1740:, monitoring one's own symptoms, goal setting and action planning. It also includes patient-physician shared decision-making, among others. The benefits of self-management vary depending on self-management techniques used. They only have marginal benefits in management of chronic musculoskeletal pain. Some research has shown that self-management of pain can use different approaches. Those approaches can range from different therapies such as yoga, acupuncture, exercise and other relaxation techniques. Patients could also take a more natural approach by taking different minerals, vitamins or herbs. However, research has shown there is a difference between rural patients and non-rural patients having more access to different self-management approaches. Physicians in these areas may be readily prescribing more pain medication in these rural cities due to being less experienced with pain management. Simply put, it is sometimes easier for rural patients to get a prescription that insurance pays for instead of natural approaches that cost more money than they can afford to spend on their pain management. Self-management may be a more expensive alternative.
487:, promote harmony of the mind and body through total body awareness. These practices incorporate breathing techniques, meditation and a wide variety of movements, while training the body to perform functionally by increasing strength, flexibility, and range of motion. Physical activity can also benefit chronic sufferers by reducing inflammation and sensitivity, and boosting overall energy. Physical activity and exercise may improve chronic pain (pain lasting more than 12 weeks), and overall quality of life, while minimizing the need for pain medications. More specifically, walking has been effective in improving pain management in chronic low back pain.
531:
excitability of large cortical areas. tDCS may have a role in pain assessment by contributing to efforts in distinguishing between somatic and affective aspects of pain experience. Zaghi and colleagues (2011) found that the motor cortex, when stimulated with tDCS, increases the threshold for both the perception of non-painful and painful stimuli. Although there is a greater need for research examining the mechanism of electrical stimulation in relation to pain treatment, one theory suggests that the changes in thalamic activity may be due the influence of motor cortex stimulation on the decrease in pain sensations.
749:
experiential behavior change methods. The central process in ACT revolves around psychological flexibility, which in turn includes processes of acceptance, awareness, a present-oriented quality in interacting with experiences, an ability to persist or change behavior, and an ability to be guided by one's values. ACT has an increased evidence base for range of health and behavior problems, including chronic pain. ACT influences patients to adopt a tandem process to acceptance and change, which allows for a greater flexibility in the focus of treatment.
915:. However it can be used by medical professionals as a general principle when managing any type of pain. In the treatment of chronic pain, the three-step WHO Analgesic Ladder provides guidelines for selecting the appropriate medicine. The exact medications recommended will vary by country and the individual treatment center, but the following gives an example of the WHO approach to treating chronic pain with medications. If, at any point, treatment fails to provide adequate pain relief, then the doctor and patient move onto the next step.
468:
1875:
measure of pain. Self-report pain scales involve younger kids matching their pain intensity to photographs of other children's faces, such as the Oucher Scale, pointing to schematics of faces showing different pain levels, or pointing out the location of pain on a body outline. Questionnaires for older children and adolescents include the Varni-Thompson
Pediatric Pain Questionnaire (PPQ) and the Children's Comprehensive Pain Questionnaire. They are often utilized for individuals with chronic or persistent pain.
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depression, and the use of psychotropic medications. Physicians who prescribe opioids should integrate this treatment with any psychotherapeutic intervention the patient may be receiving. The guidelines also recommend monitoring not only the pain but also the level of functioning and the achievement of therapeutic goals. The prescribing physician should be suspicious of abuse when a patient reports a reduction in pain but has no accompanying improvement in function or progress in achieving identified goals.
502:
autoimmune neurological disorder, which consists of the demyelination of the nerve axons and disruption of nerve conduction velocity and efficiency. In one study, electrodes were placed over the lumbar spine and participants received treatment twice a day and at any time when they experienced a painful episode. This study found that TENS would be beneficial to MS patients who reported localized or limited symptoms to one limb. The research is mixed with whether or not TENS helps manage pain in MS patients.
772:
fibromyalgia. Evidence for the usefulness of CBT in the management of adult chronic pain is generally poorly understood, due partly to the proliferation of techniques of doubtful quality, and the poor quality of reporting in clinical trials. The crucial content of individual interventions has not been isolated and the important contextual elements, such as therapist training and development of treatment manuals, have not been determined. The widely varying nature of the resulting data makes useful
1863:
155:
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with each other about how pain responds to treatments. There is a risk in many types of pain management for the patient to take treatment that is less effective than needed or which causes other difficulties and side effects. Some treatments for pain can be harmful if overused. A goal of pain management for the patient and their health care provider is to identify the amount of treatment needed to address the pain without going beyond that limit.
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144:
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597:, energy created from light, from these photochemical reactions provide the reactants with energy provide the reactants with energy to embed in muscles, thus managing pain. One study conducted by Stausholm et al. showed that at certain wavelengths, LLLT reduced pain in participants with knee osteoarthritis. LLLT stimulates a variety oof cell types, which in turn can help treat tendonitis, arthritis, and pain relating to muscles.
554:
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298:, however, frequently requires the coordinated efforts of the pain management team. Effective pain management does not always mean total eradication of all pain. Rather, it often means achieving adequate quality of life in the presence of pain, through any combination of lessening the pain and/or better understanding it and being able to live happily despite it. Medicine treats
434:, as well as therapeutic exercises and behavioral therapy. These techniques are usually part of an interdisciplinary or multidisciplinary program that might also include pharmaceutical medicines. Spa therapy has showed positive effects in reducing pain among patients with chronic low back pain. However, there are limited studies looking at this approach. Studies have shown that
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mindfulness were also observed in a study applying ACT to chronic pain in older adults. In addition, these primary results suggested that an ACT based treatment may significantly improve levels of physical disability, psychosocial disability, and depression post-treatment and at a three-month follow-up for older adults with chronic pain.
795:(BT) is effective for reducing this type of pain, however BT may be useful for improving a person's mood immediately after treatment. This improvement appears to be small, and is short term in duration. CBT may have a small positive short-term effect on pain immediately following treatment. CBT may also have a small effect on reducing
808:
maintained for at least three months following the therapy. Psychological treatments may also improve pain control for children or adolescents who experience pain not related to headaches. It is not known if psychological therapy improves a child or adolescents mood and the potential for disability related to their chronic pain.
1415:, studies have shown that properly managed medical use of opioid analgesic compounds (taken exactly as prescribed) is safe, can manage pain effectively, and rarely causes addiction." In 2013, the FDA stated that "abuse and misuse of these products have created a serious and growing public health problem".
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recommend. Some studies about gender biases have concluded that female pain recipients are often overlooked when it comes to the perception of their pain. Whether they appeared to be in high levels of pain didn't make a difference for their observers. The women participants in the studies were still
1658:, various studies were cited in demonstrating that cannabinoids exhibit comparable effectiveness to opioids in models of acute pain and even greater effectiveness in models of chronic pain. It is mainly the THC strain of medical marijuana that provide analgesic benefits, as opposed to the CBD strain.
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which is convenient for chronic pain management. In addition to the intrathecal patch and injectable fentanyl formulations, the FDA (Food and Drug
Administration) has approved various immediate release fentanyl products for breakthrough cancer pain (Actiq/OTFC/Fentora/Onsolis/Subsys/Lazanda/Abstral).
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Boswell, Mark V.; Trescot, Andrea M.; Datta, Sukdeb; Schultz, David M.; Hansen, Hans C.; Abdi, Salahadin; Sehgal, Nalini; Shah, Rinoo V.; Singh, Vijay; Benyamin, Ramsin M.; Patel, Vikram B.; Buenaventura, Ricardo M.; Colson, James D.; Cordner, Harold J.; Epter, Richard S.; Jasper, Joseph F.; Dunbar,
538:
Fibromyalgia is a disorder in which an individual experiences dysfunctional brain activity, musculoskeletal pain, fatigue, and tenderness in localized areas. Research examining tDCS for pain treatment in fibromyalgia has found initial evidence for pain decreases. Specifically, the stimulation of the
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Transcranial direct current stimulation (tDCS) is a non-invasive technique of brain stimulation that can modulate activity in specific brain cortex regions, and it involves the application of low-intensity (up to 2 mA) constant direct current to the scalp through electrodes in order to modulate
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When treating moderate to severe pain, the type of the pain, acute or chronic, needs to be considered. The type of pain can result in different medications being prescribed. Certain medications may work better for acute pain, others for chronic pain, and some may work equally well on both. Acute
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Acceptance and
Commitment Therapy (ACT) is a form of cognitive behavioral therapy that focuses on behavior change rather than symptom change, includes methods designed to alter the context around psychological experiences rather than to alter the makeup of the experiences, and emphasizes the use of
409:
A common challenge in pain management is communication between the health care provider and the person experiencing pain. People experiencing pain may have difficulty recognizing or describing what they feel and how intense it is. Health care providers and patients may have difficulty communicating
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Caregivers may provide nonpharmacological treatment for children and adolescents because it carries minimal risk and is cost effective compared to pharmacological treatment. Nonpharmacologic interventions vary by age and developmental factors. Physical interventions to ease pain in infants include
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community has been shown to suffer significantly when it comes to trusting the medical community to treat them. Oftentimes medication although available to be prescribed is dispensed in less quantities due to their pain being perceived on a smaller scale. The black community could be undermined by
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There are other prevalent reasons that undertreatment of pain occurs. Gender is a factor as well as race. When it comes to prescribers treating patients racial disparities has become a real factor. Research has shown that non-white individuals pain perception has affected their pain treatment. The
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in the reduction of pain in some conditions. However the studies had some limitations like small study sizes, bringing up issues of power to detect group differences, and lacking credible controls for placebo or expectation. The authors concluded that "although the findings provide support for the
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Cognitive behavioral therapy (CBT) helps patients with pain to understand the relationship between their pain, thoughts, emotions, and behaviors. A main goal in treatment is cognitive (thinking, reasoning or remembering) restructuring to encourage helpful thought patterns. This will target healthy
413:
Another problem with pain management is that pain is the body's natural way of communicating a problem. Pain is supposed to resolve as the body heals itself with time and pain management. Sometimes pain management covers a problem, and the patient might be less aware that they need treatment for a
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Pain assessment in children is often challenging due to limitations in developmental level, cognitive ability, or their previous pain experiences. Clinicians must observe physiological and behavioral cues exhibited by the child to make an assessment. Self-report, if possible, is the most accurate
313:
The task of medicine is to relieve suffering under three circumstances. The first is when a painful injury or pathology is resistant to treatment and persists. The second is when pain persists after the injury or pathology has healed. Finally, the third circumstance is when medical science cannot
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organizations establish guidelines to determine the treatment for pain which health care providers ought to offer. For various social reasons, persons in pain may not seek or may not be able to access treatment for their pain. Health care providers may not provide the treatment which authorities
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to be in less pain than they actually were. Men participants on the other hand were offered pain relief while their self reporting indicated that their pain levels didn't necessarily warrant treatment. Biases exist when it comes to gender. Prescribers have been seen over and under prescribing
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Hypnosis has reduced the pain of some harmful medical procedures in children and adolescents. In clinical trials addressing other patient groups, it has significantly reduced pain compared to no treatment or some other non-hypnotic interventions. The effects of self hypnosis on chronic pain are
841:, concluded, "that MBIs decrease the intensity of pain for chronic pain patients." A 2019 review of studies of brief mindfulness-based interventions (BMBI) concluded that BMBI are not recommended as a first-line treatment and could not confirm their efficacy in managing chronic or acute pain.
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Although opioids are strong analgesics, they do not provide complete analgesia regardless of whether the pain is acute or chronic in origin. Opioids are effective analgesics in chronic malignant pain and modestly effective in nonmalignant pain management. However, there are associated adverse
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For children and adolescents, a review of RCTs evaluating the effectiveness of psychological therapy for the management of chronic and recurrent pain found that psychological treatments are effective in reducing pain when people under 18 years old have headaches. This beneficial effect may be
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Studies have demonstrated the usefulness of cognitive behavioral therapy in the management of chronic low back pain, producing significant decreases in physical and psychosocial disability. CBT is significantly more effective than standard care in treatment of people with body-wide pain, like
539:
primary motor cortex resulted in significantly greater pain improvement in comparison to the control group (e.g., sham stimulation, stimulation of the DLPFC). However, this effect decreased after treatment ended, but remained significant for three weeks following the extinction of treatment.
501:
Transcutaneous electrical nerve stimulation (TENS) is a self-operated portable device intended to help regulate and control chronic pain via electrical impulses. Limited research has explored the effectiveness of TENS in relation to pain management of multiple sclerosis (MS). MS is a chronic
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and the
American Academy of Pain Medicine. Included in these guidelines is the importance of assessing the patient for the risk of substance abuse, misuse, or addiction. Factors correlated with an elevated risk of opioid misuse include a history of substance use disorder, younger age, major
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Recent research has applied ACT successfully to chronic pain in older adults due to in part of its direction from individual values and being highly customizable to any stage of life. In line with the therapeutic model of ACT, significant increases in process variables, pain acceptance, and
4112:
Pizutti LT, Carissimi A, Valdivia LJ, Ilgenfritz CA, Freitas JJ, Sopezki D, et al. (June 2019). "Evaluation of
Breathworks' Mindfulness for Stress 8-week course: Effects on depressive symptoms, psychiatric symptoms, affects, self-compassion, and mindfulness facets in Brazilian health
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physicians thinking they are not in as much pain as they are reporting. Another occurrence may be physicians simply making the choice not to treat the patient accordingly in spite of the self-reported pain level. Racial disparity is definitely a real issue in the world of pain management.
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medications can provide short, intermediate or long acting analgesia depending upon the specific properties of the medication and whether it is formulated as an extended release drug. Opioid medications may be administered orally, by injection, via nasal mucosa or oral mucosa, rectally,
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Thompson, Trevor; Terhune, Devin B.; Oram, Charlotte; Sharangparni, Joseph; Rouf, Rommana; Solmi, Marco; Veronese, Nicola; Stubbs, Brendon (April 2019). "The effectiveness of hypnosis for pain relief: A systematic review and meta-analysis of 85 controlled experimental trials".
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that may be associated with adult chronic pain. These benefits do not appear to last very long following the therapy. CBT may contribute towards improving the mood of an adult who experiences chronic pain, which could possibility be maintained for longer periods of time.
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drugs are used in chronic pain management and act primarily within the pain pathways of the central nervous system, though peripheral mechanisms have been attributed as well. They are generally used to treat nerve brain that results from injury to the nervous system.
534:
In relation to MS, a study found that after daily tDCS sessions resulted in an individual's subjective report of pain to decrease when compared to a sham condition. In addition, the study found a similar improvement at 1 to 3 days before and after each tDCS session.
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activities such as regular exercise and pacing. Lifestyle changes are also trained to improve sleep patterns and to develop better coping skills for pain and other stressors using various techniques (e.g., relaxation, diaphragmatic breathing, and even biofeedback).
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from the structures implicated as the source of chronic pain. Radiofrequency treatment has been seen to improve pain in patients for facet joint low back pain. However, continuous radiofrequency is more effective in managing pain than pulsed radiofrequency.
