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Syncope (medicine)

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1202: 1178: 1166: 858:. The most susceptible individuals are elderly frail individuals, or persons who are dehydrated from hot environments or inadequate fluid intake. For example, medical students would be at risk for orthostatic hypotensive syncope while observing long surgeries in the operating room. There is also evidence that exercise training can help reduce orthostatic intolerance. More serious orthostatic hypotension is often the result of certain commonly prescribed medications such as diuretics, β-adrenergic blockers, other anti-hypertensives (including vasodilators), and 520:
under the umbrella of vasovagal syncope related by the same central mechanism. First, the person is usually predisposed to decreased blood pressure by various environmental factors. A lower than expected blood volume, for instance, from taking a low-salt diet in the absence of any salt-retaining tendency. Or heat causing vaso-dilation and worsening the effect of the relatively insufficient blood volume. The next stage is the adrenergic response. If there is underlying fear or anxiety (e.g., social circumstances), or acute fear (e.g., acute threat,
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weakness of the legs causes most people to sit or lie down if there is time to do so. This may avert a complete collapse, but whether the patient sits down or falls down, the result of an ischaemic episode is a posture in which less blood pressure is required to achieve adequate blood flow. An individual with very little skin pigmentation may appear to have all color drained from his or her face at the onset of an episode. This effect combined with the following collapse can make a strong and dramatic impression on bystanders.
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history of congestive heart failure, family history of sudden cardiac death, shortness of breath, HCT<30, hypotension or evidence of bleeding should be admitted to the hospital for further evaluation and monitoring. Low-risk cases of vasovagal or orthostatic syncope in younger people with no significant cardiac history, no family history of sudden unexplained death, and a normal EKG and initial evaluation may be candidates for discharge to follow-up with their primary care provider.
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pressure back to baseline. Apparently healthy individuals may experience minor symptoms ("lightheadedness", "greying-out") as they stand up if blood pressure is slow to respond to the stress of upright posture. If the blood pressure is not adequately maintained during standing, faints may develop. However, the resulting "transient orthostatic hypotension" does not necessarily signal any serious underlying disease. It is as common or perhaps even more common than vasovagal syncope.
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quiet place. For individuals who have problems with chronic fainting spells, therapy should focus on recognizing the triggers and learning techniques to keep from fainting. At the appearance of warning signs such as lightheadedness, nausea, or cold and clammy skin, counter-pressure maneuvers that involve gripping fingers into a fist, tensing the arms, and crossing the legs or squeezing the thighs together can be used to ward off a fainting spell. After the symptoms have passed,
68: 3212:"AHA/ACCF Scientific Statement on the Evaluation of Syncope: From the American Heart Association Councils on Clinical Cardiology, Cardiovascular Nursing, Cardiovascular Disease in the Young, and Stroke, and the Quality of Care and Outcomes Research Interdisciplinary Working Group; and the American College of Cardiology Foundation: In Collaboration with the Heart Rhythm Society: Endorsed by the American Autonomic Society" 1190: 532:. The high (ineffective) sympathetic activity is thereby modulated by vagal (parasympathetic) outflow leading to excessive slowing of heart rate. The abnormality lies in this excessive vagal response causing loss of blood flow to the brain. The tilt-table test typically evokes the attack. Avoiding what brings on the syncope and possibly greater salt intake is often all that is needed. 299:, blurred vision, nausea, vomiting, or feeling warm. Syncope may also be associated with a short episode of muscle twitching. Psychiatric causes can also be determined when a patient experiences fear, anxiety, or panic; particularly before a stressful event, usually medical in nature. When consciousness and muscle strength are not completely lost, it is called 768:
by an abnormal nervous system reaction similar to the reflex faints. Women are significantly more likely to experience syncope as a presenting symptom of a myocardial infarction. In general, faints caused by structural disease of the heart or blood vessels are particularly important to recognize, as they are warning of potentially life-threatening conditions.
1013:(ECG) are the most effective ways to determine the underlying cause of syncope. Guidelines from the American College of Emergency Physicians and American Heart Association recommend a syncope workup include a thorough medical history, physical exam with orthostatic vitals, and a 12-lead ECG. The ECG is useful to detect an abnormal heart rhythm, 608:), and following exercise. Manisty et al. note: "Deglutition syncope is characterised by loss of consciousness on swallowing; it has been associated not only with ingestion of solid food, but also with carbonated and ice-cold beverages, and even belching." Fainting can occur in "cough syncope" following severe fits of 524:), the vaso-motor centre demands an increased pumping action by the heart (flight or fight response). This is set in motion via the adrenergic (sympathetic) outflow from the brain, but the heart is unable to meet requirements because of the low blood volume, or decreased return. A feedback response to the 1336:
Of those presenting with syncope to an emergency department, about 4% died in the next 30 days. The risk of a poor outcome, however, depends very much on the underlying cause. Situational syncope is not at increased risk of death or adverse outcomes. Cardiac syncope is associated with worse prognosis
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Hyperadrenergic orthostatic hypotension refers to an orthostatic drop in blood pressure despite high levels of sympathetic adrenergic response. This occurs when a person with normal physiology is unable to compensate for >20% loss in intravascular volume. This may be due to blood loss, dehydration
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Isolated episodes of loss of consciousness, unheralded by any warning symptoms for more than a few moments. These tend to occur in the adolescent age group and may be associated with fasting, exercise, abdominal straining, or circumstances promoting vaso-dilation (e.g., heat, alcohol). The subject is
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was developed to isolate people who have higher risk for a serious cause of syncope. High risk is anyone who has: congestive heart failure, hematocrit <30%, electrocardiograph abnormality, shortness of breath, or systolic blood pressure <90 mmHg. The San Francisco syncope rule however was
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may be used. This is a portable ECG device that can record the wearer's heart rhythms during daily activities over an extended period of time. Since fainting usually does not occur upon command, a Holter monitor can provide a better understanding of the heart's activity during fainting episodes. For
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can cause "a release of histamine, resulting in an extreme dilatation of the blood vessels, resulting in a drop of blood pressure so that not enough blood reaches the brain, leading to dizziness, fainting, syncope, itching, hives, tingling or swelling of the lips, tongue, or throat; chest tightness,
