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3914:
25:
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655:. This often occurs when patients fail to inform their physician and pharmacist of all the medications they are taking, including herbal and dietary supplements. The new medication may interact agonistically or antagonistically (potentiate or decrease the intended therapeutic effect), causing significant
452:
In principle, medical professionals are required to report all adverse effects related to a specific form of therapy. In practice, it is at the discretion of the professional to determine whether a medical event is at all related to the therapy. As a result, routine adverse effects reporting often
430:
in
Dunedin is New Zealand's national monitoring centre for adverse reactions. It collects and evaluates spontaneous reports of adverse reactions to medicines, vaccines, herbal products and dietary supplements from health professionals in New Zealand. Currently the CARM database holds over 80,000
439:
In Canada, adverse reaction reporting is an important component of the surveillance of marketed health products conducted by the Health
Products and Food Branch (HPFB) of Health Canada. Within HPFB, the Marketed Health Products Directorate leads the coordination and implementation of consistent
728:
studies to determine the nonadverse effect level (NOAEL). These studies are used to define the dosage to be used in human testing (phase I), as well as to calculate the maximum admissible daily intake. Imperfections in clinical trials, such as insufficient number of patients or short duration,
410:(ADEC). Reporting is voluntary, and ADRAC requests healthcare professionals to report all adverse reactions to its current drugs of interest, and serious adverse reactions to any drug. ADRAC publishes the Australian Adverse Drug Reactions Bulletin every two months. The Government's
253:
In terms of drugs, adverse events may be defined as: "Any untoward medical occurrence in a patient or clinical investigation subject administered a pharmaceutical product and which does not necessarily have to have a causal relationship with this treatment."
1238:). No link has been found in several large studies, and despite removal of thimerosal from most early childhood vaccines beginning with those manufactured in 2003, the rate of autism has not decreased as would be expected if it had been the causative agent.
280:
The term "life-threatening" in the context of a serious adverse event refers to an event in which the patient was at risk of death at the time of the event; it does not refer to an event which hypothetically might have caused death if it were more severe.
2038:
Kraus MR, Schäfer A, Schöttker K, Keicher C, Weissbrich B, Hofbauer I, Scheurlen M (April 2008). "Therapy of interferon-induced depression in chronic hepatitis C with citalopram: a randomised, double-blind, placebo-controlled study".
500:. They can be reversible or irreversible, and a compromise must be found by the physician and the patient between the beneficial or life-saving consequences of surgery versus its adverse effects. For example, a limb may be lost to
309:
and meta-analyses of therapeutic interventions often unknowingly overemphasise health benefit. To balance the overemphasis on benefit, scholars have called for more complete reporting of harm from clinical trials.
2921:
2906:
443:
MHPD also works closely with international organizations to facilitate the sharing of information. Adverse reaction reporting is mandatory for the industry and voluntary for consumers and health professionals.
305:. Research suggests that these events are often inadequately reported in publicly available reports. Because of the lack of these data and uncertainty about methods for synthesising them, individuals conducting
173:
is similar to adverse effect, but the latter is typically used in pharmacological contexts, or when the negative effect is expected or common. If the negative effect results from an unsuitable or incorrect
3395:
780:
Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects, which have a widely variable incidence according to individual sensitivity, include
431:
reports and provides New
Zealand-specific information on adverse reactions to these products, and serves to support clinical decision making when unusual symptoms are thought to be therapy related
1458:"Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013"
1560:
1507:
277:
is considered a serious adverse event. The results of trials are often included in the labelling of the medication to provide information both for patients and the prescribing physicians.
237:
reported by a patient. Adverse effects may cause a reversible or irreversible change, including an increase or decrease in the susceptibility of the individual to other chemicals,
1561:
Expert working group (efficacy) of the international conference on harmonization of technical requirements for registration of pharmaceuticals for human use (August 25, 2007).
1508:
Expert
Working Group (Efficacy) of the International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (March 1995).
2150:
1914:
3256:
2779:
1435:
809:, dry mouth, etc. These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.
2564:
Reid R (December 2010). "SOGC clinical practice guideline. No. 252, December 2010. Oral contraceptives and the risk of venous thromboembolism: an update".
2679:
Fialip J, Aumaitre O, Eschalier A, Maradeix B, Dordain G, Lavarenne J (December 1987). "Benzodiazepine withdrawal seizures: analysis of 48 case reports".
2371:
2810:
2314:
1248:, which led to class actions brought by tens of thousands of plaintiffs against manufacturers of gel-based implants, due to allegations of damage to the
716:
The scientific field of activity associated with drug safety is increasingly government-regulated, and is of major concern for the public, as well as to
327:
190:/treatment. Some adverse effects occur only when starting, increasing or discontinuing a treatment. Using a drug or other medical intervention which is
350:
and unlicensed medicines found in cosmetic treatments. Adverse drug reactions (ADRs) can be reported by a number of health care professionals including
3161:
816:) warns that people with dementia are more likely to experience adverse effects, and that they are less likely to be able to reliably report symptoms.
3964:
2985:– MedWatch lists safety alerts for drugs, biologics, devices and dietary supplements, recalls, market withdrawals, public health advisories and links
1676:, O'Neill RT, Altman DG, Schulz K, Moher D (November 2004). "Better reporting of harms in randomized trials: an extension of the CONSORT statement".
440:
monitoring practices with regards to assessment of signals and safety trends, and risk communications concerning regulated marketed health products.
1288:
2723:
2082:
1846:
1799:"Medication appropriateness tool for co-morbid health conditions in dementia: consensus recommendations from a multidisciplinary expert panel"
3249:
3113:
382:(VAERS), the Manufacturer and User Facility Device Experience Database (MAUDE) and the Special Nutritionals Adverse Event Monitoring System.
2976:
1539:
387:
1944:
1252:
which have not yet been conclusively proven. In 1998, Dow
Corning settled its remaining suits for $ 3.2 Billion and went into bankruptcy.
210:
with a treatment regimen. Adverse effects of medical treatment resulted in 142,000 deaths in 2013 up from 94,000 deaths in 1990 globally.
2866:
2340:
843:(Cytotec), a labor-inducing drug (this is a case where the adverse effect has been used legally and illegally for performing abortions)
2994:
2657:
403:
3242:
3222:
2219:
3166:
2972:
2460:
Patten SB, Neutel CI (February 2000). "Corticosteroid-induced adverse psychiatric effects: incidence, diagnosis and management".
1260:
2288:
3026:
2434:
1188:
720:. The distinction between adverse and nonadverse effects is a major undertaking when a new drug is developed and tested before
379:
2512:
1966:
3957:
3415:
2832:
89:
1906:
414:
program is tasked with acting on this reporting to reduce and minimize the number of preventable adverse effects each year.
1267:, have led to public outcry and changes in medical therapy, although its benefits largely surpassed the statistical risks.
