391:
368:
36:
2466:
290:
265:
2481:
656:
649:
642:
397:
296:
110:
136:
404:
303:
2465:
2386:
Mori T, Kawara S, Shinozaki M, et al. (1999). "Role and interaction of connective tissue growth factor with transforming growth factor-beta in persistent fibrosis: A mouse fibrosis model".
2349:
Fromigué O, Marie PJ, Lomri A (1998). "Bone morphogenetic protein-2 and transforming growth factor-beta2 interact to modulate human bone marrow stromal cell proliferation and differentiation".
2040:
Webb NR, Madisen L, Rose TM, Purchio AF (1989). "Structural and sequence analysis of TGF-beta 2 cDNA clones predicts two different precursor proteins produced by alternative mRNA splicing".
2234:"The soluble exoplasmic domain of the type II transforming growth factor (TGF)-beta receptor. A heterogeneously glycosylated protein with high affinity and selectivity for TGF-beta ligands"
2098:
Barton DE, Foellmer BE, Du J, et al. (1989). "Chromosomal mapping of genes for transforming growth factors beta 2 and beta 3 in man and mouse: dispersion of TGF-beta gene family".
3583:
2011:
Bodmer S, Podlisny MB, Selkoe DJ, et al. (1990). "Transforming growth factor-beta bound to soluble derivatives of the beta amyloid precursor protein of
Alzheimer's disease".
2480:
3576:
1937:
Schlunegger MP, Grütter MG (1992). "An unusual feature revealed by the crystal structure at 2.2 A resolution of human transforming growth factor-beta 2".
1414:
1395:
226:
2199:"Binding of transforming growth factor-beta (TGF-beta) to pregnancy zone protein (PZP). Comparison to the TGF-beta-alpha 2-macroglobulin interaction"
3569:
5151:
1982:
Noma T, Glick AB, Geiser AG, et al. (1992). "Molecular cloning and structure of the human transforming growth factor-beta 2 gene promoter".
4345:
3956:
3859:
65:
2121:"Complementary DNA for human glioblastoma-derived T cell suppressor factor, a novel member of the transforming growth factor-beta gene family"
5258:
4976:
3739:
5240:
4933:
4776:
4615:
4330:
3060:
2521:
4534:
4435:
4223:
4218:
4188:
4183:
4083:
2821:
2542:
4203:
3666:
2399:
2362:
1630:
2308:"Betaglycan can act as a dual modulator of TGF-beta access to signaling receptors: mapping of ligand binding and GAG attachment sites"
1637:
4425:
4350:
4173:
4073:
3961:
3864:
3714:
2968:
2958:
2952:
2947:
2937:
2932:
2927:
2922:
2917:
4228:
4178:
3869:
3719:
3093:
4529:
4340:
3951:
3854:
3849:
5141:
3447:
3442:
3318:
2445:
2269:"Interaction of the small interstitial proteoglycans biglycan, decorin and fibromodulin with transforming growth factor beta"
5223:
2474:: AN UNUSUAL FEATURE REVEALED BY THE CRYSTAL STRUCTURE AT 2.2 ANGSTROMS RESOLUTION OF HUMAN TRANSFORMING GROWTH FACTOR-BETA2
5281:
3519:
3514:
3509:
2774:
1822:
133:
2069:
Madisen L, Webb NR, Rose TM, et al. (1988). "Transforming growth factor-beta 2: cDNA cloning and sequence analysis".
5202:
2624:
3501:
2866:
3121:
87:
390:
58:
5018:
2514:
4449:
1779:
Wick W, Platten M, Weller M (2002). "Glioma cell invasion: regulation of metalloproteinase activity by TGF-beta".
5227:
5206:
5060:
4486:
4130:
3826:
3681:
3606:
3407:
3336:
3006:
2729:
2564:
367:
3468:
3136:
1459:
4892:
4728:
4593:
4476:
4378:
4304:
4116:
4007:
3671:
3016:
2689:
2682:
2677:
2672:
2667:
1440:
4928:
4864:
4684:
4561:
4260:
3906:
3395:
3390:
3086:
2662:
2657:
2652:
2647:
2642:
2637:
289:
264:
206:
3592:
3524:
3286:
2507:
403:
302:
4860:
4680:
4557:
4256:
3902:
3795:
3656:
3380:
3363:
3328:
3165:
2632:
396:
295:
2438:
1270:
positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation
1265:
negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation
193:
48:
5004:
3897:
3785:
2751:
2534:
3550:
3110:
2849:
2794:
2778:
1609:
1584:
1558:
1533:
214:
52:
44:
3529:
3313:
3079:
5291:
1613:
1588:
1554:
1529:
69:
1735:
1898:"Crystal structure of transforming growth factor-beta 2: an unusual fold for the superfamily"
1697:
17:
2489:: CRYSTAL STRUCTURE OF TRANSFORMING GROWTH FACTOR-BETA2: AN UNUSUAL FOLD FOR THE SUPERFAMILY
2431:
1946:
1909:
1726:
278:
234:
1705:-derived T-cell suppressor factor, G-TSF, BSC-1 cell growth inhibitor, Polyergin, Cetermin
8:
3545:
2901:
2586:
2499:
1950:
1913:
5101:
3598:
3561:
2976:
2765:
2411:
2374:
2332:
2307:
2289:
2268:
2215:
2198:
2136:
1970:
1804:
238:
2180:
2163:
2145:
2120:
1879:
1854:
1763:
1329:
1324:
1319:
1314:
1309:
1304:
1299:
1294:
1289:
1284:
1279:
1274:
1269:
1264:
1259:
1254:
1249:
1244:
1239:
1234:
1229:
1224:
1219:
1214:
1209:
1204:
1199:
1194:
1189:
1184:
1179:
1174:
1169:
1164:
1159:
1154:
1149:
1144:
1139:
1134:
1129:
1124:
1119:
1114:
1109:
1104:
1099:
1094:
1089:
1084:
1079:
1074:
1069:
1064:
1059:
1054:
1049:
1044:
1039:
1034:
1029:
1024:
1019:
1014:
1009:
1004:
999:
994:
989:
984:
979:
974:
969:
964:
959:
954:
949:
944:
939:
934:
929:
924:
919:
914:
909:
904:
899:
894:
889:
884:
879:
874:
869:
864:
859:
854:
849:
844:
839:
834:
829:
824:
819:
814:
809:
804:
788:
783:
778:
773:
768:
763:
758:
742:
737:
732:
727:
722:
717:
712:
707:
702:
697:
5286:
5126:
2996:
2556:
2403:
2366:
2337:
2294:
2255:
2220:
2185:
2150:
2107:
2086:
2057:
2028:
2024:
1999:
1962:
1925:
1884:
1841:
1796:
1767:
186:
126:
2415:
2378:
1808:
5146:
5136:
3021:
3011:
2770:
2552:
2395:
2358:
2327:
2319:
2284:
2276:
2245:
2210:
2175:
2140:
2132:
2078:
2049:
2020:
1991:
1974:
1954:
1917:
1874:
1866:
1831:
1788:
1759:
483:
414:
358:
313:
218:
4957:
4887:
4882:
4800:
4723:
4718:
4588:
4583:
4406:
4299:
4294:
4054:
3941:
3936:
3821:
3300:
3001:
458:
242:
5263:
National Center for
Biotechnology Information, U.S. National Library of Medicine
5245:
National Center for
Biotechnology Information, U.S. National Library of Medicine
2905:
2530:
559:
2164:"Complete amino acid sequence of human transforming growth factor type beta 2"
1995:
1792:
655:
648:
641:
5275:
5111:
3704:
3102:
2053:
1711:
1708:
684:
1921:
619:
497:
5131:
4514:
4509:
4198:
4158:
4153:
3729:
2407:
2250:
2233:
1888:
1845:
1800:
1702:
476:
255:
2400:
10.1002/(SICI)1097-4652(199910)181:1<153::AID-JCP16>3.0.CO;2-K
2370:
2363:
10.1002/(SICI)1097-4644(19980315)68:4<411::AID-JCB2>3.0.CO;2-T
2341:
2323:
2298:
2259:
2224:
2196:
2189:
2154:
2111:
2090:
2061:
2032:
2003:
1966:
1929:
1771:
1677:
1672:
5121:
4819:
4519:
4163:
3031:
2991:
2082:
1715:
1504:
1485:
109:
1836:
1817:
1750:
Clark DA, Coker R (1998). "Transforming growth factor-beta (TGF-beta)".
