Knowledge

Biofortification

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cousin so it can be taken to market earlier. It can also be done through public health education, making the benefits of eating biofortified foods apparent to consumers. Trials suggest that the rural poor “will consume biofortified versions of food staples even if the color of the food has been changed…if they are educated as to the benefit”. While other micronutrients such as zinc or iron can be added to crops without noticeably changing their taste or appearance, some researchers emphasize the importance of ensuring that consumers do not think that their food has been altered without their authorization or knowledge.
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carbohydrate staples.” This may seem irresponsible, as lack of access to a diverse and balanced diet is the major cause of malnutrition. As a result these critics urge caution, and the use of biofortification as part of a larger strategy involving diversification of foods in low and middle-income countries. Advocates of biofortification accept this as a long term strategy, but state that substantially increasing diet diversity will take “many decades and untold billions of dollars”, and that biofortification could be an effective strategy to help reduce micronutrient malnutrition.
180:. Although these approaches have proven successful when dealing with the urban poor, they tend to require access to effective markets and healthcare systems which often just do not exist in rural areas. Biofortification is also fairly cost effective after an initial large research investment – where seeds can be distributed, the “implementation costs are nil or negligible”, as opposed to supplementation which is comparatively expensive and requires continued financing over time, which may be jeopardized by fluctuating political interest. 757: 740: 723: 20: 88:
measurable positive impact on human health. As such, they must be developed with the involvement of nutritionists who study whether the consumers of the improved crop can absorb the extra nutrients, and the extent to which storage, processing, and cooking of the crops affect their available nutrient levels. Bread wheat with high grain iron and zinc has been developed through radiation breeding.
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white maize is eaten by humans and yellow maize is negatively associated with animal feed or food aid, or where white-fleshed sweet potato is preferred to its moister, orange-fleshed counterpart. Some qualities may be relatively simple to mitigate or breed out of biofortified crops according to consumer demand, such as the moistness of the sweet potato, whereas others cannot be.
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Where this is the case, care must be taken to convince the local farmers and consumers that the crop in question is worth growing and consuming. This can be done through improving the cultivation qualities of the plant, for example making the orange sweet-potato mature earlier than its white-fleshed
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There may occasionally be difficulties in getting biofortified foods to be accepted if they have different characteristics to their unfortified counterparts. For example, vitamin A enhanced foods are often dark yellow or orange in color – this for example is problematic for many in Africa, where
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Verma, Shailender Kumar; Kumar, Satish; Sheikh, Imran; Malik, Sachin; Mathpal, Priyanka; Chugh, Vishal; Kumar, Sundip; Prasad, Ramasare; Dhaliwal, Harcharan Singh (2016-03-03). "Transfer of useful variability of high grain iron and zinc from Aegilops kotschyi into wheat through seed irradiation
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are common in low and middle-income countries and affect billions of people. These can lead to, amongst other symptoms, a higher incidence of blindness, a weaker immune system, stunted growth and impaired cognitive development. The poor, particularly the rural poor, tend to subsist on a diet of
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because it focuses on making plant foods more nutritious as the plants are growing, rather than having nutrients added to the foods when they are being processed. This is an important improvement on ordinary fortification when it comes to providing nutrients for the rural poor, who rarely have
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for existing varieties of crops which are naturally high in nutrients. They then crossbreed these high-nutrient varieties with high-yielding varieties of crops, to provide a seed with high yields and increased nutritional value. Crops must be bred with sufficient amounts of nutrients to have a
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Some have criticized biofortification programs because they may encourage “further simplification of human diets and food systems”, because “ a strategy that aims to concentrate more nutrients in few staple foods may contribute to further simplifying diets already overly dependent on a few
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biofortified with beta-carotene reduced the incidence of vitamin A deficiency in children by 24%. In two separate randomized clinical trials in India, eating iron- and zinc- biofortified
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have been looking for ways to boost the low selenium levels in British grains, and have been working to help develop a grain to be used in making bread biofortified with selenium.
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Mehta, S; Huey, SL; Ghugre, PS; Potdar, RD; Venkatramanan, S; Krisher; ruth; Chopra; Thorat; Thakker; Johnson; Powis; Raveendran; Haas; Finkelstein (April 2022).
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in the development of biofortified crops, primarily use conventional breeding techniques, and have not yet spent more than 15% of their research budget on
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Wolfgang H. Pfeiffer & Bonnie McClafferty, ‘Biofortification: Breeding Micronutrient-Dense Crops’, in Manjit S. Kang & P.M. Priyadarshan (eds.),
439: 569:"A randomized trial of iron- and zinc-biofortified pearl millet-based complementary feeding in children aged 12 to 18 months living in urban slums" 827: 105:
is an example of a GM crop developed for its nutritional value. The latest version of golden rice contains genes from a common soil bacterium
273:"Biofortified Crops Generated by Breeding, Agronomy, and Transgenic Approaches Are Improving Lives of Millions of People around the World" 700:‘Patterns of Political Response to Biofortified Varieties of Crops Produced with Different Breeding Techniques and Agronomic Traits’ 503:‘Patterns of Political Response to Biofortified Varieties of Crops Produced with Different Breeding Techniques and Agronomic Traits’ 204: 640: 702: 505: 27:, an example of biofortification using genetic engineering. The golden color of the grains comes from the increased amounts of 526:
Finkelstein, J; Mehta, S; Udipi, S; Ghugre, PS; Luna, SV; Wenger, MJ; Murray-Kolb, LE; Przybyszewski, E; Haas, J (July 2015).
