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MUBII-TB-DB

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are tagged as "High-Confident" based on the criteria set by Sandgren et al. MUBII-TB-DB provides a platform that is easy to use for even users that are not trained in
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search against previously mutated sequences. 2). Alignment of query sequences with wild-type sequences. MUBII outputs graphs of alignments and description of the
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Sandgren, Andreas; Strong, Michael; Muthukrishnan, Preetika; Weiner, Brian K; Church, George M; Murray, Megan B (2009-02-10).
609: 568: 604: 375:"Molecular basis and mechanisms of drug resistance in Mycobacterium tuberculosis: classical and new drugs" 216:"MUBII-TB-DB: a database of mutations associated with antibiotic resistance in Mycobacterium tuberculosis" 142: 561: 133: 88: 594: 163: 8: 541: 137: 505: 470: 250: 215: 350: 317: 286: 549: 510: 492: 451: 443: 404: 396: 355: 337: 298: 290: 255: 237: 162:, gyrA, gyrB, and rrs. MUBII analyzes the query using two parallel strategies: 1). A 68: 500: 482: 435: 386: 345: 329: 282: 245: 227: 487: 545: 273:
Heym, B (February 1997). "Multidrug resistance in Mycobacterium tuberculosis".
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A database that documents and tracks tuberculosis antibiotic resistance genes.
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Flandrois, Jean-Pierre; Lina, GΓ©rard; Dumitrescu, Oana (December 2014).
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Zhang, Y.; Yew, W-W. (2015-11-01). "Mechanisms of drug resistance in
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The International Journal of Tuberculosis and Lung Disease
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Almeida Da Silva, P. E.; Palomino, J. C. (2011-07-01).
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and therapeutic significance. Therapeutically relevant
586: 471:"Tuberculosis Drug Resistance Mutation Database" 569: 275:International Journal of Antimicrobial Agents 136:genes. It is a highly structured, text-based 576: 562: 504: 486: 390: 349: 249: 231: 421: 43:Tuberculosis antibiotic resistance genes 600:Antimicrobial resistance organizations 587: 315: 379:Journal of Antimicrobial Chemotherapy 528: 272: 209: 207: 205: 203: 13: 188:Antimicrobial Resistance databases 14: 621: 200: 532: 462: 415: 366: 309: 266: 1: 322:Clinical Microbiology Reviews 287:10.1016/s0924-8579(96)00356-1 193: 548:. You can help Knowledge by 488:10.1371/journal.pmed.1000002 316:Musser, J M (October 1995). 7: 181: 10: 626: 527: 424:Mycobacterium tuberculosis 143:Mycobacterium tuberculosis 610:Biological database stubs 110: 105: 83: 78: 64: 59: 47: 37: 29: 24: 233:10.1186/1471-2105-15-107 544:-related article is a 440:10.5588/ijtld.15.0389 134:antibiotic resistance 605:Biological databases 542:Biological database 334:10.1128/cmr.8.4.496 146:at seven different 21: 16:Biological database 392:10.1093/jac/dkr173 220:BMC Bioinformatics 19: 557: 556: 434:(11): 1276–1289. 120: 119: 617: 578: 571: 564: 536: 529: 519: 518: 508: 490: 466: 460: 459: 426:: update 2015". 419: 413: 412: 394: 385:(7): 1417–1430. 