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Metabolite

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489: 255:, form as part of the natural biochemical process of degrading and eliminating the compounds. The rate of degradation of a compound is an important determinant of the duration and intensity of its action. Understanding how pharmaceutical compounds are 441:
Obach, R. Scott; Esbenshade, Timothy A. (April 2013). "Pharmacologically Active Drug Metabolites: Impact on Drug Discovery and Pharmacotherapy".
334: 46:. Metabolites have various functions, including fuel, structure, signaling, stimulatory and inhibitory effects on 295:, the study of global metabolite profiles in a system (cell, tissue, or organism) under a given set of conditions 412: 493: 17: 287: 303: 281: 78: 51: 369: 85: 8: 509: 373: 466: 393: 124: 70: 55: 458: 385: 330: 298: 248: 241: 397: 450: 377: 185: 470: 360:
Demain, Arnold L. (December 1980). "Microbial production of primary metabolites".
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forms a large network of metabolic reactions, where outputs from one enzymatic
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Examples of primary metabolites produced by industrial microbiology include:
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is not directly involved in those processes, but usually has an important
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is directly involved in normal "growth", development, and reproduction.
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to an enzyme), defense, and interactions with other organisms (e.g.
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Some antibiotics use primary metabolites as precursors, such as
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exemplifies a primary metabolite produced large-scale by
501: 50:, catalytic activity of their own (usually as a 440: 107:, which is created from the primary metabolite 263:of their metabolites is an important part of 422:. United States Food and Drug Administration 27:Intermediate or end product of metabolism 244:are inputs to other chemical reactions. 14: 502: 359: 348:metabolite Any product of metabolism. 326:Taber's Cyclopedic Medical Dictionary 322: 284:, also called intermediate metabolism 38:is an intermediate or end product of 353: 24: 410: 25: 521: 481: 100:such as resins and terpenes etc. 487: 123:, which are both present in the 42:. The term is usually used for 434: 404: 316: 13: 1: 309: 7: 323:Venes, Donald, ed. (1940). 270: 92:function. Examples include 10: 526: 288:Metabolic control analysis 304:Volatile organic compound 115:are metabolites, such as 443:Pharmacological Reviews 282:Intermediary metabolism 79:industrial microbiology 251:, whether inherent or 455:10.1124/pr.111.005439 496:at Wikimedia Commons 86:secondary metabolite 374:1980NW.....67..582D 362:Naturwissenschaften 411:Harris, Edward D. 382:10.1007/BF00396537 259:and the potential 249:chemical compounds 125:metabolic pathways 71:primary metabolite 492:Media related to 299:Metabolic pathway 247:Metabolites from 242:chemical reaction 234: 233: 175:5' guanylic acid 16:(Redirected from 517: 491: 475: 474: 438: 432: 431: 429: 427: 417: 408: 402: 401: 357: 351: 350: 345: 343: 320: 186:Isoascorbic acid 133: 132: 21: 525: 524: 520: 519: 518: 516: 515: 514: 500: 499: 484: 479: 478: 439: 435: 425: 423: 415: 409: 405: 368:(12): 582–587. 358: 354: 341: 339: 337: 321: 317: 312: 273: 229: 44:small molecules 28: 23: 22: 15: 12: 11: 5: 523: 513: 512: 498: 497: 483: 482:External links 480: 477: 476: 449:(2): 578–640. 433: 403: 352: 335: 314: 313: 311: 308: 307: 306: 301: 296: 290: 285: 279: 277:Antimetabolite 272: 269: 265:drug discovery 253:pharmaceutical 232: 231: 227: 223: 217: 216: 211: 205: 204: 195: 189: 188: 183: 177: 176: 173: 167: 166: 157: 151: 150: 145: 141: 140: 137: 26: 9: 6: 4: 3: 2: 522: 511: 508: 507: 505: 495: 490: 486: 485: 472: 468: 464: 460: 456: 452: 448: 444: 437: 421: 414: 407: 399: 395: 391: 387: 383: 379: 375: 371: 367: 363: 356: 349: 338: 336:9780803659407 332: 328: 327: 319: 315: 305: 302: 300: 297: 294: 291: 289: 286: 283: 280: 278: 275: 274: 268: 266: 262: 258: 254: 250: 245: 243: 239: 230: 224: 222: 219: 218: 215: 212: 210: 207: 206: 203: 199: 196: 194: 193:Organic acids 191: 190: 187: 184: 182: 179: 178: 174: 172: 169: 168: 165: 164:aspartic acid 161: 160:Glutamic acid 158: 156: 153: 152: 149: 146: 143: 142: 138: 135: 134: 131: 128: 126: 122: 118: 114: 110: 106: 101: 99: 95: 91: 87: 82: 80: 76: 72: 67: 65: 61: 57: 53: 49: 45: 41: 37: 33: 19: 446: 442: 436: 424:. Retrieved 419: 406: 365: 361: 355: 347: 340:. Retrieved 325: 318: 293:Metabolomics 261:side effects 246: 235: 181:Antioxidants 129: 102: 83: 68: 35: 32:biochemistry 29: 494:Metabolites 257:metabolized 202:lactic acid 198:Acetic acid 171:Nucleotides 155:Amino acids 105:actinomycin 94:antibiotics 18:Metabolites 510:Metabolism 310:References 238:metabolome 109:tryptophan 90:ecological 64:pheromones 40:metabolism 36:metabolite 504:Category 463:23406671 426:28 April 398:21590956 342:16 March 271:See also 221:Vitamins 214:Glycerol 139:Example 117:fructose 98:pigments 75:Ethylene 60:odorants 56:pigments 52:cofactor 420:FDA.gov 390:7231563 370:Bibcode 209:Polyols 148:Ethanol 144:Alcohol 121:glucose 111:. Some 48:enzymes 471:720243 469:  461:  396:  388:  333:  113:sugars 62:, and 467:S2CID 416:(PDF) 394:S2CID 136:Class 459:PMID 428:2017 386:PMID 344:2020 331:ISBN 236:The 96:and 34:, a 451:doi 378:doi 119:or 66:). 30:In 506:: 465:. 457:. 447:65 445:. 418:. 392:. 384:. 376:. 366:67 364:. 346:. 267:. 200:, 162:, 127:. 84:A 81:. 69:A 58:, 473:. 453:: 430:. 400:. 380:: 372:: 228:2 226:B 20:)

Index

Metabolites
biochemistry
metabolism
small molecules
enzymes
cofactor
pigments
odorants
pheromones
primary metabolite
Ethylene
industrial microbiology
secondary metabolite
ecological
antibiotics
pigments
actinomycin
tryptophan
sugars
fructose
glucose
metabolic pathways
Ethanol
Amino acids
Glutamic acid
aspartic acid
Nucleotides
Antioxidants
Isoascorbic acid
Organic acids

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