
3955:Human archaeology
3912:
3911:
3690:on August 3, 2004
3138:978-1-4673-1921-8
3101:978-3-318-02253-7
2934:"Teacher's Guide"
2696:978-1-136-84407-2
2637:
2636:
2629:
2570:
2569:
1420:Tay–Sachs disease
1279:Angelman syndrome
1273:Angelman syndrome
1255:Angelman syndrome
730:Tay–Sachs disease
520:basal progenitors
478:
477:
328:genome annotation
273:
272:
4520:
4320:
4319:
4284:Polyploidization
4112:Extra chromosome
4027:Genetic material
3990:
3983:
3976:
3967:
3966:
3764:
3763:
3744:
3737:
3730:
3721:
3720:
3716:
3714:
3713:
3698:
3696:
3695:
3686:. Archived from
3666:
3656:
3631:
3602:
3592:
3559:
3530:
3520:
3487:
3450:
3440:
3407:
3377:
3367:
3334:
3324:
3291:
3281:
3240:
3203:
3197:
3190:
3181:
3174:
3168:
3157:
3151:
3150:
3112:
3106:
3105:
3085:
3079:
3072:
3066:
3059:
3053:
3052:
3050:
3049:
3043:www.ancestry.com
3035:
3029:
3028:
3026:
3025:
3016:. Archived from
3006:
3000:
2999:
2989:
2965:
2959:
2958:
2952:
2951:
2944:Nova (TV series)
2930:
2924:
2923:
2921:
2920:
2905:
2899:
2898:
2896:
2895:
2880:
2874:
2873:
2871:
2870:
2855:
2849:
2848:
2846:
2845:
2830:
2824:
2823:
2821:
2820:
2805:
2799:
2798:
2796:
2795:
2776:
2770:
2769:
2759:
2749:
2725:
2719:
2712:
2701:
2700:
2680:
2674:
2673:
2671:
2670:
2651:
2632:
2625:
2621:
2618:
2612:
2607:this article by
2598:inline citations
2585:
2584:
2577:
2561:
2556:
2528:
2523:
2496:
2491:
2463:
2458:
2431:
2426:
2398:
2393:
2366:
2361:
2333:
2328:
2301:
2296:
2268:
2263:
2236:
2231:
2203:
2198:
2171:
2166:
2138:
2133:
2106:
2101:
2073:
2068:
2041:
2036:
2008:
2003:
1976:
1971:
1943:
1938:
1911:
1906:
1878:
1873:
1846:
1841:
1813:
1808:
1781:
1776:
1748:
1743:
1716:
1711:
1684:
1679:
1652:
1647:
1620:
1615:
1588:
1583:
1556:
1551:
1494:
1487:
1473:
1453:
1436:Cytogenetic band
1217:Unc-13 homolog C
345:
344:
307:β2-microglobulin
269:
250:
85:
49:
31:
19:
18:
16:Human chromosome
4528:
4527:
4523:
4522:
4521:
4519:
4518:
4517:
4498:
4497:
4496:
4491:
4449:
4356:
4318:
4288:
4277:Paleopolyploidy
4222:
4216:
4072:
4046:Heterochromatin
4009:
4003:
3994:
3964:
3959:
3926:
3908:
3885:
3753:
3748:
3711:
3709:
3703:"Chromosome 15"
3701:
3693:
3691:
3680:"Chromosome 15"
3674:
3669:
3244:
3243:
3224:and gene rich;
3216:and gene poor;
3204:
3200:
3191:
3184:
3175:
3171:
3163:": Short arm; "
3158:
3154:
3139:
3113:
3109:
3102:
3086:
3082:
3073:
3069:
3060:
3056:
3047:
3045:
3037:
3036:
3032:
3023:
3021:
3008:
3007:
3003:
2966:
2962:
2949:
2947:
2932:
2931:
2927:
2918:
2916:
2907:
2906:
2902:
2893:
2891:
2882:
2881:
2877:
2868:
2866:
2857:
2856:
2852:
2843:
2841:
2832:
2831:
2827:
2818:
2816:
2807:
2806:
2802:
2793:
2791:
2778:
2777:
2773:
2726:
2722:
2713:
2704:
2697:
2681:
2677:
2668:
2666:
2653:
2652:
2645:
2633:
2622:
2616:
2613:
2603:Please help to
2602:
2586:
2582:
2575:
2559:
2554:
2526:
2521:
2494:
2489:
2461:
2456:
2429:
2424:
2396:
2391:
2364:
2359:
2331:
2326:
2299:
2294:
2266:
2261:
2234:
2229:
2201:
2196:
2169:
2164:
2136:
2131:
2104:
2099:
2071:
2066:
2039:
2034:
2006:
2001:
1974:
1969:
1941:
1936:
1909:
1904:
1876:
1871:
1844:
1839:
1811:
1806:
1779:
1774:
1746:
1741:
1714:
1709:
1682:
1677:
1650:
1645:
1618:
1613:
1586:
1581:
1554:
1549:
1522:
1517:
1512:
1507:
1486:
1485:
1484:
1483:
1482:
1479:mitotic process
1474:
1466:
1465:
1454:
1445:
1444:
1438:
1404:Marfan syndrome
1372:
1356:
1354:Isodicentric 15
1350:
1318:
1312:
1281:
1275:
1251:
1246:
686:Forkhead box B1
670:Protein FAM214A
489:
483:
336:gene prediction
332:number of genes
324:
322:Number of genes
319:
260:
241:
117:
76:
58:
52:
40:
38:
17:
12:
11:
5:
4526:
4516:
4515:
4510:
4493:
4492:
4490:
4489:
4484:
4479:
4474:
4473:
4472:
4461:
4459:
4455:
4454:
4451:
4450:
4448:
4447:
4442:
4437:
4432:
4427:
4422:
4417:
4412:
4407:
4402:
4397:
4392:
4387:
4382:
4377:
4372:
4366:
4364:
4358:
4357:
4355:
4354:
4349:
4344:
4339:
4334:
4328:
4326:
4317:
4316:
4311:
4296:
4294:
4290:
4289:
4287:
4286:
4281:
4280:
4279:
4274:
4269:
4264:
4254:
4253:
4252:
4247:
4237:
4232:
4226:
4224:
4218:
4217:
4215:
4214:
4213:
4212:
4207:
4202:
4197:
4187:
4186:
4185:
4180:
4175:
4170:
4168:Submetacentric
4165:
4155:
4150:
4145:
4140:
4135:
4130:
4125:
4120:
4115:
4109:
4100:
4095:
4094:or heterosome)
4088:Sex chromosome
4080:
4078:
4074:
4073:
4071:
4070:
4065:
4060:
4055:
4050:
4049:
4048:
4043:
4033:
4024:
4019:
4013:
4011:
4005:
4004:
3993:
3992:
3985:
3978:
3970:
3961:
3960:
3958:
3957:
3952:
3947:
3946:
3945:
3934:
3932:
3931:Related topics
3928:
3927:
3922:
3920:
3914:
3913:
3910:
3909:
3907:
3906:
3901:
3895:
3893:
3891:Sex chromosome
3887:
3886:
3884:
3883:
3878:
3873:
3868:
3863:
3858:
3853:
3848:
3843:
3838:
3833:
3828:
3823:
3818:
3813:
3808:
3803:
3798:
3793:
3788:
3783:
3778:
3772:
3770:
3761:
3759:Nuclear genome
3755:
3754:
3747:
3746:
3739:
3732:
3724:
3718:
3717:
3699:
3673:
3672:External links
3670:
3668:
3667:
3647:(5): 391–394.
3641:Am J Med Genet
3632:
3614:(5): 428–433.
3608:Am J Med Genet
3603:
3581:10.1086/302817
3575:(3): 848–858.
3569:Am J Hum Genet
3560:
3542:(3): 309–322.
3531:
3488:
3462:(2): 136–146.
3456:Am J Med Genet
3451:
3408:
3390:(2): 111–116.
3384:Pediatr Neurol
3378:
3335:
3307:(8): 568–574.
3292:
3248:
3242:
3241:
3198:
3194:Arbitrary unit
3182:
3169:
3152:
3137:
3107:
3100:
3080:
3067:
3054:
3030:
3014:www.dup15q.org
3001:
2960:
2925:
2900:
2875:
2850:
2825:
2800:
2771:
2720:
2702:
2695:
2675:
2642:
2641:
2635:
2634:
2617:September 2009
2589:
2587:
2580:
2574:
2571:
2568:
2567:
2565:
2562:
2557:
2552:
2549:
2546:
2543:
2540:
2536:
2535:
2532:
2529:
2524:
2519:
2516:
2513:
2510:
2507:
2503:
2502:
2500:
2497:
2492:
2487:
2484:
2481:
2478:
2475:
2471:
2470:
2467:
2464:
2459:
2454:
2451:
2448:
2445:
2442:
2438:
2437:
2435:
2432:
2427:
2422:
2419:
2416:
2413:
2410:
2406:
2405:
2402:
2399:
2394:
2389:
2386:
2383:
2380:
2377:
2373:
2372:
2370:
2367:
2362:
2357:
2354:
2351:
2348:
2345:
2341:
2340:
2337:
2334:
2329:
2324:
2321:
2318:
2315:
2312:
2308:
2307:
2305:
2302:
2297:
2292:
2289:
2286:
2283:
2280:
2276:
2275:
2272:
2269:
2264:
2259:
2256:
2253:
2250:
2247:
2243:
2242:
2240:
2237:
2232:
2227:
2224:
2221:
2218:
2215:
2211:
2210:
2207:
2204:
2199:
2194:
2191:
2188:
2185:
2182:
2178:
2177:
2175:
2172:
2167:
2162:
2159:
2156:
2153:
2150:
2146:
2145:
2142:
2139:
2134:
2129:
2126:
2123:
2120:
2117:
2113:
2112:
2110:
2107:
2102:
2097:
2094:
2091:
2088:
2085:
2081:
2080:
2077:
2074:
2069:
2064:
2061:
2058:
2055:
2052:
2048:
2047:
2045:
2042:
2037:
2032:
2029:
2026:
2023:
2020:
2016:
2015:
2012:
2009:
2004:
1999:
1996:
1993:
1990:
1987:
1983:
1982:
1980:
1977:
1972:
1967:
1964:
1961:
1958:
1955:
1951:
1950:
1947:
1944:
1939:
1934:
1931:
1928:
1925:
1922:
1918:
1917:
1915:
1912:
1907:
1902:
1899:
1896:
1893:
1890:
1886:
1885:
1882:
1879:
1874:
1869:
1866:
1863:
1860:
1857:
1853:
1852:
1850:
1847:
1842:
1837:
1834:
1831:
1828:
1825:
1821:
1820:
1817:
1814:
1809:
1804:
1801:
1798:
1795:
1792:
1788:
1787:
1785:
1782:
1777:
1772:
1769:
1766:
1763:
1760:
1756:
1755:
1752:
1749:
1744:
1739:
1736:
1733:
1730:
1727:
1723:
1722:
1720:
1717:
1712:
1707:
1704:
1701:
1698:
1695:
1691:
1690:
1688:
1685:
1680:
1675:
1672:
1669:
1666:
1663:
1659:
1658:
1656:
1653:
1648:
1643:
1640:
1637:
1634:
1631:
1627:
1626:
1624:
1621:
1616:
1611:
1608:
1605:
1602:
1599:
1595:
1594:
1592:
1589:
1584:
1579:
1576:
1573:
1570:
1567:
1563:
1562:
1560:
1557:
1552:
1547:
1544:
1541:
1538:
1535:
1531:
1530:
1527:
1524:
1519:
1514:
1509:
1504:
1501:
1498:
1475:
1468:
1467:
1455:
1448:
1447:
1446:
1442:
1441:
1440:
1439:
1437:
1434:
1433:
1432:
1427:
1422:
1417:
1411:
1406:
1401:
1395:
1390:
1385:
1383:Bloom syndrome
1371:
1368:
1352:Main article:
1349:
1346:
1314:Main article:
1311:
1308:
1277:Main article:
1274:
1271:
1250:
1247:
1245:
1244:
1234:
1228:
1218:
1208:
1202:
1196:
1190:
1180:
1170:
1164:
1154:
1148:
1142:
1132:
1122:
1116:
1106:
1096:
1090:
1080:
1070:
1064:
1054:
1044:
1034:
1028:
1012:
1006:
996:
990:
980:
970:
964:
958:
952:
946:
940:
934:
924:
918:
912:
902:
896:
886:
880:
870:
864:
858:
848:
835:
825:
815:
805:
795:
789:
779:
773:
763:
753:
743:
733:
723:
717:
711:
705:
699:
693:
687:
677:
671:
661:
655:
645:
639:
633:
627:
621:
611:
601:
595:
589:
583:
577:
571:
565:
559:
549:
543:
533:
527:
513:
510:
500:
493:
482:
479:
476:
475:
472:
470:
467:
464:
461:
455:
454:
451:
449:
446:
443:
440:
434:
433:
430:
428:
425:
422:
419:
413:
412:
409:
407:
404:
401:
398:
392:
391:
388:
386:
383:
380:
377:
371:
370:
367:
364:
359:
354:
349:
323:
320:
318:
315:
271:
270:
258:
252:
251:
239:
233:
232:
226:
225:
220:
214:
213:
208:
202:
201:
196:
190:
189:
184:
178:
177:
173:
172:
167:
161:
160:
155:
149:
148:
143:
137:
136:
131:
125:
124:
120:
119:
112:
106:
105:
100:
96:
95:
88:
79:
78:
73:
65:
64:
60:
59:
53:in human male
50:
42:
41:
32:
24:
23:
15:
9:
6:
4:
3:
2:
4525:
4514:
4511:
4509:
4506:
4505:
4503:
4488:
4485:
4483:
4480:
4478:
4475:
4471:
4468:
4467:
4466:
4463:
4462:
4460:
4456:
4446:
4443:
4441:
4438:
4436:
4433:
4431:
4428:
4426:
4423:
4421:
4418:
4416:
4413:
4411:
4408:
4406:
4403:
4401:
4398:
4396:
4393:
4391:
4388:
4386:
4383:
4381:
4378:
4376:
4373:
4371:
4368:
4367:
4365:
4363:
4359:
4353:
4350:
4348:
4345:
4343:
4340:
4338:
4335:
4333:
4330:
4329:
4327:
4325:
4321:
4315:
4312:
4309:
4305:
4301:
4298:
4297:
4295:
4291:
4285:
4282:
4278:
4275:
4273:
4270:
4268:
4265:
4263:
4260:
4259:
4258:
4255:
4251:
4248:
4246:
4243:
4242:
4241:
4238:
4236:
4233:
4231:
4228:
4227:
4225:
4223:and evolution
4219:
4211:
4208:
4206:
4203:
4201:
4198:
4196:
4193:
4192:
4191:
4188:
4184:
4181:
4179:
4176:
4174:
4171:
4169:
4166:
4164:
4161:
4160:
4159:
4156:
4154:
4151:
4149:
4148:Isochromosome
4146:
4144:
4141:
4139:
4136:
4134:
4131:
4129:
4126:
4124:
4121:
4119:
4116:
4113:
4110:
4108:
4104:
4101:
4099:
4096:
4093:
4089:
4085:
4082:
4081:
4079:
4075:
4069:
4066:
4064:
4061:
4059:
4056:
4054:
4051:
4047:
4044:
4042:
4039:
4038:
4037:
4034:
4032:
4028:
4025:
4023:
4020:
4018:
4015:
4014:
4012:
4006:
4002:
3998:
3991:
3986:
3984:
3979:
3977:
3972:
3971:
3968:
3956:
3953:
3951:
3948:
3944:
3941:
3940:
3939:
3936:
3935:
3933:
3929:
3925:
3921:
3919:
3915:
3905:
3902:
3900:
3897:
3896:
3894:
3892:
3888:
3882:
3879:
3877:
3874:
3872:
3869:
3867:
3864:
3862:
3859:
3857:
3854:
3852:
3849:
3847:
3844:
3842:
3839:
3837:
3834:
3832:
3829:
3827:
3824:
3822:
3819:
3817:
3814:
3812:
3809:
3807:
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3103:
3097:
3093:
3092:
3084:
3077:
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3044:
3040:
3034:
3020:on 2017-09-06
3019:
3015:
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2964:
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2810:
2804:
2790:on 2017-06-29
2789:
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2222:
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2208:
2205:
2200:
2195:
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2186:
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2180:
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2176:
2173:
2168:
2163:
2160:
2157:
2154:
2151:
2148:
2147:
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2140:
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2130:
2127:
2124:
2121:
2118:
2115:
2114:
2111:
2108:
2103:
2098:
2095:
2092:
2089:
2086:
2083:
2082:
2078:
2075:
2070:
2065:
2062:
2059:
2056:
2053:
2050:
2049:
2046:
2043:
2038:
2033:
2030:
2027:
2024:
2021:
2018:
2017:
2013:
2010:
2005:
2000:
1997:
1994:
1991:
1988:
1985:
1984:
1981:
1978:
1973:
1968:
1965:
1962:
1959:
1956:
1953:
1952:
1948:
1945:
1940:
1935:
1932:
1929:
1926:
1923:
1920:
1919:
1916:
1913:
1908:
1903:
1900:
1897:
1894:
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1883:
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1867:
1864:
1861:
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1838:
1835:
1832:
1829:
1826:
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1818:
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1810:
1805:
1802:
1799:
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1793:
1790:
1789:
1786:
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1721:
1718:
1713:
1708:
1705:
1702:
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1609:
1606:
1603:
1600:
1597:
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1574:
1571:
1568:
1565:
1564:
1561:
1558:
1553:
1548:
1545:
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1539:
1536:
1533:
1532:
1528:
1525:
1520:
1515:
1510:
1505:
1502:
1499:
1496:
1495:
1491:
1480:
1472:
1463:
1459:
1452:
1431:
1428:
1426:
1423:
1421:
1418:
1415:
1412:
1410:
1407:
1405:
1402:
1399:
1396:
1394:
1391:
1389:
1388:Breast cancer
1386:
1384:
1381:
1380:
1379:
1376:
1367:
1365:
1361:
1355:
1345:
1341:
1337:
1333:
1331:
1327:
1323:
1317:
1307:
1304:
1300:
1296:
1293:
1288:
1286:
1280:
1270:
1268:
1264:
1260:
1256:
1242:
1238:
1235:
1232:
1229:
1226:
1222:
1219:
1216:
1212:
1209:
1206:
1203:
1200:
1197:
1194:
1191:
1188:
1184:
1181:
1178:
1174:
1171:
1168:
1165:
1162:
1158:
1155:
1152:
1149:
1146:
1143:
1140:
1136:
1133:
1130:
1126:
1123:
1121:: stereocilin
1120:
1117:
1114:
1110:
1107:
1104:
1100:
1097:
1094:
1091:
1088:
1084:
1081:
1078:
1074:
1071:
1068:
1065:
1062:
1058:
1055:
1052:
1048:
1045:
1042:
1038:
1035:
1032:
1029:
1026:
1025:
1024:S. cerevisiae
1020:
1016:
1013:
1010:
1007:
1004:
1000:
997:
994:
991:
988:
984:
981:
978:
974:
971:
968:
965:
962:
959:
956:
953:
950:
947:
944:
941:
938:
935:
932:
928:
925:
922:
919:
916:
913:
910:
906:
903:
900:
897:
894:
890:
887:
884:
881:
878:
874:
871:
868:
865:
862:
859:
856:
852:
849:
846:
843:
839:
836:
833:
829:
826:
823:
819:
816:
813:
809:
806:
803:
799:
796:
793:
790:
787:
783:
780:
777:
774:
771:
767:
764:
761:
757:
754:
751:
747:
744:
741:
737:
734:
731:
727:
724:
721:
718:
715:
712:
709:
706:
703:
700:
697:
694:
691:
688:
685:
681:
678:
675:
672:
669:
665:
662:
659:
656:
653:
649:
646:
643:
640:
637:
634:
631:
628:
625:
622:
619:
615:
612:
609:
605:
602:
599:
596:
593:
590:
587:
584:
581:
578:
575:
572:
569:
566:
563:
560:
557:
553:
550:
547:
544:
541:
537:
534:
531:
528:
525:
521:
517:
514:
511:
508:
504:
501:
498:
495:
494:
492:
488:
473:
471:
468:
465:
462:
460:
457:
456:
452:
450:
447:
444:
441:
439:
436:
435:
431:
429:
426:
423:
420:
418:
415:
414:
410:
408:
405:
402:
399:
397:
394:
393:
389:
387:
384:
381:
378:
376:
373:
372:
369:Release date
368:
365:
363:
360:
358:
355:
353:
350:
348:Estimated by
347:
346:
343:
341:
337:
333:
329:
314:
312:
308:
304:
299:
297:
293:
289:
285:
281:
277:
276:Chromosome 15
267:
263:
259:
257:
253:
248:
244:
240:
238:
234:
231:
227:
224:
223:Chromosome 15
221:
219:
215:
212:
211:Chromosome 15
209:
207:
203:
200:
199:Chromosome 15
197:
195:
191:
188:
187:Chromosome 15
185:
183:
179:
174:
171:
168:
166:
162:
159:
156:
154:
150:
147:
144:
142:
138:
135:
132:
130:
126:
121:
116:
113:
111:
107:
104:
101:
97:
93:
89:
87:
80:
75:99,753,195 bp
74:
71:
66:
61:
56:
48:
43:
36:
30:
25:
22:Chromosome 15
20:
4189:
4157:
3997:Cytogenetics
3938:Human genome
3845:
3751:Human genome
3710:. Retrieved
3706:
3692:. Retrieved
3688:the original
3683:
3644:
3640:
3611:
3607:
3572:
3568:
3539:
3535:
3503:(2): 87–95.
3500:
3496:
3459:
3455:
3420:
3416:
3387:
3383:
3350:(1): 85–91.
3347:
3343:
3304:
3300:
3264:(14): 1–20.
3261:
3257:
3245:
3236:
3232:
3225:
3217:
3212:, generally
3205:
3201:
3172:
3167:": Long arm.
3164:
3160:
3155:
3120:
3110:
3090:
3083:
3070:
3057:
3046:. Retrieved
3042:
3033:
3022:. Retrieved
3018:the original
3013:
3004:
2980:(6): 262–6.
