Knowledge

Viremia

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Primary viremia refers to the initial spread of virus in the blood from the first site of infection. Secondary viremia occurs when primary viremia has resulted in infection of additional tissues via bloodstream, in which the virus has replicated and once more entered the circulation.
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Cerino A, Bissolati M, Cividini A, Nicosia A, Esumi M, Hayashi N, Mizuno K, Slobbe R, Oudshoorn P, Silini E, Asti M, Mondelli MU (Jan 1997). "Antibody responses to the hepatitis C virus E2 protein: relationship to viraemia and prevalence in anti-HCV seronegative subjects".
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and viral loads within the bloodstream due to the possibility that the virus is able to reach its natural host cell from the bloodstream and replicate more efficiently than the initial site. An excellent example to profile this distinction is the
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Burrell CJ, Howard CR, Murphy FA (2017-01-01), Burrell CJ, Howard CR, Murphy FA (eds.), "Chapter 7 - Pathogenesis of Virus Infections",
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Passive viremia is the introduction of viruses in the bloodstream without the need of active viral replication. Examples include direct
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is unstoppable. Vaccination must be done before secondary viremia takes place for the individual to avoid brain damage or death.
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tissues. Viral replication then leads to viremia and the virus spreads to its secondary site of infection, the
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Active viremia is caused by the replication of viruses which results in viruses being introduced into the
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enter the bloodstream. The name comes from combining the word "virus" with the Greek word for "blood" (
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Mulupuri P, Zimmerman JJ, Hermann J, Johnson CR, Cano JP, Yu W, Dee SA, Murtaugh MP (2007-12-10).
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virus. Usually the virus will replicate briefly within the first site of infection, within the
841: 689: 311:"Viral RNA in the bloodstream suggests viremia occurs in clinically ill rabies-infected mice" 836: 8: 809: 669: 641: 612: 594: 523: 381: 118:(CNS). Upon infection of the CNS, secondary viremia results and symptoms usually begin. 897: 694: 462: 437: 413: 376: 259: 240: 174: 528: 923: 655: 551: 467: 418: 400: 357: 330: 291: 244: 211: 51: 754: 744: 723: 457: 449: 408: 390: 326: 322: 283: 254: 236: 792: 627: 617: 539: 436:
Lai CJ, Goncalvez AP, Men R, Wernly C, Donau O, Engle RE, Purcell RH (Dec 2007).
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10.1002/(sici)1096-9071(199701)51:1<1::aid-jmv1>3.3.co;2-3
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and hence have access to the rest of the body. It is similar to
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Gribencha SV, Barinsky IF (Jul 1982). "Viraemia in rabies".
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layer (viral shedding), resulting in viruses budding into
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tract before replicating and budding out of the cell
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Abnormal clinical and laboratory findings for blood
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Fenner and White's Medical Virology (Fifth Edition)
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Examples include the 854:Bloodstream infections 823:Sabin–Feldman dye test 738:Warthin–Finkeldey cell 116:central nervous system 130:Active versus passive 837:Diagnosis of malaria 454:10.1128/jvi.01420-07 396:10.1128/JVI.01023-07 81:, a condition where 810:Protozoan infection 670:Anti-streptolysin O 613:rapid plasma reagin 595:Bacterial infection 382:Journal of Virology 898:C-reactive protein 707:Epstein–Barr virus 695:Branched DNA assay 587:infectious disease 175:blood transfusions 57:Infectious disease 911: 910: 656:HelicoCARE direct 549: 548: 250:978-0-12-375156-0 217:978-0-8385-8529-0 62: 61: 32:Medical condition 16:(Redirected from 936: 842:SchĂĽffner's dots 755:B type inclusion 745:Inclusion bodies 724:NS1 antigen test 576: 569: 562: 553: 552: 488: 487: 476: 475: 465: 448:(23): 12766–74. 433: 427: 426: 416: 398: 372: 366: 365: 345: 339: 338: 306: 300: 299: 270: 264: 263: 262: 228: 222: 221: 203: 35: 34: 21: 944: 943: 939: 938: 937: 935: 934: 933: 914: 913: 912: 907: 886: 848: 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1–5. 193:References 187:Septicemia 171:mosquitoes 144:epithelial 78:bacteremia 71:enter the 405:0022-538X 52:Specialty 924:Virology 882:Algaemia 872:Fungemia 603:syphilis 472:17881450 423:17942527 335:16242805 181:See also 83:bacteria 46:Viraemia 18:Viraemia 891:General 867:Viremia 831:malaria 732:measles 540:D014766 463:2169078 442:J Virol 414:2224379 362:6127940 296:8986942 260:7150039 140:measles 69:viruses 65:Viremia 38:Viremia 768:rabies 470:  460:  421:  411:  403:  360:  333:  294:  257:  247:  214:  112:muscle 108:rabies 700:mChip 529:790.8 514:B34.9 169:from 152:basal 124:brain 87:haima 585:for 535:MeSH 524:9-CM 468:PMID 419:PMID 401:ISSN 358:PMID 331:PMID 292:PMID 245:ISBN 212:ISBN 158:and 520:ICD 505:ICD 458:PMC 450:doi 409:PMC 391:doi 323:doi 319:116 284:doi 255:PMC 237:doi 920:: 538:: 527:: 512:: 509:10 466:. 456:. 446:81 444:. 440:. 417:. 407:. 399:. 387:82 385:. 379:. 354:26 352:. 329:. 313:. 290:. 280:51 278:. 253:, 243:, 177:. 162:. 575:e 568:t 561:v 522:- 507:- 497:D 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Index

Viraemia
Specialty
Infectious disease
viruses
bloodstream
bacteremia
bacteria
viral shedding
rabies
muscle
central nervous system
Vaccination
brain
bloodstream
measles
epithelial
respiratory
basal
capillaries
blood vessels
inoculation
mosquitoes
blood transfusions
Septicemia
ISBN
978-0-8385-8529-0
doi
10.1016/b978-0-12-375156-0.00007-2
ISBN
978-0-12-375156-0

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