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Flunitrazepam

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667: 644: 51: 1472: 42: 1187:. All benzodiazepines work by enhancing the effect of GABA receptors, which, when active, allow chloride ions to enter the neuron. Negative ions such as chloride inhibit the ability of neurons to fire. It is this stimulation of GABA receptors which is responsible for the depressant effects of benzodiazepines. Flunitrazepam shows high affinity for the α-5 subunit of the GABA-A receptor, which causes some of its unique side effects, such as amnesia. 1364:
nitrazepam occurred in significantly higher concentrations compared to natural deaths. Of the 159 deaths where any benzodiazepines were found, 4 deaths were caused by benzodiazepines alone (in the other 155 cases, benzodiazepines were combined with something else). One conclusion of the study was that flunitrazepam and nitrazepam might be more toxic than other benzodiazepines available in the Swedish market.
1289: 1281: 853: 1316:(alprazolam, clonazepam, lorazepam, clobazam, and bromazepam) were negligible. When calculated in relation to utilization, the narcotic analgesics codeine, pentazocine, and ketobemidone were at the top of the list for the highest number of overall prescription forgeries, suggesting a higher abuse potential of these drugs. In neighboring 1154:
receiving the drug therapeutically as a nighttime hypnotic, 10–50 μg/L in those arrested for impaired driving and 100–1000 μg/L in victims of acute fatal overdosage. Urine is often the preferred specimen for routine substance use monitoring purposes. The presence of 7-aminoflunitrazepam, a pharmacologically active metabolite and
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In the United Kingdom, the use of flunitrazepam and other "date rape" drugs have also been connected to stealing from sedated victims. An activist quoted by a British newspaper estimated that up to 2,000 individuals are robbed each year after being spiked with powerful sedatives, making drug-assisted
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of 18–26 hours, which means that flunitrazepam's effects after nighttime administration persist throughout the next day. This is due to the production of active metabolites. These metabolites further increase the duration of drug action compared to benzodiazepines that produce nonactive metabolites.
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As of 2016, blood tests can identify flunitrazepam at concentrations of as low as 4 nanograms per millilitre; the elimination half life of the drug is 4–12 hours. For urine samples, metabolites can be identified for 60 hours to 28 days, depending on the dose and analytical method used. Hair and
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In studies in Sweden, flunitrazepam was the second most common drug used in suicides, being found in about 16% of cases. In a retrospective Swedish study of 1,587 deaths, in 159 cases benzodiazepines were found. In suicides when benzodiazepines were implicated, the benzodiazepines flunitrazepam and
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and recreation, in 1998 Roche modified the formulation to give lower doses, make it less soluble, and add a blue dye for easier detection in drinks. It was never marketed in the United States, and by 2016 had been withdrawn from the markets in Spain, France, Norway, Germany, and the United Kingdom.
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Flunitrazepam can be measured in blood or plasma to confirm a diagnosis of poisoning in hospitalized patients, provide evidence in an impaired driving arrest, or assist in a medicolegal death investigation. Blood or plasma flunitrazepam concentrations are usually in a range of 5–20 μg/L in persons
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is probably the most important adverse effect. This side-effect is not unique to flunitrazepam but also occurs with other hypnotic drugs. Flunitrazepam seems to have a particularly high risk of road traffic accidents compared to other hypnotic drugs. Extreme caution should be exercised by drivers
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accounted for 13% of forged prescriptions, and accounted for 44% of forgeries specifically for benzodiazepines while flunitrazepam, diazepam, and oxazepam accounted for the majority of the rest of benzodiazepine forgeries. Prescription forgeries for other benzodiazepines marketed in Sweden
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in sufficient doses; individuals are unable to remember certain events that they experienced while under the influence of the drug, which complicates investigations. This effect could be particularly dangerous if flunitrazepam is used to aid in the commission of
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Flunitrazepam is marketed under many brand names in the countries where it is legal. It also has many street names, including "roofie" and "ruffie". It is also known as Circles, Forget Me Pill, La Rocha, Lunch Money Drug, Mexican Valium, Pingus, R2, and Roach 2.
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provide for punishment for the importation and distribution of up to 20 years in prison and a fine; possession is punishable by three years and a fine. Travelers travelling into the United States are limited to a 30-day supply. The drug must be declared to
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While use of flunitrazepam in sexual assault has been prominent in the media, as of 2015 it appears to be fairly rare, and use of alcohol and other benzodiazepine drugs in date rape appears to be a larger but underreported problem.
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Flunitrazepam is a drug that is frequently involved in drug intoxication, including overdose. Overdose of flunitrazepam may result in excessive sedation, or impairment of balance or speech. This may progress in severe overdoses to
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Gustavsen I, Bramness JG, Skurtveit S, Engeland A, Neutel I, Mørland J (December 2008). "Road traffic accident risk related to prescriptions of the hypnotics zopiclone, zolpidem, flunitrazepam and nitrazepam".
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degradation product, is useful for confirmation of flunitrazepam ingestion. In postmortem specimens, the parent drug may have been entirely degraded over time to 7-aminoflunitrazepam. Other metabolites include
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In Sweden, flunitrazepam is a List II drug (substances with medicinal uses) under the Narcotics Control Act (1968). It was previously available from Mylan, but has been removed from the market in January
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In Norway, on January 1, 2003, flunitrazepam was moved up one level in the schedule of controlled drugs and, on August 1, 2004, the manufacturer Roche removed Rohypnol from the market there altogether.
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Jonasson B, Jonasson U, Saldeen T (January 2000). "Among fatal poisonings dextropropoxyphene predominates in younger people, antidepressants in the middle aged and sedatives in the elderly".
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Flunitrazepam and other sedative hypnotic drugs are detected frequently in cases of people suspected of driving under the influence of drugs. Other benzodiazepines and nonbenzodiazepines (
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Freuchen I, Ostergaard J, Kühl JB, Mikkelsen BO (1976). "Reduction of psychotomimetic side effects of Ketalar (ketamine) by Rohypnol (flunitrazepam). A randomized, double-blind trial".
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Jones AW, Holmgren A, Kugelberg FC (April 2007). "Concentrations of scheduled prescription drugs in blood of impaired drivers: considerations for interpreting the results".
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Jones AW, Holmgren A, Kugelberg FC (April 2007). "Concentrations of scheduled prescription drugs in blood of impaired drivers: considerations for interpreting the results".
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Neuropathology of drug addictions and substance misuse. Volume 2, Stimulants, club and dissociative drugs, hallucinogens, steroids, inhalants, and international aspects
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Benzodiazepines require special precaution if used in the elderly, during pregnancy, in children, in alcohol- or drug-dependent individuals, and in individuals with
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Authier N, Balayssac D, Sautereau M, Zangarelli A, Courty P, Somogyi AA, et al. (November 2009). "Benzodiazepine dependence: focus on withdrawal syndrome".
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Statement on "Date Rape" Drugs by Associate Director for Domestic and International Drug Control, Office of Health Affairs, FDA, before Congress. Mar. 11, 1999.
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Kanto JH (May 1982). "Use of benzodiazepines during pregnancy, labour and lactation, with particular reference to pharmacokinetic considerations".
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Kales A, Scharf MB, Kales JD, Soldatos CR (April 1979). "Rebound insomnia. A potential hazard following withdrawal of certain benzodiazepines".
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It was patented in 1962 and came into medical use in 1974. Flunitrazepam, nicknamed "roofies" or "floonies", is widely known for its use as a
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with significant uptake of the drug. Use of benzodiazepines including flunitrazepam in late pregnancy, especially high doses, may result in
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In South Africa, Rohypnol is classified as a Schedule 6 drug. It is available by prescription only, and restricted to 1 mg doses.
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Cano JP, Soliva M, Hartmann D, Ziegler WH, Amrein R (1977). "Bioavailability from various galenic formulations of flunitrazepam".
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saliva can also be analyzed; hair is useful when a long time has transpired since ingestion, and saliva for workplace drug tests.
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Mets MA, Volkerts ER, Olivier B, Verster JC (August 2010). "Effect of hypnotic drugs on body balance and standing steadiness".
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Bramness JG, Skurtveit S, Mørland J (June 2006). "Flunitrazepam: psychomotor impairment, agitation and paradoxical reactions".
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under the trade name Rohypnol and is indicated for the treatment of insomnia as well as used for preanesthetic medication.
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Adverse effects of flunitrazepam include dependency, both physical and psychological; reduced sleep quality resulting in
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Mattila MA, Larni HM (November 1980). "Flunitrazepam: a review of its pharmacological properties and therapeutic use".
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In Australia, as of 2013 the drug was authorized for prescribing for severe cases of insomnia but was restricted as a
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Bergman U, Dahl-Puustinen ML (November 1989). "Use of prescription forgeries in a drug abuse surveillance network".
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The use of flunitrazepam in combination with alcoholic beverages synergizes the adverse effects, and can lead to
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or coma and possibly death. The risk of overdose is increased if flunitrazepam is taken in combination with
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Drummer OH, Syrjanen ML, Cordner SM (September 1993). "Deaths involving the benzodiazepine flunitrazepam".
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InChI=1S/C16H12FN3O3/c1-19-14-7-6-10(20(22)23)8-12(14)16(18-9-15(19)21)11-4-2-3-5-13(11)17/h2-8H,9H2,1H3
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Carlsten A, Waern M, Holmgren P, Allebeck P (2003). "The role of benzodiazepines in elderly suicides".
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In the United Kingdom, flunitrazepam is not licensed for medical use and is a controlled drug under
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Alapi EM, Fischer J (2006). "Table of Selected Analogue Classes". In Fische J, Ganellin CR (eds.).
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Robertson MD, Drummer OH (January 1998). "Stability of nitrobenzodiazepines in postmortem blood".
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Schwartz RH, Milteer R, LeBeau MA (June 2000). "Drug-facilitated sexual assault ('date rape')".
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Flunitrazepam is lipophilic and is metabolised by the liver via oxidative pathways. The enzyme
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increases these impairments. Partial, but incomplete tolerance develops to these impairments.
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Vermeeren A (2004). "Residual effects of hypnotics: epidemiology and clinical implications".
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upon arrival. If a valid prescription cannot be produced, the drug may be subject to Customs
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Bramness JG, Skurtveit S, Furu K, Engeland A, Sakshaug S, Rønning M (February 2006). "".
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In Ireland, flunitrazepam is a Schedule 3 controlled substance with strict restrictions.
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Hesse LM, Venkatakrishnan K, von Moltke LL, Shader RI, Greenblatt DJ (February 2001).
2362: 1021:—the inability to create memories while under the influence. It can be described as a 9341: 9221: 9023: 8722: 8493: 8436: 8377: 8145: 7717: 6812: 6589: 6584: 6132: 5280: 5238: 5071: 4746: 4741: 4279: 3600: 3249: 3059: 2971: 2967: 2936: 2909: 2866: 2801: 2737: 2703: 2664: 2629: 2598: 2557: 2486: 2443: 2406: 2366: 2331: 2256: 2210: 2175: 2132: 2128: 2086: 2082: 2051: 2016: 1946: 1903: 1860: 1856: 1796: 1737: 1733: 1700: 1572: 1252: 1030: 1013:
Flunitrazepam impairs cognitive functions. This may appear as lack of concentration,
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In countries where this drug is used, it is used for treatment of severe cases of
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Ericsson HR, Holmgren P, Jakobsson SW, Lafolie P, De Rees B (November 1993). "".
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It has also been administered as a concurrent dose for patients that are taking
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Robertson MD, Drummer OH (May 1995). "Postmortem drug metabolism by bacteria".
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drugs; falls and hip fractures were frequently reported. The combination with
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reports that benzodiazepines accounted for 52% of prescription forgeries in
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and rapidly penetrate membranes and, therefore, rapidly cross over into the
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Jonasson B, Saldeen T (March 2002). "Citalopram in fatal poisoning cases".
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The main pharmacological effects of flunitrazepam are the enhancement of
968: 8717: 3149:"Authorisation to Supply or Prescribe Drugs of Addiction: Flunitrazepam" 3002: 2699: 2561: 1232:. Other nitro-benzodiazepines include nitrazepam (the parent compound), 512: 9846: 9821: 9801: 9796: 9771: 9676: 9664: 9636: 9554: 9528: 9524: 9510: 9500: 9471: 9459: 9455: 9426: 9421: 9376: 9315: 9297: 9282: 9201: 9185: 9181: 9163: 9147: 9099: 9087: 9073: 9010: 8933: 8891: 8685: 8637: 8632: 8550: 8545: 8451: 8422: 8418: 8327: 8292: 8237: 8227: 8187: 8120: 7948: 7913: 7878: 7873: 7827: 7817: 7746: 7707: 7667: 7652: 7632: 7622: 7561: 7556: 7546: 7513: 7495: 7391: 7338: 7303: 7250: 7240: 7210: 7205: 7142: 7117: 7072: 7047: 7027: 7007: 7002: 6992: 6972: 6927: 6917: 6902: 6862: 6857: 6827: 6782: 6777: 6757: 6747: 6727: 6722: 6712: 6672: 6667: 6662: 6657: 6652: 6642: 6637: 6632: 6604: 6459: 6374: 6369: 6255: 6245: 6220: 6101: 6074: 6064: 5985: 5965: 5938: 5873: 5849: 5844: 5727: 5722: 5712: 5702: 5663: 5658: 5569: 5511: 5496: 5307: 5213: 5109: 5089: 5056: 5046: 5036: 5026: 4993: 4975: 4960: 4907: 4902: 4864: 4859: 4834: 4819: 4789: 4784: 4774: 4756: 4428: 4411: 4335: 4304: 4269: 4259: 4220: 4187: 4182: 4161: 4121: 4106: 4096: 4081: 4076: 4050: 4040: 4035: 4005: 4000: 3994: 3989: 3984: 3961: 3951: 3920: 3905: 3884: 3857: 3800: 3765: 3750: 3740: 3712: 3625: 3610: 3570: 3559: 3539: 3524: 3493: 3488: 2797: 2251: 1907: 1532: 1454:
In Japan, flunitrazepam is marketed by Japanese pharmaceutical company
1443: 1324: 1312: 1237: 1229: 1138: 884: 834: 715: 523: 363: 188: 2905: 2660: 2482: 9874: 9831: 9816: 9811: 9682: 9626: 9622: 9515: 9446: 9386: 9326: 9321: 9287: 9197: 9193: 9134: 9124: 9103: 9049: 8953: 8920: 8675: 8627: 8622: 8607: 8565: 8560: 8518: 8513: 8508: 8466: 8362: 8347: 8287: 8272: 8257: 8077: 7988: 7943: 7908: 7898: 7868: 7863: 7848: 7822: 7784: 7779: 7756: 7751: 7736: 7642: 7637: 7518: 7396: 7386: 7378: 7313: 7290: 7270: 7265: 7235: 7220: 7190: 7172: 7162: 7157: 7152: 7147: 7127: 7112: 7107: 7097: 7092: 7087: 7057: 7032: 6982: 6967: 6962: 6947: 6932: 6912: 6907: 6897: 6887: 6882: 6877: 6797: 6792: 6767: 6697: 6677: 6647: 6569: 6504: 6434: 6424: 6389: 6286: 6190: 6111: 5905: 5795: 5762: 5697: 5609: 5574: 5526: 5369: 5322: 5129: 5114: 5104: 5094: 5003: 4965: 4955: 4947: 4932: 4889: 4879: 4874: 4844: 4799: 4736: 4671: 4484: 4406: 4401: 4396: 4390: 4374: 4316: 4230: 4197: 4156: 4151: 4146: 4141: 4126: 4116: 4111: 4060: 4045: 4010: 3966: 3956: 3941: 3889: 3868: 3862: 3852: 3847: 3842: 3837: 3832: 3827: 3822: 3811: 3805: 3770: 3725: 3697: 3686: 3676: 3671: 3660: 3655: 3650: 3645: 3640: 3585: 3549: 3514: 3499: 1399: 1395: 1336: 1198: 1164: 1014: 1002: 988: 952: 920: 892: 458: 393: 373: 162: 2615: 9869: 9655: 9640: 9630: 9618: 9487: 9477: 9463: 9277: 9143: 9119: 9078: 8943: 8732: 8665: 8642: 8591: 8587: 8583: 8523: 8497: 8357: 8317: 8297: 8277: 8267: 8207: 8202: 8016: 7978: 7928: 7893: 7858: 7853: 7837: 7832: 7812: 7807: 7802: 7789: 7677: 7485: 7362: 7348: 7323: 7318: 7308: 7280: 7067: 7062: 7042: 7022: 7017: 6817: 6772: 6752: 6717: 6707: 6594: 6549: 6539: 6444: 6339: 6319: 6235: 6095: 6086: 5980: 5732: 5461: 5431: 5357: 5292: 5147: 5124: 5119: 5084: 4937: 4869: 4731: 4646: 4550: 4546: 4444: 4284: 4202: 4101: 3915: 3910: 3816: 3795: 3790: 3780: 3760: 3565: 2321: 2192: 1480:
In Iceland, flunitrazepam is a controlled substance available from
1332: 1328: 1222: 1095: 1072: 1033: 1022: 998: 916: 888: 872: 861: 830: 572: 503: 3433: 2227: 1411:
robbery a more commonly reported problem than drug-assisted rape.
