1003:
94:
during initiation of transcription. This region of the DNA is also the first place where base pairs separate during prokaryotic transcription to allow access to the template strand. The AT-richness is important to allow this separation, since
67:—that is, it shows the most frequently occurring base at each position in many promoters analyzed; individual promoters often vary from the consensus at one or more positions. It is also commonly called the
119:
305:
233:
115:
108:
1044:
560:
706:
938:
910:
963:
905:
1063:
958:
926:
900:
1037:
553:
586:
75:, because it is centered roughly ten base pairs upstream from the site of initiation of transcription.
783:
719:
689:
667:
577:
569:
56:
1068:
884:
573:
370:"Structural Basis for Promoter −10 Element Recognition by the Bacterial RNA Polymerase σ Subunit"
187:
1030:
793:
546:
489:
423:
977:
972:
840:
742:
419:"Base-stacking and base-pairing contributions into thermal stability of the DNA double helix"
874:
788:
754:
648:
314:
242:
8:
857:
825:
711:
685:
538:
318:
301:"Nucleotide sequence of an RNA polymerase binding site from the DNA of Bacteriophage fd"
246:
626:
453:
418:
394:
369:
192:
64:
48:
519:
477:
417:
Yakovchuk, Peter; Protozanova, Ekaterina; Frank-Kamenetskii, Maxim D. (January 2006).
345:
300:
273:
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1018:
945:
524:
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458:
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332:
278:
260:
867:
850:
514:
498:
448:
432:
389:
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340:
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268:
250:
731:
1014:
941:
929:
879:
385:
229:"Nucleotide sequence of an RNA polymerase binding site at an early T7 promoter"
91:
1057:
643:
510:
444:
336:
264:
104:
502:
462:
403:
528:
354:
327:
282:
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125:
798:
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436:
982:
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631:
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32:
638:
416:
83:
299:
Schaller, Heinz; Gray, Christopher; Herrman, Karin (February 1975).
1010:
845:
835:
204:
79:
60:
1002:
805:
672:
100:
96:
87:
44:
40:
36:
601:
16:
DNA sequence required in bacterial promoters for transcription
862:
714:
933:
763:
694:
568:
52:
476:
Harley, Calvin B.; Reynolds, Robert P. (March 1987).
298:
191:, in reference to the chamber holding simulation
103:are easier to break apart (not only due to fewer
1055:
185:The term "Pribnow box" is used in episode 13 of
126:Probability of occurrence of each nucleotide in
475:
367:
294:
292:
78:The Pribnow box has a function similar to the
1038:
554:
222:
220:
90:: it is recognized and bound by a subunit of
410:
289:
1045:
1031:
561:
547:
217:
518:
452:
393:
344:
326:
272:
254:
368:Feklistov, Andrey; Darst, Seth (2011).
226:
47:, etc.) that is an essential part of a
1056:
707:Histone acetylation and deacetylation
542:
997:
13:
14:
1080:
1001:
911:Archaeal transcription factor B
469:
361:
1:
227:Pribnow, David (March 1975).
210:
180:
1017:. You can help Knowledge by
82:that occurs in promoters in
7:
198:
10:
1085:
996:
587:Transcriptional regulation
386:10.1016/j.cell.2011.10.041
954:
919:
893:
818:
784:Transcription coregulator
776:
753:
730:
720:Histone acetyltransferase
690:Histone methyltransferase
668:Histone-modifying enzymes
666:
659:
594:
585:
107:, but also due to weaker
63:. It is an idealized or
885:Internal control region
188:Neon Genesis Evangelion
490:Nucleic Acids Research
424:Nucleic Acids Research
195:for testing purposes.
978:Intrinsic termination
743:DNA methyltransferase
503:10.1093/nar/15.5.2343
328:10.1073/pnas.72.2.737
256:10.1073/pnas.72.3.784
1064:Regulatory sequences
755:Chromatin remodeling
176:From Harley et al.:
25:Pribnow-Schaller box
712:Histone deacetylase
702:Histone demethylase
686:Histone methylation
482:promoter sequences"
319:1975PNAS...72..737S
247:1975PNAS...72..784P
177:
27:) is a sequence of
23:(also known as the
437:10.1093/nar/gkj454
175:
114:It is named after
65:consensus sequence
1026:
1025:
991:
990:
946:RNA polymerase II
814:
813:
772:
771:
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1076:
1047:
1040:
1033:
1005:
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868:Response element
851:Response element
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497:(5): 2343–2361.