5161:
5072:
5064:
4854:
4674:
4498:
4490:
4193:
4142:
4134:
4001:
3838:
3830:
3779:
3693:
3685:
3645:
3351:
3341:
2887:
2579:
2569:
1250:
regulation of apoptotic process involved in outflow tract morphogenesis
375:
272:
222:
2280:
1015:
positive regulation of pathway-restricted SMAD protein phosphorylation
163:
159:
155:
5054:
5050:
5041:
4951:
4947:
4918:
4850:
4846:
4794:
4790:
4766:
4670:
4666:
4633:
4629:
4471:
4430:
4213:
4111:
4078:
4048:
4044:
4025:
3997:
3993:
3790:
3775:
3771:
3651:
3641:
3637:
3452:
3308:
2724:
1958:
1870:
1855:"Epithelial-mesenchymal transition and its implications for fibrosis"
1359:
442:
429:
341:
328:
230:
5027:
4458:
1897:
5178:
4243:
3884:
3262:
1693:
1661:
1300:
positive regulation of pri-miRNA transcription by RNA polymerase II
5028:
4545:
4459:
4098:
1696:
that performs many cellular functions and has a vital role during
5116:
5106:
5046:
4943:
4842:
4786:
4662:
4625:
4040:
3989:
3767:
3633:
3437:
3376:
3071:
2986:
2981:
2305:
1471:
1426:
1344:
1340:
210:
5167:
4965:
4961:
4829:
4808:
4804:
4644:
4414:
4410:
4208:
4062:
4058:
3044:
2943:
2913:
2859:
2854:
2831:
2826:
2816:
2809:
2804:
2119:
de Martin R, Haendler B, Hofer-Warbinek R, et al. (1988).
2118:
1722:
1719:
1645:
1381:
664:
4987:
2423:
2197:
Philip A, Bostedt L, Stigbrand T, O'Connor-McCourt MD (1994).
1055:
positive regulation of phosphatidylinositol 3-kinase signaling
5096:
4986:
4923:
4771:
4760:
4756:
4712:
4708:
4704:
4577:
4544:
4480:
4396:
4390:
4324:
4288:
4284:
4280:
4124:
4120:
4030:
4019:
3930:
3926:
3815:
3811:
3660:
3491:
3486:
3481:
3476:
3432:
3427:
3422:
3417:
3281:
3276:
3271:
3247:
3241:
3235:
3229:
3209:
3205:
3196:
3192:
3183:
3179:
3039:
2871:
2799:
2744:
2739:
2734:
2613:
2606:
2601:
2596:
4912:
4908:
4904:
4900:
4896:
4876:
4872:
4868:
4752:
4748:
4744:
4740:
4736:
4732:
4700:
4696:
4692:
4688:
4609:
4605:
4601:
4597:
4573:
4569:
4565:
4386:
4382:
4360:
4320:
4316:
4312:
4308:
4276:
4272:
4268:
4264:
4238:
4093:
4015:
4011:
3971:
3922:
3918:
3914:
3910:
3879:
3807:
3803:
3799:
3749:
3675:
3615:
3201:
3188:
3175:
3153:
3149:
3145:
3140:
3132:
2719:
2714:
2709:
2704:
2699:
2694:
2591:
2267:
Hildebrand A, Romarís M, Rasmussen LM, et al. (1994).
1730:
1725:. There are two named isoforms of this protein, created by
965:
positive regulation of epithelial to mesenchymal transition
2529:
2306:
López-Casillas F, Payne HM, Andres JL, Massagué J (1994).
2266:
885:
transforming growth factor beta receptor signaling pathway
875:
positive regulation of cell adhesion mediated by integrin
810:
regulation of transforming growth factor beta2 production
708:
type III transforming growth factor beta receptor binding
3591:
698:
type II transforming growth factor beta receptor binding
466:
4991:
3593:
4361:
4239:
4094:
3972:
3880:
3750:
3620:
3616:
2039:
1205:
negative regulation of Ras protein signal transduction
2161:
1895:
870:
negative regulation of macrophage cytokine production
631:
197:, TGF-beta2, transforming growth factor beta 2, G-TSF
2010:
1050:
positive regulation of cell population proliferation
895:
positive regulation of stress-activated MAPK cascade
890:
negative regulation of cell population proliferation
865:
negative regulation of alkaline phosphatase activity
855:
negative regulation of epithelial cell proliferation
830:
positive regulation of integrin biosynthetic process
2385:
5219:
5217:
5215:
5198:
5196:
5194:
4365:
3976:
3754:
2348:
2232:Lin HY, Moustakas A, Knaus P, et al. (1995).
1936:
1305:embryo development ending in birth or egg hatching
940:positive regulation of cardioblast differentiation
2231:
1778:
413:
312:
5273:
5026:
4830:
4645:
2097:
1714:protein. It is known to suppress the effects of
915:positive regulation of epithelial cell migration
718:transforming growth factor beta receptor binding
57:but its sources remain unclear because it lacks
5212:
5191:
4649:
2068:
1981:
1230:pathway-restricted SMAD protein phosphorylation
985:regulation of complement-dependent cytotoxicity
845:positive regulation of neuron apoptotic process
27:Protein-coding gene in the species Homo sapiens
5224:GRCm38: Ensembl release 89: ENSMUSG00000039239
1896:Daopin S, Piez KA, Ogawa Y, Davies DR (1992).
1852:
1290:positive regulation of Notch signaling pathway
1145:ventricular trabecula myocardium morphogenesis
3577:
3087:
2515:
2439:
1818:"Chronic liver injury, TGF-beta, and cancer"
1075:cardiac epithelial to mesenchymal transition
5203:GRCh38: Ensembl release 89: ENSG00000092969
1320:regulation of cell population proliferation
3584:
3570:
3094:
3080:
2522:
2508:
2446:
2432:
1815:
1749:
1690:Transforming growth factor-beta 2 (TGF-β2)
2331:
2288:
2249:
2214:
2179:
2162:Marquardt H, Lioubin MN, Ikeda T (1987).
2144:
1878:
1835:
1275:regulation of signaling receptor activity
88:Learn how and when to remove this message
1255:substantia propria of cornea development
990:positive regulation of protein secretion
975:positive regulation of timing of catagen
840:positive regulation of heart contraction
789:collagen-containing extracellular matrix
14:
5274:
1280:negative regulation of gene expression
1040:negative regulation of immune response
980:positive regulation of immune response
3565:
3075:
2503:
2427:
1823:Experimental & Molecular Medicine
1140:cardiac right ventricle morphogenesis
1065:activation of protein kinase activity
1000:embryonic digestive tract development
905:extrinsic apoptotic signaling pathway
418:
379:
374:
317:
276:
271:
1245:pharyngeal arch artery morphogenesis
1125:atrioventricular valve morphogenesis
1070:positive regulation of cell division
995:epithelial to mesenchymal transition
29:
1285:negative regulation of angiogenesis
1260:cranial skeletal system development
955:positive regulation of ossification
743:protein heterodimerization activity
24:
5094:Endogenous antagonists/inhibitors:
3101:
2216:10.1111/j.1432-1033.1994.tb18781.x
2137:10.1002/j.1460-2075.1987.tb02700.x
1742:
1155:atrial septum primum morphogenesis
1110:outflow tract septum morphogenesis
935:negative regulation of cell growth
925:positive regulation of cell growth
25:
5303:
1692:is a secreted protein known as a
1200:positive regulation of cell cycle
1135:endocardial cushion morphogenesis
960:cardiac muscle cell proliferation
728:protein homodimerization activity
2479:
2464:
1295:SMAD protein signal transduction
1235:ventricular septum morphogenesis
654:
647:
640:
402:
395:
389:
366:
301:
294:
288:
263:
108:
34:
3408:Relaxin family peptide hormones
2543:TGF beta superfamily of ligands
2453:
1325:regulation of apoptotic process
1310:regulation of timing of catagen
1115:membranous septum morphogenesis
900:cell-cell junction organization
5251:
5233:
3870:ML-347 (LDN-193719, VU0469381)
3720:ML-347 (LDN-193719, VU0469381)
2690:Growth differentiation factors
1853:Kalluri R, Neilson EG (2004).
665:More reference expression data
620:More reference expression data
13:
1:
2181:10.1016/S0021-9258(18)45325-2
2013:Biochem. Biophys. Res. Commun
1764:10.1016/S1357-2725(97)00128-3
1195:dopamine biosynthetic process
1190:ascending aorta morphogenesis
1130:pulmonary valve morphogenesis
880:cell population proliferation
387:
286:
2275:. 302. ( Pt 2) (2): 527–34.