738: 9766: 9598: 9267: 9213: 9151: 9054: 8958: 8904: 8896: 8881: 8860: 8855: 8679: 8669: 8428: 8367: 8342: 8337: 8212: 8192: 8172: 7993: 7983: 7968: 7953: 7938: 7923: 7918: 7903: 7888: 7769: 7508: 7368: 6822: 6529: 6230: 6040: 5777: 5591: 5466: 5362: 5269: 4988: 4721: 4253: 4131: 4091: 4086: 3050:. Forensic Science and Medicine. Humana Press. pp. 127–144. 1402:
were the two most common benzodiazepines utilized for date rape.
1317: 1243:
Flunitrazepam has a melting point of around 170 degrees Celsius.
1122: 964: 2926: 2524:"Flunitrazepam (Rohypnol) Fact Sheet & Harm Reduction Guide" 2309:
European Monitoring Centre for Drugs and Drug Addiction (EMCDDA)
1081:
Impairment of driving skills with a resultant increased risk of
1025:-like effect which can persist to the next day. It also impairs 868:. These were also the uses for which it was originally studied. 9594: 8912: 8868: 8612: 8575: 8197: 8150: 8021: 8003: 7963: 7647: 7445: 6091: 5243: 5139: 1885: 1308: 1206: 1126: 603: 398: 3044:"Analysis of Urine Samples in Cases of Alleged Sexual Assault" 2322:
Zevzikovas A, Kiliuviene G, Ivanauskas L, Dirse V (2002). "".
1221:
Flunitrazepam is classed as a nitro-benzodiazepine. It is the
9227: 7973: 6116: 5436: 3239: 3197:"S.I. No. 342/1993 — Misuse of Drugs (Amendment) Regulations" 3121:"List of Psychotropic Substances under International Control" 1928: 1666:"Prescribing of Benzodiazepines Alprazolam and Flunitrazepam" 1481: 1190:
While 80% of flunitrazepam that is taken orally is absorbed,
729: 583: 356: 80: 3041: 1539:, and the traveler may face criminal charges or deportation. 1502:
In the United States, the drug has not been approved by the
1288: 1280: 628: 9687: 9559: 9232: 7406: 4583: 1176: 852: 563: 2157: 1984:. University of Maryland. October 29, 2013. Archived from 9173: 4310: 2547: 110: 104: 98: 86: 2033: 1998: 3042:
El-Sohly MA, Lee LF, Holzhauer LB, Salamone SJ (2001).
2956:
The American Journal of Forensic Medicine and Pathology
2891: 2279:"Guidance for healthcare professionals on drug driving" 307:
Schedule IV (Schedule I trafficking penalties, however)
6162: 3338:
Farmaceutiska Specialiteter i Sverige (FASS) Allmänhet
2953: 2848: 2425: 9698: 5956: 2783: 1820:. RAD-AR Council, Japan. October 2015. Archived from 1719: 1438:
In France, as of 2016 flunitrazepam was not marketed.
101: 83: 74: 71: 3179:"Flunitrazepam - Anwendung, Wirkung, Nebenwirkungen" 2574: 2272: 2270: 1755:
Gautam L, Sharratt SD, Cole MD (February 19, 2014).
107: 95: 92: 77: 3141: 2396: 491: 113: 89: 1754: 1367: 8715:Unsorted benzodiazepine site positive modulators: 3078:: CS1 maint: DOI inactive as of September 2024 ( 2517: 2515: 2267: 9959: 2646: 2468: 1275: 471: 8795: 2575:Griffin CE, Kaye AM, Bueno FR, Kaye AD (2014). 2506:Disposition of Toxic Drugs and Chemicals in Man 2348: 2110: 2108: 1692: 1284:Hypnodorm 1 mg flunitrazepam tablets, Australia 1029:functions similar to other benzodiazepines and 446: 4545: 2512: 9968:GABAA receptor positive allosteric modulators 9857: 9744: 8781: 6148: 5560:Serotonin antagonists and reuptake inhibitors 4531: 3449: 3401:United States Drug Enforcement Administration 3314:(in Swedish). Sweden: Medical Products Agency 1922: 2727: 2419: 2105: 1842: 6164: 5949: 2820: 2462: 2392: 2390: 2388: 2386: 2384: 2382: 2380: 1441:In Germany, as of 2016 flunitrazepam is an 1405: 8788: 8774: 6155: 6141: 4538: 4524: 3456: 3442: 3260: 2682:Sternbach, L.; et al. (May 1, 1963). 2397:Kiss B, Bodoki E, Pop A, Loghin F (2016). 1628: 1626: 1255:as part of the benzodiazepine work led by 993:Benzodiazepines such as flunitrazepam are 665: 642: 531: 3354:[Flunitrazepam is discontinued]. 3201:Irish Statute Book, Statutory Instruments 2996: 2786:European Journal of Clinical Pharmacology 2681: 2592: 2250: 2151: 2114: 1818:"Kusuri-no-Shiori Drug Information Sheet" 1790: 1780: 1675:. New South Wales Health. November 2013. 1660: 1658: 1656: 1654: 1461:In Mexico, Rohypnol is legally available. 1304:European Journal of Clinical Pharmacology 1141:, which thus can be used as a treatment. 1129:. Flunitrazepam overdose responds to the 551: 9946:Ionotropic glutamate receptor modulators 8825: 3092: 2377: 1972: 1970: 1968: 1634:"International brands for Flunitrazepam" 1558: 1470: 1287: 1279: 943:in some individuals, including anxiety, 851: 3242:Tidsskrift for den Norske Laegeforening 2405:. London: Academic Press. p. 513. 1812: 1810: 1623: 1585:from the original on September 8, 2017. 1355:for benzodiazepines and similar drugs. 638: 511: 14: 9960: 3025:"Mijailovic var påverkad av våldsdrog" 2999:"Bankrånare stärkte sig med Rohypnol?" 2521: 2503: 2399:"Chapter 48: Assays for Flunitrazepam" 1699:. John Wiley & Sons. p. 53X. 1686: 1651: 1595: 1270: 1194:in suppository form is closer to 50%. 1066: 1005:, also known as floppy baby syndrome. 934: 771:CN1C(=O)CN=C(c2ccccc2F)c2cc((=O))ccc21 656: 312: 288: 9703:Tooltip N-Methyl-D-aspartate receptor 8769: 6136: 4519: 3437: 2756: 2299: 2297: 2295: 2068: 1965: 1931:Scandinavian Journal of Public Health 1425:Convention on Psychotropic Substances 1394:In a 2001 study, the benzodiazepines 611: 591: 421:5-(2-fluorophenyl)-1-methyl-7-nitro-1 300: 9978:Drugs developed by Hoffmann-La Roche 9395:4-hydroxyquinoline-3-carboxylic acid 9253:4-Phenyl-4-formyl-N-methylpiperidine 8756:GABA metabolism/transport modulators 2828:"Classification of controlled drugs" 2522:Santos, Enrique (October 13, 2022). 1807: 1564: 284:(Special prescription form required) 212: 9218:trichloroethane (methyl chloroform) 8373:Trichloroethane (methyl chloroform) 3463: 3095:"'Rape drug' used to rob thousands" 1982:Center for Substance Abuse Research 1888:Acta Anaesthesiologica Scandinavica 1682:from the original on June 23, 2014. 1611:from the original on August 3, 2023 1296: 571: 462: 24: 9822:Pesampator (BIIB-104, PF-04958242) 7436:11-Methoxy-12-hydroxydehydrokavain 2292: 2276:UK Dept. of Transport. July 2014. 2195:Annales Pharmaceutiques Françaises 1900:10.1111/j.1399-6576.1976.tb05015.x 913:benzodiazepine withdrawal syndrome 878: 25: 10014: 8183:Acetylglycinamide chloral hydrate 5265:Acetylglycinamide chloral hydrate 4500:* atypical activity profile (not 4438:Tetrahydroisoquinobenzodiazepines 3417: 1937:(3). SAGE Publications: 224–228. 1378:Flunitrazepam is known to induce 755:170–172 °C (338–342 °F) 239: 147: 3093:Thompson T (December 19, 2004). 2968:10.1097/00000433-199309000-00012 2129:10.2165/00023210-200418050-00003 2083:10.2165/00003495-198223050-00002 1857:10.2165/00003495-198020050-00002 1734:10.1097/00007611-200093060-00002 1568:Principles of addiction medicine 1251:Flunitrazepam was discovered at 911:. Discontinuation may result in 699: 696: 690: 67: 49: 40: 10003:Drug-facilitated sexual assault 8603:Menthyl isovalerate (validolum) 4480:Alprazolam triazolobenzophenone 3389: 3380: 3362: 3344: 3326: 3304: 3278: 3233: 3207: 3189: 3171: 3153:Statutory Medical Notifications 3113: 3086: 3058:(inactive September 11, 2024). 3035: 3017: 2990: 2947: 2920: 2885: 2842: 2777: 2750: 2732:. Weinheim: Wiley-VCH. p.  2721: 2675: 2640: 2622:Drug Metabolism and Disposition 2609: 2568: 2541: 2497: 2342: 2315: 2221: 2186: 2062: 2048:10.1016/j.forsciint.2005.06.009 2027: 1992: 1879: 1693:Fischer J, Ganellin CR (2006). 1414: 1374:Drug facilitated sexual assault 1368:Drug-facilitated sexual assault 1170: 1165:3-hydroxydesmethylflunitrazepam 1089: 1043:Other adverse effects include: 796:Key:PPTYJKAXVCCBDU-UHFFFAOYSA-N 374:3-hydroxydesmethylflunitrazepam 276: 7552:Allopregnanolone (brexanolone) 2351:Forensic Science International 2305:"Benzodiazepines drug profile" 2036:Forensic Science International 1836: 1748: 1713: 1673:Pharmaceutical Services Branch 1589: 705: 684: 319:Psychotropic Schedule III 265: 252: 13: 1: 9921:Receptor/signaling modulators 9862:Tooltip Glycine transporter 2 9772:Bitopertin (RG1678/RO4917838) 9749:Tooltip Glycine transporter 1 8748:Receptor/signaling modulators 7304:Ampelopsin (dihydromyricetin) 2730:Analogue-Based Drug Discovery 2363:10.1016/S0379-0738(01)00632-6 1696:Analogue-based Drug Discovery 1552: 1423:drug under the international 1276:Recreational and illegal uses 1240:(2ʹ-chlorinated derivative). 1236:(methylamino derivative) and 1051:Gastrointestinal disturbances 903:Flunitrazepam, as with other 898: 864:, and in some countries as a 9973:Glycine receptor antagonists 9939:receptor positive modulators 8498:ergoloid (dihydroergotoxine) 7583:anabolic-androgenic steroids 6365:Butabarbital/Secbutabarbital 6170:receptor positive modulators 2997:Liljesson S (June 3, 1999). 2894:Journal of Forensic Sciences 2863:10.1097/FTD.0b013e31803d3c04 2688:Journal of Medical Chemistry 2649:Journal of Forensic Sciences 2471:Journal of Forensic Sciences 2440:10.1097/FTD.0b013e31803d3c04 2286:The Department for Transport 2207:10.1016/j.pharma.2009.07.001 1782:10.1371/journal.pone.0089031 1504:Food and Drug Administration 1216: 1144: 1086:after taking flunitrazepam. 982: 821:, sold under the brand name 7: 7138:Triflunordazepam (Ro5-2904) 5791:Tetracyclic antidepressants 5605:Tetracyclic antidepressants 2851:Therapeutic Drug Monitoring 2428:Therapeutic Drug Monitoring 2243:10.1016/j.sleep.2007.11.011 1607:(published April 4, 2023). 1506:and is considered to be an 1262:Due to use of the drug for 1213:in human liver microsomes. 1181:inhibitory neurotransmitter 1101: 973:Paradoxical adverse effects 10: 10019: 8977:chlorobutanol (chloretone) 7466:5,6,7,8-Tetrahydroyangonin 3001:. DrugNews. Archived from 2763:The Pharmaceutical Journal 2757:Bryan J (September 2009). 2172:10.1016/j.smrv.2009.10.008 1978:"Flunitrazepam (Rohypnol)" 1371: 1358: 1246: 1209:is the main enzyme in its 1105: 1053:, lasting 12 or more hours 986: 939:Flunitrazepam may cause a 674:Chemical and physical data 9912: 9855: 9742: 9725: 9696: 9092:pregnenolone (eltanolone) 9069:Glutamic acid (glutamate) 8823: 8806: 8741: 8391: 8159: 8096: 8063: 8030: 8002: 7716: 7658:Pregnanolone (eltanolone) 7537: 7494: 7405: 7377: 7289: 7171: 6613: 6300: 6201:Chlorobutanol (cloretone) 6176: 5994: 5947: 5919: 5886: 5866: 5812: 5768:Tricyclic antidepressants 5753: 5741: 5684: 5626: 5582:Tricyclic antidepressants 5550: 5487: 5475: 5404: 5252: 5189: 5156: 5138: 5070: 5017: 4974: 4946: 4888: 4765: 4622: 4574: 4562: 4498: 4472: 4453: 4437: 4421: 4383: 4365: 4349: 4325: 4239: 4211: 4175: 4069: 3975: 3934: 3898: 3471: 3185:. Vidal MMI Germany GmbH. 3056:10.1007/978-1-59259-109-1 1943:10.1080/14034940210167966 1197:Flunitrazepam has a long 804: 779: 759: 749: 727: 714: 678: 673: 654: 622: 602: 582: 562: 542: 522: 502: 482: 457: 437: 409: 404: 392: 379: 362: 350: 338: 330: 229: 224: 199: 187: 173: 161: 135: 125: 62: 57: 48: 39: 9993:2-Fluorophenyl compounds 9928:GABA receptor modulators 8830:Tooltip Glycine receptor 8752:GABA receptor modulators 8662:sulfonmethane (sulfonal) 5353:Sulfonmethane (sulfonal) 4367:Pyridotriazolodiazepines 4241:Thienotriazolodiazepines 3358:(in Swedish). Stockholm. 