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994:
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749:
732:DNA methylation
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17:
12:
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5:
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1069:Genetics stubs
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1006:
989:
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942:RNA polymerase
936:
930:RNA polymerase
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431:(2): 564–574.
409:
380:(6): 1257–69.
360:
313:(2): 737–741.
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241:(3): 784–788.
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120:Heinz Schaller
105:hydrogen bonds
92:RNA polymerase
15:
9:
6:
4:
3:
2:
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1013:article is a
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649:trp repressor
647:
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644:lac repressor
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628:
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579:
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571:
570:Transcription
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485:(PDF, 0.9 MB)
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478:"Analysis of
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116:David Pribnow
112:
110:
109:base stacking
106:
102:
98:
93:
89:
85:
81:
76:
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70:
66:
62:
58:
57:transcription
54:
50:
46:
42:
38:
34:
30:
26:
22:
1019:expanding it
1008:
993:
830:
494:
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377:
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363:
310:
304:
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186:
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127:
113:
77:
72:
69:-10 sequence
68:
59:to occur in
28:
24:
20:
18:
955:Termination
831:Pribnow box
799:Corepressor
794:Coactivator
595:prokaryotic
193:Evangelions
33:nucleotides
21:Pribnow box
1058:Categories
983:Rho factor
973:Terminator
964:eukaryotic
939:eukaryotic
920:Elongation
906:Eukaryotic
894:Initiation
677:nucleosome
660:eukaryotic
632:gal operon
627:ara operon
622:Gua Operon
617:gab operon
612:trp operon
607:lac operon
578:Eukaryotic
211:References
181:In fiction
111:effects).
84:eukaryotes
959:bacterial
927:bacterial
901:Bacterial
875:Insulator
819:Promotion
789:Activator
639:Repressor
574:Bacterial
511:0305-1048
445:0305-1048
337:1091-6490
265:1091-6490
1011:genetics
880:Silencer
858:Enhancer
846:CAAT box
836:TATA box
826:Promoter
463:16449200
404:22136875
205:TATA box
199:See also
80:TATA box
61:bacteria
51:site on
49:promoter
806:Inducer
673:histone
529:3550697
480:E. coli
454:1360284
395:3245737
355:1054851
315:Bibcode
283:1093168
243:Bibcode
128:E. coli
101:thymine
97:adenine
88:archaea
73:element
45:thymine
41:adenine
37:thymine
31:of six
602:Operon
527:
520:340638
517:
509:
461:
451:
443:
402:
392:
353:
346:432391
343:
335:
281:
274:432404
271:
263:
29:TATAAT
1009:This
863:E-box
715:HDAC1
1015:stub
934:rpoB
777:both
764:CHD7
695:EZH2
525:PMID
507:ISSN
459:PMID
441:ISSN
400:PMID
374:Cell
351:PMID
333:ISSN
306:PNAS
279:PMID
261:ISSN
234:PNAS
171:89%
118:and
99:and
86:and
55:for
19:The
841:BRE
515:PMC
499:doi
449:PMC
433:doi
390:PMC
382:doi
378:147
341:PMC
323:doi
269:PMC
251:doi
168:49%
165:59%
162:52%
159:89%
156:82%
71:or
53:DNA
1060::
944::
932::
679:):
576:,
523:.
513:.
505:.
495:15
493:.
487:.
457:.
447:.
439:.
429:34
427:.
421:.
398:.
388:.
376:.
372:.
349:.
339:.
331:.
321:.
311:72
309:.
303:.
291:^
277:.
267:.
259:.
249:.
239:72
237:.
231:.
219:^
151:T
122:.
43:,
39:,
1046:e
1039:t
1032:v
1021:.
966:)
961:,
957:(
757::
734::
688:/
675:/
671:(
580:)
572:(
562:e
555:t
548:v
531:.
501::
465:.
435::
406:.
384::
357:.
325::
317::
285:.
253::
245::
148:A
145:A
142:T
139:A
136:T
35:(
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