407:
61:
2745:
2120:
1884:
1513:
4175:
3732:
3420:
2542:
2142:
1569:
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Sometimes, putative medical adverse effects are regarded as controversial and generate heated discussions in society and
2775:
3525:
2991:
National
Library of Medicine (Medline Plus, useful lists of conventional drug and medical device articles and websites)
1586:
Ioannidis JP, Lau J (2001). "Completeness of safety reporting in randomized trials: an evaluation of 7 medical areas".
620:
Adverse effects can occur as a collateral or side effect of many interventions, but they are particularly important in
1391:
659:
and mortality around the world. Drug-drug and food-drug interactions may occur, and so-called "natural drugs" used in
68:
702:
108:
3950:
3518:
1314:
1112:
331:
2310:
2961:
2958:– includes a glossary and articles on adverse effects, drug reactions, medical error, iatrogenesis, among others.
2241:
Tripathi RC, Parapuram SK, Tripathi BJ, Zhong Y, Chalam KV (December 1999). "Corticosteroids and glaucoma risk".
1263:, which may affect millions of users, even marginal probabilities of adverse effects of a severe nature, such as
464:, death is a very likely outcome and whether the drug is the cause or a bystander is often difficult to discern.
460:
may be caused by the underlying disease or may be an adverse effect of the treatment. In patients with end-stage
42:
75:
4165:
2363:
456:
Part of the difficulty is identifying the source of a complaint. A headache in a patient taking medication for
46:
4099:
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3156:
1510:"Guideline for Industry – Clinical safety data management: definitions and standards for expedited reporting"
4160:
4079:
3742:
3551:
583:
509:
57:
1719:
Bailey, C; Peddie, D; Wickham, ME; Badke, K; Small, SS; Doyle-Waters, MM; Balka, E; Hohl, CM (July 2016).
3390:
3192:
3187:
2998:
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for sale to the public. Investigators in human clinical trials are obligated to report these events in
2988:
4024:
3894:
3627:
3535:
3440:
3430:
3333:
676:
560:
and local reactions in the vaccination site. Very rarely, there is a serious adverse effect, such as
2090:
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change detected at the microscopic, macroscopic or physiological level. It may also be indicated by
3809:
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3340:
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2833:"Silicone Breast Implants in Relation to Connective Tissue Diseases and Immunologic Dysfunction"
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Chou R, Helfand M (June 2005). "Challenges in systematic reviews that assess treatment harms".
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and elimination of many drugs, so patients taking it are likely to experience a reduction in
615:
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may not include long-term and subtle effects that may ultimately be attributed to a therapy.
343:
302:
266:
207:
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may have adverse effects due to the nature of its biological preparation, sometimes using
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use. Some antihistamines are used in sleep aids explicitly because they cause drowsiness.
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270:
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1769:"MATCH-D Medication Appropriateness Tool for Comorbid Health conditions during Dementia"
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Due to the exceedingly high impact on public health of widely used medications, such as
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In many countries, adverse effects are required by law to be reported, researched in
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against drug manufacturers. One example is the recent controversy as to whether
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The
Medication Appropriateness Tool for Comorbid Health Conditions in Dementia (
508:, but the patient's life is saved. Presently, one of the greatest advantages of
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Eosinophilic, polymorphic, and pruritic eruption associated with radiotherapy
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Page AT, Potter K, Clifford R, McLachlan AJ, Etherton-Beer C (October 2016).
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procedures may also have adverse effects, depending much on whether they are
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and not an adverse effect. Adverse effects are sometimes referred to as "
162:
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1563:"Guideline for Industry Structure and Content of Clinical Study Reports"
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Harmful effect resulting from a medication or other medical intervention
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Tapiainen T, Heininger U (June 2005). "Fever following immunization".
1814:
1736:
1532:"Reporting Serious Problems to FDA - What is a Serious Adverse Event?"
773:, and a significant number of deaths, causing the forced or voluntary
644:, so they may be avoided or decreased by means of careful and precise
422:
Adverse reaction reporting is an important component of New
Zealand's
3851:
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3350:
1282:
1076:
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937:
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786:
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Mokrzycki MH, Harris C, May H, Laut J, Palmisano J (January 2000).
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338:. This includes all licensed medicines, from medicines issued on
234:
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198:
of adverse effects. Adverse effects may cause complications of a
158:
2218:. Centers for Disease Control and Prevention (CDC). 2018-07-12.
1392:"Adverse drug reactions: definitions, diagnosis, and management"
624:, due to its wider, and sometimes uncontrollable, use by way of
213:
The harmful outcome is usually indicated by some result such as
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1013:
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2240:
753:(Vioxx), where drastic adverse effects were observed, such as
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Other nonsurgical physical procedures, such as high-intensity
2967:
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2285:"Chemotherapy and hair loss: What to expect during treatment"
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979:
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can have dangerous adverse effects. For example, extracts of
553:
549:
531:. In general, these therapies try to avoid damage to healthy
480:
may have a number of undesirable or harmful effects, such as
359:
269:. Generally, any event which causes death, permanent damage,
218:
2037:
694:
levels of drugs they are taking for other purposes, such as
3287:
1796:
1721:"Adverse drug event reporting systems: a systematic review"
528:
524:
493:
298:
238:
195:
2955:
1995:
Bray RJ (1998). "Propofol infusion syndrome in children".
328:
Medicines and
Healthcare products Regulatory Agency (MHRA)
1072:
706:
2598:
1907:"Even Low Dose of Aspirin Can Cause Intestinal Bleeding"
1718:
632:
becomes an important issue here. Adverse effects, like
378:
several reporting systems have been built, such as the
293:
and included into the patient information accompanying
2392:
1877:"Morphine Addiction Withdrawal Symptoms and Treatment"
1529:
2364:"What Are the Side Effects of Adults Taking Ritalin?"
1390:
Edwards, I. Ralph; Aronson, Jeffrey K. (2000-10-07).
1241:
Another instance is the potential adverse effects of
819:
2888:
3264:
49:. Unsourced material may be challenged and removed.
3162:Political abuse of psychiatry in the United States
2311:"Headache After an Epidural or Spinal Anaesthetic"
2171:
402:,adverse effect reporting is administered by the
346:from a supermarket. The scheme also includes all
4152:
2599:Wills BK, Albinson C, Wahl M, Clifton J (2007).
2143:"Can anti-depressants cause sexual dysfunction?"
1289:Classification of Pharmaco-Therapeutic Referrals
149:is an undesired harmful effect resulting from a
1643:10.7326/0003-4819-142-12_part_2-200506211-00009
1568:. FDA Center for Drug Evaluation and Research.
1512:. FDA Center for Drug Evaluation and Research.
1389:
1183:, increased tendency associated to the use of
428:Centre for Adverse Reactions Monitoring (CARM)
386:is the main reporting center, operated by the
3958:
3250:
3114:Prescription drug prices in the United States
3020:
2566:Journal of Obstetrics and Gynaecology Canada
2459:
2361:
2113:"Xenical and Diarrhea: a study of 591 users"
1585:
334:to gather information on adverse effects to
165:", when judged to be secondary to a main or
3972:
2778:. U.S. Food and Drug Administration (FDA).