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episode may also proceed faster than the respiratory system can respond. These processes cause the typical symptoms of fainting: pale skin, rapid breathing, nausea, and weakness of the limbs, particularly of the legs. If the ischemia is intense or prolonged, limb weakness progresses to collapse. The
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suddenly collapsed and died during a televised intercollegiate basketball game. He had previously collapsed during a game a few months prior. He was diagnosed with exercise-induced ventricular tachycardia at the time. There was speculation that he had since stopped taking the prescribed medications
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Syncope affects about three to six out of every thousand people each year. It is more common in older people and females. It is the reason for 2–5% of visits to emergency departments and admissions to hospital. Up to half of women over the age of 80 and a third of medical students describe at least
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Management of syncope focuses on treating the underlying cause. This can be challenging as the underlying cause is unclear in half of all cases. Several risk stratification tools (explained below) have been developed to combat the vague nature of this diagnosis. People with an abnormal ECG reading,
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in the walls of vessels in the carotid sinus and aortic arch. These receptors then trigger a sympathetic nervous response to compensate and redistribute blood back into the brain. The sympathetic response causes peripheral vasoconstriction and increased heart rate. These together act to raise blood
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Diseases involving the shape and strength of the heart can be a cause of reduced blood flow to the brain, which increases risk for syncope. The most common cause in this category is fainting associated with an acute myocardial infarction or ischemic event. The faint in this case is primarily caused
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arises from retrograde (reversed) flow of blood in the vertebral artery or the internal thoracic artery, due to a proximal stenosis (narrowing) and/or occlusion of the subclavian artery. Symptoms such as syncope, lightheadedness, and paresthesias occur while exercising the arm on the affected side
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Vasovagal (situational) syncope is one of the most common types which may occur in response to any of a variety of triggers, such as scary, embarrassing or uneasy situations, during blood drawing, or moments of sudden unusually high stress. There are many different syncope syndromes which all fall
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The Canadian syncope risk score was developed to help select low-risk people that may be viable for discharge home. A score of <0 on the Canadian syncope risk score is associated with <2% risk of serious adverse event within 30 days. It has been shown to be more effective than older syncope
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Syncope affects about three to six out of every thousand people each year. It is more common in older people and females. It is the reason for one to three percent of visits to emergency departments and admissions to hospital. Up to half of women over the age of 80 and a third of medical students
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There are 18.1–39.7 syncope episodes per 1000 people in the general population. Rates are highest between the ages of 10–30 years old. This is likely because of the high rates of vasovagal syncope in the young adult population. Older adults are more likely to have orthostatic or cardiac syncope.
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Recommended acute treatment of vasovagal and orthostatic (hypotension) syncope involves returning blood to the brain by positioning the person on the ground, with legs slightly elevated or sitting leaning forward and the head between the knees for at least 10–15 minutes, preferably in a cool and
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Hypoadrenergic orthostatic hypotension occurs when the person is unable to sustain a normal sympathetic response to blood pressure changes during movement despite adequate intravascular volume. There is little to no compensatory increase in heart rate or blood pressure when standing for up to 10
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are the most common examples. Major valves of the heart become stiffened and reduce the efficiency of the hearts pumping action. This may not cause symptoms at rest but with exertion, the heart is unable to keep up with increased demands leading to syncope. Aortic stenosis presents with repeated
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occurs when heat exposure causes decreased blood volume and peripheral vasodilatation. Position changes, especially during vigorous exercise in the heat, may lead to decreased blood flow to the brain. Closely related to other causes of syncope related to hypotension (low blood pressure) such as
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There also seems to be a genetic component to syncope. A recent genetic study has identified first risk locus for syncope and collapse. The lead genetic variant, residing at chromosome 2q31.1, is an intergenic variant approximately 250 kb downstream of the ZNF804A gene. The variant effected the
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Recurrent syncope with complex associated symptoms. This is neurally mediated syncope (NMS). It is associated with any of the following: preceding or succeeding sleepiness, preceding visual disturbance ("spots before the eyes"), sweating, lightheadedness. The subject is usually but not always
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is recommended. Lifestyle modifications are important for treating people experiencing repeated syncopal episodes. Avoiding triggers and situations where loss of consciousness would be seriously hazardous (operating heavy machinery, commercial pilot, etc.) has been shown to be effective.
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Associated symptoms may be felt in the minutes leading up to a vasovagal episode and are referred to as the prodrome. These consist of light-headedness, confusion, pallor, nausea, salivation, sweating, tachycardia, blurred vision, and sudden urge to defecate among other symptoms.
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originate in the ventricles. VT causes syncope and can result in sudden death. Ventricular tachycardia, which describes a heart rate of over 100 beats per minute with at least three irregular heartbeats as a sequence of consecutive premature beats, can degenerate into
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which increased survival from attackers and might have slowed blood loss in a primitive environment. "Blood-injury phobia", as this is called, is experienced by about 15% of people. It is often possible to manage these symptoms with specific behavioral techniques.
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D'Ascenzo F, Biondi-Zoccai G, Reed MJ, Gabayan GZ, Suzuki M, Costantino G, et al. (2013-07-15). "Incidence, etiology and predictors of adverse outcomes in 43,315 patients presenting to the Emergency Department with syncope: An international meta-analysis".
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is caused primarily by an excessive drop in blood pressure when standing up from a previous position of lying or sitting down. When the head is elevated above the feet the pull of gravity causes blood pressure in the head to drop. This is sensed by
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Seizures and syncope can be difficult to differentiate. Both often present as sudden loss of consciousness and convulsive movements may be present or absent in either. Movements in syncope are typically brief and more irregular than seizures.