2013:10.1001/jama.241.16.1692 1722:Southern Medical Journal 1543: 1406:Drug-facilitated robbery 1008: 9573:3β-androsterone sulfate 9569:3α-androsterone sulfate 5840:Atypical antipsychotics 5654:Atypical antipsychotics 4473:Benzodiazepine prodrugs 3977:Triazolobenzodiazepines 3272:Drug Wars – About Drugs 3048:Benzodiazepines and GHB 1605:Diário Oficial da União 1475:Icelandic Flunitrazepam 1353:potential for addiction 1108:Benzodiazepine overdose 27:Benzodiazepine sedative 9817:ORG-25935 (SCH-900435) 9006:Alkylbenzene sulfonate 8638:Retigabine (ezogabine) 7914:Lirequinil (Ro41-3696) 7481:7,8-Dihydromethysticin 7471:5,6-Dehydromethysticin 6350:Benzylbutylbarbiturate 6014:Chlorophenylalkyldiols 5822:Typical antipsychotics 5636:Typical antipsychotics 4455:Pyrrolobenzodiazepines 4176:Oxazolobenzodiazepines 4070:Imidazobenzodiazepines 4053:(active metabolite of 3555:Desmethylflunitrazepam 2550:Arzneimittel-Forschung 2401:. In Preedy VR (ed.). 2160:Sleep Medicine Reviews 1476: 1301:A 1989 article in the 1293: 1285: 1228:-methyl derivative of 1161:desmethylflunitrazepam 1115:respiratory depression 1083:road traffic accidents 1060:Respiratory depression 857: 856:Rohypnol 1 mg tablets. 847: 370:desmethylflunitrazepam 368:7-aminoflunitrazepam, 9890:Opiranserin (VVZ-149) 9190:diethyl ether (ether) 4327:Thienobenzodiazepines 3424:Molecule of the Month 3352:"Flunitrazepam utgår" 3286:"Flunitrazepam Mylan" 3005:on September 29, 2007 2773:on November 20, 2015. 2769:: 305. Archived from 1474: 1291: 1283: 1076:psychiatric disorders 855: 829:used to treat severe 9988:Nitrobenzodiazepines 9585:pregnenolone sulfate 9565:Neuroactive steroids 9523:constituents (e.g., 9483:Cyanotriphenylborate 9444:Negative modulators: 9367:N,N-Dimethylmuscimol 9293:Cyanotriphenylborate 9130:Tetrahydrocannabinol 9096:pregnenolone acetate 9084:Neuroactive steroids 9057:constituents (e.g., 8966:Positive modulators: 8693:constituents (e.g., 8477:Deuterated etifoxine 7539:Neuroactive steroids 7509:Apronal (apronalide) 7361:constituents (e.g., 6978:N-Desalkylflurazepam 5971:Gabapentin enacarbil 5019:Neuroactive steroids 4989:Apronal (apronalide) 3935:2,3-Benzodiazepines* 941:paradoxical reaction 261:(Psychoactive drugs) 9577:deoxycorticosterone 9357:N-Methylbicuculline 8486:dihydroergocryptine 7798:Pyrazolopyrimidines 7456:5,6-Dihydroyangonin 7441:7,8-Dihydroyangonin 6628:3-Hydroxyphenazepam 6470:Methylphenobarbital 4275:Deschloroclotizolam 3899:1,5-Benzodiazepines 3721:-Desalkylflurazepam 3484:3-Hydroxyphenazepam 3472:1,4-Benzodiazepines 3274:. October 11, 2006. 3215:"What is Rohypnol?" 2700:10.1021/jm00339a010 2581:The Ochsner Journal 1988:on January 9, 2016. 1773:2014PLoSO...989031G 1510:; as of 2016 it is 1419:Flunitrazepam is a 1380:anterograde amnesia 1349:pyrazolopyrimidines 1271:Society and culture 1067:Special precautions 1019:anterograde amnesia 967:behavior, and even 935:Paradoxical effects 915:, characterised by 866:preanesthetic agent 825:among others, is a 36: 9787:Glycyldodecylamide 9391:4-hydroxyquinoline 9362:N-Methylstrychnine 8580:4-O-methylhonokiol 8243:Dichloralphenazone 8141:Methylmethaqualone 7718:Nonbenzodiazepines 7431:Desmethoxyyangonin 7426:11-Hydroxyyangonin 7421:11-Methoxyyangonin 7416:10-Methoxyyangonin 6803:Ethyl carfluzepate 6405:Cyclopentobarbital 6036:Diethylpropanediol 5318:Dichloralphenazone 5234:Methylmethaqualone 5072:Nonbenzodiazepines 4599:Diethylpropanediol 4384:Pyrazolodiazepines 3591:Ethyl carfluzepate 3290:Lyfja - Lifið heil 3159:on August 28, 2006 2798:10.1007/BF00637747 2311:. January 8, 2015. 1599:(March 31, 2023). 1537:search and seizure 1477: 1294: 1286: 1211:phase 1 metabolism 977:criminal behaviour 858: 425:-benzodiazepin-2(3 323:SE: Förteckning II 32: 9955: 9954: 9908: 9907: 9880:Ethanol (alcohol) 9782:Ethanol (alcohol) 9736: 9721: 9720: 9342:Isonipecotic acid 9248:2-Nitrostrychnine 9243:2-Aminostrychnine 9222:trichloroethylene 9024:sodium thiopental 8981:ethanol (alcohol) 8923: 8915: 8907: 8899: 8871: 8863: 8817: 8763: 8762: 8723:MRK-409 (MK-0343) 8494:dihydroergotamine 8437:potassium bromide 8431:compounds (e.g., 8378:Trichloroethylene 8146:Nitromethaqualone 8065:Pyrazolopyridines 7567:3α-Androstanediol 7461:7,8-Dihydrokavain 6813:Ethyl loflazepate 6590:Thiotetrabarbital 6206:Ethanol (alcohol) 6130: 6129: 5882: 5881: 5680: 5679: 5400: 5399: 5281:Potassium bromide 5239:Nitromethaqualone 4747:Thiotetrabarbital 4594:Ethanol (alcohol) 4513: 4512: 4422:Pyrrolodiazepines 4280:Deschloroetizolam 4249:α-Hydroxyetizolam 3601:Ethyl loflazepate 3376:. August 8, 2022. 3219:12 South Recovery 3137:on July 13, 2017. 2935:(45): 3954–3957. 2906:10.1520/JFS14633J 2743:978-3-527-60749-5 2661:10.1520/JFS13791J 2556:(12): 2383–2388. 2504:Baselt R (2008). 2483:10.1520/JFS16081J 2412:978-0-12-800375-6 2007:(16): 1692–1695. 1578:978-0-7817-7477-2 1031:nonbenzodiazepine 975:may even lead to 963:, talkativeness, 862:sleeping problems 816: 815: 740:Interactive image 624:CompTox Dashboard 346:50% (suppository) 344:64–77% (by mouth) 316: 304: 292: 279: 268: 256: 248:(Controlled drug) 243: 151: 16:(Redirected from 10010: 9863: 9859: 9750: 9746: 9740: 9739: 9730: 9704: 9700: 9603:dextromethorphan 9493:Dihydropyridines 9432:Thiocolchicoside 9382:Pseudostrychnine 9322:Gaboxadol (THIP) 9316:anandamide (AEA) 9308:Endocannabinoids 9040:Dihydropyridines 9000:trifluoroethanol 8996:trichloroethanol 8921: 8913: 8905: 8897: 8869: 8861: 8831: 8827: 8821: 8820: 8811: 8797:Glycine receptor 8790: 8783: 8776: 8767: 8766: 8482:Dihydroergolines 8399:3-Hydroxybutanal 8032:Piperidinediones 7765:Imidazopyridines 7299:6-Methylapigenin 7231:Hydroxyphenamate 7103:SH-053-R-CH3-2′F 6808:Ethyl dirazepate 6688:Chlordiazepoxide 6580:Thiobutabarbital 6292:Trifluoroethanol 6282:Trichloroethanol 6272:-Pentanol (2M2B) 6166: 6157: 6150: 6143: 6134: 6133: 6055:muscle relaxants 5958: 5955: 5751: 5750: 5485: 5484: 5422:4-Fluorophenibut 5158:Piperidinediones 5032:Allopregnanolone 4614:Trichloroethanol 4572: 4571: 4540: 4533: 4526: 4517: 4516: 4350:Pyridodiazepines 4213:Thienodiazepines 4167:SH-053-R-CH3-2′F 3880:Triflunordazepam 3596:Ethyl dirazepate 3510:Chlordiazepoxide 3458: 3451: 3444: 3435: 3434: 3412: 3411: 3409: 3407: 3393: 3387: 3384: 3378: 3377: 3366: 3360: 3359: 3348: 3342: 3341: 3330: 3324: 3323: 3321: 3319: 3308: 3302: 3301: 3299: 3297: 3282: 3276: 3275: 3264: 3258: 3257: 3237: 3231: 3230: 3228: 3226: 3211: 3205: 3204: 3193: 3187: 3186: 3175: 3169: 3168: 3166: 3164: 3145: 3139: 3138: 3136: 3125: 3117: 3111: 3110: 3108: 3106: 3090: 3084: 3083: 3077: 3069: 3039: 3033: 3032: 3021: 3015: 3014: 3012: 3010: 2994: 2988: 2987: 2951: 2945: 2944: 2924: 2918: 2917: 2889: 2883: 2882: 2846: 2840: 2839: 2837: 2835: 2824: 2818: 2817: 2781: 2775: 2774: 2754: 2748: 2747: 2725: 2719: 2718: 2716: 2714: 2679: 2673: 2672: 2644: 2638: 2637: 2613: 2607: 2606: 2596: 2572: 2566: 2565: 2545: 2539: 2538: 2536: 2534: 2519: 2510: 2509: 2501: 2495: 2494: 2466: 2460: 2459: 2423: 2417: 2416: 2394: 2375: 2374: 2346: 2340: 2339: 2319: 2313: 2312: 2301: 2290: 2289: 2283: 2274: 2265: 2264: 2254: 2225: 2219: 2218: 2190: 2184: 2183: 2155: 2149: 2148: 2112: 2103: 2102: 2066: 2060: 2059: 2031: 2025: 2024: 1996: 1990: 1989: 1974: 1963: 1962: 1926: 1920: 1919: 1883: 1877: 1876: 1840: 1834: 1833: 1831: 1829: 1824:on March 3, 2016 1814: 1805: 1804: 1794: 1784: 1752: 1746: 1745: 1717: 1711: 1710: 1690: 1684: 1683: 1681: 1670: 1662: 1649: 1648: 1646: 1644: 1630: 1621: 1620: 1618: 1616: 1593: 1587: 1586: 1565:Ries RK (2009). 1562: 1446:Betäubungsmittel 1345:imidazopyridines 1297:Recreational use 929:Rebound insomnia 923:, insomnia, and 833:and assist with 812: 811: 742: 722: 707: 701: 698: 692: 686: 669: 658: 647: 646: 632: 630: 615: 595: 575: 555: 535: 515: 495: 475: 465: 464: 450: 384: 314: 311: 302: 299: 290: 287: 278: 275: 267: 264: 254: 251: 241: 238: 216: 149: 146: 120: 119: 116: 115: 112: 109: 106: 103: 100: 97: 94: 91: 88: 85: 82: 79: 76: 73: 53: 44: 37: 35: 31: 21: 10018: 10017: 10013: 10012: 10011: 10009: 10008: 10007: 9958: 9957: 9956: 9951: 9938: 9904: 9861: 9851: 9762:ALX-5407 (NFPS) 9748: 9729: 9717: 9702: 9692: 9452:Benzodiazepines 9337:Isobutyric acid 9178:chloral hydrate 9030:Chlormethiazole 8992:tribromoethanol 8988:-butanol (2M2P) 8829: 8810: 8802: 8794: 8764: 8759: 8737: 8695:isovaleric acid 8658:Sulfonylalkanes 8556:Hopantenic acid 8540:tolfenamic acid 8528:flufenamic acid 8490:dihydroergosine 8433:lithium bromide 8392:Others/unsorted 8387: 8248:Dichloromethane 8223:Chloral hydrate 8218:Chloral betaine 8155: 8092: 8059: 8026: 7998: 7727:Cyclopyrrolones 7712: 7618:Etiocholanolone 7533: 7490: 7451:5-Hydroxykavain 7401: 7373: 7285: 7167: 6615:Benzodiazepines 6609: 6420:Ethallobarbital 6415:Enallylpropymal 6296: 6277:Tribromoethanol 6264:-Butanol (2M2P) 6210:alcoholic drink 6172: 6169: 6161: 6131: 6126: 5990: 5953: 5943: 5915: 5878: 5862: 5808: 5755:Antidepressants 5746: 5737: 5708:Dexmedetomidine 5689: 5676: 5622: 5552:Antidepressants 5546: 5507:Diphenhydramine 5480: 5471: 5409: 5396: 5385:Isovaleric acid 5348:Sulfonylalkanes 5303:Chloral hydrate 5298:Chloral betaine 5276:Lithium bromide 5248: 5185: 5152: 5134: 5066: 5013: 4970: 4942: 4884: 4767:Benzodiazepines 4761: 4667:Ethallobarbital 4618: 4567: 4558: 4544: 4514: 4509: 4505: 4494: 4468: 4449: 4433: 4417: 4379: 4361: 4345: 4321: 4235: 4207: 4171: 4065: 3971: 3930: 3894: 3467: 3465:Benzodiazepines 3462: 3420: 3415: 3405: 3403: 3395: 3394: 3390: 3385: 3381: 3368: 3367: 3363: 3350: 3349: 3345: 3332: 3331: 3327: 3317: 3315: 3312:"Flunitrazepam" 3310: 3309: 3305: 3295: 3293: 3284: 3283: 3279: 3266: 3265: 3261: 3238: 3234: 3224: 3222: 3213: 3212: 3208: 3195: 3194: 3190: 3177: 3176: 3172: 3162: 3160: 3147: 3146: 3142: 3134: 3123: 3119: 3118: 3114: 3104: 3102: 3091: 3087: 3071: 3070: 3066: 3040: 3036: 3023: 3022: 3018: 3008: 3006: 2995: 2991: 2952: 2948: 2925: 2921: 2890: 2886: 2847: 2843: 2833: 2831: 2826: 2825: 2821: 2782: 2778: 2755: 2751: 2744: 2726: 2722: 2712: 2710: 2680: 2676: 2645: 2641: 2614: 2610: 2573: 2569: 2546: 2542: 2532: 2530: 2520: 2513: 2502: 2498: 2467: 2463: 2424: 2420: 2413: 2395: 2378: 2347: 2343: 2320: 2316: 2303: 2302: 2293: 2288:. London. 2014. 