1847:"Mifepristone and Misoprostol for Abortion"
1628:
1107:associated with use of estrogen-containing
3965:
3951:
3901:
3257:
3243:
3027:
3013:
2962:Australian Adverse Drug Reactions Bulletin
2800:
2647:
2746:"Metoclopramide & Tardive Dyskinesia"
2616:
2410:
1822:
1744:
1481:
535:while maximizing the therapeutic effect.
404:Adverse Drug Reactions Advisory Committee
109:Learn how and when to remove this message
1725:British Journal of Clinical Pharmacology
1690:10.7326/0003-4819-141-10-200411160-00009
1039:users, which prompted FDA to remove the
496:, loss of function, or changes in local
3167:Political abuse of psychiatry in Russia
2502:
2123:from the original on September 20, 2011
516:, is the reduction of adverse effects.
202:or procedure and negatively affect its
4153:
2726:from the original on December 28, 2023
2374:from the original on February 18, 2013
1503:
1501:
1449:
1189:selective serotonin reuptake inhibitor
679:are known to cause an increase in the
651:Adverse effects may also be caused by
380:Vaccine Adverse Event Reporting System
3946:
3416:Radiation-induced erythema multiforme
3238:
3008:
2713:
2435:"Metformin and Fatal Lactic Acidosis"
2337:"Ephedra (Ephedra sinica) / ma huang"
2291:from the original on February 5, 2013
2216:"Possible Side-effects from Vaccines"
472:
161:. An adverse effect may be termed a "
3889:
2995:When Medicine Hurts Instead of Helps
2859:"Breast Implant Litigation Timeline"
2782:from the original on January 6, 2013
2563:
1994:
1542:from the original on 25 January 2018
973:associated with many drugs, such as
408:Australian Drug Evaluation Committee
284:
47:adding citations to reliable sources
18:
3733:Pseudoverrucous papules and nodules
3421:Radiation-induced hypertrophic scar
2813:from the original on March 20, 2013
2545:from the original on March 27, 2013
2222:from the original on March 17, 2017
2153:from the original on March 21, 2013
1917:from the original on April 20, 2013
1887:from the original on March 18, 2013
1498:
332:Commission on Human Medicines (CHM)
261:, a distinction is made between an
13:
2983:Medical Product Safety Information
2648:Behrenbeck T (December 14, 2012).
2515:from the original on June 26, 2015
2339:. Mayo Clinic. September 1, 2012.
2083:"Diabetes and Antipsychotic Drugs"
1575:from the original on May 25, 2009.
1519:from the original on May 11, 2009.
820:Examples with specific medications
186:" because they are generated by a
14:
4192:
2977:U.S. Food and Drug Administration
2884:
2660:from the original on June 1, 2013
2343:from the original on May 12, 2013
2317:from the original on June 8, 2015
1947:from the original on May 30, 2013
1234:-based preservative used in some
602:may cause the perforation of the
313:
248:
3924:
3912:
3900:
3888:
3877:
3876:
3519:Inner ear decompression sickness
3034:
2968:MedEffect Canada (Health Canada)
2693:10.1097/00002826-198712000-00005
2474:10.2165/00002018-200022020-00004
2255:10.2165/00002512-199915060-00004
2009:10.1046/j.1460-9592.1998.00282.x
1315:List of pharmaceutical companies
1209:
1113:combined oral contraceptive pill
552:. Common adverse effects may be
369:
23:
3913:
3092:Economic and financial concerns
2869:from the original on 2018-06-20
2851:
2825:
2803:"CDC sees autism rate rise 25%"
2794:
2768:
2738:
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2672:
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2303:
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2165:
2135:
2105:
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1988:
1959:
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1869:
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1790:
1779:from the original on 2019-05-18
1761:
1438:from the original on 2012-03-07
467:
406:(ADRAC), a subcommittee of the
178:or procedure, this is called a
34:needs additional citations for
2287:. Mayo Clinic. March 6, 2012.
1712:
1665:
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1579:
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609:
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1:
4100:Rebound effect (conservation)
3753:environmental skin conditions
3546:High-altitude pulmonary edema
3157:Political abuse of psychiatry
2801:Jaslow, R. (March 29, 2012).
2578:10.1016/S1701-2163(16)34746-6
2503:Willacy H (January 4, 2013).
1971:Gentamicin Information Center
1474:10.1016/S0140-6736(14)61682-2
1408:10.1016/S0140-6736(00)02799-9
1376:
777:of the drug from the market.
640:or drug levels at the target
598:materials often occur, and a
4080:Parable of the broken window
3743:Tropical anhidrotic asthenia
3552:High-altitude cerebral edema
2399:Clinical Infectious Diseases
2362:Bergeson, B. (May 6, 2010).
1530:Office of the Commissioner.
733:disasters, such as those of
636:of drugs, are a function of
393:
388:Food and Drug Administration
229:, loss of function, or as a
7:
3765:frictional/traumatic/sports
3391:Chronic radiation keratosis
3193:Hospital-acquired infection
3188:Hospital-acquired pneumonia
2999:Alliance for Aging Research
1678:Annals of Internal Medicine
1631:Annals of Internal Medicine
1270:
1261:hormone replacement therapy
1120:associated with the use of
1067:associated with the use of
10:
4197:
4176:Effects of external causes
4140:Tyranny of small decisions
3857:Pseudoacanthosis nigricans
2997:– June 1998 report by the
2714:Kenny T (April 20, 2011).
