653:
630:
1676:
1725:
adverse reactions, such as severe pain, burning, and blurred vision, and that the defendant, Dr. Hubbard, failed to offer him an alternative medication or refer him to an ophthalmologist. The plaintiff also claimed that he sustained permanent eye damage as a result of the ketotifen. The district court granted the defendant's motion to dismiss, finding that the plaintiff failed to state a claim upon which relief could be granted. The plaintiff appealed to the
1562:
875:, so that ketotifen prevents the binding of histamine to these receptors and thus reduces the symptoms of histamine-mediated reactions, such as itching, sneezing, wheezing, and swelling. Ketotifen also prevents the release of histamine and other inflammatory substances from immune cells called mast cells; this action helps reduce symptoms of conditions (including allergic conditions) by blocking the activation of these cells. In addition to its
38:
1856:. Serotonin is known to have suppressant effects on appetite. It is suggested that ketotifen might cause a decrease in serotonin levels due to this regulatory influence. As a result, the decrease in serotonin function may lead to increased food intake tendency and heightened appetite. Still, these potential mechanisms have been hypothesized based on limited evidence. Studies on mice suggest that
14881:
1036:, decreasing symptoms, preventing exacerbations, and reducing the use of rescue oral steroids, ketotifen has also been found to be effective when used alone or in combination with other medications. Oral ketotifen is an alternative to inhaled therapy for asthma in children, especially for younger children who may have difficulty using inhalers.
1813:), it was found that around 1 to 2 out of every 100 people who took the drug experienced weight gain, with adults gaining about 1 kilogram (2.2 lb) and children over the age of one gaining 2.8–3.3 kilograms (6.2–7.3 lb). However, in another study, adults gained a higher amount of weight: 5.0–5.4 kilograms (11.0–11.9 lb).
1014:, gastrointestinal symptoms (such as abdominal pain, diarrhea), respiratory symptoms (such as wheezing), and other systemic manifestations. Still, treatment plans for MCAS typically involve a combination of medications targeting different aspects of mast cell activation along with lifestyle modifications to minimize triggers.
1577:-based compound with antihistamine properties and the structure similar to that of ketotifen: the only difference is that ketotifen molecule has an oxygen atom that pizotifen molecule lacks—ketotifen contains a carbonyl group (C=O) in the central (7-membered) ring while pizotifen contains methylene group (-CH
1724:
by acting with deliberate indifference to his serious medical needs. The plaintiff claimed that he suffered from a chronic eye condition that required medical attention and that the defendant, Dr. Hubbard, prescribed him ketotifen. The plaintiff further claimed that the ketotifen eye drops caused him
894:
While well-tolerated, ketotifen can have side effects, including drowsiness, weight gain, dry mouth, irritability, increased nosebleeds when taken orally, and temporary burning or stinging sensations in the eyes when used in ophtalmic form. Ketotifen has contraindications for individuals with certain
1071:
The eye drops are contraindicated for individuals who have a known hypersensitivity to ketotifen or any other ingredient in the formulation, whereas drug-eluting contact lenses are contraindicated for those who experience irritation from wearing contact lenses. Eye drops are not recommended for use
1017:
The maximum antihistamine and mast cell stabilizing effect of oral ketotifen is achieved on long-term administration, and least 6-12 weeks is necessary for a maximum therapeutic effect to start. The sedation side effect decreases over time during such long-term administration, but the antihistamine
1009:
essential for mast cell activation, helps reduce symptoms of allergic conditions such as asthma, hay fever, and conjunctivitis caused by mast cell activation. In Canada, Europe, and Mexico, oral ketotifen is commonly prescribed for these indications. In patients with MCAS, ketotifen reduce episodes
1525:
of about 12 hours. Ketotifen is extensively metabolized in the liver by oxidation and conjugation, and the metabolites are excreted in the urine and feces. The bioavailability of oral ketotifen is about 50% due to hepatic first-pass metabolism. Peak plasma concentration is reached in about 2 to 4
1609:
There is no academic consensus on whether ketotifen should be classified as a medication belonging to the first or the second generations of antihistamine drugs; the classification can vary depending on the criteria used and the context of the study, and is primarily based on chemical structure,
1115:
near the corner of the eye for at least one minute and remove any excess solution with a tissue. Ketotifen safety when taken via the oral route (tablets or syrup) during pregnancy and lactation remains unknown; therefore, it is not recommended to use ketotifen orally during these periods until
953:
Drug-eluting contact lenses, which release ketotifen medication, are used to help prevent itchy eyes caused by allergies. The lenses can also correct vision problems like nearsightedness and farsightedness. These lenses are meant for people who don't have red eyes, can comfortably wear contact
1765:
hepatic metabolite of ketotifen. Unlike ketotifen, NK does not seem to induce severe sedative effects, potentially allowing for higher doses to be administered without sedation as a limiting factor. Furthermore, NK may probably have potent and dose-dependent inhibition of the release of the
1647:. While ketotifen has some sedative properties, it is generally considered to have a milder sedative effect compared to traditional first-generation antihistamines, so this reduced sedation is one of the reasons why ketotifen is sometimes classified as a second-generation antihistamine.
1367:
as a diagnostic agent. Ketotifen may affect the results of some laboratory tests, such as skin tests for allergies or blood glucose levels. Ketotifen may interfere with the skin test reactions by suppressing the histamine response, leading to false-negative results.
3532:
In the present case, a 4-month-old boy was administered ketotifen at 5 times the recommended dose, and he showed mental deterioration and growth retardation. The presence of developmental deterioration strongly suggests that overdose of ketotifen induces toxic
1025:(FDA) for adults and older children with asthma or allergic conditions. However, ketotifen eye drops are approved in the US for people who are at least three years of age. In the EU, ketotifen oral formulatios (syrup, tables and capsules) are approved by the
950:. It starts working within minutes after administering the drops. Ketotifen in the form of eye drops has not been studied in children under three years old, whereas drug-eluting contact lenses have not been studied in children under eleven years old.
4809:
Sagara A, Nagahama A, Aki H, Yoshimura H, Hiraide M, Shimizu T, et al. (October 2023). "Potential risk of driving performance under combined conditions of taking second-generation antihistamines and attending calls using a hands-free function".
1079:(a group of rare disorders that occur when the body cannot make enough of a substance called heme, which is needed for red blood cells to carry oxygen, this causes a build-up of chemicals called porphyrins, which can damage the nerves and the skin),
1703:
Ketotifen is sold under various brand names worldwide, depending on country and formulation, with over 200 different names used. In the United States, ketotifen fumarate ophtalmic solution is marketed under brand name
Zaditor, which is owned by
3582:
1463:
and exert central nervous system effects, such as sedation, weight gain, and anticonvulsant activity. Ketotifen also has peripheral effects, such as inhibition of platelet aggregation, modulation of cytokine production, and enhancement of
1666:
Ketotifen was approved for medical use in Canada in
December 1990. Ketotifen was approved for medical use in the United States in July 1999. The contact lens with ketotifen was approved for medical use in the United States in 2022.
1510:, which makes it effective in the prophylaxis and treatment of various allergic and respiratory conditions, such as asthma, allergic rhinitis, conjunctivitis, dermatitis, urticaria, and anaphylaxis. Ketotifen can also reduce the
1416:
Ketotifen also plays a role in the prevention of accumulation of eosinophils, which are white blood cells that become active during allergic reactions and infections; as such, ketotifen helps in reducing inflammation this way.
1585:
receptors by providing shape complementarity and facilitating specific interactions with amino acid residues within the receptor's binding site, which plays a role in the ability of both drugs to effectively bind and modulate
2738:
1614:
antihistamines, such as diphenhydramine, reduce skin reactivity for up to 24 hours, whereas ketotifen suppresses skin reactivity for over five days, a typical duration for the second generation of the class. Ketotifen is a
1187:
The symptoms of ketotifen overdose are dose-dependent and may vary from mild to severe. The onset of symptoms may be delayed for several hours after ingestion, and the duration of symptoms may last for more than 24 hours.
1309:
In children, ketotifen overdose may lead to toxic encephalopathy with lifelong health consequences. There was a reported case of an overdose in a 4-month-old boy that led to growth retardation and mental deterioration.
1159:. Systemic use of ketotifen may also cause abdominal pain, nausea, vomiting, constipation, diarrhea, headache, dizziness, or fatigue. In rare cases, systemic use of ketotifen may cause serious side effects such as
1095:(a condition where the iris, the colored part of the eye, bulges and blocks the drainage of fluid from the eye, causing high pressure and damage to the optic nerve, a nerve that connects the eye to the brain), and
1106:
through the eye is limited. It is unlikely to cause any adverse effects in breastfeeding infants after maternal use. To minimize the amount of medication transferred to breast milk when using eye drops, the
5333:
1643:. The sedative effects of ketotifen is also a reason in differences in classification. First-generation antihistamines are well known for their sedating side effects due to their ability to penetrate the
1318:
In systemic (oral) administration, ketotifen has the potential to enhance the effects of sedatives, hypnotics, antihistamines, and alcohol. Interactions have been observed between oral ketotifen and oral
1245:
The symptoms of ketotifen overdose may be described according to the affected system of the body. The cardiovascular effects of ketotifen overdose may include tachycardia, hypotension, arrhythmias, and
5162:
3575:
5413:"A Phase 2b Double-blind, Randomized, Placebo-controlled, Parallel-group Study of the Efficacy and Safety of Norketotifen (NKT) in the Treatment of Acute Uncomplicated Influenza-like Illness (ILI)"
1356:
In rare instances, patients who have been administered oral ketotifen with oral antidiabetic agents have exhibited a reversible decrease in thrombocyte count. As such, it is recommended to monitor
5255:
1306:. The risk of coma and death is higher in adults, especially those with pre-existing medical conditions or concomitant use of other drugs that cause sedation or lower the seizure threshold.
1043:
antagonist (a medication that blocks the action of leukotrienes, which are chemicals that cause inflammation and narrowing of the airways in some allergic and respiratory conditions) and a
5494:
2091:
Grant SM, Goa KL, Fitton A, Sorkin EM (September 1990). "Ketotifen. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in asthma and allergic disorders".
4523:"Case Report and Review of the Literature: Bullous Skin Eruption After the Booster-Dose of Influenza Vaccine in a Pediatric Patient With Polymorphic Maculopapular Cutaneous Mastocytosis"
1526:
hours. The pharmacokinetics of ketotifen are not significantly affected by age, gender, or renal impairment, but may be altered by hepatic impairment or concomitant use of other drugs.
1785:
with anti-inflammatory properties, when used as an anti-inflammatory medication. The potential future applications of norketotifen are researched by Emergo
Therapeutics, a US company.
1848:, where it inhibits appetite. By reducing TNF-α production, ketotifen may lead to decreased leptin levels, reducing appetite control inhibition. Furthermore, ketotifen's influence on
1717:
2727:
2287:
Zuberbier T, Asero R, Bindslev-Jensen C, Walter
Canonica G, Church MK, Giménez-Arnau AM, et al. (October 2009). "EAACI/GA(2)LEN/EDF/WAO guideline: management of urticaria".
1452:) activity. However, at the dosages in which it is typically used clinically, both the anticholinergic and antiserotonergic activity of ketotifen are said not to be appreciable.
3334:
1091:(a condition where the passage of food from the stomach to the small intestine is blocked by something, such as a muscle, an ulcer, a tumor, or a gallstone), susceptibility to
1032:
Oral ketotifen can be used as a long-term control medication for asthma and wheeze in children, and it has been shown to improve the control of asthma by reducing the need for
1371:
Ophthalmic use of ketotifen may interact with contact lenses, as the eye drops may contain preservatives that can be absorbed by soft contact lenses and cause eye irritation.
812:, and urticaria (hives). Ketotifen is available in ophthalmic (eye drops or drug-eluting contact lenses) and oral (tablets or syrup) forms: the ophthalmic form relieves eye
3766:"Studies on the novel antiallergic agent HSR-609: its penetration into the central nervous system in mice and guinea pigs and its selectivity for the histamine H1-receptor"
5307:
4461:
4261:
Fahmy RH, Badr-Eldin SM (August 2014). "Novel delivery approach for ketotifen fumarate: dissofilms formulation using 3² experimental design: in vitro/in vivo evaluation".
2066:
1930:
1088:
4486:
Eltze M, Mutschler E, Lambrecht G (1992). "Affinity profiles of pizotifen, ketotifen and other tricyclic antimuscarinics at muscarinic receptor subtypes M1, M2 and M3".
4707:
Triantafillou V, Maina IW, Patel NN, Tong CC, Papagiannopoulos P, Kohanski MA, et al. (February 2020). "In vitro safety of ketotifen as a topical nasal rinse".
1021:
Oral ketotifen is available at compounding pharmacies in the United States with a prescription requirement, still, the use of oral ketotifen is only approved by the
903:. Controversies surrounding ketotifen include its classification as a first-generation or second-generation antihistamine due to varying criteria of classification.
4088:
Kahhak L, Roche A, Dubray C, Arnoux C, Benveniste J (May 1996). "Decrease of ciliary beat frequency by platelet activating factor: protective effect of ketotifen".
2838:
Grahnén A, Lönnebo A, Beck O, Eckernäs SA, Dahlström B, Lindström B (May 1992). "Pharmacokinetics of ketotifen after oral administration to healthy male subjects".
11660:
4918:
4432:
1108:
13875:
8038:
6481:
5329:
4572:
Bittner L, Teixidó E, Keddi I, Escher BI, Klüver N (May 2019). "pH-Dependent Uptake and
Sublethal Effects of Antihistamines in Zebrafish (Danio rerio) Embryos".
2926:
Ketotifen has a stronger effect on stabilizing MCs than sodium cromoglycate. This drug has antihistamine activity and is also a functional leukotriene antagonist
3008:"Charge Transfer Complexes of Ketotifen with 2,3-Dichloro-5,6-dicyano-p-benzoquinone and 7,7,8,8-Tetracyanoquodimethane: Spectroscopic Characterization Studies"
10927:
1726:
1075:
For oral ketotifen, the contraindication is for known hypersensitivity to any component of the product. Caution should be taken on the following conditions:
184:
5132:
1581:-) in that position. In both ketotifen and pizotifen, the spatial restriction and reduced degrees of freedom caused by the rings enable optimal binding to H
1140:
of eyes, and rash. Ophthalmic use of ketotifen may also cause burning, stinging, or itching of the eyes, blurred vision, or increased sensitivity to light.
5369:
Aberg AK, Arulnesan N, Bolger GT, Ciofalo VB, Pucaj K, Walle K, et al. (April 2022). "Ketotifen is a
Prodrug. Norketotifen is the active metabolite".
5154:
5245:
2671:
13708:
1721:
5102:
14466:
14015:
1997:
1965:
997:
and food allergies. As a mast cell stabilizer to treat MCAS, oral ketotifen prevents the release of histamine and other inflammatory substances from
14723:
14406:
5707:"The mast cell stabiliser ketotifen decreases visceral hypersensitivity and improves intestinal symptoms in patients with irritable bowel syndrome"
5155:"Johnson & Johnson Vision Care Receives FDA Approval for Acuvue Theravision with Ketotifen – World's First and Only Drug-Eluting Contact Lens"
4378:
Jáuregui I, Mullol J, Bartra J, del
Cuvillo A, Dávila I, Montoro J, et al. (2006). "H1 antihistamines: psychomotor performance and driving".
