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adverse effects. Tolerability, however, is often relative to the severity of the medical condition a drug is designed to treat. For instance, cancer patients may tolerate significant pain or discomfort during a chemotherapeutic study with the hope of prolonging survival or finding a cure, whereas patients experiencing a benign condition, such as a headache, are less likely to.
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of a drug can be tolerated by a patient. Tolerability of a particular drug can be discussed in a general sense, or it can be a quantifiable measurement as part of a clinical study. Usually, it is measured by the rate of "dropouts", or patients that forfeit participation in a study due to extreme
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effects, whereas newer antidepressants have far fewer adverse effects and are well tolerated.
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136:(TCAs) are very poorly tolerated and often produce severe side effects including
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Degree to which overt adverse effects of a drug can be tolerated by a patient
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Ton, Nu Thanh Huyen; Hartstra, Jan; Persiani, Stefano; Beckert, Michael.
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1833:Antimicrobial pharmacodynamics
881:Doctor of Osteopathic Medicine
315:Oral and maxillofacial surgery
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1891:. You can help Knowledge by
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628:Neurosurgical anesthesiology
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1149:Irreversible antagonist
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189:"Safety - Tolerability"
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1887:-related article is a
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43:improve this article
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195:. David W.A. Bourne
1943:Pharmacology stubs
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1893:expanding it
1885:pharmacology
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1768:Chemotherapy
1728:Cell biology
1629:Biochemistry
1553:Neuroscience
1501:Distribution
1431:Loading dose
1114:Superagonist
1071:Pharmacology
939:Rural health
924:Nanomedicine
475:Rheumatology
406: /
325:Hand surgery
310:Neurosurgery
197:. Retrieved
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122:Tolerability
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41:Please help
36:verification
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1853:Bactericide
1529:Compartment
1340:Patch clamp
1316:Schild plot
1009:Wikiproject
798:Venereology
743:Neonatology
640:Dermatology
495:Gynaecology
487:gynaecology
470:Pulmonology
288:Eye surgery
250:Specialties
199:13 November
165:Side effect
1932:Categories
1733:Physiology
1665:Toxicology
1557:psychology
1506:Metabolism
1496:Absorption
1490:Liberation
1332:Organ bath
1260:Functional
1139:Antagonist
1132:Inhibitory
1087:Excitatory
771:Psychiatry
757:(PM&R)
750:Phlebology
738:Pediatrics
565:Anatomical
530:Diagnostic
510:Obstetrics
460:Nephrology
445:Hematology
440:Geriatrics
433:Hepatology
418:Cardiology
408:Immunology
171:References
69:newspapers
1515:Clearance
1511:Excretion
1330:Methods (
959:Physician
843:education
701:Neurology
696:Narcology
560:Pathology
538:Radiology
413:Angiology
377:Andrology
1633:genetics
1605:Pharmacy
1592:Medicine
1402:Affinity
1361:Efficacy
1299:Analysis
1281:Toxicity
989:Category
465:Oncology
396:medicine
394:Internal
242:Medicine
159:See also
138:sedation
1543:Related
1486:(L)ADME
1440:Initial
1424:Metrics
1371:Potency
1354:Metrics
1256:Binding
1226:Binding
1094:Agonist
1029:Outline
999:Commons
944:Therapy
841:Medical
404:Allergy
372:Urology
265:Surgery
83:scholar
1545:fields
1019:Portal
886:MD–PhD
144:, and
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1883:This
1742:Other
1479:LADME
601:Other
90:JSTOR
76:books
1889:stub
1631:and
1555:and
1391:TD50
1387:LD50
1383:ED50
1379:IC50
1375:EC50
1177:Drug
201:2013
62:news
1488:: (
335:ENT
253:and
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