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compared to noncardiac syncope. Factors associated with poor outcomes include history of heart failure, history of myocardial infarction, ECG abnormalities, palpitations, signs of hemorrhage, syncope during exertion, and advanced age.
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describe at least one event at some point in their lives. Of those presenting with syncope to an emergency department, about 4% died in the next 30 days. The risk of a poor outcome, however, depends very much on the underlying cause.
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Typically, tachycardic-generated syncope is caused by a cessation of beats following a tachycardic episode. This condition, called tachycardia-bradycardia syndrome, is usually caused by sinoatrial node dysfunction or block or
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If fainting spells occur often without a triggering event, syncope may be a sign of an underlying heart disease. In the case where syncope is caused by cardiac disease, the treatment is much more sophisticated than that of
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Based on this initial workup many physicians will tailor testing and determine whether a person qualifies as 'high-risk', 'intermediate risk' or 'low-risk' based on risk stratification tools. More specific tests such as
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people with more than two episodes of syncope and no diagnosis on "routine testing", an insertable cardiac monitor might be used. It lasts 28–36 months and is inserted just beneath the skin in the upper chest area.
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is a cardiac syncope that occurs with seizures caused by complete or incomplete heart block. Symptoms include deep and fast respiration, weak and slow pulse, and respiratory pauses that may last for 60 seconds.
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Arterial disease in the upper spinal cord, or lower brain that causes syncope if there is a reduction in blood supply. This may occur with extending the neck or with use of medications to lower blood pressure.
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Much of this pathway was discovered in animal experiments by Bezold (Vienna) in the 1860s. In animals, it may represent a defense mechanism when confronted by danger ("playing possum"). A 2023 study identified
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can present with sudden loss of postural tone without associated tonic-clonic movements. Absence of a long post-ictal state is indicative of syncope rather than an akinetic seizure. Some rare forms, such as
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is pressed. The third type of syncope is due to a drop in blood pressure when changing position such as when standing up. This is often due to medications that a person is taking but may also be related to
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and ischemia testing may be recommended for cases where initial evaluation and ECG testing is nondiagnostic. For people with uncomplicated syncope (without seizures and a normal neurological exam)
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Syncope has been linked with psychological triggers. This includes fainting in response to the sight or thought of blood, needles, pain, and other emotionally stressful situations. One theory in
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and some psychiatric disorders among others. Treatment depends on the underlying cause. Those who are considered at high risk following investigation may be admitted to hospital for further
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and some psychiatric disorders among others. Treatment depends on the underlying cause. Those who are considered at high risk following investigation may be admitted to hospital for further
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Albassam OT, Redelmeier RJ, Shadowitz S, Husain AM, Simel D, Etchells EE (25 June 2019). "Did This Patient Have Cardiac Syncope?: The Rational Clinical Examination Systematic Review".
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may be seen following the event in those with pulmonary embolism. Routine broad panel laboratory testing detects abnormalities in <2–3% of results and is therefore not recommended.
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inappropriately leading to poor blood flow to the brain. This may occur from either a triggering event such as exposure to blood, pain, strong feelings, or a specific activity such as
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is performed to elicit orthostatic syncope secondary to autonomic dysfunction (neurogenic). A number of factors make a heart related cause more likely including age over 35, prior
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as a cause of syncope also is not indicated. Although sometimes investigated as a cause of syncope, carotid artery problems are unlikely to cause that condition. Additionally an
576:. A non-combatant who has fainted signals that they are not a threat. This would explain the association between fainting and stimuli such as bloodletting and injuries seen in 3493:
Birnbaum A, Esses D, Bijur P, Wollowitz A, Gallagher EJ (August 2008). "Failure to validate the San Francisco Syncope Rule in an independent emergency department population".
3247:"Guidelines for the diagnosis and management of syncope (version 2009): The Task Force for the Diagnosis and Management of Syncope of the European Society of Cardiology (ESC)" 2261: 955:
Subarachnoid hemorrhage may result in syncope. Often this is in combination with sudden, severe headache. It may occur as a result of a ruptured aneurysm or head trauma.
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Singh J.R., Rand E.B., Erosa S.C., Cho R.S., Sein M. Aromatherapy for Procedural Anxiety in Pain Management and Interventional Spine Procedures: A Randomized Trial.
1139:(ARVD/C). Signs of HCM include large voltages in the precordial leads, repolarization abnormalities, and a wide QRS with a slurred upstroke. Signs of ARVD/C include 3639: 3458:
Quinn J, McDermott D, Stiell I, Kohn M, Wells G (May 2006). "Prospective validation of the San Francisco Syncope Rule to predict patients with serious outcomes".
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Moya A, European Society of Cardiology (ESC), Sutton R, European Heart Rhythm Association (EHRA), Ammirati F, and Heart Rhythm Society (HRS), et al. (2009).
3403:"Incidence, etiology and predictors of adverse outcomes in 43,315 patients presenting to the Emergency Department with syncope: An international meta-analysis" 3192: 2486:
Oqab Z, Ganshorn H, Sheldon R (September 2017). "Prevalence of pulmonary embolism in patients presenting with syncope. A systematic review and meta-analysis".
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Among other conditions prone to trigger syncope (by either hemodynamic compromise or by a neural reflex mechanism, or both), some of the most important are
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rhythm) wherein the heart beats too slowly, too rapidly, or too irregularly to pump enough blood to the brain. Some arrhythmias can be life-threatening.
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Nallamothu BK, Mehta RH, Saint S, et al. (October 2002). "Syncope in acute aortic dissection: diagnostic, prognostic, and clinical implications".
2011: 1154:, heart block, or a new or old heart attack, it typically does not provide a definite diagnosis for the underlying cause for fainting. Sometimes, a 2727: 3946: 474:. Issues with the heart and blood vessels are the cause in about 10% and typically the most serious while neurally mediated is the most common. 1201: 620:
is pressed. A normal response to carotid sinus massage is reduction in blood pressure and slowing of the heart rate. Especially in people with
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zone (PVZ) as a coordinated neural network participating in the cardioinhibitory Bezold–Jarisch reflex (BJR) regulating fainting and recovery.