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Acupuncture involves the insertion and manipulation of needles into specific points on the body to relieve pain or for therapeutic purposes. An analysis of the 13 highest quality studies of pain treatment with acupuncture, published in
January 2009 in the
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Hypnosis with analgesic (painkiller) has been seen to relieve chronic pain for most people and may be a safe and effective alternative to medications. However, high quality clinical data is needed to generalize to the whole chronic pain population.
2772:"Assessment: efficacy of transcutaneous electric nerve stimulation in the treatment of pain in neurologic disorders (an evidence-based review): report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology"
1569:/paracetamol is not always included in this class of medications. However, acetaminophen may be administered as a single medication or in combination with other analgesics (both NSAIDs and opioids). The alternatively prescribed NSAIDs such as
1902:(CBT) aims to reduce the emotional distress and improve the daily functioning of school-aged children and adolescents with pain by changing the relationship between their thoughts and emotions. In addition this therapy teaches them adaptive
446:. Exercise alone or with other rehabilitation disciplines (such as psychologically based approaches) can have a positive effect on reducing pain. In addition to improving pain, exercise also can improve one's well-being and general health.
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Vanti C, Andreatta S, Borghi S, Guccione AA, Pillastrini P, Bertozzi L (March 2019). "The effectiveness of walking versus exercise on pain and function in chronic low back pain: a systematic review and meta-analysis of randomized trials".
593:. Instead of thermal therapy, where reactant energy is originated through heat, Low Level Light Therapy (LLLT) utilizes photochemical reactions requiring light to function. Photochemical reactions need light in order to function.
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Mayer EK, Ihm JM, Sibell DM, Press JM, Kennedy DJ (August 2013). "ACGME sports, ACGME pain, or non-ACGME sports and spine: which is the ideal fellowship training for PM&R physicians interested in musculoskeletal medicine?".
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and no acupuncture. A systematic review in 2019 reported that acupuncture injection therapy was an effective treatment for patients with nonspecific chronic low back pain, and is widely used in
Southeast Asian countries.
5529:"The effectiveness of generic self-management interventions for patients with chronic musculoskeletal pain on physical function, self-efficacy, pain intensity and physical activity: A systematic review and meta-analysis"
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are also not recommended in new patients except for acute pain where other analgesics are not tolerated or are inappropriate, for pharmacological and misuse-related reasons. In some countries potent synthetics such as
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and postoperatively. The major differences are that it is much more common for the drug to be delivered into the spinal fluid (intrathecal) rather than epidurally, and the pump can be fully implanted under the skin.
5251:
Sandberg, Mårten; Hyldmo, Per
Kristian; Kongstad, Poul; Dahl Friesgaard, Kristian; Raatiniemi, Lasse; Larsen, Robert; Magnusson, Vidar; Rognås, Leif; Kurola, Jouni; Rehn, Marius; Vist, Gunn Elisabeth (November 2020).
4952:"Comparison of analgesic efficacy of acetaminophen monotherapy versus acetaminophen combinations with either pethidine or parecoxib in patients undergoing laparoscopic cholecystectomy: a randomized prospective study"
2381:
Li Y, Yin Y, Jia G, Chen H, Yu L, Wu D (April 2019). "Effects of kinesiotape on pain and disability in individuals with chronic low back pain: a systematic review and meta-analysis of randomized controlled trials".
4292:
Long, Jaqui; Briggs, Michelle; Long, Andrew; Astin, Felicity (October 2016). "Starting where I am: a grounded theory exploration of mindfulness as a facilitator of transition in living with a long-term condition".
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Elmer E.; Atluri, Sairam L.; Bowman, Richard C.; Deer, Timothy R.; Swicegood, John R.; Staats, Peter S.; Smith, Howard S.; Burton, Allen W.; Kloth, David S.; Giordano, James; Manchikanti, Laxmaiah (January 2007).
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Noori-Zadeh A, Bakhtiyari S, Khooz R, Haghani K, Darabi S (February 2019). "Intra-articular ozone therapy efficiently attenuates pain in knee osteoarthritic subjects: A systematic review and meta-analysis".
1597:. There are many NSAIDs such as parecoxib (selective COX-2 inhibitor) with proven effectiveness after different surgical procedures. Wide use of non-opioid analgesics can reduce opioid-induced side-effects.
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transdermally, intravenously, epidurally and intrathecally. In chronic pain conditions that are opioid responsive, a combination of a long-acting (OxyContin, MS Contin, Opana ER, Exalgo and
Methadone) or
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Starrels JL, Becker WC, Alford DP, Kapoor A, Williams AR, Turner BJ (June 2010). "Systematic review: treatment agreements and urine drug testing to reduce opioid misuse in patients with chronic pain".
888:
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Specifically in chronic low back pain, education about the way the brain processes pain in conjunction with routine physiotherapy interventions may provide short term relief of disability and pain.
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could be used on individuals with chronic low back pain to reduce pain. The Center for
Disease Control recommends that physical therapy and exercise can be prescribed as a positive alternative to
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Contreras Lopez WO, Navarro PA, Vargas MD, Alape E, Camacho Lopez PA (February 2019). "Pulsed Radiofrequency Versus Continuous Radiofrequency for Facet Joint Low Back Pain: A Systematic Review".
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general applicability of hypnosis in the treatment of chronic pain, considerably more research will be needed to fully determine the effects of hypnosis for different chronic-pain conditions."
2082:
Zhorov BS, Ananthanarayanan VS (March 2000). "Homology models of mu-opioid receptor with organic and inorganic cations at conserved aspartates in the second and third transmembrane domains".
3113:
Stausholm, Martin Bjørn; Naterstad, Ingvill Fjell; Joensen, Jon; Lopes-Martins, Rodrigo Álvaro Brandão; Sæbø, Humaira; Lund, Hans; Fersum, Kjartan Vibe; Bjordal, Jan Magnus (October 2019).
4183:
Lopes SA, Vannucchi BP, Demarzo M, Cunha ÂG, Nunes MD (February 2019). "Effectiveness of a Mindfulness-Based Intervention in the Management of Musculoskeletal Pain in Nursing Workers".
4049:
Cusens B, Duggan GB, Thorne K, Burch V (2010). "Evaluation of the breathworks mindfulness-based pain management programme: effects on well-being and multiple measures of mindfulness".
2014:
372:
In the nursing profession, one common definition of pain is any problem that is "whatever the experiencing person says it is, existing whenever the experiencing person says it does".
1930:
In recent studies, it has been noted that people who have red-hair through the MC1R receptor gene may react to opioids and perceive pain differently than the rest of the population.
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doctor consultation is appropriate if headaches are severe, persistent, accompanied by fever, vomiting, or speech or balance problems; self-medication should be limited to two weeks
4371:
Brown CA, Jones AK (March 2013). "Psychobiological correlates of improved mental health in patients with musculoskeletal pain after a mindfulness-based pain management program".
3001:"Nonpharmacologic therapies for acute and chronic low back pain: a review of the evidence for an American Pain Society/American College of Physicians clinical practice guideline"
3807:
Accardi MC, Milling LS (August 2009). "The effectiveness of hypnosis for reducing procedure-related pain in children and adolescents: a comprehensive methodological review".
852:(MBPM) is a mindfulness-based intervention (MBI) providing specific applications for people living with chronic pain and illness. Adapting the core concepts and practices of
1321:, known in North America as meperidine, is not recommended for pain management due to its low potency, short duration of action, and toxicity associated with repeated use.
4575:
Aiyer R, Gulati A, Gungor S, Bhatia A, Mehta N (August 2018). "Treatment of Chronic Pain With Various Buprenorphine Formulations: A Systematic Review of Clinical Studies".
1480:
The list below consists of commonly used opioid analgesics which have long-acting formulations. Common brand names for the extended release formulation are in parentheses.
3250:
Rasche D, Ruppolt M, Stippich C, Unterberg A, Tronnier VM (March 2006). "Motor cortex stimulation for long-term relief of chronic neuropathic pain: a 10 year experience".
6292:
Innovation in pain management : the transcript of a witness seminar held by the Wellcome Trust Centre for the History of Medicine at UCL, London, on 12 December 2002
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Innovation in pain management : the transcript of a Witness seminar held by the Wellcome Trust Centre for the History of Medicine at UCL, London, on 12 december 2002
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are commonly used to treat acute or chronic pain symptoms in children and adolescents. However a pediatrician should be consulted before administering any medication.
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Thomas R. Frieden, Harold W. Jaffe, Joanne Cono, et al. CDC Guideline for Prescribing Opioids for Chronic Pain — United States, 2016. MMWR Recomm Rep 2016;65 Pg. 9-10
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Self-management of chronic pain has been described as the individual's ability to manage various aspects of their chronic pain. Self-management can include building
6565:
1938:
Pain management practitioners come from all fields of medicine. In addition to medical practitioners, a pain management team may often benefit from the input of
1654:, "the available evidence from animal and human studies indicates that cannabinoids can have a substantial analgesic effect". In a 2013 review study published in
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therapy are safe interventions that likely reduce pain for patients with chronic low back pain. However, manipulation produces a larger effect than mobilization.
791:(RCTs) evaluated the clinical effectiveness of psychological therapies for the management of adult chronic pain (excluding headaches). There is no evidence that
375:
Pain management includes patient and communication about the pain problem. To define the pain problem, a health care provider will likely ask questions such as:
3115:"Efficacy of low-level laser therapy on pain and disability in knee osteoarthritis: systematic review and meta-analysis of randomised placebo-controlled trials"
205:
provide some pain control in the normal course of their practice, and for the more complex instances of pain, they also call on additional help from a specific
1710:, an alpha-2 receptor agonist, is another drug that has found use as an analgesic adjuvant. In 2021, researchers described a novel type of pain therapy — a
5730:""Brave Men" and "Emotional Women": A Theory-Guided Literature Review on Gender Bias in Health Care and Gendered Norms towards Patients with Chronic Pain"
442:
for decreasing one's pain in multiple injuries, illnesses, or diseases. This can include chronic low back pain, osteoarthritis of the hip and knee, or
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medication is often prescribed along with a shorter-acting medication (oxycodone, morphine or hydromorphone) for breakthrough pain, or exacerbations.
5914:
2534:"A systematic review and meta-analysis of pain neuroscience education for chronic low back pain: Short-and long-term outcomes of pain and disability"
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Subdissociative-dose ketamine (SDK) may be used either alone or as part of a multimodal approach to pain relief for traumatic and nontraumatic pain.
6560:
398:
After asking such questions, the health care provider will have a description of the pain. Pain management will then be used to address that pain.
2903:"Acupuncture treatment for pain: systematic review of randomised clinical trials with acupuncture, placebo acupuncture, and no acupuncture groups"
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3462:"Treatment for chronic pain for adults in the seventh and eighth decades of life: a preliminary study of Acceptance and Commitment Therapy (ACT)"
1769:
5488:"What Works and Does Not Work in a Self-Management Intervention for People With Chronic Pain? Qualitative Systematic Review and Meta-Synthesis"
2862:"A randomized, sham-controlled, proof of principle study of transcranial direct current stimulation for the treatment of pain in fibromyalgia"
2574:
Geneen LJ, Moore RA, Clarke C, Martin D, Colvin LA, Smith BH, et al. (Cochrane Pain, Palliative and Supportive Care Group) (April 2017).
2183:
2009:
each provide certification for a subspecialty in pain management following fellowship training. The fellowship training is recognized by the
1994:
5705:
3525:
Turner JA, Clancy S (April 1988). "Comparison of operant behavioral and cognitive-behavioral group treatment for chronic low back pain".
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Yousefi-Nooraie R, Schonstein E, Heidari K, Rashidian A, Pennick V, Akbari-Kamrani M, et al. (April 2008). Yousefi-Nooraie R (ed.).
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is prescribed for chronic muscular pain in the arms, legs, neck and lower back with an opiate, or sometimes without it or with an NSAID.
505:
496:
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5781:"Racial bias in pain assessment and treatment recommendations, and false beliefs about biological differences between blacks and whites"
7075:
2818:
Zaghi S, Thiele B, Pimentel D, Pimentel T, Fregni F (2011). "Assessment and treatment of pain with non-invasive cortical stimulation".
2006:
1922:(in the case of chronic pain). Many therapists will hold sessions for caregivers to provide them with effective management strategies.
717:
is an implantable medical device that creates electric impulses and applies them near the dorsal surface of the spinal cord provides a
2017:(AOABOS). As the field of pain medicine has grown rapidly, many practitioners have entered the field, some non-ACGME board-certified.
7416:
5946:
Wente SJ (March 2013). "Nonpharmacologic pediatric pain management in emergency departments: a systematic review of the literature".
114:
108:
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Self-Selection all the Way: Improving Patients' Pain Experience and Outcomes on a Pilot Breathworks Mindfulness for Health Programme
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swaddling, rocking, or sucrose via a pacifier. For children and adolescents physical interventions include hot or cold application,
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7015:
705:
used to deliver very small quantities of medications directly to the spinal fluid. This is similar to epidural infusions used in
525:
228:. Relief of pain in general (analgesia) is often an acute affair, whereas managing chronic pain requires additional dimensions.
6299:
6214:
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6176:
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2195:
2163:
2134:
2010:
1963:
1879:
864:', and has been seen as sensitive to concerns about removing mindfulness teaching from its original ethical framework within
7315:
4328:
Doran NJ (June 2014). "Experiencing Wellness Within Illness: Exploring a Mindfulness-Based Approach to Chronic Back Pain".
3659:"Psychological therapies (remotely delivered) for the management of chronic and recurrent pain in children and adolescents"
2002:
1768:"). The Hellenic Society of Algology and the Turkish Algology-Pain Society are the relevant local bodies affiliated to the
427:
5110:
Zogopoulos P, Vasileiou I, Patsouris E, Theocharis SE (February 2013). "The role of endocannabinoids in pain modulation".
1682:
Other drugs which can potentiate conventional analgesics or have analgesic properties in certain circumstances are called
5576:
Eaton, Linda H.; Langford, Dale J.; Meins, Alexa R.; Rue, Tessa; Tauben, David J.; Doorenbos, Ardith Z. (February 2018).
1558:
1190:
883:
857:
2727:
Aboud T, Schuster NM (November 2019). "Pain Management in Multiple Sclerosis: a Review of Available Treatment Options".
729:
Intra-articular ozone therapy has been seen to efficiently alleviate chronic pain in patients with knee osteoarthritis.
7451:
6793:
6318:
2032:
853:
2334:"Effectiveness of spa therapy for patients with chronic low back pain: An updated systematic review and meta-analysis"
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have significant cardiovascular and cerebrovascular risks which have limited their utilization. Common NSAIDs include
6276:
6157:
6147:
5578:"Use of Self-management Interventions for Chronic Pain Management: A Comparison between Rural and Nonrural Residents"
2220:
2057:
1293:
is used across the Americas and Europe for relief of serious chronic pain. Its main slow-release formula is known as
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743:
5396:
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and diseases to support and speed healing. It treats distressing symptoms such as pain and discomfort to reduce any
6555:
6515:
4524:
3295:
1990:
1839:
is present in approximately 15–25% of children and adolescents. It may be caused by an underlying disease, such as
4230:[Mindfulness and Cancer: Application of the MBPM program of Respira Vida Breathworks in cancer patients].