2025:10.1016/0006-291X(90)91229-L
1315:secondary palate development
1180:embryonic limb morphogenesis
1030:salivary gland morphogenesis
910:collagen fibril organization
769:platelet alpha granule lumen
598:Epithelium of choroid plexus
7:
5282:Genes on human chromosome 1
4209:RepSox (E-616452, SJN-2511)
2633:Bone morphogenetic proteins
1240:atrial septum morphogenesis
1185:hair follicle morphogenesis
1090:skeletal system development
825:cardioblast differentiation
10:
5308:
3381:Insulin-like growth factor
1752:Int. J. Biochem. Cell Biol
1330:regulation of MAPK cascade
1210:somatic stem cell division
1150:endocardial cushion fusion
703:signaling receptor binding
5259:"Mouse PubMed Reference:"
5241:"Human PubMed Reference:"
5086:
5017:
4985:
4828:
4643:
4543:
4457:
4448:
4359:
4237:
4199:Galunisertib (LY-2157299)
4092:
3970:
3878:
3748:
3614:
3605:
3538:
3500:
3467:
3404:
3373:
3362:
3327:
3299:
3257:
3218:
3162:
3118:
3109:
3053:
3030:
2967:
2900:
2880:
2842:
2787:
2764:
2622:
2550:
2541:
2459:
1996:10.3109/08977199109043910
1676:
1671:
1667:
1660:
1644:
1638:Chr 1: 186.35 – 186.44 Mb
1631:Chr 1: 218.35 – 218.44 Mb
1625:
1606:
1602:
1581:
1577:
1570:
1551:
1547:
1526:
1522:
1515:
1502:
1498:
1483:
1479:
1470:
1457:
1453:
1438:
1434:
1425:
1412:
1408:
1393:
1389:
1380:
1365:
1358:
1354:
1338:
1160:neural retina development
1120:heart valve morphogenesis
1105:hair follicle development
683:
679:
662:
639:
630:
617:
566:
557:
504:
495:
465:
457:
453:
436:
423:
386:
365:
356:
352:
335:
322:
285:
262:
253:
249:
204:
201:
191:
184:
179:
152:
147:
130:
125:
120:
116:
107:
102:
5147:Thrombospondin 1 (THBS1)
4929:Osteogenin (BMP3, BMP3A)
2850:Activin type 2 receptors
2795:Activin type 1 receptors
2054:10.1089/dna.1.1988.7.493
815:response to progesterone
520:tendon of biceps brachii
43:This article includes a
3221:FGF homologous factors:
1922:10.1126/science.1631557
1793:10.1023/A:1012209518843
835:protein phosphorylation
594:internal carotid artery
586:external carotid artery
72:more precise citations.
4346:Dorsomorphin (BML-275)
3957:Dorsomorphin (BML-275)
3860:Dorsomorphin (BML-275)
2752:Anti-müllerian hormone
2535:TGFβ signaling pathway
2251:10.1074/jbc.270.6.2747
1170:male gonad development
1025:platelet degranulation
860:uterine wall breakdown
723:growth factor activity
2324:10.1083/jcb.124.4.557
1698:embryonic development
1220:inner ear development
1080:BMP signaling pathway
1035:generation of neurons
920:neutrophil chemotaxis
528:minor salivary glands
3596:receptor superfamily
3502:Vascular endothelial
2083:10.1089/dna.1988.7.1
1727:alternative splicing
1700:(alternative names:
945:glial cell migration
930:response to wounding
764:extracellular matrix
759:extracellular region
733:amyloid-beta binding
544:smooth muscle tissue
420:1 H5|1 89.95 cM
381:Chromosome 1 (mouse)
279:Chromosome 1 (human)
148:List of PDB id codes
121:Available structures
5164:(against myostatin)
2587:Activin and inhibin
1951:1992Natur.358..430S
1914:1992Sci...257..369D
1837:10.1038/emm.2001.31
1816:Bissell DM (2002).
1100:neural tube closure
1020:heart morphogenesis
1010:cell-cell signaling
1005:response to hypoxia
774:extracellular space
606:submandibular gland
540:islet of Langerhans
516:germinal epithelium
5170:(against endoglin)
4527:Kinase inhibitors:
4423:Kinase inhibitors:
4338:Kinase inhibitors:
4171:Kinase inhibitors:
4071:Kinase inhibitors:
3949:Kinase inhibitors:
3847:Kinase inhibitors:
3712:Kinase inhibitors:
2766:TGF beta receptors
1460:ENSMUSG00000039239
1225:uterus development
1215:neuron development
1095:kidney development
1045:cell morphogenesis
798:Biological process
784:neuronal cell body
752:Cellular component
691:Molecular function
570:epithelium of lens
45:list of references
5187:
5186:
5082:
5081:
5013:
5012:
4444:
4443:
3737:Other inhibitors:
3559:
3558:
3463:
3462:
3295:
3294:
3069:
3068:
2969:Ligand inhibitors
2896:
2895:
2760:
2759:
2497:
2496:
2281:10.1042/bj3020527
1687:
1686:
1683:
1682:
1656:
1655:
1621:
1620:
1596:
1595:
1566:
1565:
1541:
1540:
1511:
1510:
1492:
1491:
1466:
1465:
1447:
1446:
1421:
1420:
1402:
1401:
1350:
1349:
1165:heart development
713:cytokine activity
675:
674:
671:
670:
626:
625:
613:
612:
551:
550:
449:
448:
348:
347:
243:TGFB2 - orthologs
175:
174:
171:
170:
131:Ortholog search:
98:
97:
90:
16:(Redirected from
5299:
5267:
5266:
5255:
5249:
5248:
5237:
5231:
5221:
5210:
5200:
5030:
5024:
5023:
4993:
4989:
4974:Decoy receptors:
4919:Myostatin (GDF8)
4832:
4817:Decoy receptors:
4767:Myostatin (GDF8)
4651:
4647:
4547:
4461:
4455:
4454:
4367:
4363:
4245:
4241:
4100:
4096:
4026:Myostatin (GDF8)
3978:
3974:
3886:
3882:
3756:
3752:
3727:Decoy receptors:
3622:
3618:
3612:
3611:
3595:
3586:
3579:
3572:
3563:
3562:
3469:Platelet-derived
3411:
3384:
3371:
3370:
3265:
3223:
3169:
3126:
3116:
3115:
3096:
3089:
3082:
3073:
3072:
2785:
2784:
2548:
2547:
2524:
2517:
2510:
2501:
2500:
2483:
2468:
2448:
2441:
2434:
2425:
2424:
2419:
2388:J. Cell. Physiol
2382:
2351:J. Cell. Biochem
2345:
2335:
2302:
2292:
2263:
2253:
2228:
2218:
2193:
2183:
2174:(25): 12127–31.
2158:
2148:
2115:
2094:
2065:
2036:
2007:
1978:
1959:10.1038/358430a0
1933:
1908:(5068): 369–73.
1892:
1882:
1871:10.1172/JCI20530
1849:
1839:
1812:
1775:
1669:
1668:
1640:
1633:
1616:
1600:
1599:
1591:
1575:
1574:
1571:RefSeq (protein)
1561:
1545:
1544:
1536:
1520:
1519:
1496:
1495:
1477:
1476:
1451:
1450:
1432:
1431:
1406:
1405:
1387:
1386:
1356:
1355:
1085:cell development
681:
680:
667:
658:
651:
644:
637:
636:
622:
602:semi-lunar valve
590:secondary oocyte
562:
560:Top expressed in
555:
554:
532:ventricular zone
512:cartilage tissue
500:
498:Top expressed in
493:
492:
472:
471:
455:
454:
445:
432:
421:
406:
399:
393:
382:
370:
354:
353:
344:
331:
320:
305:
298:
292:
281:
267:
251:
250:
245:
196:
189:
166:
145:
144:
139:
118:
117:
112:
100:
99:
93:
86:
82:
79:
73:
68:this article by
59:inline citations
38:
37:
30:
21:
5307:
5306:
5302:
5301:
5300:
5298:
5297:
5296:
5272:
5271:
5270:
5257:
5256:
5252:
5239:
5238:
5234:
5222:
5213:
5201:
5192:
5188:
5183:
5102:Cerberus (CER1)
5078:
5009:
4981:
4888:Eptotermin alfa
4883:Dibotermin alfa
4824:
4724:Eptotermin alfa
4719:Dibotermin alfa
4639:
4589:Eptotermin alfa
4584:Dibotermin alfa
4539:
4440:
4355:
4300:Eptotermin alfa
4295:Dibotermin alfa
4233:
4088:
3966:
3942:Eptotermin alfa
3937:Dibotermin alfa
3874:
3822:Eptotermin alfa
3744:
3601:
3590:
3560:
3555:
3534:
3496:
3459:
3405:
3400:
3374:
3365:
3358:
3323:
3301:EGF-like domain
3291:
3258:
3253:
3219:
3214:
3163:
3158:
3119:
3105:
3100:
3070:
3065:
3049:
3026:
2963:
2892:
2876:
2838:
2768:
2756:
2618:
2565:TGF beta family
2537:
2528:
2498:
2493:
2490:
2484:
2475:
2469:
2455:
2452:
2422:
2203:Eur. J. Biochem
1945:(6385): 430–4.