14491:
14431:
14361:
14005:
12806:
7161:
5072:
2136:"Use of Ketotifen Fumarate-Eluting Daily Disposable Soft Contact Lens in Management of Ocular Allergy: Literature Review and Report of Two Cases"
5490:
3519:
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14679:
14611:
14476:
12944:
10348:
7633:
7628:
7568:
7528:
7437:
7417:
7136:
7056:
7036:
2767:
719:
14858:
14788:
14773:
14763:
14596:
14356:
14351:
12491:
12446:
12154:
8694:
7663:
7598:
7543:
7427:
7171:
7111:
7091:
7081:
6996:
6966:
6691:
77:
14813:
14768:
14758:
14591:
14486:
14321:
14075:
13905:
13434:
13409:
12984:
11748:
10502:
10333:
9156:
8438:
7960:
7839:
7658:
7623:
7558:
7548:
7432:
7422:
7412:
7407:
7181:
7131:
6991:
6976:
6971:
6951:
4664:
Janeczko P, Norris MR, Bielory L (October 2021). "Assessment of receptor affinities of ophthalmic and systemic agents in dry eye disease".
733:
3739:
14853:
14733:
14556:
14451:
14426:
14366:
13414:
13404:
13394:
12929:
12914:
12904:
12802:
12547:
12522:
12476:
12083:
11823:
11743:
11082:
10487:
10453:
9101:
9020:
8629:
8348:
8031:
7819:
7668:
7653:
7613:
7578:
7442:
7186:
7146:
7126:
7116:
7026:
6474:
4959:
1163:, liver dysfunction, blood disorders, or seizures. Systemic use of ketotifen may interact with other drugs that cause sedation, such as
13338:
12909:
12542:
12537:
12364:
11707:
10983:
10292:
9146:
9136:
8639:
7789:
7402:
3193:"Ketotifen - Mechanism, Indication, Contraindications, Dosing, Adverse Effect, Interaction, Hepatic Dose; Drug Index; Pediatric Oncall"
1179:. Systemic use of ketotifen may affect the results of some laboratory tests, such as skin tests for allergies or blood glucose levels.
1072:
in children under three years of age, whereas drug-eluting contact lenses are not recommended for children under eleven years of age.
13424:
13419:
12841:
8303:
8298:
8293:
7784:
7779:
5772:"In Vitro Assessment of the Antiviral Activity of Ketotifen, Indomethacin and Naproxen, Alone and in Combination, against SARS-CoV-2"
5520:
5468:
5416:
3326:
3060:
Castillo JG, Gamboa PM, García BE, Oehling A (1990). "Effect of ketotifen on phosphodiesterase activity from asthmatic individuals".
824:
such as asthma attacks and allergic reactions. In addition to treating allergies, ketotifen has shown efficacy in managing systemic
13619:
11398:
10782:
9939:
8000:
5844:
5745:
2642:
14926:
13579:
11410:
10794:
9951:
8549:
3196:
2705:
2185:
García-Martín E, Canto G, Agúndez JA (November 2013). "Metabolic considerations of drugs in the treatment of allergic diseases".
5303:
5222:
4454:
2058:
2027:
1922:
1824:
properties. One proposed mechanism of the increase in appetite involves the inhibitory effect of ketotifen on the production of
1537:
in the liver. The CYP enzymes are responsible for the oxidation and demethylation of ketotifen, producing the major metabolites
1409:. By preventing the degranulation of mast cells, ketotifen inhibits the release of inflammatory mediators such as histamine and
13606:
13597:
8024:
8005:
6467:
4615:
Pinke KH, Zorzella-Pezavento SF, de Campos Fraga-Silva TF, Mimura LA, de
Oliveira LR, Ishikawa LL, et al. (January 2020).
14956:
13588:
5442:
5281:
4953:
4912:
4426:
4245:
3983:
3954:
3876:
2955:
5192:
3713:
3170:
1039:
The mean elimination half-life of oral ketotifen is 12 hours. Besides its anti-histaminic activity, it is also a functional
14916:
13663:
10147:
3299:
13610:
11358:
11231:
9885:
9745:
7494:
6534:
14901:
6074:
4002:
Li L, Liu R, Peng C, Chen X, Li J (July 2022). "Pharmacogenomics for the efficacy and side effects of antihistamines".
3361:
Le Blaye I, Donatini B, Hall M, Krupp P (1992). "Acute ketotifen overdosage. A review of present clinical experience".
11324:
11316:
11249:
10737:
10729:
9838:
9830:
9763:
6084:
3617:
1429:
1413:, which are implicated in allergic reactions. Ketotifen action is also based on its inhibition of serotonin release.
946:
Ketotifen ophthalmic solution (eye drops) relieves and prevents eye itchiness and/or irritation associated with most
783:
761:
InChI=1S/C19H19NOS/c1-20-9-6-13(7-10-20)18-15-5-3-2-4-14(15)12-17(21)19-16(18)8-11-22-19/h2-5,8,11H,6-7,9-10,12H2,1H3
753:
128:
5019:
1809:
Different studies have shown conflicting results about the amount of weight gain caused by ketotifen. In one study (
14951:
14906:
11312:
10725:
9826:
4989:
1872:
Ketotifen is currently researched in context of a possible link between abnormalities in intestinal mast cells and
11479:
11374:
11320:
10808:
10733:
10022:
9901:
9834:
8898:
5124:
2971:
Sasaki F, Yokomizo T (August 2019). "The leukotriene receptors as therapeutic targets of inflammatory diseases".
339:
224:
109:
14911:
13628:
1716:
There was a litigation related to ketotifen. In 2021, the plaintiff, Edward C. Hanks, brought an action in the
1052:
1048:
176:
5634:
2665:"Acuvue Theravision with ketotifen (etafilcon A drug-eluting contact lens with ketotifen), for ophthalmic use"
2664:
430:
11402:
10786:
9943:
986:
833:
14946:
14931:
13570:
12766:
12092:
11378:
9905:
7995:
5837:
5094:
4763:
Slater JW, Zechnich AD, Haxby DG (January 1999). "Second-generation antihistamines: a comparative review".
2886:"Mast cell stabilizer ketotifen reduces hyperalgesia in a rodent model of surgically induced endometriosis"
1364:
1022:
648:
497:
1987:
1955:
1655:
Ketotifen was patented in 1970 and came into medical use in 1976. Ketotifen was developed and patented by
1503:, which are involved in the inflammatory response and tissue damage in allergic and respiratory diseases.
12058:
11471:
11362:
11007:
10358:
9889:
9151:
8857:
8353:
4179:"The effect of ketotifen on inflammatory markers in allergic conjunctivitis: an open, uncontrolled study"
1044:
888:
609:
5491:"Emergo finds midstage success in developing flu-fighter norketotifen + | Bioworld | BioWorld"
4177:
Martín AP, Urrets-Zavalia J, Berra A, Mariani AL, Gallino N, Gomez Demel E, et al. (January 2003).
1302:, and death. The risk of seizures is higher in children, especially those with a history of epilepsy or
14871:
13439:
13014:
12277:
11853:
11445:
11102:
10507:
9996:
7275:
5980:
5705:
Klooker TK, Braak B, Koopman KE, Welting O, Wouters MM, van der Heide S, et al. (September 2010).
1810:
978:
598:
64:
5043:
2490:"Successful use of montelukast in eosinophilic gastroenteritis: a case report and a literature review"
1864:
oil may prevent weight-gain induced by ketotifen, but, this has not been confirmed on human subjects.
590:
14936:
3492:"Ketotifen overdose. Toxic encephalopathy, epilepsy and mental retardation in an infant: case report"
3491:
3289:
2734:
1767:
1511:
1103:
1026:
5457:
3218:
Waterfield J (29 September 2013). "Antihistamines: Mode of action, prescribing rationale and uses".
2791:"Ketotifen alone or as additional medication for long-term control of asthma and wheeze in children"
2763:
14168:
13763:
13656:
13461:
13028:
12320:
12106:
11898:
10537:
7305:
6776:
6270:
5998:
5951:
5431:
1873:
1720:, against the defendants, Ned Hubbard and others, alleging that they violated his rights under the
1688:
In 2021, it was the 301st most commonly prescribed medication in the United States, with more than
625:
5597:
Asnaashari S, Delazar A, Habibi B, Vasfi R, Nahar L, Hamedeyazdan S, et al. (December 2010).
14941:
14654:
13208:
12774:
12611:
12096:
11518:
10837:
10686:
10051:
9226:
8911:
8452:
6566:
5830:
5439:"Efficacy and Safety of Norketotifen in Uncomplicated Influenza-like Illness: Influenza Clinical"
1644:
1610:
pharmacological properties, and side effect profiles of an antihistamine drug. First-generation H
1460:
962:
928:
165:
50:
5018:. Bethesda MD, US: National Center for Advancing Translational Sciences (NCATS). 12 April 2024.
3894:"Mast Cell Stabilizer (Ketotifen) in Fibromyalgia: Phase 1 Randomized Controlled Clinical Trial"
2233:"Topical ketotifen treatment for allergic conjunctivitis: a systematic review and Meta-analysis"
1238:, hyperexcitability (particularly in children), reversible coma, unusual tiredness or weakness,
13743:
13237:
13204:
12846:
12762:
12607:
12164:
12088:
12034:
11597:
11534:
11510:
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10899:
10861:
10829:
10804:
10152:
10067:
10043:
9791:
9580:
9435:
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9238:
9218:
8919:
8903:
8531:
8468:
8448:
8137:
7196:
3864:
3735:
3245:
Chaplin S, Scadding G (13 June 2011). "Antihistamines: Their properties and use in hay fever".
1656:
1092:
880:
296:
4941:
4617:"Calming Down Mast Cells with Ketotifen: A Potential Strategy for Multiple Sclerosis Therapy?"
4039:"Platelet-Activating Factor (PAF) in Allergic Rhinitis: Clinical and Therapeutic Implications"
4037:
Muñoz-Cano RM, Casas-Saucedo R, Valero
Santiago A, Bobolea I, Ribó P, Mullol J (August 2019).
3971:
911:
Ketotifen, an antihistamine medication and a mast cell stabilizer, is most commonly sold as a
570:
562:
13870:
13738:
13479:
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11125:
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10047:
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3942:
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1084:
1011:
974:
856:
486:
421:
263:
1623:-based compound with chemical structures similar to first-generation antihistamines such as
14921:
14110:
4228:
Stone M, Francisco JC, Kumar NN, Barboza J (1 January 2014). "Oral Mast Cell
Stabilizers".
1892:, but there were no studies to confirm the hypothesis; the research did not proceed behind
1798:
The underlying mechanisms of why ketotifen (similarly to other antihistamine drugs such as
1603:
1507:
1406:
1258:. The gastrointestinal effects may include nausea, vomiting, abdominal pain, diarrhea, and
1018:
and mast cell stabilizing properties persist even if administered for 12 months or longer.
801:
514:
506:
377:
369:
318:
5516:
5464:
5412:
2401:"The relation between antihistamine medication during early pregnancy & birth defects"
1806:) may increase appetite and lead to weight gain in some people, are not fully understood.
478:
87:
8:
13703:
13649:
13212:
12778:
12718:
12406:
12022:
11243:
11223:
10841:
10751:
9757:
9737:
9584:
9234:
8915:
8460:
6706:
6519:
6202:
6080:
1861:
1546:
1545:. Norketotifen is pharmacologically active and has a similar potency as ketotifen, while
1542:
1380:
1320:
1263:
935:
652:
629:
360:
172:
5706:
4521:
Sarcina D, Giovannini M, Oranges T, Barni S, Pedaci FA, Liccioli G, et al. (2021).
13543:
13101:
12681:
12373:
11538:
10931:
10865:
10071:
8050:
6771:
6701:
6493:
6490:
6193:
6070:
5798:
5737:
5682:
5657:
5626:
5599:"Essential oil from Citrus aurantifolia prevents ketotifen-induced weight-gain in mice"
5571:
5546:
5394:
4904:
4835:
4788:
4732:
4689:
4641:
4616:
4597:
4549:
4418:
4286:
4151:
4065:
3918:
3893:
3840:
3437:
3412:
3386:
3105:
3088:
3034:
2912:
2863:
2815:
2790:
2622:
2564:
2516:
2465:
2376:
2351:
2312:
2259:
2210:
2162:
2116:
1821:
1164:
1125:
821:
817:
139:
4205:
3660:
3192:
2701:
13795:
13713:
13330:
13220:
12722:
11967:
11526:
11342:
11193:
10853:
10763:
10755:
10639:
10461:
10059:
9909:
9697:
9538:
9484:
9118:
8843:
8835:
8570:
8476:
8274:
8258:
8111:
7906:
7257:
5803:
5729:
5687:
5618:
5576:
5398:
5386:
5214:
5064:
4949:
4908:
4892:
4873:
4839:
4827:
4780:
4776:
4736:
4724:
4693:
4681:
4646:
4589:
4554:
4503:
4499:
4422:
4406:
4387:
4327:
4322:
4305:
4278:
4241:
4210:
4156:
4105:
4070:
4019:
3979:
3950:
3923:
3872:
3845:
3787:
3691:
3664:
3511:
3507:
3476:
3442:
3378:
3374:
3281:
3110:
3069:
3039:
2988:
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2917:
2855:
2820:
2603:
2556:
2521:
2470:
2381:
2304:
2300:
2264:
2202:
2167:
2120:
2108:
2104:
2019:
1889:
1774:
1620:
1574:
1267:
1102:
The use of ketotifen eye drops during pregnancy and lactation is considered safe, as
1096:
970:
966:
958:
841:
825:
250:
238:
101:
5741:
4792:
4601:
4290:
3736:"Ketotifen Ophthalmic: Generic, Uses, Side Effects, Dosages, Interactions, Warnings"
3611:"Tablets, 1 mg ketotifen (as ketotifen hydrogen fumarate), Oral (product monograph)"
3390:
2867:
2316:
2214:
840:
throughout the body. Ketotifen is also used for other allergic-type conditions like
410:
14571:
14536:
12232:
12054:
11467:
10706:
10690:
10676:
10579:
10403:
10014:
7383:
7250:
6866:
6726:
6646:
6413:
6115:
5957:
5937:
5793:
5783:
5721:
5677:
5669:
5630:
5610:
5566:
5558:
5378:
5056:
4900:
4865:
4856:
Aelony Y (September 1998). "First-generation vs second-generation antihistamines".
4819:
4772:
4716:
4673:
4636:
4628:
4581:
4544:
4534:
4495:
4414:
4358:
4317:
4270:
4233:
4200:
4190:
4146:
4136:
4097:
4060:
4050:
4011:
3913:
3905:
3835:
3825:
3777:
3656:
3554:
3503:
3472:
3432:
3424:
3370:
3254:
3227:
3141:
3100:
3029:
3019:
2980:
2943:
2907:
2897:
2847:
2810:
2806:
2802:
2634:
2595:
2568:
2548:
2511:
2501:
2460:
2450:
2439:"A Summary of the New International EAACI/GA(2)LEN/EDF/WAO Guidelines in Urticaria"
2412:
2371:
2363:
2296:
2254:
2244:
2194:
2157:
2147:
2100:
1679:
A generic formulation of ketotifen marketed under the Ketotifen Sopharma brand name
1632:
1595:
1522:
1438:
1287:
912:
665:
278:
207:
197:
5438:
5277:
4823:
4614:
4237:
2947:
14885:
14753:
14689:
14649:
14606:
14601:
14411:
14311:
14173:
13723:
13491:
12566:
12045:
11175:
10710:
10698:
10658:
10603:
10254:
9807:
9636:
9498:
9387:
9073:
8774:
8070:
6786:
6746:
6721:
6606:
6428:
6140:
6060:
5947:
5916:
5184:
4869:
4677:
4274:
3909:
3709:
3231:
3166:
2198:
1636:
1550:
1530:
1446:
1421:
1387:
1303:
1255:
1176:
1076:
1006:
402:
306:
286:
11253:
9767:
8016:
6459:
2417:
2400:
1029:
for adult use. In the UK, ketotifen is available as tables and elixir (liquid).