1835:
Acute pain is common in children and adolescents as a result of injury, illness, or necessary medical procedures.
1650:
Evidence of medical marijuana's effect on reducing pain is generally conclusive. Detailed in a 1999 report by the
6676:
1109:
626:
to manage pain or other distress. They are generally viewed as insufficient when used alone, but also as helpful
3501:
1954:, among others. Together the multidisciplinary team can help create a package of care suitable to the patient.
7569:
7441:
6875:
6362:
2648:
1631:
643:
102:
6482:
5202:"Low-dose Ketamine For Acute Pain Control in the Emergency Department: A Systematic Review and Meta-analysis"
2264:
1989:
doctors are also specialists in pain management. The American Society of Interventional Pain Physicians, the
1412:
2289:
Geertzen JH, Van Wilgen CP, Schrier E, Dijkstra PU (March 2006). "Chronic pain in rehabilitation medicine".
30:
This article is about pain management across medicine. For cancer-related pain management specifically, see
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3296:"Interventional techniques: evidence-based practice guidelines in the management of chronic spinal pain"
1702:, are given in conjunction with opioids for neuropathic pain. Orphenadrine and cyclobenzaprine are also
7045:
6745:
5989:
Zagustin TK (August 2013). "The role of cognitive behavioral therapy for chronic pain in adolescents".
2047:
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3711:"Psychological therapies for the management of chronic and recurrent pain in children and adolescents"
1690:, an anticonvulsant, can reduce neuropathic pain itself and can also potentiate opiates. Drugs with
1577:
have limited benefit in chronic pain disorders and with long-term use are associated with significant
1395:
are often used in the management of chronic pain, high doses are associated with an increased risk of
7474:
2624:
902:
17:
6126:
5882:
Weydert JA (2013). "The interdisciplinary management of pediatric pain: Time for more integration".
1866:
Young children can indicate their level of pain by pointing to the appropriate face on a children's
1131:
heartburn lasting more than a week requires medical attention; aspirin and NSAIDs should be avoided
7620:
7610:
7266:
7188:
7183:
7103:
6863:
6714:
6057:
4531:
838:
648:
435:
1272:
and others vary in such ways as duration of action, side effect profile and milligramme potency.
7246:
7220:
1798:
1423:
586:
564:
35:
2483:
Coulter ID, Crawford C, Hurwitz EL, Vernon H, Khorsan R, Suttorp Booth M, Herman PM (May 2018).
689:
may be used to target either the tissue structures and organ/systems responsible for persistent
6838:
6786:
5254:"Ketamine for the treatment of prehospital acute pain: a systematic review of benefit and harm"
3954:"Do mindfulness-based interventions reduce pain intensity? A critical review of the literature"
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668:
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6224:
Daubresse M, Chang HY, Yu Y, Viswanathan S, Shah ND, Stafford RS, et al. (October 2013).
2860:
Fregni F, Gimenes R, Valle AC, Ferreira MJ, Rocha RR, Natalle L, et al. (December 2006).
406:
There are many types of pain management. Each have their own benefits, drawbacks, and limits.
7489:
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6477:
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3000:
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7509:
7469:
7336:
7150:
7145:
7125:
7060:
6912:
6671:
5792:
3610:"Psychological therapies for the management of chronic pain (excluding headache) in adults"
2952:"Acupoint injection for nonspecific chronic low back pain: A protocol of systematic review"
1978:
1848:
1711:
1671:
1670:
is sometimes used as an alternative to opioids for the treatment of acute pain in hospital
1442:
800:
232:
65:
4438:. London: Wellcome Trust Centre for the History of Medicine at University College London.
148:
8:
7615:
7589:
7531:
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4754:
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1907:
1903:
1852:
1619:
1546:
1458:
911:
for managing pain relief with pharmaceutical medicine. It was first described for use in
513:
256:
217:
202:
5796:
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7479:
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7426:
7215:
7168:
7135:
7130:
6880:
6858:
6425:
6355:
6250:
6225:
6103:
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5971:
5815:
5780:
5756:
5729:
5701:
5670:
5661:
Schiller F (1990). "The history of algology, algotherapy, and the role of inhibition".
5602:
5577:
5553:
5528:
5465:
5452:
5423:
5278:
5253:
5233:
5135:
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5040:
4932:
4920:
4822:
4779:
4731:
4706:
4644:
4619:
4600:
4414:
4396:
4353:
4208:
4138:
4019:
3995:"Brief Mindfulness-Based Interventions for Acute and Chronic Pain: A Systematic Review"
3994:
3898:
3832:
3784:
3759:
3735:
3710:
3683:
3658:
3634:
3609:
3585:
3429:
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3197:
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2407:
2358:
2333:
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1683:
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which contain oxycodone are available making it suitable for acute intractable pain or
987:
453:
96:
5363:
5346:
5322:
5305:
5174:
5157:
4950:
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1674:. Ketamine probably reduces pain more than opioids and with less nausea and vomiting.
7575:
7549:
7431:
7401:
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7343:
7326:
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7205:
7195:
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6810:
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6314:
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6272:
6255:
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6191:
6172:
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6132:
6095:
6006:
5963:
5861:
5820:
5761:
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5607:
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5509:
5469:
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5378:
5327:
5283:
5237:
5225:
5179:
5127:
5085:
5075:
5032:
5028:
4973:
4924:
4889:
4814:
4771:
4736:
4649:
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4388:
4345:
4310:
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4130:
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3934:
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3824:
3789:
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3483:
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2191:
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2130:
2099:
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1817:
1802:
1714:
1623:
1472:
Clinical guidelines for prescribing opioids for chronic pain have been issued by the
1430:
1285:
1231:
876:. It has been subject to a range of clinical studies demonstrating its effectiveness.
792:
784:
773:
355:
331:
276:
272:
206:
194:
6107:
6018:
5975:
5422:
Moreno AM, Alemán F, Catroli GF, Hunt M, Hu M, Dailamy A, et al. (March 2021).
5139:
5044:
4826:
4783:
4604:
4400:
4357:
4212:
4142:
3930:
3902:
3836:
3589:
3433:
3389:
3279:
3201:
2702:
2411:
2318:
1213:, may provide greater relief than their separate use. A combination of opioid with
837:
A 2013 meta-analysis of studies that used techniques centered around the concept of
7559:
7251:
7236:
7113:
6988:
6944:
6588:
6438:
6245:
6237:
6087:
5998:
5955:
5891:
5851:
5840:"The assessment and management of acute pain in infants, children, and adolescents"
5810:
5800:
5751:
5741:
5597:
5589:
5548:
5540:
5499:
5447:
5439:
5368:
5358:
5317:
5273:
5265:
5215:
5169:
5119:
5067:
5024:
4963:
4916:
4881:
4806:
4763:
4726:
4718:
4639:
4631:
4584:
4525:"Using Opioids to Treat: Chronic Pain - Comparing Effectiveness, Safety, and Price"
4520:
4380:
4337:
4302:
4274:
4249:
4239:
4192:
4165:
4122:
4058:
4014:
4006:
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3816:
3779:
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3730:
3726:
3722:
3678:
3674:
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3629:
3625:
3621:
3569:
3534:
3473:
3413:
3369:
3334:
3259:
3224:
3181:
3144:
3134:
3126:
3061:
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3053:
3012:
2971:
2963:
2922:
2914:
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2827:
2783:
2736:
2682:
2595:
2591:
2587:
2545:
2504:
2496:
2455:
2445:
2391:
2353:
2345:
2298:
2091:
1142:
opioids may be necessary if other drugs do not control pain and pain is persistent
969:
702:
627:
623:
467:
283:
has healed, and is treated by one practitioner, with drugs such as pain relievers (
190:
4936:
4563:
4087:
2686:
7579:
7524:
7385:
7370:
7353:
7293:
7232:
7210:
6907:
6853:
6833:
6658:
6643:
6241:
5443:
4722:
4702:
4588:
4384:
3709:
Fisher E, Law E, Dudeney J, Palermo TM, Stewart G, Eccleston C (September 2018).
2788:
2771:
2500:
2062:
1986:
1943:
1844:
1786:
Undertreatment of pain is the absence of pain management therapy for a person in
1725:
1703:
1699:
1691:
1626:
and post-stroke pain. These mechanisms vary and in general are more effective in
1582:
1396:
1027:
869:
509:
244:
221:
5269:
5058:
Joy JE, Watson Jr SJ, Benson Jr JA (1999). Watson SJ, Benson JA, Joy JE (eds.).
4278:
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3130:
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7411:
7365:
7178:
7108:
6927:
6735:
6638:
6505:
6091:
6002:
5895:
4885:
3573:
3538:
3417:
3373:
3263:
1966:
1606:
1578:
1462:
1454:
1429:
Most opioid treatment used by patients outside of healthcare settings is oral (
1384:
Drugs of other types can be used to help opioids combat certain types of pain.
1358:
1326:
1269:
1170:
1166:
1147:
964:
are used when the others do not work, or when migraines are frequent or severe
615:
606:
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431:
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7494:
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6983:
6633:
6598:
6550:
6510:
6348:
4341:
3993:
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2395:
2041:
2027:
1737:
1639:
1610:
1566:
1562:
1514:
1490:
1385:
1370:
1314:
1302:
1257:
1249:
1118:
1013:
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777:
619:
610:
590:
582:
335:
268:
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6885:
6870:
6816:
6545:
6530:
6525:
6287:
6259:
6099:
6010:
5967:
5865:
5856:
5839:
5824:
5765:
5746:
5611:
5562:
5513:
5461:
5382:
5347:"Gabapentin as an adjuvant to opioid analgesia for neuropathic cancer pain"
5331:
5287:
5229:
5183:
5131:
5089:
5036:
4977:
4928:
4893:
4818:
4775:
4740:
4676:
4653:
4596:
4392:
4349:
4314:
4204:
4134:
4070:
4028:
3979:
3938:
3894:
3828:
3793:
3744:
3692:
3643:
3581:
3487:
3425:
3381:
3346:
3311:
3271:
3236:
3193:
3158:
3075:
3026:
2985:
2936:
2887:
2839:
2797:
2748:
2694:
2609:
2557:
2518:
2469:
2450:
2403:
2367:
2310:
2103:
2095:
1856:
1836:
1695:
1374:
1339:
1265:
1239:
1161:
1090:
569:
443:
315:
295:
225:
5682:
4010:
3546:
2831:
2258:
2256:
2254:
2252:
1728:
which showed therapeutic potential in three mouse models of chronic pain.
1205:
Paracetamol, an NSAID or paracetamol in a combination product with a weak
1175:
evidence suggests that opioids are not effective in treating fibromyalgia
721:("tingling") sensation that alters the perception of pain by the patient.
7358:
7303:
7200:
7055:
7030:
6848:
6755:
6681:
6666:
6628:
6583:
6540:
6535:
6433:
6407:
6058:"Taking a Subspecialty Exam - American Board of Psychiatry and Neurology"
5504:
5487:
4705:, Yu Y, Viswanathan S, Shah ND, Stafford RS, et al. (October 2013).
4558:
4269:
Agostinis, Alessio; Barrow, Michelle; Taylor, Chad; Gray, Callum (2017).
3039:
2250:
2248:
2246:
2244:
2242:
2240:
2238:
2236:
2234:
2232:
2052:
1939:
1915:
1911:
1895:
1538:
1502:
1438:
1366:
1362:
1335:
1322:
1306:
1281:
1261:
1214:
1186:
1063:
1036:
if inflammation is involved, NSAIDs may work better; short-term use only
912:
907:
873:
718:
690:
672:
548:
339:
314:
identify the cause of pain. Treatment approaches to chronic pain include
170:
31:
5674:
5152:
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2950:
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1085:
this should be short term use; opioids may be necessary for severe pain
364:
7446:
7331:
7298:
7070:
7020:
7005:
7000:
6993:
6978:
6968:
6704:
6618:
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1627:
1615:
1570:
1526:
1343:
1330:
1313:
are used less frequently. Clinical studies have shown that transdermal
796:
706:
694:
568:, was unable to quantify the difference in the effect on pain of real,
288:
236:
5397:"Unique CRISPR gene therapy offers opioid-free chronic pain treatment"
5123:
5109:
4519:
4306:
3970:
3953:
3139:
3112:
2918:
2878:
2861:
2229:
7519:
7261:
7256:
7120:
7098:
6973:
6937:
6740:
6709:
6699:
6593:
6520:
6500:
6492:
6464:
6415:
6402:
5544:
5250:
4968:
4951:
2549:
1974:
1970:
1707:
1590:
1574:
1545:*Methadone and buprenorphine are each used both for the treatment of
1532:
1484:
1318:
1310:
1294:
1290:
1277:
1230:
pain medication is for rapid onset of pain such as from an inflicted
1194:
1105:
1076:
664:
652:
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effects, especially during the commencement or change in dose. When
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6397:
2001:), the American Board of Physical Medicine and Rehabilitation, the
1667:
1594:
1520:
1508:
1496:
1350:
1273:
1253:
1245:
1210:
961:
953:
937:
865:
817:
686:
656:
166:
131:
77:
5071:
4111:
3849:
3657:
Fisher E, Law E, Dudeney J, Eccleston C, Palermo TM (April 2019).
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American Osteopathic Association Bureau of Osteopathic Specialists
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more than two weeks of pain requiring opioid treatment is unusual
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1235:
1218:
1114:
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631:
553:
484:
476:
264:
4991:
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3992:
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5727:
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3915:
3764:
The International Journal of Clinical and Experimental Hypnosis
3171:
1998:
1883:
1753:
1749:
1718:
1622:). These drugs also reduce pain from viruses such as shingles,
1418:
1392:
1298:
1206:
991:
983:
943:
816:
A 2007 review of 13 studies found evidence for the efficacy of
594:
439:
299:
135:
5837:
3249:
977:
some NSAIDs are marketed for cramps, but any NSAID would work
825:
roughly comparable to those of progressive muscle relaxation.
231:
A typical multidisciplinary pain management team may include:
5424:"Long-lasting analgesia via targeted in situ repression of Na
4617:
1761:
1256:
are compared. Semi-synthetic derivatives of morphine such as
1005:
307:
260:
6336:
World Health Organization (WHO) Treatment Guidelines on Pain
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5689:
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Revista de Investigación y Educación en Ciencias de la Salud
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treatment to individuals based on them being male or female
1058:
combinations of opioids may be prescribed if pain is severe
6771:
6371:
6223:
4700:
3608:
Williams AC, Fisher E, Hearn L, Eccleston C (August 2020).
2817:
1787:
1765:
1009:
480:
174:
5643:
5625:
4949:
4796:
4182:
3292:
2900:
2859:
2282:
1600:
1242:
medication is for alleviating long-lasting, ongoing pain.
471:
Aerobic exercise can help when it comes to pain management
5778:
5486:
Devan H, Hale L, Hempel D, Saipe B, Perry MA (May 2018).
4268:
4225:
3656:
1706:, and are useful in painful musculoskeletal conditions.
6566:
congenital insensitivity to pain with partial anhidrosis
5527:
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5345:
Caraceni A, Zecca E, Martini C, De Conno F (June 1999).
