Knowledge

PncA

Source đź“ť

252: 79:
Scorpio A, Zhang Y (June 1996). "Mutations in pncA, a gene encoding pyrazinamidase/nicotinamidase, cause resistance to the antituberculous drug pyrazinamide in tubercle bacillus".
122:
Whitfield, Michael G.; Soeters, Heidi M.; Warren, Robin M.; York, Talita; Sampson, Samantha L.; Streicher, Elizabeth M.; Helden, Paul D. van; Rie, Annelies van (2015-07-28).
293: 46: 317: 286: 327: 322: 279: 135: 8: 139: 223: 190: 166: 123: 104: 124:"A Global Perspective on Pyrazinamide Resistance: Systematic Review and Meta-Analysis" 228: 210: 171: 153: 96: 312: 218: 202: 161: 143: 108: 88: 148: 41: 263: 191:"Pyrazinamide Resistance and pncA Gene Mutations in Mycobacterium tuberculosis" 33: 23: 267: 189:
Juréen, Pontus; Werngren, Jim; Toro, Juan-Carlos; Hoffner, Sven (2016-12-15).
306: 251: 214: 157: 28: 44:. There is a strong correlation between mutations in pncA and resistance of 232: 175: 59: 37: 100: 206: 92: 259: 121: 188: 304: 287: 78: 294: 280: 72: 222: 165: 147: 305: 195:Antimicrobial Agents and Chemotherapy 246: 13: 14: 339: 250: 182: 115: 1: 65: 266:. You can help Knowledge by 149:10.1371/journal.pone.0133869 7: 53: 10: 344: 245: 262:-related article is a 207:10.1128/AAC.00110-08 140:2015PLoSO..1033869W 40:to the active form 22:is a gene encoding 93:10.1038/nm0696-662 36:converts the drug 275: 274: 50:to pyrazinamide. 335: 318:Prokaryote genes 296: 289: 282: 254: 247: 237: 236: 226: 201:(5): 1852–1854. 186: 180: 179: 169: 151: 119: 113: 112: 76: 343: 342: 338: 337: 336: 334: 333: 332: 303: 302: 301: 300: 243: 241: 240: 187: 183: 134:(7): e0133869. 120: 116: 77: 73: 68: 56: 47:M. tuberculosis 42:pyrazinoic acid 17: 12: 11: 5: 341: 331: 330: 325: 320: 315: 299: 298: 291: 284: 276: 273: 272: 255: 239: 238: 181: 114: 70: 69: 67: 64: 63: 62: 55: 52: 34:Pyrazinamidase 24:pyrazinamidase 16:Bacterial gene 15: 9: 6: 4: 3: 2: 340: 329: 326: 324: 321: 319: 316: 314: 311: 310: 308: 297: 292: 290: 285: 283: 278: 277: 271: 269: 265: 261: 256: 253: 249: 248: 244: 234: 230: 225: 220: 216: 212: 208: 204: 200: 196: 192: 185: 177: 173: 168: 163: 159: 155: 150: 145: 141: 137: 133: 129: 125: 118: 110: 106: 102: 98: 94: 90: 86: 82: 75: 71: 61: 58: 57: 51: 49: 48: 43: 39: 35: 31: 30: 29:Mycobacterium 25: 21: 328:Enzyme stubs 323:Tuberculosis 268:expanding it 257: 242: 198: 194: 184: 131: 127: 117: 87:(6): 662–7. 84: 80: 74: 60:Pyrazinamide 45: 38:pyrazinamide 27: 19: 18: 307:Categories 66:References 215:0066-4804 158:1932-6203 32:species. 233:18316515 176:26218737 128:PLOS ONE 81:Nat. Med 54:See also 313:Enzymes 224:2346646 167:4517823 136:Bibcode 109:8579133 101:8640557 260:enzyme 231:  221:  213:  174:  164:  156:  107:  99:  258:This 105:S2CID 264:stub 229:PMID 211:ISSN 172:PMID 154:ISSN 97:PMID 20:PncA 219:PMC 203:doi 162:PMC 144:doi 89:doi 26:in 309:: 227:. 217:. 209:. 199:52 197:. 193:. 170:. 160:. 152:. 142:. 132:10 130:. 126:. 103:. 95:. 83:. 295:e 288:t 281:v 270:. 235:. 205:: 178:. 146:: 138:: 111:. 91:: 85:2

Index

pyrazinamidase
Mycobacterium
Pyrazinamidase
pyrazinamide
pyrazinoic acid
M. tuberculosis
Pyrazinamide
doi
10.1038/nm0696-662
PMID
8640557
S2CID
8579133
"A Global Perspective on Pyrazinamide Resistance: Systematic Review and Meta-Analysis"
Bibcode
2015PLoSO..1033869W
doi
10.1371/journal.pone.0133869
ISSN
1932-6203
PMC
4517823
PMID
26218737
"Pyrazinamide Resistance and pncA Gene Mutations in Mycobacterium tuberculosis"
doi
10.1128/AAC.00110-08
ISSN
0066-4804
PMC

Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.

↑