2681:Clinical Neuropharmacology
1143:caused by withdrawal from
613:
4025:Excess burden of taxation
3980:
3872:
3709:
3681:
3636:
3628:Space adaptation syndrome
3605:
3579:
3563:
3536:Chronic mountain sickness
3479:
3454:
3441:Radiation recall reaction
3431:Radiation-induced morphea
3383:
3334:Warm water immersion foot
3306:
3280:
3273:
3211:
3175:
3122:
3091:
3040:
2892:
2750:Tardive Dyskinesia Center
2618:10.1080/15563650701664483
2174:Expert Review of Vaccines
1941:Weitz & Luxenberg P.C
1803:Internal Medicine Journal
1174:(Viagra), when used with
953:medications (neuroleptic
434:
241:, or procedures, such as
131:
126:
3810:Weathering nodule of ear
3426:Radiation-induced keloid
3411:Radiation-induced cancer
3341:Non-freezing cold injury
3319:Immersion foot syndromes
3140:Compulsory sterilization
2776:"Thimerosal in Vaccines"
2186:10.1586/14760584.4.3.419
1937:"Coronary Heart Disease"
1672:Ioannidis JP, Evans SJ,
894:disease associated with
412:Quality Use of Medicines
206:. They may also lead to
4110:Self-defeating prophecy
3974:Unintended consequences
3738:Sclerosing lymphangitis
3329:Tropical immersion foot
3068:Unnecessary health care
2505:"Paracetamol Poisoning"
2053:10.1136/gut.2007.131607
1345:Perioperative mortality
1320:List of withdrawn drugs
1310:Evidence-based medicine
1197:associated with use of
745:and, more recently, of
711:hormonal contraceptives
675:used for treating mild
527:and alterations in the
504:in case of untreatable
4135:Tragedy of the commons
3825:Painful fat herniation
3805:Vibration white finger
3514:Decompression sickness
3371:Erythrocyanosis crurum
3135:Sluggish schizophrenia
2989:Medical Devices Safety
2956:Patient Safety Network
1600:10.1001/jama.285.4.437
1257:hormonal contraception
1191:(SSRI) antidepressants
1109:hormonal contraception
1053:caused by stimulants,
951:atypical antipsychotic
759:pulmonary hypertension
749:(Baycol, Lipobay) and
326:initiative run by the
303:clinical study reports
4166:Clinical pharmacology
4085:Paradox of enrichment
3780:Fissure of the nipple
3748:UV-sensitive syndrome
3673:Adverse drug reaction
3502:Middle ear barotrauma
3492:Arterial gas embolism
3212:Records and histories
3183:Adverse drug reaction
3151:The Protest Psychosis
2964:– published bimonthly
1295:Consultant pharmacist
1278:Adverse drug reaction
963:caused by the use of
616:Adverse drug reaction
267:serious adverse event
4055:Inverse consequences
3775:Equestrian perniosis
1997:Pediatric Anesthesia
1913:. November 9, 2000.
1330:Medical prescription
971:Erectile dysfunction
926:, in children using
724:it. This is done in
686:responsible for the
669:Hypericum perforatum
661:alternative medicine
630:responsible drug use
514:laparoscopic surgery
342:to medicines bought
43:improve this article
4161:Medical terminology
4030:Four Pests campaign
3862:Narcotic dermopathy
3770:Black heel and palm
3723:Dermatosis neglecta
3597:Psychological abuse
3436:Radiation poisoning
3053:Medical malpractice
2605:Clinical Toxicology
1637:(12 Pt 2): 1090–9.
1402:(9237): 1255–1259.
703:protease inhibitors
634:therapeutic effects
4115:Self-refuting idea
4095:Perverse incentive
3832:Uranium dermatosis
3785:Pulling boat hands
3694:Lightning injuries
3109:Financial toxicity
2535:"What is Melasma?"
1773:www.match-d.com.au
1360:Pleiotropy (drugs)
1350:Pharmacotoxicology
1222:was linked to the
1195:Tardive dyskinesia
1041:dietary supplement
1028:spinal anaesthesia
729:sometimes lead to
718:drug manufacturers
584:minimally invasive
510:minimally invasive
473:Medical procedures
348:herbal supplements
320:Yellow Card Scheme
307:systematic reviews
167:therapeutic effect
4148:
4147:
4105:Risk compensation
3940:
3939:
3689:Electrical injury
3531:Altitude sickness
3379:
3378:
3232:
3231:
3198:Iatrogenic anemia
3145:Physician gag law
2973:Medication Errors
2951:
2950:
2756:on March 23, 2013
2572:(12): 1192–1197.
2243:Drugs & Aging
2093:on April 11, 2013
1857:on March 30, 2013
1815:10.1111/imj.13215
1809:(10): 1189–1197.
1737:10.1111/bcp.12944
1325:Medical algorithm
1008:may be caused by
562:eczema vaccinatum
521:radiation therapy
512:surgery, such as
424:pharmacovigilance
285:Reporting systems
243:drug interactions
194:may increase the
143:
142:
121:Medical condition
119:
118:
111:
93:
4188:
4130:Streisand effect
4040:Hawthorne effect
4000:Butterfly effect
3995:Braess's paradox
3967:
3960:
3953:
3944:
3943:
3928:
3916:
3915:
3904:
3903:
3892:
3891:
3880:
3879:
3716:physical factors
3712:skin conditions
3644:Hypersensitivity
3361:Cold intolerance
3278:
3277:
3265:Consequences of
3259:
3252:
3245:
3236:
3235:
3176:Related concerns
3029:
3022:
3015:
3006:
3005:
2890:
2889:
2878:
2877:
2875:
2874:
2855:
2849:
2848:
2846:
2844:
2835:. Archived from
2829:
2823:
2822:
2820:
2818:
2798:
2792:
2791:
2789:
2787:
2772:
2766:
2765:
2763:
2761:
2752:. Archived from
2742:
2736:
2735:
2733:
2731:
2716:"Antihistamines"
2711:
2705:
2704:
2676:
2670:
2669:
2667:
2665:
2645:
2639:
2638:
2620:
2596:
2590:
2589:
2561:
2555:
2554:
2552:
2550:
2531:
2525:
2524:
2522:
2520:
2500:
2494:
2493:
2457:
2451:
2450:
2448:
2446:
2441:on April 5, 2013
2437:. Archived from
2431:
2425:
2424:
2414:
2390:
2384:
2383:
2381:
2379:
2359:
2353:
2352:
2350:
2348:
2333:
2327:
2326:
2324:
2322:
2307:
2301:
2300:
2298:
2296:
2281:
2275:
2274:
2238:
2232:
2231:
2229:
2227:
2212:
2206:
2205:
2169:
2163:
2162:
2160:
2158:
2149:. May 15, 2011.
2139:
2133:
2132:
2130:
2128:
2109:
2103:
2102:
2100:
2098:
2089:. Archived from
2079:
2073:
2072:
2035:
2029:
2028:
1992:
1986:
1985:
1983:
1982:
1973:. Archived from
1963:
1957:
1956:
1954:
1952:
1933:
1927:
1926:
1924:
1922:
1903:
1897:
1896:
1894:
1892:
1873:
1867:
1866:
1864:
1862:
1853:. Archived from
1843:
1837:
1836:
1826:
1794:
1788:
1787:
1785:
1784:
1765:
1759:
1758:
1748:
1716:
1710:
1709:
1669:
1663:
1662:
1626:
1620:
1619:
1583:
1577:
1576:
1574:
1567:
1558:
1552:
1551:
1549:
1547:
1527:
1521:
1520:
1518:
1505:
1496:
1495:
1485:
1468:(9963): 117–71.