14778:
14631:
14621:
14521:
14306:
14266:
14133:
13930:
13850:
13758:
13718:
13680:
13487:
13483:
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13054:
12696:
12617:
12441:
12388:
12030:
12004:
11994:
11986:
11916:
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11129:
10957:
10551:
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8058:
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6013:
5483:
4632:
4363:
4346:
3295:
3275:
3146:
3129:
2506:
2489:
2367:
2352:"Ketotifen in the management of chronic urticaria: resurrection of an old drug"
2334:. American Academy of Allergy, Asthma & Immunology Annual Meeting. Houston.
1841:
1628:
1247:
1239:
1220:
1172:
1033:
849:
805:
23:, a nonsteroidal anti-inflammatory drug with analgesic and antipyretic effects.
5517:"Norketotifen in Influenza -Like Illness - Clinical Trials Registry - ICH GCP"
4539:
4522:
3558:
3428:
3024:
3007:
2552:
2455:
2438:
942:
attacks or anaphylaxis, as well as various mast cell, allergic-type disorders.
14895:
14674:
14669:
14664:
14639:
14576:
14561:
14258:
14148:
14065:
14030:
14010:
13855:
13790:
13733:
13698:
13465:
13322:
13253:
13083:
13044:
13032:
12324:
12272:
12222:
11906:
11902:
11865:
11848:
11703:
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10975:
10915:
10541:
10519:
10477:
10378:
10172:
10125:
9861:
9530:
9110:
8831:
8566:
8250:
8149:
8123:
8047:
7349:
7345:
7309:
7269:
7212:
7208:
7071:
7021:
6911:
6896:
6821:
6816:
6621:
6383:
6255:
6232:
6211:
6173:
6168:
6120:
5932:
5866:
5853:
5465:"Efficacy and Safety of Norketotifen in Uncomplicated Influenza-like Illness"
4141:
4124:
4036:
1992:
1960:
1853:
1832:
that plays a role in regulating energy metabolism. TNF-α can act directly on
1762:
1675:
1480:
1472:
1456:
1383:
1338:
1331:
1196:
1129:
1060:
924:
876:
864:
797:
641:
458:
5770:
Kiani P, Scholey A, Dahl TA, McMann L, Iversen JM, Verster JC (March 2021).
5725:
3764:
Kakiuchi M, Ohashi T, Musoh K, Kawamura K, Morikawa K, Kato H (April 1997).
2984:
2286:
2249:
2232:
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13139:
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12746:
12671:
12638:
12456:
12338:
12252:
12100:
11932:
11768:
11763:
11723:
11675:
11629:
11613:
11463:
11257:
11057:
10907:
10767:
10702:
10609:
10595:
10567:
10555:
10497:
10448:
10438:
10408:
10388:
10363:
10308:
10279:
10269:
10224:
10192:
10180:
10176:
10160:
10105:
9771:
9691:
9541:
9414:
9212:
9196:
9130:
8946:
8925:
8892:
8847:
8709:
8654:
8554:
8278:
8195:
8141:
8131:
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7869:
7809:
7730:
7603:
7387:
7379:
7371:
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7353:
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7228:
7200:
7066:
7051:
6936:
6926:
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6916:
6891:
6886:
6856:
6836:
6826:
6791:
6741:
6671:
6591:
6448:
6438:
6348:
6328:
6317:
6295:
6285:
6275:
6130:
6035:
5985:
5972:
5857:
5807:
5733:
5691:
5622:
5580:
5390:
5060:
4831:
4728:
4685:
4650:
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4558:
4391:
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4160:
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3927:
3849:
3515:
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3114:
3043:
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2851:
2824:
2599:
2560:
2525:
2474:
2385:
2308:
2268:
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2171:
1845:
1743:
1538:
1291:
1259:
1056:
1002:
982:
916:
829:
202:
192:
5068:
4877:
4784:
4507:
4195:
4178:
4109:
3791:
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3668:
3610:
3446:
3382:
3073:
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2607:
2112:
29:
14848:
14818:
14803:
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14511:
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14228:
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14055:
14035:
14000:
13990:
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13970:
13955:
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13885:
13865:
13830:
13455:
13447:
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13350:
13346:
13326:
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13305:
13285:
13273:
13257:
13241:
13079:
13009:
12954:
12924:
12870:
12858:
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12738:
12667:
12588:
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12328:
12305:
12300:
12289:
12247:
12227:
12202:
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12149:
11963:
11928:
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11843:
11793:
11783:
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11690:
11645:
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10894:
10798:
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10457:
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10413:
10393:
10328:
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10304:
10300:
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10200:
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10115:
9955:
9873:
9865:
9683:
9679:
9574:
9570:
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9355:
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9278:
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9200:
9188:
9180:
9114:
9054:
9050:
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8970:
8888:
8880:
8822:
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8759:
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8634:
8623:
8594:
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8535:
8393:
8383:
8323:
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8241:
8236:
8216:
8191:
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7854:
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7583:
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7141:
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7096:
6981:
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6906:
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6801:
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6761:
6756:
6751:
6716:
6666:
6661:
6651:
6596:
6571:
6539:
6524:
6423:
6353:
6338:
6333:
6313:
6290:
6280:
6265:
6260:
6178:
6125:
6110:
6100:
6090:
6040:
6025:
5990:
5901:
5562:
5011:
2583:
2152:
2135:
1476:
1410:
1394:
1360:
counts in patients who are concurrently taking oral antidiabetic agents.
1357:
1327:
1251:
1231:
1227:
1160:
1148:
1040:
990:
884:
872:
868:
95:
5658:"Mast Cells and Irritable Bowel Syndrome: From the Bench to the Bedside"
4981:
4404:
3830:
3814:"Tryptase and Exogenous Trypsin: Mechanisms and Ophthalmic Applications"
3813:
3490:
Yokoyama H, Hirose M, Uematsu M, Haginoya K, Iinuma K, Kimura S (2012).
3121:
2902:
2885:
450:
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14828:
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11753:
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10987:
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9192:
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7001:
6961:
6956:
6881:
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6731:
6696:
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6443:
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4101:
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2638:
1885:
1803:
1799:
1782:
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1500:
1492:
1350:
1295:
1283:
1235:
1216:
1144:
994:
695:
469:
20:
5788:
5771:
5547:"Impact of caffeine on weight changes due to ketotifen administration"
5382:
4720:
4015:
2657:
1561:
14833:
14798:
14793:
14783:
14748:
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11803:
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10962:
10923:
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10849:
10824:
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10814:
10771:
10716:
10619:
10599:
10591:
10587:
10527:
10511:
10481:
10418:
10383:
10353:
10208:
10188:
10164:
10141:
10055:
10028:
10018:
10004:
9976:
9971:
9924:
9913:
9844:
9812:
9802:
9779:
9775:
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9749:
9741:
9687:
9675:
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9606:
9557:
9552:
9516:
9420:
9405:
9372:
9334:
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9314:
9309:
9304:
9299:
9294:
9284:
9269:
9259:
9166:
9096:
9030:
9025:
9015:
9005:
8995:
8980:
8954:
8867:
8862:
8851:
8817:
8704:
8699:
8649:
8604:
8586:
8562:
8515:
8464:
8456:
8433:
8428:
8408:
8403:
8398:
8363:
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8282:
8231:
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8211:
8206:
8179:
8175:
8157:
8145:
8119:
8088:
7955:
7916:
7864:
7814:
7715:
7593:
7489:
7474:
7337:
7325:
7291:
7279:
7265:
7216:
7204:
7166:
7156:
7106:
7011:
6986:
6901:
6876:
6851:
6841:
6831:
6796:
6736:
6676:
6611:
6601:
6581:
6529:
6377:
6343:
6217:
6050:
6045:
6030:
6003:
5927:
5906:
5891:
5673:
5614:
5246:"What To Know About Ketotifen (popular Brands: Ketasma And Asthafen)"
4585:
1849:
1833:
1817:
1754:
1640:
1624:
1616:
1570:
1566:
1488:
1391:
1346:
1342:
1271:
1212:
1208:
1156:
1152:
1112:
998:
927:
form (eye drops or drug-eluting contact lenses), it is used to treat
896:
837:
813:
388:
81:
4125:"Eosinophil recruitment and activation: the role of lipid mediators"
3682:
Rogóz Z, Skuza G, Sowińska H (1981). "Central action of ketotifen".
3258:
2884:
Zhu TH, Zou G, Ding SJ, Li TT, Zhu LB, Wang JZ, et al. (2019).
14823:
14616:
14501:
14416:
13995:
13980:
13965:
13950:
13688:
13529:
13525:
13503:
13499:
13310:
13289:
13154:
13075:
13058:
12752:
12730:
12714:
12663:
12584:
12314:
12207:
12128:
12078:
12068:
11959:
11924:
11920:
11888:
11695:
11649:
11542:
11354:
11330:
11283:
11156:
10979:
10967:
10869:
10743:
10694:
10681:
10635:
10571:
10563:
10492:
10284:
10264:
10248:
10110:
10075:
9881:
9849:
9797:
9727:
9663:
9659:
9534:
9526:
9480:
9472:
9410:
9368:
9364:
9360:
9274:
9171:
9141:
9106:
9058:
9046:
8985:
8827:
8807:
8802:
8755:
8619:
8609:
8590:
8500:
8490:
8480:
8413:
8333:
8313:
8288:
8266:
8246:
8226:
8187:
7975:
7934:
7874:
7769:
7764:
7748:
7484:
7479:
7375:
7283:
7244:
7031:
6586:
6403:
6105:
5967:
5598:
4985:
1894:
1857:
1829:
1747:
1729:, which affirmed the district court's judgment on 7 February 2022.
1660:
1529:
Ketotifen, like other antihistamines, is mainly metabolized by the
1496:
1484:
1475:
and release of histamine and other inflammatory mediators, such as
1275:
1195:. Other symptoms may include confusion, disorientation, agitation,
1192:
1080:
947:
900:
542:
534:
441:
123:
3576:"Ketotifen 2mg Tablets, 1mg/5mL Oral Solution (product monograph)"
3280:. National Institute of Child Health and Human Development. 2006.
1825:
1770:
1047:(a medication that blocks the enzymes that regulate the levels of
718:
14461:
13895:
13300:
13194:
13149:
13040:
12899:
12894:
12889:
12884:
12810:
12295:
12159:
12118:
11883:
11808:
11561:
11370:
11217:
11135:
10443:
10373:
10343:
9897:
9732:
9721:
9655:
9562:
9425:
9176:
8872:
8684:
8674:
8664:
8423:
8418:
8308:
7774:
7725:
7512:
7329:
6547:
6433:
6394:
6309:
5095:"Drug Approval Package: Zaditor (Ketotifen Fumarate) NDA# 21-066"
4455:"Center for drug evaluation and research. Application no. 21-066"
1778:
1718:
United States District Court for the Central District of Illinois
1137:
5296:
4405:
Lieberman P, Hernandez-Trujillo V, Lieberman J, Frew AJ (2008).
4176:
3413:"Ketotifen overdose: surveillance of the toxicity of a new drug"
2789:
Schwarzer G, Bassler D, Mitra A, Ducharme FM, Forster J (2004).
1777:
activity. Thus, ketotifen can probably be considered a sedating
13174:
12964:
12790:
12786:
12527:
11571:
11420:
11346:
11334:
11213:
11209:
10038:
9961:
9869:
9857:
9853:
9817:
9717:
9713:
8714:
7929:
7720:
4377:
1837:
1742:
Research directions for ketotifen include the investigation of
1534:
1515:
1279:
1204:
1200:
1168:
939:
845:
809:
581:
4347:"Analysis for commonly prescribed non-sedating antihistamines"
3865:"Antihistamines and Related Antiallergic and Antiulcer Agents"
3005:
2720:
1506:
Ketotifen has a dual mode of action as an antihistamine and a
1250:. The respiratory effects may include respiratory depression,
13641:
13169:
13164:
12411:
12332:
10033:
9986:
8368:
4520:
3605:
3603:
3570:
3568:
3489:
2788:
1751:
1705:
1191:
The most common symptom of ketotifen overdose is significant
1133:
1005:
that react to allergens, therefore, ketotifen, by blocking a
836:(MCAS), which involve abnormal accumulation or activation of
709:
553:
311:
5596:
5544:
4122:
3134:
Continuing Education in Anaesthesia Critical Care & Pain
3130:"Phosphodiesterase inhibitors and the cardiovascular system"
3006:
Mostafa GA, Bakheit A, AlMasoud N, AlRabiah H (April 2021).
2332:
Ketotifen: A Role in the Treatment of Idiopathic Anaphylaxis
1884:
It was hypothesized that ketotifen may be effective against
1844:
and acts as a satiety signal by binding to receptors in the
1639:, and other compounds with antihistamine properties such as
1363:
Systemic use of ketotifen may decrease the effectiveness of
1323:, antihistamines, and medications with sedative properties.
614:
37:
14808:
12798:
11406:
11205:
11201:
11197:
10790:
9947:
9709:
9705:
9701:
8669:
5368:
4706:
4344:
3763:
3059:
1471:
Ketotifen acts as a mast cell stabilizer by preventing the
1299:
1294:. The neurologic effects of ketotifen overdose may include
525:
5704:
5125:"Drug Approval Package: Acuvue Theravision with ketotifen"
4808:
4227:
3647:
Greenwood C (July 1982). "The pharmacology of ketotifen".
3600:
3565:
2837:
2696:
2694:
2692:
1491:. Ketotifen also inhibits the activation and migration of
1124:
Common side effects of ophthalmic use are eye redness and
13158:
12734:
12596:
11366:
11308:
10721:
9893:
9822:
9126:
8270:
5509:
5250:
4571:
3360:
2184:
1430:
3978:. Springer Science & Business Media. pp. 282–.
3462:
3460:
3458:
3456:
2702:"Ketotifen ophthalmic Uses, Side Effects & Warnings"
2487:
2350:
Sokol KC, Amar NK, Starkey J, Grant JA (December 2013).
1109:
National Institute of Child Health and Human Development
863:, which are found on various cells in the body, such as
5322:
5207:
5117:
5087:
4485:
4087:
3702:
2689:
2539:
Frieri M (June 2018). "Mast Cell Activation Syndrome".
2282:
2280:
2278:
883:, which blocks inflammation-causing chemicals known as
5769:
5405:
4345:
El-Kommos ME, El-Gizawy SM, Atia NN, Hosny NM (2015).
3321:
3319:
3317:
1727:
United States Court of Appeals for the Seventh Circuit
1590:
receptors, thereby exerting its antihistamine effects.
1549:
is inactive. The metabolites are then conjugated with
14869:
4890:
4663:
3871:. Lippincott Williams & Wilkins. pp. 1019–.
3538:
3453:
2756:
2349:
1793:
919:, ketotifen fumarate, and is available in two forms:
5270:
3161:
3159:
3157:
2275:
2090:
954:
lenses, and have less than 1 degree of astigmatism.