6340:
5526:
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3708:
3318:
3286:
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2901:
Madsen MV, Gøtzsche PC, Hróbjartsson A (January 2009).
2573:
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422:
6190:. New York: McGraw-Hill, Medical Publishing Division.
6033:"Study finds link between red hair and pain threshold"
5728:
Samulowitz A, Gremyr I, Eriksson E, Hensing G (2018).
3324:
3165:
2081:
275:. Pain sometimes resolves quickly once the underlying
6171:. Hagerstwon, MD: Lippincott Williams & Wilkins.
5884:
Techniques in Regional Anesthesia and Pain Management
5575:
5200:
Balzer N, McLeod SL, Walsh C, Grewal K (April 2021).
5057:
4851:"Guidelines for prescribing opioids for chronic pain"
3757:
1957:
1541:
bitartrate (Hysingla ER) and bicarbonate (Zohydro ER)
430:
uses a range of physical techniques such as heat and
5485:
2649:"Chronic Pain: Symptoms, Diagnosis, & Treatment"
1906:
strategies. Integrated interventions in CBT include
844:
737:
224:
of anyone experiencing pain, whether acute pain or
220:
approach for easing the suffering and improving the
6076:
5244:
4291:
4088:"What is Mindfulness based Pain Management (MBPM)?"
2431:
1156:medical attention is recommended if pain persists.
5700:
5062:Marijuana and Medicine: Assessing the Science Base
5059:
4865:
4515:
4513:
4511:
4509:
4507:
4505:
4503:
4501:
4499:
4497:
4495:
4493:
4491:
4489:
4487:
4485:
4483:
4481:
4479:
4477:
4475:
3850:American Psychological Association (2 July 2004).
2151:
2118:
1071:if inflammation involved, NSAIDs may work better.
5838:American Academy of Pediatrics (September 2001).
4473:
4471:
4469:
4467:
4465:
4463:
4461:
4459:
4457:
4455:
3999:Journal of Alternative and Complementary Medicine
3951:
3760:"Hypnotherapy for the management of chronic pain"
2532:Wood, Lianne; Hendrick, Paul A. (February 2019).
2188:Pain management: A practical guide for clinicians
1445:is rarely needed for patients with chronic pain.
921:Common types of pain and typical drug management
7602:
6561:congenital insensitivity to pain with anhidrosis
5146:
2949:
2769:
2262:
1561:(NSAID). They work by inhibiting the release of
1346:is a newer agent introduced in the last decade.
724:
651:procedures for pain control, typically used for
6166:
5785:Proceedings of the National Academy of Sciences
5008:
4871:
3872:
3758:Elkins G, Jensen MP, Patterson DR (July 2007).
2331:
2210:
2170:Pain management: an interdisciplinary approach.
1770:International Association for the Study of Pain
1638:, and an example of an antidepressant would be
1618:can be due to chronic high blood sugar levels (
756:
330:; interventional procedures, physical therapy,
6285:
5920:. American Medical Association. Archived from
4900:
4452:
4431:
3952:Reiner K, Tibi L, Lipsitz JD (February 2013).
3806:
3459:
2154:Pain management: an interdisciplinary approach
1748:The medical treatment of pain as practiced in
1441:and skin patches can be prescribed. An opioid
685:, direct introduction of medication and nerve
557:Acupuncture can sometimes help to relieve pain
6787:
6356:
6185:
6145:
6070:
3852:"Hypnosis for the relief and control of pain"
3527:Journal of Consulting and Clinical Psychology
2726:
2432:Dowell D, Haegerich TM, Chou R (March 2016).
2181:
2149:
1962:Pain physicians are often fellowship-trained
1933:
1297:. Short-acting tablets, capsules, syrups and
6149:Pain Medicine and Management: Just the Facts
5193:
3524:
2763:
2531:
2380:
1995:American Osteopathic Board of Anesthesiology
1581:. The use of selective NSAIDs designated as
637:
6124:
5663:History and Philosophy of the Life Sciences
4415:"WHO - WHO's cancer pain ladder for adults"
4155:
3715:The Cochrane Database of Systematic Reviews
3663:The Cochrane Database of Systematic Reviews
3614:The Cochrane Database of Systematic Reviews
3046:The Cochrane Database of Systematic Reviews
2998:
2580:The Cochrane Database of Systematic Reviews
2075:
506:Transcutaneous electrical nerve stimulation
497:Transcutaneous electrical nerve stimulation
391:What, if anything, makes the pain increase?
7076:Reproductive endocrinology and infertility
6794:
6780:
6363:
6349:
5877:
5875:
5338:
4906:
4753:
4370:
3751:
3553:
2007:American Board of Psychiatry and Neurology
1224:
1099:opioids usually needed if pain is severe.
27:Interdisciplinary approach for easing pain
7417:Bachelor of Medicine, Bachelor of Surgery
6249:
5855:
5814:
5804:
5755:
5745:
5601:
5552:
5503:
5451:
5372:
5362:
5321:
5306:"Current pharmacotherapy of chronic pain"
5277:
5219:
5173:
4967:
4730:
4643:
4253:
4243:
4018:
3969:
3783:
3734:
3682:
3633:
3559:
3477:
3208:
3148:
3138:
3065:
3016:
2975:
2926:
2877:
2787:
2599:
2508:
2459:
2449:
2357:
2125:. U.K.: Greenwich Medical Media. p.
1217:can be frequently used such as Percocet,
872:and is delivered through the programs of
832:
732:
475:Physical activity interventions, such as
462:
388:What, if anything, makes the pain lessen?
368:Commonly used scale to depict pain levels
115:Bachelor of Medicine, Bachelor of Surgery
109:Bachelor of Medicine, Bachelor of Surgery
6188:Principles and practice of pain medicine
5988:
5982:
5660:
5303:
5154:American College of Emergency Physicians
4811:10.7326/0003-4819-152-11-201006010-00004
4158:British Journal of Healthcare Management
3919:Neuroscience & Biobehavioral Reviews
3506:American Psychological Association (APA)
2770:Dubinsky RM, Miyasaki J (January 2010).
1861:
1557:The other major group of analgesics are
1200:
552:
466:
363:
153:
142:
6204:
5881:
5872:
5112:Fundamental & Clinical Pharmacology
5014:
4636:10.7326/0003-4819-152-2-201001190-00006
4051:Clinical Psychology & Psychotherapy
3800:
3502:"What Is Cognitive Behavioral Therapy?"
3018:10.7326/0003-4819-147-7-200710020-00007
2121:Chronic pain management: the essentials
2084:Archives of Biochemistry and Biophysics
1656:Fundamental & Clinical Pharmacology
1601:Antidepressants and antiepileptic drugs
1317:is effective at reducing chronic pain.
589:is an effective therapy for relieving
526:Transcranial direct-current stimulation
14:
7603:
6308:
6266:
5939:
5909:
5907:
5905:
5351:Journal of Pain and Symptom Management
5310:Journal of Pain and Symptom Management
4521:Consumer Reports Health Best Buy Drugs
4425:
4082:
4080:
3866:
3455:
3453:
3451:
3449:
3447:
3445:
3443:
3214:
2855:
2853:
2851:
2849:
2820:Restorative Neurology and Neuroscience
2813:
2811:
2809:
2807:
2729:Current Treatment Options in Neurology
2722:
2720:
2718:
2716:
2714:
2712:
2622:
1743:
34:. For the album by Bubba Sparxxx, see
6775:
6344:
5945:
5481:
5479:
5299:
5297:
4432:Reynolds LA, Tansey EM, eds. (2004).
4327:
4044:
4042:
4040:
4038:
3704:
3702:
3603:
3601:
3599:
3327:Neurosurgery Clinics of North America
3217:Neurosurgery Clinics of North America
2569:
2567:
2427:
2425:
2423:
2421:
2116:
2011:American Board of Medical Specialties
1880:nonsteroidal anti-inflammatory agents
508:has been found to be ineffective for
7555:
7316:Physical medicine and rehabilitation
5831:
4874:The Medical Clinics of North America
4848:
3854:. American Psychological Association
2992:
2265:"Pain Relief: What You Need to Know"
2003:American Board of Emergency Medicine
1559:nonsteroidal anti-inflammatory drugs
1553:Nonsteroidal anti-inflammatory drugs
1457:will occur. Other risks can include
428:Physical medicine and rehabilitation
423:Physical medicine and rehabilitation
417:
7565:
6037:National Institutes of Health (NIH)
5902:
4364:
4321:
4285:
4262:
4219:
4176:
4077:
3843:
3460:McCracken LM, Jones R (July 2012).
3440:
3406:Complementary Therapies in Medicine
2999:Chou R, Huffman LH (October 2007).
2846:
2804:
2709:
2263:Consumer Reports (April 28, 2016).
1677:
1284:. It can also be administered via
1191:nonsteroidal anti-inflammatory drug
858:mindfulness-based cognitive therapy
24:
7452:Medical Scientist Training Program
6313:. Johns Hopkins University Press.
6146:Staats P, Wallace M (March 2015).
6125:Diwan S, Staats P (January 2015).
6117:
5476:
5294:
4921:10.1097/01.smj.0000223946.19256.17
4149:
4105:
4035:
3699:
3596:
2564:
2418:
2033:List of investigational analgesics
1958:Pain medicine in the United States
1731:
1634:. A common anti-epileptic drug is
854:mindfulness-based stress reduction
401:
334:, application of ice or heat; and
267:. The team may also include other
25:
7632:
6329:
6128:Atlas of Pain Medicine Procedures
5175:10.1016/j.annemergmed.2017.06.043
4756:Current Pain and Headache Reports
4273:. British Pain Society ASM 2017.
2438:MMWR. Recommendations and Reports
2058:Pain management during childbirth
1775:
1565:, which cause inflammatory pain.
850:Mindfulness-based pain management
845:Mindfulness-based pain management
780:within the field very difficult.
744:Acceptance and commitment therapy
738:Acceptance and commitment therapy
581:Research has found evidence that
209:devoted to pain, which is called
7584:
7574:
7564:
7554:
7545:
7544:
6556:Congenital insensitivity to pain
6516:Paroxysmal extreme pain disorder
6167:Fausett HJ, Warfield CA (2002).
6050:
5029:10.1111/j.1533-2500.2006.00055.x
3479:10.1111/j.1526-4637.2012.01407.x
3186:10.1111/j.1533-2500.2006.00056.x
1991:American Board of Anesthesiology
600:
576:
349:
7585:
6086:(8): 718–23, discussion 723–5.
6025:
5772:
5721:
5654:
5636:
5618:
5569:
5520:
5415:
5389:
5103:
5051:
4984:
4943:
4842:
4833:
4790:
4747:
4694:
4669:
4660:
4611:
4568:
4564:Over-the-counter pain relievers
4551:
4407:
3986:
3945:
3931:10.1016/j.neubiorev.2019.02.013
3909:
3650:
3518:
3494:
3396:
3353:
3243:
3106:
3082:
3033:
2943:
2894:
2665:
2641:
2616:
2525:
2476:
1645:
1453:are used for prolonged periods
1110:gastroesophageal reflux disease
1079:or pain from dental procedures
929:typical initial drug treatment
675:drug delivery system implants.
306:during treatment, healing, and
7442:Doctor of Osteopathic Medicine
6876:Oral and maxillofacial surgery
6271:. Chicago Scholarship Online.
6186:Bajwa ZH, Warfield CA (2004).
5734:Pain Research & Management
5432:Science Translational Medicine
4115:Journal of Clinical Psychology
3875:Journal of Behavioral Medicine
3809:Journal of Behavioral Medicine
3727:10.1002/14651858.CD003968.pub5
3675:10.1002/14651858.cd011118.pub3
3626:10.1002/14651858.CD007407.pub4
3058:10.1002/14651858.CD005107.pub4
2592:10.1002/14651858.CD011279.pub3
2374:
2325:
2211:Pasero C, McCaffery M (1999).
2204:
2175:
2150:Main CJ, Spanswick CC (2000).
2143:
2110:
1824:
1632:complex regional pain syndrome
896:
644:Interventional pain management
542:
512:. However, it might help with
189:) in various dimensions, from
103:Doctor of Osteopathic medicine
13:
1:
5364:10.1016/S0885-3924(99)00033-0
5323:10.1016/s0885-3924(99)00124-4
2687:10.1080/09638288.2017.1410730
2675:Disability and Rehabilitation
2291:Disability and Rehabilitation
2182:Thienhaus O, Cole BE (2002).
2069:
1413:National Institutes of Health
1096:paracetamol, NSAIDs, opioids
725:Intra-articular ozone therapy
216:Pain management often uses a
7422:Bachelor of Medical Sciences
7189:Neurosurgical anesthesiology
6801:
6242:10.1097/MLR.0b013e3182a95d86
5948:Journal of Emergency Nursing
5444:10.1126/scitranslmed.aay9056
5304:Portenoy RK (January 2000).
5162:Annals of Emergency Medicine
4723:10.1097/MLR.0b013e3182a95d86
4681:Food and Drug Administration
4589:10.1213/ANE.0000000000002718
4385:10.1097/AJP.0b013e31824c5d9f
4373:The Clinical Journal of Pain
2789:10.1212/WNL.0b013e3181c918fc
2653:NIH MedlinePlus the Magazine
2501:10.1016/j.spinee.2018.01.013
2184:"The classification of pain"
1900:Cognitive behavioral therapy
1409:Food and Drug Administration
1181:
789:randomized controlled trials
763:Cognitive behavioral therapy
757:Cognitive behavioral therapy
516:as well as other illnesses.
344:cognitive behavioral therapy
7:
5915:"Pediatric Pain Management"
5270:10.1136/bmjopen-2020-038134
5207:Academic Emergency Medicine
5168:(3). Elsevier BV: 446–448.
4799:Annals of Internal Medicine
4624:Annals of Internal Medicine
4330:Qualitative Health Research
4295:Journal of Advanced Nursing
4279:10.13140/RG.2.2.14157.23526
4245:10.37536/RIECS.2018.3.2.101
4170:10.12968/bjhc.2018.24.5.235
3131:10.1136/bmjopen-2019-031142
3005:Annals of Internal Medicine
2968:10.1097/MD.0000000000016478
2625:"Exercise and Chronic Pain"
2350:10.1097/MD.0000000000017092
2020:
1831:Pain management in children
1801:and the recommendations of
1661:
1493:(Exalgo, Hydromorph Contin)
942:paracetamol/acetaminophen,
811:
657:epidural steroid injections
622:are both examples of using
10:
7637:
6209:. Philadelphia: Saunders.
6092:10.1016/j.pmrj.2013.07.004
6003:10.1016/j.pmrj.2013.05.009
5896:10.1053/j.trap.2014.07.006
4886:10.1016/j.mcna.2006.10.011
3574:10.1016/j.pain.2011.05.004
3539:10.1037/0022-006x.56.2.261
3418:10.1016/j.ctim.2018.11.023
3374:10.1016/j.wneu.2018.10.191
3264:10.1016/j.pain.2005.12.006
2048:Pain Catastrophizing Scale
1934:Professional certification
1828:
1779:
1630:pain disorders as well as
1583:selective COX-2 inhibitors
1411:stated: "According to the
1402:
1342:are used for severe pain.
