783:
284:
29:
45:
212:
Two endocardial thickenings—anterior and posterior—develop in the bulbus cordis and unite to form a short septum; this joins above with the aortic septum and below with the ventricular septum. The septum grows down into the ventricle as an oblique partition, which ultimately blends with the
803:
186:
Two distal ridge-like thickenings project into the lumen of the tube; these increase in size, and ultimately meet and fuse to form a septum, which takes a spiral course toward the proximal end of the
407:
400:
393:
190:. It divides the distal part of the truncus into two vessels, the aorta and pulmonary artery, which lie side by side above, but near the heart the
380:
230:
The actual mechanism of septation of the outflow tract is poorly understood, but is recognized as a dynamic process with contributions from
813:
251:
106:
549:
259:
221:; while the left ventricle is brought into continuity with the aorta, which communicates with the remaining aortic arches.
650:
481:
53:
to show the growth of the aortic septum. The lowest section is on the left, the highest on the right of the figure.
171:
350:
Jiang X, Rowitch DH, Soriano P, McMahon AP, Sucov HM (2000). "Fate of the mammalian cardiac neural crest...".
247:
315:
Kirby ML, Gale TF, Stewart DE (1983). "Neural crest cells contribute to normal aorticopulmonary septation".
271:
381:
https://web.archive.org/web/20071009000046/http://isc.temple.edu/marino/embryology/Heart98/abnorm_text.htm
516:
293:
773:
101:
808:
611:
147:
606:
496:
113:
616:
526:
486:
239:
213:
ventricular septum in such a way as to bring the bulbus cordis into communication with the
202:
8:
666:
452:
243:
782:
385:
760:
724:
491:
442:
417:
187:
736:
704:
626:
425:
359:
332:
298:
255:
155:
804:
Knowledge articles incorporating text from the 20th edition of Gray's
Anatomy (1918)
744:
732:
684:
511:
457:
324:
242:
interactions. Misalignment of the septum can cause the congenital heart conditions
214:
206:
191:
143:
205:
appear in the proximal part of the truncus arteriosus in the region of the future
755:
521:
209:; the manner in which these are related to the aortic septum is described below.
787:
720:
716:
712:
598:
797:
674:
583:
506:
462:
447:
434:
289:
218:
175:
328:
578:
570:
363:
235:
135:
77:
336:
231:
50:
34:
119:
634:
588:
72:
138:, specifically the cardiac neural crest, and actively separates the
751:
694:
689:
679:
740:
728:
195:
167:
151:
139:
89:
349:
44:
28:
415:
33:
Diagrams to show the development of the septum of the
771:
795:
314:
217:, and through the latter with the sixth pair of
182:. This makes its appearance in three portions.
401:
107:septum_by_E4.0.3.5.0.3.12 E4.0.3.5.0.3.12
408:
394:
252:dextro-Transposition of the great arteries
43:
27:
225:
550:Protein signalling in heart development
796:
288:This article incorporates text in the
389:
260:anomalous pulmonary venous connection
814:Embryology of cardiovascular system
13:
651:Vascular remodelling in the embryo
14:
825:
374:
781:
482:Primary interventricular foramen
282:
49:Transverse sections through the
134:is developmentally formed from
343:
308:
1:
277:
248:persistent truncus arteriosus
272:Aortopulmonary septal defect
161:
7:
517:Primary interatrial foramen
296:of the 20th edition of
265:
10:
830:
703:
663:
643:
625:
597:
569:
562:
537:
471:
433:
424:
112:
100:
88:
83:
71:
63:
58:
42:
26:
21:
612:Posterior cardinal vein
545:Aorticopulmonary septum
329:10.1126/science.6844926
148:interventricular septum
132:aorticopulmonary septum
95:septum aorticopulmonale
22:Aorticopulmonary septum
607:Anterior cardinal vein
497:Atrioventricular canal
114:Anatomical terminology
37:and of the ventricles.
617:Common cardinal veins
226:Clinical significance
487:Endocardial cushions
240:extracellular matrix
203:endocardial cushions
453:Primitive ventricle
416:Development of the
244:tetralogy of Fallot
194:is in front of the
178:are divided by the
146:and fuses with the
761:Vitelline arteries
725:Inferior vena cava
492:Septum intermedium
443:Truncus arteriosus
418:circulatory system
188:truncus arteriosus
172:truncus arteriosus
166:In the developing
144:pulmonary arteries
769:
768:
737:Ductus arteriosus
705:Fetal circulation
659:
658:
558:
557:
478:Atrioventricular
472:Chamber formation
323:(4061): 1059–61.