1865:(12): 1776–84.
1859:J. Clin. Invest
1745:
1743:Further reading
1678:View/Edit Mouse
1673:View/Edit Human
1636:
1629:
1626:Location (UCSC)
1612:
1608:
1587:
1583:
1557:
1553:
1532:
1528:
1441:ENSG00000092969
1334:
805:eye development
793:
747:
738:protein binding
663:
653:
652:
646:
645:
618:
609:
604:
600:
596:
592:
588:
584:
580:
576:
572:
558:
547:
542:
538:
534:
530:
526:
522:
518:
514:
510:
508:Achilles tendon
496:
440:
427:
419:
409:
408:
407:
400:
380:
357:Gene location (
339:
326:
318:
308:
307:
306:
299:
277:
254:Gene location (
205:
192:
185:
154:
132:
94:
83:
77:
74:
63:
49:related reading
39:
35:
28:
23:
22:
15:
12:
11:
5:
5305:
5295:
5294:
5289:
5284:
5269:
5268:
5250:
5232:
5211:
5189:
5185:
5184:
5182:
5181:
5172:
5171:
5165:
5155:
5154:
5149:
5144:
5139:
5134:
5129:
5124:
5119:
5114:
5109:
5104:
5099:
5090:
5088:
5084:
5083:
5080:
5079:
5077:
5076:
5058:
5044:
5035:
5033:
5021:
5015:
5014:
5011:
5010:
5008:
5007:
4998:
4996:
4983:
4982:
4980:
4979:
4970:
4969:
4955:
4937:
4936:
4931:
4926:
4921:
4916:
4890:
4885:
4880:
4858:
4836:
4834:
4826:
4825:
4823:
4822:
4813:
4812:
4798:
4780:
4779:
4774:
4769:
4764:
4726:
4721:
4716:
4678:
4656:
4654:
4641:
4640:
4638:
4637:
4619:
4618:
4613:
4591:
4586:
4581:
4551:
4549:
4541:
4540:
4538:
4537:
4532:
4523:
4522:
4517:
4512:
4503:
4502:
4484:
4474:
4465:
4463:
4452:
4446:
4445:
4442:
4441:
4439:
4438:
4433:
4428:
4419:
4418:
4400:
4399:
4394:
4372:
4370:
4357:
4356:
4354:
4353:
4348:
4343:
4334:
4333:
4328:
4302:
4297:
4292:
4250:
4248:
4235:
4234:
4232:
4231:
4226:
4221:
4216:
4211:
4206:
4201:
4196:
4191:
4186:
4181:
4176:
4167:
4166:
4161:
4156:
4147:
4146:
4128:
4114:
4105:
4103:
4090:
4089:
4087:
4086:
4081:
4076:
4067:
4066:
4052:
4034:
4033:
4028:
4023:
4005:
3983:
3981:
3968:
3967:
3965:
3964:
3959:
3954:
3945:
3944:
3939:
3934:
3900:
3891:
3889:
3876:
3875:
3873:
3872:
3867:
3862:
3857:
3852:
3843:
3842:
3824:
3819:
3793:
3788:
3783:
3761:
3759:
3746:
3745:
3743:
3742:
3733:
3732:
3723:
3722:
3717:
3708:
3707:
3698:
3697:
3679:
3669:
3664:
3654:
3649:
3627:
3625:
3609:
3603:
3602:
3589:
3588:
3581:
3574:
3566:
3557:
3556:
3554:
3553:
3548:
3542:
3540:
3536:
3535:
3533:
3532:
3527:
3522:
3517:
3512:
3506:
3504:
3498:
3497:
3495:
3494:
3489:
3484:
3479:
3473:
3471:
3465:
3464:
3461:
3460:
3458:
3457:
3456:
3455:
3450:
3445:
3435:
3430:
3425:
3420:
3414:
3412:
3402:
3401:
3399:
3398:
3393:
3387:
3385:
3368:
3366:Relaxin family
3360:
3359:
3357:
3356:
3355:
3354:
3349:
3344:
3333:
3331:
3325:
3324:
3322:
3321:
3316:
3311:
3305:
3303:
3297:
3296:
3293:
3292:
3290:
3289:
3284:
3279:
3274:
3268:
3266:
3255:
3254:
3252:
3251:
3245:
3239:
3233:
3226:
3224:
3216:
3215:
3213:
3212:
3199:
3186:
3172:
3170:
3160:
3159:
3157:
3156:
3143:
3129:
3127:
3113:
3107:
3106:
3103:Growth factors
3099:
3098:
3091:
3084:
3076:
3067:
3066:
3064:
3063:
3057:
3055:
3051:
3050:
3048:
3047:
3042:
3036:
3034:
3028:
3027:
3025:
3024:
3019:
3014:
3009:
3004:
2999:
2994:
2989:
2984:
2979:
2973:
2971:
2965:
2964:
2962:
2961:
2956:
2950:
2941:
2935:
2930:
2925:
2920:
2910:
2908:
2898:
2897:
2894:
2893:
2891:
2890:
2884:
2882:
2878:
2877:
2875:
2874:
2869:
2864:
2863:
2862:
2857:
2846:
2844:
2840:
2839:
2837:
2836:
2835:
2834:
2829:
2819:
2814:
2813:
2812:
2807:
2802:
2791:
2789:
2782:
2762:
2761:
2758:
2757:
2755:
2754:
2749:
2748:
2747:
2742:
2737:
2732:
2727:
2725:Myostatin/GDF8
2722:
2717:
2712:
2707:
2702:
2697:
2687:
2686:
2685:
2680:
2675:
2670:
2665:
2660:
2655:
2650:
2645:
2640:
2629:
2627:
2620:
2619:
2617:
2616:
2611:
2610:
2609:
2604:
2599:
2594:
2584:
2583:
2582:
2577:
2572:
2561:
2559:
2545:
2539:
2538:
2531:Cell signaling
2527:
2526:
2519:
2512:
2504:
2495:
2494:
2492:
2491:
2485:
2478:
2476:
2470:
2463:
2460:
2457:
2456:
2451:
2450:
2443:
2436:
2428:
2421:
2420:
2383:
2346:
2303:
2264:
2244:(6): 2747–54.
2229:
2194:
2159:
2131:(12): 3673–7.