2281: 2277: 2275: 2268: 2226: 2222: 2191: 2187: 2156: 2152: 2113: 2106: 2067: 2063: 2032: 2028: 1997: 1993: 1976: 1975: 1966: 1927: 1923: 1884: 1880: 1841: 1837: 1827: 1825: 1816: 1815: 1808: 1753: 1749: 1718: 1714: 1707: 1691: 1687: 1679: 1668: 1664: 1663: 1652: 1642: 1640: 1632: 1631: 1624: 1614: 1612: 1594: 1590: 1579: 1563: 1559: 1555: 1546: 1417: 1408: 1376: 1370: 1361: 1341:cyclopyrrolones 1299: 1278: 1273: 1249: 1219: 1192:bioavailability 1173: 1147: 1134: 1119:CNS depressants 1110: 1104: 1092: 1069: 1062:in higher doses 1011: 991: 985: 961:impulse control 937: 909:drug dependence 905:benzodiazepines 901: 881: 879:Adverse effects 850: 807: 805: 800: 797: 792: 787: 786: 775: 772: 767: 766: 745: 720: 710: 704: 695: 689: 650: 626: 618: 598: 578: 558: 538: 518: 498: 478: 461: 453: 433: 430: 417: 416: 382: 345: 340:Bioavailability 332:Pharmacokinetic 326: 220: 176: 164: 157: 138: 70: 66: 28: 23: 22: 15: 12: 11: 5: 10016: 10006: 10005: 10000: 9995: 9990: 9985: 9980: 9975: 9970: 9953: 9952: 9950: 9949: 9942: 9936: 9931: 9924: 9917: 9913: 9910: 9909: 9906: 9905: 9903: 9902: 9897: 9892: 9887: 9882: 9877: 9872: 9866: 9864: 9853: 9852: 9850: 9849: 9844: 9839: 9834: 9829: 9824: 9819: 9814: 9809: 9804: 9799: 9794: 9789: 9784: 9779: 9774: 9769: 9764: 9759: 9753: 9751: 9737: 9723: 9722: 9719: 9718: 9716: 9715: 9707: 9705: 9694: 9693: 9691: 9690: 9685: 9680: 9658: 9653: 9648: 9634: 9592: 9562: 9557: 9552: 9518: 9513: 9508: 9490: 9485: 9480: 9475: 9449: 9440: 9439: 9434: 9429: 9424: 9419: 9414: 9384: 9379: 9374: 9372:Nipecotic acid 9369: 9364: 9359: 9354: 9349: 9344: 9339: 9334: 9329: 9324: 9319: 9305: 9300: 9295: 9290: 9285: 9280: 9275: 9270: 9265: 9260: 9255: 9250: 9245: 9236: 9235: 9230: 9225: 9206:methoxyflurane 9167: 9137: 9132: 9127: 9122: 9117: 9112: 9107: 9081: 9076: 9071: 9066: 9063:ginsenoside-Rf 9052: 9047: 9037: 9032: 9027: 9013: 9008: 9003: 8962: 8961: 8956: 8951: 8946: 8941: 8939:Picolinic acid 8936: 8931: 8926: 8918: 8910: 8902: 8894: 8889: 8884: 8879: 8874: 8866: 8858: 8853: 8848: 8843: 8834: 8832: 8818: 8804: 8803: 8793: 8792: 8785: 8778: 8770: 8761: 8760: 8742: 8739: 8738: 8736: 8735: 8730: 8725: 8720: 8711: 8710: 8703:valerenic acid 8688: 8683: 8673: 8655: 8650: 8645: 8640: 8635: 8630: 8625: 8620: 8615: 8610: 8605: 8600: 8595: 8573: 8568: 8563: 8558: 8553: 8548: 8543: 8532:mefenamic acid 8521: 8516: 8511: 8506: 8501: 8479: 8474: 8469: 8464: 8459: 8454: 8449: 8444: 8441:sodium bromide 8426: 8416: 8411: 8406: 8401: 8395: 8393: 8389: 8388: 8386: 8385: 8380: 8375: 8370: 8365: 8360: 8355: 8350: 8345: 8340: 8335: 8330: 8325: 8320: 8315: 8310: 8308:Methoxypropane 8305: 8303:Methoxyflurane 8300: 8295: 8290: 8285: 8280: 8275: 8270: 8265: 8263:Ethyl chloride 8260: 8255: 8250: 8245: 8240: 8235: 8230: 8225: 8220: 8215: 8210: 8205: 8200: 8195: 8190: 8185: 8180: 8175: 8169: 8167: 8157: 8156: 8154: 8153: 8148: 8143: 8138: 8133: 8128: 8123: 8118: 8113: 8108: 8102: 8100: 8098:Quinazolinones 8094: 8093: 8091: 8090: 8085: 8080: 8075: 8069: 8067: 8061: 8060: 8058: 8057: 8052: 8047: 8042: 8036: 8034: 8028: 8027: 8025: 8024: 8019: 8014: 8008: 8006: 8000: 7999: 7997: 7996: 7991: 7986: 7981: 7976: 7971: 7966: 7961: 7956: 7951: 7946: 7941: 7936: 7931: 7926: 7921: 7916: 7911: 7906: 7901: 7896: 7891: 7886: 7881: 7876: 7871: 7866: 7861: 7856: 7851: 7841: 7840: 7835: 7830: 7825: 7820: 7815: 7810: 7805: 7793: 7792: 7787: 7782: 7777: 7772: 7760: 7759: 7754: 7749: 7744: 7739: 7734: 7722: 7720: 7714: 7713: 7711: 7710: 7705: 7700: 7695: 7690: 7685: 7680: 7675: 7670: 7665: 7660: 7655: 7650: 7645: 7640: 7635: 7630: 7625: 7620: 7615: 7610: 7605: 7600: 7595: 7590: 7585: 7579: 7574: 7569: 7564: 7559: 7554: 7549: 7543: 7541: 7535: 7534: 7532: 7531: 7526: 7521: 7516: 7511: 7506: 7500: 7498: 7492: 7491: 7489: 7488: 7483: 7478: 7473: 7468: 7463: 7458: 7453: 7448: 7443: 7438: 7433: 7428: 7423: 7418: 7412: 7410: 7403: 7402: 7400: 7399: 7394: 7389: 7383: 7381: 7375: 7374: 7372: 7371: 7366: 7356: 7351: 7346: 7341: 7336: 7331: 7326: 7321: 7316: 7311: 7306: 7301: 7295: 7293: 7287: 7286: 7284: 7283: 7278: 7273: 7268: 7263: 7258: 7253: 7248: 7243: 7238: 7233: 7228: 7223: 7218: 7213: 7208: 7203: 7198: 7193: 7188: 7183: 7177: 7175: 7169: 7168: 7166: 7165: 7160: 7155: 7150: 7145: 7140: 7135: 7130: 7125: 7120: 7115: 7110: 7105: 7100: 7095: 7090: 7085: 7080: 7075: 7070: 7065: 7060: 7055: 7050: 7045: 7040: 7035: 7030: 7025: 7020: 7015: 7010: 7005: 7000: 6995: 6990: 6985: 6980: 6975: 6970: 6965: 6960: 6955: 6950: 6945: 6940: 6935: 6930: 6925: 6920: 6915: 6910: 6905: 6900: 6895: 6890: 6885: 6880: 6875: 6870: 6865: 6860: 6855: 6850: 6845: 6840: 6835: 6830: 6825: 6820: 6815: 6810: 6805: 6800: 6795: 6790: 6785: 6780: 6775: 6770: 6765: 6760: 6755: 6750: 6745: 6740: 6735: 6730: 6725: 6720: 6715: 6710: 6705: 6700: 6695: 6690: 6685: 6680: 6675: 6670: 6665: 6660: 6655: 6650: 6645: 6640: 6635: 6630: 6625: 6619: 6617: 6611: 6610: 6608: 6607: 6602: 6597: 6592: 6587: 6582: 6577: 6572: 6567: 6562: 6557: 6552: 6547: 6542: 6537: 6532: 6527: 6522: 6520:Propylbarbital 6517: 6512: 6507: 6502: 6497: 6492: 6487: 6482: 6477: 6472: 6467: 6462: 6457: 6452: 6447: 6442: 6437: 6432: 6427: 6422: 6417: 6412: 6407: 6402: 6397: 6395:Crotylbarbital 6392: 6387: 6382: 6377: 6372: 6367: 6362: 6360:Brophebarbital 6357: 6355:Brallobarbital 6352: 6347: 6342: 6337: 6332: 6327: 6322: 6317: 6312: 6306: 6304: 6298: 6297: 6295: 6294: 6289: 6284: 6279: 6274: 6266: 6258: 6253: 6248: 6243: 6241:Methylpentynol 6238: 6233: 6228: 6223: 6218: 6213: 6203: 6198: 6193: 6188: 6182: 6180: 6174: 6173: 6167: 6160: 6159: 6152: 6145: 6137: 6128: 6127: 6125: 6124: 6119: 6114: 6109: 6104: 6102:Passion flower 6099: 6089: 6084: 6083: 6082: 6077: 6072: 6067: 6062: 6048: 6043: 6038: 6033: 6032: 6031: 6026: 6021: 6011: 6010: 6009: 5998: 5996: 5992: 5991: 5989: 5988: 5983: 5978: 5973: 5968: 5962: 5960: 5951: 5945: 5944: 5942: 5941: 5936: 5931: 5925: 5923: 5917: 5916: 5914: 5913: 5908: 5903: 5898: 5892: 5890: 5884: 5883: 5880: 5879: 5877: 5876: 5870: 5868: 5864: 5863: 5861: 5860: 5859: 5858: 5852: 5847: 5837: 5836: 5835: 5829: 5827:Chlorpromazine 5818: 5816: 5814:Antipsychotics 5810: 5809: 5807: 5806: 5805: 5804: 5798: 5788: 5787: 5786: 5780: 5775: 5765: 5759: 5757: 5748: 5744: 5739: 5738: 5736: 5735: 5730: 5725: 5720: 5715: 5710: 5705: 5700: 5694: 5692: 5687: 5682: 5681: 5678: 5677: 5675: 5674: 5673: 5672: 5666: 5661: 5651: 5650: 5649: 5643: 5641:Chlorpromazine 5632: 5630: 5628:Antipsychotics 5624: 5623: 5621: 5620: 5619: 5618: 5612: 5602: 5601: 5600: 5594: 5589: 5579: 5578: 5577: 5572: 5567: 5556: 5554: 5548: 5547: 5545: 5544: 5539: 5534: 5529: 5524: 5519: 5514: 5509: 5504: 5502:Cyproheptadine 5499: 5493: 5491: 5489:Antihistamines 5482: 5478: 5473: 5472: 5470: 5469: 5464: 5459: 5454: 5449: 5446:sodium oxybate 5439: 5434: 5429: 5424: 5419: 5417:1,4-Butanediol 5413: 5411: 5407: 5402: 5401: 5398: 5397: 5395: 5394: 5393: 5392: 5390:Valerenic acid 5387: 5382: 5372: 5367: 5366: 5365: 5360: 5355: 5345: 5340: 5335: 5330: 5325: 5320: 5315: 5310: 5305: 5300: 5295: 5290: 5289: 5288: 5286:Sodium bromide 5283: 5278: 5267: 5262: 5256: 5254: 5250: 5249: 5247: 5246: 5241: 5236: 5231: 5226: 5221: 5216: 5211: 5206: 5201: 5195: 5193: 5191:Quinazolinones 5187: 5186: 5184: 5183: 5178: 5173: 5168: 5162: 5160: 5154: 5153: 5151: 5150: 5144: 5142: 5136: 5135: 5133: 5132: 5127: 5122: 5117: 5112: 5107: 5102: 5097: 5092: 5087: 5082: 5076: 5074: 5068: 5067: 5065: 5064: 5059: 5054: 5049: 5044: 5039: 5034: 5029: 5023: 5021: 5015: 5014: 5012: 5011: 5006: 5001: 4996: 4991: 4986: 4980: 4978: 4972: 4971: 4969: 4968: 4963: 4958: 4952: 4950: 4944: 4943: 4941: 4940: 4935: 4930: 4925: 4920: 4915: 4910: 4905: 4900: 4894: 4892: 4886: 4885: 4883: 4882: 4877: 4872: 4867: 4862: 4857: 4852: 4847: 4842: 4837: 4832: 4827: 4822: 4817: 4812: 4807: 4802: 4797: 4792: 4787: 4782: 4777: 4771: 4769: 4763: 4762: 4760: 4759: 4754: 4749: 4744: 4739: 4734: 4729: 4724: 4719: 4714: 4712:Propylbarbital 4709: 4704: 4699: 4694: 4689: 4684: 4679: 4674: 4669: 4664: 4659: 4654: 4649: 4644: 4639: 4634: 4628: 4626: 4620: 4619: 4617: 4616: 4611: 4609:Methylpentynol 4606: 4601: 4596: 4591: 4586: 4580: 4578: 4569: 4565: 4560: 4559: 4543: 4542: 4535: 4528: 4520: 4511: 4510: 4503: 4499: 4496: 4495: 4493: 4492: 4487: 4482: 4476: 4474: 4470: 4469: 4467: 4466: 4460: 4458: 4451: 4450: 4448: 4447: 4441: 4439: 4435: 4434: 4432: 4431: 4425: 4423: 4419: 4418: 4416: 4415: 4409: 4404: 4399: 4394: 4387: 4385: 4381: 4380: 4378: 4377: 4371: 4369: 4363: 4362: 4360: 4359: 4353: 4351: 4347: 4346: 4344: 4343: 4338: 4332: 4330: 4323: 4322: 4320: 4319: 4314: 4308: 4302: 4297: 4292: 4287: 4282: 4277: 4272: 4267: 4262: 4257: 4251: 4245: 4243: 4237: 4236: 4234: 4233: 4228: 4223: 4217: 4215: 4209: 4208: 4206: 4205: 4200: 4195: 4190: 4185: 4179: 4177: 4173: 4172: 4170: 4169: 4164: 4159: 4154: 4149: 4144: 4139: 4134: 4129: 4124: 4119: 4114: 4109: 4104: 4099: 4094: 4089: 4084: 4079: 4073: 4071: 4067: 4066: 4064: 4063: 4058: 4048: 4043: 4038: 4033: 4028: 4023: 4018: 4013: 4008: 4003: 3998: 3992: 3987: 3981: 3979: 3973: 3972: 3970: 3969: 3964: 3959: 3954: 3949: 3944: 3938: 3936: 3932: 3931: 3929: 3928: 3923: 3918: 3913: 3908: 3902: 3900: 3896: 3895: 3893: 3892: 3887: 3882: 3877: 3872: 3866: 3860: 3855: 3850: 3845: 3840: 3835: 3830: 3825: 3820: 3814: 3809: 3803: 3798: 3793: 3788: 3783: 3778: 3773: 3768: 3763: 3758: 3753: 3748: 3743: 3738: 3733: 3728: 3723: 3715: 3710: 3705: 3700: 3695: 3690: 3684: 3679: 3674: 3669: 3664: 3658: 3653: 3648: 3643: 3638: 3633: 3628: 3623: 3618: 3613: 3608: 3603: 3598: 3593: 3588: 3583: 3578: 3573: 3568: 3563: 3557: 3552: 3547: 3542: 3537: 3532: 3527: 3522: 3517: 3512: 3507: 3502: 3497: 3491: 3486: 3481: 3475: 3473: 3469: 3468: 3461: 3460: 3453: 3446: 3438: 3432: 3431: 3426: 3419: 3418:External links 3416: 3414: 3413: 3388: 3379: 3361: 3343: 3325: 3303: 3292:(in Icelandic) 3277: 3259: 3248:(5): 589–590. 3232: 3221:. May 27, 2019 3206: 3188: 3170: 3140: 3112: 3085: 3064: 3034: 3016: 2989: 2962:(3): 238–243. 2946: 2929:Läkartidningen 2919: 2884: 2857:(2): 248–260. 2841: 2819: 2792:(6): 621–623. 2776: 2749: 2742: 2720: 2694:(3): 261–265. 2674: 2655:(3): 382–386. 2639: 2628:(2): 133–140. 2608: 2587:(2): 214–223. 2567: 2540: 2511: 2496: 2461: 2418: 2411: 2376: 2341: 2330:(3): 316–320. 2314: 2291: 2266: 2237:(8): 818–822. 2231:Sleep Medicine 2220: 2201:(6): 408–413. 2185: 2166:(4): 259–267. 2150: 2123:(5): 297–328. 2104: 2077:(5): 354–380. 2061: 2042:(2–3): 83–91. 2026: 1991: 1964: 1921: 1878: 1851:(5): 353–374. 1835: 1806: 1747: 1728:(6): 558–561. 1712: 1705: 1685: 1650: 1622: 1588: 1577: 1556: 1554: 1551: 1545: 1542: 1541: 1540: 1524:21 U.S.C. 1516:21 U.S.C. 1500: 1489: 1485: 1469: 1468: 1465: 1462: 1459: 1452: 1449: 1439: 1436: 1416: 1413: 1407: 1404: 1385:sexual assault 1372:Main article: 1369: 1366: 1360: 1357: 1298: 1295: 1277: 1274: 1272: 1269: 1248: 1245: 1218: 1215: 1185:GABA receptors 1172: 1169: 1146: 1143: 1132: 1125:(alcohol) and 1103: 1100: 1091: 1088: 1068: 1065: 1064: 1063: 1057: 1054: 1048: 1047:Slurred speech 1010: 1007: 984: 981: 945:aggressiveness 936: 933: 907:, can lead to 900: 897: 895:of the fetus. 