1052:severe pain after surgery
884:Excessive citations inline
760:
741:
641:
604:
546:
523:
494:
353:
29:
7540:
7462:
7400:
7161:
7089:
7044:
6953:
6824:
6809:
6723:
6690:
6657:
6611:
6576:
6491:
6447:
6424:
6385:
6378:
6311:Pain: A Political History
6169:Manual of pain management
5960:10.1016/j.jen.2012.09.011
5594:10.1016/j.pmn.2017.09.004
5066:. Institute of Medicine.
4768:10.1007/s11916-009-0086-x
4197:10.1016/j.pmn.2018.02.065
3887:10.1007/s10865-005-9031-6
3821:10.1007/s10865-009-9207-6
3776:10.1080/00207140701338621
3339:10.1016/j.nec.2004.02.009
3229:10.1016/j.nec.2004.02.012
2741:10.1007/s11940-019-0601-2
2303:10.1080/09638280500287437
2190:. CRC Press. p. 29.
2158:. Churchill Livingstone.
1926:In red-haired individuals
1511:, transdermal (Duragesic)
1041:minor pain after surgery
1033:NSAIDs, muscle relaxants
1004:severe trauma, such as a
920:
903:World Health Organization
638:Interventional procedures
123:
88:
83:
71:
59:
51:
46:
7376:Transplantation medicine
7267:Clinical neurophysiology
7184:Obstetric anesthesiology
7104:Interventional radiology
6864:Digestive system surgery
6370:
5533:European Journal of Pain
4909:Southern Medical Journal
4577:Anesthesia and Analgesia
4559:MedlinePlus Encyclopedia
4342:10.1177/1049732314529662
2866:Arthritis and Rheumatism
2623:University, Utah State.
2538:European Journal of Pain
2396:10.1177/0269215518817804
1517:*, transdermal (Butrans)
1276:has the benefit of less
1197:will relieve mild pain.
999:opioids not recommended
982:minor trauma, such as a
649:Interventional radiology
394:When did the pain start?
379:How intense is the pain?
296:chronic (long-term) pain
294:Effective management of
287:) and occasionally also
7247:Intensive care medicine
7221:Mass gathering medicine
7066:Maternal–fetal medicine
6677:Posteromarginal nucleus
6612:Measurement and testing
5806:10.1073/pnas.1516047113
5648:Algoloji - Ağrı Derneği
5582:Pain Management Nursing
4185:Pain Management Nursing
2384:Clinical Rehabilitation
1952:occupational therapists
1799:evidence-based medicine
1760:(from the Greek άλγος,
1280:release and thus fewer
1225:Moderate to severe pain
889:considered for deletion
669:spinal cord stimulators
587:low level laser therapy
565:British Medical Journal
519:
490:
382:How does the pain feel?
253:recreational therapists
249:occupational therapists
42:Pain Medicine Physician
36:Pain Management (album)
6839:Cardiothoracic surgery
5857:10.1542/peds.108.3.793
2451:10.15585/mmwr.rr6501e1
2186:. In Weiner RS (ed.).
2096:10.1006/abbi.1999.1529
1948:clinical psychologists
1871:
1782:Undertreatment of pain
1717:method for repressing
1535:* (Metadol, Methadose)
1189:(acetaminophen), or a
1047:opioids rarely needed
868:. It was developed by
833:Mindfulness meditation
733:Psychological approach
715:spinal cord stimulator
661:facet joint injections
558:
472:
463:Exercise interventions
369:
241:clinical psychologists
197:and challenging. Most
159:
151:
7490:Personalized medicine
7349:Reproductive medicine
7274:Occupational medicine
7228:Evolutionary medicine
6761:Drug-seeking behavior
6649:Visual analogue scale
4011:10.1089/acm.2018.0351
2832:10.3233/RNN-2011-0615
2213:Pain: clinical manual
1865:
1672:emergency departments
1652:Institute of Medicine
1474:American Pain Society
1201:Mild to moderate pain
1127:proton-pump inhibitor
679:Pulsed radiofrequency
556:
470:
367:
322:(pain killer drugs),
233:medical practitioners
157:
146:
7510:Traditional medicine
7470:Alternative medicine
7337:Addiction psychiatry
7151:Transfusion medicine
7146:Medical microbiology
7061:Gynecologic oncology
6913:Reproductive surgery
6672:Anterolateral system
5747:10.1155/2018/6358624
5710:, Human Rights Watch
5316:(1 Suppl): S16–S20.
2215:. St. Louis: Mosby.
1979:emergency physicians
1908:relaxation technique
1853:functional disorders
1849:rheumatoid arthritis
1499:(M-Eslon, MS Contin)
1264:(Numorphan, Opana),
1153:paracetamol, NSAIDs
1139:paracetamol, NSAIDs
1082:paracetamol, NSAIDs
1068:paracetamol, NSAIDs
1044:paracetamol, NSAIDs
996:paracetamol, NSAIDs
958:paracetamol, NSAIDs
257:physician assistants
203:health professionals
173:involving relief of
158:Image of visual pain
147:Active and inactive
7532:History of medicine
7515:Veterinary medicine
7322:Preventive medicine
7174:Adolescent medicine
7016:Infectious diseases
6205:Waldman SD (2006).
5797:2016PNAS..113.4296H
2040:, an example of an
1997:(recognized by the
1855:such as migraines,
1744:Society and culture
1620:diabetic neuropathy
1459:chemical dependency
1349:For moderate pain,
1236:post-operative pain
1016:, or severe sprain
905:(WHO) recommends a
514:diabetic neuropathy
43:
7480:Molecular oncology
7437:Doctor of Medicine
7427:Master of Medicine
7344:Radiation oncology
7216:Emergency medicine
7169:Addiction medicine
7136:Clinical chemistry
7131:Clinical pathology
6923:Transplant surgery
6881:Orthopedic surgery
6859:Colorectal surgery
6751:Philosophy of pain
6426:Respiratory system
6267:Graham SS (2015).
5702:Human Rights Watch
5505:10.1093/ptj/pzy029
5221:10.1111/acem.14159
4996:www.brainfacts.org
4956:Medicinski Glasnik
4540:: Consumer Reports
4127:10.1002/jclp.22749
3362:World Neurosurgery
1872:
1841:sickle cell anemia
1790:when treatment is
1694:activity, such as
1684:analgesic adjuvant
1549:and as analgesics
1379:dextropropoxyphene
1136:chronic back pain
630:to other forms of
559:
473:
385:Where is the pain?
370:
338:measures, such as
318:measures, such as
273:massage therapists
160:
152:
149:μ-opioid receptors
97:Doctor of Medicine
90:Education required
41:
7598:
7597:
7432:Master of Surgery
7396:
7395:
7381:Tropical medicine
7327:Prison healthcare
7242:Hospital medicine
7206:Disaster medicine
7196:Aviation medicine
7011:Hospital medicine
6918:Surgical oncology
6903:Pediatric surgery
6897:
6844:Endocrine surgery
6769:
6768:
6624:Cold pressor test
6607:
6606:
6309:Wailoo K (2014).
6301:978-0-85484-097-7
6216:978-0-7216-0334-6
6197:978-0-07-144349-4
6178:978-0-7817-2313-8
6138:978-0-07-173876-7
5791:(16): 4296–4301.
5438:(584): eaay9056.
5124:10.1111/fcp.12008
5081:978-0-309-07155-0
4915:(11): 1245–1255.
4538:Yonkers, New York
4445:978-0-85484-097-7
4307:10.1111/jan.12998
4301:(10): 2445–2456.
4094:. 22 January 2019
3971:10.1111/pme.12006
2919:10.1136/bmj.a3115
2879:10.1002/art.22195
2872:(12): 3988–3998.
2629:extension.usu.edu
2489:The Spine Journal
2197:978-0-8493-0926-7
2165:978-0-443-05683-3
2136:978-1-900151-85-6
2117:Hardy PA (1997).
2038:Opioid comparison
1967:anesthesiologists
1884:opioid analgesics
1803:medical specialty
1715:epigenome editing
1624:phantom limb pain
1381:(less commonly).
1303:breakthrough pain
1286:transdermal patch
1179:
1178:
1030:or pulled muscle
793:behaviour therapy
785:systematic review
774:systematic review
665:neurolytic blocks
653:chronic back pain
418:Physical approach
356:Threshold of pain
332:physical exercise
218:multidisciplinary
207:medical specialty
141:
140:
16:(Redirected from
7628:
7588:
7587:
7578:
7568:
7567:
7558:
7557:
7548:
7547:
7252:Medical genetics
7237:General practice
7114:Nuclear medicine
6989:Gastroenterology
6945:Vascular surgery
6895:
6822:
6821:
6796:
6789:
6782:
6773:
6772:
6724:Related concepts
6715:Pain eradication
6473:
6460:
6411:
6383:
6382:
6379:By region/system
6365:
6358:
6351:
6342:
6341:
6324:
6305:
6282:
6263:
6253:
6220:
6201:
6182:
6163:
6142:
6112:
6111:
6074:
6068:
6067:
6065:
6064:
6054:
6048:
6047:
6045:
6044:
6029:
6023:
6022:
5986:
5980:
5979:
5943:
5937:
5936:
5934:
5932:
5927:on June 11, 2014
5926:
5919:
5911:
5900:
5899:
5890:(2013): 188–94.
5879:
5870:
5869:
5859:
5835:
5829:
5828:
5818:
5808:
5776:
5770:
5769:
5759:
5749:
5725:
5719:
5718:
5717:
5715:
5698:
5687:
5686:
5658:
5652:
5651:
5640:
5634:
5633:
5622:
5616:
5615:
5605:
5573:
5567:
5566:
5556:
5545:10.1002/ejp.1253
5539:(9): 1577–1596.
5524:
5518:
5517:
5507:
5492:Physical Therapy
5483:
5474:
5473:
5455:
5419:
5413:
5412:
5410:
5408:
5393:
5387:
5386:
5376:
5366:
5342:
5336:
5335:
5325:
5301:
5292:
5291:
5281:
5248:
5242:
5241:
5223:
5197:
5191:
5190:
5177:
5150:
5144:
5143:
5107:
5101:
5100:
5098:
5096:
5065:
5055:
5049:
5048:
5012:
5006:
5005:
5003:
5002:
4988:
4982:
4981:
4971:
4969:10.17392/1245-21
4947:
4941:
4940:
4904:
4898:
4897:
4869:
4863:
4862:
4849:King SA (2010).
4846:
4840:
4837:
4831:
4830:
4794:
4788:
4787:
4751:
4745:
4744:
4734:
4698:
4692:
4691:
4689:
4687:
4673:
4667:
4664:
4658:
4657:
4647:
4615:
4609:
4608:
4572:
4566:
4555:
4549:
4548:
4547:
4545:
4529:
4517:
4450:
4449:
4429:
4423:
4422:
4411:
4405:
4404:
4368:
4362:
4361:
4325:
4319:
4318:
4289:
4283:
4282:
4266:
4260:
4259:
4257:
4247:
4223:
4217:
4216:
4180:
4174:
4173:
4153:
4147:
4146:
4113:professionals".
4109:
4103:
4102:
4100:
4099:
4084:
4075:
4074:
4046:
4033:
4032:
4022:
3990:
3984:
3983:
3973:
3949:
3943:
3942:
3913:
3907:
3906:
3870:
3864:
3863:
3861:
3859:
3847:
3841:
3840:
3804:
3798:
3797:
3787:
3755:
3749:
3748:
3738:
3721:(10): CD003968.
3706:
3697:
3696:
3686:
3654:
3648:
3647:
3637:
3605:
3594:
3593:
3568:(8): 1701–1702.
3557:
3551:
3550:
3522:
3516:
3515:
3513:
3512:
3498:
3492:
3491:
3481:
3457:
3438:
3437:
3400:
3394:
3393:
3357:
3351:
3350:
3322:
3316:
3315:
3290:
3284:
3283:
3247:
3241:
3240:
3212:
3206:
3205:
3169:
3163:
3162:
3152:
3142:
3110:
3104:
3103:
3101:
3100:
3086:
3080:
3079:
3069:
3037:
3031:
3030:
3020:
2996:
2990:
2989:
2979:
2947:
2941:
2940:
2930:
2898:
2892:
2891:
2881:
2857:
2844:
2843:
2815:
2802:
2801:
2791:
2767:
2761:
2760:
2724:
2707:
2706:
2669:
2663:
2662:
2660:
2659:
2645:
2639:
2638:
2636:
2635:
2620:
2614:
2613:
2603:
2571:
2562:
2561:
2550:10.1002/ejp.1314
2529:
2523:
2522:
2512:
2480:
2474:
2473:
2463:
2453:
2429:
2416:
2415:
2378:
2372:
2371:
2361:
2329:
2323:
2322:
2286:
2280:
2279:
2277:
2275:
2269:Consumer Reports
2260:
2227:
2226:
2208:
2202:
2201:
2179:
2173:
2172:
2157:
2147:
2141:
2140:
2124:
2114:
2108:
2107:
2079:
1944:physiotherapists
1818:African-American
1704:muscle relaxants
1678:Other analgesics
1547:opioid addiction
1437:or liquid), but
1424:extended release
1193:(NSAID) such as
970:menstrual cramps
918:
917:
892:
703:intrathecal pump
624:auditory stimuli
414:deeper problem.
271:specialists and
245:physiotherapists
165:is an aspect of
73:Activity sectors
44:
40:
21:
7636:
7635:
7631:
7630:
7629:
7627:
7626:
7625:
7621:Palliative care
7611:Pain management
7601:
7600:
7599:
7594:
7536:
7525:Chief physician
7458:
7403:
7392:
7386:Travel medicine
7371:Sports medicine
7354:Sexual medicine
7294:Palliative care
7289:Pain management
7233:Family medicine
7211:Diving medicine
7157:
7085:
7047:
7040:
6956:
6949:
6908:Plastic surgery
6854:General surgery
6834:Cardiac surgery
6815:
6813:
6805:
6800:
6770:
6765:
6719:
6686:
6659:Pathophysiology
6653:
6644:Tail flick test
6603:
6572:
6487:
6471:
6458:
6449:Musculoskeletal
6443:
6420:
6409:
6374:
6369:
6332:
6327:
6321:
6302:
6279:
6236:(10): 870–878.
6217:
6207:Pain Management
6198:
6179:
6160:
6152:. McGraw Hill.
6139:
6131:. McGraw Hill.
6120:
6118:Further reading
6115:
6075:
6071:
6062:
6060:
6056:
6055:
6051:
6042:
6040:
6031:
6030:
6026:
5987:
5983:
5944:
5940:
5930:
5928:
5924:
5917:
5913:
5912:
5903:
5880:
5873:
5836:
5832:
5777:
5773:
5726:
5722:
5713:
5711:
5704:(2 June 2011),
5699:
5690:
5659:
5655:
5642:
5641:
5637:
5626:"Αρχική Σελίδα"
5624:
5623:
5619:
5574:
5570:
5525:
5521:
5484:
5477:
5427:
5420:
5416:
5406:
5404:
5403:. 11 March 2021
5395:
5394:
5390:
5343:
5339:
5302:
5295:
5264:(11): e038134.
