279:
240:
217:
263:
20:
574:
567:
521:
Zatloukal, K; French, SW; Strumptner, C; Strnad, P; Harada, M; Toivola, DM; Cadrin, M; Omary, MB (2007). "From
Mallory to Mallory-Denk bodies: what, how and why?".
560:
342:"Formation and involution of Mallory bodies ("alcoholic hyalin") in murine and human liver revealed by immunofluorescence microscopy with antibodies to prekeratin"
239:
262:
216:
278:
184:, who first described the structures in 1911. A renaming as Mallory–Denk bodies was proposed in 2007 to honor the contribution of Austrian pathologist
185:
552:
121:
482:"In vitro production of Mallory bodies and intracellular hyaline bodies: The central role of sequestosome 1 / p62"
795:
445:
Michel, RP; Limacher, JJ; Kimoff, RJ (January 1982). "Mallory bodies in scar adenocarcinoma of the lung".
1206:
132:(8%), among other conditions. However, it has also been reported in certain other unrelated conditions.
1180:
117:
398:"The Mallory body: morphological, clinical and experimental studies (Part 1 of a literature survey)"
1089:
288:
125:
1211:
1135:
715:
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292:
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19:
1125:
1115:
1057:
992:
906:
346:
Proceedings of the
National Academy of Sciences of the United States of America
169:
129:
47:
480:
Stumptner, Conny; Fuchsbichler, Andrea; Zatloukal, Kurt; Denk, Helmut (2007).
340:
Denk, H; Franke, WW; Eckerstorfer, R; Schmid, E; Kerjaschki, D (August 1979).
1200:
1130:
911:
805:
785:
1007:
1002:
868:
634:
542:
507:
414:
397:
358:
253:
230:
145:
141:
39:
466:
423:
1160:
1037:
668:
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71:
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844:
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826:
678:
673:
639:
624:
245:
222:
153:
102:
23:
498:
481:
651:
644:
619:
161:
149:
67:
1025:
954:
878:
614:
157:
479:
329:– via The University of Utah Eccles Health Sciences Library.
964:
959:
688:
591:
1081:
609:
520:
916:
765:
94:
liver disease and were once thought to be specific for that.
87:
339:
321:. The Internet Pathology Laboratory for Medical Education
188:
for the molecular analysis of the pathogenesis of MDBs.
444:
148:. The bodies themselves are made up of intermediate
1198:
568:
391:
389:
387:
307:
86:Mallory bodies are classically found in the
395:
575:
561:
384:
497:
413:
367:
357:
180:It is named for the American pathologist
81:
18:
34:appearance (centre of image - within a
1199:
556:
200:– another histopathologic finding of
164:, or bound by other proteins such as
208:
13:
272:, as seen in alcohol use disorder.
268:Liver micrograph showing abundant
14:
1223:
112:They are a recognized feature of
16:Pathologic finding in liver cells
396:Jensen, K; Gluud, C (Oct 1994).
277:
261:
238:
215:
252:. Original magnification 200X.
229:. Original magnification 400X.
514:
473:
438:
333:
74:. Mallory bodies are damaged
1:
459:10.1016/S0046-8177(82)80143-3
300:
135:
7:
796:Charcot's cholangitis triad
535:10.1016/j.yexcr.2007.04.024
191:
10:
1228:
523:Experimental Cell Research
140:Mallory bodies are highly
1181:Sister Mary Joseph nodule
1103:
1080:
1018:
985:
942:
899:
892:
835:
757:
598:
175:
118:primary biliary cirrhosis
90:of people suffering from
289:hepatocellular carcinoma
144:and thus appear pink on
126:hepatocellular carcinoma
97:They are most common in
78:within the liver cells.
30:with the characteristic
198:Ballooning degeneration
122:non-alcoholic cirrhosis
588:human digestive system
415:10.1002/hep.1840200440
359:10.1073/pnas.76.8.4112
76:intermediate filaments
43:
874:Obstructed defecation
109:(prevalence of 51%).
82:Associated conditions
36:ballooning hepatocyte
22:
1136:Aure-Rozanova's sign
1095:Hannington-Kiff sign
1090:Howship–Romberg sign
1048:Aortic insufficiency
950:Abdominal distension
315:"Cell Injury No. 39"
701:Chilaiditi syndrome
408:(4 Pt 1): 1061–77.
166:heat shock proteins
107:alcoholic cirrhosis
99:alcoholic hepatitis
1207:Alcohol and health
1068:Grey Turner's sign
998:Hepatosplenomegaly
927:Abdominal guarding
859:Fecal occult blood
850:Fecal incontinence
821:Mirizzi's syndrome
731:Sherren's triangle
584:Signs and symptoms
182:Frank Burr Mallory
44:
1194:
1193:
1166:Fothergill's sign
1156:Rosenstein's sign
1076:
1075:
1031:Mallet-Guy's sign
970:Shifting dullness
791:Courvoisier's law
529:(10): 2033–2049.