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This method is prevalent at present, as it is less controversial than genetically engineering crops. HarvestPlus, a major
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Research on this approach is being undertaken internationally, with major efforts ongoing in Brazil, China and India.
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Garg, Monika; Sharma, Natasha; Sharma, Saloni; Kapoor, Payal; Kumar, Aman; Chunduri, Venkatesh; Arora, Priya (2018).
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which can be converted by the body into vitamin A. Golden rice is being developed as a potential new way to address
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access to commercially fortified foods. As such, biofortification is seen as an upcoming strategy for dealing with
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concentrations in younger male children, and in children ages 12-18 months who were iron-deficient at baseline.
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estimated that biofortification could help cure the 2 billion people suffering from iron deficiency-induced
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This approach may have advantages over other health interventions such as providing foods
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Biofortification: Harnessing Agricultural Technology to Improve the Health of the Poor
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was found to improve iron status among school-aged children and was found to improve
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Plants can be bred by selective breeding. In this method, plant breeders search
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Penelope Nestel, Howarth E. Bouis, J. V. Meenakshi, & Wolfgang Pfeiffer,
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Bonnie McClafferty & Yassir Islam, ‘Fighting the Hidden Hunger’, in
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Bonnie McClafferty & Yassir Islam, ‘Fighting the Hidden Hunger’, in
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when conventional methods fail to meet nutritional requirements.
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Some people, while not opposed to biofortification itself, are
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The WHO Vitamin and Mineral Nutrition Information System
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Directory of publications related to biofortification
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Carl Pray, Robert Paarlberg, & Laurian Unnevehr,
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Carl Pray, Robert Paarlberg, & Laurian Unnevehr,
355: 207:, including biofortified ones such as golden rice. 63:in low and middle-income countries. In the case of 132:Deficiencies of various micronutrients, including 127: 1246: 656:‘HarvestPlus aid for boosting nutrition levels’ 266: 264: 821: 764:, vol. 32, issue 1, (February 2007), pp. 2-3. 111:and maize, and contains increased levels of 730:, vol. 32, issue 1, (February 2007), p. 11. 261: 16:Breeding crops for higher nutritional value 828: 814: 747:, vol. 32, issue 1, (February 2007), p. 3. 359:International Journal of Radiation Biology 346:, Blackwell Publishing, (2007), pp. 63-64. 756:Timothy Johns & Pablo B. Eyzaguirre, 739:Timothy Johns & Pablo B. Eyzaguirre, 722:Timothy Johns & Pablo B. Eyzaguirre, 584: 543: 298: 288: 685:Jocelyn C. Zuckerman, ‘Mission Man’, in 673:The Researcher, the Farmer and the Baker 425:Jocelyn C. Zuckerman, ‘Mission Man’, in 186: 18: 622:‘Biofortification of Staple Food Crops’ 616: 614: 612: 457:International Rice Research Institute: 438:International Rice Research Institute: 333:, Section 5, Retrieved on July 22, 2008 1247: 468: 466: 408: 406: 404: 205:critical of genetically modified foods 809: 609: 628:, vol. 136, no. 4, (2006), p. 1066. 463: 401: 250:Bill & Melinda Gates Foundation 23:The far bowl on the right contains 13: 778:, IFPRI and CIAT pamphlet, (2002). 46:. This can be done either through 14: 1266: 784: 713:, vol. 10, no. 3, (2007), p. 138. 516:, vol. 10, no. 3, (2007), p. 137. 