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inappropriately. This may occur from either a triggering event such as exposure to blood, pain, strong feelings or a specific activity such as
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and muscle strength characterized by a fast onset, short duration, and spontaneous recovery. It is caused by a decrease in blood flow to the
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view is that some forms of fainting are non-verbal signals that developed in response to increased inter-group aggression during the
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Kenny RA, Bhangu J, King-Kallimanis BL (2013). "Epidemiology of syncope/collapse in younger and older Western patient populations".
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can cause obstructed blood vessels and is the cause of syncope in less than 1% of people who present to the emergency department.
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count may indicate anemia or blood loss. However, this has been useful in only about 5% of people evaluated for fainting. The
2703: 2388: 621: 378:(ECG) are the most effective ways to determine the underlying cause. The ECG is useful to detect an abnormal heart rhythm, 3581: 3402: 1150:
It is estimated that from 20 to 50% of people have an abnormal ECG. However, while an ECG may identify conditions such as
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Freeman R (2011). "Chapter 20: Syncope". In Longo DL, Kasper DL, Jameson JL, Fauci AS, Hauser SL, Loscalzo J (eds.).
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Peeters SY, Hoek AE, Mollink SM, Huff JS (April 2014). "Syncope: risk stratification and clinical decision making".
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Marine JE (2012). "ECG Features that suggest a potentially life-threatening arrhythmia as the cause for syncope".
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Tintinalli, Judith E. Stapczynski, J Stephan. Ma, O John. Yealy, Donald M. Meckler, Garth D. Cline, David (2017).
3649: 3910: 3311: 2406:"Sex differences in symptom presentation in acute myocardial infarction: A systematic review and meta-analysis" 696: 3174: 1648: 1189: 1165: 907: 709: 604:
Syncope may be caused by specific behaviors including coughing, urination, defecation, vomiting, swallowing (
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Strieper MJ (2005-03-01). "Distinguishing Benign Syncope from Life-Threatening Cardiac Causes of Syncope".
1801:"Genome-wide association study identifies locus at chromosome 2q32. 1 associated with syncope and collapse" 1696:"Genome-wide association study identifies locus at chromosome 2q32. 1 associated with syncope and collapse" 1291: 688: 2007: 862:. In a small percentage of cases, the cause of orthostatic hypotensive faints is structural damage to the 3835: 2008:"Swoon at the Sight of Blood? Why the sight of blood might make you faint – and what you can do about it" 1029:. Low blood pressure and a fast heart rate after the event may indicate blood loss or dehydration, while 772: 394:. Low blood pressure and a fast heart rate after the event may indicate blood loss or dehydration, while 906:. While these conditions often impair consciousness they rarely meet the medical definition of syncope. 3814: 1307: 589: 2405: 3830: 3401:
D'Ascenzo F, Biondi-Zoccai G, Reed MJ, Gabayan GZ, Suzuki M, Costantino G, et al. (2013-07-15).
3336: 1241: 1038: 903: 800: 399: 32:"Passing out", "Syncopy", and "Fainting" redirect here. For the completion of a military course, see 1362:
Syncope and presyncope are common in young athletes. In 1990 the American college basketball player
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or "whooping cough". Neurally mediated syncope may also occur when an area in the neck known as the
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minutes. This is often due to an underlying disorder or medication use and is accompanied by other
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Strickberger SA, Benson DW, Biaggioni I, Callans DJ, Cohen MI, Ellenbogen KA, et al. (2006).
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2004 European Society of Cardiology Guidelines on Management (Diagnosis and Treatment) of Syncope
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Dubosh Nicole M., Bellolio M. Fernanda, Rabinstein Alejandro A., Edlow Jonathan A. (2016-03-01).
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Causes range from non-serious to potentially fatal. There are three broad categories of causes:
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Causes range from non-serious to potentially fatal. There are three broad categories of causes:
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Shen WK, Sheldon RS, Benditt DG, Cohen MI, Forman DE, Goldberger ZD, et al. (March 2017).
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Gaynor D, Egan J (2011). "Vasovagal syncope (the common faint): what clinicians need to know".
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Kaufmann H, Bhattacharya K (May 2002). "Diagnosis and treatment of neurally mediated syncope".
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is triggered by an inadequate supply of oxygenated blood in the brain. Common examples include
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Paluso KA (August 2000). "The fainting patient. First and foremost, a meticulous evaluation".
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may be seen following the event in those with pulmonary embolism. More specific tests such as
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episodes of syncope. Rarely, cardiac tumors such as atrial myxomas can also lead to syncope.
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upright. The tilt-table test, if performed, is generally positive. It is relatively uncommon.
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Ruwald MH (August 2013). "Epidemiological studies on syncope – a register based approach".
1237: 775:, acute aortic dissection, pericardial tamponade, pulmonary embolism, aortic stenosis, and 8: 3703: 1221: 1151: 1093: 1050: 989: 787: 727: 633: 411: 327: 3533:"Predictors of Short-Term Outcomes after Syncope: A Systematic Review and Meta-Analysis" 2126: 2101: 2085: 750:
Blockages in major vessels or within the heart can also impede blood flow to the brain.
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Von Bezold (1867). "A. Uber die physiologischen Wirkungen des essigsauren Veratrines".
