2655:
1669:
2675:
1690:
2665:
36:
2701:
171:, which only reduces pain, likely explaining why it has minimal effect on inflammation; paracetamol is sometimes combined with an NSAID (in place of an opioid) in clinical practice to enhance the pain relief of the NSAID, while still receiving the injury/disease modulating effect of NSAID-induced inflammation reduction (which is not received from opioid/paracetamol combinations).
187:, resulting in death. The risk of death as a result of GI bleeding caused by the use of NSAIDs is 1 in 12,000 for adults aged 16–45. The risk increases almost twentyfold for those over 75. Other dangers of NSAIDs are exacerbating asthma and causing kidney damage. Apart from aspirin, prescription and over-the-counter NSAIDs also increase the risk of
325:
Ottani, Alessandra; Leone, Sheila; Sandrini, Maurizio; Ferrari, Anna; Bertolini, Alfio (February 15, 2006). "The analgesic activity of paracetamol is prevented by the blockade of cannabinoid CB1 receptors".
369:
Dani, Mélina; Guindon, Josée; Lambert, Chantal; Beaulieu, Pierre (November 14, 2007). "The local antinociceptive effects of paracetamol in neuropathic pain are mediated by cannabinoid receptors".
167:
in the U.S). Contrary to NSAIDs, which reduce pain and inflammation by inhibiting COX enzymes, paracetamol has—as early as 2006—been shown to block the reuptake of
137:, creating inflammation. In whole, the NSAIDs prevent the prostaglandins from ever being synthesized, reducing or eliminating the inflammation and resulting pain.
488:
Trelle, Sven; Reichenbach, Stephan; Wandel, Simon; Hildebrand, Pius; Tschannen, Beatrice; Villiger, Peter M.; Egger, Matthias; JĂĽni, Peter (11 January 2011).
57:
2658:
1621:
701:
1727:
458:
152:. The newer specific COX-inhibitors are not classified together with the traditional NSAIDs, even though they presumably share the same mode of action.
669:
2075:
1678:
282:
Knights KM, Mangoni AA, Miners JO (November 2010). "Defining the COX inhibitor selectivity of NSAIDs: implications for understanding toxicity".
622:
2374:
2150:
691:
2090:
2050:
1705:
1472:
1432:
44:
2668:
1720:
2633:
1045:
238:
1736:
1332:
1325:
2314:
1713:
126:
121:
1075:
938:
2721:
699:
159:
that are commonly associated with anti-inflammatory drugs but that have no anti-inflammatory effects. An example is
406:"Combined acetaminophen and ibuprofen for pain relief after oral surgery in adults: a randomized controlled trial"
1228:
684:
466:
249:. They are also being investigated for use in diseases and injuries involving inflammation of the brain (e.g.,
226:
17:
648:
233:
benefits, they are widely utilized in the treatment of diseases related to inflammation of the lungs, such as
927:
709:
1538:
218:
1735:
586:
Scott JP, Peters-Golden M (September 2013). "Antileukotriene agents for the treatment of lung disease".
229:), and consequently oppose the function of these inflammatory mediators. Although they are not used for
2691:
1188:
677:
2612:
2637:
1243:
921:
772:
49:
1280:
1035:
250:
109:
2617:
2607:
2602:
2592:
965:
901:
746:
188:
2587:
2564:
2045:
1917:
1040:
1020:
889:
404:
Merry AF, Gibbs RD, Edwards J, Ting GS, Frampton C, Davies E, Anderson BJ (January 2010).