880: 877: 849: 846: 842:date rape drug 827:benzodiazepine 814: 813: 802: 801: 799: 798: 795: 793: 790: 782: 781: 780: 777: 776: 774: 773: 770: 762: 761: 760: 757: 756: 753: 747: 746: 744: 743: 735: 733: 725: 724: 718: 712: 711: 708: 702: 693: 687: 682: 676: 675: 671: 670: 660: 652: 651: 649: 648: 635: 633: 620: 619: 617: 616: 608: 606: 600: 599: 597: 596: 588: 586: 580: 579: 577: 576: 568: 566: 560: 559: 557: 556: 548: 546: 540: 539: 537: 536: 528: 526: 520: 519: 517: 516: 508: 506: 500: 499: 497: 496: 488: 486: 480: 479: 477: 476: 468: 466: 455: 454: 452: 451: 443: 441: 435: 434: 432: 431: 420: 412: 411: 410: 407: 406: 402: 401: 396: 390: 389: 386: 377: 376: 366: 360: 359: 354: 348: 347: 342: 336: 335: 328: 327: 325: 324: 321: 309: 297: 285: 273: 262: 249: 235: 233: 227: 226: 222: 221: 219: 218: 205: 203: 197: 196: 194:Benzodiazepine 191: 185: 184: 179: 177:administration 171: 170: 167: 159: 158: 156: 155: 153: 143: 141: 133: 132: 129: 123: 122: 64: 60: 59: 55: 54: 46: 45: 26: 9: 6: 4: 3: 2: 10015: 10004: 10001: 9999: 9996: 9994: 9991: 9989: 9986: 9984: 9981: 9979: 9976: 9974: 9971: 9969: 9966: 9965: 9963: 9948: 9947: 9943: 9941: 9940: 9932: 9930: 9929: 9925: 9923: 9922: 9918: 9915: 9914: 9911: 9901: 9898: 9896: 9893: 9891: 9888: 9886: 9883: 9881: 9878: 9876: 9873: 9871: 9868: 9867: 9865: 9860: 9854: 9848: 9845: 9843: 9840: 9838: 9835: 9833: 9830: 9828: 9825: 9823: 9820: 9818: 9815: 9813: 9810: 9808: 9805: 9803: 9800: 9798: 9795: 9793: 9790: 9788: 9785: 9783: 9780: 9778: 9775: 9773: 9770: 9768: 9765: 9763: 9760: 9758: 9755: 9754: 9752: 9747: 9741: 9738: 9734: 9728: 9724: 9713: 9709: 9708: 9706: 9701: 9695: 9689: 9686: 9684: 9681: 9678: 9674: 9670: 9666: 9662: 9659: 9657: 9654: 9652: 9649: 9646: 9642: 9638: 9635: 9632: 9628: 9624: 9620: 9616: 9612: 9611:levomethadone 9608: 9604: 9600: 9596: 9593: 9590: 9586: 9582: 9578: 9574: 9570: 9566: 9563: 9561: 9558: 9556: 9553: 9550: 9546: 9542: 9538: 9534: 9530: 9526: 9522: 9519: 9517: 9514: 9512: 9509: 9506: 9502: 9498: 9494: 9491: 9489: 9486: 9484: 9481: 9479: 9476: 9473: 9469: 9468:flunitrazepam 9465: 9461: 9457: 9453: 9450: 9448: 9445: 9442: 9441: 9438: 9435: 9433: 9430: 9428: 9425: 9423: 9420: 9418: 9415: 9412: 9408: 9404: 9400: 9396: 9392: 9388: 9385: 9383: 9380: 9378: 9375: 9373: 9370: 9368: 9365: 9363: 9360: 9358: 9355: 9353: 9350: 9348: 9347:Isostrychnine 9345: 9343: 9340: 9338: 9335: 9333: 9330: 9328: 9325: 9323: 9320: 9317: 9313: 9309: 9306: 9304: 9301: 9299: 9296: 9294: 9291: 9289: 9286: 9284: 9281: 9279: 9276: 9274: 9271: 9269: 9266: 9264: 9261: 9259: 9256: 9254: 9251: 9249: 9246: 9244: 9241: 9238: 9237: 9234: 9231: 9229: 9226: 9223: 9219: 9215: 9211: 9207: 9203: 9199: 9195: 9191: 9187: 9183: 9179: 9175: 9171: 9168: 9165: 9161: 9157: 9153: 9149: 9145: 9141: 9138: 9136: 9133: 9131: 9128: 9126: 9123: 9121: 9118: 9116: 9113: 9111: 9110:Nitrous oxide 9108: 9105: 9101: 9097: 9093: 9089: 9085: 9082: 9080: 9077: 9075: 9072: 9070: 9067: 9064: 9060: 9056: 9053: 9051: 9048: 9045: 9041: 9038: 9036: 9033: 9031: 9028: 9025: 9021: 9020:pentobarbital 9017: 9014: 9012: 9009: 9007: 9004: 9001: 8997: 8993: 8989: 8987: 8982: 8978: 8974: 8970: 8967: 8964: 8963: 8960: 8957: 8955: 8952: 8950: 8949:Quisqualamine 8947: 8945: 8942: 8940: 8937: 8935: 8932: 8930: 8927: 8925: 8919: 8917: 8911: 8909: 8903: 8901: 8895: 8893: 8890: 8888: 8885: 8883: 8880: 8878: 8875: 8873: 8867: 8865: 8859: 8857: 8854: 8852: 8849: 8847: 8844: 8842: 8839: 8836: 8835: 8833: 8828: 8822: 8819: 8815: 8809: 8805: 8801: 8798: 8791: 8786: 8784: 8779: 8777: 8772: 8771: 8768: 8758: 8757: 8753: 8749: 8746: 8740: 8734: 8731: 8729: 8726: 8724: 8721: 8719: 8716: 8713: 8712: 8708: 8704: 8700: 8699:isovaleramide 8696: 8692: 8689: 8687: 8684: 8681: 8677: 8674: 8671: 8667: 8663: 8659: 8656: 8654: 8651: 8649: 8646: 8644: 8641: 8639: 8636: 8634: 8631: 8629: 8626: 8624: 8621: 8619: 8616: 8614: 8611: 8609: 8606: 8604: 8601: 8599: 8596: 8593: 8589: 8585: 8581: 8577: 8574: 8572: 8569: 8567: 8564: 8562: 8559: 8557: 8554: 8552: 8549: 8547: 8544: 8541: 8537: 8536:niflumic acid 8533: 8529: 8525: 8522: 8520: 8517: 8515: 8512: 8510: 8507: 8505: 8502: 8499: 8495: 8491: 8487: 8483: 8480: 8478: 8475: 8473: 8470: 8468: 8465: 8463: 8462:Clomethiazole 8460: 8458: 8457:Chlormezanone 8455: 8453: 8450: 8448: 8447:Carbamazepine 8445: 8442: 8438: 8434: 8430: 8427: 8424: 8420: 8417: 8415: 8412: 8410: 8407: 8405: 8402: 8400: 8397: 8396: 8394: 8390: 8384: 8381: 8379: 8376: 8374: 8371: 8369: 8366: 8364: 8361: 8359: 8356: 8354: 8351: 8349: 8346: 8344: 8341: 8339: 8336: 8334: 8331: 8329: 8326: 8324: 8323:Nitrous oxide 8321: 8319: 8316: 8314: 8311: 8309: 8306: 8304: 8301: 8299: 8296: 8294: 8291: 8289: 8286: 8284: 8281: 8279: 8276: 8274: 8271: 8269: 8266: 8264: 8261: 8259: 8256: 8254: 8253:Diethyl ether 8251: 8249: 8246: 8244: 8241: 8239: 8236: 8234: 8231: 8229: 8226: 8224: 8221: 8219: 8216: 8214: 8211: 8209: 8206: 8204: 8201: 8199: 8196: 8194: 8191: 8189: 8186: 8184: 8181: 8179: 8176: 8174: 8171: 8170: 8168: 8166: 8162: 8158: 8152: 8149: 8147: 8144: 8142: 8139: 8137: 8134: 8132: 8129: 8127: 8124: 8122: 8119: 8117: 8114: 8112: 8109: 8107: 8104: 8103: 8101: 8099: 8095: 8089: 8086: 8084: 8081: 8079: 8076: 8074: 8071: 8070: 8068: 8066: 8062: 8056: 8055:Pyrithyldione 8053: 8051: 8048: 8046: 8043: 8041: 8038: 8037: 8035: 8033: 8029: 8023: 8020: 8018: 8015: 8013: 8010: 8009: 8007: 8005: 8001: 7995: 7992: 7990: 7987: 7985: 7982: 7980: 7977: 7975: 7972: 7970: 7967: 7965: 7962: 7960: 7957: 7955: 7952: 7950: 7947: 7945: 7942: 7940: 7937: 7935: 7932: 7930: 7927: 7925: 7922: 7920: 7917: 7915: 7912: 7910: 7907: 7905: 7902: 7900: 7897: 7895: 7892: 7890: 7887: 7885: 7882: 7880: 7877: 7875: 7872: 7870: 7867: 7865: 7862: 7860: 7857: 7855: 7852: 7850: 7846: 7843: 7842: 7839: 7836: 7834: 7831: 7829: 7826: 7824: 7821: 7819: 7816: 7814: 7811: 7809: 7806: 7804: 7800: 7799: 7795: 7794: 7791: 7788: 7786: 7783: 7781: 7778: 7776: 7773: 7771: 7767: 7766: 7762: 7761: 7758: 7755: 7753: 7750: 7748: 7745: 7743: 7740: 7738: 7735: 7733: 7729: 7728: 7724: 7723: 7721: 7719: 7715: 7709: 7706: 7704: 7701: 7699: 7696: 7694: 7691: 7689: 7686: 7684: 7681: 7679: 7676: 7674: 7671: 7669: 7666: 7664: 7661: 7659: 7656: 7654: 7651: 7649: 7646: 7644: 7641: 7639: 7636: 7634: 7631: 7629: 7626: 7624: 7621: 7619: 7616: 7614: 7611: 7609: 7606: 7604: 7601: 7599: 7596: 7594: 7591: 7589: 7586: 7584: 7580: 7578: 7575: 7573: 7570: 7568: 7565: 7563: 7560: 7558: 7555: 7553: 7550: 7548: 7545: 7544: 7542: 7540: 7536: 7530: 7527: 7525: 7522: 7520: 7517: 7515: 7512: 7510: 7507: 7505: 7502: 7501: 7499: 7497: 7493: 7487: 7484: 7482: 7479: 7477: 7474: 7472: 7469: 7467: 7464: 7462: 7459: 7457: 7454: 7452: 7449: 7447: 7444: 7442: 7439: 7437: 7434: 7432: 7429: 7427: 7424: 7422: 7419: 7417: 7414: 7413: 7411: 7408: 7404: 7398: 7395: 7393: 7390: 7388: 7385: 7384: 7382: 7380: 7376: 7370: 7367: 7364: 7360: 7357: 7355: 7352: 7350: 7347: 7345: 7342: 7340: 7337: 7335: 7332: 7330: 7327: 7325: 7322: 7320: 7317: 7315: 7312: 7310: 7307: 7305: 7302: 7300: 7297: 7296: 7294: 7292: 7288: 7282: 7279: 7277: 7274: 7272: 7269: 7267: 7264: 7262: 7261:Phenprobamate 7259: 7257: 7254: 7252: 7249: 7247: 7244: 7242: 7239: 7237: 7234: 7232: 7229: 7227: 7226:Hexapropymate 7224: 7222: 7219: 7217: 7214: 7212: 7209: 7207: 7204: 7202: 7201:Difebarbamate 7199: 7197: 7194: 7192: 7189: 7187: 7184: 7182: 7179: 7178: 7176: 7174: 7170: 7164: 7161: 7159: 7156: 7154: 7151: 7149: 7146: 7144: 7141: 7139: 7136: 7134: 7131: 7129: 7126: 7124: 7121: 7119: 7116: 7114: 7111: 7109: 7106: 7104: 7101: 7099: 7096: 7094: 7091: 7089: 7086: 7084: 7081: 7079: 7076: 7074: 7071: 7069: 7066: 7064: 7061: 7059: 7056: 7054: 7051: 7049: 7046: 7044: 7041: 7039: 7036: 7034: 7031: 7029: 7026: 7024: 7021: 7019: 7016: 7014: 7013:Nortetrazepam 7011: 7009: 7006: 7004: 7001: 6999: 6996: 6994: 6991: 6989: 6986: 6984: 6981: 6979: 6976: 6974: 6971: 6969: 6966: 6964: 6961: 6959: 6956: 6954: 6951: 6949: 6946: 6944: 6941: 6939: 6936: 6934: 6931: 6929: 6926: 6924: 6921: 6919: 6916: 6914: 6911: 6909: 6906: 6904: 6901: 6899: 6896: 6894: 6891: 6889: 6886: 6884: 6881: 6879: 6876: 6874: 6873:Flutoprazepam 6871: 6869: 6866: 6864: 6861: 6859: 6856: 6854: 6853:Flunitrazolam 6851: 6849: 6848:Flunitrazepam 6846: 6844: 6841: 6839: 6838:Flubromazolam 6836: 6834: 6833:Flubromazepam 6831: 6829: 6826: 6824: 6821: 6819: 6816: 6814: 6811: 6809: 6806: 6804: 6801: 6799: 6796: 6794: 6791: 6789: 6786: 6784: 6781: 6779: 6776: 6774: 6771: 6769: 6766: 6764: 6761: 6759: 6756: 6754: 6751: 6749: 6746: 6744: 6741: 6739: 6736: 6734: 6733:Cloniprazepam 6731: 6729: 6726: 6724: 6721: 6719: 6716: 6714: 6711: 6709: 6706: 6704: 6701: 6699: 6696: 6694: 6691: 6689: 6686: 6684: 6681: 6679: 6676: 6674: 6671: 6669: 6666: 6664: 6661: 6659: 6656: 6654: 6651: 6649: 6646: 6644: 6641: 6639: 6636: 6634: 6631: 6629: 6626: 6624: 6623:2-Oxoquazepam 6621: 6620: 6618: 6616: 6612: 6606: 6603: 6601: 6598: 6596: 6593: 6591: 6588: 6586: 6583: 6581: 6578: 6576: 6573: 6571: 6568: 6566: 6565:Thialbarbital 6563: 6561: 6560:Tetrabarbital 6558: 6556: 6553: 6551: 6548: 6546: 6545:Spirobarbital 6543: 6541: 6538: 6536: 6533: 6531: 6528: 6526: 6525:Proxibarbital 6523: 6521: 6518: 6516: 6515:Propallylonal 6513: 6511: 6508: 6506: 6503: 6501: 6498: 6496: 6495:Phenobarbital 6493: 6491: 6488: 6486: 6485:Pentobarbital 6483: 6481: 6478: 6476: 6475:Narcobarbital 6473: 6471: 6468: 6466: 6463: 6461: 6458: 6456: 6453: 6451: 6448: 6446: 6443: 6441: 6440:Heptobarbital 6438: 6436: 6433: 6431: 6428: 6426: 6423: 6421: 6418: 6416: 6413: 6411: 6410:Difebarbamate 6408: 6406: 6403: 6401: 6400:Cyclobarbital 6398: 6396: 6393: 6391: 6388: 6386: 6383: 6381: 6378: 6376: 6373: 6371: 6368: 6366: 6363: 6361: 6358: 6356: 6353: 6351: 6348: 6346: 6345:Benzobarbital 6343: 6341: 6338: 6336: 6333: 6331: 6328: 6326: 6323: 6321: 6318: 6316: 6313: 6311: 6308: 6307: 6305: 6303: 6299: 6293: 6290: 6288: 6285: 6283: 6280: 6278: 6275: 6273: 6271: 6267: 6265: 6263: 6259: 6257: 6254: 6252: 6249: 6247: 6244: 6242: 6239: 6237: 6234: 6232: 6229: 6227: 6224: 6222: 6219: 6217: 6216:Ethchlorvynol 6214: 6211: 6207: 6204: 6202: 6199: 6197: 6194: 6192: 6189: 6187: 6184: 6183: 6181: 6179: 6175: 6171: 6158: 6153: 6151: 6146: 6144: 6139: 6138: 6135: 6123: 6120: 6118: 6115: 6113: 6110: 6108: 6105: 6103: 6100: 6097: 6093: 6090: 6088: 6085: 6081: 6080:Methocarbamol 6078: 6076: 6073: 6071: 6070:Mephenoxalone 6068: 6066: 6063: 6061: 6060:Chlorphenesin 6058: 6057: 6056: 6052: 6049: 6047: 6044: 6042: 6039: 6037: 6034: 6030: 6029:Phenaglycodol 6027: 6025: 6022: 6020: 6017: 6016: 6015: 6012: 6008: 6005: 6004: 6003: 6000: 5999: 5997: 5993: 5987: 5984: 5982: 5979: 5977: 5974: 5972: 5969: 5967: 5964: 5963: 5961: 5959: 5946: 5940: 5937: 5935: 5932: 5930: 5927: 5926: 5924: 5922: 5918: 5912: 5909: 5907: 5904: 5902: 5899: 5897: 5894: 5893: 5891: 5889: 5885: 5875: 5872: 5871: 5869: 5865: 5856: 5853: 5851: 5848: 5846: 5843: 5842: 5841: 5838: 5833: 5830: 5828: 5825: 5824: 5823: 5820: 5819: 5817: 5815: 5811: 5802: 5799: 5797: 5794: 5793: 5792: 5789: 5784: 5781: 5779: 5776: 5774: 5773:Amitriptyline 5771: 5770: 5769: 5766: 5764: 5761: 5760: 5758: 5756: 5752: 5749: 5747: 5740: 5734: 5731: 5729: 5726: 5724: 5721: 5719: 5716: 5714: 5711: 5709: 5706: 5704: 5701: 5699: 5696: 5695: 5693: 5691: 5683: 5670: 5667: 5665: 5662: 5660: 5657: 5656: 5655: 5652: 5647: 5644: 5642: 5639: 5638: 