835: 54:. Biofortification differs from 767: 750: 733: 716: 692: 679: 665: 649: 631: 560: 519: 495: 479: 128:Low and middle-income countries 48:conventional selective breeding 451: 432: 419: 349: 336: 315: 78: 61:deficiencies of micronutrients 1: 371:10.3109/09553002.2016.1135263 676:, Retrieved on July 22, 2008 662:, Retrieved on July 22, 2008 7: 903:Wernicke–Korsakoff syndrome 344:Breeding Major Food Staples 222: 198: 10: 1271: 689:, (November 2007), p. 104. 586:10.1016/j.clnu.2022.02.014 429:, (November 2007), p. 197. 174:fortified after processing 97:genetically modified crops 1211: 1176: 1074: 1005: 908:Wernicke's encephalopathy 882: 873: 843: 638:HarvestPlus China website 476:, (February 2008), p. 26. 445:November 2, 2012, at the 416:, (February 2008), p. 27. 643:August 20, 2008, at the 626:The Journal of Nutrition 486:‘The New Face of Hunger’ 255: 234:Micronutrient deficiency 42:crops to increase their 660:The Hindu Business Line 290:10.3389/fnut.2018.00012 122: 85:seed or germplasm banks 277:Frontiers in Nutrition 56:ordinary fortification 32: 1084:Electrolyte imbalance 952:Pyridoxine deficiency 926:Riboflavin deficiency 545:10.3945/jn.114.208009 492:, (April 17th, 2008). 329:July 5, 2008, at the 193:University of Warwick 187:High-income countries 145:staple crops such as 22: 1062:Vitamin K deficiency 1056:Vitamin E deficiency 1033:Vitamin D deficiency 1014:Vitamin A deficiency 913:Korsakoff's syndrome 117:vitamin A deficiency 459:Golden Rice at IRRI 191:Researchers at the 52:genetic engineering 1076:Mineral deficiency 875:Vitamin deficiency 705:2020-07-12 at the 508:2020-07-12 at the 33: 1242: 1241: 1191:Failure to thrive 1186:Delayed milestone 1070: 1069: 1048:Harrison's groove 978:Folate deficiency 965:Biotin deficiency 440:About Golden Rice 236:("Hidden hunger") 44:nutritional value 1262: 880: 879: 830: 823: 816: 807: 806: 779: 771: 765: 754: 748: 737: 731: 720: 714: 696: 690: 683: 677: 669: 663: 653: 647: 635: 629: 618: 607: 606: 588: 564: 558: 557: 547: 538:(7): 1576–1581. 523: 517: 499: 493: 483: 477: 470: 461: 455: 449: 436: 430: 423: 417: 410: 399: 398: 353: 347: 340: 334: 323:HarvestPlus FAQs 319: 313: 312: 302: 292: 268: 36:Biofortification 1270: 1269: 1265: 1264: 1263: 1261: 1260: 1259: 1245: 1244: 1243: 1238: 1207: 1172: 1066: 1001: 994: 987: 974: 961: 948: 935: 922: 894: 869: 846: 839: 834: 787: 782: 772: 768: 755: 751: 738: 734: 721: 717: 707:Wayback Machine 697: 693: 684: 680: 670: 666: 654: 650: 645:Wayback Machine 636: 632: 619: 610: 565: 561: 524: 520: 510:Wayback Machine 500: 496: 484: 480: 471: 464: 456: 452: 447:Wayback Machine 437: 433: 424: 420: 411: 402: 354: 350: 341: 337: 331:Wayback Machine 320: 316: 269: 262: 258: 225: 201: 189: 176:, or providing 130: 125: 81: 38:is the idea of 17: 12: 11: 5: 1268: 1258: 1257: 1240: 1239: 1237: 1236: 1231: 1226: 1221: 1215: 1213: 1209: 1208: 1206: 1205: 1204: 1203: 1193: 1188: 1182: 1180: 1174: 1173: 1171: 1170: 1165: 1164: 1163: 1161:Keshan disease 1153: 1148: 1143: 1138: 1133: 1128: 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865:Catabolysis 855:Kwashiorkor 796:HarvestPlus 762:Food Policy 745:Food Policy 728:Food Policy 357:approach". 229:Golden rice 178:supplements 103:Golden rice 79:Methodology 25:Golden Rice 1201:Idiopathic 1151:Molybdenum 995:deficiency 884:B vitamins 711:AgBioForum 514:AgBioForum 167:hemoglobin 1131:Manganese 1109:Potassium 1104:Phosphate 1099:Magnesium 991:Vitamin B 603:247116529 573:Clin Nutr 379:0955-3002 134:vitamin A 1249:Category 1229:Cachexia 1219:Anorexia 1168:Fluorine 1156:Selenium 1146:Chromium 1094:Chloride 939:Pellagra 898:Beriberi 860:Marasmus 703:Archived 641:Archived 595:35299084 554:25948782 506:Archived 443:Archived 395:10873152 387:26883304 327:Archived 309:29492405 223:See also 199:Problems 40:breeding 1212:General 1089:Calcium 1038:Rickets 687:Gourmet 427:Gourmet 300:5817065 108:Erwinia 1178:Growth 1141:Iodine 1136:Copper 1114:Sodium 1027:Scurvy 601:  593:  552:  532:J Nutr 393:  385:  377:  307:  297:  283:: 12. 140:, and 73:anemia 67:, the 1255:Crops 1006:Other 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Index


Golden Rice
beta-carotene
breeding
nutritional value
conventional selective breeding
genetic engineering
ordinary fortification
deficiencies of micronutrients
iron
WHO
anemia
seed or germplasm banks
NGO
genetically modified crops
Golden rice
Erwinia
beta-carotene
vitamin A deficiency
vitamin A
zinc
iron
rice
wheat
maize
sweet potatoes
pearl millet
hemoglobin
fortified after processing
supplements

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