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Arteriovenous oxygen difference

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leads to an increase in the arteriovenous oxygen difference in all individuals. As exercise intensities increase, the muscles increase the amount of oxygen they extract from the blood, and this therefore results in further increases in
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in the early stages of exercise. The bulk of the early increase in oxygen consumption after a sudden change in exercise levels results from increased cardiac output. However it has also been found that the increase in the maximal
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Arterial blood will generally contain an oxygen concentration of around 20 mL/100 mL. Venous blood with an oxygen concentration of 15 mL/100 mL would therefore lead to typical values of the a-vO
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increases. With training the muscles also improve in their ability to extract oxygen from the blood and process the oxygen, possibly due to adaptations of the
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Robertson, Claudia S.; et al. (February 1989). "Cerebral arteriovenous oxygen difference as an estimate of cerebral blood flow in comatose patients".
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mainly due to increased capillarisation. The increase in capillary beds in the muscle means that blood supply to that muscle can be greater and
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diff is millilitres of oxygen per 100 millilitres of blood (mL/100 mL), however, particularly in medical uses, other units may be used, such as
612: 472:"Cardiac output, oxygen consumption and arteriovenous oxygen difference following a sudden rise in exercise level in humans" 205: 63:
are the main factors that allow variation in the body's total oxygen consumption, and are important in measuring
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The arteriovenous oxygen difference is usually taken by comparing the difference in the oxygen concentration of
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Research has shown that following the commencement of exercise there is a delay in the increase of the a-vO
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diff resulting from adaptations to a physical training program can account for most of the difference in
568: 281: 476: 432: 75: 559: 555:"Increased Arteriovenous Oxygen Difference After Physical Training in Coronary Heart Disease" 8: 631: 353: 498: 471: 52: 608: 582: 503: 449: 266: 250: 192:
rather than by taking direct blood samples. In order to do so oxygen consumption (VO
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diff would be obtained as the oxygen content of the blood would have increased.
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diff may instead be taken by comparing blood from the pulmonary artery and the
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to detect gaseous concentrations in exhaled air compared to inhaled air, while
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diff at rest of around 5 mL/100 mL. During intense exercise, however, the a-vO
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Arteriovenous oxygen difference is also used in other areas of study such as
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diff has also been used to determine the effects of physical training in
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extracting far more oxygen from the blood than they do at rest.
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diff can increase to as much as 16 mL/100 mL due to the working
175: 162:= the oxygen concentration of venous blood (deoxygenated blood) 153:= the oxygen concentration of arterial blood (oxygenated blood) 32: 227: 36: 357: 315:
diff only has a marginal impact in the total change in VO
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Alternatively, in order to find the efficiency of the
110:(as an indicator of the typical mixed venous supply). 440:(2). American Association of Neurosurgeons: 222–230. 78:
of oxygen per 100 millilitres of blood (mL/100 mL).