2977:
2973:
2963:
2954:
2948:. Retrieved
2937:
2928:
2917:. Retrieved
2915:. 2017-05-19
2912:
2903:
2892:. Retrieved
2890:. 2017-05-19
2887:
2878:
2867:. Retrieved
2865:. 2017-05-19
2862:
2853:
2842:. Retrieved
2840:. 2018-02-28
2837:
2828:
2817:. Retrieved
2815:. 2017-03-29
2812:
2803:
2792:. Retrieved
2788:the original
2783:
2774:
2737:
2733:
2723:
2685:
2678:
2667:. Retrieved
2665:. 2016-09-08
2663:Homo sapiens
2662:
2658:
2638:
2623:
2614:
2595:
1377:
1373:
1357:
1342:
1338:
1334:
1326:hypogonadism
1319:
1305:
1301:
1297:
1289:
1282:
1263:beyond genes
1252:
1022:
895:MicroRNA 627
879:MicroRNA 7-2
490:
325:
300:
275:
274:
4210:Polycentric
4200:Monocentric
4183:Holocentric
4178:Acrocentric
4173:Telocentric
4163:Metacentric
4041:Euchromatin
4001:chromosomes
3497:J Med Genet
3301:J Med Genet
2734:Genome Biol
2609:introducing
2560:101,991,189
1425:Tyrosinemia
1398:Loeys–Dietz
1360:other names
1239:: encoding
1223:: encoding
1213:: encoding
1185:: encoding
1175:: encoding
1159:: encoding
1137:: encoding
1127:: encoding
1115:Snurportin1
1111:: encoding
1101:: encoding
1085:: encoding
1075:: encoding
1059:: encoding
1049:: encoding
1039:: encoding
1017:: encoding
1001:: encoding
985:: encoding
975:: encoding
929:: encoding
907:: encoding
891:: encoding
875:: encoding
853:: encoding
840:: encoding
830:: encoding
810:: encoding
784:: encoding
768:: encoding
758:: encoding
738:: encoding
682:: encoding
666:: encoding
650:: encoding
616:: encoding
606:: encoding
554:: encoding
538:: encoding
505:: encoding
474:2017-05-19
453:2018-02-28
432:2017-03-29
411:2017-05-12
390:2016-09-08
362:Pseudogenes
280:chromosomes
115:Acrocentric
4502:Categories
4362:Centromere
4293:Structures
4272:Polyploidy
4262:Aneuploidy
4063:Nucleosome
4053:Chromosome
3712:2017-05-06
3694:2017-05-06
3536:Genet Test
3417:Pediatrics
3229:Centromere
3048:2022-02-22
3024:2017-09-05
2950:2009-09-26
2919:2017-05-20
2894:2017-05-20
2869:2017-05-20
2844:2018-03-16
2819:2017-05-19
2794:2017-05-19
2740:(5): 206.
2669:2017-05-28
2592:references
2573:References
2555:98,000,001
2527:98,000,000
2522:93,800,001
2495:93,800,000
2490:88,500,001
2462:88,500,000
2457:84,700,001
2430:84,700,000
2425:81,400,001
2397:81,400,000
2392:78,000,001
2365:78,000,000
2360:76,300,001
2332:76,300,000
2327:74,900,001
2300:74,900,000
2295:72,400,001
2267:72,400,000
2262:67,200,001
2235:67,200,000
2230:67,000,001
2202:67,000,000
2197:66,900,001
2170:66,900,000
2165:63,400,001
2137:63,400,000
2132:59,000,001
2105:59,000,000
2100:58,800,001
2072:58,800,000
2067:52,600,001
2040:52,600,000
2035:49,200,001
2007:49,200,000
2002:44,500,001
1975:44,500,000
1970:43,300,001
1942:43,300,000
1937:42,500,001
1910:42,500,000
1905:39,800,001
1877:39,800,000
1872:33,400,001
1845:33,400,000
1840:30,900,001
1812:30,900,000
1807:30,000,001
1780:30,000,000
1775:27,800,001
1747:27,800,000
1742:25,500,001
1715:25,500,000
1710:20,500,001
1683:20,500,000
1678:19,000,001
1651:19,000,000
1646:17,500,001
1619:17,500,000
1322:polyphagia
485:See also:
288:base pairs
118:(19.0 Mbp)
4314:Protamine
4221:Processes
4205:Dicentric
4058:Chromatid
4036:Chromatin
4017:Karyotype
3210:G banding
2974:Genet Med
1614:9,700,001
1587:9,700,000
1582:4,200,001
1555:4,200,000
1330:hypotonia
1205:Ube3a-ATS
820:encoding
818:LINC00926
800:encoding
748:encoding
524:neocortex
516:ARHGAP11B
481:Gene list
305:gene for
243:NC_000015
170:Gene list
158:Gene list
146:Gene list
134:Gene list
55:karyogram
35:G-banding
4458:See also
4300:Telomere
4267:Euploidy
4195:Acentric
4092:allosome
4084:Autosome
4010:concepts
3768:Autosome
3663:10594876
3599:10712201
3556:10495933
3527:12566516
3484:20832857
3476:11180221
3447:14993551
3404:11275459
3374:15607424
3344:Genomics
3331:12920063
3288:16038620
3239:: Stalk.
3147:16666470
2996:11258627
2766:20441615
1529:Density
1521:Basepair
1516:Basepair
899:MIR9-3HG
845:Mesoderm
792:KIAA1024
568:C15orf54
562:C15orf32
552:C15orf15
526:folding.