8:
2641:
2597:
2514:
1892:
1649:
1385:
1171:
950:
777:
222:
2504:
2437:
1683:
1548:
1407:
861:
563:
538:
514:
490:"Cardiovascular safety of non-steroidal anti-inflammatory drugs: network meta-analysis"
489:
487:
430:
405:
307:
89:
2674:
2534:
2384:
1947:
1922:
1689:
1644:
1427:
1417:
1150:
1106:
1090:
894:
884:
827:
817:
603:
568:
519:
435:
386:
351:
311:
299:
246:
242:
2298:
1654:
1477:
1402:
1390:
1315:
1181:
1060:
849:
595:
558:
550:
509:
501:
425:
417:
378:
343:
335:
291:
214:
168:
1121:
368:
324:
2705:
2678:
2416:
2406:
2364:
1830:
1748:
1694:
1639:
1508:
1503:
1342:
1275:
1270:
1156:
1102:
943:
834:
787:
382:
339:
204:
1744:
1740:
2390:
2165:
2030:
1942:
1867:
1852:
1847:
1841:
1770:
1673:
1573:
1568:
1422:
1412:
1362:
1347:
1337:
1238:
1233:
1223:
1161:
1133:
1085:
1080:
812:
767:
763:
599:
262:
180:
134:
130:
2715:
2524:
2401:
2214:
2199:
2080:
2015:
1605:
1578:
1437:
1255:
1166:
1146:
1142:
1005:
933:
822:
737:
554:
164:
2396:
2359:
2344:
2288:
2273:
2268:
2219:
2194:
2184:
2179:
1937:
1815:
1795:
1790:
1780:
1762:
1563:
1482:
1218:
1176:
1010:
1000:
916:
911:
607:
572:
523:
439:
390:
355:
303:
85:
2632:
indicates initially developed first-in-class compound of specific group;
2529:
2509:
2478:
2463:
2354:
2319:
2308:
2118:
2040:
1968:
1957:
1907:
1902:
1447:
1357:
1097:
1050:
995:
878:
844:
421:
210:
184:
160:
347:
2559:
2549:
2544:
2539:
2488:
2453:
2303:
2251:
2246:
2241:
2236:
2209:
2133:
2070:
2009:
2003:
1978:
1973:
1912:
1897:
1887:
1857:
1825:
1810:
1757:
1625:
1596:
1554:
1523:
1518:
1457:
1452:
1442:
1380:
1366:
1306:
1261:
1209:
1129:
1125:
1066:
1026:
981:
977:
867:
803:
753:
718:
714:
295:
101:
505:
2554:
2519:
2483:
2473:
2468:
2458:
2448:
2443:
2432:
2426:
2379:
2293:
2278:
2263:
2231:
2225:
2189:
2155:
2144:
2138:
2100:
2065:
2060:
2055:
2035:
1998:
1993:
1927:
1882:
1835:
1800:
1785:
1533:
1513:
1487:
1462:
1397:
1375:
1203:
1116:
990:
230:
179:
Long-term use of NSAIDs can cause gastric erosions, which can become
156:
145:
2369:
2349:
2335:
2283:
2257:
2204:
2128:
2123:
2095:
2085:
2025:
2020:
1988:
1820:
1805:
1775:
1634:
1498:
1494:
1467:
906:
839:
758:
149:
2569:
2170:
1983:
1932:
1876:
1610:
1528:
1193:
960:
782:
732:
623:"Old rat brains rejuvenated and new neurons grown by asthma drug"
141:
105:
104:. These drugs remedy pain by reducing inflammation as opposed to
209:
Antileukotrienes are anti-inflammatory agents which function as
35:
2110:
1292:
955:
234:
192:
1592:
1302:
797:
1296:
93:
84:
is the property of a substance or treatment that reduces
115:
2689:
702:
536:
403:
281:
649:"Asthma drug found to rejuvenate older rat brains"
585:
539:"Glucocorticosteroids in football: use and misuse"
133:(COX) enzyme. On its own, COX enzyme synthesizes
27:Substance that reduces or suppresses inflammation
2713:
494:British Medical Journal (Clinical Research Ed.)
579:
1721:
685:
537:Dvorak J, Feddermann N, Grimm K (July 2006).
129:(NSAIDs) alleviate pain by counteracting the
700:Major chemical drug groups – based upon the
530:
453:
451:
449:
397:
275:
1728:
1714:
692:
678:
562:
513:
429:
620:
446:
60:of all important aspects of the article.
14:
2714:
1679:Pharmacological classification systems
1046:Selective estrogen receptor modulators
481:
183:and in extreme cases can cause severe
112:to block pain signaling to the brain.
56:Please consider expanding the lead to
1737:Non-steroidal anti-inflammatory drugs
1709:
1326:Non-steroidal anti-inflammatory drugs
673:
621:Hamzelou, Jessica (23 October 2015).