540:, Chapter 11: Chronic Training Adaptations, p. 307. 524:, Chapter 11: Chronic Training Adaptations, p. 304. 332:in subjects participating in sub-maximal exercise. 272:than in untrained individuals. This is a result of 465: 463: 417:, Chapter 4: Acute Responses to Exercise, p. 106. 623: 460: 425: 423: 470:De Cort, S. C; et al. (September 1991). 230:in replenishing blood oxygen levels, the a-vO 420: 553:Detry, Jean-Marie R.; et al. (1971). 548: 546: 576: 532: 530: 497: 429: 409: 407: 405: 238:; in this case a negative value for a-vO 605:Physical Education: VCE Units 3 & 4 602: 543: 469: 624: 527: 514: 402: 245: 603:Malpeli, Robert; et al. (2010). 552: 102:and the oxygen concentration in the 106:from the mixed supply found in the 13: 14: 653: 188:diff may be determined using the 300:and an increase in the muscle's 265:diff is also usually greater in 360:patients, assisting with their 21:arteriovenous oxygen difference 490:10.1113/jphysiol.1991.sp018764 352:diff has been used to measure 335: 81: 1: 396: 74:diff is usually measured in 7: 379: 31:, is the difference in the 10: 658: 596: 569:American Heart Association 446:10.3171/jns.1989.70.2.0222 204:can be determined using a 196:) may be measured using a 181:per millilitre (μmol/mL). 477:The Journal of Physiology 282:slow twitch muscle fibres 578:10.1161/01.cir.44.1.109 433:Journal of Neurosurgery 348:. For example, the a-vO 170:The usual unit for a-vO 113:Put in simple terms: 55:in the body. The a-vO 637:Exercise physiology 354:cerebral blood flow 311:diff, and that a-vO 246:Impacts of exercise 16:Medical measurement 642:Sports terminology 538:Physical Education 522:Physical Education 415:Physical Education 206:Doppler ultrasound 104:deoxygenated blood 614:978-0-17-018692-6 391:Oxygen saturation 374:coronary patients 251:Physical exercise 184:In practice, a-vO 649: 618: 591: 590: 580: 550: 541: 534: 525: 518: 512: 511: 501: 467: 458: 457: 427: 418: 411: 346:medical research 274:aerobic exercise 261:The maximum a-vO 108:pulmonary artery 88:oxygenated blood 657: 656: 652: 651: 650: 648: 647: 646: 622: 621: 615: 599: 594: 551: 544: 535: 528: 519: 515: 468: 461: 428: 421: 412: 403: 399: 382: 371: 351: 338: 329: 323: 318: 314: 310: 264: 257: 248: 241: 233: 218: 214: 195: 187: 173: 160: 151: 140: 133: 127: 84: 73: 68: 58: 35:content of the 28: 17: 12: 11: 5: 655: 645: 644: 639: 634: 620: 619: 613: 598: 595: 593: 592: 542: 526: 513: 459: 419: 400: 398: 395: 394: 393: 388: 381: 378: 369: 349: 337: 334: 327: 321: 316: 312: 308: 290:carbon dioxide 262: 255: 247: 244: 239: 236:pulmonary vein 231: 216: 212: 202:cardiac output 193: 190:Fick Principle 185: 171: 168: 167: 166: 165: 164: 163: 158: 154: 149: 138: 131: 125: 83: 80: 71: 66: 61:cardiac output 56: 41:arterial blood 26: 15: 9: 6: 4: 3: 2: 654: 643: 640: 638: 635: 633: 630: 629: 627: 616: 610: 606: 601: 600: 588: 584: 579: 574: 570: 566: 562: 561: 556: 549: 547: 539: 533: 531: 523: 517: 509: 505: 500: 495: 491: 487: 483: 479: 478: 473: 466: 464: 455: 451: 447: 443: 439: 435: 434: 426: 424: 416: 410: 408: 406: 401: 392: 389: 387: 384: 383: 377: 375: 367: 363: 359: 355: 347: 343: 333: 331: 305: 303: 299: 295: 291: 287: 283: 279: 275: 271: 268: 259: 252: 243: 237: 229: 224: 222: 209: 207: 203: 199: 191: 182: 180: 177: 161: 155: 152: 146: 145: 143: 142: 141: 134: 123: 119: 116: 115: 114: 111: 109: 105: 101: 100:radial artery 97: 93: 89: 79: 77: 69: 62: 54: 51:as the blood 50: 46: 42: 38: 34: 30: 22: 604: 564: 558: 537: 521: 516: 481: 475: 437: 431: 414: 339: 306: 298:mitochondria 292:, and other 260: 249: 225: 210: 183: 169: 156: 147: 136: 129: 121: 117: 112: 85: 45:venous blood 39:between the 24: 20: 18: 571:: 109–118. 560:Circulation 484:: 501–512. 336:In medicine 294:metabolites 288:of oxygen, 278:hypertrophy 276:leading to 82:Measurement 76:millilitres 49:capillaries 632:Cardiology 626:Categories 397:References 368:. The a-vO 198:spirometer 70:. The a-vO 53:circulates 536:Malpeli, 520:Malpeli, 413:Malpeli, 386:Blood gas 366:treatment 362:diagnosis 304:content. 302:myoglobin 286:diffusion 59:diff and 380:See also 358:comatose 342:medicine 270:athletes 96:brachial 43:and the 597:Sources 587:5561413 508:1816384 499:1180211 454:2913221 280:of the 267:trained 221:muscles 144:where: 128:diff = 92:femoral 90:in the 611:  585:  506:  496:  452:  258:diff. 33:oxygen 567:(1). 228:lungs 179:moles 176:micro 98:, or 37:blood 23:, or 609:ISBN 583:PMID 504:PMID 450:PMID 364:and 344:and 320:a-vO 254:a-vO 29:diff 25:a-vO 19:The 573:doi 494:PMC 486:doi 482:441 442:doi 356:in 330:max 628:: 581:. 565:44 563:. 557:. 545:^ 529:^ 502:. 492:. 480:. 474:. 462:^ 448:. 438:70 436:. 422:^ 404:^ 376:. 326:VO 208:. 135:– 94:, 65:VO 617:. 589:. 575:: 510:. 488:: 456:. 444:: 370:2 350:2 328:2 322:2 317:2 313:2 309:2 263:2 256:2 240:2 232:2 217:2 213:2 194:2 186:2 172:2 159:v 157:C 150:a 148:C 139:v 137:C 132:a 130:C 126:2 124:O 122:v 120:- 118:a 72:2 67:2 57:2 27:2

Index

oxygen
blood
arterial blood
venous blood
capillaries
circulates
cardiac output
VO2
millilitres
oxygenated blood
femoral
brachial
radial artery
deoxygenated blood
pulmonary artery
micro
moles
Fick Principle
spirometer
cardiac output
Doppler ultrasound
muscles
lungs
pulmonary vein
Physical exercise
trained
athletes
aerobic exercise
hypertrophy
slow twitch muscle fibres

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