2174: 2061: 1964: 1825: 1800: 1720: 1695: 1042: 875: 825: 641: 403: 335: 159: 3708: 3506: 3471: 3228: 3211: 2935: 2464: 2210: 2193: 1240:(EEG) is generally not recommended. A bedside ultrasound may be performed to rule out 3900: 3725: 3562: 3510: 3475: 3440: 3432: 3371: 3279: 3233: 3153: 3112: 3063: 3055: 2987: 2920: 2908: 2864: 2846: 2796: 2788: 2709: 2699: 2665: 2624: 2606: 2562: 2503: 2468: 2433: 2425: 2384: 2358: 2350: 2306: 2215: 2178: 2166: 2150: 2131: 2113: 2066: 1956: 1952: 1918: 1910: 1830: 1781: 1725: 1595: 1561: 1356: 1253: 1104: 1074: 1066: 1030: 1010: 807: 645: 525: 514: 435: 427: 395: 375: 339: 226: 220: 143: 1649:"Syncope Information Page | National Institute of Neurological Disorders and Stroke" 651: 3765: 3552: 3544: 3502: 3467: 3422: 3414: 3269: 3261: 3223: 3143: 3102: 3094: 3045: 3037: 2979: 2900: 2854: 2836: 2780: 2750: 2677: 2655: 2614: 2596: 2552: 2542: 2515: 2495: 2460: 2417: 2296: 2205: 2158: 2121: 2105: 2056: 2048: 1968: 1948: 1820: 1812: 1771: 1763: 1715: 1707: 1217: 1140: 1128: 1022: 1018: 981: 914: 731: 719: 665: 387: 383: 95: 3287: 2383:(Textbook) (18th ed.). New York: The McGraw-Hill Companies. pp. 171–77. 2084:
Lovelace JW, Ma J, Yadav S, Chhabria K, Shen H, Pang Z, et al. (2023-11-09).
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expression of ZNF804A, making this gene the strongest driver of the association.
358:. Neurally mediated syncope may also occur when an area in the neck known as the 288: 272: 3771: 3363: 2531:"Operating theatre related syncope in medical students: a cross sectional study" 2052: 1315:
risk scores even combined with cardiac biomarkers at predicting adverse events.
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Chen-Scarabelli C, Scarabelli TM: Neurocardiogenic syncope. BMJ 2004;329:336–41
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among others. Neurally mediated syncope occurs when blood vessels expand and
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The respiratory system may compensate for dropping oxygen levels through
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is that fainting at the sight of blood might have evolved as a form of
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Tintinalli's Emergency Medicine : A Comprehensive Study Guide, 9e
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or diabetes) or in neurological diseases (e.g., Parkinson's disease).
3877: 3760: 3400: 3026: 1382: 1287: 1078: 855: 613: 494: 439: 368: 347: 296: 241: 148: 3305: 303:. It is recommended that presyncope be treated the same as syncope. 67: 2775:. Seizures, Syncope, and Sudden Death: Recognizing Cardiac Causes. 2250:"Cardiac manifestations and sequelae of gastrointestinal disorders" 1124: 1026: 918: 895: 502: 498: 391: 355: 351: 284: 3307:
Transient loss of consciousness in adults and young people (CG109)
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may present with sudden loss of consciousness similar to syncope.
910:
transient ischemic attacks may produce true syncope as a symptom.
489:
or neurally mediated syncope occurs when blood vessels expand and
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There are other conditions which may cause or resemble syncope.
730:. The degree of QT prolongation determines the risk of syncope. 3855: 3688: 3629: 1261: 1058: 899: 419: 3865: 3173: 2247: 1278: 734:
also commonly presents with syncope secondary to arrhythmia.
669: 609: 455: 307: 276: 213: 3845: 3492: 3081:
Moya A, Sutton R, Ammirati F, et al. (November 2009).
2936:"Review of Important ECG Findings in Patients with Syncope" 1355:
Fainting in women was a commonplace trope or stereotype in
1025:. Heart related causes also often have little history of a 390:. Heart related causes also often have little history of a 119: 113: 107: 2282: 1753: 2151:"What causes fainting? Scientists finally have an answer" 1359:
and in contemporary and modern depictions of the period.
1225: 371:. There also seems to be a genetic component to syncope. 104: 3457: 969:
shortness of breath, or difficulty breathing, wheezing"
3129: 2283:
Dicpinigaitis PV, Lim L, Farmakidis C (February 2014).
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Journal of the American Academy of Physician Assistants
1107:(ECG) finds that should be looked for include signs of 1684:
2021;100(10):978-982. doi:10.1097/PHM.0000000000001690
1551: 640:
or heart muscle, or blockages of blood vessels from a
334:
or heart muscle and blockages of blood vessels from a
3179:"Five Things Physicians and Patients Should Question" 2529:
Jamjoom AA, Nikkar-Esfahani A, Fitzgerald JE (2009).
2248:
Manisty C, Hughes-Roberts Y, Kaddoura S (July 2009).