499:10.1002/hep.21744
209:Additional images
60:Mallory's hyaline
56:Mallory–Denk body
1219:
897:
896:
884:Rectal discharge
800:Reynolds' pentad
739:Radiologic signs
726:McBurney's point
600:Gastrointestinal
586:relating to the
577:
570:
563:
554:
553:
547:
546:
518:
512:
511:
501:
477:
471:
470:
442:
436:
435:
417:
393:
382:
381:
371:
361:
337:
331:
330:
328:
326:
311:
281:
265:
242:
219:
114:Wilson's disease
1227:
1226:
1222:
1221:
1220:
1218:
1217:
1216:
1197:
1196:
1195:
1190:
1151:Lockwood's sign
1099:
1072:
1043:Ballance's sign
1014:
981:
975:Fluid wave test
938:
932:Blumberg's sign
888:
864:Rectal tenesmus
831:
771:Councilman body
753:
696:Goodsall's rule
684:Hypersalivation
601:
594:
581:
551:
550:
519:
515:
478:
474:
447:Human Pathology
443:
439:
394:
385:
338:
334:
324:
322:
313:
312:
308:
303:
296:
293:Trichrome stain
282:
273:
266:
257:
243:
234:
220:
211:
202:steatohepatitis
194:
178:
160:that have been
138:
92:alcohol-induced
84:
17:
12:
11:
5:
1225:
1215:
1214:
1212:Histopathology
1209:
1192:
1191:
1189:
1188:
1186:Blumer's shelf
1183:
1178:
1176:Massouh's sign
1173:
1171:Carnett's sign
1168:
1163:
1158:
1153:
1148:
1143:
1138:
1133:
1128:
1126:Hamburger sign
1123:
1121:Rovsing's sign
1118:
1116:Obturator sign
1113:
1107:
1105:
1101:
1100:
1098:
1097:
1092:
1086:
1084:
1078:
1077:
1074:
1073:
1071:
1070:
1065:
1060:
1055:
1053:Castell's sign
1050:
1045:
1040:
1035:
1034:
1033:
1022:
1020:
1016:
1015:
1013:
1012:
1011:
1010:
1005:
995:
993:Abdominal mass
989:
987:
983:
982:
980:
979:
978:
977:
972:
967:
962:
957:
946:
944:
940:
939:
937:
936:
935:
934:
929:
924:
919:
914:
907:Abdominal pain
903:
901:
894:
890:
889:
887:
886:
881:
876:
871:
866:
861:
856:
847:
841:
839:
833:
832:
830:
829:
824:
818:
813:
802:
793:
788:
779:
778:
773:
761:
759:
755:
754:
752:
751:
746:
744:Hampton's line
734:
733:
728:
723:
718:
713:
708:
703:
698:
692:
691:
686:
681:
676:
671:
666:
665:
664:
659:
649:
648:
647:
642:
637:
627:
622:
617:
612:
606:
604:
596:
595:
580:
579:
572:
565:
557:
549:
548:
513:
492:(3): 851–860.
472:
437:
383:
332:
305:
304:
302:
299:
298:
297:
285:Mallory bodies
283:
276:
274:
270:Mallory bodies
267:
260:
258:
244:
237:
235:
221:
214:
210:
207:
206:
205:
193:
190:
177:
174:
170:Sequestosome 1
137:
134:
130:morbid obesity
83:
80:
48:histopathology
15:
9:
6:
4:
3:
2:
1224:
1213:
1210:
1208:
1205:
1204:
1202:
1187:
1184:
1182:
1179:
1177:
1174:
1172:
1169:
1167:
1164:
1162:
1159:
1157:
1154:
1152:
1149:
1147:
1144:
1142:
1141:Dunphy's sign
1139:
1137:
1134:
1132:
1131:Heel tap sign
1129:
1127:
1124:
1122:
1119:
1117:
1114:
1112:
1109:
1108:
1106:
1102:
1096:
1093:
1091:
1088:
1087:
1085:
1083:
1079:
1069:
1066:
1064:
1063:Cullen's sign
1061:
1059:
1056:
1054:
1051:
1049:
1046:
1044:
1041:
1039:
1036:
1032:
1029:
1028:
1027:
1024:
1023:
1021:
1017:
1009:
1006:
1004:
1001:
1000:
999:
996:
994:
991:
990:
988:
984:
976:
973:
971:
968:
966:
963:
961:
958:
956:
953:
952:
951:
948:
947:
945:
941:
933:
930:
928:
925:
923:
920:
918:
915:
913:
912:Acute abdomen
910:
909:
908:
905:
904:
902:
898:
895:
891:
885:
882:
880:
877:
875:
872:
870:
867:
865:
862:
860:
857:
855:
851:
848:
846:
843:
842:
840:
838:
834:
828:
825:
822:
819:
817:
816:LĂ©pine's sign
814:
812:
811:Murphy's sign
808:
807:
806:cholecystitis
803:
801:
797:
794:
792:
789:
787:
784:
781:
780:
777:
774:
772:
769:
767:
763:
762:
760:
756:
750:
747:
745:
742:
740:
736:
735:
732:
729:
727:
724:
722:
721:Markle's sign
719:
717:
716:Arapov's sign
714:
712:
709:
707:
704:
702:
699:
697:
694:
693:
690:
687:
685:
682:
680:
677:
675:
672:
670:
667:
663:
660:
658:
657:oropharyngeal
655:
654:
653:
650:
646:
643:
641:
638:
636:
633:
632:
631:
628:
626:
623:
621:
618:
616:
613:
611:
608:
607:
605:
603:
597:
593:
589:
585:
578:
573:
571:
566:
564:
559:
558:
555:
544:
540:
536:
532:
528:
524:
517:
509:
505:
500:
495:
491:
487:
483:
476:
468:
464:
460:
456:
452:
448:
441:
433:
429:
425:
421:
416:
411:
407:
403:
399:
392:
390:
388:
379:
375:
370:
365:
360:
355:
352:(8): 4112–6.