256:tricuspid atresia
156:heart development
128:
127:
123:
16:Anatomical entity
821:
786:
785:
777:
745:Umbilical artery
733:Pulmonary artery
685:Connecting stalk
567:
566:
512:Foramen secundum
458:Primitive atrium
431:
430:
410:
403:
396:
387:
386:
368:
367:
347:
341:
340:
312:
286:
285:
215:pulmonary artery
207:semilunar valves
192:pulmonary artery
120:edit on Wikidata
117:
47:
31:
19:
18:
829:
828:
824:
823:
822:
820:
819:
818:
809:Cardiac anatomy
794:
793:
792:
780:
772:
770:
765:
756:Vitelline veins
699:
667:hemangiogenesis
665:
655:
639:
621:
593:
554:
533:
522:Septum secundum
467:
420:
414:
377:
372:
371:
348:
344:
313:
309:
283:
280:
268:
228:
164:
124:
54:
38:
17:
12:
11:
5:
827:
817:
816:
811:
806:
791:
790:
767:
766:
764:
763:
758:
748:
747:
721:Ductus venosus
717:Umbilical vein
713:umbilical cord
709:
707:
701:
700:
698:
697:
692:
687:
682:
677:
671:
669:
664:Extraembryonic
661:
660:
657:
656:
654:
653:
647:
645:
641:
640:
638:
637:
631:
629:
623:
622:
620:
619:
614:
609:
603:
601:
595:
594:
592:
591:
586:
581:
575:
573:
564:
560:
559:
556:
555:
553:
552:
547:
541:
539:
535:
534:
532:
531:
530:
529:
524:
519:
514:
509:
501:
500:
499:
494:
489:
484:
475:
473:
469:
468:
466:
465:
460:
455:
450:
445:
439:
437:
428:
422:
421:
413:
412:
405:
398:
390:
384:
383:
376:
375:External links
373:
370:
369:
358:(8): 1607–16.
342:
306:
305:
299:Gray's Anatomy
279:
276:
275:
274:
267:
264:
227:
224:
223:
222:
210:
199:
163:
160:
126:
125:
116:
110:
109:
104:
98:
97:
92:
86:
85:
81:
80:
75:
69:
68:
65:
61:
60:
56:
55:
48:
40:
39:
32:
24:
23:
15:
9:
6:
4:
3:
2:
826:
815:
812:
810:
807:
805:
802:
801:
799:
789:
784:
779:
778:
775:
762:
759:
757:
753:
750:
749:
746:
742:
738:
734:
730:
726:
722:
718:
714:
711:
710:
708:
706:
702:
696:
693:
691:
688:
686:
683:
681:
678:
676:
675:Blood islands
673:
672:
670:
668:
662:
652:
649:
648:
646:
642:
636:
633:
632:
630:
628:
627:Lymph vessels
624:
618:
615:
613:
610:
608:
605:
604:
602:
600:
596:
590:
587:
585:
584:Aortic arches
582:
580:
577:
576:
574:
572:
568:
565:
561:
551:
548:
546:
543:
542:
540:
536:
528:
527:Foramen ovale
525:
523:
520:
518:
515:
513:
510:
508:
507:Septum primum
505:
504:
502:
498:
495:
493:
490:
488:
485:
483:
480:
479:
477:
476:
474:
470:
464:
463:Sinus venosus
461:
459:
456:
454:
451:
449:
448:Bulbus cordis
446:
444:
441:
440:
438:
436:
435:Tubular heart
432:
429:
427:
423:
419:
411:
406:
404:
399:
397:
392:
391:
388:
382:
379:
378:
365:
361:
357:
353:
346:
338:
334:
330:
326:
322:
318:
311:
307:
304:
303:
300:
297:
295:
291:
290:public domain
273:
270:
269:
263:
261:
257:
253:
249:
245:
241:
237:
233:
220:
219:aortic arches
216:
211:
208:
204:
200:
197:
193:
189:
185:
184:
183:
181:
180:aortic septum
177:
176:bulbus cordis
173:
169:
159:
157:
153:
149:
145:
141:
137:
133:
121:
115:
111:
108:
105:
103:
99:
96:
93:
91:
87:
82:
79:
76:
74:
70:
66:
62:
57:
52:
46:
41:
36:
30:
25:
20:
579:Dorsal aorta
544:
355:
351:
345:
320:
316:
310:
301:
287:
281:
229:
179:
165:
136:neural crest
131:
129:
94:
78:neural crest
352:Development
236:hemodynamic
232:contractile
150:within the
84:Identifiers
51:aortic bulb
35:aortic bulb
798:Categories
635:Lymph sacs
589:Aortic sac
278:References
162:Structure
73:Precursor
752:yolk sac
695:Placenta
690:Yolk sac
571:Arteries
364:10725237
294:page 514
266:See also
788:Anatomy
680:Chorion
563:Vessels
503:Atrial
337:6844926
317:Science
154:during
59:Details
774:Portal
362:
335:
302:(1918)
258:, and
238:, and
170:, the
741:Aorta
729:Heart
644:Other
599:Veins
538:Other
426:Heart
292:from
201:Four
196:aorta
168:heart
152:heart
140:aorta
118:[
90:Latin
360:PMID
333:PMID
174:and
142:and
130:The
64:Days
356:127
325:doi
321:220
800::
754::
743:→
739:→
735:→
731:→
727:→
723:→
719:→
715::
354:.
331:.
319:.
262:.
254:,
250:,
246:,
234:,
158:.
102:TE
67:37
776::
409:e
402:t
395:v
366:.
339:.
327::
198:.
122:]
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