5249:
5245:
5198:
5194:
5151:
5147:
5108:
5104:
5094:
5092:
5082:
5056:
5052:
5013:
5009:
5000:
4998:
4990:
4989:
4985:
4948:
4944:
4905:
4901:
4870:
4866:
4855:Psychiatr Times
4847:
4843:
4838:
4834:
4805:(11): 712–720.
4795:
4791:
4752:
4748:
4717:(10): 870–878.
4699:
4695:
4685:
4683:
4675:
4674:
4670:
4665:
4661:
4616:
4612:
4573:
4569:
4556:
4552:
4543:
4541:
4527:
4518:
4453:
4446:
4430:
4426:
4413:
4412:
4408:
4369:
4365:
4326:
4322:
4290:
4286:
4267:
4263:
4224:
4220:
4181:
4177:
4154:
4150:
4110:
4106:
4097:
4095:
4092:Breathworks CIC
4086:
4085:
4078:
4063:10.1002/cpp.653
4047:
4036:
3991:
3987:
3950:
3946:
3914:
3910:
3871:
3867:
3857:
3855:
3848:
3844:
3805:
3801:
3756:
3752:
3707:
3700:
3669:(4): CD011118.
3655:
3651:
3620:(5): CD007407.
3606:
3597:
3558:
3554:
3523:
3519:
3510:
3508:
3500:
3499:
3495:
3458:
3441:
3401:
3397:
3358:
3354:
3323:
3319:
3291:
3287:
3248:
3244:
3213:
3209:
3170:
3166:
3125:(10): e031142.
3111:
3107:
3098:
3096:
3088:
3087:
3083:
3052:(2): CD005107.
3038:
3034:
2997:
2993:
2948:
2944:
2899:
2895:
2858:
2847:
2816:
2805:
2768:
2764:
2725:
2710:
2670:
2666:
2657:
2655:
2647:
2646:
2642:
2633:
2631:
2621:
2617:
2586:(2): CD011279.
2572:
2565:
2530:
2526:
2481:
2477:
2430:
2419:
2379:
2375:
2330:
2326:
2287:
2283:
2273:
2271:
2261:
2230:
2223:
2209:
2205:
2198:
2180:
2176:
2166:
2148:
2144:
2137:
2115:
2111:
2080:
2076:
2072:
2067:
2063:Pain psychology
2023:
1987:Palliative care
1964:board-certified
1960:
1936:
1878:Acetaminophen,
1845:cystic fibrosis
1833:
1827:
1784:
1778:
1746:
1734:
1732:Self-management
1726:gene expression
1722:
1700:cyclobenzaprine
1692:anticholinergic
1680:
1664:
1648:
1603:
1579:adverse effects
1555:
1405:
1397:opioid overdose
1365:are used, with
1227:
1203:
1184:
1122:
899:
877:
870:Vidyamala Burch
862:loving-kindness
847:
835:
814:
801:catastrophizing
765:
759:
746:
740:
735:
727:
683:neuromodulation
646:
640:
613:
605:Main articles:
603:
579:
551:
545:
528:
522:
510:lower back pain
499:
493:
465:
425:
420:
404:
402:Adverse effects
362:
352:
328:anticonvulsants
324:antidepressants
316:pharmacological
222:quality of life
163:Pain management
128:
126:
91:
74:
62:
61:Occupation type
39:
28:
23:
22:
15:
12:
11:
5:
7634:
7624:
7623:
7618:
7613:
7596:
7595:
7593:
7592:
7582:
7572:
7562:
7552:
7541:
7538:
7537:
7535:
7534:
7529:
7528:
7527:
7517:
7512:
7507:
7502:
7497:
7492:
7487:
7482:
7477:
7472:
7466:
7464:
7463:Related topics
7460:
7459:
7457:
7456:
7455:
7454:
7444:
7439:
7434:
7429:
7424:
7419:
7414:
7412:Medical school
7408:
7406:
7398:
7397:
7394:
7393:
7391:
7390:
7389:
7388:
7378:
7373:
7368:
7366:Sleep medicine
7363:
7362:
7361:
7351:
7346:
7341:
7340:
7339:
7329:
7324:
7319:
7313:
7308:
7307:
7306:
7296:
7291:
7286:
7281:
7276:
7271:
7270:
7269:
7259:
7254:
7249:
7244:
7239:
7230:
7225:
7224:
7223:
7213:
7208:
7203:
7198:
7193:
7192:
7191:
7186:
7179:Anesthesiology
7176:
7171:
7165:
7163:
7159:
7158:
7156:
7155:
7154:
7153:
7148:
7143:
7138:
7133:
7128:
7118:
7117:
7116:
7111:
7109:Neuroradiology
7106:
7095:
7093:
7087:
7086:
7084:
7083:
7078:
7073:
7068:
7063:
7058:
7052:
7050:
7046:Obstetrics and
7042:
7041:
7039:
7038:
7033:
7028:
7023:
7018:
7013:
7008:
7003:
6998:
6997:
6996:
6986:
6981:
6976:
6971:
6961:
6959:
6951:
6950:
6948:
6947:
6942:
6941:
6940:
6930:
6928:Trauma surgery
6925:
6920:
6915:
6910:
6905:
6900:
6899:
6898:
6891:Otolaryngology
6888:
6883:
6878:
6873:
6868:
6867:
6866:
6861:
6851:
6846:
6841:
6836:
6830:
6828:
6819:
6817:subspecialties
6807:
6806:
6799:
6798:
6791:
6784:
6776:
6767:
6766:
6764:
6763:
6758:
6753:
6748:
6743:
6738:
6736:Pain tolerance
6733:
6731:Pain threshold
6727:
6725:
6721:
6720:
6718:
6717:
6712:
6707:
6702:
6696:
6694:
6688:
6687:
6685:
6684:
6679:
6674:
6669:
6663:
6661:
6655:
6654:
6652:
6651:
6646:
6641:
6639:Hot plate test
6636:
6631:
6626:
6621:
6615:
6613:
6609:
6608:
6605:
6604:
6602:
6601:
6596:
6591:
6586:
6580:
6578:
6574:
6573:
6571:
6570:
6569:
6568:
6563:
6553:
6548:
6543:
6538:
6533:
6528:
6523:
6518:
6513:
6508:
6506:Pain asymbolia
6503:
6497:
6495:
6489:
6488:
6486:
6485:
6480:
6475:
6467:
6462:
6453:
6451:
6445:
6444:
6442:
6441:
6436:
6430:
6428:
6422:
6421:
6419:
6418:
6413:
6405:
6400:
6395:
6389:
6387:
6380:
6376:
6375:
6368:
6367:
6360:
6353:
6345:
6339:
6338:
6331:
6330:External links
6328:
6326:
6325:
6320:978-1421413655
6319:
6306:
6300:
6283:
6277:
6264:
6221:
6215:
6202:
6196:
6183:
6177:
6164:
6158:
6143:
6137:
6121:
6119:
6116:
6114:
6113:
6069:
6049:
6024:
5997:(8): 697–704.
5981:
5954:(2): 140–150.
5938:
5901:
5871:
5850:(3): 793–797.
5830:
5771:
5720:
5688:
5653:
5635:
5617:
5568:
5519:
5498:(5): 381–397.
5475:
5425:
5414:
5388:
5357:(6): 441–445.
5337:
5293:
5243:
5214:(4): 444–454.
5192:
5145:
5102:
5080:
5050:
5007:
4983:
4942:
4899:
4864:
4841:
4832:
4789:
4746:
4693:
4668:
4659:
4610:
4583:(2): 529–538.
4567:
4550:
4451:
4444:
4424:
4406:
4379:(3): 233–244.
4363:
4336:(6): 749–760.
4320:
4284:
4261:
4234:(in Spanish).
4218:
4175:
4164:(5): 235–241.
4148:
4121:(6): 970–984.
4104:
4076:
4034:
4005:(3): 265–278.
3985:
3964:(2): 230–242.
3944:
3908:
3865:
3842:
3815:(4): 328–339.
3799:
3770:(3): 275–287.
3750:
3698:
3649:
3595:
3552:
3533:(2): 261–266.
3517:
3493:
3472:(7): 860–867.
3439:
3395:
3352:
3333:(3): 335–342.
3317:
3300:Pain Physician
3285:
3258:(1–2): 43–52.
3242:
3223:(3): 297–306.
3207:
3164:
3105:
3081:
3032:
3011:(7): 492–504.
2991:
2962:(29): e16478.
2942:
2893:
2845:
2826:(6): 439–451.
2803:
2782:(2): 173–176.
2762:
2708:
2681:(6): 622–632.
2664:
2640:
2615:
2563:
2544:(2): 234–249.
2524:
2495:(5): 866–879.
2475:
2417:
2390:(4): 596–606.
2373:
2344:(37): e17092.
2324:
2297:(6): 363–367.
2281:
2228:
2221:
2203:
2196:
2174:
2164:
2142:
2135:
2109:
2073:
2071:
2068:
2066:
2065:
2060:
2055:
2050:
2045:
2035:
2030:
2024:
2022:
2019:
2013:(ABMS) or the
1959:
1956:
1935:
1932:
1829:Main article:
1826:
1823:
1780:Main article:
1777:
1776:Undertreatment
1774:
1745:
1742:
1733:
1730:
1720:
1679:
1676:
1663:
1660:
1647:
1644:
1607:antidepressant
1602:
1599:
1563:prostaglandins
1554:
1551:
1543:
1542:
1536:
1530:
1524:
1518:
1512:
1506:
1500:
1494:
1488:
1455:drug tolerance
1404:
1401:
1359:dihydrocodeine
1327:dextromoramide
1270:hydromorphinol
1226:
1223:
1202:
1199:
1183:
1180:
1177:
1176:
1173:
1171:anticonvulsant
1167:antidepressant
1164:
1158:
1157:
1154:
1151:
1148:osteoarthritis
1144:
1143:
1140:
1137:
1133:
1132:
1129:
1120:
1112:
1101:
1100:
1097:
1094:
1087:
1086:
1083:
1080:
1073:
1072:
1069:
1066:
1060:
1059:
1056:
1053:
1049:
1048:
1045:
1042:
1038:
1037:
1034:
1031:
1024:
1023:
1020:
1017:
1001:
1000:
997:
994:
979:
978:
975:
972:
966:
965:
959:
956:
950:
949:
946:
940:
934:
933:
930:
927:
923:
922:
898:
895:
846:
843:
834:
831:
813:
810:
799:and potential
761:Main article:
758:
755:
742:Main article:
739:
736:
734:
731:
726:
723:
642:Main article:
639:
636:
616:Audioanalgesia
607:Audioanalgesia
602:
599:
578:
575:
547:Main article:
544:
541:
524:Main article:
521:
518:
495:Main article:
492:
489:
464:
461:
432:electrotherapy
424:
421:
419:
416:
403:
400:
396:
395:
392:
389:
386:
383:
380:
360:Pain tolerance
351:
348:
193:and simple to
139:
138:
129:
124:
121:
120:
119:
118:
112:
106:
100:
92:
89:
86:
85:
81:
80:
75:
72:
69:
68:
63:
60:
57:
56:
53:
49:
48:
26:
9:
6:
4:
3:
2:
7633:
7622:
7619:
7617:
7614:
7612:
7609:
7608:
7606:
7591:
7583:
7581:
7577:
7573:
7571:
7563:
7561:
7553:
7551:
7543:
7542:
7539:
7533:
7530:
7526:
7523:
7522:
7521:
7518:
7516:
7513:
7511:
7508:
7506:
7503:
7501:
7498:
7496:
7495:Public health
7493:
7491:
7488:
7486:
7483:
7481:
7478:
7476:
7475:Allied health
7473:
7471:
7468:
7467:
7465:
7461:
7453:
7450:
7449:
7448:
7445:
7443:
7440:
7438:
7435:
7433:
7430:
7428:
7425:
7423:
7420:
7418:
7415:
7413:
7410:
7409:
7407:
7405:
7399:
7387:
7384:
7383:
7382:
7379:
7377:
7374:
7372:
7369:
7367:
7364:
7360:
7357:
7356:
7355:
7352:
7350:
7347:
7345:
7342:
7338:
7335:
7334:
7333:
7330:
7328:
7325:
7323:
7320:
7317:
7314:
7312:
7309:
7305:
7302:
7301:
7300:
7297:
7295:
7292:
7290:
7287:
7285:
7284:Oral medicine
7282:
7280:
7279:Ophthalmology
7277:
7275:
7272:
7268:
7265:
7264:
7263:
7260:
7258:
7255:
7253:
7250:
7248:
7245:
7243:
7240:
7238:
7234:
7231:
7229:
7226:
7222:
7219:
7218:
7217:
7214:
7212:
7209:
7207:
7204:
7202:
7199:
7197:
7194:
7190:
7187:
7185:
7182:
7181:
7180:
7177:
7175:
7172:
7170:
7167:
7166:
7164:
7160:
7152:
7149:
7147:
7144:
7142:
7141:Cytopathology
7139:
7137:
7134:
7132:
7129:
7127:
7124:
7123:
7122:
7119:
7115:
7112:
7110:
7107:
7105:
7102:
7101:
7100:
7097:
7096:
7094:
7092:
7088:
7082:
7081:Urogynecology
7079:
7077:
7074:
7072:
7069:
7067:
7064:
7062:
7059:
7057:
7054:
7053:
7051:
7049:
7043:
7037:
7034:
7032:
7029:
7027:
7024:
7022:
7019:
7017:
7014:
7012:
7009:
7007:
7004:
7002:
6999:
6995:
6992:
6991:
6990:
6987:
6985:
6984:Endocrinology
6982:
6980:
6977:
6975:
6972:
6970:
6966:
6963:
6962:
6960:
6958:
6952:
6946:
6943:
6939:
6936:
6935:
6934:
6931:
6929:
6926:
6924:
6921:
6919:
6916:
6914:
6911:
6909:
6906:
6904:
6901:
6894:
6893:
6892:
6889:
6887:
6884:
6882:
6879:
6877:
6874:
6872:
6869:
6865:
6862:
6860:
6857:
6856:
6855:
6852:
6850:
6847:
6845:
6842:
6840:
6837:
6835:
6832:
6831:
6829:
6827:
6823:
6820:
6818:
6812:
6808:
6804:
6797:
6792:
6790:
6785:
6783:
6778:
6777:
6774:
6762:
6759:
6757:
6754:
6752:
6749:
6747:
6744:
6742:
6739:
6737:
6734:
6732:
6729:
6728:
6726:
6722:
6716:
6713:
6711:
6708:
6706:
6703:
6701:
6698:
6697:
6695:
6693:
6689:
6683:
6680:
6678:
6675:
6673:
6670:
6668:
6665:
6664:
6662:
6660:
6656:
6650:
6647:
6645:
6642:
6640:
6637:
6635:
6634:Grimace scale
6632:
6630:
6627:
6625:
6622:
6620:
6617:
6616:
6614:
6610:
6600:
6599:Low back pain
6597:
6595:
6592:
6590:
6587:
6585:
6582:
6581:
6579:
6575:
6567:
6564:
6562:
6559:
6558:
6557:
6554:
6552:
6551:Referred pain
6549:
6547:
6544:
6542:
6539:
6537:
6534:
6532:
6529:
6527:
6524:
6522:
6519:
6517:
6514:
6512:
6511:Pain disorder
6509:
6507:
6504:
6502:
6499:
6498:
6496:
6494:
6490:
6484:
6483:Delayed-onset
6481:
6479:
6476:
6474:
6468:
6466:
6463:
6461:
6455:
6454:
6452:
6450:
6446:
6440:
6437:
6435:
6432:
6431:
6429:
6427:
6423:
6417:
6414:
6412:
6406:
6404:
6401:
6399:
6396:
6394:
6391:
6390:
6388:
6386:Head and neck
6384:
6381:
6377:
6373:
6366:
6361:
6359:
6354:
6352:
6347:
6346:
6343:
6337:
6334:
6333:
6322:
6316:
6312:
6307:
6303:
6297:
6293:
6289:
6286:Reynolds LA,
6284:
6280:
6278:9780226264059
6274:
6270:
6265:
6261:
6257:
6252:
6247:
6243:
6239:
6235:
6231:
6227:
6222:
6218:
6212:
6208:
6203:
6199:
6193:
6189:
6184:
6180:
6174:
6170:
6165:
6161:
6159:9780071817455
6155:
6151:
6150:
6144:
6140:
6134:
6130:
6129:
6123:
6122:
6109:
6105:
6101:
6097:
6093:
6089:
6085:
6081:
6073:
6059:
6053:
6038:
6034:
6028:
6020:
6016:
6012:
6008:
6004:
6000:
5996:
5992:
5985:
5977:
5973:
5969:
5965:
5961:
5957:
5953:
5949:
5942:
5923:
5916:
5910:
5908:
5906:
5897:
5893:
5889:
5885:
5878:
5876:
5867:
5863:
5858:
5853:
5849:
5845:
5841:
5834:
5826:
5822:
5817:
5812:
5807:
5802:
5798:
5794:
5790:
5786:
5782:
5775:
5767:
5763:
5758:
5753:
5748:
5743:
5739:
5735:
5731:
5724:
5709:
5708:
5703:
5697:
5695:
5693:
5684:
5680:
5676:
5672:
5668:
5664:
5657:
5649:
5645:
5639:
5631:
5627:
5621:
5613:
5609:
5604:
5599:
5595:
5591:
5587:
5583:
5579:
5572:
5564:
5560:
5555:
5550:
5546:
5542:
5538:
5534:
5530:
5523:
5515:
5511:
5506:
5501:
5497:
5493:
5489:
5482:
5480:
5471:
5467:
5463:
5459:
5454:
5449:
5445:
5441:
5437:
5433:
5429:
5418:
5402:
5398:
5392:
5384:
5380:
5375:
5370:
5365:
5360:
5356:
5352:
5348:
5341:
5333:
5329:
5324:
5319:
5315:
5311:
5307:
5300:
5298:
5289:
5285:
5280:
5275:
5271:
5267:
5263:
5259:
5255:
5247:
5239:
5235:
5231:
5227:
5222:
5217:
5213:
5209:
5208:
5203:
5196:
5189:
5185:
5181:
5176:
5171:
5167:
5163:
5159:
5155:
5149:
5141:
5137:
5133:
5129:
5125:
5121:
5117:
5113:
5106:
5091:
5087:
5083:
5077:
5073:
5072:10.17226/6376
5069:
5064:
5063:
5054:
5046:
5042:
5038:
5034:
5030:
5026:
5022:
5018:
5017:Pain Practice
5011:
4997:
4993:
4987:
4979:
4975:
4970:
4965:
4961:
4957:
4953:
4946:
4938:
4934:
4930:
4926:
4922:
4918:
4914:
4910:
4903:
4895:
4891:
4887:
4883:
4880:(1): 97–111.
