Knowledge

Levo-Transposition of the great arteries

Source 📝

163:
With l-TGA, deoxygenated blood is pumped from the right atrium into the morphological left ventricle (which lies on the right side of the heart), then through the pulmonary artery to the lungs. The oxygenated blood then returns, via the pulmonary veins, to the left atrium from which it is pumped into
127:
Complex l-TGA may produce immediate or more quickly-developed symptoms, depending on the nature, degree and number of accompanying defect(s). If a right-to-left or bidirectional shunt is present, the list of symptoms may include mild
335: 320: 245:
In a number of cases, the (technically challenging) "double switch operation" has been successfully performed to restore the normal blood flow through the ventricles.
92:, this condition is described as atrioventricular discordance (ventricular inversion) with ventriculoarterial discordance. l-TGA is often referred to simply as 160:, to the left atrium from which it is pumped into the left ventricle, then through the aorta to the rest of the body, including the heart muscle itself. 116:, will over a period of years hypertrophy and may fail, because of the high pressure it is forced to work against. This may produce symptoms such as 287: 97: 230:. However, many cases of simple l-TGA are "accidentally" diagnosed in adulthood, during diagnosis or treatment of other conditions. 210:
When no other heart defects are present it is called 'simple' l-TGA; when other defects are present it is called 'complex' l-TGA.
93: 419: 74:) are transposed, with the aorta anterior and to the left of the pulmonary artery; the morphological left and right 112:
then becomes much higher than pulmonary blood pressure. The morphological right ventricle, evolved to handle a low
81:
Use of the term "corrected" has been disputed by many due to the frequent occurrence of other abnormalities and or
390: 89: 263: 30:
Congenitally corrected transposition of the great arteries (CC-TGA), L-transposition of the great arteries
188: 350: 192: 59: 56: 108:
Simple l-TGA does not produce any visually identifiable features at birth. However, systemic
184: 180: 8: 339: 344: 121: 361: 281: 219: 82: 75: 35: 173: 156:
where it is oxygenated. The oxygen-rich ("oxygenated") blood then returns, via the
71: 44: 355: 176: 157: 40: 404: 366: 149: 113: 109: 405:
Aortic balloon valvuloplasty in corrected transposition of the great arteries
329: 172:
l-TGA is often accompanied by other heart defects, the most common type being
413: 239: 204: 312: 223: 264:"Orphanet: Congenitally corrected transposition of the great arteries" 78:
with their corresponding atrioventricular valves are also transposed.
227: 238:
Simple l-TGA has a very good prognosis, with many individuals being
385: 196: 152:
into the right ventricle, then through the pulmonary artery to the
129: 96:(TGA); however, TGA is a more general term which may also refer to 63: 117: 324: 145: 200: 141: 67: 164:
the morphological right ventricle, then through the aorta.
153: 148:-depleted ("deoxygenated") blood is pumped from the right 302: 167: 411: 286:: CS1 maint: numeric names: authors list ( 98:dextro-transposition of the great arteries 53:Levo-Transposition of the great arteries 22:Levo-Transposition of the great arteries 242:and not requiring surgical correction. 412: 262:RESERVED, INSERM US14 -- ALL RIGHTS. 103: 261: 94:transposition of the great arteries 13: 14: 431: 298: 135: 255: 168:Variations and similar defects 1: 248: 233: 213: 7: 10: 436: 376: 306: 189:ventricular septal defect 34: 26: 21: 420:Congenital heart defects 193:patent ductus arteriosus 218:l-TGA can sometimes be 60:congenital heart defect 207:may also be present. 62:in which the primary 185:patent foramen ovale 181:atrial septal defect 85:in l-TGA patients. 377:External resources 104:Signs and symptoms 90:segmental analysis 83:acquired disorders 400: 399: 222:in utero with an 50: 49: 16:Medical condition 427: 304: 303: 292: 291: 285: 277: 275: 274: 259: 183:(ASD) including 72:pulmonary artery 45:medical genetics 19: 18: 435: 434: 430: 429: 428: 426: 425: 424: 410: 409: 401: 396: 395: 372: 371: 315: 301: 296: 295: 279: 278: 272: 270: 260: 256: 251: 236: 226:after 18 weeks 216: 170: 158:pulmonary veins 138: 106: 41:Cardiac surgery 17: 12: 11: 5: 433: 423: 422: 408: 407: 398: 397: 394: 393: 381: 380: 378: 374: 373: 370: 369: 358: 347: 332: 316: 311: 310: 308: 307:Classification 300: 299:External links 297: 294: 293: 253: 252: 250: 247: 235: 232: 215: 212: 169: 166: 137: 134: 114:blood pressure 110:blood pressure 105: 102: 48: 47: 38: 32: 31: 28: 24: 23: 15: 9: 6: 4: 3: 2: 432: 421: 418: 417: 415: 406: 403: 402: 392: 388: 387: 383: 382: 379: 375: 368: 364: 363: 359: 357: 353: 352: 348: 346: 342: 341: 337: 333: 331: 327: 326: 322: 318: 317: 314: 309: 305: 289: 283: 269: 268:www.orpha.net 265: 258: 254: 246: 243: 241: 231: 229: 225: 221: 211: 208: 206: 202: 198: 194: 190: 186: 182: 178: 175: 165: 161: 159: 155: 151: 147: 143: 133: 131: 125: 123: 119: 115: 111: 101: 99: 95: 91: 86: 84: 79: 77: 73: 69: 65: 61: 58: 54: 46: 42: 39: 37: 33: 29: 25: 20: 384: 360: 349: 334: 319: 271:. Retrieved 267: 257: 244: 240:asymptomatic 237: 217: 209: 174:intracardiac 171: 162: 140:In a normal 139: 136:Pathogenesis 126: 107: 87: 80: 52: 51: 191:(VSD), and 27:Other names 362:DiseasesDB 273:2017-10-14 249:References 224:ultrasound 76:ventricles 234:Treatment 228:gestation 220:diagnosed 214:Diagnosis 100:(d-TGA). 57:acyanotic 36:Specialty 414:Category 386:Orphanet 282:cite web 197:Stenosis 179:such as 130:cyanosis 70:and the 64:arteries 356:C535426 205:vessels 195:(PDA). 187:(PFO), 122:fatigue 118:dyspnea 391:216694 345:745.12 201:valves 177:shunts 150:atrium 146:oxygen 55:is an 367:13259 330:Q20.5 154:lungs 142:heart 68:aorta 66:(the 351:MeSH 340:9-CM 288:link 336:ICD 321:ICD 203:or 199:of 120:or 88:In 416:: 389:: 365:: 354:: 343:: 328:: 325:10 284:}} 280:{{ 266:. 144:, 132:. 124:. 43:, 338:- 323:- 313:D 290:) 276:.

Index

Specialty
Cardiac surgery
medical genetics
acyanotic
congenital heart defect
arteries
aorta
pulmonary artery
ventricles
acquired disorders
segmental analysis
transposition of the great arteries
dextro-transposition of the great arteries
blood pressure
blood pressure
dyspnea
fatigue
cyanosis
heart
oxygen
atrium
lungs
pulmonary veins
intracardiac
shunts
atrial septal defect
patent foramen ovale
ventricular septal defect
patent ductus arteriosus
Stenosis

Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.