1453:
1447:
1446:
1444:
1443:
1387:
1300:Drug interaction
1170:associated with
1129:associated with
991:associated with
982:associated with
908:associated with
896:COX-2 inhibitors
884:associated with
871:associated with
839:associated with
699:chemotherapeutic
653:drug interaction
646:pharmacokinetics
426:activities. The
344:over the counter
221:, alteration in
124:
123:
114:
107:
103:
100:
94:
92:
58:"Adverse effect"
51:
27:
19:
4196:
4195:
4191:
4190:
4189:
4187:
4186:
4185:
4151:
4150:
4149:
4144:
4090:Parkinson's law
3985:Abilene paradox
3976:
3971:
3941:
3936:
3868:
3758:Electrical burn
3715:
3714:resulting from
3713:
3711:
3705:
3677:
3664:Arthus reaction
3632:
3613:Motion sickness
3601:
3575:
3559:
3475:
3471:Oxygen toxicity
3450:
3375:
3302:
3269:
3267:external causes
3263:
3233:
3228:
3207:
3171:
3123:Political abuse
3118:
3104:Balance billing
3087:
3036:
3033:
2952:
2947:
2946:
2901:
2887:
2882:
2881:
2872:
2870:
2857:
2856:
2852:
2842:
2840:
2831:
2830:
2826:
2816:
2814:
2799:
2795:
2785:
2783:
2774:
2773:
2769:
2759:
2757:
2744:
2743:
2739:
2729:
2727:
2712:
2708:
2677:
2673:
2663:
2661:
2646:
2642:
2597:
2593:
2562:
2558:
2548:
2546:
2533:
2532:
2528:
2518:
2516:
2501:
2497:
2458:
2454:
2444:
2442:
2433:
2432:
2428:
2391:
2387:
2377:
2375:
2360:
2356:
2346:
2344:
2335:
2334:
2330:
2320:
2318:
2309:
2308:
2304:
2294:
2292:
2283:
2282:
2278:
2239:
2235:
2225:
2223:
2214:
2213:
2209:
2170:
2166:
2156:
2154:
2141:
2140:
2136:
2126:
2124:
2111:
2110:
2106:
2096:
2094:
2081:
2080:
2076:
2036:
2032:
1993:
1989:
1980:
1978:
1967:"Kidney Damage"
1965:
1964:
1960:
1950:
1948:
1935:
1934:
1930:
1920:
1918:
1905:
1904:
1900:
1890:
1888:
1875:
1874:
1870:
1860:
1858:
1845:
1844:
1840:
1795:
1791:
1782:
1780:
1767:
1766:
1762:
1717:
1713:
1670:
1666:
1627:
1623:
1584:
1580:
1572:
1565:
1559:
1555:
1545:
1543:
1528:
1524:
1516:
1506:
1499:
1454:
1450:
1441:
1439:
1388:
1384:
1379:
1374:
1273:
1246:breast implants
1212:
1152:or increase in
1145:benzodiazepines
1087:corticosteroids
1065:Lactic acidosis
1055:methylphenidate
975:antidepressants
822:
737:(the so-called
681:cytochrome P450
626:self-medication
618:
612:
590:. For example,
475:
470:
450:
437:
420:
396:
372:
316:
295:medical devices
291:clinical trials
287:
275:hospitalization
259:clinical trials
251:
192:contraindicated
122:
115:
104:
98:
95:
52:
50:
40:
28:
17:
12:
11:
5:
4194:
4184:
4183:
4178:
4173:
4171:Patient safety
4168:
4163:
4146:
4145:
4143:
4142:
4137:
4132:
4127:
4122:
4117:
4112:
4107:
4102:
4097:
4092:
4087:
4082:
4077:
4075:Osborne effect
4072:
4067:
4062:
4060:Jevons paradox
4057:
4052:
4047:
4042:
4037:
4035:Goodhart's law
4032:
4027:
4022:
4017:
4012:
4007:
4005:Campbell's law
4002:
3997:
3992:
3990:Adverse effect
3987:
3981:
3978:
3977:
3970:
3969:
3962:
3955:
3947:
3938:
3937:
3935:
3934:
3922:
3910:
3898:
3886:
3873:
3870:
3869:
3867:
3866:
3865:
3864:
3859:
3854:
3849:
3844:
3834:
3829:
3828:
3827:
3822:
3817:
3815:Wrestler's ear
3812:
3807:
3802:
3797:
3795:Surfer's knots
3792:
3787:
3782:
3777:
3772:
3762:
3761:
3760:
3750:
3745:
3740:
3735:
3730:
3725:
3719:
3717:
3707:
3706:
3704:
3703:
3698:
3697:
3696:
3685:
3683:
3679:
3678:
3676:
3675:
3669:
3668:
3667:
3666:
3661:
3656:
3651:
3640:
3638:
3637:Adverse effect
3634:
3633:
3631:
3630:
3625:
3620:
3615:
3609:
3607:
3603:
3602:
3600:
3599:
3594:
3589:
3587:Physical abuse
3583:
3581:
3577:
3576:
3574:
3573:
3567:
3565:
3561:
3560:
3558:
3557:
3556:
3555:
3549:
3543:
3538:
3533:
3523:
3522:
3521:
3511:
3510:
3509:
3504:
3499:
3494:
3483:
3481:
3477:
3476:
3474:
3473:
3468:
3458:
3456:
3452:
3451:
3449:
3448:
3443:
3438:
3433:
3428:
3423:
3418:
3413:
3408:
3406:Radiation burn
3403:
3401:Radiation acne
3398:
3393:
3387:
3385:
3381:
3380:
3377:
3376:
3374:
3373:
3368:
3363:
3358:
3353:
3348:
3343:
3338:
3337:
3336:
3331:
3326:
3316:
3310:
3308:
3304:
3303:
3301:
3300:
3295:
3290:
3284:
3282:
3275:
3271:
3270:
3262:
3261:
3254:
3247:
3239:
3230:
3229:
3227:
3226:
3219:Drug pollution
3215:
3213:
3209:
3208:
3206:
3205:
3200:
3195:
3190:
3185:
3179:
3177:
3173:
3172:
3170:
3169:
3164:
3159:
3154:
3147:
3142:
3137:
3132:
3126:
3124:
3120:
3119:
3117:
3116:
3111:
3106:
3101:
3095:
3093:
3089:
3088:
3086:
3085:
3080:
3075:
3073:Adverse effect
3070:
3065:
3063:Patient safety
3060:
3055:
3050:
3044:
3042:
3038:
3037:
3032:
3031:
3024:
3017:
3009:
3003:
3002:
2992:
2986:
2980:
2970:
2965:
2959:
2949:
2948:
2945:
2944:
2933:
2918:
2902:
2897:
2896:
2894:
2893:Classification
2886:
2885:External links
2883:
2880:
2879:
2850:
2824:
2793:
2767:
2737:
2706:
2671:
2640:
2611:(7): 798–800.
2591:
2556:
2526:
2495:
2452:
2426:
2412:10.1086/313594
2405:(1): 198–200.