2116:
2095:
2066:
2037:
2008:
1984:Growth Factors
1979:
1934:
1893:
1850:
1813:
1776:
1746:
1744:
1741:
1685:
1684:
1681:
1680:
1675:
1665:
1664:
1658:
1657:
1654:
1653:
1651:
1649:
1642:
1641:
1634:
1627:
1623:
1622:
1619:
1618:
1604:
1603:
1597:
1594:
1593:
1579:
1578:
1572:
1568:
1567:
1564:
1563:
1549:
1548:
1542:
1539:
1538:
1524:
1523:
1517:
1513:
1512:
1509:
1508:
1500:
1499:
1493:
1490:
1489:
1481:
1480:
1474:
1468:
1467:
1464:
1463:
1455:
1454:
1448:
1445:
1444:
1436:
1435:
1429:
1423:
1422:
1419:
1418:
1410:
1409:
1403:
1400:
1399:
1391:
1390:
1384:
1378:
1377:
1372:
1367:
1363:
1362:
1352:
1351:
1348:
1347:
1336:
1335:
1333:
1332:
1327:
1322:
1317:
1312:
1307:
1302:
1297:
1292:
1287:
1282:
1277:
1272:
1267:
1262:
1257:
1252:
1247:
1242:
1237:
1232:
1227:
1222:
1217:
1212:
1207:
1202:
1197:
1192:
1187:
1182:
1177:
1172:
1167:
1162:
1157:
1152:
1147:
1142:
1137:
1132:
1127:
1122:
1117:
1112:
1107:
1102:
1097:
1092:
1087:
1082:
1077:
1072:
1067:
1062:
1060:cell migration
1057:
1052:
1047:
1042:
1037:
1032:
1027:
1022:
1017:
1012:
1007:
1002:
997:
992:
987:
982:
977:
972:
967:
962:
957:
952:
947:
942:
937:
932:
927:
922:
917:
912:
907:
902:
897:
892:
887:
882:
877:
872:
867:
862:
857:
852:
847:
842:
837:
832:
827:
822:
817:
812:
807:
801:
799:
795:
794:
792:
791:
786:
781:
776:
771:
766:
761:
755:
753:
749:
748:
746:
745:
740:
735:
730:
725:
720:
715:
710:
705:
700:
694:
692:
688:
687:
677:
676:
673:
672:
669:
668:
660:
659:
634:
628:
627:
624:
623:
615:
614:
611:
610:
608:
607:
603:
599:
595:
591:
587:
583:
579:
575:
571:
567:
564:
563:
552:
549:
548:
546:
545:
541:
537:
533:
529:
525:
521:
517:
513:
509:
505:
502:
501:
489:
488:
480:
469:
463:
462:
459:RNA expression
451:
450:
447:
446:
438:
434:
433:
425:
422:
417:
411:
410:
401:
394:
388:
384:
383:
378:
372:
371:
363:
362:
350:
349:
346:
345:
337:
333:
332:
324:
321:
316:
310:
309:
300:
293:
287:
283:
282:
275:
269:
268:
260:
259:
247:
246:
203:
199:
198:
190:
182:
181:
177:
176:
173:
172:
169:
168:
150:
149:
141:
140:
129:
123:
122:
114:
113:
105:
104:
96:
95:
53:external links
42:
40:
33:
26:
9:
6:
4:
3:
2:
5304:
5293:
5290:
5288:
5285:
5283:
5280:
5279:
5277:
5264:
5260:
5254:
5246:
5242:
5236:
5229:
5225:
5220:
5218:
5216:
5208:
5204:
5199:
5197:
5195:
5190:
5180:
5177:
5174:
5173:
5169:
5166:
5163:
5160:
5157:
5156:
5153:
5152:Tomoregulin 1
5150:
5148:
5145:
5143:
5140:
5138:
5135:
5133:
5130:
5128:
5127:Gremlin (Drm)
5125:
5123:
5120:
5118:
5115:
5113:
5110:
5108:
5105:
5103:
5100:
5098:
5095:
5092:
5091:
5089:
5085:
5074:
5070:
5066:
5062:
5059:
5056:
5052:
5048:
5045:
5043:
5040:
5037:
5036:
5034:
5032:
5025:
5022:
5020:
5016:
5006:
5003:
5000:
4999:
4997:
4995:
4984:
4978:
4975:
4972:
4971:
4967:
4963:
4959:
4956:
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4902:
4898:
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4891:
4889:
4886:
4884:
4881:
4878:
4874:
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4866:
4862:
4859:
4856:
4852:
4848:
4844:
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4838:
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4833:
4827:
4821:
4818:
4815:
4814:
4810:
4806:
4802:
4799:
4796:
4792:
4788:
4785:
4782:
4781:
4778:
4775:
4773:
4770:
4768:
4765:
4762:
4758:
4754:
4750:
4746:
4742:
4738:
4734:
4730:
4727:
4725:
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4714:
4710:
4706:
4702:
4698:
4694:
4690:
4686:
4682:
4679:
4676:
4672:
4668:
4664:
4661:
4658:
4657:
4655:
4653:
4642:
4635:
4631:
4627:
4624:
4621:
4620:
4617:
4614:
4611:
4607:
4603:
4599:
4595:
4592:
4590:
4587:
4585:
4582:
4579:
4575:
4571:
4567:
4563:
4559:
4556:
4553:
4552:
4550:
4548:
4542:
4536:
4533:
4531:
4528:
4525:
4524:
4521:
4518:
4516:
4513:
4511:
4508:
4505:
4504:
4500:
4496:
4492:
4488:
4485:
4482:
4478:
4475:
4473:
4470:
4467:
4466:
4464:
4462:
4456:
4453:
4451:
4447:
4437:
4434:
4432:
4429:
4427:
4424:
4421:
4420:
4416:
4412:
4408:
4405:
4402:
4401:
4398:
4395:
4392:
4388:
4384:
4380:
4377:
4374:
4373:
4371:
4369:
4358:
4352:
4349:
4347:
4344:
4342:
4339:
4336:
4335:
4332:
4329:
4326:
4322:
4318:
4314:
4310:
4306:
4303:
4301:
4298:
4296:
4293:
4290:
4286:
4282:
4278:
4274:
4270:
4266:
4262:
4258:
4255:
4252:
4251:
4249:
4247:
4236:
4230:
4227:
4225:
4222:
4220:
4217:
4215:
4212:
4210:
4207:
4205:
4202:
4200:
4197:
4195:
4192:
4190:
4187:
4185:
4182:
4180:
4177:
4175:
4172:
4169:
4168:
4165:
4162:
4160:
4157:
4155:
4152:
4149:
4148:
4144:
4140:
4136:
4132:
4129:
4126:
4122:
4118:
4115:
4113:
4110:
4107:
4106:
4104:
4102:
4091:
4085:
4082:
4080:
4077:
4075:
4072:
4069:
4068:
4064:
4060:
4056:
4053:
4050:
4046:
4042:
4039:
4036:
4035:
4032:
4029:
4027:
4024:
4021:
4017:
4013:
4009:
4006:
4003:
3999:
3995:
3991:
3988:
3985:
3984:
3982:
3980:
3969:
3963:
3960:
3958:
3955:
3953:
3950:
3947:
3946:
3943:
3940:
3938:
3935:
3932:
3928:
3924:
3920:
3916:
3912:
3908:
3904:
3901:
3899:
3896:
3893:
3892:
3890:
3888:
3877:
3871:
3868:
3866:
3863:
3861:
3858:
3856:
3853:
3851:
3848:
3845:
3844:
3840:
3836:
3832:
3828:
3825:
3823:
3820:
3817:
3813:
3809:
3805:
3801:
3797:
3794:
3792:
3789:
3787:
3784:
3781:
3777:
3773:
3769:
3766:
3763:
3762:
3760:
3758:
3747:
3741:
3738:
3735:
3734:
3731:
3728:
3725:
3724:
3721:
3718:
3716:
3713:
3710:
3709:
3706:
3705:Ascrinvacumab
3703:
3700:
3699:
3695:
3691:
3687:
3683:
3680:
3677:
3673:
3670:
3668:
3665:
3662:
3658:
3655:
3653:
3650:
3647:
3643:
3639:
3635:
3632:
3629:
3628:
3626:
3624:
3613:
3610:
3608:
3604:
3600:
3597:
3587:
3582:
3580:
3575:
3573:
3568:
3567:
3564:
3552:
3549:
3547:
3544:
3543:
3541:
3537:
3531:
3528:
3526:
3523:
3521:
3518:
3516:
3513:
3511:
3508:
3507:
3505:
3503:
3499:
3493:
3490:
3488:
3485:
3483:
3480:
3478:
3475:
3474:
3472:
3470:
3466:
3454:
3451:
3449:
3446:
3444:
3441:
3440:
3439:
3436:
3434:
3431:
3429:
3426:
3424:
3421:
3419:
3416:
3415:
3413:
3410:
3409:
3403:
3397:
3394:
3392:
3389:
3388:
3386:
3383:
3382:
3378:
3372:
3369:
3367:
3361:
3353:
3350:
3348:
3345:
3343:
3340:
3339:
3338:
3335:
3334:
3332:
3330:
3326:
3320:
3317:
3315:
3312:
3310:
3307:
3306:
3304:
3302:
3298:
3288:
3285:
3283:
3280:
3278:
3275:
3273:
3270:
3269:
3267:
3264:
3261:
3260:hormone-like:
3256:
3249:
3246:
3243:
3240:
3237:
3234:
3231:
3228:
3227:
3225:
3222:
3217:
3211:
3207:
3203:
3200:
3198:
3194:
3190:
3187:
3185:
3181:
3177:
3174:
3173:
3171:
3168:
3167:
3161:
3155:
3151:
3147:
3144:
3142:
3138:
3134:
3131:
3130:
3128:
3125:
3123:
3117:
3114:
3112:
3108:
3104:
3097:
3092:
3090:
3085:
3083:
3078:
3077:
3074:
3062:
3059:
3058:
3056:
3052:
3046:
3043:
3041:
3038:
3037:
3035:
3033:
3029:
3023:
3020:
3018:
3015:
3013:
3010:
3008:
3005:
3003:
3000:
2998:
2995:
2993:
2990:
2988:
2985:
2983:
2980:
2978:
2975:
2974:
2972:
2970:
2966:
2960:
2957:
2954:
2951:
2949:
2945:
2942:
2939:
2936:
2934:
2931:
2929:
2926:
2924:
2921:
2919:
2915:
2912:
2911:
2909:
2907:
2903:
2899:
2889:
2886:
2885:
2883:
2879:
2873:
2870:
2868:
2865:
2861:
2858:
2856:
2853:
2852:
2851:
2848:
2847:
2845:
2841:
2833:
2830:
2828:
2825:
2824:
2823:
2820:
2818:
2815:
2811:
2808:
2806:
2803:
2801:
2798:
2797:
2796:
2793:
2792:
2790:
2786:
2783:
2780:
2776:
2772:
2767:
2763:
2753:
2750:
2746:
2743:
2741:
2738:
2736:
2733:
2731:
2728:
2726:
2723:
2721:
2718:
2716:
2713:
2711:
2708:
2706:
2703:
2701:
2698:
2696:
2693:
2692:
2691:
2688:
2684:
2681:
2679:
2676:
2674:
2671:
2669:
2666:
2664:
2661:
2659:
2656:
2654:
2651:
2649:
2646:
2644:
2641:
2639:
2636:
2635:
2634:
2631:
2630:
2628:
2626:
2621:
2615:
2612:
2608:
2605:
2603:
2600:
2598:
2595:
2593:
2590:
2589:
2588:
2585:
2581:
2578:
2576:
2573:
2571:
2568:
2567:
2566:
2563:
2562:
2560:
2558:
2554:
2549:
2546:
2544:
2540:
2536:
2532:
2525:
2520:
2518:
2513:
2511:
2506:
2505:
2502:
2488:
2482:
2477:
2473:
2467:
2462:
2461:
2458:
2449:
2444:
2442:
2437:
2435:
2430:
2429:
2426:
2417:
2413:
2409:
2405:
2401:
2397:
2393:
2389:
2384:
2380:
2376:
2372:
2368:
2364:
2360:
2357:(4): 411–26.