5545:Habibi Asl B, Vaez H, Imankhah T, Hamidi S (2014).
5306:. National Institutes of Health. 15 December 2023.
4762:
3314:
3185:
2488:El-Alali EA, Abukhiran IM, Alhmoud TZ (July 2021).
2020:"Zaditen Summary of Product Characteristics (SmPC)"
1917:
1915:
1913:
1911:
1514:and airway inflammation that are characteristic of
1230:(fast, pounding, or irregular heartbeat or pulse),
429:
5042:
5004:
4666:Current Opinion in Allergy and Clinical Immunology
3681:
2728:"List of nationally authorised medicinal products"
1852:regulation could be involved in central serotonin
1722:Eighth Amendment to the United States Constitution
1334:, which may decrease the activities of ketotifen.
8046:
6489:
5304:"DailyMed - ZADITOR- ketotifen fumarate solution"
3891:
3856:
3154:
1226:Other symptoms of ketotifen overdose may include
14893:
4306:"Standard treatment: the role of antihistamines"
4123:Luna-Gomes T, Bozza PT, Bandeira-Melo C (2013).
1908:
1553:or sulfate and excreted in the urine and feces.
1242:, dizziness or fainting, loss of consciousness.
993:. Ketotifen has also shown efficacy in managing
409:
401:
5592:
5590:
5540:
5538:
4804:
4802:
4447:
4260:
4172:
4170:
3997:
3995:
3976:Immunopharmacology: Principles and Perspectives
3947:Textbook of Medicinal Chemistry Vol II - E-Book
3892:Ang DC, Hilligoss J, Stump T (September 2015).
3812:Ma C, Li H, Lu S, Li X, Wang S, Wang W (2023).
3807:
3805:
3803:
3801:
3728:
3710:"Ketotifen (Oral) Advanced Patient Information"
3270:
3268:
3244:
2879:
2877:
2432:
2430:
2428:
2398:
2345:
2343:
2341:
2053:
2051:
2049:
2047:
2045:
1950:
1948:
938:form (tablets or syrup), it is used to prevent
376:
368:
5348:
4851:
4849:
4758:
4756:
4754:
4752:
4750:
4748:
4746:
4709:International Forum of Allergy & Rhinology
4398:
4338:
3934:
3759:
3757:
3642:
3640:
3638:
3410:
3406:
3404:
3402:
3400:
3356:
3354:
3352:
3055:
3053:
2970:
2226:
2224:
347:4-(1-Methylpiperidin-4-ylidene)-4,9-dihydro-10
13657:
10454:Serotonin antagonists and reuptake inhibitors
8032:
6475:
5838:
5763:
5698:
5662:Journal of Neurogastroenterology and Motility
5177:
4974:
4001:
2323:
2086:
2084:
2082:
2080:
2078:
2076:
1816:Ketotifen exhibits a chemical resemblance to
5655:
5649:
5587:
5535:
5362:
5147:
4939:
4884:
4799:
4700:
4657:
4608:
4565:
4514:
4371:
4297:
4254:
4167:
4116:
4030:
3992:
3885:
3798:
3483:
3265:
3080:
2999:
2964:
2883:
2874:
2782:
2532:
2481:
2425:
2338:
2042:
1945:
1143:Side effects of systemic (oral) use include
989:(MCAS), as well as allergic and nonallergic
127:
5034:
4846:
4743:
4479:
4081:
3754:
3684:Polish Journal of Pharmacology and Pharmacy
3675:
3635:
3397:
3349:
3086:
3050:
2831:
2392:
2221:
2178:
2127:
1867:
1708:, a Swiss-American pharmaceutical company.
1337:The concomitant use of oral ketotifen with
1203:(impairment of voluntary muscle movement),
13664:
13650:
8039:
8025:
6482:
6468:
5845:
5831:
4221:
3949:. Elsevier Health Sciences. pp. 38–.
3940:
3217:
2620:
2405:Egyptian Journal of Medical Human Genetics
2356:Annals of Allergy, Asthma & Immunology
2329:
2133:
2073:
2012:
1207:(involuntary regular muscle contraction),
1116:sufficient safety data becomes available.
804:used to treat allergic conditions such as
651:
628:
485:
477:
5797:
5787:
5681:
5570:
5040:
4891:Chiriac AM, Bousquet J, Demoly P (2017).
4640:
4548:
4538:
4362:
4321:
4204:
4194:
4150:
4140:
4064:
4054:
3963:
3917:
3839:
3829:
3781:
3646:
3436:
3145:
3104:
3033:
3023:
2931:
2911:
2901:
2814:
2581:
2515:
2505:
2464:
2454:
2436:
2416:
2375:
2258:
2248:
2161:
2151:
1980:
1435:Tooltip muscarinic acetylcholine receptor
1151:(5.0–5.4 kilograms (11.0–11.9 lb)),
1083:(a disorder causing recurrent seizures),
513:
505:
5852:
3869:Foye's Principles of Medicinal Chemistry
3811:
2230:
1674:
1560:
1211:(involuntary, irregular muscle twitch),
957:Oral ketotifen is used to treat asthma,
879:activity, ketotifen also functions as a
741:O=C3c1sccc1C(\c2c(cccc2)C3)=C4/CCN(C)CC4
4933:
3972:"Substances with an Antialergic Effect"
3167:"Ketotifen Monograph for Professionals"
3089:"Overview of PDEs and their regulation"
2840:Biopharmaceutics & Drug Disposition
1836:(fat cells) to regulate the release of
1781:that is converted to NK, a nonsedating
624:
457:
449:
100:
14894:
4948:. John Wiley & Sons. p. 548.
4855:
4574:Environmental Toxicology and Chemistry
3862:
3127:
2764:"Ketotifen Update (4th December 2019)"
2538:
2443:The World Allergy Organization Journal
1923:"Zaditor- ketotifen fumarate solution"
1876:, but there are no solid results yet.
1670:
1278:. The hematologic effects may include
981:, systemic mast cell diseases such as
891:that regulates blood vessel dilation.
642:
244:
13645:
8020:
6463:
5871:
5826:
5656:Zhang L, Song J, Hou X (April 2016).
4921:from the original on 24 February 2024
4467:from the original on 14 February 2024
4435:from the original on 24 February 2024
3969:
3742:from the original on 24 February 2024
3623:from the original on 21 February 2024
3199:from the original on 16 November 2023
2770:from the original on 29 November 2023
2708:from the original on 16 November 2023
2330:Li Z, Celestin J (23 February 2015).
2069:from the original on 3 December 2023.
597:
589:
569:
561:
257:
118:
86:
68:
11968:methylergometrine (methylergonovine)
10928:N-desalkylquetiapine (norquetiapine)
10764:methylergometrine (methylergonovine)
9910:methylergometrine (methylergonovine)
9539:methylergometrine (methylergonovine)
9485:methylergometrine (methylergonovine)
8844:methylergometrine (methylergonovine)
8275:methylergometrine (methylergonovine)
5637:from the original on 28 January 2024
5243:
4962:from the original on 10 January 2023
4944:. In Fischer J, Ganellin CR (eds.).
4942:"Table of Selected Analogue Classes"
4303:
3716:from the original on 2 December 2023
3337:from the original on 25 October 2020
2937:
1066:
820:, while the oral form helps prevent
206:
196:
10932:N-desmethylclozapine (norclozapine)
5237:
5185:"Ketotifen - Drug Usage Statistics"
3867:. In Lemke TL, Williams DA (eds.).
3411:Jeffreys DB, Volans GN (May 1981).
3302:from the original on 3 October 2023
3087:Omori K, Kotera J (February 2007).
2940:Compendium of Inflammatory Diseases
2059:"Acuvue Theravision with ketotifen"
1055:, which are molecules that control
541:
533:
392:
13:
6747:Etybenzatropine (ethylbenztropine)
5523:from the original on 13 April 2024
5497:from the original on 13 April 2024
5471:from the original on 20 April 2024
5445:from the original on 13 April 2024
5419:from the original on 13 April 2024
5258:from the original on 13 April 2024
5225:from the original on 11 April 2021
5165:from the original on 11 March 2024
5135:from the original on 10 March 2024
5075:from the original on 13 April 2024
5022:from the original on 13 April 2024
4992:from the original on 6 August 2019
4905:10.1016/B978-0-323-37579-5.00005-2
4419:10.1016/B978-0-323-04404-2.10089-2
4230:Encyclopedia of Medical Immunology
3522:from the original on 13 April 2024
3106:10.1161/01.RES.0000256354.95791.f1
2744:from the original on 13 April 2024
2645:from the original on 6 August 2024
2030:from the original on 10 March 2024
2000:from the original on 10 March 2024
1968:from the original on 10 March 2024
1840:. Leptin is a hormone produced by
1794:Increased appetite and weight gain
1270:. The hepatic effects may include
895:medical conditions, such as acute
14:
14968:
14412:Levomepromazine/Methotrimeprazine
5818:
5751:from the original on 11 June 2021
5359: (C.D. Ill 8 March 2021).
5336:from the original on 13 July 2021
5310:from the original on 11 June 2021
5284:from the original on 2 April 2024
5105:from the original on 8 March 2024
4893:"Principles of Allergy Diagnosis"
3661:10.1378/chest.82.1_supplement.45s
3588:from the original on 18 July 2022
3173:from the original on 11 June 2021
2677:from the original on 8 March 2024
1933:from the original on 11 June 2021
1761:suggest that NK may be the major
1746:(NK), a metabolite of ketotifen.
1556:
1326:Oral ketotifen may interact with
1111:advises to apply pressure on the
973:(hives), cold-induced urticaria,
150:
14879:
14031:Nortriptyline (noramitriptyline)
5928:Bromazine (bromodiphenhydramine)
5551:Advanced Pharmaceutical Bulletin
5195:from the original on 4 June 2023
4777:10.2165/00003495-199957010-00004
4488:European Journal of Pharmacology
4380:J Investig Allergol Clin Immunol
4323:10.1046/j.0022-202x.2001.00032.x
3770:Japanese Journal of Pharmacology
3508:10.1111/j.1442-200X.2012.03718.x
3477:10.2165/00128415-199204220-00009
3375:10.2165/00002018-199207050-00007
3062:Allergologia et Immunopathologia
2399:Shawky RM, Seifeldin NS (2015).
2301:10.1111/j.1398-9995.2009.02178.x
2105:10.2165/00003495-199040030-00006
1420:In addition, ketotifen has weak
1262:. The renal effects may include
682:
676:
36:
13620:Monoamine metabolism modulators
8001:Monoamine metabolism modulators
5161:(Press release). 2 March 2022.
3238:
3211:
2938:Bäck M (2016). "Leukotrienes".
2614:
2575:
1737:
1573:(having three rings of atoms),
1374:
1313:
1215:(dysfunction of eye movement),
1119:
906:
855:Ketotifen acts by blocking the
816:and irritation associated with
771:Key:YNQQEYBLVYAWNX-WLHGVMLRSA-N
766:Key:ZCVMWBYGMWKGHF-UHFFFAOYSA-N
351:-benzocycloheptathiophen-10-one
14927:Serotonin receptor antagonists
13671:
6184:Tripelennamine (pyribenzamine)
4897:Middleton's Allergy Essentials
2807:10.1002/14651858.CD001384.pub2
2187:Expert Opin Drug Metab Toxicol
2134:Ono J, Toshida H (July 2022).
1698:
1155:, irritability, and increased
688:
685:
670:
233:
1:
13607:Monoamine reuptake inhibitors
13571:Receptor/signaling modulators
8006:Monoamine reuptake inhibitors
7996:Receptor/signaling modulators
4946:Analogue-based Drug Discovery
4858:Archives of Internal Medicine
4824:10.1080/15389588.2023.2265002
4351:Analytical Chemistry Research
4310:J Investig Dermatol Symp Proc
4238:10.1007/978-1-4614-9194-1_242
3941:Alagarsamy V (16 June 2012).
2948:10.1007/978-3-7643-8550-7_105
1988:"Zaditor Product information"
1956:"Zaditen Product information"
1901:
1788:
1711:
1531:cytochrome P450 (CYP) enzymes
987:mast cell activation syndrome
834:mast cell activation syndrome
179:, drug-eluting contact lenses
14957:Phosphodiesterase inhibitors
6058:Phenylpyridinylpropanamines:
5330:"Trademark search - ZADITOR"
4940:Alapi EM, Fischer J (2006).
4870:10.1001/archinte.158.17.1949
4678:10.1097/ACI.0000000000000773
4500:10.1016/0014-2999(92)90383-F
4275:10.3109/10837450.2013.800108
3910:10.1097/AJP.0000000000000169
3898:The Clinical Journal of Pain
3232:10.12968/npre.2009.7.4.41711
3128:Feneck R (1 December 2007).
2437:Zuberbier T (January 2012).
2199:10.1517/17425255.2013.823400
1820:, a substance known for its
1683:
1365:benzylpenicilloyl polylysine
1132:, eye discomfort, eye pain,
1023:Food and Drug Administration
7:
14917:Drugs developed by Novartis
13440:Tetracyclic antidepressants
13015:Tetracyclic antidepressants
12278:Tetracyclic antidepressants
11854:Tetracyclic antidepressants
11103:Tetracyclic antidepressants
10508:Tetracyclic antidepressants
7629:Quisultazine (quisultidine)
7276:Tetracyclic antidepressants
5981:Diphenylmethanolpiperidines
3970:Drews J (6 December 2012).
2627:Clinical Immunotherapeutics
2418:10.1016/j.ejmhg.2015.04.003
1879:
1732:
1182:
1045:phosphodiesterase inhibitor
889:phosphodiesterase inhibitor
10:
14973:
14297:Carfenazine (carphenazine)
6592:Benzatropine (benztropine)
5159:Johnson and Johnson Vision
5044:"An Overview of Ketotifen"
4633:10.1007/s13311-019-00775-8
4364:10.1016/j.ancr.2014.11.003
2795:Cochrane Database Syst Rev
2621:Markham A, Goa KL (1996).
2584:"An Overview of Ketotifen"
2507:10.1186/s12876-021-01854-x
2368:10.1016/j.anai.2013.10.003
1811:postmarketing surveillance
1650:
1089:pyloroduodenal obstruction
979:exercise-induced urticaria
660:Chemical and physical data
18:
14902:Benzocycloheptathiophenes
14711:
14688:
14630:
14257:
14109:
14026:Northiaden (nordosulepin)
13764:Tricyclic antidepressants
13757:
13679:
13561:
13518:
13462:Tricyclic antidepressants
13380:Metitepine (methiothepin)
13230:
13127:
13115:
13068:
13029:Tricyclic antidepressants
12960:Metitepine (methiothepin)
12834:
12707:
12695:
12644:Metitepine (methiothepin)
12626:
12577:
12565:
12510:
12399:
12387:
12357:
12137:
12015:
12003:
11985:
11947:
11899:Tricyclic antidepressants
11774:Metitepine (methiothepin)
11580:
11186:
11174:
11149:
11018:Metitepine (methiothepin)
10887:
10669:
10657:
10628:
10538:Tricyclic antidepressants
10369:Metitepine (methiothepin)
10093:
9647:
9635:
9623:
9602:Metitepine (methiothepin)
9594:
9509:
9497:
9465:
9457:Metitepine (methiothepin)
9449:
9398:
9386:
9348:
9320:Metitepine (methiothepin)
9252:
9084:
9072:
9039:
9011:Metitepine (methiothepin)
8934:
8785:
8773:
8738:
8660:Metitepine (methiothepin)
8524:
8081:
8069:
8057:
7988:
7943:
7899:
7887:
7757:
7698:
7686:
7521:
7467:
7455:
7306:Tricyclic antidepressants
7162:Sequifenadine (bicarphen)
6556:
6512:
6500:
6392:
6362:
6192:
6139:
5999:Diphenylmethylpiperazines
5925:Diarylmethoxyalkylamines:
5915:
5865:
5371:Drug Development Research
5215:"Ketotifen International"
4812:Traffic Injury Prevention
4540:10.3389/fimmu.2021.688364
4304:Merk HF (November 2001).