311:asprosin
262:CM000677
103:Autosome
86:of genes
68:Length (
63:Features
4470:Plasmid
4324:Histone
4235:Meiosis
4230:Mitosis
3628:9754629
3590:1288168
3518:1735357
3438:6743499
3365:6800218
3322:1735542
3279:6750281
3222:CG-rich
3214:AT-rich
2838:UniProt
2757:2898077
2605:improve
1490:G-bands
1458:Ensembl
1241:protein
1225:protein
1215:protein
1187:protein
1177:protein
1161:protein
1141:Synemin
1139:protein
1129:protein
1113:protein
1103:protein
1093:SLC24A5
1087:protein
1061:protein
1051:protein
1041:protein
1019:protein
1003:protein
987:protein
973:PTPLAD1
955:PLA2G4E
949:PLA2G4D
943:PIGBOS1
931:protein
909:protein
893:protein
883:MIR1282
877:protein
855:protein
842:protein
832:protein
822:protein
802:protein
788:KATNBL1
786:protein
782:KATNBL1
760:protein
750:protein
740:protein
720:HDGFRP3
714:GOLGA8H
684:protein
668:protein
664:FAM214A
652:protein
636:CYP19A1
618:protein
556:protein
540:protein
536:ARPP-19
438:UniProt
417:Ensembl
366:Source
256:GenBank
182:Ensembl
153:UniProt
77:(CHM13)
4031:Genome
4022:Ploidy
3661:
3626:
3597:
3587:
3554:
3525:
3515:
3482:
3474:
3445:
3435:
3402:
3372:
3362:
3329:
3319:
3286:
3276:
3145:
3135:
3098:
2994:
2764:
2754:
2693:
2594:, but
1526:Stain
1518:start
1508:start
1364:autism
1285:ataxia
1237:ZNF592
1211:UNC13C
1193:UBE2Q2
1173:TMCO5A
1167:TM6SF1
1151:TGFBR2
1099:SNAPC5
1077:enzyme
1067:SCAPER
1057:SCZD10
1047:SCAMP5
1037:SCAMP2
1031:RTFDC1
977:enzyme
915:NUSAP1
889:MIR627
873:MIR7-2
828:MESDC2
812:enzyme
770:enzyme
736:HMG20A
630:CRAT37
614:COMMD4
608:enzyme
507:enzyme
503:ACSBG1
284:humans
237:RefSeq
194:Entrez
4308:TINF2
4077:Types
4008:Basic
3480:S2CID
3237:stalk
3178:locus
3143:S2CID
2220:22.33
2187:22.32
2155:22.31
1591:stalk
1523:stop
1513:stop
1503:Band
1497:Chr.
1416:(SYS)
1292:UBE3A
1231:WDR76
1221:VPS39
1199:UBE3A
1183:TMED3
1125:SUHW4
1083:SERF2
1073:SENP8
999:RMDN3
993:RAD51
983:PYGO1
967:POTEB
927:PDCD7
905:NIPA2
867:MCTP2
861:MCPH4
851:MFAP1
838:MESP1
808:LCMT2
798:LARP6
766:ITPKA
746:IDDM3
702:GLC1I
696:GCHFR
680:FOXB1
642:DTWD1
624:CPEB1
592:CHSY1
580:CELF6
574:CAPN3
530:ARPIN
497:AAGAB
317:Genes
296:cells
266:FASTA
247:FASTA
90:561 (
4090:(or
3659:PMID
3624:PMID
3595:PMID
3552:PMID
3523:PMID
3472:PMID
3443:PMID
3400:PMID
3370:PMID
3327:PMID
3284:PMID
3226:acen
3218:gneg
3206:gpos
3133:ISBN
3096:ISBN
2992:PMID
2913:NCBI
2888:NCBI
2863:NCBI
2762:PMID
2691:ISBN
2659:NCBI
2564:gneg
2551:6070
2548:5860
2545:26.3
2531:gpos
2518:5860
2515:5649
2512:26.2
2499:gneg
2486:5649
2483:5379
2480:26.1
2466:gpos
2453:5379
2450:5169
2447:25.3
2434:gneg
2421:5169
2418:5048
2415:25.2
2401:gpos
2388:5048
2385:4928
2382:25.1
2369:gneg
2356:4928
2353:4808
2350:24.3
2336:gpos
2323:4808
2320:4748
2317:24.2
2304:gneg
2291:4748
2288:4613
2285:24.1
2271:gpos
2258:4613
2255:4507
2239:gneg
2226:4507
2223:4357
2206:gpos
2193:4357
2190:4252
2174:gneg
2161:4252
2158:4087
2141:gpos
2128:4087
2125:3982
2122:22.2
2109:gneg
2096:3982
2093:3846
2090:22.1
2076:gpos
2063:3846
2060:3621
2057:21.3
2044:gneg
2031:3621
2028:3471
2025:21.2
2011:gpos
1998:3471
1995:3245
1992:21.1
1979:gneg
1966:3245
1963:3065
1960:15.3
1946:gpos
1933:3065
1930:2975
1927:15.2
1914:gneg
1901:2975
1898:2765
1895:15.1
1881:gpos
1868:2765
1865:2524
1849:gneg