2356:
2352:
2347:
2343:
2339:
2334:
2329:
2325:
2321:
2318:(4): 557–68.
2317:
2313:
2309:
2304:
2300:
2296:
2291:
2286:
2282:
2278:
2274:
2270:
2265:
2261:
2257:
2252:
2247:
2243:
2239:
2238:J. Biol. Chem
2235:
2230:
2226:
2222:
2217:
2212:
2209:(2): 687–93.
2208:
2204:
2200:
2195:
2191:
2187:
2182:
2177:
2173:
2169:
2168:J. Biol. Chem
2165:
2160:
2156:
2152:
2147:
2142:
2138:
2134:
2130:
2126:
2122:
2117:
2113:
2109:
2106:(4): 323–31.
2105:
2101:
2096:
2092:
2088:
2084:
2080:
2076:
2072:
2067:
2063:
2059:
2055:
2051:
2047:
2043:
2038:
2034:
2030:
2026:
2022:
2018:
2014:
2009:
2005:
2001:
1997:
1993:
1990:(4): 247–55.
1989:
1985:
1980:
1976:
1972:
1968:
1964:
1960:
1956:
1952:
1948:
1944:
1940:
1935:
1931:
1927:
1923:
1919:
1915:
1911:
1907:
1903:
1899:
1894:
1890:
1886:
1881:
1876:
1872:
1868:
1864:
1860:
1856:
1851:
1847:
1843:
1838:
1833:
1830:(4): 179–90.
1829:
1825:
1824:
1819:
1814:
1810:
1806:
1802:
1798:
1794:
1790:
1787:(2): 177–85.
1786:
1782:
1781:J. Neurooncol
1777:
1773:
1769:
1765:
1761:
1757:
1753:
1748:
1747:
1740:
1738:
1737:
1732:
1728:
1724:
1721:
1717:
1713:
1710:
1709:extracellular
1706:
1704:
1699:
1695:
1691:
1679:
1674:
1670:
1666:
1663:
1659:
1652:
1650:
1647:
1643:
1639:
1635:
1632:
1628:
1624:
1617:
1615:
1611:
1605:
1601:
1598:
1592:
1590:
1586:
1580:
1576:
1573:
1569:
1562:
1560:
1556:
1550:
1546:
1543:
1537:
1535:
1531:
1525:
1521:
1518:
1516:RefSeq (mRNA)
1514:
1507:
1506:
1501:
1497:
1494:
1488:
1487:
1482:
1478:
1475:
1473:
1469:
1462:
1461:
1456:
1452:
1449:
1443:
1442:
1437:
1433:
1430:
1428:
1424:
1417:
1416:
1411:
1407:
1404:
1398:
1397:
1392:
1388:
1385:
1383:
1379:
1376:
1373:
1371:
1368:
1364:
1361:
1357:
1353:
1346:
1342:
1337:
1331:
1328:
1326:
1323:
1321:
1318:
1316:
1313:
1311:
1308:
1306:
1303:
1301:
1298:
1296:
1293:
1291:
1288:
1286:
1283:
1281:
1278:
1276:
1273:
1271:
1268:
1266:
1263:
1261:
1258:
1256:
1253:
1251:
1248:
1246:
1243:
1241:
1238:
1236:
1233:
1231:
1228:
1226:
1223:
1221:
1218:
1216:
1213:
1211:
1208:
1206:
1203:
1201:
1198:
1196:
1193:
1191:
1188:
1186:
1183:
1181:
1178:
1176:
1173:
1171:
1168:
1166:
1163:
1161:
1158:
1156:
1153:
1151:
1148:
1146:
1143:
1141:
1138:
1136:
1133:
1131:
1128:
1126:
1123:
1121:
1118:
1116:
1113:
1111:
1108:
1106:
1103:
1101:
1098:
1096:
1093:
1091:
1088:
1086:
1083:
1081:
1078:
1076:
1073:
1071:
1068:
1066:
1063:
1061:
1058:
1056:
1053:
1051:
1048:
1046:
1043:
1041:
1038:
1036:
1033:
1031:
1028:
1026:
1023:
1021:
1018:
1016:
1013:
1011:
1008:
1006:
1003:
1001:
998:
996:
993:
991:
988:
986:
983:
981:
978:
976:
973:
971:
970:odontogenesis
968:
966:
963:
961:
958:
956:
953:
951:
950:wound healing
948:
946:
943:
941:
938:
936:
933:
931:
928:
926:
923:
921:
918:
916:
913:
911:
908:
906:
903:
901:
898:
896:
893:
891:
888:
886:
883:
881:
878:
876:
873:
871:
868:
866:
863:
861:
858:
856:
853:
851:
848:
846:
843:
841:
838:
836:
833:
831:
828:
826:
823:
821:
818:
816:
813:
811:
808:
806:
803:
802:
800:
797:
796:
790:
787:
785:
782:
780:
777:
775:
772:
770:
767:
765:
762:
760:
757:
756:
754:
751:
750:
744:
741:
739:
736:
734:
731:
729:
726:
724:
721:
719:
716:
714:
711:
709:
706:
704:
701:
699:
696:
695:
693:
690:
689:
686:
685:Gene ontology
682:
678:
666:
661:
657:
650:
643:
638:
635:
633:
629:
621:
616:
605:
601:
597:
593:
589:
585:
581:
577:
573:
569:
568:
565:
561:
556:
553:
543:
539:
535:
531:
527:
523:
519:
515:
511:
507:
506:
503:
499:
494:
491:
490:
487:
485:
481:
479:
478:
474:
473:
470:
468:
464:
460:
456:
452:
444:
439:
435:
431:
426:
416:
412:
405:
398:
392:
385:
377:
373:
369:
364:
360:
355:
351:
343:
338:
334:
330:
325:
315:
311:
304:
297:
291:
284:
280:
274:
270:
266:
261:
257:
252:
248:
244:
240:
236:
232:
228:
224:
220:
216:
212:
208:
200:
195:
188:
183:
178:
167:
165:
161:
157:
151:
146:
143:
142:
138:
135:
128:
124:
119:
115:
111:
106:
101:
92:
89:
81:
71:
67:
61:
60:
54:
50:
46:
41:
32:
31:
19:
5262:
5253:
5244:
5235:
5175:
5158:
5093:
5068:
5038:
5001:
4973:
4941:Antagonists:
4940:
4839:
4816:
4784:Antagonists:
4783:
4659:
4623:Antagonists:
4622:
4554:
4526:
4515:Lerdelimumab
4510:Fresolimumab
4506:
4494:
4468:
4422:
4404:Antagonists:
4403:
4375:
4337:
4253:
4170:
4159:Lerdelimumab
4154:Fresolimumab
4150:
4138:
4108:
4070:
4038:Antagonists:
4037:
3986:
3948:
3894:
3846:
3834:
3764:
3736:
3730:Dalantercept
3726:
3711:
3701:
3689:
3630:
3406:
3375:
3364:Insulin/IGF/
3346:
3329:TGFβ pathway
3259:
3220:
3164:
3122:FGF receptor
3120:
2574:
2486:
2471:
2394:(1): 153–9.