2385:
2354:
2328:
2302:
2276:
2233:
2207:
2164:
2134:
2104:
2074:
2030:
1987:
1958:
1928:
1898:
1868:
1838:
1789:
1760:
1711:
1664:
1621:
1578:
1553:
1522:
1497:
1448:
1381:
1380:
1378:
1375:
1373:
1372:
1367:
1362:
1357:
1352:
1347:
1342:
1340:Patient safety
1337:
1332:
1327:
1322:
1317:
1312:
1307:
1305:EudraVigilance
1302:
1297:
1292:
1285:
1280:
1274:
1272:
1269:
1211:
1208:
1207:
1206:
1199:metoclopramide
1192:
1178:
1161:
1147:
1138:
1127:Rhabdomyolysis
1124:
1115:
1111:, such as the
1098:
1089:
1080:
1079:(for diabetes)
1062:
1048:
1030:
1021:
999:
993:corticosteroid
986:
977:
968:
958:
944:
938:hepatic injury
931:
917:
906:kidney failure
899:
892:Cardiovascular
889:
875:
866:
844:
821:
818:
665:St John's wort
614:Main article:
611:
608:
474:
471:
469:
466:
449:
446:
436:
433:
419:
416:
395:
392:
371:
368:
324:United Kingdom
315:
314:United Kingdom
312:
286:
283:
273:, or requires
250:
249:Classification
247:
208:non-compliance
147:adverse effect
141:
140:
135:
129:
128:
127:Adverse effect
120:
117:
116:
31:
29:
22:
15:
9:
6:
4:
3:
2:
4193:
4182:
4179:
4177:
4174:
4172:
4169:
4167:
4164:
4162:
4159:
4158:
4156:
4141:
4138:
4136:
4133:
4131:
4128:
4126:
4123:
4121:
4118:
4116:
4113:
4111:
4108:
4106:
4103:
4101:
4098:
4096:
4093:
4091:
4088:
4086:
4083:
4081:
4078:
4076:
4073:
4071:
4068:
4066:
4063:
4061:
4058:
4056:
4053:
4051:
4048:
4046:
4043:
4041:
4038:
4036:
4033:
4031:
4028:
4026:
4023:
4021:
4018:
4016:
4013:
4011:
4008:
4006:
4003:
4001:
3998:
3996:
3993:
3991:
3988:
3986:
3983:
3982:
3979:
3975:
3968:
3963:
3961:
3956:
3954:
3949:
3948:
3945:
3933:
3932:
3927:
3923:
3921:
3920:
3911:
3909:
3908:
3899:
3897:
3896:
3887:
3885:
3884:
3875:
3874:
3871:
3863:
3860:
3858:
3855:
3853:
3850:
3848:
3845:
3843:
3842:Skin pop scar
3840:
3839:
3838:
3835:
3833:
3830:
3826:
3823:
3821:
3818:
3816:
3813:
3811:
3808:
3806:
3803:
3801:
3798:
3796:
3793:
3791:
3790:Runner's rump
3788:
3786:
3783:
3781:
3778:
3776:
3773:
3771:
3768:
3767:
3766:
3763:
3759:
3756:
3755:
3754:
3751:
3749:
3746:
3744:
3741:
3739:
3736:
3734:
3731:
3729:
3726:
3724:
3721:
3720:
3718:
3708:
3702:
3699:
3695:
3692:
3691:
3690:
3687:
3686:
3684:
3680:
3674:
3671:
3670:
3665:
3662:
3660:
3657:
3655:
3652:
3650:
3647:
3646:
3645:
3642:
3641:
3639:
3635:
3629:
3626:
3624:
3621:
3619:
3616:
3614:
3611:
3610:
3608:
3604:
3598:
3595:
3593:
3590:
3588:
3585:
3584:
3582:
3578:
3572:
3569:
3568:
3566:
3562:
3553:
3550:
3547:
3544:
3542:
3539:
3537:
3534:
3532:
3529:
3528:
3527:
3526:High altitude
3524:
3520:
3517:
3516:
3515:
3512:
3508:
3505:
3503:
3500:
3498:
3497:Aerosinusitis
3495:
3493:
3490:
3489:
3488:
3485:
3484:
3482:
3478:
3472:
3469:
3467:
3463:
3460:
3459:
3457:
3453:
3447:
3444:
3442:
3439:
3437:
3434:
3432:
3429:
3427:
3424:
3422:
3419:
3417:
3414:
3412:
3409:
3407:
3404:
3402:
3399:
3397:
3394:
3392:
3389:
3388:
3386:
3382:
3372:
3369:
3367:
3364:
3362:
3359:
3357:
3354:
3352:
3349:
3347:
3344:
3342:
3339:
3335:
3332:
3330:
3327:
3325:
3322:
3321:
3320:
3317:
3315:
3312:
3311:
3309:
3305:
3299:
3296:
3294:
3291:
3289:
3286:
3285:
3283:
3279:
3276:
3272:
3268:
3260:
3255:
3253:
3248:
3246:
3241:
3240:
3237:
3224:
3220:
3217:
3216:
3214:
3210:
3204:
3201:
3199:
3196:
3194:
3191:
3189:
3186:
3184:
3181:
3180:
3178:
3174:
3168:
3165:
3163:
3160:
3158:
3155:
3153:
3152:
3148:
3146:
3143:
3141:
3138:
3136:
3133:
3131:
3128:
3127:
3125:
3121:
3115:
3112:
3110:
3107:
3105:
3102:
3100:
3097:
3096:
3094:
3090:
3084:
3081:
3079:
3078:Patient abuse
3076:
3074:
3071:
3069:
3066:
3064:
3061:
3059:
3058:Medical error
3056:
3054:
3051:
3049:
3046:
3045:
3043:
3039:
3030:
3025:
3023:
3018:
3016:
3011:
3010:
3007:
3000:
2996:
2993:
2990:
2987:
2984:
2981:
2978:
2974:
2971:
2969:
2966:
2963:
2960:
2957:
2954:
2953:
2943:
2939:
2938:
2934:
2932:
2928:
2927:
2923:
2919:
2917:
2913:
2912:
2908:
2904:
2903:
2900:
2895:
2891:
2868:
2864:
2860:
2854:
2839:on 2013-03-03
2838:
2834:
2828:
2812:
2808:
2804:
2797:
2781:
2777:
2771:
2755:
2751:
2747:
2741:
2725:
2721:
2717:
2710:
2702:
2698:
2694:
2690:
2687:(6): 538–44.
2686:
2682:
2675:
2659:
2655:
2651:
2644:
2636:
2632:
2628:
2624:
2619:
2614:
2610:
2606:
2602:
2595:
2587:
2583:
2579:
2575:
2571:
2567:
2560:
2544:
2540:
2536:
2530:
2514:
2510:
2506:
2499:
2491:
2487:
2483:
2479:
2475:
2471:
2468:(2): 111–22.
2467:
2463:
2456:
2440:
2436:
2430:
2422:
2418:
2413:
2408:
2404:
2400:
2396:
2389:
2373:
2369:
2365:
2358:
2342:
2338:
2332:
2316:
2312:
2306:
2290:
2286:
2280:
2272:
2268:
2264:
2260:
2256:
2252:
2249:(6): 439–50.
2248:
2244:
2237:
2221:
2217:
2211:
2203:
2199:
2195:
2191:
2187:
2183:
2180:(3): 419–27.