1408:) 'cutting up', 'sudden loss of strength', from σύν ( 762: 128: 110: 101: 3666: 2450: 1938: 925: 664:
The most common cause of cardiac syncope is cardiac
116: 2485: 2403: 1244:in people with concerning history or presentation. 98: 3080: 889: 539:Vasovagal syncope can be considered in two forms: 1983:"Why do Some People Faint at the Sight of Blood?" 27:Transient loss of consciousness and postural tone 3933: 3361: 995:Low blood sugar can be a rare cause of syncope. 1798: 1693: 624:this response can cause syncope or presyncope. 3813: 3530: 2404:Coventry LL, Finn J, Bremner AP (2011-11-01). 2374: 2372: 3799: 3640:2017 American College of Cardiology Guideline 3136:Journal of the American College of Cardiology 2822: 2582: 2198:Journal of the American College of Cardiology 1009:A medical history, physical examination, and 973:Lactose intolerance § Signs and symptoms 745: 374:A medical history, physical examination, and 61:Fainting, blacking out, passing out, swooning 2726:: CS1 maint: multiple names: authors list ( 2041:Prog. Neuropsychopharmacol. Biol. Psychiatry 1195:A short PR in Wolff–Parkinson–White syndrome 481: 3337:"American Epilepsy Society Choosing Wisely" 2522: 2369: 1749: 1747: 1745: 1743: 1741: 1739: 1252:Other diseases which mimic syncope include 592:vagal sensory neurons (NPY2R VSNs) and the 3806: 3792: 3169: 3167: 2963: 2961: 2959: 2740: 2488:The American Journal of Emergency Medicine 2381:Harrison's Principles of Internal Medicine 2232: 1643: 1641: 1639: 1637: 1635: 1633: 1631: 1629: 1137:arrhythmogenic right ventricular dysplasia 838:Orthostatic (postural) hypotensive syncope 66: 3556: 3426: 3362:Mechanic OJ, Grossman SA (18 July 2022). 3273: 3227: 3147: 3106: 3049: 2858: 2840: 2659: 2618: 2600: 2556: 2546: 2300: 2209: 2125: 2060: 2031: 1824: 1775: 1719: 1627: 1625: 1623: 1621: 1619: 1617: 1615: 1613: 1611: 1609: 1547: 1545: 1543: 1541: 1539: 1537: 1535: 1533: 1531: 1529: 1527: 1525: 1523: 1521: 1519: 1517: 1515: 1513: 1511: 1509: 1507: 1505: 1503: 1501: 1499: 1497: 1495: 1493: 1491: 1489: 1487: 1485: 1483: 1481: 1479: 1477: 1475: 1473: 1471: 1469: 1467: 1465: 1463: 1461: 1247: 1228:is not generally needed. Likewise, using 821:, may cause bradycardia induced syncope. 285:symptoms before the loss of consciousness 3619:) is being considered for deletion. See 3329: 2770: 1736: 1581: 1579: 1577: 1575: 1459: 1457: 1455: 1453: 1451: 1449: 1447: 1445: 1443: 1441: 1328:one event at some point in their lives. 1298:depending on the precise cardiac cause. 695:). SVT does not cause syncope except in 650: 3531:Gibson T, Weiss R, Sun B (2018-04-30). 3364:"Syncope And Related Paroxysmal Spells" 3164: 3123: 2956: 2933: 2378: 1412:, "together, thoroughly") and κόπτειν ( 1296:implantable cardioverter-defibrillators 1133:hypertrophic obstructive cardiomyopathy 782: 225:Medical history, physical examination, 36:. For the film production company, see 14: 3947:Symptoms and signs of mental disorders 3934: 3195:from the original on September 1, 2013 2967: 2766: 2764: 2578: 2576: 2148: 1934: 1932: 1900: 1606: 1585: 1340: 1004: 659: 599: 548:, if performed, is generally negative. 3787: 3579: 3537:Western Journal of Emergency Medicine 3526: 3524: 3396: 3394: 3392: 3022: 3020: 3018: 3016: 3014: 3012: 3010: 2943:American Journal of Clinical Medicine 2825:"Syncope in the Emergency Department" 2818: 2816: 2814: 2812: 2810: 2689: 2687: 2585:"Syncope in the Emergency Department" 2336: 2332: 2330: 2328: 2326: 2324: 2322: 2320: 1896: 1894: 1892: 1890: 1888: 1886: 1884: 1882: 1880: 1878: 1876: 1874: 1872: 1870: 1868: 1866: 1864: 1572: 1438: 1311:not validated by subsequent studies. 1096:, and turning blue during the event. 1017:and other electrical issues, such as 622:hypersensitive carotid sinus syndrome 382:and other electrical issues, such as 3662:. U.S. National Library of Medicine. 3314:from the original on 29 October 2013 2829:Frontiers in Cardiovascular Medicine 2589:Frontiers in Cardiovascular Medicine 2191: 1862: 1860: 1858: 1856: 1854: 1852: 1850: 1848: 1846: 1844: 1099: 675:Two major groups of arrhythmias are 632:Heart-related causes may include an 508: 3407:International Journal of Cardiology 3030:International Journal of Cardiology 2761: 2573: 1929: 1756:Progress in Cardiovascular Diseases 1015:poor blood flow to the heart muscle 722:can cause syncope when it sets off 584:as well as the gender differences. 578:blood-injection-injury type phobias 380:poor blood flow to the heart muscle 24: 3521: 3389: 3007: 2984:10.1016/j.jelectrocard.2013.07.008 2807: 2684: 2317: 2235:Untersch. Physiolog. Lab. Würzburg 1049:may be useful in uncertain cases. 763:Structural cardiopulmonary disease 410:may be useful in uncertain cases. 25: 3958: 3623:to help reach a consensus. › 3602: 3507:10.1016/j.annemergmed.2007.12.007 3472:10.1016/j.annemergmed.2005.11.019 3229:10.1161/CIRCULATIONAHA.105.170274 3191:, American Academy of Neurology, 2264:from the original on 11 June 2013 1909:(8): 40–42, 48–49, 53–54 passim. 