2664:
127:Nonsteroidal anti-inflammatory drugs
116:Nonsteroidal anti-inflammatory drugs
29:
2315:COX-inhibiting nitric oxide donator
939:Angiotensin II receptor antagonists
198:
140:Some common examples of NSAIDs are
122:Nonsteroidal anti-inflammatory drug
24:
543:British Journal of Sports Medicine
25:
2733:
646:
2699:
2673:
2663:
2654:
2653:
1688:
1668:
1667:
371:European Journal of Pharmacology
328:European Journal of Pharmacology
34:
2565:Superoxide dismutase / orgotein
1076:Hypothalamic–pituitary hormones
640:
227:cysteinyl leukotriene receptors
174:
48:may be too short to adequately
1877:Aspirin (acetylsalicylic acid)
614:
410:British Journal of Anaesthesia
362:
318:
58:provide an accessible overview
13:
1:
828:Thrombolytics / fibrinolytics
588:Am. J. Respir. Crit. Care Med
268:
155:On the other hand, there are
1539:Wakefulness-promoting agents
383:10.1016/j.ejphar.2007.07.012
340:10.1016/j.ejphar.2005.12.015
7:
1943:Salicylic acid (salicylate)
465:. Bandolier. Archived from
256:
219:arachidonate 5-lipoxygenase
10:
2738:
1189:Intravenous immunoglobulin
600:10.1164/rccm.201301-0023PP
463:NSAIDs and adverse effects
202:
119:
2649:
2626:
2578:
2497:
2415:
2328:
2164:
2109:
1956:
1866:
1756:
1663:
1619:
1591:
1547:
1356:
1291:
1254:
1202:
1115:
1059:
1019:
976:
860:
796:
708:
284:Expert Rev Clin Pharmacol
2722:Anti-inflammatory agents
2613:Naproxen/diphenhydramine
1244:Topoisomerase inhibitors
928:renin–angiotensin system
922:Calcium channel blockers
555:10.1136/bjsm.2006.027599
100:, make up about half of
2634:WHO-Essential Medicines
1962:and related substances
1036:Hormonal contraception
966:Bile acid sequestrants
747:Proton-pump inhibitors
710:gastrointestinal tract
110:central nervous system
2618:Naproxen/esomeprazole
2608:Meloxicam/bupivacaine
2603:Ibuprofen/paracetamol
2593:Ibuprofen/hydrocodone
2588:Ibuprofen/famotidine
2046:Indometacin farnesil
1918:Magnesium salicylate
1739:(NSAIDs) (primarily
1645:Radiopharmaceuticals
1433:Antiparkinson agents
469:on February 18, 2012
223:receptor antagonists
92:. Anti-inflammatory
2598:Ibuprofen/oxycodone
2515:Chondroitin sulfate
1893:Carbasalate calcium
1428:Antimigraine agents
1418:Antidementia agents
1321:Anti-inflammatories
1011:Medicated dressings
951:Antihyperlipidemics
778:Diabetes medication
549:(Suppl 1): i48–54.
251:Parkinson's disease
108:, which affect the
98:anti-inflammatories
2505:Aminopropionitrile
1281:Immunosuppressants
1151:Antimycobacterials
1107:Antithyroid agents
1091:Mineralocorticoids
895:Cardiac stimulants
885:Cardiac glycosides
877:cardiac therapy /
773:Anti-obesity drugs
422:10.1093/bja/aep338
296:10.1586/ecp.10.120
2687:
2686:
2535:Glycosaminoglycan
2385:Meclofenamic acid
1948:Sodium salicylate
1923:Methyl salicylate
1703:
1702:
1606:Ophthalmologicals
1316:Anabolic steroids
1219:Anticancer agents
1182:Ectoparasiticides
902:Antihypertensives
850:Antifibrinolytics
653:medicalxpress.com
506:10.1136/bmj.c7086
247:allergic rhinitis
221:) or leukotriene
215:enzyme inhibitors
78:Anti-inflammatory
75:
74:
16:(Redirected from
2729:
2704:
2703:
2702:
2695:
2677:
2667:
2666:
2657:
2656:
2417:COX-2 inhibitors
2332:-arylanthranilic
2299:Tiaprofenic acid
1730:
1723:
1716:
1707:
1706:
1692:
1671:
1670:
1655:Senotherapeutics
1509:Neuroprotectives
1504:Mood stabilizers
1403:Anti-ADHD agents
1343:Muscle relaxants
1276:Immunostimulants
1271:Immunomodulators
1103:Thyroid hormones
1041:Fertility agents
944:Renin inhibitors
835:Antihemorrhagics
802:forming organs (
788:Dietary minerals
694:
687:
680:
671:
670:
664:
663:
661:
659:
644:
638:
637:
635:
633:
618:
612:
611:
583:
577:
576:
566:
534:
528:
527:
517:
485:
479:
478:
476:
474:
455:
444:
443:
433:
401:
395:
394:
377:(1–3): 214–215.
366:
360:
359:
334:(1–3): 280–281.