4879:
4875:
4868:
4860:
4856:
4852:
4845:
4836:
4828:
4824:
4820:
4816:
4812:
4808:
4804:
4800:
4793:
4785:
4781:
4777:
4773:
4769:
4765:
4761:
4757:
4750:
4742:
4738:
4733:
4728:
4724:
4720:
4716:
4712:
4708:
4704:
4701:Daubresse M,
4697:
4682:
4678:
4672:
4663:
4655:
4651:
4646:
4641:
4637:
4633:
4629:
4625:
4621:
4614:
4606:
4602:
4598:
4594:
4590:
4586:
4582:
4578:
4571:
4565:
4561:
4560:
4554:
4539:
4535:
4534:
4526:
4523:(July 2012),
4522:
4516:
4514:
4512:
4510:
4508:
4506:
4504:
4502:
4500:
4498:
4496:
4494:
4492:
4490:
4488:
4486:
4484:
4482:
4480:
4478:
4476:
4474:
4472:
4470:
4468:
4466:
4464:
4462:
4460:
4458:
4456:
4447:
4441:
4437:
4436:
4428:
4420:
4416:
4410:
4402:
4398:
4394:
4390:
4386:
4382:
4378:
4374:
4367:
4359:
4355:
4351:
4347:
4343:
4339:
4335:
4331:
4324:
4316:
4312:
4308:
4304:
4300:
4296:
4288:
4280:
4276:
4272:
4265:
4256:
4251:
4246:
4241:
4237:
4233:
4229:
4222:
4214:
4210:
4206:
4202:
4198:
4194:
4190:
4186:
4179:
4171:
4167:
4163:
4159:
4152:
4144:
4140:
4136:
4132:
4128:
4124:
4120:
4116:
4108:
4093:
4089:
4083:
4081:
4072:
4068:
4064:
4060:
4056:
4052:
4045:
4043:
4041:
4039:
4030:
4026:
4021:
4016:
4012:
4008:
4004:
4000:
3996:
3989:
3981:
3977:
3972:
3967:
3963:
3959:
3958:Pain Medicine
3955:
3948:
3940:
3936:
3932:
3928:
3924:
3920:
3912:
3904:
3900:
3896:
3892:
3888:
3884:
3881:(1): 95–124.
3880:
3876:
3869:
3853:
3846:
3838:
3834:
3830:
3826:
3822:
3818:
3814:
3810:
3803:
3795:
3791:
3786:
3781:
3777:
3773:
3769:
3765:
3761:
3754:
3746:
3742:
3737:
3732:
3728:
3724:
3720:
3716:
3712:
3705:
3703:
3694:
3690:
3685:
3680:
3676:
3672:
3668:
3664:
3660:
3653:
3645:
3641:
3636:
3631:
3627:
3623:
3619:
3615:
3611:
3604:
3602:
3600:
3591:
3587:
3583:
3579:
3575:
3571:
3567:
3563:
3556:
3548:
3544:
3540:
3536:
3532:
3528:
3521:
3507:
3503:
3497:
3489:
3485:
3480:
3475:
3471:
3467:
3466:Pain Medicine
3463:
3456:
3454:
3452:
3450:
3448:
3446:
3444:
3435:
3431:
3427:
3423:
3419:
3415:
3411:
3407:
3399:
3391:
3387:
3383:
3379:
3375:
3371:
3367:
3363:
3356:
3348:
3344:
3340:
3336:
3332:
3328:
3321:
3313:
3309:
3305:
3301:
3297:
3289:
3281:
3277:
3273:
3269:
3265:
3261:
3257:
3253:
3246:
3238:
3234:
3230:
3226:
3222:
3218:
3211:
3203:
3199:
3195:
3191:
3187:
3183:
3179:
3175:
3174:Pain Practice
3168:
3160:
3156:
3151:
3146:
3141:
3136:
3132:
3128:
3124:
3120:
3116:
3109:
3095:
3091:
3085:
3077:
3073:
3068:
3063:
3059:
3055:
3051:
3047:
3043:
3036:
3028:
3024:
3019:
3014:
3010:
3006:
3002:
2995:
2987:
2983:
2978:
2973:
2969:
2965:
2961:
2957:
2953:
2946:
2938:
2934:
2929:
2924:
2920:
2916:
2912:
2908:
2904:
2897:
2889:
2885:
2880:
2875:
2871:
2867:
2863:
2856:
2854:
2852:
2850:
2841:
2837:
2833:
2829:
2825:
2821:
2814:
2812:
2810:
2808:
2799:
2795:
2790:
2785:
2781:
2777:
2773:
2766:
2758:
2754:
2750:
2746:
2742:
2738:
2734:
2730:
2723:
2721:
2719:
2717:
2715:
2713:
2704:
2700:
2696:
2692:
2688:
2684:
2680:
2676:
2668:
2654:
2650:
2644:
2630:
2626:
2619:
2611:
2607:
2602:
2597:
2593:
2589:
2585:
2581:
2577:
2570:
2568:
2559:
2555:
2551:
2547:
2543:
2539:
2535:
2528:
2520:
2516:
2511:
2506:
2502:
2498:
2494:
2490:
2486:
2479:
2471:
2467:
2462:
2457:
2452:
2447:
2443:
2439:
2435:
2428:
2426:
2424:
2422:
2413:
2409:
2405:
2401:
2397:
2393:
2389:
2385:
2377:
2369:
2365:
2360:
2355:
2351:
2347:
2343:
2339:
2335:
2328:
2320:
2316:
2312:
2308:
2304:
2300:
2296:
2292:
2285:
2270:
2266:
2259:
2257:
2255:
2253:
2251:
2249:
2247:
2245:
2243:
2241:
2239:
2237:
2235:
2233:
2224:
2222:0-8151-5609-X
2218:
2214:
2207:
2199:
2193:
2189:
2185:
2178:
2171:
2167:
2161:
2156:
2155:
2146:
2138:
2132:
2128:
2123:
2122:
2113:
2105:
2101:
2097:
2093:
2089:
2085:
2078:
2074:
2064:
2061:
2059:
2056:
2054:
2051:
2049:
2046:
2043:
2042:equianalgesic
2039:
2036:
2034:
2031:
2029:
2028:Equianalgesic
2026:
2025:
2018:
2016:
2012:
2008:
2004:
2000:
1996:
1992:
1988:
1984:
1983:psychiatrists
1980:
1976:
1972:
1968:
1965:
1955:
1953:
1949:
1945:
1941:
1931:
1928:
1927:
1923:
1921:
1917:
1913:
1909:
1905:
1901:
1897:
1893:
1887:
1885:
1881:
1876:
1869:
1864:
1860:
1858:
1854:
1850:
1846:
1842:
1838:
1832:
1822:
1819:
1814:
1809:
1804:
1800:
1797:Consensus in
1795:
1793:
1789:
1783:
1773:
1771:
1767:
1763:
1759:
1755:
1751:
1741:
1739:
1738:self-efficacy
1729:
1727:
1724:
1716:
1713:
1709:
1705:
1701:
1697:
1693:
1689:
1686:medications.
1685:
1675:
1673:
1669:
1659:
1657:
1653:
1643:
1641:
1640:amitriptyline
1637:
1633:
1629:
1625:
1621:
1617:
1612:
1611:antiepileptic
1608:
1598:
1596:
1592:
1588:
1584:
1580:
1576:
1572:
1568:
1567:Acetaminophen
1564:
1560:
1550:
1548:
1540:
1537:
1534:
1531:
1528:
1525:
1522:
1519:
1516:
1515:Buprenorphine
1513:
1510:
1507:
1504:
1501:
1498:
1495:
1492:
1491:Hydromorphone
1489:
1486:
1483:
1482:
1481:
1478:
1475:
1470:
1468:
1464:
1460:
1456:
1452:
1446:
1444:
1440:
1439:suppositories
1436:
1432:
1427:
1425:
1420:
1416:
1414:
1410:
1407:In 2009, the
1400:
1398:
1394:
1389:
1387:
1386:Amitriptyline
1382:
1380:
1376:
1372:
1371:ethylmorphine
1368:
1364:
1360:
1356:
1352:
1347:
1345:
1341:
1337:
1332:
1328:
1324:
1320:
1316:
1315:buprenorphine
1312:
1308:
1304:
1300:
1296:
1292:
1287:
1283:
1279:
1275:
1271:
1267:
1263:
1259:
1258:hydromorphone
1255:
1252:to which all
1251:
1250:gold standard
1247:
1243:
1241:
1237:
1233:
1222:
1221:, or Norco.
1220:
1216:
1215:acetaminophen
1212:
1208:
1198:
1196:
1192:
1188:
1174:
1172:
1168:
1165:
1163:
1160:
1159:
1155:
1152:
1149:
1146:
1145:
1141:
1138:
1135:
1134:
1130:
1128:
1124:
1116:
1113:
1111:
1107:
1103:
1102:
1098:
1095:
1092:
1089:
1088:
1084:
1081:
1078:
1075:
1074:
1070:
1067:
1065:
1062:
1061:
1057:
1054:
1051:
1050:
1046:
1043:
1040:
1039:
1035:
1032:
1029:
1026:
1025:
1021:
1018:
1015:
1014:bone fracture
1011:
1007:
1003:
1002:
998:
995:
993:
989:
985:
981:
980:
976:
973:
971:
968:
967:
963:
960:
957:
955:
952:
951:
947:
945:
941:
939:
936:
935:
931:
928:
925:
924:
919:
916:
914:
910:
909:
904:
894:
890:
886:
885:
881:
875:
871:
867:
863:
859:
855:
851:
842:
840:
830:
826:
822:
819:
809:
805:
802:
798:
794:
790:
786:
781:
779:
778:meta-analysis
775:
769:
764:
754:
750:
745:
730:
722:
720:
716:
711:
708:
704:
699:
696:
692:
688:
684:
680:
676:
674:
670:
666:
662:
658:
654:
650:
645:
635:
633:
629:
625:
621:
620:music therapy
617:
612:
611:Music therapy
608:
601:Sound therapy
598:
596:
592:
591:low back pain
588:
584:
583:light therapy
577:Light therapy
574:
571:
567:
566:
555:
550:
540:
536:
532:
527:
517:
515:
511:
507:
503:
498:
488:
486:
482:
478:
469:
460:
457:
455:
451:
447:
445:
441:
437:
433:
429:
415:
411:
407:
399:
393:
390:
387:
384:
381:
378:
377:
376:
373:
366:
361:
357:
350:Defining pain
347:
345:
341:
337:
336:psychological
333:
329:
325:
321:
317:
311:
309:
305:
301:
297:
292:
290:
286:
282:
278:
274:
270:
269:mental health
266:
262:
258:
254:
250:
246:
242:
238:
234:
229:
227:
223:
219:
214:
212:
211:pain medicine
208:
204:
200:
196:
192:
188:
184:
180:
176:
172:
168:
164:
156:
150:
145:
137:
133:
130:
122:
116:
113:
110:
107:
104:
101:
98:
95:
94:
93:
87:
82:
79:
76:
70:
67:
64:
58:
54:
50:
45:
37:
33:
19:
7500:Rural health
7485:Nanomedicine
7288:
7036:Rheumatology
6967: /
6886:Hand surgery
6871:Neurosurgery
6691:
6546:Phantom pain
6531:Hyperalgesia
6526:Chronic pain
6410:(swallowing)
6408:Odynophagia
6310:
6291:
6268:
6233:
6230:Medical Care
6229:
6206:
6187:
6168:
6148:
6127:
6083:
6079:
6072:
6061:. Retrieved
6052:
6041:. Retrieved
6039:. 2021-04-19
6036:
6027:
5994:
5990:
5984:
5951:
5947:
5941:
5929:. Retrieved
5922:the original
5887:
5883:
5847:
5843:
5833:
5788:
5784:
5774:
5737:
5733:
5723:
5712:, retrieved
5706:
5669:(1): 27–49.