1841: 926:Vertebro-basilar arterial disease 831: 708:, which is rapidly fatal without 1953:10.1097/00127893-200205000-00004 1200: 1188: 1176: 1164: 866:due to systemic diseases (e.g., 850:This may be due to medications, 94: 3573: 3486: 3451: 3355: 3074: 2998: 2927: 2884: 2875: 2773:Seminars in Pediatric Neurology 2734: 2635: 2479: 2444: 2397: 2276: 2241: 2226: 2185: 2142: 2077: 2025: 2014:from the original on 2015-09-06 2000: 1989:from the original on 2016-08-01 1975: 1318: 980:Some psychological conditions ( 934: 890:Central nervous system ischemia 683:. Bradycardia can be caused by 612:, such as that associated with 3650:The San Francisco syncope rule 3586:American College of Cardiology 2823:Sandhu RK, Sheldon RS (2019). 2583:Sandhu RK, Sheldon RS (2019). 1792: 1687: 1674: 1665: 1232:on the premise of identifying 697:Wolff-Parkinson-White syndrome 528:is triggered via the afferent 13: 1: 3608: 3175:American Academy of Neurology 2698:. McGraw-Hill Education LLC. 2465:10.1016/S0002-9343(02)01254-8 2211:10.1016/S0735-1097(83)80014-X 1431: 1393:The term is derived from the 1301: 1267: 817:Various medications, such as 710:cardiopulmonary resuscitation 3549:10.5811/westjem.2018.2.37100 3419:10.1016/j.ijcard.2011.11.083 3042:10.1016/j.ijcard.2011.11.083 2971:Journal of Electrocardiology 2661:10.1161/STROKEAHA.115.011386 2422:10.1016/j.hrtlng.2011.05.001 1388: 1331: 814:can also result in syncope. 689:supraventricular tachycardia 687:. Tachycardias include SVT ( 7: 3836:Persistent vegetative state 2053:10.1016/j.pnpbp.2006.01.008 1682:Am. J. Phys. Med. Rehabil.. 1554:Emergency Medicine Practice 1419: 970: 773:hypertrophic cardiomyopathy 246:Depends on underlying cause 10: 3963: 3815:Disorders of consciousness 3149:10.1016/j.jacc.2017.03.003 2785:10.1016/j.spen.2005.01.001 2500:10.1016/j.ajem.2017.09.015 2302:10.1016/j.rmed.2013.10.020 2163:10.1038/d41586-023-03450-3 2110:10.1038/s41586-023-06680-7 1799:Hadji-Turdeghal K (2019). 1768:10.1016/j.pcad.2012.11.006 1694:Hadji-Turdeghal K (2019). 1377:primarily reported in the 1344: 1308:San Francisco syncope rule 1212: 1207:Type 2 Brugada ECG pattern 1039:implantable loop recorders 904:transient ischemic attacks 854:, significant bleeding or 810:(a tear in the aorta) and 804:(most commonly the left). 746:Obstructive cardiac lesion 627: 590:neuropeptide Y receptor Y2 512: 400:implantable loop recorders 367:, significant bleeding or 212:Decrease in blood flow to 31: 3909: 3886: 3831:Minimally conscious state 3821: 3740: 3670: 3370:. StatPearls Publishing. 2343:American Family Physician 1242:abdominal aortic aneurysm 952:are of an unknown cause. 896:central ischemic response 801:Subclavian steal syndrome 482:Neurally mediated syncope 449: 250: 240: 236:Based on underlying cause 232: 219: 208: 197: 189: 181: 171: 158: 142: 86: 74: 65: 57: 52: 3621:templates for discussion 3266:10.1093/eurheartj/ehp298 3099:10.1093/eurheartj/ehp298 2192:Mark AL (January 1983). 1290:syncope and may involve 986:somatic symptom disorder 864:autonomic nervous system 706:ventricular fibrillation 655:Syncope from bradycardia 544:invariably upright. The 3186:: an initiative of the 2842:10.3389/fcvm.2019.00180 2602:10.3389/fcvm.2019.00180 2339:"Evaluation of Syncope" 2149:Naddaf M (2023-11-01). 2032:Bracha HS (July 2006). 1805:Cardiovascular Research 1700:Cardiovascular Research 1560:(4): 1–22, quiz 22–23. 1230:carotid ultrasonography 1117:atrioventricular blocks 1079:monitoring of the heart 1031:low blood oxygen levels 724:ventricular tachycardia 701:Ventricular tachycardia 693:ventricular tachycardia 570:evolutionary psychology 558:evolutionary psychology 472:orthostatic hypotension 440:monitoring of the heart 396:low blood oxygen levels 324:orthostatic hypotension 203:orthostatic hypotension 75:A 1744 oil painting by 3582:"The Syncopal Athlete" 3580:Madan S (2016-04-29). 3341:www.choosingwisely.org 3254:European Heart Journal 3004:Grubb (2001) pp. 83–84 2905:10.1001/jama.2019.8001 2743:The Irish Psychologist 2548:10.1186/1472-6920-9-14 2337:Gauer R (2011-09-15). 1588:Danish Medical Journal 1416:, "strike, cut off"). 1379:southern United States 1375:culture-bound syndrome 1248:Differential diagnosis 1234:carotid artery disease 777:pulmonary hypertension 740:atrioventricular block 656: 283:. There are sometimes 42:Faint (disambiguation) 34:passing out (military) 3310:, NICE, August 2010, 1135:(HOCM), and signs of 1047:carotid sinus massage 962:orthostatic syncope. 950:hair-grooming syncope 794:Adams-Stokes syndrome 654: 634:abnormal heart rhythm 408:carotid sinus massage 328:abnormal heart rhythm 273:loss of consciousness 254:~5 per 1,000 per year 165:Loss of consciousness 2289:Respiratory Medicine 1238:electroencephalogram 884:hypoadrenergic signs 783:Other cardiac causes 636:, problems with the 491:heart rate decreases 344:heart rate decreases 330:, problems with the 263:, commonly known as 40:For other uses, see 2102:2023Natur.623..387L 1341:Society and culture 1260:, certain types of 1222:computed tomography 1152:atrial fibrillation 1094:atrial fibrillation 1051:Computed tomography 1005:Diagnostic approach 990:conversion disorder 966:Lactose intolerance 788:Sick sinus syndrome 728:torsades de pointes 660:Cardiac arrhythmias 600:Situational syncope 412:Computed tomography 167:and muscle strength 3921:Locked-in syndrome 3741:External resources 3626:Syncope (medicine) 2934:Toscano J (2012). 