322:
316:
315:
279:
245:inflammation in
199:Antileukotrienes
169:endocannabinoids
70:
67:
61:
38:
30:
21:
2737:
2736:
2732:
2731:
2730:
2728:
2727:
2726:
2712:
2711:
2710:
2700:
2698:
2690:
2688:
2683:
2645:
2638:withdrawn drugs
2622:
2580:
2574:
2493:
2419:
2411:
2407:Tolfenamic acid
2365:Flufenamic acid
2333:
2324:
2168:
2160:
2105:
1961:
1952:
1862:
1831:Oxyphenbutazone
1761:
1752:
1734:
1704:
1699:
1695:Medicine portal
1659:
1615:
1587:
1582:
1574:Cough medicines
1569:Bronchodilators
1550:
1543:
1423:Antidepressants
1413:Anticonvulsants
1361:
1352:
1348:Bisphosphonates
1338:Corticosteroids
1300:
1287:
1259:
1250:
1234:Spindle poisons
1224:Antimetabolites
1207:
1198:
1120:
1111:
1086:Glucocorticoids
1081:Corticosteroids
1062:
1055:
1022:
1015:
972:
890:Antiarrhythmics
863:
856:
813:Antithrombotics
801:
792:
768:Antipropulsives
764:Antidiarrhoeals
741:
712:
704:
698:
668:
667:
657:
655:
645:
641:
631:
629:
619:
615:
584:
580:
535:
531:
486:
482:
472:
470:
457:
456:
447:
402:
398:
367:
363:
323:
319:
280:
276:
271:
259:
207:
205:Antileukotriene
201:
177:
124:
118:
71:
65:
62:
55:
43:This article's
39:
28:
23:
22:
15:
12:
11:
5:
2735:
2725:
2724:
2709:
2708:
2685:
2684:
2682:
2681:
2671:
2661:
2650:
2647:
2646:
2642:veterinary use
2627:
2624:
2623:
2621:
2620:
2615:
2610:
2605:
2600:
2595:
2590:
2584:
2582:
2576:
2575:
2573:
2572:
2567:
2562:
2557:
2552:
2547:
2542:
2537:
2532:
2527:
2522:
2517:
2512:
2507:
2501:
2499:
2495:
2494:
2492:
2491:
2486:
2481:
2476:
2471:
2466:
2461:
2456:
2451:
2446:
2441:
2429:
2423:
2421:
2413:
2412:
2410:
2409:
2404:
2399:
2394:
2391:Mefenamic acid
2387:
2382:
2377:
2372:
2367:
2362:
2357:
2352:
2347:
2341:
2339:
2326:
2325:
2323:
2322:
2311:
2306:
2301:
2296:
2291:
2286:
2281:
2276:
2271:
2266:
2261:
2254:
2249:
2244:
2239:
2234:
2229:
2222:
2217:
2212:
2207:
2202:
2197:
2192:
2187:
2182:
2176:
2174:
2166:propionic acid
2162:
2161:
2159:
2158:
2153:
2148:
2141:
2136:
2131:
2126:
2121:
2115:
2113:
2107:
2106:
2104:
2103:
2098:
2093:
2088:
2083:
2078:
2073:
2068:
2063:
2058:
2053:
2048:
2043:
2038:
2033:
2031:Fenclozic acid
2028:
2023:
2018:
2013:
2006:
2001:
1996:
1991:
1986:
1981:
1976:
1971:
1965:
1963:
1954:
1953:
1951:
1950:
1945:
1940:
1935:
1930:
1925:
1920:
1915:
1910:
1905:
1900:
1895:
1890:
1885:
1880:
1872:
1870:
1864:
1863:
1861:
1860:
1855:
1853:Sulfinpyrazone
1850:
1848:Propyphenazone
1845:
1842:Phenylbutazone
1838:
1833:
1828:
1823:
1818:
1813:
1808:
1803:
1798:
1793:
1788:
1783:
1778:
1773:
1771:Aminophenazone
1767:
1765:
1754:
1753:
1733:
1732:
1725:
1718:
1710:
1701:
1700:
1698:
1697:
1686:
1681:
1676:
1664:
1661:
1660:
1658:
1657:
1652:
1647:
1642:
1640:Contrast media
1637:
1631:
1629:
1617:
1616:
1614:
1613:
1608:
1602:
1600:
1593:sensory organs
1589:
1588:
1586:
1585:
1580:
1576:
1571:
1566:
1560:
1558:
1545:
1544:
1542:
1541:
1536:
1531:
1526:
1521:
1516:
1511:
1506:
1501:
1492:
1491:
1490:
1485:
1480:
1470:
1465:
1460:
1455:
1450:
1445:
1440:
1438:Antipsychotics
1435:
1430:
1425:
1420:
1415:
1410:
1408:Antiaddictives
1405:
1400:
1395:
1394:
1393:
1388:
1378:
1372:
1370:
1363:nervous system
1354:
1353:
1351:
1350:
1345:
1340:
1335:
1333:Antirheumatics
1330:
1329:
1328:
1318:
1312:
1310:
1289:
1288:
1286:
1285:
1284:
1283:
1278:
1267:
1265:
1252:
1251:
1249:
1248:
1247:
1246:
1241:
1239:Antineoplastic
1236:
1231:
1226:
1215:
1213:
1200:
1199:
1197:
1196:
1191:
1186:
1185:
1184:
1179:
1174:
1172:Antiprotozoals
1167:Antiparasitics
1164:
1159:
1154:
1147:Antibacterials
1143:Antimicrobials
1139:
1137:
1113:
1112:
1110:
1109:
1100:
1095:
1094:
1093:
1088:
1078:
1072:
1070:
1057:
1056:
1054:
1053:
1048:
1043:
1038:
1032:
1030:
1017:
1016:
1014:
1013:
1008:
1006:Antipsoriatics
1003:
998:
993:
987:
985:
974:
973:
971:
970:
969:
968:
963:
958:
948:
947:
946:
941:
936:
934:ACE inhibitors
924:
919:
914:
909:
904:
899:
898:
897:
892:
887:
873:
871:
862:cardiovascular
858:
857:
855:
854:
853:
852:
847:
842:
832:
831:
830:
825:
823:Anticoagulants
820:
809:
807:
794:
793:
791:
790:
785:
780:
775:
770:
761:
756:
751:
750:
749:
744:
739:
735:
724:
722:
706:
705:
697:
696:
689:
682:
674:
666:
665:
639:
613:
594:(5): 538–544.
578:
529:
480:
445:
396:
361:
317:
273:
272:
270:
267:
266:
265:
263:Corticosteroid
258:
255:
203:Main article:
200:
197:
181:stomach ulcers
176:
173:
135:prostaglandins
131:cyclooxygenase
120:Main article:
117:
114:
96:, also called
82:antiphlogistic
73:
72:
52:the key points
42:
40:
33:
26:
18:Antiphlogistic
9:
6:
4:
3:
2:
2734:
2723:
2720:
2719:
2717:
2707:
2697:
2696:
2693:
2680:
2676:
2672:
2670:
2662:
2660:
2652:
2651:
2648:
2643:
2639:
2635:
2631:
2625:
2619:
2616:
2614:
2611:
2609:
2606:
2604:
2601:
2599:
2596:
2594:
2591:
2589:
2586:
2585:
2583:
2577:
2571:
2568:
2566:
2563:
2561:
2558:
2556:
2553:
2551:
2548:
2546:
2543:
2541:
2538:
2536:
2533:
2531:
2528:
2526:
2525:Fluproquazone
2523:
2521:
2518:
2516:
2513:
2511:
2508:
2506:
2503:
2502:
2500:
2496:
2490:
2487:
2485:
2482:
2480:
2477:
2475:
2472:
2470:
2467:
2465:
2462:
2460:
2457:
2455:
2452:
2450:
2447:
2445:
2442:
2439:
2435:
2434:
2430:
2428:
2425:
2424:
2422:
2418:
2414:
2408:
2405:
2403:
2402:Niflumic acid
2400:
2398:
2395:
2393:
2392:
2388:
2386:
2383:
2381:
2378:
2376:
2373:
2371:
2368:
2366:
2363:
2361:
2358:
2356:
2353:
2351:
2348:
2346:
2343:
2342:
2340:
2337:
2331:
2327:
2321:
2317:
2316:
2312:
2310:
2307:
2305:
2302:
2300:
2297:
2295:
2292:
2290:
2287:
2285:
2282:
2280:
2277:
2275:
2272:
2270:
2267:
2265:
2262:
2260:
2259:
2255:
2253:
2250:
2248:
2245:
2243:
2240:
2238:
2235:
2233:
2230:
2228:
2227:
2223:
2221:
2218:
2216:
2215:Flunoxaprofen
2213:
2211:
2208:
2206:
2203:
2201:
2200:Dexketoprofen
2198:
2196:
2193:
2191:
2188:
2186:
2183:
2181:
2178:
2177:
2175:
2172:
2169:derivatives (
2167:
2163:
2157:
2154:
2152:
2149:
2147:
2146:
2142:
2140:
2137:
2135:
2132:
2130:
2127:
2125:
2122:
2120:
2117:
2116:
2114:
2112:
2108:
2102:
2099:
2097:
2094:
2092:
2089:
2087:
2084:
2082:
2081:Proglumetacin
2079:
2077:
2076:Prodolic acid
2074:
2072:
2069:
2067:
2064:
2062:
2059:
2057:
2054:
2052:
2049:
2047:
2044:
2042:
2039:
2037:
2034:
2032:
2029:
2027:
2024:
2022:
2019:
2017:
2016:Difenpiramide
2014:
2012:
2011:
2007:
2005:
2002:
2000:
1997:
1995:
1992:
1990:
1987:
1985:
1982:
1980:
1977:
1975:
1972:
1970:
1967:
1966:
1964:
1959:
1955:
1949:
1946:
1944:
1941:
1939:
1936:
1934:
1931:
1929:
1926:
1924:
1921:
1919:
1916:
1914:
1911:
1909:
1906:
1904:
1901:
1899:
1896:
1894:
1891:
1889:
1886:
1884:
1881:
1879:
1878:
1874:
1873:
1871:
1869:
1865:
1859:
1856:
1854:
1851:
1849:
1846:
1844:
1843:
1839:
1837:
1834:
1832:
1829:
1827:
1824:
1822:
1819:
1817:
1814:
1812:
1809:
1807:
1804:
1802:
1799:
1797:
1794:
1792:
1789:
1787:
1784:
1782:
1779:
1777:
1774:
1772:
1769:
1768:
1766:
1764:
1763:pyrazolidines
1759:
1755:
1750:
1746:
1742:
1738:
1731:
1726:
1724:
1719:
1717:
1712:
1711:
1708:
1696:
1691:
1687:
1685:
1682:
1680:
1677:
1675:
1666:
1665:
1662:
1656:
1653:
1651:
1648:
1646:
1643:
1641:
1638:
1636:
1633:
1632:
1630:
1627:
1623:
1618:
1612:
1609:
1607:
1604:
1603:
1601:
1598:
1594:
1590:
1584:
1577:
1575:
1572:
1570:
1567:
1565:
1564:Decongestants
1562:
1561:
1559:
1556:
1552:
1546:
1540:
1537:
1535:
1532:
1530:
1527:
1525:
1522:
1520:
1517:
1515:
1512:
1510:
1507:
1505:
1502:
1500:
1496:
1493:
1489:
1486:
1484:
1483:Dissociatives
1481:
1479:
1476:
1475:
1474:
1473:Hallucinogens
1471:
1469:
1466:
1464:
1461:
1459:
1456:
1454:
1451:
1449:
1446:
1444:
1441:
1439:
1436:
1434:
1431:
1429:
1426:
1424:
1421:
1419:
1416:
1414:
1411:
1409:
1406:
1404:
1401:
1399:
1396:
1392:
1389:
1387:
1384:
1383:
1382:
1379:
1377:
1374:
1373:
1371:
1368:
1364:
1359:
1355:
1349:
1346:
1344:
1341:
1339:
1336:
1334:
1331:
1327:
1324:
1323:
1322:
1319:
1317:
1314:
1313:
1311:
1308:
1304:
1298:
1294:
1290:
1282:
1279:
1277:
1274:
1273:
1272:
1269:
1268:
1266:
1263:
1257:
1253:
1245:
1242:
1240:
1237:
1235:
1232:
1230:
1227:
1225:
1222:
1221:
1220:
1217:
1216:
1214:
1211:
1205:
1201:
1195:
1192:
1190:
1187:
1183:
1180:
1178:
1177:Anthelmintics
1175:
1173:
1170:
1169:
1168:
1165:
1163:
1160:
1158:
1155:
1152:
1148:
1144:
1141:
1140:
1138:
1135:
1131:
1127:
1123:
1118:
1114:
1108:
1104:
1101:
1099:
1096:
1092:
1089:
1087:
1084:
1083:
1082:
1079:
1077:
1074:
1073:
1071:
1068:
1064:
1058:
1052:
1049:
1047:
1044:
1042:
1039:
1037:
1034:
1033:
1031:
1028:
1024:
1021:genitourinary
1018:
1012:
1009:
1007:
1004:
1002:
1001:Antipruritics
999:
997:
994:
992:
989:
988:
986:
983:
979:
975:
967:
964:
962:
959:
957:
954:
953:
952:
949:
945:
942:
940:
937:
935:
932:
931:
930:
929:
925:
923:
920:
918:
917:Beta blockers
915:
913:
910:
908:
905:
903:
900:
896:
893:
891:
888:
886:
883:
882:
881:
880:
875:
874:
872:
869:
865:
859:
851:
848:
846:
843:
841:
838:
837:
836:
833:
829:
826:
824:
821:
819:
818:Antiplatelets
816:
815:
814:
811:
810:
808:
805:
799:
795:
789:
786:
784:
781:
779:
776:
774:
771:
769:
765:
762:
760:
757:
755:
752:
748:
745:
743:
736:
734:
731:
730:
729:
726:
725:
723:
720:
716:
711:
707:
703:
695:
690:
688:
683:
681:
676:
675:
672:
654:
650:
643:
628:
627:New Scientist
624:
617:
609:
605:
601:
597:
593:
589:
582:
574:
570:
565:
560:
556:
552:
548:
544:
540:
533:
525:
521:
516:
511:
507:
503:
499:
495:
491:
484:
468:
464:
460:
454:
452:
450:
441:
437:
432:
427:
423:
419:
415:
411:
407:
400:
392:
388:
384:
380:
376:
372:
365:
357:
353:
349:
345:
341:
337:
333:
329:
321:
313:
309:
305:
301:
297:
293:
290:(6): 769–76.