5637: 5634: 5633: 5631: 5629: 5625: 5616: 5613: 5611: 5608: 5607: 5606: 5603: 5598: 5595: 5593: 5590: 5588: 5587:Amitriptyline 5585: 5584: 5583: 5580: 5576: 5573: 5571: 5568: 5566: 5563: 5562: 5561: 5558: 5557: 5555: 5553: 5549: 5543: 5540: 5538: 5535: 5533: 5530: 5528: 5525: 5523: 5522:Methapyrilene 5520: 5518: 5515: 5513: 5510: 5508: 5505: 5503: 5500: 5498: 5495: 5494: 5492: 5490: 5486: 5483: 5481: 5474: 5468: 5465: 5463: 5460: 5458: 5455: 5453: 5450: 5447: 5443: 5440: 5438: 5435: 5433: 5430: 5428: 5427:Aceburic acid 5425: 5423: 5420: 5418: 5415: 5414: 5412: 5410: 5403: 5391: 5388: 5386: 5383: 5381: 5380:Isovaleramide 5378: 5377: 5376: 5375:Sesquiterpene 5373: 5371: 5368: 5364: 5361: 5359: 5356: 5354: 5351: 5350: 5349: 5346: 5344: 5341: 5339: 5336: 5334: 5331: 5329: 5326: 5324: 5321: 5319: 5316: 5314: 5313:Clomethiazole 5311: 5309: 5306: 5304: 5301: 5299: 5296: 5294: 5291: 5287: 5284: 5282: 5279: 5277: 5274: 5273: 5271: 5268: 5266: 5263: 5261: 5258: 5257: 5255: 5251: 5245: 5242: 5240: 5237: 5235: 5232: 5230: 5227: 5225: 5222: 5220: 5217: 5215: 5212: 5210: 5207: 5205: 5202: 5200: 5197: 5196: 5194: 5192: 5188: 5182: 5179: 5177: 5176:Pyrithyldione 5174: 5172: 5169: 5167: 5164: 5163: 5161: 5159: 5155: 5149: 5146: 5145: 5143: 5141: 5137: 5131: 5128: 5126: 5123: 5121: 5118: 5116: 5113: 5111: 5108: 5106: 5103: 5101: 5098: 5096: 5093: 5091: 5088: 5086: 5083: 5081: 5078: 5077: 5075: 5073: 5069: 5063: 5060: 5058: 5055: 5053: 5050: 5048: 5045: 5043: 5040: 5038: 5035: 5033: 5030: 5028: 5025: 5024: 5022: 5020: 5016: 5010: 5007: 5005: 5002: 5000: 4997: 4995: 4992: 4990: 4987: 4985: 4982: 4981: 4979: 4977: 4973: 4967: 4964: 4962: 4959: 4957: 4954: 4953: 4951: 4949: 4945: 4939: 4936: 4934: 4931: 4929: 4928:Phenprobamate 4926: 4924: 4923:Methocarbamol 4921: 4919: 4916: 4914: 4913:Hexapropymate 4911: 4909: 4906: 4904: 4901: 4899: 4896: 4895: 4893: 4891: 4887: 4881: 4878: 4876: 4873: 4871: 4868: 4866: 4863: 4861: 4858: 4856: 4853: 4851: 4848: 4846: 4843: 4841: 4838: 4836: 4833: 4831: 4830:Flutoprazepam 4828: 4826: 4823: 4821: 4818: 4816: 4815:Flunitrazepam 4813: 4811: 4810:Flunitrazolam 4808: 4806: 4805:Flubromazolam 4803: 4801: 4798: 4796: 4793: 4791: 4788: 4786: 4783: 4781: 4778: 4776: 4773: 4772: 4770: 4768: 4764: 4758: 4755: 4753: 4750: 4748: 4745: 4743: 4740: 4738: 4735: 4733: 4730: 4728: 4725: 4723: 4720: 4718: 4715: 4713: 4710: 4708: 4707:Phenobarbital 4705: 4703: 4700: 4698: 4697:Pentobarbital 4695: 4693: 4692:Narcobarbital 4690: 4688: 4685: 4683: 4682:Mephobarbital 4680: 4678: 4675: 4673: 4670: 4668: 4665: 4663: 4662:Cyclobarbital 4660: 4658: 4655: 4653: 4650: 4648: 4645: 4643: 4640: 4638: 4635: 4633: 4630: 4629: 4627: 4625: 4621: 4615: 4612: 4610: 4607: 4605: 4604:Ethchlorvynol 4602: 4600: 4597: 4595: 4592: 4590: 4587: 4585: 4582: 4581: 4579: 4577: 4573: 4570: 4568: 4561: 4556: 4552: 4548: 4541: 4536: 4534: 4529: 4527: 4522: 4521: 4518: 4507: 4497: 4491: 4488: 4486: 4483: 4481: 4478: 4477: 4475: 4471: 4465: 4462: 4461: 4459: 4456: 4452: 4446: 4443: 4442: 4440: 4436: 4430: 4427: 4426: 4424: 4420: 4413: 4410: 4408: 4405: 4403: 4400: 4398: 4395: 4392: 4389: 4388: 4386: 4382: 4376: 4373: 4372: 4370: 4368: 4364: 4358: 4355: 4354: 4352: 4348: 4342: 4339: 4337: 4334: 4333: 4331: 4328: 4324: 4318: 4315: 4312: 4309: 4306: 4303: 4301: 4298: 4296: 4295:Fluclotizolam 4293: 4291: 4290:Flubrotizolam 4288: 4286: 4283: 4281: 4278: 4276: 4273: 4271: 4268: 4266: 4263: 4261: 4258: 4255: 4252: 4250: 4247: 4246: 4244: 4242: 4238: 4232: 4229: 4227: 4224: 4222: 4219: 4218: 4216: 4214: 4210: 4204: 4201: 4199: 4196: 4194: 4191: 4189: 4186: 4184: 4181: 4180: 4178: 4174: 4168: 4165: 4163: 4160: 4158: 4155: 4153: 4150: 4148: 4145: 4143: 4140: 4138: 4135: 4133: 4130: 4128: 4125: 4123: 4120: 4118: 4115: 4113: 4110: 4108: 4105: 4103: 4100: 4098: 4095: 4093: 4090: 4088: 4085: 4083: 4080: 4078: 4075: 4074: 4072: 4068: 4062: 4059: 4056: 4052: 4049: 4047: 4044: 4042: 4039: 4037: 4034: 4032: 4031:Flunitrazolam 4029: 4027: 4026:Flubromazolam 4024: 4022: 4021:Flualprazolam 4019: 4017: 4016:Fluadinazolam 4014: 4012: 4009: 4007: 4004: 4002: 3999: 3996: 3993: 3991: 3988: 3986: 3983: 3982: 3980: 3978: 3974: 3968: 3965: 3963: 3960: 3958: 3955: 3953: 3950: 3948: 3945: 3943: 3940: 3939: 3937: 3933: 3927: 3924: 3922: 3919: 3917: 3914: 3912: 3909: 3907: 3904: 3903: 3901: 3897: 3891: 3888: 3886: 3883: 3881: 3878: 3876: 3873: 3870: 3867: 3864: 3861: 3859: 3856: 3854: 3851: 3849: 3846: 3844: 3841: 3839: 3836: 3834: 3831: 3829: 3826: 3824: 3821: 3818: 3815: 3813: 3810: 3807: 3804: 3802: 3799: 3797: 3794: 3792: 3789: 3787: 3784: 3782: 3779: 3777: 3774: 3772: 3769: 3767: 3764: 3762: 3759: 3757: 3756:Nortetrazepam 3754: 3752: 3749: 3747: 3744: 3742: 3739: 3737: 3734: 3732: 3729: 3727: 3724: 3722: 3720: 3716: 3714: 3711: 3709: 3706: 3704: 3701: 3699: 3696: 3694: 3691: 3688: 3685: 3683: 3680: 3678: 3675: 3673: 3670: 3668: 3665: 3662: 3659: 3657: 3654: 3652: 3649: 3647: 3644: 3642: 3639: 3637: 3636:Flutoprazepam 3634: 3632: 3629: 3627: 3624: 3622: 3621:Flunitrazepam 3619: 3617: 3614: 3612: 3609: 3607: 3606:Flubromazepam 3604: 3602: 3599: 3597: 3594: 3592: 3589: 3587: 3584: 3582: 3579: 3577: 3576:Difludiazepam 3574: 3572: 3569: 3567: 3564: 3561: 3558: 3556: 3553: 3551: 3548: 3546: 3543: 3541: 3538: 3536: 3533: 3531: 3530:Cloniprazepam 3528: 3526: 3523: 3521: 3518: 3516: 3513: 3511: 3508: 3506: 3503: 3501: 3498: 3495: 3492: 3490: 3487: 3485: 3482: 3480: 3479:2-Oxoquazepam 3477: 3476: 3474: 3470: 3466: 3459: 3454: 3452: 3447: 3445: 3440: 3439: 3436: 3430: 3427: 3425: 3422: 3421: 3402: 3398: 3392: 3383: 3375: 3371: 3365: 3357: 3353: 3347: 3339: 3335: 3329: 3313: 3307: 3291: 3287: 3281: 3273: 3269: 3263: 3255: 3251: 3247: 3243: 3236: 3220: 3216: 3210: 3202: 3198: 3192: 3184: 3180: 3174: 3158: 3154: 3150: 3144: 3133: 3129: 3122: 3116: 3100: 3096: 3089: 3081: 3075: 3067: 3065:1-59259-109-4 3061: 3057: 3053: 3049: 3045: 3038: 3030: 3026: 3020: 3004: 3000: 2993: 2985: 2981: 2977: 2973: 2969: 2965: 2961: 2957: 2950: 2942: 2938: 2934: 2930: 2923: 2915: 2911: 2907: 2903: 2899: 2895: 2888: 2880: 2876: 2872: 2868: 2864: 2860: 2856: 2852: 2845: 2829: 2823: 2815: 2811: 2807: 2803: 2799: 2795: 2791: 2787: 2780: 2772: 2768: 2764: 2760: 2753: 2745: 2739: 2735: 2731: 2724: 2709: 2705: 2701: 2697: 2693: 2689: 2685: 2678: 2670: 2666: 2662: 2658: 2654: 2650: 2643: 2635: 2631: 2627: 2623: 2619: 2612: 2604: 2600: 2595: 2590: 2586: 2582: 2578: 2571: 2563: 2559: 2555: 2551: 2544: 2529: 2525: 2518: 2516: 2507: 2500: 2492: 2488: 2484: 2480: 2476: 2472: 2465: 2457: 2453: 2449: 2445: 2441: 2437: 2434:(2): 248–60. 2433: 2429: 2422: 2414: 2408: 2404: 2400: 2393: 2391: 2389: 2387: 2385: 2383: 2381: 2372: 2368: 2364: 2360: 2356: 2352: 2345: 2337: 2333: 2329: 2325: 2318: 2310: 2306: 2300: 2298: 2296: 2287: 2280: 2273: 2271: 2262: 2258: 2253: 2248: 2244: 2240: 2236: 2232: 2224: 2216: 2212: 2208: 2204: 2200: 2196: 2189: 2181: 2177: 2173: 2169: 2165: 2161: 2154: 2146: 2142: 2138: 2134: 2130: 2126: 2122: 2118: 2111: 2109: 2100: 2096: 2092: 2088: 2084: 2080: 2076: 2072: 2065: 2057: 2053: 2049: 2045: 2041: 2037: 2030: 2022: 2018: 2014: 2010: 2006: 2002: 1995: 1987: 1983: 1979: 1973: 1971: 1969: 1960: 1956: 1952: 1948: 1944: 1940: 1936: 1932: 1925: 1917: 1913: 1909: 1905: 1901: 1897: 1894:(2): 97–103. 1893: 1889: 1882: 1874: 1870: 1866: 1862: 1858: 1854: 1850: 1846: 1839: 1823: 1819: 1813: 1811: 1802: 1798: 1793: 1788: 1783: 1778: 1774: 1770: 1767:(2): e89031. 1766: 1762: 1758: 1751: 1743: 1739: 1735: 1731: 1727: 1723: 1716: 1708: 1706:9783527607495 1702: 1698: 1697: 1689: 1678: 1674: 1667: 1661: 1659: 1657: 1655: 1639: 1635: 1629: 1627: 1610: 1606: 1602: 1598: 1592: 1584: 1580: 1574: 1570: 1569: 1561: 1557: 1550: 1538: 1534: 1529: 1525: 1521: 1517: 1513: 1509: 1505: 1501: 1498: 1494: 1490: 1486: 1483: 1479: 1478: 1473: 1466: 1463: 1460: 1457: 1453: 1450: 1447: 1445: 1440: 1437: 1434: 1430: 1429: 1428: 1426: 1422: 1412: 1403: 1401: 1397: 1392: 1388: 1386: 1381: 1375: 1365: 1356: 1354: 1350: 1346: 1342: 1338: 1334: 1330: 1326: 1321: 1319: 1314: 1310: 1306: 1305: 1290: 1282: 1268: 1265: 1260: 1258: 1257:Leo Sternbach 1254: 1244: 1241: 1239: 1235: 1231: 1227: 1224: 1214: 1212: 1208: 1203: 1200: 1195: 1193: 1188: 1186: 1183:, at various 1182: 1178: 1168: 1166: 1162: 1157: 1151: 1142: 1140: 1136: 1128: 1124: 1120: 1116: 1109: 1099: 1097: 1087: 1084: 1079: 1077: 1074: 1061: 1058: 1055: 1052: 1049: 1046: 1045: 1044: 1041: 1039: 1035: 1032: 1028: 1024: 1020: 1016: 1006: 1004: 1000: 996: 990: 980: 978: 974: 970: 966: 962: 958: 957:disinhibition 954: 950: 946: 942: 932: 930: 926: 922: 918: 914: 910: 906: 896: 894: 890: 886: 876: 874: 869: 867: 863: 854: 845: 843: 838: 836: 832: 828: 824: 820: 819:Flunitrazepam 810: 803: 794: 789: 788: 785: 778: 769: 768: 765: 758: 754: 752: 751:Melting point 748: 741: 737: 736: 734: 731: 726: 719: 717: 713: 683: 681: 677: 672: 668: 664: 661: 659: 657:ECHA InfoCard 653: 645: 641: 640:DTXSID7023065 637: 636: 634: 625: 621: 614: 610: 609: 607: 605: 601: 594: 590: 589: 587: 585: 581: 574: 570: 569: 567: 565: 561: 554: 550: 549: 547: 545: 541: 534: 530: 529: 527: 525: 521: 514: 510: 509: 507: 505: 501: 494: 490: 489: 487: 485: 481: 474: 470: 469: 467: 460: 456: 449: 445: 444: 442: 440: 436: 428: 424: 419: 418: 415: 408: 403: 400: 397: 395: 391: 387: 385: 378: 375: 371: 367: 365: 361: 358: 355: 353: 349: 343: 341: 337: 333: 329: 322: 320: 310: 308: 298: 296: 286: 283: 274: 272: 263: 260: 250: 247: 237: 236: 234: 232: 228: 223: 215: 210: 207: 206: 204: 202: 198: 195: 192: 190: 186: 183: 180: 178: 172: 168: 166: 160: 154: 145: 144: 142: 140: 134: 130: 128: 124: 118: 65: 63:Pronunciation 61: 58:Clinical data 56: 52: 47: 43: 38: 34:Flunitrazepam 30: 19: 9998:Drug culture 9944: 9933: 9926: 9919: 9645:picrotoxinin 9589:progesterone 9581:DHEA sulfate 9549:ginkgolide M 9545:ginkgolide J 9541:ginkgolide C 9537:ginkgolide B 9533:ginkgolide A 9505:nitrendipine 9467: 9443: 9240:Antagonists: 9239: 9115:Penicillin G 9059:ginsenosides 9016:Barbiturates 8985: 8965: 8846:β-ABA (BABA) 8837: 8744: 8743: 8714: 8571:Lavender oil 8313:Nitric oxide 8233:Cryofluorane 8178:Acetophenone 8136:Methaqualone 8131:Mecloqualone 8126:Mebroqualone 8116:Diproqualone 8111:Cloroqualone 8040:Glutethimide 7844: 7796: 7763: 7725: 7698:Testosterone 7663:Progesterone 7628:Hydroxydione 7577:Androsterone 7504:Acecarbromal 7409:constituents 7196:Cyclarbamate 7186:Carisoprodol 6958:Metaclazepam 6953:Menitrazepam 6943:Meclonazepam 6938:Lormetazepam 6868:Flutemazepam 6847: 6693:Ciclotizolam 6683:Carburazepam 6575:Thiobarbital 6535:Secobarbital 6500:Phetharbital 6480:Nealbarbital 6465:Methohexital 6450:Hexobarbital 6385:Butallylonal 6380:Butobarbital 6335:Barbexaclone 6330:Aprobarbital 6315:Allobarbital 6302:Barbiturates 6269: 6261: 6251:Petrichloral 6122:Valnoctamide 6024:Metaglycodol 6019:Fenpentadiol 5929:Daridorexant 5832:Thioridazine 5783:Trimipramine 