2391:
2387:
2354:
2350:
2315:
2312:J. Cell Biol
2311:
2272:
2241:
2237:
2206:
2202:
2171:
2167:
2128:
2124:
2103:
2100:Oncogene Res
2099:
2074:
2070:
2048:(7): 493–7.
2045:
2041:
2019:(2): 890–7.
2016:
2012:
1987:
1983:
1942:
1938:
1905:
1901:
1862:
1858:
1827:
1821:
1784:
1780:
1758:(3): 293–8.
1755:
1751:
1734:
1729:of the same
1712:glycosylated
1707:). It is an
1703:Glioblastoma
1701:
1689:
1688:
1610:NP_001316036
1607:
1585:NP_001129071
1582:
1559:NM_001329107
1552:
1534:NM_001135599
1527:
1503:
1484:
1458:
1439:
1413:
1394:
1374:
1369:
850:angiogenesis
578:ciliary body
482:
475:
441:186,438,186
428:186,354,989
340:218,444,619
327:218,345,336
202:External IDs
153:
84:
75:
64:Please help
56:
5292:TGFβ domain
5159:Antibodies:
5122:Follistatin
4977:Ramatercept
4820:Sotatercept
4520:Metelimumab
4507:Antibodies:
4164:Metelimumab
4151:Antibodies:
3740:Disitertide
3702:Antibodies:
3032:Coreceptors
2992:Follistatin
2902:Transducers
2454:PDB gallery
1716:interleukin
1175:hemopoiesis
180:Identifiers
70:introducing
5276:Categories
5230:, May 2017
5209:, May 2017
5162:Stamulumab
5112:DAN (PARN)
5031:(β-glycan)
4934:Radotermin
4777:Radotermin
4757:11 (BMP11)
4713:15 (GDF9B)
4616:Radotermin
4481:10 (BMP3B)
4391:11 (BMP11)
4331:Radotermin
4289:15 (GDF9B)
4194:LY-2109761
4125:11 (BMP11)
4121:10 (BMP3B)
4020:11 (BMP11)
3599:modulators
3551:Hepatocyte
3111:Fibroblast
2888:betaglycan
2623:Ligand of
2551:Ligand of
2273:Biochem. J
2077:(1): 1–8.
1718:dependent
820:cell death
486:(ortholog)
223:HomoloGene
78:March 2019
5042:Avotermin
5005:AMH (MIS)
5002:Agonists:
4913:7 (BMP12)
4909:6 (BMP13)
4905:5 (BMP14)
4840:Agonists:
4749:7 (BMP12)
4745:6 (BMP13)
4741:5 (BMP14)
4660:Agonists:
4610:7 (BMP12)
4606:6 (BMP13)
4602:5 (BMP14)
4555:Agonists:
4535:LY-364947
4472:Avotermin
4469:Agonists:
4436:SB-505124
4431:SB-431542
4376:Agonists:
4317:7 (BMP12)
4313:6 (BMP13)
4309:5 (BMP14)
4254:Agonists:
4224:SB-525334
4219:SB-505124
4214:SB-431542
4189:LY-364947
4184:GW-788388
4112:Avotermin
4109:Agonists:
4084:SB-505124
4079:SB-431542
3987:Agonists:
3898:AMH (MIS)
3895:Agonists:
3791:Avotermin
3786:AMH (MIS)
3765:Agonists:
3652:Avotermin
3631:Agonists:
1614:NP_033393
1589:NP_003229
1555:NM_009367
1530:NM_003238
1360:Orthologs
231:GeneCards
5287:Proteins
5226:–
5205:–
5179:Endoglin
5087:Unsorted
5039:Ligands:
5019:Type III
4598:2 (BMP9)
4204:R-268712
3676:2 (BMP9)
3667:Cetermin
3263:FGF15/19
3124:ligands:
2977:Cerberus
2416:21284888
2408:10457363
2379:85850306
1889:14679171
1846:11795478
1809:21461718
1801:11716069
1694:cytokine
1662:Wikidata
1339:Sources:
5228:Ensembl
5207:Ensembl
5176:Others:
5117:Decorin
5107:Chordin
5047:Inhibin
4944:Inhibin
4843:Activin
4787:Inhibin
4663:Activin
4626:Inhibin
4450:Type II
4426:A 83-01
4351:K-02288
4174:A 83-01
4074:A 83-01
4041:Inhibin
3990:Activin
3962:K-02288
3865:K-02288
3768:Activin
3715:K-02288
3634:Activin
3438:Relaxin
3377:Insulin
2997:Gremlin
2987:Decorin
2982:Chordin
2881:TGFBR3:
2843:TGFBR2:
2788:TGFBR1:
2771:Activin
2371:9493905
2342:8106553
2333:2119924
2299:8093006
2290:1137259
2260:7852346
2225:7513640
2190:3476488
2155:3322813
2112:3226728
2091:3162414
2062:2850146
2033:2119582
2004:1764261
1975:4239431
1967:1641027
1947:Bibcode
1930:1631557
1910:Bibcode
1902:Science
1772:9611771
1733:(i.e.,
1472:UniProt
1427:Ensembl
1366:Species
1345:QuickGO
574:decidua
461:pattern
187:Aliases
66:improve
5168:TRC105
5137:Noggin
5029:TGFβR3
4831:ACVR2B
4646:ACVR2A
4460:TGFβR2
4366:ACVR1C
4244:BMPR1B
4229:SD-208
4179:D-4476
4099:TGFβR1
3977:ACVR1B
3885:BMPR1A
3755:ACVR1A
3621:ACVRL1
3607:Type I
3525:VEGF-D
3520:VEGF-C
3515:VEGF-B
3510:VEGF-A
3319:HB-EGF
3250:(FHF4)
3244:(FHF2)
3238:(FHF1)
3232:(FHF3)
3045:Cripto
3012:Noggin
2944:I-SMAD
2914:R-SMAD
2860:ACVR2B
2855:ACVR2A
2832:BMPR1B
2827:BMPR1A
2817:ACVRL1
2810:ACVR1C
2805:ACVR1B
2779:family
2580:TGF-β3
2575:TGF-β2
2570:TGF-β1
2414:
2406:
2377:
2369:
2340:
2330:
2297:
2287:
2258:
2223:
2188:
2153:
2146:553836
2143:
2125:EMBO J
2110:
2089:
2060:
2031:
2002:
1973:
1965:
1939:Nature
1928:
1887:
1880:297008
1877:
1844:
1807:
1799:
1770:
1723:tumors
1720:T-cell
1648:search
1646:PubMed
1505:P27090
1486:P61812
1382:Entrez
632:BioGPS
211:190220
5132:LTBP1
5097:BAMBI
4988:AMHR2
4958:Lefty
4924:Nodal
4801:Lefty
4772:Nodal
4650:ACVR2
4546:BMPR2
4530:DMH-2
4407:Lefty
4397:Nodal
4341:DMH-2
4055:Lefty
4031:Nodal
3952:DMH-2
3855:DMH-2
3850:DMH-1
3546:Nerve
3539:Other
3492:PDGFD
3487:PDGFC
3482:PDGFB
3477:PDGFA
3433:INSL6
3428:INSL5
3423:INSL4
3418:INSL3
3352:TGFβ3
3347:TGFβ2
3342:TGFβ1
3287:FGF23
3282:FGF21
3277:FGF19
3272:FGF15
3248:FGF14
3242:FGF13
3236:FGF12
3230:FGF11
3210:FGF20
3206:FGF16
3197:FGF18
3193:FGF17
3184:FGF22
3180:FGF10
3054:Other
3040:BAMBI
3022:THBS1
3007:LTBP1
3002:Lefty
2959:SMAD4
2953:SMAD7
2948:SMAD6
2938:SMAD9
2933:SMAD5
2928:SMAD3
2923:SMAD2
2918:SMAD1
2872:BMPR2
2867:AMHR2
2822:BMPR1
2800:ACVR1
2745:GDF15
2740:GDF11
2735:GDF10
2683:BMP15
2678:BMP10
2673:BMP8b
2668:BMP8a
2614:Nodal
2607:INHBC
2602:INHBB
2597:INHBA
2557:TGFBR
2412:S2CID
2375:S2CID
1971:S2CID
1805:S2CID
1736:TGFB2
1415:21808
1375:Mouse
1370:Human
1341:Amigo
536:tibia
524:sperm
484:Mouse
477:Human
424:Start
359:Mouse
323:Start
256:Human
235:TGFB2
219:98726
194:TGFB2
103:TGFB2
51:, or
18:TGFB2
5142:TGIF
5061:TGFβ
4992:AMHR
4487:TGFβ
4362:ALK7
4240:ALK6
4131:TGFβ
4095:ALK5
3973:ALK4
3881:ALK3
3827:TGFβ
3751:ALK2
3682:TGFβ
3617:ALK1
3594:TGFβ
3396:IGF2
3391:IGF1
3379:and
3337:TGFβ
3309:TGFα
3202:FGF9
3189:FGF8
3176:FGF7
3154:FGF6
3150:FGF4
3146:FGF3
3141:FGF5
3137:FGF2
3133:FGF1
3061:SARA
3017:PARN
2906:SMAD
2730:GDF9
2720:GDF7
2715:GDF6
2710:GDF5
2705:GDF3
2700:GDF2
2695:GDF1
2663:BMP7
2658:BMP6
2653:BMP5
2648:BMP4
2643:BMP3
2638:BMP2
2625:BMPR
2592:INHA
2553:ACVR
2487:2tgi
2472:1tfg
2404:PMID
2367:PMID
2338:PMID
2295:PMID
2256:PMID
2221:PMID
2186:PMID
2151:PMID
2108:PMID
2087:PMID
2058:PMID
2029:PMID
2000:PMID
1963:PMID
1926:PMID
1885:PMID
1842:PMID
1797:PMID
1768:PMID
1731:gene
1396:7042
779:axon
582:iris
467:Bgee
415:Band
376:Chr.