289:
285:
278:
274:
264:
261:
260:
254:
252:
248:
244:
241:, as well as
240:
236:
232:
228:
224:
220:
216:
212:
206:
196:
194:
190:
186:
182:
172:
170:
166:
165:acetaminophen
162:
158:
153:
151:
147:
143:
138:
136:
132:
128:
123:
113:
111:
107:
103:
99:
95:
91:
87:
83:
79:
69:
59:
53:
51:
46:
41:
37:
32:
31:
19:
2629:
2581:combinations
2431:
2397:Morniflumate
2389:
2360:Floctafenine
2345:Azapropazone
2329:
2313:
2289:Tarenflurbil
2274:Piketoprofen
2269:Pelubiprofen
2256:
2224:
2220:Flurbiprofen
2195:Dexibuprofen
2185:Benoxaprofen
2180:Alminoprofen
2143:
2008:
1938:Salicylamide
1875:
1840:
1816:Mofebutazone
1796:Famprofazone
1791:Difenamizole
1781:Azapropazone
1478:Psychedelics
1448:Aphrodisiacs
1320:
1122:infestations
1098:Sex hormones
1051:Sex hormones
996:Cicatrizants
926:
912:Vasodilators
879:antianginals
876:
728:stomach acid
727:
656:. Retrieved
652:
647:Yirka, Bob.
642:
630:. Retrieved
626:
616:
591:
587:
581:
546:
542:
532:
497:
493:
483:
473:December 20,
471:. Retrieved
467:the original
462:
413:
409:
399:
374:
370:
364:
348:11380/613413
331:
327:
320:
287:
283:
277:
208:
189:heart attack
178:
175:Side effects
154:
139:
125:
97:
86:inflammation
81:
77:
76:
63:
47:
45:lead section
2530:Glucosamine
2510:Benzydamine
2479:Robenacoxib
2464:Lumiracoxib
2355:Etofenamate
2320:Naproxcinod
2309:Zaltoprofen
2119:Ampiroxicam
2041:Indometacin
1969:Aceclofenac
1960:derivatives
1958:acetic acid
1908:Ethenzamide
1903:Dipyrocetyl
1868:salicylates
1758:pyrazolones
1611:Otologicals
1583:antagonists
1549:respiratory
1524:Orexigenics
1519:Neurotoxins
1468:Euphoriants
1458:Entactogens
1453:Depressants
1443:Anxiolytics
1381:Anesthetics
1157:Antifungals
754:Antiemetics
742:antagonists
416:(1): 80–8.
211:leukotriene
185:haemorrhage
161:paracetamol
2560:Proquazone
2550:Nimesulide
2545:Nabumetone
2540:Hyperforin
2489:Valdecoxib
2454:Etoricoxib
2304:Vedaprofen
2252:Miroprofen
2247:Loxoprofen
2242:Ketoprofen
2237:Indoprofen
2210:Fenoprofen
2134:Lornoxicam
2071:Oxametacin
2010:Diclofenac
2004:Bumadizone
1979:Alclofenac
1974:Acemetacin
1913:Guacetisal
1898:Diflunisal
1888:Benorylate
1858:Suxibuzone
1826:Nifenazone
1811:Metamizole
1534:Stimulants
1514:Nootropics
1488:Deliriants
1463:Entheogens
1398:Anorectics
1376:Analgesics
1229:Alkylating
1162:Antivirals
1117:infections
991:Emollients
845:Coagulants
715:metabolism
658:3 November
632:28 October
269:References
163:(known as
157:analgesics
102:analgesics
66:March 2024
2630:underline
2555:Oxaceprol
2520:Diacerein
2484:Rofecoxib
2474:Parecoxib
2469:Mavacoxib
2459:Firocoxib
2449:Deracoxib
2444:Cimicoxib
2438:+tramadol
2433:Celecoxib
2427:Apricoxib
2380:Glafenine
2375:Flutiazin
2336:fenamates
2294:Tepoxalin
2279:Pirprofen
2264:Oxaprozin
2232:Ibuproxam
2226:Ibuprofen
2190:Carprofen
2156:Tenoxicam
2151:Pivoxicam
2145:Piroxicam
2139:Meloxicam
2101:Zomepirac
2066:Mofezolac
2061:Lonazolac
2056:Ketorolac
2036:Fentiazac
1999:Bufexamac
1994:Bromfenac
1928:Salsalate
1883:Aloxiprin
1836:Phenazone
1801:Feprazone
1786:Clofezone
1684:ATC codes
1650:Dressings
1635:Antidotes
1499:Sedatives
1495:Hypnotics
1204:malignant
1061:endocrine
907:Diuretics
840:Platelets
800:and blood
759:Laxatives
500:: c7086.