2179:
2175:
2168:
2152:
2148:
2144:
2138:
2122:
2118:
2114:
2108:
2092:
2088:
2084:
2078:
2070:
2066:
2062:
2058:
2054:
2050:
2046:
2042:
2034:
2026:
2022:
2018:
2014:
2010:
2006:
2002:
1998:
1991:
1977:on 2013-05-04
1976:
1972:
1968:
1962:
1946:
1942:
1938:
1932:
1916:
1912:
1908:
1902:
1886:
1882:
1878:
1872:
1856:
1852:
1848:
1842:
1834:
1830:
1825:
1820:
1816:
1812:
1808:
1804:
1800:
1793:
1778:
1774:
1770:
1764:
1756:
1752:
1747:
1742:
1738:
1734:
1730:
1726:
1722:
1715:
1707:
1703:
1699:
1695:
1691:
1687:
1684:(10): 781–8.
1683:
1679:
1675:
1668:
1660:
1656:
1652:
1648:
1644:
1640:
1636:
1632:
1625:
1617:
1613:
1609:
1605:
1601:
1597:
1594:(4): 437–43.
1593:
1589:
1582:
1571:
1564:
1557:
1541:
1537:
1533:
1526:
1515:
1511:
1504:
1502:
1493:
1489:
1484:
1479:
1475:
1471:
1467:
1463:
1459:
1452:
1437:
1433:
1429:
1425:
1421:
1417:
1413:
1409:
1405:
1401:
1397:
1393:
1386:
1382:
1371:
1368:
1366:
1363:
1361:
1358:
1356:
1353:
1351:
1348:
1346:
1343:
1341:
1338:
1336:
1333:
1331:
1328:
1326:
1323:
1321:
1318:
1316:
1313:
1311:
1308:
1306:
1303:
1301:
1298:
1296:
1293:
1291:
1290:
1286:
1284:
1281:
1279:
1276:
1275:
1268:
1266:
1265:breast cancer
1262:
1258:
1253:
1251:
1250:immune system
1247:
1244:
1239:
1237:
1233:
1229:
1225:
1221:
1217:
1210:Controversies
1204:
1203:antipsychotic
1200:
1196:
1193:
1190:
1186:
1182:
1179:
1177:
1176:nitroglycerin
1173:
1169:
1165:
1162:
1159:
1158:antihistamine
1155:
1151:
1148:
1146:
1142:
1139:
1136:
1132:
1128:
1125:
1123:
1119:
1116:
1114:
1110:
1106:
1102:
1099:
1097:
1093:
1090:
1088:
1084:
1081:
1078:
1074:
1070:
1066:
1063:
1060:
1056:
1052:
1049:
1046:
1042:
1038:
1034:
1031:
1029:
1025:
1022:
1019:
1015:
1011:
1007:
1003:
1000:
998:
994:
990:
987:
985:
981:
978:
976:
972:
969:
966:
962:
959:
956:
952:
948:
945:
943:
939:
935:
932:
929:
925:
921:
918:
915:
911:
907:
903:
900:
897:
893:
890:
887:
883:
879:
876:
874:
870:
869:Birth defects
867:
864:
860:
856:
852:
848:
845:
842:
838:
835:
831:
827:
824:
823:
817:
815:
810:
808:
804:
800:
796:
792:
788:
784:
778:
776:
772:
768:
767:heart disease
764:
760:
756:
755:teratogenesis
752:
748:
744:
740:
736:
732:
731:public health
727:
723:
719:
714:
712:
708:
704:
700:
697:
693:
689:
685:
682:
678:
674:
673:phytotherapic
670:
666:
662:
658:
654:
649:
647:
643:
639:
635:
631:
627:
623:
617:
607:
605:
601:
597:
596:radiocontrast
594:reactions to
593:
589:
585:
581:
577:
573:
571:
567:
563:
559:
555:
551:
547:
544:
540:
536:
534:
530:
526:
522:
517:
515:
511:
507:
503:
499:
495:
491:
487:
483:
479:
465:
463:
459:
454:
445:
441:
432:
429:
425:
415:
413:
409:
405:
401:
391:
389:
385:
381:
377:
376:United States
370:United States
367:
365:
362:, as well as
361:
357:
353:
349:
345:
341:
337:
333:
329:
325:
321:
311:
308:
304:
300:
296:
292:
282:
278:
276:
272:
271:birth defects
268:
264:
263:adverse event
260:
255:
246:
244:
240:
236:
232:
228:
224:
220:
216:
211:
209:
205:
201:
197:
193:
189:
185:
181:
180:medical error
177:
172:
168:
164:
160:
156:
152:
148:
139:
136:
134:
130:
125:
113:
110:
102:
99:February 2011
91:
88:
84:
81:
77:
74:
70:
67:
63:
60: –
59:
55:
54:Find sources:
48:
44:
38:
37:
32:This article
30:
26:
21:
20:
4065:Murphy's law
4050:Hydra effect
4045:Hutber's law
4010:Cobra effect
3989:
3929:
3917:
3905:
3893:
3881:
3836:
3764:
3752:
3592:Sexual abuse
3580:Maltreatment
3507:Pneumothorax
3366:Acrocyanosis
3356:Aerosol burn
3298:Heat syncope
3293:Hyperthermia
3203:Hand washing
3149:
3130:Drapetomania
3099:Medical debt
3072:
3048:Iatrogenesis
3035:Medical harm
2935:
2920:
2905:
2871:. Retrieved
2862:
2853:
2841:. Retrieved
2837:the original
2827:
2815:. Retrieved
2806:
2796:
2784:. Retrieved
2770:
2758:. Retrieved
2754:the original
2749:
2740:
2728:. Retrieved
2720:Patient.info
2719:
2709:
2684:
2680:
2674:
2662:. Retrieved
2653:
2643:
2608:
2604:
2594:
2569:
2565:
2559:
2547:. Retrieved
2538:
2529:
2517:. Retrieved
2509:Patient.info
2508:
2498:
2465:
2461:
2455:
2443:. Retrieved
2439:the original
2429:
2402:
2398:
2388:
2376:. Retrieved
2367:
2357:
2345:. Retrieved
2331:
2319:. Retrieved
2305:
2293:. Retrieved
2279:
2246:
2242:
2236:
2224:. Retrieved
2210:
2177:
2173:
2167:
2155:. Retrieved
2146:
2137:
2125:. Retrieved
2116:
2107:
2095:. Retrieved
2091:the original
2086:
2077:
2047:(4): 531–6.
2044:
2040:
2033:
2003:(6): 491–9.
2000:
1996:
1990:
1979:. Retrieved
1975:the original
1970:
1961:
1949:. Retrieved
1940:
1931:
1919:. Retrieved
1910:
1901:
1889:. Retrieved
1880:
1871:
1859:. Retrieved
1855:the original
1850:
1841:
1806:
1802:
1792:
1781:. Retrieved
1772:
1763:
1731:(1): 17–29.
