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As a medical academic, Dr. Zago has supervised ca. 20 PhD or MSc theses, and most of his former graduate students are now researchers in different universities. Apart from his research group in Ribeirão Preto, his students have founded two other prominent research nuclei of human population genetics
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of the
Amerindian populations, the relationship with the founder populations, and the black Brazilian populations. His laboratory and his collaborators have contributed the largest volume of data on DNA markers in the Brazilian populations thus
305:. These data demonstrated that this Black population is significantly different from its U.S. or Caribbean counterparts, with implications for the medical genetic studies that compare these populations and for the understanding of the
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O gene (from the ABO blood group), showing that the group O variants have a heterogeneous ethnic distribution and identified the molecular basis of this diversity, describing at least seven new molecular variants of the blood group O
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Olsson, ML; Guerreiro, JF; Zago, MA; Chester, MA (29 May 1997). "Molecular analysis of the O alleles at the blood group ABO locus in populations of different ethnic origin reveals novel crossing-over events and point mutations".
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Franco, RF; Reitsma, PH; Lourenço, D; Maffei, FH; Morelli, V; Tavella, MH; Araújo, AG; Piccinato, CE; Zago, MA (May 1999). "Factor XIII Val34Leu is a genetic factor involved in the etiology of venous thrombosis".
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Identified for the first time in the country and described the genetic, the biochemical and the clinical features of several structural defects of hemoglobins and thalassemia variants, including a
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produced in adults is genetically determined. The molecular bases for this inheritance are complex, involving at least three loci, and are of importance for the treatment of hereditary
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Santos, SE; Ribeiro-Dos-Santos, AK; Meyer, D; Zago, MA (July 1996). "Multiple founder haplotypes of mitochondrial DNA in
Amerindians revealed by RFLP and sequencing".
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Zago, MA; Silva WA, Jr; Dalle, B; Gualandro, S; Hutz, MH; Lapoumeroulie, C; Tavella, MH; Araujo, AG; Krieger, JE; Elion, J; Krishnamoorthy, R (February 2000).
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Studied the contribution of genetic factors to the origin of thrombosis, including the role of mutations of several genes, related or not to the
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system. One mutation of especial interest involves de coagulation factor XIII and protects against the occurrence of arterial thrombosis.
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Adapted from the official biography at the
Brazilian Academy of Sciences, by permission of the biographed.
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whose genome was completely sequenced, and the FAPESP/LICR Human Cancer Genome
Project, that studied the
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tissues, and generated one of the largest contributions of gene expression to public databases.
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Zago, MA; Wood, WG; Clegg, JB; Weatherall, DJ; O'Sullivan, M; Gunson, H (May 1979).
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Zago, MA; Bottura, C (September 1983). "Splenic function in sickle-cell diseases".
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This group soon attracted attention with the following achievements, among others:
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gene, he demonstrated that the
Brazilian black population is predominantly of
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567:"Atypical beta(s) haplotypes are generated by diverse genetic mechanisms"
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10.1002/(sici)1096-8652(200002)63:2<79::aid-ajh4>3.0.co;2-d
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group with a major scientific interest in the genetic bases of
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Commanders of the
National Order of Scientific Merit (Brazil)
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presented by the
Presidency of the Republic on August 2000.
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gene that is responsible for most of the cases of familial
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Revealed an until then unsuspected heterogeneity of the
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responsible for the
Brazilian form of HbF persistence.
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343:). He participates in two consortia coordinated by
174:degree (1975), under the supervision of Professor
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321:have contributed to the understanding of the
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466:"Genetic control of F cells in human adults"
297:origin, with a lesser contribution from the
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277:of Brazilian populations, especially the
216:Demonstrated that the residual amount of
66:Learn how and when to remove this message
189:After his post-doctoral training at the
178:, one of the most outstanding Brazilian
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29:This article includes a list of general
193:, in the laboratories of Professor Sir
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301:and very little contribution from the
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677:Brazilian people of Italian descent
379:Brazilian Order of Scientific Merit
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542:10.1111/j.1469-1809.1996.tb01194.x
35:it lacks sufficient corresponding
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107:, who is active in the fields of
241:Identified molecular defects in
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162:in 1970, where he received the
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571:American Journal of Hematology
231:in the promoter region of the
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375:Brazilian Academy of Sciences
247:Identified a mutation of the
373:Dr. Zago is a member of the
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483:10.1182/blood.V53.5.977.977
377:and holds a Commend of the
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399:Thrombosis and Haemostasis
622:(in Brazilian Portuguese)
351:): the sequencing of the
129:molecular basis of cancer
530:Annals of Human Genetics
667:Brazilian hematologists
160:University of São Paulo
141:University of São Paulo
50:more precise citations.
449:10.1006/bbrc.1997.6713
411:10.1055/s-0037-1614552
207:hematological diseases
150:Dr. Zago graduated in
103:and prominent medical
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672:Brazilian oncologists
339:) and hematology (in
275:physical anthropology
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616:"Marco Antonio Zago"
253:hypercholesterolemia
692:People from Birigui
307:hereditary diseases
133:population genetics
109:hereditary diseases
353:Xylella fastidiosa
291:sickle cell anemia
285:. On the basis of
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139:) and dean of the
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83:Marco Antonio Zago
513:10.1042/cs0650297
323:genetic diversity
311:mitochondrial DNA
268:blood coagulation
191:Oxford University
99:) is a Brazilian
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657:1946 births
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279:Amerindians
260:blood group
243:hemophilias
117:hemoglobins
48:introducing
651:Categories
626:2023-06-19
385:References
368:neoplastic
303:Senegambia
255:in Brazil.
166:degree in
131:and human
125:thrombosis
31:references
620:fapesp.br
366:in human
154:from the
105:scientist
101:physician
97:São Paulo
614:FAPESP.
601:Specific
593:10629573
558:21286889
427:11358611
419:10365735
341:Campinas
281:and the
203:research
168:medicine
152:Medicine
121:clotting
638:Sources
550:8865991
521:6872464
457:9175793
390:General
222:anemias
158:of the
111:of the
93:Birigüi
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356:genome
345:FAPESP
313:, the
283:Blacks
145:Fapesp
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554:S2CID
470:Blood
423:S2CID
333:Belém
319:VNTRs
299:Benin
295:Bantu
263:gene.
249:LDL-r
172:Ph.D.
164:M.Sc.
113:blood
589:PMID
546:PMID
517:PMID
488:PMID
453:PMID
415:PMID
349:LICR
337:Pará
331:(in
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236:gene
182:and
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