319:1q41
314:Band
273:Chr.
227:2432
207:OMIM
164:4KXZ
160:2TGI
156:1TFG
137:RCSB
134:PDBe
4893:GDF
4861:BMP
4729:GDF
4681:BMP
4594:GDF
4558:BMP
4477:GDF
4379:GDF
4305:GDF
4257:BMP
4117:GDF
4008:GDF
3903:BMP
3796:BMP
3672:GDF
3657:BMP
3530:PGF
3314:EGF
3166:KGF
2775:BMP
2555:or
2396:doi
2392:181
2359:doi
2328:PMC
2320:doi
2316:124
2285:PMC
2277:doi
2246:doi
2242:270
2211:doi
2207:221
2176:doi
2172:262
2141:PMC
2133:doi
2079:doi
2071:DNA
2050:doi
2042:DNA
2021:doi
2017:171
1992:doi
1955:doi
1943:358
1918:doi
1906:257
1875:PMC
1867:doi
1863:112
1832:doi
1789:doi
1760:doi
1739:).
437:End
336:End
239:OMA
215:MGI
127:PDB
5278::
5261:.
5243:.
5214:^
5193:^
5071:,
5067:,
5053:,
4964:,
4950:,
4911:,
4907:,
4903:,
4899:,
4875:,
4871:,
4867:,
4855:AB
4853:,
4849:,
4807:,
4793:,
4761:15
4759:,
4755:,
4751:,
4747:,
4743:,
4739:,
4735:,
4711:,
4709:8B
4707:,
4705:8A
4703:,
4699:,
4695:,
4691:,
4687:,
4675:AB
4673:,
4669:,
4632:,
4608:,
4604:,
4600:,
4578:10
4576:,
4572:,
4568:,
4564:,
4497:,
4493:,
4413:,
4389:,
4385:,
4325:15
4323:,
4319:,
4315:,
4311:,
4287:,
4285:8B
4283:,
4281:8A
4279:,
4275:,
4271:,
4267:,
4263:,
4141:,
4137:,
4123:,
4061:,
4047:,
4018:,
4014:,
4002:AB
4000:,
3996:,
3931:8B
3929:,
3927:8A
3925:,
3921:,
3917:,
3913:,
3909:,
3837:,
3833:,
3816:8B
3814:,
3812:8A
3810:,
3806:,
3802:,
3780:AB
3778:,
3774:,
3692:,
3688:,
3661:10
3646:AB
3644:,
3640:,
2777:,
2773:,
2533::
2410:.
2402:.
2390:.
2373:.
2365:.
2355:68
2353:.
2336:.
2326:.
2314:.
2310:.
2293:.
2283:.
2271:.
2254:.
2240:.
2236:.
2219:.
2205:.
2201:.
2184:.
2170:.
2166:.
2149:.
2139:.
2127:.
2123:.
2102:.
2085:.
2073:.
2056:.
2044:.
2027:.
2015:.
1998:.
1986:.
1969:.
1961:.
1953:.
1941:.
1924:.
1916:.
1904:.
1900:.
1883:.
1873:.
1861:.
1857:.
1840:.
1828:33
1826:.
1820:.
1803:.
1795:.
1785:53
1783:.
1766:.
1756:30
1754:.
1343:/
443:bp
430:bp
342:bp
329:bp
237:;
233::
229:;
225::
221:;
217::
213:;
209::
162:,
158:,
55:,
47:,
5265:.
5247:.
5075:)
5073:3
5069:2
5065:1
5063:(
5057:)
5055:B
5051:A
5049:(
4994:)
4990:(
4968:)
4966:2
4962:1
4960:(
4954:)
4952:B
4948:A
4946:(
4915:)
4901:3
4897:1
4895:(
4879:)
4877:7
4873:6
4869:4
4865:2
4863:(
4857:)
4851:B
4847:A
4845:(
4811:)
4809:2
4805:1
4803:(
4797:)
4795:B
4791:A
4789:(
4763:)
4753:9
4737:3
4733:1
4731:(
4715:)
4701:7
4697:6
4693:5
4689:4
4685:2
4683:(
4677:)
4671:B
4667:A
4665:(
4652:)
4648:(
4636:)
4634:B
4630:A
4628:(
4612:)
4596:(
4580:)
4574:7
4570:6
4566:4
4562:2
4560:(
4501:)
4499:3
4495:2
4491:1
4489:(
4483:)
4479:(
4417:)
4415:2
4411:1
4409:(
4393:)
4387:3
4383:1
4381:(
4368:)
4364:(
4327:)
4321:9
4307:(
4291:)
4277:7
4273:6
4269:5
4265:4
4261:2
4259:(
4246:)
4242:(
4145:)
4143:3
4139:2
4135:1
4133:(
4127:)
4119:(
4101:)
4097:(
4065:)
4063:2
4059:1
4057:(
4051:)
4049:B
4045:A
4043:(
4022:)
4016:3
4012:1
4010:(
4004:)
3998:B
3994:A
3992:(
3979:)
3975:(
3933:)
3923:7
3919:6
3915:5
3911:4
3907:2
3905:(
3887:)
3883:(
3841:)
3839:3
3835:2
3831:1
3829:(
3818:)
3808:7
3804:6
3800:5
3798:(
3782:)
3776:B
3772:A
3770:(
3757:)
3753:(
3696:)
3694:3
3690:2
3686:1
3684:(
3678:)
3674:(
3663:)
3659:(
3648:)
3642:B
3638:A
3636:(
3623:)
3619:(
3585:e
3578:t
3571:v
3453:3
3448:2
3443:1
3208:/
3204:/
3195:/
3191:/
3182:/
3178:/
3152:/
3148:/
3139:/
3135:/
3095:e
3088:t
3081:v
2955:)
2946:(
2940:)
2916:(
2904:/
2781:)
2769:(
2523:e
2516:t
2509:v
2447:e
2440:t
2433:v
2418:.
2398::
2381:.
2361::
2344:.
2322::
2301:.
2279::
2262:.
2248::
2227:.
2213::
2192:.
2178::
2157:.
2135::
2129:6
2114:.
2104:3
2093:.
2081::
2075:7
2064:.
2052::
2046:7
2035:.
2023::
2006:.
1994::
1988:4
1977:.
1957::
1949::
1932:.
1920::
1912::
1891:.
1869::
1848:.
1834::
1811:.
1791::
1774:.
1762::
361:)
258:)
241::
91:)
85:(
80:)
76:(
62:.
20:)
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