1728:
1724:
1714:
1681:
1677:
1667:
1634:
1630:
1624:
1591:
1587:
1581:
1556:
1544:. Retrieved
1535:
1525:
1465:
1461:
1451:
1440:. Retrieved
1399:
1395:
1385:
1365:Polypharmacy
1287:
1254:
1240:
1213:
1168:heart attack
1094:damage from
1075:therapy) or
1071:(Zerit, for
1033:Hypertension
1010:chemotherapy
922:, following
898:(i.e. Vioxx)
811:
779:
747:cerivastatin
735:fenfluramine
715:
668:
650:
622:pharmacology
619:
574:
537:
523:, may cause
518:
490:inflammation
476:
468:By situation
455:
451:
442:
438:
421:
397:
373:
340:prescription
317:
288:
279:
256:
252:
231:pathological
225:, levels of
212:
171:complication
155:intervention
146:
144:
138:Pharmacology
105:
96:
86:
79:
72:
65:
53:
41:Please help
36:verification
33:
4181:Drug safety
4125:Social trap
4120:Serendipity
4020:Externality
3649:Anaphylaxis
3623:Airsickness
3618:Seasickness
3324:Trench foot
3314:Hypothermia
3274:Temperature
3083:Never event
2654:Mayo Clinic
2462:Drug Safety
1674:Gøtzsche PC
1536:www.fda.gov
1224:MMR vaccine
1205:medications
1135:cholesterol
1096:paracetamol
1057:(Ritalin),
984:vaccination
955:psychiatric
873:thalidomide
841:misoprostol
830:miscarriage
743:thalidomide
610:Medications
600:colonoscopy
588:noninvasive
539:Vaccination
448:Limitations
418:New Zealand
356:pharmacists
223:body weight
169:. The term
163:side effect
4155:Categories
4015:CSI effect
3847:Skin track
3800:Tennis toe
3728:Pinch mark
3710:Ungrouped
3654:Angioedema
3571:Starvation
3541:Death zone
3487:Barotrauma
3346:Chilblains
2975:—from the
2942:D000069451
2873:2023-05-20
2368:Livestrong
1981:2013-04-28
1911:WebMD News
1783:2019-06-01
1442:2021-06-01
1396:The Lancet
1377:References
1370:Toxicology
1228:thiomersal
1187:and other
1185:fluoxetine
1172:sildenafil
1150:Drowsiness
1122:sildenafil
1105:thrombosis
1085:caused by
1043:status of
1026:following
949:caused by
942:interferon
940:caused by
934:Depression
930:(Diprivan)
914:antibiotic
910:gentamicin
857:, such as
855:analgesics
837:hemorrhage
807:dermatitis
775:withdrawal
771:neuropathy
741:episode),
688:metabolism
677:depression
604:intestinal
576:Diagnostic
570:dermatitis
568:or atopic
543:attenuated
502:amputation
498:blood flow
486:hemorrhage
352:physicians
184:iatrogenic
157:, such as
151:medication
69:newspapers
3852:Slap mark
3820:Coral cut
3384:Radiation
3351:Frostbite
2863:Frontline
2843:March 16,
2817:March 16,
2786:March 16,
2760:March 20,
2730:March 20,
2664:March 20,
2549:March 20,
2519:March 20,
2445:March 20,
2378:March 20,
2321:March 20,
2295:March 20,
2226:March 20,
2157:March 20,
2127:March 20,
2117:eHealthMe
2097:March 20,
1951:March 20,
1921:March 20,
1891:March 20,
1881:rehabinfo
1861:March 20,
1416:0140-6736
1283:Biosafety
1201:and many
1077:metformin
1069:stavudine
1037:ephedrine
1002:Hair loss
997:eye drops
967:(Xenical)
882:intestine
851:sedatives
847:Addiction
787:dizziness
751:rofecoxib
722:marketing
657:morbidity
546:pathogens
482:infection
458:influenza
400:Australia
394:Australia
336:medicines
219:mortality
215:morbidity
204:prognosis
188:physician
153:or other
133:Specialty
3907:Glossary
3883:Category
3701:Drowning
3480:Pressure
3466:Asphyxia
3281:Elevated
3041:Concepts
2867:Archived
2811:Archived
2807:CBS News
2780:Archived
2724:Archived
2658:Archived
2627:17952749
2586:21176332
2543:Archived
2539:wiseGEEK
2513:Archived
2490:25933949
2482:10672894
2421:10619755
2372:Archived
2341:Archived
2315:Archived
2289:Archived
2271:22380777
2263:10641955
2220:Archived
2202:20270210
2194:16026253
2151:Archived
2121:Archived
2069:33773564
2061:18079286
2025:39426004
1945:Archived
1915:Archived
1885:Archived
1833:27527376
1777:Archived
1755:27016266
1706:17032571
1698:15545678
1659:22188119
1651:15968034
1616:14529735
1608:11242428
1570:Archived
1546:15 March
1540:Archived
1514:Archived
1492:25530442
1436:Archived
1432:17662080
1424:11072960
1271:See also
1243:silicone
1236:vaccines
1216:lawsuits
1154:appetite
1141:Seizures
1118:Priapism
1059:Adderall
1051:Insomnia
1047:extracts
1024:Headache
1018:leukemia
1012:against
989:Glaucoma
965:orlistat
961:Diarrhea
947:Diabetes
928:propofol
924:sedation
902:Deafness
878:Bleeding
863:morphine
859:diazepam
849:to many
826:Abortion
803:headache
799:vomiting
791:diarrhea
739:fen-phen
726:toxicity
628:. Thus,
592:allergic
580:invasive
506:gangrene
494:scarring
384:MedWatch
364:patients
330:and the
235:symptoms
3919:Outline
3895:Commons
3659:Allergy
3462:Hypoxia
3446:Sunburn
3307:Reduced
2701:3427560
2635:6629753
2347:May 20,
2087:Medsafe
2017:9836214
1824:5129475
1746:4917803
1483:4340604
1355:Placebo
1232:mercury
1226:(or to
1181:Suicide
1156:due to
1131:statins
1101:Melasma
1045:ephedra
995:-based
888:therapy
886:aspirin
880:of the
834:uterine
814:MATCH-D
795:malaise
701:drugs,
684:enzymes
558:malaise
533:tissues
478:Surgery
374:In the
227:enzymes
200:disease
159:surgery
83:scholar
4070:Nocebo
3931:Portal
3837:iv use
3606:Travel
3554:(HACE)
3548:(HAPE)
3455:Oxygen
2931:995.89
2699:
2633:
2625:
2584:
2488:
2480:
2419:
2269:
2261:
2200:
2192:
2067:
2059:
2023:
2015:
1831:
1821:
1753:
1743:
1704:
1696:
1657:
1649:
1614:
1606:
1490:
1480:
1462:Lancet
1430:
1422:
1414:
1335:Nocebo
1220:autism
1164:Stroke
1137:drugs)
1061:, etc.
1020:, etc.
1014:cancer
1006:anemia
957:drugs)
865:, etc.
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