459:"Table 7"
312:207209534
231:analgesic
213:-related
146:ibuprofen
50:summarize
2716:Category
2706:Medicine
2659:category
2420:(coxibs)
2370:Flunixin
2350:Clonixin
2284:Suprofen
2258:Naproxen
2205:Fenbufen
2129:Isoxicam
2124:Droxicam
2096:Tolmetin
2091:Tiopinac
2086:Sulindac
2051:Isoxepac
2026:Felbinac
2021:Etodolac
1989:Bendazac
1821:Morazone
1806:Kebuzone
1776:Ampyrone
1529:Serenics
1194:Vaccines
961:Fibrates
783:Vitamins
733:Antacids
608:23822826
573:16799104
524:21224324
440:20007794
391:17651722
356:16438952
304:22111779
257:See also
150:naproxen
90:swelling
2669:commons
2570:Tenidap
2334:acids (
2171:profens
2111:oxicams
1984:Amfenac
1933:Salicin
1747:, also
1386:General
1293:muscles
1262:L03–L04
1258:disease
1210:L01–L02
1206:disease
956:Statins
564:2657490
515:3019238
431:2791549
142:aspirin
106:opioids
2692:Portal
2679:portal
1693:
1672:
1620:other
1551:system
1303:joints
1256:immune
1063:system
1023:system
864:system
606:
571:
561:
522:
512:
438:
428:
389:
354:
310:
302:
235:asthma
193:stroke
148:, and
2628:Key:
2579:NSAID
2498:other
1749:N02BA
1674:Drugs
1391:Local
1358:brain
1297:bones
798:blood
308:S2CID
243:sinus
94:drugs
1745:M02A
1743:and
1741:M01A
1301:and
978:skin
660:2015
634:2015
604:PMID
569:PMID
520:PMID
475:2012
436:PMID
387:PMID
352:PMID
300:PMID
239:COPD
237:and
191:and
1622:ATC
1360:and
1119:and
596:doi
592:188
559:PMC
551:doi
510:PMC
502:doi
498:342
426:PMC
418:doi
414:104
379:doi
375:573
344:hdl
336:doi
332:531
292:doi
253:).
88:or
80:or
2718::
2640:;
2636:;
2318::
1497:/
1295:,
1145::
1134:QI
1132:,
1128:,
1105:/
766:/
713:/
651:.
625:.
602:.
590:.
567:.
557:.
547:40
545:.
541:.
518:.
508:.
496:.
492:.
461:.
448:^
434:.
424:.
412:.
408:.
385:.
373:.
350:.
342:.
330:.
306:.
298:.
286:.
195:.
144:,
2694::
2644:.
2440:)
2436:(
2338:)
2330:n
2173:)
1760:/
1751:)
1729:e
1722:t
1715:v
1628:)
1626:V
1624:(
1599:)
1597:S
1595:(
1581:1
1579:H
1557:)
1555:R
1553:(
1369:)
1367:N
1365:(
1309:)
1307:M
1305:(
1299:,
1264:)
1260:(
1212:)
1208:(
1153:)
1149:(
1136:)
1130:P
1126:J
1124:(
1069:)
1067:H
1065:(
1029:)
1027:G
1025:(
984:)
982:D
980:(
870:)
868:C
866:(
806:)
804:B
740:2
738:H
721:)
719:A
717:(
693:e
686:t
679:v
662:.
636:.
610:.
598::
575:.
553::
526:.
504::
477:.
442:.
420::
393:.
381::
358:.
346::
338::
314:.
294::
288:3
225:(
217:(
68:)
64:(
54:.
20:)
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.