5666:
5662:
5656:
5647:
5638:
5629:
5620:
5585:
5581:
5571:
5536:
5532:
5522:
5495:
5491:
5435:
5431:
5428:1.7 in mice"
5417:
5405:. Retrieved
5400:
5391:
5354:
5350:
5340:
5313:
5309:
5261:
5257:
5246:
5211:
5205:
5195:
5187:
5165:
5161:
5148:
5118:(1): 64–80.
5115:
5111:
5105:
5093:. Retrieved
5061:
5053:
5023:(1): 27–33.
5020:
5016:
5010:
4999:. Retrieved
4995:
4992:"BrainFacts"
4986:
4962:(1): 27–32.
4959:
4955:
4945:
4912:
4908:
4902:
4877:
4873:
4867:
4858:
4854:
4844:
4835:
4802:
4798:
4792:
4762:(1): 17–21.
4759:
4755:
4749:
4714:
4711:Medical Care
4710:
4696:
4684:. Retrieved
4680:
4671:
4662:
4630:(2): 85–92.
4627:
4623:
4613:
4580:
4576:
4570:
4557:
4553:
4542:, retrieved
4532:
4434:
4427:
4418:
4409:
4376:
4372:
4366:
4333:
4329:
4323:
4298:
4294:
4287:
4270:
4264:
4238:(2): 33–45.
4235:
4231:
4221:
4191:(1): 32–38.
4188:
4184:
4178:
4161:
4157:
4151:
4118:
4114:
4107:
4096:. Retrieved
4091:
4057:(1): 63–78.
4054:
4050:
4002:
3998:
3988:
3961:
3957:
3947:
3922:
3918:
3911:
3878:
3874:
3868:
3856:. Retrieved
3845:
3812:
3808:
3802:
3767:
3763:
3753:
3718:
3714:
3666:
3662:
3652:
3617:
3613:
3565:
3561:
3555:
3530:
3526:
3520:
3509:. Retrieved
3505:
3496:
3469:
3465:
3409:
3405:
3398:
3365:
3361:
3355:
3330:
3326:
3320:
3306:(1): 7–111.
3303:
3299:
3288:
3255:
3251:
3245:
3220:
3216:
3210:
3180:(1): 34–38.
3177:
3173:
3167:
3122:
3118:
3108:
3097:. Retrieved
3093:
3084:
3049:
3045:
3035:
3008:
3004:
2994:
2959:
2955:
2945:
2910:
2906:
2896:
2869:
2865:
2823:
2819:
2779:
2775:
2765:
2732:
2728:
2678:
2674:
2667:
2656:. Retrieved
2652:
2643:
2632:. Retrieved
2628:
2618:
2583:
2579:
2541:
2537:
2527:
2492:
2488:
2478:
2441:
2437:
2387:
2383:
2376:
2341:
2337:
2327:
2294:
2290:
2284:
2272:. Retrieved
2268:
2212:
2206:
2187:
2177:
2169:
2153:
2145:
2120:
2112:
2090:(1): 31–49.
2087:
2083:
2077:
1975:physiatrists
1971:neurologists
1961:
1937:
1929:
1925:
1924:
1888:
1877:
1873:
1857:fibromyalgia
1851:. Cancer or
1837:Chronic pain
1834:
1812:
1807:
1796:
1785:
1757:
1747:
1735:
1712:CRISPR-dCas9
1696:orphenadrine
1681:
1665:
1655:
1649:
1646:Cannabinoids
1604:
1556:
1544:
1529:(Nucynta ER)
1479:
1471:
1447:
1428:
1417:
1406:
1390:
1383:
1375:propoxyphene
1348:
1340:ketobemidone
1282:side effects
1266:nicomorphine
1260:(Dilaudid),
1244:
1240:Chronic pain
1234:or to treat
1228:
1204:
1185:
1162:fibromyalgia
1104:pain due to
1091:kidney stone
906:
900:
882:
848:
836:
827:
823:
815:
806:
782:
770:
766:
751:
747:
728:
712:
700:
677:
647:
614:
580:
563:
560:
537:
533:
529:
504:
500:
474:
458:
454:mobilization
450:Manipulative
448:
444:fibromyalgia
426:
412:
408:
405:
397:
374:
371:
312:
293:
230:
226:chronic pain
215:
210:
187:pain control
186:
182:
178:
162:
161:
7570:Wikiproject
7359:Venereology
7304:Neonatology
7201:Dermatology
7056:Gynaecology
7048:gynaecology
7031:Pulmonology
6849:Eye surgery
6811:Specialties
6756:Cancer pain
6682:Substance P
6667:Nociception
6629:Dolorimeter
6584:Pelvic pain
6541:Hyperpathia
6536:Hypoalgesia
6457:Arthralgia
6439:Pleurodynia
6434:Sore throat
5740:: 6358624.
5644:"Ana Sayfa"
5630:HPS-Pain.gr
5588:(1): 8–13.
5374:2434/913025
4255:10017/35501
3925:: 298–310.
3412:: 240–247.
3368:: 390–396.
2444:(1): 1–49.
2053:Pain ladder
1940:pharmacists
1916:biofeedback
1912:mindfulness
1896:acupuncture
1825:In children
1628:neuropathic
1539:Hydrocodone
1523:(Ultram ER)
1503:Oxymorphone
1487:(OxyContin)
1367:nicocodeine
1363:hydrocodone
1336:piritramide
1323:Pentazocine
1307:Diamorphine
1262:oxymorphone
1187:Paracetamol
1064:muscle ache
913:cancer pain
908:pain ladder
897:Medications
874:Breathworks
856:(MBSR) and
839:mindfulness
783:In 2020, a
719:paresthesia
695:nociceptors
691:nociception
673:intrathecal
549:Acupuncture
543:Acupuncture
436:kinesiotape
340:biofeedback
289:anxiolytics
237:pharmacists
179:pain relief
171:health care
84:Description
32:Cancer pain
7616:Acute pain
7605:Categories
7332:Psychiatry
7318:(PM&R)
7311:Phlebology
7299:Pediatrics
7126:Anatomical
7091:Diagnostic
7071:Obstetrics
7021:Nephrology
7006:Hematology
7001:Geriatrics
6994:Hepatology
6979:Cardiology
6969:Immunology
6705:Anesthesia
6692:Management
6619:Pain scale
6589:Proctalgia
6493:Neurologic
6393:Eye strain
6080:PM & R
6063:2015-09-19
6043:2024-09-21
5991:PM & R
5844:Pediatrics
5001:2019-04-03
4544:28 October
4098:2020-05-22
3511:2020-07-14
3140:1956/23441
3099:2024-02-02
2735:(12): 62.
2658:2019-03-12
2634:2024-03-02
2070:References
1920:acceptance
1868:pain scale
1756:is called
1688:Gabapentin
1636:gabapentin
1616:Neuropathy
1571:ketoprofen
1527:Tapentadol
1505:(Opana ER)
1344:Tapentadol
1331:dipipanone
1123:antagonist
926:Pain type
797:disability
655:, include
354:See also:
320:analgesics
285:analgesics
201:and other
199:physicians
127:employment
111:(M.B.B.S.)
47:Occupation
7520:Physician
7404:education
7262:Neurology
7257:Narcology
7121:Pathology
7099:Radiology
6974:Angiology
6938:Andrology
6741:Suffering
6710:Cordotomy
6700:Analgesia
6521:Allodynia
6501:Neuralgia
6465:Bone pain
6416:Toothache
6288:Tansey EM
5931:March 27,
5470:232170826
5401:New Atlas
5238:225063965
2913:: a3115.
2776:Neurology
2757:208302550
1808:perceived
1792:indicated
1708:Clonidine
1666:Low-dose
1591:ibuprofen
1575:piroxicam
1533:Methadone
1485:Oxycodone
1467:addiction
1463:diversion
1443:injection
1319:Pethidine
1311:methadone
1295:OxyContin
1291:Oxycodone
1278:histamine
1268:(Vilan),
1254:narcotics
1195:ibuprofen
1182:Mild pain
1106:heartburn
1077:toothache
988:abrasions
932:comments
887:is being
304:suffering
281:pathology
183:analgesia
132:Hospitals
125:Fields of
66:Specialty
55:Physician
18:Analgesia
7550:Category
7026:Oncology
6957:medicine
6955:Internal
6803:Medicine
6746:SOCRATES
6472:(muscle)
6470:Myalgia
6398:Headache
6290:(2004).
6260:24025657
6108:39220409
6100:23953018
6019:20013375
6011:23953015
5976:10884181
5968:23199786
5866:11533354
5825:27044069
5766:29682130
5675:23330469
5612:29153296
5563:29845678
5514:29669089
5462:33692134
5407:18 April
5383:10388250
5332:10687334
5288:33234621
5258:BMJ Open
5230:33098707
5184:28844277
5156:(2017).
5140:38293097
5132:23278562
5090:25101425
5045:21422222
5037:17309706
4978:33155461
4929:17195420
4894:17164106
4861:(5): 20.
4827:10551876
4819:20513829
4784:17411800
4776:20425210
4741:24025657
4703:Chang HY
4686:28 March
4654:20083827
4605:33903526
4597:29239947
4401:33688569
4393:22874090
4358:45682942
4350:24728110
4315:27174075
4213:29170927
4205:29779791
4143:59306658
4135:30689206
4071:19911432
4029:30523705
3980:23240921
3939:30790634
3903:19895534
3895:16404678
3858:29 April
3837:22933756
3829:19255840
3794:17558718
3745:30270423
3693:30939227
3644:32794606
3590:10332663
3582:21612868
3488:22680627
3434:58951422
3426:30670248
3390:53208319
3382:30404055
3347:15246341
3312:17256025
3280:24552444
3272:16480828
3237:15246338
3202:22767485
3194:17309707
3159:31662383
3119:BMJ Open
3094:Testbook
3076:18425909
3027:17909210
2986:31335709
2956:Medicine
2937:19174438
2888:17133529
2840:22124038
2798:20042705
2749:31773455
2703:29187140
2695:29207885
2610:28436583
2558:30178503
2519:29371112
2470:26987082
2412:54472064
2404:30526011
2368:31517832
2338:Medicine
2319:39024642
2311:16492632
2104:10683246
2021:See also
2005:and the
1772:(IASP).
1758:algology
1668:ketamine
1662:Ketamine
1595:naproxen
1521:Tramadol
1509:Fentanyl
1497:Morphine
1351:tramadol
1274:Fentanyl
1246:Morphine
1211:tramadol
1209:such as
1055:opioids
1019:opioids
962:triptans
954:migraine
938:headache
880:template
866:Buddhism
818:hypnosis
812:Hypnosis
687:ablation
628:adjuncts
585:such as
300:injuries
265:dentists
167:medicine
78:Medicine
7590:Outline
7560:Commons
7505:Therapy
7402:Medical
6965:Allergy
6933:Urology
6826:Surgery
6459:(joint)
6251:3845222
5816:4843483
5793:Bibcode
5757:5845507
5714:28 July
5683:2243924
5603:5807105
5554:6175326
5453:8830379
5279:7689093
4732:3845222
4645:3000551
4533:Opioids
4020:6437625
3785:2752362
3736:6257251
3684:6445568
3635:7437545
3547:2967314
3150:6830679
3067:9044120
2977:6709064
2928:2769056
2601:5461882
2510:6020029
2461:6390846
2359:6750337
1892:massage
1587:aspirin
1451:opioids
1435:capsule
1403:Opioids
1393:opiates
1355:codeine
1299:ampules
1248:is the
1219:Vicodin
1115:antacid
974:NSAIDs
893:
693:or the
632:therapy
595:Photons
485:Pilates
477:tai chi
440:opioids
195:chronic
136:clinics
117:(MBChB)
7580:Portal
7447:MD–PhD
6317:
6298:
6275:
6258:
6248:
6213:
6194:
6175:
6156:
6135:
6106:
6098:
6017:
6009:
5974:
5966:
5864:
5823:
5813:
5764:
5754:
5681:
5673:
5610:
5600:
5561:
5551:
5512:
5468:
5460:
5450:
5381:
5330:
5286:
5276:
5236:
5228:
5182:
5138:
5130:
5088:
5078:
5043:
5035:
4976:
4937:408226
4935:
4927:
4892:
4825:
4817:
4782:
4774:
4739:
4729:
4652:
4642:
4603:
4595:
4442:
4399:
4391:
4356:
4348:
4313:
4211:
4203:
4141:
4133:
4069:
4027:
4017:
3978:
3937:
3901:
3893:
3835:
3827:
3792:
3782:
3743:
3733:
3691:
3681:
3642:
3632:
3588:
3580:
3545:
3486:
3432:
3424:
3388:
3380:
3345:
3310:
3278:
3270:
3235:
3200:
3192:
3157:
3147:
3074:
3064:
3025:
2984:
2974:
2935:
2925:
2886:
2838:
2796:
2755:
2747:
2701:
2693:
2608:
2598:
2556:
2517:
2507:
2468:
2458:
2410:
2402:
2366:
2356:
2317:
2309:
2274:26 May
2219:
2194:
2162:
2133:
2102:
1999:AOABOS
1993:, the
1918:, and
1904:coping
1882:, and
1754:Turkey
1750:Greece
1593:, and
1431:tablet
1419:Opioid
1391:While
1361:, and
1309:, and
1232:trauma
1207:opioid
1028:strain
992:sprain
984:bruise
944:NSAIDs
707:labour
326:, and
277:trauma
263:, and
261:nurses
105:(D.O.)
99:(M.D.)
7162:Other
6577:Other
6478:Acute
6104:S2CID
6015:S2CID
5972:S2CID
5925:(PDF)
5918:(PDF)
5671:JSTOR
5466:S2CID
5234:S2CID
5136:S2CID
5095:3 May
5041:S2CID
4933:S2CID
4823:S2CID
4780:S2CID
4601:S2CID
4528:(PDF)
4397:S2CID
4354:S2CID
4209:S2CID
4139:S2CID
3899:S2CID
3833:S2CID
3586:S2CID
3430:S2CID
3386:S2CID
3276:S2CID
3198:S2CID
2753:S2CID
2699:S2CID
2408:S2CID
2315:S2CID
2044:chart
1981:, or
1894:, or
1762:algos
1605:Some
1150:pain
1093:pain
1006:wound
878:‹The
308:dying
191:acute
52:Names
6594:Back
6403:Neck
6372:Pain
6315:ISBN
6296:ISBN
6273:ISBN
6256:PMID
6211:ISBN
6192:ISBN
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