3559:10.1007/s40278-013-2459-5
3429:10.1136/bmj.282.6278.1755
3025:10.3390/molecules26072039
2735:European Medicines Agency
2553:10.1007/s12016-015-8487-6
2456:10.1186/1939-4551-5-S1-S1
1768:pro-inflammatory cytokine
1512:bronchial hyperreactivity
1027:European Medicines Agency
779:
749:
729:
707:
694:
664:
659:
640:
608:
580:
552:
524:
496:
468:
440:
420:
387:
359:
335:
330:
317:
305:
295:
285:
277:
223:
218:
183:
164:
138:
108:
94:
76:
59:
49:
44:
35:
14169:Hydroxyethylpromethazine
12950:Latrepirdine (dimebolin)
12639:Latrepirdine (dimebolin)
11964:ergometrine (ergonovine)
11764:Latrepirdine (dimebolin)
11161:ergometrine (ergonovine)
9874:ergometrine (ergonovine)
9477:ergometrine (ergonovine)
9055:ergometrine (ergonovine)
8760:ergometrine (ergonovine)
6944:Second/third-generation:
6777:Hydroxyethylpromethazine
6271:Hydroxyethylpromethazine
5278:"Ketotifen (Ingredient)"
4142:10.3389/fphar.2013.00027
3496:Pediatrics International
3147:10.1093/bjaceaccp/mkm039
2541:Clin Rev Allergy Immunol
2231:Dou XY, Zhang W (2023).
1874:irritable bowel syndrome
1868:Irritable bowel syndrome
1565:Chemical structure of a
1099:(inability to urinate).
1061:smooth muscle relaxation
19:Not to be confused with
16:Antihistamine medication
14952:Leukotriene antagonists
14907:H1 receptor antagonists
14655:Eslicarbazepine acetate
13861:Depramine (balipramine)
13238:Atypical antipsychotics
12847:Atypical antipsychotics
12165:Atypical antipsychotics
11598:Atypical antipsychotics
10900:Atypical antipsychotics
10153:Atypical antipsychotics
8532:Atypical antipsychotics
8138:Atypical antipsychotics
7584:Lavoltidine (loxtidine)
7197:Atypical antipsychotics
7142:Quifenadine (phencarol)
6807:Mepyramine (pyrilamine)
6567:4-Methyldiphenhydramine
6444:Mepyramine (pyrilamine)
6164:Mepyramine (pyrilamine)
5726:10.1136/gut.2010.213108
5332:. USPTO. 8 April 2024.
3417:British Medical Journal
3327:"Zaditen - MIMS online"
2250:10.18240/ijo.2023.02.17
1773:, suggesting potential
1405:= 0.166 nM) – and
963:allergic conjunctivitis
929:allergic conjunctivitis
55:Zaditor, Alaway, others
14557:Savoxepin/Cipazoxapine
13744:Pyridinobenzodiazepine
13480:Typical antipsychotics
13051:Typical antipsychotics
12311:Typical antipsychotics
12193:Bemesetron (MDL-72222)
11913:Typical antipsychotics
11126:Typical antipsychotics
10548:Typical antipsychotics
9239:5-(nonyloxy)tryptamine
7360:Typical antipsychotics
5244:Tata (28 March 2024).
5061:10.1378/chest.82.1.30S
4413:. pp. 1317–1329.
3545:"Ketotifen overdose".
2852:10.1002/bdd.2510130404
2600:10.1378/chest.82.1.30S
1680:
1657:Sandoz Pharmaceuticals
1591:
1353:, is not recommended.
1234:(low blood pressure),
1093:angle-closure glaucoma
881:leukotriene antagonist
14912:Mast cell stabilizers
13891:Dosulepin (dothiepin)
13876:Desmethyltrimipramine
13871:Desmethylclomipramine
13866:(desmethylimipramine)
13739:Pyridazinobenzoxazine
13629:Monoamine neurotoxins
11407:MDMA (midomafetamine)
10791:MDMA (midomafetamine)
10394:Opiranserin (VVZ-149)
9948:MDMA (midomafetamine)
9654:25H/NB series (e.g.,
7326:dosulepin (dothiepin)
5603:Phytotherapy Research
5131:. 19 September 2022.
4196:10.1186/1471-2415-3-2
2985:10.1093/intimm/dxz044
1888:, a virus behind the
1678:
1659:(currently a part of
1564:
1466:mucociliary clearance
1298:, hyperexcitability,
1085:prostatic hypertrophy
1057:blood vessel dilation
975:cholinergic urticaria
12101:bufotenidine (5-HTQ)
11224:5-Methoxytryptamines
9738:5-Methoxytryptamines
6203:Dibenzocycloheptenes
5563:10.5681/apb.2014.013
5101:. 20 November 2001.
5055:(1 Suppl): 30s–32s.
5041:MacDonald G (1982).
5012:"Ketotifen Fumarate"
4899:. pp. 117–131.
4232:. pp. 551–555.
3655:(1 Suppl): 45S–48S.
3195:. Pediatric Oncall.
2942:. pp. 849–857.
2594:(1 Suppl): 30s–32s.
2582:MacDonald G (1982).
2494:BMC Gastroenterology
2153:10.7759/cureus.27093
1929:. 13 February 2020.
1822:appetite-stimulating
1750:studies using human
1663:), a Swiss company.
1604:mast cell stabilizer
1508:mast cell stabilizer
1407:mast cell stabilizer
887:; it also acts as a
802:mast cell stabilizer
63:ketotifen fumarate (
14947:Appetite stimulants
14932:Tricyclic compounds
13704:Dibenzocycloheptene
12719:dihydroergocryptine
11403:MDA (tenamfetamine)
10787:MDA (tenamfetamine)
10752:dihydroergocryptine
9944:MDA (tenamfetamine)
6707:Dexchlorpheniramine
6520:2-Pyridylethylamine
6081:Dexchlorpheniramine
5467:. 25 January 2023.
5441:. 30 January 2023.
5415:. 25 January 2023.
4411:Clinical Immunology
3831:10.2147/JIR.S402900
3423:(6278): 1755–1756.
2903:10.2147/JPR.S195909
2766:. 4 December 2019.
2026:. 13 October 2020.
1996:. 22 October 2009.
1964:. 22 October 2009.
1862:citrus aurantifolia
1671:Society and culture
1645:blood–brain barrier
1547:10-hydroxyketotifen
1543:10-hydroxyketotifen
1461:blood–brain barrier
1459:that can cross the
1457:lipophilic compound
1445:= 38.9 nM for
1321:hypoglycemic agents
1264:acute renal failure
1219:(poor speech), and
861:histamine receptors
822:systemic conditions
253:(Prescription only)
32:
13544:naphthylpiperazine
13315:2-Br-LSD (BOL-148)
13102:naphthylpiperazine
13080:2-Br-LSD (BOL-148)
12682:naphthylpiperazine
12589:2-Br-LSD (BOL-148)
12374:naphthylpiperazine
11250:α-Alkyltryptamines
9764:α-Alkyltryptamines
8048:Serotonin receptor
6772:Homochlorcyclizine
6702:Dexbrompheniramine
6491:Histamine receptor
6071:Dexbrompheniramine
5129:accessdata.fda.gov
5099:accessdata.fda.gov
4386:(Suppl 1): 37–44.
4102:10.1007/BF02259609
4056:10.3390/jcm8091338
3863:Nelson WL (2008).
3783:10.1254/jjp.73.291
3467:"ACE inhibitors".
2639:10.1007/BF03259336
2449:(Suppl 1): S1–S5.
1681:
1592:
1428:= 204 nM for
1167:, antihistamines,
1128:. Less common are
948:seasonal allergies
826:mast cell diseases
818:seasonal allergies
596:as fumarate:
568:as fumarate:
540:as fumarate:
512:as fumarate:
484:as fumarate:
456:as fumarate:
408:as fumarate:
375:as fumarate:
28:
14867:
14866:
13796:Amitriptylinoxide
13714:Dibenzothiazepine
13639:
13638:
13632:
13623:
13614:
13601:
13592:
13583:
13574:
13557:
13556:
13553:
13552:
13523:Unknown/unsorted:
13331:dihydroergotamine
13111:
13110:
13073:Unknown/unsorted:
12723:dihydroergotamine
12691:
12690:
12661:Unknown/unsorted:
12561:
12560:
12383:
12382:
12362:Unknown/unsorted:
12031:ethanol (alcohol)
11981:
11980:
11977:
11976:
11952:Unknown/unsorted:
11343:dihydroergotamine
11170:
11169:
11154:Unknown/unsorted:
10756:dihydroergotamine
10653:
10652:
10640:dihydroergotamine
10633:Unknown/unsorted:
10462:hydroxynefazodone
9619:
9618:
9615:
9614:
9493:
9492:
9470:Unknown/unsorted:
9382:
9381:
9353:Unknown/unsorted:
9119:dihydroergotamine
9068:
9067:
9044:Unknown/unsorted:
8836:dihydroergotamine
8769:
8768:
8743:Unknown/unsorted:
8571:iodocyanopindolol
8259:dihydroergotamine
8112:hydroxynefazodone
8014:
8013:
7984:
7983:
7912:α-Methylhistamine
7907:4-Methylhistamine
7883:
7882:
7706:α-Methylhistamine
7682:
7681:
7451:
7450:
7400:Unknown/unsorted:
7258:hydroxynefazodone
6564:First-generation:
6457:
6456:
6370:Phenylpiperazines
5789:10.3390/v13040558
5609:(12): 1893–1897.
5383:10.1002/ddr.21865
4988:. 12 April 2024.
4955:978-3-527-60749-5
4914:978-0-323-37579-5
4864:(17): 1949–1950.
4721:10.1002/alr.22461
4621:Neurotherapeutics
4428:978-0-323-04404-2
4263:Pharm Dev Technol
4247:978-1-4614-9193-4
4016:10.1111/exd.14602
3985:978-3-642-75561-3
3956:978-81-312-3259-0
3878:978-0-7817-6879-5
3220:Nurse Prescribing
2957:978-3-7643-8530-9
2295:(10): 1427–1443.
2065:. 11 March 2022.
1890:COVID-19 pandemic
1775:anti-inflammatory
1621:benzocycloheptene
1575:benzocycloheptene
1268:urinary retention
1097:urinary retention
1067:Contraindications
971:chronic urticaria
967:atopic dermatitis
959:allergic rhinitis
842:atopic dermatitis
800:medication and a
791:
790:
720:Interactive image
610:CompTox Dashboard
261:
248:
236:
154:
121:
71:
14964:
14937:Anticholinergics
14884:
14883:
14882:
14875:
14690:Anticholinergics
14572:Thiethylperazine
14537:Prochlorperazine
13768:
13709:Dibenzodiazepine
13666:
13659:
13652:
13643:
13642:
13626:
13617:
13611:releasing agents
13604:
13595:
13586:
13577:
13565:
13190:Serotonin (5-HT)
13125:
13124:
12758:Serotonin (5-HT)
12705:
12704:
12603:Serotonin (5-HT)
12575:
12574:
12482:Serotonin (5-HT)
12397:
12396:
12233:Hydroxybupropion
12074:Serotonin (5-HT)
12035:trichloroethanol
12013:
12012:
12001:
12000:
11506:Serotonin (5-HT)
11184:
11183:
10825:Serotonin (5-HT)
10707:levofenfluramine
10691:chlorphentermine
10677:4-Methylaminorex
10667:
10666:
10580:prochlorperazine
10404:Phenoxybenzamine
10374:MIN-117 (WF-516)
10029:Serotonin (5-HT)
9645:
9644:
9633:
9632:
9558:Serotonin (5-HT)
9507:
9506:
9421:Serotonin (5-HT)
9396:
9395:
9167:Serotonin (5-HT)
9082:
9081:
8868:Serotonin (5-HT)
8783:
8782:
8665:MIN-117 (WF-516)
8434:Serotonin (5-HT)
8079:
8078:
8067:
8066:
8041:
8034:
8027:
8018:
8017:
7924:
7897:
7896:
7738:
7696:
7695:
7507:
7465:
7464:
7384:prochlorperazine
7251:Phenylpiperazine
6867:Phenyltoloxamine
6727:Diphenylpyraline
6647:Chlorphenoxamine
6542:
6510:
6509:
6484:
6477:
6470:
6461:
6460:
6414:Chlorphenoxamine
6141:Ethylenediamines
6116:Phenyltoloxamine
6075:+pseudoephedrine
5958:Diphenylpyraline
5938:Chlorphenoxamine
5875:
5873:
5847:
5840:
5833:
5824:
5823:
5812:
5811:
5801:
5791:
5767:
5761:
5760:
5758:
5756:
5750:
5720:(9): 1213–1221.
5711:
5702:
5696:
5695:
5685:
5674:10.5056/jnm15137
5653:
5647:
5646:
5644:
5642:
5615:10.1002/ptr.3227
5594:
5585:
5584:
5574:
5542:
5533:
5532:
5530:
5528:
5513:
5507:
5506:
5504:
5502:
5487:
5481:
5480:
5478:
5476:
5461:
5455:
5454:
5452:
5450:
5435:
5429:
5428:
5426:
5424:
5409:
5403:
5402:
5366:
5360:
5358:
5356:Hanks v. Hubbard
5352:
5346:
5345:
5343:
5341:
5326:
5320:
5319:
5317:
5315:
5300:
5294:
5293:
5291:
5289:
5274:
5268:
5267:
5265:
5263:
5241:
5235:
5234:
5232:
5230:
5211:
5205:
5204:
5202:
5200:
5181:
5175:
5174:
5172:
5170:
5151:
5145:
5144:
5142:
5140:
5121:
5115:
5114:
5112:
5110:
5091:
5085:
5084:
5082:
5080:
5046:
5038:
5032:
5031:
5029:
5027:
5008:
5002:
5001:
4999:
4997:
4978:
4972:
4971:
4969:
4967:
4937:
4931:
4930:
4928:
4926:
4888:
4882:
4881:
4853:
4844:
4843:
4806:
4797:
4796:
4760:
4741:
4740:
4704:
4698:
4697:
4661:
4655:
4654:
4644:
4612:
4606:
4605:
4586:10.1002/etc.4395
4580:(5): 1012–1022.
4569:
4563:
4562:
4552:
4542:
4518:
4512:
4511:
4483:
4477:
4476:
4474:
4472:
4466:
4459:
4451:
4445:
4444:
4442:
4440:
4407:"Antihistamines"
4402:
4396:
4395:
4375:
4369:
4368:
4366:
4342:
4336:
4335:
4325:
4301:
4295:
4294:
4258:
4252:
4251:
4225:
4219:
4218:
4208:
4198:
4174:
4165:
4164:
4154:
4144:
4120:
4114:
4113:
4085:
4079:
4078:
4068:
4058:
4034:
4028:
4027:
3999:
3990:
3989:
3967:
3961:
3960:
3943:"Antihistamines"
3938:
3932:
3931:
3921:
3889:
3883:
3882:
3860:
3854:
3853:
3843:
3833:
3809:
3796:
3795:
3785:
3761:
3752:
3751:
3749:
3747:
3732:
3726:
3725:
3723:
3721:
3706:
3700:
3699:
3679:
3673:
3672:
3644:
3633:
3632:
3630:
3628:
3622:
3615:
3607:
3598:
3597:
3595:
3593:
3587:
3580:
3572:
3563:
3562:
3547:Reactions Weekly
3542:
3536:
3535:
3529:
3527:
3487:
3481:
3480:
3471:(422): 5. 1992.