351:
347:
343:
336:
320:
316:
310:
306:
294:
290:
286:
280:
275:
271:
264:
259:
255:
254:H&E stain
251:
247:
241:
236:
232:
231:H&E stain
228:
224:
218:
213:
212:
203:
199:
196:
195:
189:
187:
183:
173:
171:
167:
163:
162:ubiquitinated
159:
155:
151:
150:cytokeratin 8
147:
146:H&E stain
143:
133:
131:
127:
123:
119:
115:
110:
108:
104:
100:
95:
93:
89:
79:
77:
73:
69:
66:found in the
65:
61:
57:
53:
49:
41:
40:H&E stain
37:
33:
29:
25:
21:
1146:Alder's sign
1008:Splenomegaly
1003:Hepatomegaly
869:Constipation
804:
782:
776:Mallory body
775:
764:
749:Klemm's sign
737:
711:Aaron's sign
706:Dance's sign
635:Trichophagia
526:
522:
516:
489:
485:
475:
450:
446:
440:
405:
401:
349:
345:
335:
323:. Retrieved
318:
309:
284:
269:
250:Mallory body
249:
227:Mallory body
226:
179:
142:eosinophilic
139:
111:
105:of 65%) and
96:
85:
59:
55:
52:Mallory body
51:
45:
32:twisted-rope
31:
28:Mallory body
27:
1161:Cupola sign
1058:Kehr's sign
1038:Puddle sign
669:Odynophagia
453:(1): 81–5.
186:Helmut Denk
72:liver cells
1201:Categories
1111:Psoas sign
943:Distension
922:Baby colic
854:encopresis
845:Flatulence
837:Defecation
827:Nardi test
786:Boas' sign
679:Xerostomia
674:Bad breath
662:esophageal
640:Pagophagia
625:Aerophagia
486:Hepatology
402:Hepatology
325:25 October
301:References
248:showing a
246:Micrograph
225:showing a
223:Micrograph
136:Appearance
128:(23%) and
103:prevalence
58:(MDB), or
26:showing a
24:Micrograph
758:Accessory
652:Dysphagia
645:Geophagia
620:Heartburn
168:, or p62/
156:filament
68:cytoplasm
64:inclusion
1026:Jaundice
955:Bloating
879:Diarrhea
783:biliary:
615:Vomiting
543:17531973
508:17685470
432:44400893
192:See also
158:proteins
965:Tympany
960:Ascites
893:Abdomen
689:Burping
592:abdomen
467:6176520
424:7927209
319:WebPath
124:(24%),
120:(24%),
116:(25%),
1082:Hernia
986:Masses
610:Nausea
541:
506:
465:
430:
422:
378:386356
376:
369:383988
366:
176:Eponym
88:livers
62:is an
1104:Other
1019:Other
917:Colic
766:liver
602:tract
428:S2CID
900:Pain
852:and
630:Pica
539:PMID
504:PMID
463:PMID
420:PMID
374:PMID
327:2023
50:, a
590:or
531:doi
527:313
494:doi
455:doi
410:doi
364:PMC
354:doi
287:in
70:of
46:In
38:).
1203::
537:.
525:.
502:.
490:46
488:.
484:.
461:.
451:13
449:.
426:.
418:.
406:20
404:.
400:.
386:^
372:.
362:.
350:76
348:.
344:.
317:.
291:.
172:.
154:18
54:,
823:)
809:(
798:/
768::
741::
576:e
569:t
562:v
545:.
533::
510:.
496::
469:.
457::
434:.
412::
380:.
356::
295:.
256:.
233:.
204:.
152:/
101:(
42:.
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
