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where the reactant is a nucleophile rather than an electrophile. The four possible electrophilic aliphatic substitution reaction mechanisms are
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83:, usually hydrogen, is replaced by an electrophile. The most important reactions of this type that take place are
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and a positively charged organic residue. The carbanion then quickly recombines with the electrophile. The S
49:, which is typically, but not always, aromatic. Aromatic substitution reactions are characteristic of
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compounds, an electrophile displaces a functional group. This reaction is similar to
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lectrophilic), which are also similar to the nucleophile counterparts
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compounds and are common ways of introducing functional groups into
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in which the old bond and the newly formed bond are both present.
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compounds can undergo electrophilic substitution as well.
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1 course of action the substrate first ionizes into a
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Electrophilic aliphatic substitution reactions are:
103:. It further consists of alkylation and acylation.
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14:
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225:Carbonyl alpha-substitution reactions
107:Electrophilic aliphatic substitution
31:Electrophilic substitution reactions
117:nucleophilic aliphatic substitution
71:Electrophilic aromatic substitution
65:Electrophilic aromatic substitution
24:
18:Electrophilic substitution reaction
187:2 reaction mechanism has a single
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267:
111:In electrophilic substitution in
75:In electrophilic substitution in
13:
1:
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214:Aliphatic diazonium coupling
7:
10:
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239:Advanced Organic Chemistry
79:, an atom appended to the
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221:insertion into C-H bonds
101:Friedel-Crafts reactions
256:Substitution reactions
241:(5th ed.). Wiley.
237:March, Jerry (1985).
209:Keto-enol tautomerism
89:aromatic halogenation
93:aromatic sulfonation
204:Ketone halogenation
85:aromatic nitration
77:aromatic compounds
35:chemical reactions
27:Chemical reaction
16:(Redirected from
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189:transition state
43:functional group
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99:and alkylating
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69:Main article:
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81:aromatic ring
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155:ubstitution
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57:rings. Some
41:displaces a
39:electrophile
37:in which an
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199:Nitrosation
143:(back) and
231:References
175:. In the S
181:carbanion
135:(front),
113:aliphatic
97:acylation
59:aliphatic
250:Category
51:aromatic
47:compound
219:Carbene
55:benzene
45:in a
167:and
95:and
33:are
252::
127:,
91:,
87:,
185:E
177:E
173:2
171:N
169:S
165:1
163:N
161:S
157:E
153:S
151:(
149:i
147:E
145:S
141:2
139:E
137:S
133:2
131:E
129:S
125:1
123:E
121:S
20:)
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