5718:Medetomidine 5646:Thioridazine 5597:Trimipramine 5542:Propiomazine 5537:Promethazine 5343:Petrichloral 5328:Kavalactones 5260:Acetophenone 5229:Methaqualone 5224:Mecloqualone 5219:Mebroqualone 5209:Diproqualone 5204:Cloroqualone 5166:Glutethimide 5062:Progesterone 5052:Hydroxydione 4984:Acecarbromal 4898:Carisoprodol 4840:Lormetazepam 4825:Flutemazepam 4814: 4727:Secobarbital 4687:Methohexital 4677:Hexobarbital 4657:Butobarbital 4652:Butabarbital 4642:Aprobarbital 4632:Allobarbital 4624:Barbiturates 4265:Ciclotizolam 3718: 3708:Metaclazepam 3703:Menitrazepam 3693:Meclonazepam 3682:Lormetazepam 3631:Flutemazepam 3620: 3505:Carburazepam 3404:. Retrieved 3400: 3391: 3382: 3373: 3364: 3355: 3346: 3337: 3328: 3318:February 17, 3316:. Retrieved 3306: 3296:February 27, 3294:. Retrieved 3289: 3280: 3271: 3262: 3245: 3241: 3235: 3223:. Retrieved 3218: 3209: 3200: 3191: 3182: 3173: 3161:. Retrieved 3157:the original 3152: 3143: 3132:the original 3127: 3115: 3103:. Retrieved 3099:The Guardian 3098: 3088: 3047: 3037: 3028: 3019: 3007:. Retrieved 3003:the original 2992: 2959: 2955: 2949: 2932: 2928: 2922: 2897: 2893: 2887: 2854: 2850: 2844: 2832:. Retrieved 2822: 2789: 2785: 2779: 2771:the original 2766: 2762: 2752: 2729: 2723: 2713:November 15, 2711:. Retrieved 2691: 2687: 2677: 2652: 2648: 2642: 2625: 2621: 2611: 2584: 2580: 2570: 2553: 2549: 2543: 2533:November 15, 2531:. Retrieved 2527: 2505: 2499: 2474: 2470: 2464: 2431: 2427: 2421: 2402: 2354: 2350: 2344: 2327: 2323: 2317: 2308: 2285: 2234: 2230: 2223: 2198: 2194: 2188: 2163: 2159: 2153: 2120: 2116: 2074: 2070: 2064: 2039: 2035: 2029: 2004: 2000: 1994: 1986:the original 1981: 1934: 1930: 1924: 1891: 1887: 1881: 1848: 1844: 1838: 1826:. Retrieved 1822:the original 1764: 1760: 1750: 1725: 1721: 1715: 1695: 1688: 1672: 1641:. Retrieved 1637: 1613:. Retrieved 1591: 1567: 1560: 1547: 1508:illegal drug 1442: 1421:Schedule III 1418: 1415:Regional use 1409: 1393: 1389: 1377: 1362: 1339:(as well as 1322: 1302: 1300: 1261: 1250: 1242: 1225: 1220: 1204: 1196: 1189: 1174: 1171:Pharmacology 1155: 1152: 1148: 1111: 1093: 1090:Interactions 1080: 1070: 1042: 1012: 992: 938: 902: 882: 870: 859: 839: 822: 818: 817: 806:   426: 422: 381:Elimination 231:Legal status 225:Legal status 29: 9842:SSR-504,734 9837:SSR-103,800 9827:PF-03463275 9807:Mardepodect 9727:Transporter 9673:tropisetron 9615:levorphanol 9607:dextrorphan 9529:ginkgolides 9497:nicardipine 9352:Laudanosine 9273:Cacotheline 9263:Bicuculline 9210:sevoflurane 9160:tropisetron 9044:nicardipine 8887:Hypotaurine 8653:Stiripentol 8648:Seproxetine 8618:Niacinamide 8598:Loreclezole 8419:Avermectins 8383:Vinyl ether 8353:Sevoflurane 8333:Paraldehyde 8283:Halopropane 8106:Afloqualone 8088:Tracazolate 8083:ICI-190,622 8073:Cartazolate 8050:Piperidione 8045:Methyprylon 8012:Fospropofol 7934:Pipequaline 7742:Pazinaclone 7732:Eszopiclone 7588:Cholesterol 7572:Androstenol 7496:Monoureides 7476:Methysticin 7276:Tetrabamate 7256:Pentabamate 7246:Meprobamate 7216:Febarbamate 7181:Carisbamate 7133:Triflubazam 7123:Tolufazepam 7083:Rilmazafone 7078:Remimazolam 7053:Proflazepam 7038:Pivoxazepam 6998:Nitrazepate 6988:Nimetazepam 6923:Lopirazepam 6893:Haloxazolam 6843:Fludiazepam 6788:Doxefazepam 6763:Delorazepam 6743:Clotiazepam 6738:Clorazepate 6703:Cinolazepam 6600:Vinbarbital 6555:Tetrabamate 6510:Probarbital 6490:Phenallymal 6455:Metharbital 6430:Febarbamate 6325:Amobarbital 6226:Isopropanol 6196:Chloralodol 6107:Scopolamine 6051:Guaifenesin 6046:Fenadiazole 6002:Cannabidiol 5976:Mirogabalin 5934:Lemborexant 5911:Tasimelteon 5896:Agomelatine 5855:Risperidone 5801:Mirtazapine 5690:-Adrenergic 5669:Risperidone 5615:Mirtazapine 5565:Etoperidone 5532:Pheniramine 5517:Hydroxyzine 5338:Paraldehyde 5333:Loreclezole 5199:Afloqualone 5181:Piperidione 5171:Methyprylon 5100:Pazinaclone 5080:Eszopiclone 5042:Alphaxolone 5037:Alphadolone 4976:Monoureides 4918:Meprobamate 4855:Nitemazepam 4850:Nimetazepam 4795:Doxefazepam 4780:Cinolazepam 4752:Vinbarbital 4717:Proxibarbal 4702:Phenallymal 4637:Amobarbital 4589:Chloralodol 4490:Rilmazafone 4464:Anthramycin 4357:Lopirazepam 4341:Telenzepine 4300:Fluetizolam 4226:Clotiazepam 4193:Haloxazolam 4137:Remimazolam 4112:I-Iomazenil 4055:Rilmazafone 3926:Triflubazam 3875:Tolufazepam 3786:Proflazepam 3776:Pivoxazepam 3746:Nitrazepate 3736:Nitemazepam 3731:Nimetazepam 3616:Fludiazepam 3581:Doxefazepam 3545:Delorazepam 3535:Clorazepate 3520:Cinolazepam 3406:October 18, 3225:January 24, 3183:Gelbe Liste 2900:(1): 7–10. 2564:. rohypnol. 2252:10852/34650 1512:Schedule IV 1234:nimetazepam 1223:fluorinated 1137:antagonist 1098:and death. 1027:psychomotor 969:convulsions 723: g·mol 663:100.015.089 613:ChEMBL13280 593:CHEBI:31622 405:Identifiers 388:18–26 hours 364:Metabolites 127:Trade names 9962:Categories 9847:Tilapertin 9802:LY-2365109 9797:Iclepertin 9792:GSK1018921 9677:zatosetron 9665:bemesetron 9637:Picrotoxin 9555:Imipramine 9525:bilobalide 9511:Furosemide 9501:nifedipine 9472:flurazepam 9460:clonazepam 9456:bromazepam 9427:Strychnine 9422:Sinomenine 9387:Quinolines 9377:Pitrazepin 9298:Dendrobine 9283:Colchicine 9202:isoflurane 9186:desflurane 9182:chloroform 9164:zatosetron 9148:bemesetron 9100:minaxolone 9088:alfaxolone 9074:Ivermectin 9011:Anandamide 8934:Milacemide 8924:-Threonine 8892:Ivermectin 8800:modulators 8686:Topiramate 8676:Terpenoids 8633:Propanidid 8623:Org 25,435 8551:Flupirtine 8546:Fluoxetine 8452:Chloralose 8423:ivermectin 8328:Norflurane 8293:Isoflurane 8238:Desflurane 8228:Chloroform 8188:Aliflurane 8121:Etaqualone 7949:SB-205,384 7879:CP-615,003 7874:CL-218,872 7828:Panadiplon 7818:Lorediplon 7747:Suproclone 7708:Zuranolone 7668:Renanolone 7653:Posovolone 7633:Minaxolone 7623:Ganaxolone 7562:Alfaxalone 7557:Alfadolone 7547:Acebrochol 7514:Bromisoval 7392:Metomidate 7379:Imidazoles 7339:Hispidulin 7291:Flavonoids 7251:Nisobamate 7241:Mebutamate 7211:Ethinamate 7206:Emylcamate 7173:Carbamates 7143:Tuclazepam 7118:Tetrazepam 7073:Reclazepam 7048:Premazepam 7028:Phenazepam 7008:Nordazepam 7003:Nitrazolam 6993:Nitrazepam 6973:Motrazepam 6928:Loprazolam 6918:Lofendazam 6903:Imidazenil 6863:Flutazolam 6858:Flurazepam 6828:Fletazepam 6783:Dimdazenil 6778:Diclazepam 6758:Cyprazepam 6748:Cloxazolam 6728:Clonazolam 6723:Clonazepam 6713:Climazolam 6673:Brotizolam 6668:Bromazolam 6663:Bromazepam 6658:Bretazenil 6653:Bentazepam 6643:Arfendazam 6638:Alprazolam 6633:Adinazolam 6605:Vinylbital 6585:Thiopental 6460:Methitural 6375:Buthalital 6370:Butalbital 6221:Isobutanol 6075:Metaxalone 6065:Mephenesin 5986:Pregabalin 5966:Gabapentin 5939:Suvorexant 5874:Niaprazine 5850:Quetiapine 5845:Olanzapine 5728:Tizanidine 5723:Romifidine 5713:Lofexidine 5703:Detomidine 5664:Quetiapine 5659:Olanzapine 5570:Nefazodone 5512:Doxylamine 5497:Captodiame 5308:Chloralose 5272:compounds 5214:Etaqualone 5110:Suproclone 5090:Lirequinil 5057:Minaxolone 5047:Eltanolone 5027:Acebrochol 4994:Bromisoval 4961:Metomidate 4948:Imidazoles 4908:Ethinamate 4903:Emylcamate 4890:Carbamates 4865:Nitrazolam 4860:Nitrazepam 4835:Loprazolam 4820:Flurazepam 4790:Clonazolam 4785:Climazolam 4775:Brotizolam 4757:Vinylbital 4742:Thiopental 4429:Premazepam 4412:Zometapine 4336:Olanzapine 4305:Israpafant 4270:Clotizolam 4260:Brotizolam 4221:Bentazepam 4188:Flutazolam 4183:Cloxazolam 4162:Sarmazenil 4122:Loprazolam 4107:Imidazenil 4097:Flumazenil 4082:Climazolam 4077:Bretazenil 4051:Rilmazolam 4041:Phenazolam 4036:Nitrazolam 4006:Clonazolam 4001:Bromazolam 3995:Balovaptan 3990:Alprazolam 3985:Adinazolam 3962:Talampanel 3952:GYKI-52895 3947:GYKI-52466 3921:Lofendazam 3906:Arfendazam 3885:Tuclazepam 3858:Tetrazepam 3801:Reclazepam 3766:Phenazepam 3751:Nordazepam 3741:Nitrazepam 3713:Motrazepam 3667:Kenazepine 3626:Flurazepam 3611:Fletazepam 3571:Diclazepam 3560:Devazepide 3540:Cyprazepam 3525:Clonazepam 3494:BMS-906024 3489:Bromazepam 3397:"Rohypnol" 3334:"Substans" 3268:"Rohypnol" 3128:Green List 2528:Tripsitter 2477:(1): 5–8. 2357:(1): 1–6. 1615:August 16, 1553:References 1533:US Customs 1528:§ 952 1520:§ 841 1493:Schedule 3 1444:Anlage III 1433:Schedule 8 1331:) such as 1325:anxiolytic 1313:Nitrazepam 1238:clonazepam 1230:nitrazepam 1139:flumazenil 1106:See also: 995:lipophilic 987:See also: 959:, loss of 899:Dependence 885:somnolence 835:anesthesia 728:3D model ( 716:Molar mass 553:620X0222FQ 524:ChemSpider 484:IUPHAR/BPS 439:CAS Number 414:IUPAC name 352:Metabolism 282:Anlage III 271:Schedule I 189:Drug class 9895:ORG-25543 9875:Amoxapine 9832:Sarcosine 9812:ORG-24598 9777:CP-802079 9683:Verapamil 9669:LY-278584 9661:Tropeines 9627:pethidine 9623:oripavine 9516:Genistein 9447:Amiloride 9327:Gelsemine 9303:Diaboline 9288:Colubrine 9198:halothane 9194:enflurane 9170:Volatiles 9156:LY-278584 9140:Tropeines 9135:Triclofos 9125:Tamoxifen 9104:ORG-20599 9050:Etomidate 8973:brometone 8954:Sarcosine 8929:MDL-27531 8841:β-Alanine 8838:Agonists: 8745:See also: 8707:valerenol 8628:Phenytoin 8608:Monastrol 8566:Lanthanum 8561:KRM-II-81 8524:Fenamates 8519:Etifoxine 8514:Etazepine 8509:Efavirenz 8467:Darigabat 8363:Teflurane 8348:Roflurane 8343:Propylene 8288:Halothane 8273:Fluroxene 8258:Enflurane 8161:Volatiles 8078:Etazolate 7989:Viqualine 7944:RWJ-51204 7909:L-838,417 7899:Imepitoin 7869:CGS-20625 7864:CGS-13767 7849:Adipiplon 7823:Ocinaplon 7785:Saripidem 7780:Necopidem 7757:Zopiclone 7752:Suriclone 7737:Pagoclone 7643:ORG-21465 7638:ORG-20599 7529:Ectylurea 7519:Carbromal 7397:Propoxate 7387:Etomidate 7314:Baicalein 7271:Styramate 7266:Procymate 7236:Lorbamate 7221:Felbamate 7191:Clocental 7163:Zomebazam 7158:Zolazepam 7153:Zapizolam 7148:Uldazepam 7128:Triazolam 7113:Temazepam 7108:Sulazepam 7098:Ro48-8684 7093:Ro48-6791 7088:Ripazepam 7058:Pyrazolam 7033:Pinazepam 6983:Nifoxipam 6968:Midazolam 6963:Mexazolam 6948:Medazepam 6933:Lorazepam 6913:Ketazolam 6908:Irazepine 6898:Iclazepam 6888:Halazepam 6883:Gidazepam 6878:Fosazepam 6798:Estazolam 6793:Elfazepam 6768:Demoxepam 6698:Cinazepam 6678:Camazepam 6648:Avizafone 6570:Thiamylal 6505:Primidone 6435:Heptabarb 6425:Eterobarb 6390:Carbubarb 6287:Triclofos 6186:Brometone 6112:Trazodone 6053:-related 5906:Ramelteon 5901:Melatonin 5888:Melatonin 5796:Mianserin 5763:Trazodone 5698:Clonidine 5610:Mianserin 5575:Trazodone 5527:Perlapine 5370:Triclofos 5323:Gaboxadol 5130:Zopiclone 5115:Suriclone 5105:Saripidem 5095:Necopidem 5009:Ectylurea 5004:Carbromal 4966:Propoxate 4956:Etomidate 4933:Procymate 4880:Triazolam 4875:Temazepam 4845:Midazolam 4800:Estazolam 4737:Thiamylal 4672:Heptabarb 4551:sedatives 4547:Hypnotics 4485:Avizafone 4407:Zomebazam 4402:Zolazepam 4397:Ripazepam 4391:Razobazam 4375:Zapizolam 4317:Metizolam 4231:Ro09-9212 4198:Mexazolam 4157:Ro4938581 4152:Ro48-8684 4147:Ro48-6791 4142:Ro15-4513 4127:Midazolam 4117:L-655,708 4061:Triazolam 4046:Pyrazolam 4011:Estazolam 3967:Tofisopam 3957:Nerisopam 3942:Girisopam 3890:Uldazepam 3869:Timelotem 3863:Tifluadom 3853:Temazepam 3848:Sulazepam 3843:SH-I-048A 3838:Ro20-8552 3833:Ro20-8065 3828:Ro07-9749 3823:Ro07-5220 3812:Ro05-4082 3806:RO4491533 3771:Pinazepam 3726:Nifoxipam 3698:Medazepam 3687:Lufuradom 3677:Lorazepam 3672:Ketazolam 3661:Irazepine 3656:Iclazepam 3651:Halazepam 3646:Gidazepam 3641:Fosazepam 3586:Elfazepam 3550:Demoxepam 3515:Cinazepam 3500:Camazepam 3356:Janusinfo 3163:March 13, 3074:cite book 3029:Expressen 2117:CNS Drugs 1643:April 13, 1638:Drugs.com 1435:medicine. 