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Transition (genetics)

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27: 499: 244:"Genetic Divergence and Evolutionary Transition/Transversion Rate Bias in the Control Region of Mitochondrial DNA of Palearctic Mice (Murinae)" 540: 30:
Illustration of a transition: each of the 4 nucleotide changes between purines or between pyrimidines (in blue). The 8 other changes are
158:
Collins DW, Jukes TH (April 1994). "Rates of transition and transversion in coding sequences since the human-rodent divergence".
319: 533: 81: 564: 20: 526: 478: 428: 292: 108: 103:, possibly due to the molecular mechanisms that generate them. Transitions are more likely to be 473: 104: 514: 312: 433: 397: 88: 342: 8: 407: 347: 468: 458: 453: 271: 219: 194: 559: 392: 387: 305: 275: 263: 224: 175: 46: 26: 463: 412: 255: 214: 206: 167: 114: 402: 92: 510: 379: 50: 259: 553: 267: 96: 31: 243: 506: 355: 228: 171: 138: 179: 126: 122: 195:"Genomewide comparison of DNA sequences between humans and chimpanzees" 69: 57: 328: 210: 118: 73: 42: 77: 65: 61: 125:. This mechanism is important because it dictates the rarity of 100: 54: 192: 498: 297: 193:
Ebersberger I, Metzler D, Schwarz C, Pääbo S (June 2002).
241: 242:
Mezhzherin, S. V.; Tereshchenko, V. O. (2023-06-01).
551: 117:is more prone to transition than unmethylated 534: 313: 157: 95:. Although there are twice as many possible 107:than transversions, as one observes in the 16:DNA mutation that exchanges two nucleotides 541: 527: 320: 306: 218: 447:Mutation with respect to overall fitness 25: 552: 301: 493: 99:, transitions appear more often in 13: 372:Mutation with respect to structure 80:). Approximately two out of three 72:nucleotide to another pyrimidine ( 14: 576: 286: 497: 82:single nucleotide polymorphisms 235: 186: 151: 1: 144: 87:Transitions can be caused by 513:. You can help Knowledge by 327: 7: 132: 10: 581: 492: 429:Chromosomal translocations 18: 446: 421: 378: 371: 335: 260:10.3103/S0095452723030076 105:synonymous substitutions 84:(SNPs) are transitions. 469:Nearly neutral mutation 479:Nonsynonymous mutation 434:Chromosomal inversions 336:Mechanisms of mutation 172:10.1006/geno.1994.1192 35: 459:Advantageous mutation 398:Conservative mutation 248:Cytology and Genetics 121:, due to spontaneous 89:oxidative deamination 29: 454:Deleterious mutation 422:Large-scale mutation 19:For other uses, see 474:Synonymous mutation 408:Frameshift mutation 60:to another purine ( 565:Cell biology stubs 36: 522: 521: 487: 486: 442: 441: 393:Missense mutation 388:Nonsense mutation 293:Diagram at mun.ca 199:Am. J. Hum. Genet 47:molecular biology 572: 543: 536: 529: 501: 494: 464:Neutral mutation 413:Dynamic mutation 376: 375: 322: 315: 308: 299: 298: 280: 279: 239: 233: 232: 222: 190: 184: 183: 155: 115:5-Methylcytosine 580: 579: 575: 574: 573: 571: 570: 569: 550: 549: 548: 547: 490: 488: 483: 438: 417: 403:Silent mutation 367: 331: 326: 289: 284: 283: 240: 236: 191: 187: 156: 152: 147: 135: 93:tautomerization 53:that changes a 24: 17: 12: 11: 5: 578: 568: 567: 562: 546: 545: 538: 531: 523: 520: 519: 502: 485: 484: 482: 481: 476: 471: 466: 461: 456: 450: 448: 444: 443: 440: 439: 437: 436: 431: 425: 423: 419: 418: 416: 415: 410: 405: 400: 395: 390: 384: 382: 380:Point mutation 373: 369: 368: 366: 365: 364: 363: 358: 350: 345: 339: 337: 333: 332: 325: 324: 317: 310: 302: 296: 295: 288: 287:External links 285: 282: 281: 254:(3): 213–220. 234: 211:10.1086/340787 185: 149: 148: 146: 143: 142: 141: 134: 131: 51:point mutation 49:, refers to a 15: 9: 6: 4: 3: 2: 577: 566: 563: 561: 558: 557: 555: 544: 539: 537: 532: 530: 525: 524: 518: 516: 512: 509:article is a 508: 503: 500: 496: 495: 491: 480: 477: 475: 472: 470: 467: 465: 462: 460: 457: 455: 452: 451: 449: 445: 435: 432: 430: 427: 426: 424: 420: 414: 411: 409: 406: 404: 401: 399: 396: 394: 391: 389: 386: 385: 383: 381: 377: 374: 370: 362: 359: 357: 354: 353: 352:Substitution 351: 349: 346: 344: 341: 340: 338: 334: 330: 323: 318: 316: 311: 309: 304: 303: 300: 294: 291: 290: 277: 273: 269: 265: 261: 257: 253: 249: 245: 238: 230: 226: 221: 216: 212: 208: 205:(6): 1490–7. 204: 200: 196: 189: 181: 177: 173: 169: 166:(3): 386–96. 165: 161: 154: 150: 140: 137: 136: 130: 128: 124: 120: 116: 112: 110: 106: 102: 98: 97:transversions 94: 90: 85: 83: 79: 75: 71: 67: 63: 59: 56: 52: 48: 44: 40: 33: 32:transversions 28: 22: 515:expanding it 507:cell biology 504: 489: 360: 356:Transversion 251: 247: 237: 202: 198: 188: 163: 159: 153: 139:Transversion 113: 86: 38: 37: 127:CpG islands 123:deamination 109:codon table 554:Categories 361:Transition 145:References 70:pyrimidine 58:nucleotide 39:Transition 21:Transition 343:Insertion 276:259191096 268:1934-9440 34:(in red). 560:Mutation 348:Deletion 329:Mutation 229:11992255 160:Genomics 133:See also 119:cytosine 68:), or a 43:genetics 180:8034311 101:genomes 274:  266:  227:  220:379137 217:  178:  55:purine 505:This 272:S2CID 41:, in 511:stub 264:ISSN 225:PMID 176:PMID 91:and 45:and 256:doi 215:PMC 207:doi 168:doi 556:: 270:. 262:. 252:57 250:. 246:. 223:. 213:. 203:70 201:. 197:. 174:. 164:20 162:. 129:. 111:. 76:↔ 64:↔ 542:e 535:t 528:v 517:. 321:e 314:t 307:v 278:. 258:: 231:. 209:: 182:. 170:: 78:T 74:C 66:G 62:A 23:.

Index

Transition

transversions
genetics
molecular biology
point mutation
purine
nucleotide
A
G
pyrimidine
C
T
single nucleotide polymorphisms
oxidative deamination
tautomerization
transversions
genomes
synonymous substitutions
codon table
5-Methylcytosine
cytosine
deamination
CpG islands
Transversion
doi
10.1006/geno.1994.1192
PMID
8034311
"Genomewide comparison of DNA sequences between humans and chimpanzees"

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