1836:2524
1833:2284
1830:13.3
1816:gpos
1803:2284
1800:2164
1797:13.2
1784:gneg
1771:2164
1768:1968
1765:13.1
1751:gpos
1738:1968
1735:1773
1719:gneg
1706:1773
1703:1487
1700:11.2
1687:acen
1674:1487
1671:1382
1668:11.1
1655:acen
1642:1382
1639:1142
1636:11.1
1623:gvar
1610:1142
1604:11.2
1559:gvar
1511:ISCN
1506:ISCN
1500:Arm
1257:and
1157:TMC3
1145:TEX9
1135:SYNM
1119:STRC
1109:SPN1
1015:RTF1
1009:RNR3
937:PIF1
921:OCA2
756:IMP3
726:HEXA
708:GLCE
690:GATM
674:FBN1
648:ELL3
604:ClpX
598:CLK3
546:B2MR
469:594
459:NCBI
427:508
406:433
396:HGNC
375:CCDS
340:CCDS
301:The
218:UCSC
206:NCBI
165:NCBI
141:HGNC
129:CCDS
99:Type
92:CCDS
4342:H2B
4337:H2A
3649:doi
3616:doi
3585:PMC
3577:doi
3544:doi
3513:PMC
3505:doi
3464:doi
3433:PMC
3425:doi
3421:113
3392:doi
3360:PMC
3352:doi
3317:PMC
3309:doi
3274:PMC
3266:doi
3233:var
3125:doi
2982:doi
2752:PMC
2742:doi
2534:50
2469:50
2404:50
2339:25
2274:25
2209:25
2144:25
2079:75
2014:75
1949:25
1884:75
1819:50
1754:50
1607:631
1578:631
1575:270
1546:270
961:PML
776:IVD
658:FAH
586:CHP
466:716
463:629
442:601
424:992
421:605
403:328
400:559
379:561
292:DNA
282:in
84:No.
4504::
4385:C2
4380:C1
4352:H4
4347:H3
4332:H1
4302::
3999::
3881:22
3876:21
3871:20
3866:19
3861:18
3856:17
3851:16
3846:15
3841:14
3836:13
3831:12
3826:11
3821:10
3705:.
3682:.
3657:.
3645:87
3643:.
3639:.
3622:.
3612:81
3610:.
3593:.
3583:.
3573:66
3571:.
3567:.
3550:.
3538:.
3521:.
3511:.
3501:40
3499:.
3495:.
3478:.
3470:.
3460:97
3458:.
3441:.
3431:.
3419:.
3415:.
3398:.
3388:24
3386:.
3368:.
3358:.
3348:85
3346:.
3342:.
3325:.
3315:.
3305:40
3303:.
3299:.
3282:.
3272:.
3260:.
3256:.
3231:.
3185:^
3141:.
3131:.
3119:.
3041:.
3012:.
2990:.
2976:.
2972:.
2953:.
2942:.
2936:.
2911:.
2886:.
2861:.
2836:.
2811:.
2782:.
2760:.
2750:.
2738:11
2736:.
2732:.
2705:^
2657:.
2646:^
2542:q
2539:15
2509:q
2506:15
2477:q
2474:15
2444:q
2441:15
2412:q
2409:15
2379:q
2376:15
2347:q
2344:15
2314:q
2311:15
2282:q
2279:15
2252:23
2249:q
2246:15
2217:q
2214:15
2184:q
2181:15
2152:q
2149:15
2119:q
2116:15
2087:q
2084:15
2054:q
2051:15
2022:q
2019:15
1989:q
1986:15
1957:q
1954:15
1924:q
1921:15
1892:q
1889:15
1862:14
1859:q
1856:15
1827:q
1824:15
1794:q
1791:15
1762:q
1759:15
1732:12
1729:q
1726:15
1697:q
1694:15
1665:q
1662:15
1633:p
1630:15
1601:p
1598:15
1572:12
1569:p
1566:15
1540:13
1537:p
1534:15
1464:).
1460:,
1269:.
448:—
385:—
268:)
249:)
70:bp
4445:T
4440:Q
4435:P
4430:O
4425:N
4420:M
4415:K
4410:J
4405:I
4400:H
4395:F
4390:E
4375:B
4370:A
4310:)
4306:(
4105:/
4086:/
4029:/
3989:e
3982:t
3975:v
3904:Y
3899:X
3816:9
3811:8
3806:7
3801:6
3796:5
3791:4
3786:3
3781:2
3776:1
3743:e
3736:t
3729:v
3715:.
3697:.
3665:.
3651::
3630:.
3618::
3601:.
3579::
3558:.
3546::
3540:3
3529:.
3507::
3486:.
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3449:.
3427::
3406:.
3394::
3376:.
3354::
3333:.
3311::
3290:.
3268::
3262:7
3196:.
3180:.
3165:q
3161:p
3159:"
3149:.
3127::
3104:.
3051:.
3027:.
2998:.
2984::
2978:1
2922:.
2897:.
2872:.
2847:.
2822:.
2797:.
2768:.
2744::
2699:.
2672:.
2630:)
2624:(
2619:)
2615:(
2601:.
1550:1
1543:0
1481:.
1207::
1027:)
732:)
722::
644::
445:—
382:—
264:(
245:(
94:)
72:)
57:.
37:.
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