370: 364: 363: 353: 313: 307: 306: 270: 264: 263: 253: 235: 211: 160:mabA(fabG1)-inhA 129:that focuses on 101: 98: 96: 94: 92: 90: 89:umr5558-bibiserv 65:Primary citation 22: 18: 625: 624: 620: 619: 618: 616: 615: 614: 585: 584: 583: 582: 525: 523: 522: 481:(2): e1000002. 467: 463: 420: 416: 371: 367: 314: 310: 271: 267: 212: 201: 196: 184: 112: 87: 39: 17: 12: 11: 5: 623: 613: 612: 607: 602: 597: 581: 580: 573: 566: 558: 555: 554: 537: 521: 520: 461: 414: 365: 328:(4): 496–514. 308: 265: 198: 197: 195: 192: 191: 190: 183: 180: 176:bioinformatics 118: 117: 114: 108: 107: 103: 102: 85: 81: 80: 76: 75: 66: 62: 61: 57: 56: 51: 45: 44: 41: 35: 34: 31: 27: 26: 15: 9: 6: 4: 3: 2: 622: 611: 608: 606: 603: 601: 598: 596: 593: 592: 590: 579: 574: 572: 567: 565: 560: 559: 553: 551: 547: 543: 538: 535: 531: 530: 526: 516: 512: 507: 502: 498: 494: 489: 484: 480: 476: 475:PLOS Medicine 472: 465: 457: 453: 449: 445: 441: 437: 433: 429: 425: 418: 410: 406: 402: 398: 393: 388: 384: 380: 376: 369: 361: 357: 352: 347: 343: 339: 335: 331: 327: 323: 319: 312: 304: 300: 296: 292: 288: 284: 280: 276: 269: 261: 257: 252: 247: 243: 239: 234: 229: 225: 221: 217: 210: 208: 206: 204: 199: 189: 186: 185: 179: 177: 173: 169: 165: 161: 157: 153: 149: 145: 144: 139: 135: 132: 128: 124: 115: 109: 106:Miscellaneous 104: 100: 97:/mubii-select 86: 82: 77: 74: 70: 67: 63: 58: 55: 52: 50: 46: 42: 36: 32: 28: 23: 595:Tuberculosis 550:expanding it 539: 524: 478: 474: 464: 431: 427: 423: 417: 382: 378: 368: 325: 321: 311: 281:(1): 61–70. 278: 274: 268: 223: 219: 141: 140:focusing on 131:tuberculosis 122: 121: 111:Bookmarkable 123:MUBII-TB-DB 91:.univ-lyon1 30:Description 20:MUBII-TB-DB 589:Categories 226:(1): 107. 194:References 38:Data types 497:1549-1676 448:1027-3719 401:0305-7453 342:0893-8512 295:0924-8579 242:1471-2105 172:mutations 49:Organisms 515:19209951 456:26467578 409:21558086 303:18611785 260:24731071 182:See also 168:mutation 158:, katG; 148:mutation 138:database 127:database 113:entities 73:24731071 54:Bacteria 40:captured 506:2637921 360:8665467 251:4021062 84:Website 60:Contact 25:Content 513:  503:  495:  454:  446:  407:  399:  358:  351:172873 348:  340:  301:  293:  258:  248:  240:  150:loci: 95:/mubii 79:Access 71:  540:This 164:BLAST 125:is a 546:stub 511:PMID 493:ISSN 452:PMID 444:ISSN 405:PMID 397:ISSN 356:PMID 338:ISSN 299:PMID 291:ISSN 256:PMID 238:ISSN 156:pncA 152:rpoB 99:.cgi 69:PMID 501:PMC 483:doi 436:doi 387:doi 346:PMC 330:doi 283:doi 246:PMC 228:doi 116:yes 93:.fr 591:: 509:. 499:. 491:. 477:. 473:. 450:. 442:. 432:19 430:. 403:. 395:. 383:66 381:. 377:. 354:. 344:. 336:. 324:. 320:. 297:. 289:. 277:. 254:. 244:. 236:. 224:15 222:. 218:. 202:^ 178:. 154:, 577:e 570:t 563:v 552:. 517:. 485:: 479:6 458:. 438:: 411:. 389:: 362:. 332:: 326:8 305:. 285:: 279:8 262:. 230::

Index

Organisms
Bacteria
PMID
24731071
umr5558-bibiserv.univ-lyon1.fr/mubii/mubii-select.cgi
database
tuberculosis
antibiotic resistance
database
Mycobacterium tuberculosis
mutation
rpoB
pncA
mabA(fabG1)-inhA
BLAST
mutation
mutations
bioinformatics
Antimicrobial Resistance databases




"MUBII-TB-DB: a database of mutations associated with antibiotic resistance in Mycobacterium tuberculosis"
doi
10.1186/1471-2105-15-107
ISSN
1471-2105
PMC
4021062

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