2881:Grubb (2001) p. 83 1817:10.1093/cvr/cvz106 1712:10.1093/cvr/cvz106 1147:in lead V1 to V3. 1043:tilt table testing 917:, though a sudden 826:pulmonary embolism 657: 642:pulmonary embolism 404:tilt table testing 336:pulmonary embolism 281:low blood pressure 3929: 3928: 3901:Vasovagal episode 3781: 3780: 3177:(February 2013), 2705:978-1-260-01993-3 2390:978-0-07-174889-6 2096:(7986): 387–396. 1653:www.ninds.nih.gov 1357:Victorian England 1105:Electrocardiogram 1100:Electrocardiogram 1075:drug intoxication 1011:electrocardiogram 945:Akinetic seizures 844:stretch receptors 808:Aortic dissection 646:aortic dissection 515:Vasovagal syncope 509:Vasovagal syncope 436:drug intoxication 376:electrocardiogram 340:aortic dissection 279:, typically from 258: 257: 227:electrocardiogram 221:Diagnostic method 201:Cardiac, reflex, 47:Medical condition 16:(Redirected from 3954: 3808: 3801: 3794: 3785: 3784: 3668: 3667: 3663: 3596: 3595: 3593: 3592: 3577: 3571: 3570: 3560: 3528: 3519: 3518: 3490: 3484: 3483: 3455: 3449: 3448: 3430: 3398: 3387: 3386: 3384: 3382: 3359: 3353: 3352: 3350: 3348: 3343:. 14 August 2018 3333: 3327: 3322: 3321: 3319: 3301: 3299: 3298: 3292: 3286:. 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1180: 1171:ECG showing HOCM 1168: 1141:T wave inversion 1129:Brugada syndrome 1067:low blood oxygen 1023:Brugada syndrome 1019:long QT syndrome 976: 915:hyperventilation 732:Brugada syndrome 720:Long QT syndrome 466:, also known as 428:low blood oxygen 388:Brugada syndrome 384:long QT syndrome 318:, also known as 131: 126: 125: 122: 121: 118: 115: 112: 109: 106: 103: 100: 70: 50: 49: 21: 3962: 3961: 3957: 3956: 3955: 3953: 3952: 3951: 3932: 3931: 3930: 3925: 3912: 3905: 3882: 3851:Brainstem death 3823:Unconsciousness 3817: 3812: 3782: 3777: 3776: 3736: 3735: 3679: 3654: 3645:Tilt table test 3624: 3605: 3600: 3599: 3590: 3588: 3578: 3574: 3529: 3522: 3491: 3487: 3456: 3452: 3399: 3390: 3380: 3378: 3360: 3356: 3346: 3344: 3335: 3334: 3330: 3317: 3315: 3304: 3296: 3294: 3290: 3260:(21): 2631–71. 3249: 3204:, which cites: 3198: 3196: 3188:ABIM Foundation 3184:Choosing Wisely 3172: 3165: 3142:(5): e39–e110. 3128: 3124: 3093:(21): 2631–71. 3079: 3075: 3025: 3008: 3003: 2999: 2966: 2957: 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289:lightheadedness 138: 129: 97: 93: 48: 45: 28: 23: 22: 15: 12: 11: 5: 3960: 3950: 3949: 3944: 3927: 3926: 3924: 3923: 3917: 3915: 3907: 3906: 3904: 3903: 3898: 3892: 3890: 3884: 3883: 3881: 3880: 3875: 3874: 3873: 3868: 3863: 3853: 3848: 3843: 3838: 3833: 3827: 3825: 3819: 3818: 3811: 3810: 3803: 3796: 3788: 3779: 3778: 3775: 3774: 3757: 3745: 3744: 3742: 3738: 3737: 3734: 3733: 3722: 3711: 3696: 3680: 3675: 3674: 3672: 3671:Classification 3665: 3664: 3652: 3647: 3642: 3637: 3632: 3604: 3603:External links 3601: 3598: 3597: 3572: 3520: 3485: 3450: 3388: 3354: 3328: 3326: 3325: 3324: 3323: 3302: 3242: 3163: 3122: 3073: 3006: 2997: 2955: 2926: 2883: 2874: 2806: 2760: 2733: 2704: 2683: 2634: 2572: 2521: 2478: 2443: 2396: 2389: 2368: 2316: 2275: 2240: 2225: 2184: 2141: 2076: 2024: 1999: 1974: 1928: 1840: 1791: 1735: 1686: 1673: 1664: 1605: 1571: 1436: 1435: 1433: 1430: 1429: 1428: 1421: 1418: 1390: 1387: 1367:on game days. 1351:Fainting couch 1342: 1339: 1333: 1330: 1320: 1317: 1303: 1300: 1269: 1266: 1249: 1246: 1214: 1211: 1210: 1209: 1206: 1199: 1197: 1194: 1187: 1185: 1182: 1175: 1173: 1170: 1163: 1156:Holter monitor 1109:heart ischemia 1101: 1098: 1006: 1003: 936: 933: 927: 924: 891: 888: 833: 832:Blood pressure 830: 812:cardiomyopathy 784: 781: 764: 761: 747: 744: 714:defibrillation 661: 658: 629: 626: 601: 598: 554: 553: 549: 513:Main article: 510: 507: 487:Reflex syncope 483: 480: 470:mediated; and 451: 448: 322:mediated; and 256: 255: 252: 248: 247: 244: 238: 237: 234: 230: 229: 223: 217: 216: 210: 206: 205: 199: 195: 194: 193:Short duration 191: 187: 186: 183: 179: 178: 175: 169: 168: 162: 156: 155: 146: 140: 139: 137: 136: 90: 88: 84: 83: 72: 71: 63: 62: 59: 55: 54: 46: 26: 9: 6: 4: 3: 2: 3959: 3948: 3945: 3943: 3942:Consciousness 3940: 3939: 3937: 3922: 3919: 3918: 3916: 3914: 3913:consciousness 3911:Alteration of 3908: 3902: 3899: 3897: 3894: 3893: 3891: 3889: 3885: 3879: 3876: 3872: 3869: 3867: 3864: 3862: 3859: 3858: 3857: 3854: 3852: 3849: 3847: 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Index

Syncopy
passing out (military)
Syncopy Inc.
Faint (disambiguation)

Pietro Longhi
/ˈsɪŋkəpi/
SING-kə-pee
Specialty
Neurology
cardiology
Symptoms
Loss of consciousness
Complications
orthostatic hypotension
brain
Diagnostic method
electrocardiogram
Prognosis
loss of consciousness
brain
low blood pressure
symptoms before the loss of consciousness
lightheadedness
sweating
pale skin
presyncope
heart
blood vessel
reflex

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