3469:Reactions Weekly
3464:
3451:
3450:
3440:
3408:
3395:
3394:
3358:
3347:
3346:
3344:
3342:
3323:
3312:
3311:
3309:
3307:
3294:
3272:
3263:
3262:
3242:
3236:
3235:
3215:
3209:
3208:
3206:
3204:
3189:
3183:
3182:
3180:
3178:
3163:
3152:
3151:
3149:
3125:
3119:
3118:
3108:
3084:
3078:
3077:
3057:
3048:
3047:
3037:
3027:
3003:
2997:
2996:
2968:
2962:
2961:
2935:
2929:
2928:
2915:
2905:
2881:
2872:
2871:
2835:
2829:
2828:
2818:
2786:
2780:
2779:
2777:
2775:
2760:
2754:
2753:
2751:
2749:
2743:
2737:. 14 June 2018.
2732:
2724:
2718:
2717:
2715:
2713:
2698:
2687:
2686:
2684:
2682:
2676:
2669:
2661:
2655:
2654:
2652:
2650:
2618:
2612:
2611:
2579:
2573:
2572:
2536:
2530:
2529:
2519:
2509:
2485:
2479:
2478:
2468:
2458:
2434:
2423:
2422:
2420:
2396:
2390:
2389:
2379:
2347:
2336:
2335:
2327:
2321:
2320:
2284:
2273:
2272:
2262:
2252:
2237:Int J Ophthalmol
2228:
2219:
2218:
2182:
2176:
2175:
2165:
2155:
2131:
2125:
2124:
2088:
2071:
2070:
2055:
2040:
2039:
2037:
2035:
2016:
2010:
2009:
2007:
2005:
1984:
1978:
1977:
1975:
1973:
1952:
1943:
1942:
1940:
1938:
1919:
1694:
1693:
1633:chlorpheniramine
1596:noncompetitive H
1523:plasma half-life
1439:antiserotonergic
1436:
1432:
1304:febrile seizures
1288:thrombocytopenia
1077:acute porphyrias
787:
786:
722:
702:
690:
687:
684:
678:
672:
655:
644:
633:
632:
618:
616:
601:
593:
573:
565:
545:
537:
517:
509:
489:
481:
461:
453:
433:
413:
405:
395:
394:
380:
372:
322:
269:
259:
256:
246:
243:
235:
232:
210:
200:
152:
149:
131:
120:
117:
104:
90:
70:
67:
40:
33:
31:
27:
14972:
14971:
14967:
14966:
14965:
14963:
14962:
14961:
14892:
14891:
14890:
14880:
14878:
14870:
14868:
14863:
14754:Cyclobenzaprine
14707:
14684:
14650:Eslicarbazepine
14632:Anticonvulsants
14626:
14607:Triflupromazine
14602:Trifluoperazine
14467:Octomethothepin
14312:Chlorprothixene
14253:
14174:Isopromethazine
14105:
14016:Norbutriptyline
13766:
13761:
13759:Antidepressants
13753:
13724:Dibenzoxazepine
13675:
13670:
13640:
13635:
13549:
13514:
13492:chlorprothixene
13226:
13120:
13107:
13064:
12830:
12700:
12687:
12622:
12570:
12557:
12506:
12392:
12379:
12353:
12321:Volatiles/gases
12133:
12123:trichloroethane
12107:Volatiles/gases
12046:Phenylbiguanide
12008:
11997:
11990:
11973:
11943:
11576:
11446:Phenethylamines
11179:
11166:
11145:
10883:
10711:norfenfluramine
10699:dexfenfluramine
10662:
10649:
10624:
10604:trifluoperazine
10255:Chlorprothixene
10089:
9997:Phenethylamines
9808:Bromo-DragonFLY
9640:
9628:
9611:
9590:
9502:
9489:
9461:
9445:
9391:
9378:
9344:
9248:
9077:
9064:
9035:
8930:
8778:
8765:
8734:
8520:
8104:Antidepressants
8074:
8062:
8053:
8045:
8015:
8010:
7980:
7939:
7922:
7892:
7879:
7753:
7736:
7691:
7678:
7517:
7505:
7460:
7447:
7254:antidepressants
6787:Isopromethazine
6722:Diphenhydramine
6607:Brompheniramine
6552:
6540:
6505:
6496:
6488:
6458:
6453:
6429:Diphenhydramine
6388:
6374:Antidepressants
6358:
6306:Antidepressants
6208:Antidepressants
6188:
6135:
6061:Brompheniramine
5948:Diphenhydramine
5911:
5869:
5861:
5851:
5821:
5816:
5815:
5768:
5764:
5754:
5752:
5748:
5709:
5703:
5699:
5654:
5650:
5640:
5638:
5595:
5588:
5543:
5536:
5526:
5524:
5515:
5514:
5510:
5500:
5498:
5489:
5488:
5484:
5474:
5472:
5463:
5462:
5458:
5448:
5446:
5437:
5436:
5432:
5422:
5420:
5411:
5410:
5406:
5367:
5363:
5354:
5353:
5349:
5339:
5337:
5328:
5327:
5323:
5313:
5311:
5302:
5301:
5297:
5287:
5285:
5276:
5275:
5271:
5261:
5259:
5242:
5238:
5228:
5226:
5213:
5212:
5208:
5198:
5196:
5183:
5182:
5178:
5168:
5166:
5153:
5152:
5148:
5138:
5136:
5123:
5122:
5118:
5108:
5106:
5093:
5092:
5088:
5078:
5076:
5039:
5035:
5025:
5023:
5010:
5009:
5005:
4995:
4993:
4980:
4979:
4975:
4965:
4963:
4956:
4938:
4934:
4924:
4922:
4915:
4889:
4885:
4854:
4847:
4807:
4800:
4761:
4744:
4705:
4701:
4662:
4658:
4613:
4609:
4570:
4566:
4519:
4515:
4484:
4480:
4470:
4468:
4464:
4457:
4453:
4452:
4448:
4438:
4436:
4429:
4403:
4399:
4376:
4372:
4343:
4339:
4302:
4298:
4259:
4255:
4248:
4226:
4222:
4175:
4168:
4129:Front Pharmacol
4121:
4117:
4086:
4082:
4035:
4031:
4010:(7): 993–1004.
4000:
3993:
3986:
3968:
3964:
3957:
3939:
3935:
3890:
3886:
3879:
3861:
3857:
3810:
3799:
3762:
3755:
3745:
3743:
3734:
3733:
3729:
3719:
3717:
3708:
3707:
3703:
3680:
3676:
3645:
3636:
3626:
3624:
3620:
3613:
3609:
3608:
3601:
3591:
3589:
3585:
3578:
3574:
3573:
3566:
3544:
3543:
3539:
3533:encephalopathy.
3525:
3523:
3488:
3484:
3466:
3465:
3454:
3409:
3398:
3359:
3350:
3340:
3338:
3325:
3324:
3315:
3305:
3303:
3292:
3274:
3273:
3266:
3259:10.1002/psb.758
3243:
3239:
3216:
3212:
3202:
3200:
3191:
3190:
3186:
3176:
3174:
3165:
3164:
3155:
3126:
3122:
3085:
3081:
3058:
3051:
3004:
3000:
2969:
2965:
2958:
2936:
2932:
2882:
2875:
2836:
2832:
2801:(1): CD001384.
2787:
2783:
2773:
2771:
2762:
2761:
2757:
2747:
2745:
2741:
2730:
2726:
2725:
2721:
2711:
2709:
2700:
2699:
2690:
2680:
2678:
2674:
2667:
2663:
2662:
2658:
2648:
2646:
2619:
2615:
2580:
2576:
2537:
2533:
2486:
2482:
2435:
2426:
2397:
2393:
2348:
2339:
2328:
2324:
2285:
2276:
2229:
2222:
2193:(11): 1437–52.
2183:
2179:
2132:
2128:
2089:
2074:
2057:
2056:
2043:
2033:
2031:
2018:
2017:
2013:
2003:
2001:
1986:
1985:
1981:
1971:
1969:
1954:
1953:
1946:
1936:
1934:
1921:
1920:
1909:
1904:
1882:
1870:
1796:
1791:
1740:
1735:
1714:
1701:
1695:prescriptions.
1691:
1689:
1686:
1673:
1653:
1637:diphenhydramine
1613:
1599:
1594:Ketotifen is a
1589:
1584:
1580:
1559:
1551:glucuronic acid
1455:Ketotifen is a
1450:
1444:
1434:
1427:
1422:anticholinergic
1404:
1398:
1388:inverse agonist
1379:Ketotifen is a
1377:
1316:
1256:pulmonary edema
1185:
1177:antidepressants
1173:benzodiazepines
1122:
1069:
1034:bronchodilators
1007:calcium channel
909:
860:
782:
780:
775:
772:
767:
762:
757:
756:
745:
742:
737:
736:
725:
700:
681:
675:
636:
612:
604:
576:
548:
520:
492:
464:
436:
416:
391:
383:
355:
352:
343:
342:
320:
297:Protein binding
287:Bioavailability
279:Pharmacokinetic
273:
267:
214:
167:
160:
141:
134:
24:
17:
12:
11:
5:
14970:
14960:
14959:
14954:
14949:
14944:
14942:Antihistamines
14939:
14934:
14929:
14924:
14919:
14914:
14909:
14904:
14889:
14888:
14865:
14864:
14862:
14861:
14856:
14851:
14846:
14841:
14836:
14831:
14826:
14821:
14816:
14811:
14806:
14801:
14796:
14791:
14786:
14781:
14779:Methylene blue
14776:
14771:
14766:
14761:
14756:
14751:
14746:
14741:
14736:
14731:
14726:
14724:Aminopromazine
14721:
14715:
14713:
14709:
14708:
14706:
14705:
14700:
14694:
14692:
14686:
14685:
14683:
14682:
14677:
14672:
14667:
14662:
14657:
14652:
14647:
14642:
14636:
14634:
14628:
14627:
14625:
14624:
14622:Zuclopenthixol
14619:
14614:
14609:
14604:
14599:
14594:
14589:
14584:
14579:
14574:
14569:
14564:
14559:
14554:
14549:
14544:
14539:
14534:
14529:
14524:
14522:Piperacetazine
14519:
14514:
14509:
14504:
14499:
14494:
14489:
14484:
14479:
14474:
14469:
14464:
14459:
14454:
14449:
14444:
14439:
14434:
14429:
14424:
14419:
14414:
14409:
14407:Isofloxythepin
14404:
14399:
14394:
14389:
14384:
14379:
14374:
14369:
14364:
14359:
14354:
14349:
14344:
14339:
14334:
14329:
14324:
14319:
14314:
14309:
14307:Chlorpromazine
14304:
14299:
14294:
14289:
14284:
14279:
14274:
14269:
14267:Acetophenazine
14263:
14261:
14259:Antipsychotics
14255:
14254:
14252:
14251:
14246:
14241:
14236:
14231:
14226:
14221:
14216:
14211:
14206:
14201:
14196:
14191:
14186:
14181:
14176:
14171:
14166:
14161:
14156:
14151:
14146:
14141:
14136:
14134:Cyproheptadine
14131:
14126:
14121:
14115:
14113:
14111:Antihistamines
14107:
14106:
14104:
14103:
14098:
14093:
14088:
14083:
14078:
14073:
14068:
14063:
14058:
14053:
14048:
14043:
14038:
14033:
14028:
14023:
14018:
14013:
14008:
14003:
13998:
13993:
13988:
13983:
13978:
13973:
13968:
13963:
13958:
13953:
13948:
13943:
13938:
13933:
13931:Imipraminoxide
13928:
13923:
13918:
13913:
13908:
13903:
13898:
13893:
13888:
13883:
13878:
13873:
13868:
13863:
13858:
13853:
13851:Cyanodothiepin
13848:
13843:
13838:
13833:
13828:
13823:
13818:
13813:
13808:
13803:
13798:
13793:
13788:
13783:
13778:
13772:
13770:
13755:
13754:
13752:
13751:
13746:
13741:
13736:
13731:
13726:
13721:
13719:Dibenzothiepin
13716:
13711:
13706:
13701:
13696:
13691:
13685:
13683:
13677:
13676:
13669:
13668:
13661:
13654:
13646:
13637:
13636:
13634:
13633:
13624:
13615:
13602:
13593:
13584:
13575:
13562:
13559:
13558:
13555:
13554:
13551:
13550:
13548:
13547:
13537:
13519:
13516:
13515:
13513:
13512:
13507:
13488:chlorpromazine
13484:acetophenazine
13477:
13459:
13437:
13432:
13427:
13422:
13417:
13412:
13407:
13402:
13397:
13392:
13387:
13382:
13377:
13372:
13367:
13362:
13308:
13303:
13298:
13293:
13231:
13228:
13227:
13225:
13224:
13202:
13192:
13187:
13182:
13177:
13172:
13167:
13162:
13152:
13147:
13142:
13137:
13128:
13122:
13118:
13113:
13112:
13109:
13108:
13106:
13105:
13095:
13069:
13066:
13065:
13063:
13062:
13055:chlorpromazine
13048:
13026:
13012:
13007:
13002:
12997:
12992:
12987:
12982:
12977:
12972:
12967:
12962:
12957:
12952:
12947:
12942:
12937:
12932:
12927:
12922:
12917:
12912:
12907:
12902:
12897:
12892:
12887:
12882:
12844:
12835:
12832:
12831:
12829:
12828:
12823:
12818:
12760:
12755:
12750:
12708:
12702:
12698:
12693:
12692:
12689:
12688:
12686:
12685:
12675:
12657:
12656:
12651:
12646:
12641:
12636:
12627:
12624:
12623:
12621:
12620:
12618:Valerenic acid
12615:
12605:
12600:
12578:
12572:
12568:
12563:
12562:
12559:
12558:
12556:
12555:
12550:
12545:
12540:
12535:
12530:
12525:
12520:
12511:
12508:
12507:
12505:
12504:
12499:
12494:
12489:
12484:
12479:
12474:
12469:
12464:
12459:
12454:
12449:
12444:
12442:Metoclopramide
12439:
12434:
12429:
12424:
12419:
12414:
12409:
12400:
12394:
12390:
12385:
12384:
12381:
12380:
12378:
12377:
12367:
12358:
12355:
12354:
12352:
12351:
12346:
12341:
12336:
12318:
12308:
12303:
12298:
12293:
12275:
12270:
12265:
12260:
12255:
12250:
12245:
12240:
12235:
12230:
12225:
12220:
12215:
12210:
12205:
12200:
12195:
12190:
12185:
12180:
12162:
12157:
12152:
12147:
12138:
12135:
12134:
12132:
12131:
12126:
12104:
12086:
12081:
12076:
12071:
12066:
12048:
12043:
12038:
12016:
12010:
12006:
11998:
11992:
11988:
11983:
11982:
11979:
11978:
11975:
11974:
11972:
11971:
11957:
11948:
11945:
11944:
11942:
11941:
11936:
11917:chlorpromazine
11910:
11896:
11891:
11886:
11881:
11851:
11846:
11841:
11836:
11831:
11826:
11821:
11816:
11811:
11806:
11801:
11796:
11791:
11786:
11781:
11776:
11771:
11766:
11761:
11756:
11751:
11746:
11741:
11736:
11731:
11693:
11688:
11683:
11678:
11673:
11671:Cyproheptadine
11668:
11663:
11658:
11653:
11595:
11590:
11581:
11578:
11577:
11575:
11574:
11569:
11564:
11559:
11554:
11508:
11503:
11498:
11493:
11488:
11483:
11457:
11443:
11438:
11433:
11428:
11423:
11418:
11396:
11391:
11386:
11328:
11306:
11301:
11296:
11291:
11286:
11281:
11247:
11221:
11187:
11181:
11177:
11172:
11171:
11168:
11167:
11165:
11164:
11150:
11147:
11146:
11144:
11143:
11138:
11133:
11130:chlorpromazine
11123:
11118:
11100:
11095:
11090:
11085:
11080:
11075:
11070:
11065:
11060:
11055:
11050:
11045:
11040:
11035:
11030:
11025:
11020:
11015:
11010:
11005:
11000:
10995:
10965:
10960:
10958:Cyproheptadine
10955:
10897:
10888:
10885:
10884:
10882:
10881:
10827:
10822:
10817:
10812:
10802:
10780:
10775:
10741:
10719:
10714:
10684:
10679:
10670:
10664:
10660:
10655:
10654:
10651:
10650:
10648:
10647:
10629:
10626:
10625:
10623:
10622:
10617:
10612:
10607:
10552:chlorpromazine
10545:
10535:
10505:
10500:
10495:
10490:
10485:
10451:
10446:
10441:
10436:
10431:
10426:
10421:
10416:
10411:
10406:
10401:
10396:
10391:
10386:
10381:
10376:
10371:
10366:
10361:
10356:
10351:
10346:
10341:
10336:
10331:
10326:
10321:
10316:
10282:
10277:
10272:
10267:
10262:
10257:
10252:
10150:
10145:
10130:cyproheptadine
10126:Antihistamines
10123:
10118:
10113:
10108:
10103:
10094:
10091:
10090:
10088:
10087:
10041:
10036:
10031:
10026:
10008:
9994:
9992:SCHEMBL5334361
9989:
9984:
9979:
9974:
9969:
9964:
9959:
9937:
9932:
9927:
9922:
9917:
9847:
9842:
9820:
9815:
9810:
9805:
9800:
9795:
9761:
9735:
9730:
9725:
9695:
9648:
9642:
9638:
9630:
9626:
9621:
9620:
9617:
9616:
9613:
9612:
9610:
9609:
9604:
9595:
9592:
9591:
9589:
9588:
9578:
9560:
9555:
9550:
9545:
9524:
9519:
9510:
9504:
9500:
9495:
9494:
9491:
9490:
9488:
9487:
9466:
9463:
9462:
9460:
9459:
9450:
9447:
9446:
9444:
9443:
9433:
9423:
9418:
9408:
9399:
9393:
9389:
9384:
9383:
9380:
9379:
9377:
9376:
9358:
9349:
9346:
9345:
9343:
9342:
9337:
9332:
9327:
9322:
9317:
9312:
9307:
9302:
9297:
9292:
9287:
9282:
9272:
9267:
9262:
9253:
9250:
9249:
9247:
9246:
9216:
9174:
9169:
9164:
9159:
9154:
9149:
9144:
9139:
9134:
9104:
9099:
9094:
9085:
9079:
9075:
9070:
9069:
9066:
9065:
9063:
9062:
9040:
9037:
9036:
9034:
9033:
9028:
9023:
9018:
9013:
9008:
9003:
8998:
8993:
8983:
8978:
8944:
8935:
8932:
8931:
8929:
8928:
8923:
8901:
8896:
8870:
8865:
8860:
8855:
8825:
8820:
8815:
8810:
8805:
8800:
8795:
8786:
8780:
8776:
8771:
8770:
8767:
8766:
8764:
8763:
8753:
8748:
8739:
8736:
8735:
8733:
8732:
8727:
8722:
8717:
8712:
8707:
8702:
8697:
8692:
8687:
8682:
8677:
8672:
8667:
8662:
8657:
8652:
8647:
8642:
8637:
8632:
8627:
8617:
8612:
8607:
8602:
8552:
8547:
8525:
8522:
8521:
8519:
8518:
8513:
8508:
8503:
8498:
8493:
8488:
8446:
8441:
8436:
8431:
8426:
8421:
8416:
8411:
8406:
8401:
8396:
8391:
8386:
8381:
8376:
8371:
8366:
8361:
8356:
8351:
8346:
8341:
8336:
8331:
8326:
8321:
8316:
8311:
8306:
8301:
8296:
8291:
8286:
8244:
8239:
8234:
8229:
8224:
8219:
8214:
8209:
8204:
8199:
8173:
8135:
8101:
8096:
8091:
8082:
8076:
8072:
8064:
8060:
8055:
8054:
8044:
8043:
8036:
8029:
8021:
8012:
8011:
8009:
8008:
8003:
7998:
7993:
7989:
7986:
7985:
7982:
7981:
7979:
7978:
7973:
7968:
7963:
7958:
7953:
7947:
7945:
7941:
7940:
7938:
7937:
7932:
7927:
7919:
7914:
7909:
7903:
7901:
7894:
7890:
7885:
7884:
7881:
7880:
7878:
7877:
7872:
7867:
7862:
7857:
7852:
7847:
7842:
7837:
7835:Iodophenpropit
7832:
7827:
7822:
7817:
7812:
7807:
7802:
7797:
7792:
7787:
7782:
7777:
7772:
7767:
7761:
7759:
7755:
7754:
7752:
7751:
7746:
7741:
7733:
7728:
7723:
7718:
7713:
7708:
7702:
7700:
7693:
7689:
7684:
7683:
7680:
7679:
7677:
7676:
7671:
7666:
7661:
7656:
7651:
7646:
7641:
7636:
7631:
7626:
7621:
7616:
7611:
7606:
7601:
7596:
7591:
7586:
7581:
7576:
7571:
7566:
7561:
7556:
7551:
7546:
7541:
7536:
7531:
7525:
7523:
7519:
7518:
7516:
7515:
7510:
7502:
7497:
7492:
7487:
7482:
7477:
7471:
7469:
7462:
7458:
7453:
7452:
7449:
7448:
7446:
7445:
7440:
7435:
7430:
7425:
7420:
7415:
7410:
7405:
7396:
7395:
7364:chlorpromazine
7357:
7303:
7273:
7248:
7190:
7189:
7184:
7179:
7174:
7169:
7164:
7159:
7154:
7149:
7144:
7139:
7134:
7129:
7124:
7119:
7114:
7109:
7104:
7099:
7094:
7089:
7084:
7079:
7077:Levocetirizine
7074:
7069:
7064:
7059:
7054:
7049:
7044:
7039:
7034:
7029:
7024:
7019:
7017:Clobenztropine
7014:
7009:
7004:
6999:
6994:
6989:
6984:
6979:
6974:
6969:
6964:
6959:
6954:
6949:
6940:
6939:
6934:
6932:Tripelennamine
6929:
6924:
6919:
6914:
6909:
6904:
6899:
6894:
6889:
6884:
6879:
6874:
6869:
6864:
6859:
6854:
6849:
6844:
6839:
6834:
6829:
6824:
6819:
6814:
6809:
6804:
6799:
6794:
6789:
6784:
6779:
6774:
6769:
6767:Histapyrrodine
6764:
6759:
6754:
6749:
6744:
6739:
6734:
6729:
6724:
6719:
6714:
6712:Dimenhydrinate
6709:
6704:
6699:
6694:
6689:
6684:
6682:Cyproheptadine
6679:
6674:
6669:
6664:
6659:
6654:
6649:
6644:
6642:Chlorphenamine
6639:
6634:
6632:Chloropyramine
6629:
6627:Chlorcyclizine
6624:
6619:
6614:
6609:
6604:
6599:
6594:
6589:
6584:
6579:
6574:
6569:
6560:
6558:
6554:
6553:
6551:
6550:
6545:
6537:
6532:
6527:
6522:
6516:
6514:
6507:
6503:
6498:
6497:
6487:
6486:
6479:
6472:
6464:
6455:
6454:
6452:
6451:
6446:
6441:
6436:
6431:
6426:
6421:
6416:
6411:
6409:Chloropyramine
6406:
6400:
6398:
6390:
6389:
6387:
6386:
6381:
6366:
6364:
6360:
6359:
6357:
6356:
6351:
6346:
6341:
6336:
6331:
6326:
6321:
6299:
6298:
6293:
6288:
6283:
6278:
6273:
6268:
6263:
6256:Phenothiazines
6251:
6250:
6245:
6240:
6235:
6230:
6225:
6223:Cyproheptadine
6220:
6215:
6198:
6196:
6190:
6189:
6187:
6186:
6181:
6176:
6171:
6166:
6161:
6159:Histapyrrodine
6156:
6154:Chloropyramine
6151:
6145:
6143:
6137:
6136:
6134:
6133:
6128:
6123:
6118:
6113:
6108:
6103:
6094:
6093:
6088:
6085:+betamethasone
6078:
6068:
6066:Chlorphenamine
6063:
6054:
6053:
6048:
6043:
6038:
6033:
6028:
6023:
6021:Chlorcyclizine
6018:
6017:
6016:
6014:Levocetirizine
6006:
5994:
5993:
5988:
5976:
5975:
5970:
5965:
5960:
5955:
5945:
5940:
5935:
5930:
5921:
5919:
5917:Diarylmethanes
5913:
5912:
5910:
5909:
5904:
5899:
5894:
5889:
5884:
5878:
5876:
5867:Benzimidazoles
5863:
5862:
5854:Antihistamines
5850:
5849:
5842:
5835:
5827:
5820:
5819:External links
5817:
5814:
5813:
5762:
5697:
5668:(2): 181–192.
5648:
5586:
5534:
5508:
5482:
5456:
5430:
5404:
5377:(2): 362–367.
5361:
5347:
5321:
5295:
5269:
5236:
5206:
5176:
5146:
5116:
5086:
5033:
5003:
4973:
4954:
4932:
4913:
4883:
4845:
4798:
4742:
4715:(2): 265–270.
4699:
4672:(5): 480–485.
4656:
4627:(1): 218–234.
4607:
4564:
4513:
4494:(3): 283–293.
4478:
4446:
4427:
4397:
4370:
4337:
4296:
4253:
4246:
4220:
4183:BMC Ophthalmol
4166:
4115:
4080:
4029:
3991:
3984:
3962:
3955:
3933:
3904:(9): 836–842.
3884:
3877:
3855:
3797:
3776:(4): 291–298.
3753:
3727:
3701:
3690:(5): 503–515.
3674:
3634:
3599:
3564:
3537:
3482:
3452:
3396:
3369:(5): 387–392.
3348:
3331:www.mims.co.uk
3313:
3264:
3237:
3226:(4): 166–170.
3210:
3184:
3153:
3140:(6): 203–207.
3120:
3079:
3068:(4): 197–201.
3049:
2998:
2979:(9): 607–615.
2963:
2956:
2930:
2873:
2846:(4): 255–262.
2830:
2781:
2755:
2719:
2688:
2656:
2633:(5): 400–411.
2613:
2574:
2547:(3): 353–365.
2531:
2480:
2424:
2391:
2362:(6): 433–436.
2337:
2322:
2274:
2243:(2): 286–292.
2220:
2177:
2126:
2099:(3): 412–448.
2072:
2041:
2011:
1979:
1944:
1906:
1905:
1903:
1900:
1881:
1878:
1869:
1866:
1842:adipose tissue
1795:
1792:
1790:
1787:
1739:
1736:
1734:
1731:
1713:
1710:
1700:
1697:
1685:
1682:
1672:
1669:
1652:
1649:
1629:cyproheptadine
1611:
1600:-antihistamine
1597:
1587:
1582:
1578:
1558:
1557:Classification
1555:
1521:Ketotifen has
1516:chronic asthma
1481:prostaglandins
1448:
1442:
1425:
1402:
1396:
1386:– that is, an
1376:
1373:
1315:
1312:
1248:cardiac arrest
1240:blurred vision
1221:slurred speech
1197:hallucinations
1184:
1181:
1121:
1118:
1068:
1065:
1063:in the body).