1427:of 1971. 1400:temazepam 1396:midazolam 1337:zopiclone 1264:date rape 1217:Chemistry 1199:half-life 1145:Detection 1015:confusion 1003:hypotonia 989:Hypotonia 983:Hypotonia 953:confusion 949:agitation 921:psychosis 893:hypotonia 448:1622-62-4 394:Excretion 383:half-life 175:Routes of 165:liability 163:Addiction 137:Pregnancy 9916:See also 9870:ALX-1393 9733:blockers 9714:instead. 9656:Riluzole 9641:picrotin 9631:thebaine 9619:morphine 9488:Daidzein 9478:Corymine 9464:diazepam 9399:5,7-CIQA 9332:iso-THAZ 9278:Caffeine 9144:atropine 9120:Propofol 9079:Ketamine 8969:Alcohols 8944:Propofol 8908:-Proline 8900:-Alanine 8864:-Alanine 8808:Receptor 8733:TCS-1205 8728:TCS-1105 8718:α-Pinene 8691:Valerian 8666:tetronal 8643:Safranal 8592:obovatol 8588:magnolol 8584:honokiol 8414:Alogabat 8409:AA-29504 8358:Synthane 8318:Nitrogen 8298:Kerosine 8278:Gasoline 8268:Ethylene 8208:Centalun 8203:Butylene 8017:Propofol 7979:U-89843A 7959:TGSC01AA 7929:NS-11394 7894:GBLD-345 7859:CGS-9896 7854:CGS-8216 7838:Zaleplon 7833:Taniplon 7813:Indiplon 7808:Fasiplon 7803:Divaplon 7790:Zolpidem 7693:SAGE-872 7688:SAGE-689 7683:SAGE-516 7678:SAGE-324 7673:SAGE-105 7581:Certain 7524:Capuride 7486:Yangonin 7363:baicalin 7359:Skullcap 7349:Luteolin 7324:Catechin 7319:Baicalin 7309:Apigenin 7281:Tybamate 7068:Quazepam 7063:QH-II-66 7043:Prazepam 7023:Oxazolam 7018:Oxazepam 6818:Etizolam 6773:Diazepam 6753:CP-1414S 6718:Clobazam 6708:Clazolam 6595:Valofane 6550:Talbutal 6540:Sigmodal 6445:Hexethal 6340:Barbital 6320:Alphenal 6310:(-)-DMBB 6256:Propanol 6246:Pentanol 6236:Methanol 6178:Alcohols 6096:morphine 6087:Midaflur 6007:Cannabis 5981:Phenibut 5733:Xylazine 5462:Phenibut 5432:Baclofen 5358:Tetronal 5293:Centalun 5148:Propofol 5125:Zolpidem 5120:Zaleplon 5085:Indiplon 4999:Capuride 4938:Tybamate 4870:Quazepam 4732:Talbutal 4647:Barbital 4576:Alcohols 4508:ligands) 4506:receptor 4445:Clazolam 4285:Etizolam 4203:Oxazolam 4102:GL-II-73 3916:CP-1414S 3911:Clobazam 3817:Ro5-4864 3796:QH-II-66 3791:Quazepam 3781:Prazepam 3761:Oxazepam 3566:Diazepam 3254:16505866 3101:. London 2984:28937806 2914:10641912 2879:25511804 2871:17417081 2834:June 30, 2830:. EMCDDA 2814:19770310 2708:14185980 2634:11159802 2603:23789008 2456:25511804 2448:17417081 2371:11955823 2336:12474705 2324:Medicina 2261:18226959 2215:19900604 2180:20171127 2145:25592318 2137:15089115 2099:27014006 2056:16087304 1959:24102880 1951:12850977 1916:46172276 1873:25151953 1828:June 13, 1801:24586489 1761:PLOS ONE 1742:10881768 1677:Archived 1609:Archived 1583:Archived 1333:zolpidem 1329:hypnotic 1292:Rohypnol 1156:in vitro 1135:receptor 1121:such as 1102:Overdose 1096:toxicity 1073:comorbid 1056:Vomiting 1034:hypnotic 1023:hangover 999:placenta 917:seizures 889:overdose 873:ketamine 831:insomnia 823:Rohypnol 809:(verify) 504:DrugBank 259:Class B1 201:ATC code 139:category 131:Rohypnol 18:Rohypnol 9983:Lactams 9900:VVZ-368 9767:ASP2535 9663:(e.g., 9639:(i.e., 9599:codeine 9597:(e.g., 9595:Opioids 9567:(e.g., 9531:(e.g., 9495:(e.g., 9454:(e.g., 9417:RU-5135 9389:(e.g., 9310:(e.g., 9268:Brucine 9214:toluene 9176:(e.g., 9152:cocaine 9142:(e.g., 9086:(e.g., 9061:(e.g., 9055:Ginseng 9042:(e.g., 9035:D12-116 9018:(e.g., 8971:(e.g., 8959:Taurine 8916:-Serine 8882:Glycine 8872:-Serine 8856:Caesium 8814:ligands 8680:borneol 8678:(e.g., 8670:trional 8660:(e.g., 8578:(e.g., 8576:Lignans 8526:(e.g., 8484:(e.g., 8429:Bromide 8421:(e.g., 8404:α-EMTBL 8368:Toluene 8338:Propane 8213:Chloral 8193:Benzene 8173:Acetone 8004:Phenols 7994:Y-23684 7984:U-90042 7969:TPA-023 7954:SX-3228 7939:ROD-188 7924:NS-2710 7919:NS-2664 7904:JM-1232 7889:ELB-139 7884:CTP-354 7770:Alpidem 7369:Wogonin 7344:Linarin 6823:FG-8205 6530:Reposal 6231:Menthol 6191:Butanol 6094:(e.g., 6092:Opioids 6041:Evoxine 5778:Doxepin 5592:Doxepin 5467:Tolibut 5363:Trional 5270:Bromide 5140:Phenols 4722:Reposal 4254:Apafant 4132:PWZ-029 4092:FG-8205 4087:EVT-201 3203:. 1993. 3009:May 19, 2976:8311057 2941:8231567 2806:2776820 2669:7782744 2594:3684331 2491:9456517 2091:6124415 1865:6108205 1792:3929633 1769:Bibcode 1497:Class C 1359:Suicide 1318:Finland 1247:History 1127:opioids 1123:ethanol 1038:alcohol 965:violent 925:anxiety 721:313.288 680:Formula 513:DB01544 459:PubChem 295:Class C 280:: 269:: 217:) 211: ( 209:N05CD03 152: C 9521:Ginkgo 9411:7-TFQA 9258:αEMBTL 8851:β-AIBA 8613:Niacin 8198:Butane 8151:SL-164 8022:Thymol 7964:TP-003 7845:Others 7648:P1-185 7608:5β-DHP 7603:5α-DHP 7598:3α-DHP 7446:Kavain 7354:Rc-OMe 5995:Others 5921:Orexin 5867:Others 5857:, etc. 5834:, etc. 5803:, etc. 5785:, etc. 5671:, etc. 5648:, etc. 5617:, etc. 5599:, etc. 5253:Others 5244:SL-164 3374:Gov.uk 3252:  3105:May 2, 3062:  2982:  2974:  2939:  2912:  2877:  2869:  2812:  2804:  2740:  2706:  2667:  2632:  2601:  2591:  2560:  2489:  2454:  2446:  2409:  2369:  2334:  2259:  2213:  2178:  2143:  2135:  2097:  2089:  2054:  2021:430730 2019:  1957:  1949:  1914:  1906:  1871:  1863:  1799:  1789:  1740:  1703:  1597:Anvisa 1575:  1526:  1518:  1456:Chugai 1347:, and 1309:Sweden 1207:CYP3A4 887:; and 764:SMILES 604:ChEMBL 573:D01230 399:Kidney 317: 305: 293: 257: 244: 121: 9885:NAGly 9858:GlyT2 9757:ACPPB 9745:GlyT1 9699:NMDAR 9437:Tutin 9407:7-TFQ 9403:7-CIQ 9228:Xenon 9174:gases 8472:DEABL 8165:gases 7974:TP-13 7703:THDOC 7593:DHDOC 6117:UMB68 5437:GABOB 3135:(PDF) 3124:(PDF) 2980:S2CID 2875:S2CID 2810:S2CID 2562:23801 2452:S2CID 2282:(PDF) 2141:S2CID 2095:S2CID 2071:Drugs 1955:S2CID 1912:S2CID 1869:S2CID 1845:Drugs 1680:(PDF) 1669:(PDF) 1544:Names 1488:2020. 1482:Mylan 1253:Roche 1179:, an 1009:Other 784:InChI 730:JSmol 584:ChEBI 429:)-one 357:Liver 9935:GABA 9712:here 9710:See 9688:Zinc 9651:PMBA 9643:and 9560:NBQX 9312:2-AG 9233:Zinc 8986:tert 8877:GABA 8826:GlyR 7775:DS-1 7407:Kava 7334:EGCG 6270:tert 6262:tert 6165:GABA 5957:VDCC 5743:5-HT 5406:GABA 4584:2M2B 4564:GABA 4555:N05C 4502:GABA 3408:2020 3386:DEA 3320:2022 3298:2020 3250:PMID 3227:2021 3165:2006 3107:2010 3080:link 3060:ISBN 3011:2006 2972:PMID 2937:PMID 2910:PMID 2867:PMID 2836:2022 2802:PMID 2738:ISBN 2715:2023 2704:PMID 2665:PMID 2630:PMID 2599:PMID 2558:PMID 2535:2023 2487:PMID 2444:PMID 2407:ISBN 2367:PMID 2332:PMID 2257:PMID 2211:PMID 2176:PMID 2133:PMID 2087:PMID 2052:PMID 2017:PMID 2001:JAMA 1947:PMID 1908:7095 1904:PMID 1861:PMID 1830:2016 1797:PMID 1738:PMID 1701:ISBN 1645:2016 1617:2023 1573:ISBN 1522:and 1495:and 1398:and 1335:and 1177:GABA 1163:and 1131:GABA 1017:and 564:KEGG 544:UNII 533:3263 493:4193 473:3380 372:and 334:data 182:Oral 169:High 8504:DS2 7613:DHT 7329:EGC 5457:GVL 5452:GBL 5442:GHB 4311:JQ1 3246:126 3052:doi 2964:doi 2902:doi 2859:doi 2794:doi 2767:283 2734:537 2696:doi 2657:doi 2589:PMC 2479:doi 2436:doi 2359:doi 2355:126 2247:hdl 2239:doi 2203:doi 2168:doi 2125:doi 2079:doi 2044:doi 2040:159 2009:doi 2005:241 1939:doi 1896:doi 1853:doi 1787:PMC 1777:doi 1730:doi 1327:or 848:Use 629:EPA 463:CID 214:WHO 9964:: 9675:, 9671:, 9667:, 9629:, 9625:, 9621:, 9617:, 9613:, 9609:, 9605:, 9601:, 9587:, 9583:, 9579:, 9575:, 9571:, 9551:)) 9547:, 9543:, 9539:, 9535:, 9527:, 9503:, 9499:, 9470:, 9466:, 9462:, 9458:, 9409:, 9405:, 9401:, 9397:, 9393:, 9314:, 9220:, 9216:, 9212:, 9208:, 9204:, 9200:, 9196:, 9192:, 9188:, 9184:, 9180:, 9162:, 9158:, 9154:, 9150:, 9146:, 9102:, 9098:, 9094:, 9090:, 9065:)) 9022:, 8998:, 8994:, 8990:, 8983:, 8979:, 8975:, 8754:• 8750:• 8705:, 8701:, 8697:, 8668:, 8664:, 8590:, 8586:, 8582:, 8538:, 8534:, 8530:, 8496:, 8492:, 8488:, 8439:, 8435:, 7847:: 7801:: 7768:: 7730:: 5745:2A 3399:. 3372:. 3336:. 3288:. 3270:. 3244:. 3217:. 3199:. 3181:. 3151:. 3126:. 3097:. 3076:}} 3072:{{ 3046:. 3027:. 2978:. 2970:. 2960:14 2958:. 2933:90 2931:. 2908:. 2898:45 2896:. 2873:. 2865:. 2855:29 2853:. 2808:. 2800:. 2790:36 2788:. 2765:. 2761:. 2736:. 2702:. 2690:. 2686:. 2663:. 2653:40 2651:. 2626:29 2624:. 2620:. 2597:. 2585:13 2583:. 2579:. 2554:27 2552:. 2526:. 2514:^ 2485:. 2475:43 2473:. 2450:. 2442:. 2432:29 2430:. 2379:^ 2365:. 2353:. 2328:38 2326:. 2307:. 2294:^ 2284:. 2269:^ 2255:. 2245:. 2233:. 2209:. 2199:67 2197:. 2174:. 2164:14 2162:. 2139:. 2131:. 2121:18 2119:. 2107:^ 2093:. 2085:. 2075:23 2073:. 2050:. 2038:. 2015:. 2003:. 1980:. 1967:^ 1953:. 1945:. 1935:31 1933:. 1910:. 1902:. 1892:20 1890:. 1867:. 1859:. 1849:20 1847:. 1809:^ 1795:. 1785:. 1775:. 1763:. 1759:. 1736:. 1726:93 1724:. 1671:. 1653:^ 1636:. 1625:^ 1581:. 1514:. 1343:, 1167:. 1078:. 979:. 971:. 955:, 951:, 947:, 927:. 919:, 844:. 694:12 688:16 313:UN 301:US 289:UK 277:DE 266:CA 253:BR 246:S8 240:AU 148:AU 81:uː 9937:A 9735:) 9731:( 9679:) 9647:) 9633:) 9591:) 9507:) 9474:) 9413:) 9318:) 9224:) 9172:/ 9166:) 9106:) 9046:) 9026:) 9002:) 8922:L 8914:L 8906:L 8898:L 8870:D 8862:D 8816:) 8812:( 8789:e 8782:t 8775:v 8709:) 8682:) 8672:) 8594:) 8542:) 8500:) 8443:) 8425:) 8163:/ 7365:) 6212:) 6208:( 6168:A 6156:e 6149:t 6142:v 6098:) 5954:δ 5952:2 5950:α 5688:2 5686:α 5479:1 5477:H 5448:) 5444:( 5408:B 4566:A 4557:) 4553:( 4549:/ 4539:e 4532:t 4525:v 4504:A 4457:* 4414:* 4393:* 4329:* 4313:* 4307:* 4256:* 4057:) 3997:* 3871:* 3865:* 3819:* 3808:* 3719:N 3689:* 3663:* 3562:* 3496:* 3457:e 3450:t 3443:v 3410:. 3340:. 3322:. 3300:. 3256:. 3229:. 3167:. 3109:. 3082:) 3068:. 3054:: 3031:. 3013:. 2986:. 2966:: 2943:. 2916:. 2904:: 2881:. 2861:: 2838:. 2816:. 2796:: 2746:. 2717:. 2698:: 2692:6 2671:. 2659:: 2636:. 2605:. 2537:. 2493:. 2481:: 2458:. 2438:: 2415:. 2373:. 2361:: 2338:. 2263:. 2249:: 2241:: 2235:9 2217:. 2205:: 2182:. 2170:: 2147:. 2127:: 2101:. 2081:: 2058:. 2046:: 2023:. 2011:: 1961:. 1941:: 1918:. 1898:: 1875:. 1855:: 1832:. 1803:. 1779:: 1771:: 1765:9 1744:. 1732:: 1709:. 1647:. 1619:. 1499:. 1226:N 1133:A 732:) 709:3 706:O 703:3 700:N 697:F 691:H 685:C 631:) 627:( 427:H 423:H 315:: 303:: 291:: 255:: 242:: 150:: 117:/ 114:m 111:æ 108:p 105:ɪ 102:z 99:æ 96:r 93:t 90:ˈ 87:ɪ 84:n 78:l 75:f 72:ˌ 69:/ 20:)

Index

Rohypnol


/ˌflnɪˈtræzɪpæm/
Trade names
Pregnancy
category

Addiction
liability

Routes of
administration

Oral
Drug class
Benzodiazepine
ATC code
N05CD03
WHO
Legal status
S8
Class B1
Schedule I
Anlage III
Class C
Schedule IV (Schedule I trafficking penalties, however)
Psychotropic Schedule III
Pharmacokinetic
Bioavailability
Metabolism
Liver
Metabolites
desmethylflunitrazepam
3-hydroxydesmethylflunitrazepam
Elimination half-life

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