944:
943:
932:
908:
905:
877:antihistaminic
858:
850:food allergies
806:conjunctivitis
789:
788:
777:
776:
774:
773:
770:
768:
765:
763:
760:
752:
751:
750:
747:
746:
744:
743:
740:
732:
731:
730:
727:
726:
724:
723:
715:
713:
705:
704:
698:
692:
691:
679:
673:
668:
662:
661:
657:
656:
646:
638:
637:
635:
634:
621:
619:
606:
605:
603:
602:
594:
586:
584:
578:
577:
575:
574:
566:
558:
556:
550:
549:
547:
546:
538:
530:
528:
522:
521:
519:
518:
510:
502:
500:
494:
493:
491:
490:
482:
474:
472:
466:
465:
463:
462:
454:
446:
444:
438:
437:
435:
434:
426:
424:
418:
417:
415:
414:
406:
398:
396:
385:
384:
382:
381:
373:
365:
363:
357:
356:
354:
353:
346:
338:
337:
336:
333:
332:
328:
327:
324:
315:
314:
309:
303:
302:
299:
293:
292:
289:
283:
282:
275:
274:
272:
271:
254:
241:
229:
227:
221:
220:
216:
215:
213:
212:
189:
187:
181:
180:
170:
168:administration
162:
161:
159:
158:
156:
146:
144:
136:
135:
133:
132:
114:
112:
106:
105:
98:
92:
91:
84:
74:
73:
61:
57:
56:
53:
47:
46:
42:
41:
15:
9:
6:
4:
3:
2:
14969:
14958:
14955:
14953:
14950:
14948:
14945:
14943:
14940:
14938:
14935:
14933:
14930:
14928:
14925:
14923:
14920:
14918:
14915:
14913:
14910:
14908:
14905:
14903:
14900:
14899:
14897:
14887:
14877:
14876:
14873:
14860:
14857:
14855:
14852:
14850:
14847:
14845:
14842:
14840:
14837:
14835:
14832:
14830:
14827:
14825:
14822:
14820:
14817:
14815:
14812:
14810:
14807:
14805:
14802:
14800:
14797:
14795:
14792:
14790:
14787:
14785:
14782:
14780:
14777:
14775:
14772:
14770:
14767:
14765:
14762:
14760:
14757:
14755:
14752:
14750:
14747:
14745:
14742:
14740:
14737:
14735:
14732:
14730:
14727:
14725:
14722:
14720:
14717:
14716:
14714:
14710:
14704:
14701:
14699:
14696:
14695:
14693:
14691:
14687:
14681:
14678:
14676:
14675:Oxitriptyline
14673:
14671:
14670:Oxcarbazepine
14668:
14666:
14665:Licarbazepine
14663:
14661:
14658:
14656:
14653:
14651:
14648:
14646:
14643:
14641:
14640:Carbamazepine
14638:
14637:
14635:
14633:
14629:
14623:
14620:
14618:
14615:
14613:
14610:
14608:
14605:
14603:
14600:
14598:
14595:
14593:
14590:
14588:
14585:
14583:
14580:
14578:
14577:Thiopropazate
14575:
14573:
14570:
14568:
14565:
14563:
14562:Sulforidazine
14560:
14558:
14555:
14553:
14550:
14548:
14545:
14543:
14540:
14538:
14535:
14533:
14530:
14528:
14525:
14523:
14520:
14518:
14515:
14513:
14510:
14508:
14505:
14503:
14500:
14498:
14495:
14493:
14492:Peradithiepin
14490:
14488:
14485:
14483:
14480:
14478:
14475:
14473:
14470:
14468:
14465:
14463:
14460:
14458:
14455:
14453:
14450:
14448:
14445:
14443:
14440:
14438:
14435:
14433:
14432:Meperathiepin
14430:
14428:
14425:
14423:
14420:
14418:
14415:
14413:
14410:
14408:
14405:
14403:
14400:
14398:
14395:
14393:
14390:
14388:
14385:
14383:
14380:
14378:
14375:
14373:
14370:
14368:
14365:
14363:
14362:Docloxythepin
14360:
14358:
14355:
14353:
14350:
14348:
14345:
14343:
14340:
14338:
14335:
14333:
14330:
14328:
14325:
14323:
14320:
14318:
14315:
14313:
14310:
14308:
14305:
14303:
14300:
14298:
14295:
14293:
14290:
14288:
14285:
14283:
14280:
14278:
14275:
14273:
14270:
14268:
14265:
14264:
14262:
14260:
14256:
14250:
14247:
14245:
14242:
14240:
14237:
14235:
14232:
14230:
14227:
14225:
14222:
14220:
14217:
14215:
14212:
14210:
14207:
14205:
14202:
14200:
14197:
14195:
14192:
14190:
14187:
14185:
14182:
14180:
14177:
14175:
14172:
14170:
14167:
14165:
14162:
14160:
14157:
14155:
14152:
14150:
14149:Desloratadine
14147:
14145:
14142:
14140:
14137:
14135:
14132:
14130:
14127:
14125:
14122:
14120:
14117:
14116:
14114:
14112:
14108:
14102:
14099:
14097:
14094:
14092:
14089:
14087:
14084:
14082:
14079:
14077:
14074:
14072:
14069:
14067:
14066:Protriptyline
14064:
14062:
14059:
14057:
14054:
14052:
14049:
14047:
14044:
14042:
14039:
14037:
14034:
14032:
14029:
14027:
14024:
14022:
14019:
14017:
14014:
14012:
14011:Nitroxazepine
14009:
14007:
14006:Monometacrine
14004:
14002:
13999:
13997:
13994:
13992:
13989:
13987:
13984:
13982:
13979:
13977:
13974:
13972:
13969:
13967:
13964:
13962:
13959:
13957:
13954:
13952:
13949:
13947:
13944:
13942:
13939:
13937:
13934:
13932:
13929:
13927:
13924:
13922:
13919:
13917:
13914:
13912:
13909:
13907:
13904:
13902:
13899:
13897:
13894:
13892:
13889:
13887:
13884:
13882:
13879:
13877:
13874:
13872:
13869:
13867:
13864:
13862:
13859:
13857:
13856:Demexiptiline
13854:
13852:
13849:
13847:
13844:
13842:
13839:
13837:
13834:
13832:
13829:
13827:
13824:
13822:
13819:
13817:
13814:
13812:
13809:
13807:
13804:
13802:
13799:
13797:
13794:
13792:
13791:Amitriptyline
13789:
13787:
13784:
13782:
13779:
13777:
13774:
13773:
13771:
13765:
13760:
13756:
13750:
13747:
13745:
13742:
13740:
13737:
13735:
13734:Phenothiazine
13732:
13730:
13727:
13725:
13722:
13720:
13717:
13715:
13712:
13710:
13707:
13705:
13702:
13700:
13699:Dibenzazepine
13697:
13695:
13692:
13690:
13687:
13686:
13684:
13682:
13678:
13674:
13667:
13662:
13660:
13655:
13653:
13648:
13647:
13644:
13631:
13630:
13625:
13622:
13621:
13616:
13613:
13612:
13608:
13603:
13600:
13599:
13598:Melatonergics
13594:
13591:
13590:
13589:Dopaminergics
13585:
13582:
13581:
13576:
13573:
13572:
13569:
13564:
13563:
13560:
13545:
13541:
13538:
13535:
13531:
13527:
13524:
13521:
13520:
13517:
13511:
13508:
13505:
13501:
13497:
13493:
13489:
13485:
13481:
13478:
13475:
13471:
13467:
13466:amitriptyline
13463:
13460:
13457:
13453:
13449:
13445:
13441:
13438:
13436:
13433:
13431:
13428:
13426:
13423:
13421:
13418:
13416:
13413:
13411:
13408:
13406:
13403:
13401:
13398:
13396:
13393:
13391:
13388:
13386:
13383:
13381:
13378:
13376:
13373:
13371:
13368:
13366:
13363:
13360:
13356:
13352:
13348:
13344:
13340:
13336:
13332:
13328:
13324:
13323:bromocriptine
13320:
13316:
13312:
13309:
13307:
13304:
13302:
13299:
13297:
13294:
13291:
13287:
13283:
13279:
13275:
13271:
13267:
13263:
13259:
13255:
13254:brexpiprazole
13251:
13247:
13243:
13239:
13236:
13233:
13232:
13229:
13222:
13218:
13214:
13210:
13206:
13203:
13200:
13196:
13193:
13191:
13188:
13186:
13183:
13181:
13178:
13176:
13173:
13171:
13168:
13166:
13163:
13160:
13156:
13153:
13151:
13148:
13146:
13143:
13141:
13138:
13136:
13133:
13130:
13129:
13126:
13123:
13121:
13114:
13103:
13099:
13096:
13093:
13089:
13085:
13084:bromocriptine
13081:
13077:
13074:
13071:
13070:
13067:
13060:
13056:
13052:
13049:
13046:
13045:nortriptyline
13042:
13038:
13034:
13033:amitriptyline
13030:
13027:
13024:
13020:
13016:
13013:
13011:
13008:
13006:
13003:
13001:
12998:
12996:
12993:
12991:
12988:
12986:
12983:
12981:
12978:
12976:
12973:
12971:
12968:
12966:
12963:
12961:
12958:
12956:
12953:
12951:
12948:
12946:
12943:
12941:
12938:
12936:
12933:
12931:
12928:
12926:
12923:
12921:
12918:
12916:
12913:
12911:
12908:
12906:
12903:
12901:
12898:
12896:
12893:
12891:
12888:
12886:
12883:
12880:
12876:
12872:
12868:
12864:
12860:
12856:
12852:
12848:
12845:
12843:
12840:
12837:
12836:
12833:
12827:
12824:
12822:
12819:
12816:
12812:
12808:
12804:
12800:
12796:
12792:
12788:
12784:
12780:
12776:
12772:
12768:
12764:
12761:
12759:
12756:
12754:
12751:
12748:
12744:
12740:
12736:
12732:
12728:
12724:
12720:
12716:
12713:
12710:
12709:
12706:
12703:
12701:
12694:
12683:
12679:
12676:
12673:
12669:
12665:
12662:
12659:
12658:
12655:
12652:
12650:
12647:
12645:
12642:
12640:
12637:
12635:
12632:
12629:
12628:
12625:
12619:
12616:
12613:
12609:
12606:
12604:
12601:
12598:
12594:
12590:
12586:
12583:
12580:
12579:
12576:
12573:
12571:
12564:
12554:
12551:
12549:
12546:
12544:
12541:
12539:
12536:
12534:
12531:
12529:
12526:
12524:
12521:
12519:
12516:
12513:
12512:
12509:
12503:
12500:
12498:
12495:
12493:
12490:
12488:
12485:
12483:
12480:
12478:
12475:
12473:
12470:
12468:
12465:
12463:
12460:
12458:
12455:
12453:
12450:
12448:
12445:
12443:
12440:
12438:
12435:
12433:
12430:
12428:
12425:
12423:
12420:
12418:
12415:
12413:
12410:
12408:
12405:
12402:
12401:
12398:
12395:
12393:
12386:
12375:
12371:
12368:
12366:
12363:
12360:
12359:
12356:
12350:
12347:
12345:
12342:
12340:
12337:
12334:
12330:
12326:
12325:nitrous oxide
12322:
12319:
12316:
12312:
12309:
12307:
12304:
12302:
12299:
12297:
12294:
12291:
12287:
12283:
12279:
12276:
12274:
12273:Tedatioxetine
12271:
12269:
12266:
12264:
12261:
12259:
12256:
12254:
12251:
12249:
12246:
12244:
12241:
12239:
12236:
12234:
12231:
12229:
12226:
12224:
12223:Galanolactone
12221:
12219:
12216:
12214:
12211:
12209:
12206:
12204:
12201:
12199:
12196:
12194:
12191:
12189:
12186:
12184:
12181:
12178:
12174:
12170:
12166:
12163:
12161:
12158:
12156:
12153:
12151:
12148:
12146:
12143:
12140:
12139:
12136:
12130:
12127:
12124:
12120:
12116:
12112:
12108:
12105:
12102:
12098:
12094:
12090:
12087:
12085:
12082:
12080:
12077:
12075:
12072:
12070:
12067:
12064:
12060:
12056:
12052:
12049:
12047:
12044:
12042:
12039:
12036:
12032:
12028:
12024:
12021:
12018:
12017:
12014:
12011:
12009:
12002:
11999:
11996:
11991:
11984:
11969:
11965:
11961:
11958:
11956:
11953:
11950:
11949:
11946:
11940:
11937:
11934:
11930:
11926:
11922:
11918:
11914:
11911:
11908:
11907:nortriptyline
11904:
11903:amitriptyline
11900:
11897:
11895:
11892:
11890:
11887:
11885:
11882:
11879:
11875:
11871:
11867:
11866:esmirtazapine
11863:
11859:
11855:
11852:
11850:
11849:Tedatioxetine
11847:
11845:
11842:
11840:
11837:
11835:
11832:
11830:
11827:
11825:
11822:
11820:
11817:
11815:
11812:
11810:
11807:
11805:
11802:
11800:
11797:
11795:
11792:
11790:
11787:
11785:
11782:
11780:
11777:
11775:
11772:
11770:
11767:
11765:
11762:
11760:
11757:
11755:
11752:
11750:
11747:
11745:
11742:
11740:
11737:
11735:
11732:
11729:
11725:
11721:
11717:
11713:
11709:
11705:
11704:bromocriptine
11701:
11697:
11694:
11692:
11689:
11687:
11684:
11682:
11681:Desmetramadol
11679:
11677:
11674:
11672:
11669:
11667:
11664:
11662:
11659:
11657:
11654:
11651:
11647:
11643:
11639:
11635:
11631:
11627:
11623:
11619:
11615:
11611:
11607:
11603:
11599:
11596:
11594:
11591:
11589:
11586:
11583:
11582:
11579:
11573:
11570:
11568:
11565:
11563:
11560:
11558:
11555:
11552:
11548:
11544:
11540:
11536:
11532:
11528:
11524:
11520:
11516:
11512:
11509:
11507:
11504:
11502:
11499:
11497:
11494:
11492:
11489:
11487:
11484:
11481:
11477:
11473:
11469:
11465:
11461:
11458:
11455:
11451:
11447:
11444:
11442:
11439:
11437:
11434:
11432:
11429:
11427:
11424:
11422:
11419:
11416:
11412:
11408:
11404:
11400:
11397:
11395:
11392:
11390:
11387:
11384:
11380:
11376:
11372:
11368:
11364:
11360:
11356:
11352:
11348:
11344:
11340:
11336:
11332:
11329:
11326:
11322:
11318:
11314:
11310:
11307:
11305:
11302:
11300:
11297:
11295:
11292:
11290:
11287:
11285:
11282:
11279:
11275:
11271:
11267:
11263:
11259:
11255:
11251:
11248:
11245:
11241:
11237:
11233:
11229:
11225:
11222:
11219:
11215:
11211:
11207:
11203:
11199:
11195:
11192:
11189:
11188:
11185:
11182:
11180:
11173:
11162:
11158:
11155:
11152:
11151:
11148:
11142:
11139:
11137:
11134:
11131:
11127:
11124:
11122:
11119:
11116:
11112:
11108:
11104:
11101:
11099:
11096:
11094:
11091:
11089:
11086:
11084:
11081:
11079:
11076:
11074:
11071:
11069:
11066:
11064:
11061:
11059:
11056:
11054:
11051:
11049:
11046:
11044:
11041:
11039:
11036:
11034:
11031:
11029:
11026:
11024:
11021:
11019:
11016:
11014:
11011:
11009:
11006:
11004:
11001:
10999:
10996:
10993:
10989:
10985:
10981:
10977:
10976:bromocriptine
10973:
10969:
10966:
10964:
10961:
10959:
10956:
10953:
10949:
10945:
10941:
10937:
10933:
10929:
10925:
10921:
10917:
10916:brexpiprazole
10913:
10909:
10905:
10901:
10898:
10896:
10893:
10890:
10889:
10886:
10879:
10875:
10871:
10867:
10863:
10859:
10855:
10851:
10847:
10843:
10839:
10835:
10831:
10828:
10826:
10823:
10821:
10818:
10816:
10813:
10810:
10806:
10803:
10800:
10796:
10792:
10788:
10784:
10781:
10779:
10776:
10773:
10769:
10765:
10761:
10757:
10753:
10749:
10745:
10742:
10739:
10735:
10731:
10727:
10723:
10720:
10718:
10715:
10712:
10708:
10704:
10700:
10696:
10692:
10688:
10685:
10683:
10680:
10678:
10675:
10672:
10671:
10668:
10665:
10663:
10656:
10645:
10641:
10637:
10634:
10631:
10630:
10627:
10621:
10618:
10616:
10613:
10611:
10608:
10605:
10601:
10597:
10593:
10589:
10585:
10581:
10577:
10573:
10569:
10565:
10561:
10557:
10553:
10549:
10546:
10543:
10542:amitriptyline
10539:
10536:
10533:
10529:
10525:
10521:
10520:esmirtazapine
10517:
10513:
10509:
10506:
10504:
10501:
10499:
10496:
10494:
10491:
10489:
10486:
10483:
10479:
10478:triazoledione
10475:
10471:
10467:
10463:
10459:
10455:
10452:
10450:
10447:
10445:
10442:
10440:
10437:
10435:
10432:
10430:
10427:
10425:
10422:
10420:
10417:
10415:
10412:
10410:
10407:
10405:
10402:
10400:
10397:
10395:
10392:
10390:
10387:
10385:
10382:
10380:
10379:Naftidrofuryl
10377:
10375:
10372:
10370:
10367:
10365:
10362:
10360:
10357:
10355:
10352:
10350:
10347:
10345:
10342:
10340:
10337:
10335:
10332:
10330:
10327:
10325:
10322:
10320:
10317:
10314:
10310:
10306:
10302:
10298:
10294:
10290:
10286:
10283:
10281:
10278:
10276:
10273:
10271:
10268:
10266:
10263:
10261:
10258:
10256:
10253:
10250:
10246:
10242:
10238:
10234:
10230:
10226:
10222:
10218:
10214:
10210:
10206:
10202:
10198:
10194:
10190:
10186:
10182:
10178:
10174:
10173:brexpiprazole
10170:
10166:
10162:
10158:
10154:
10151:
10149:
10146:
10143:
10139:
10135:
10131:
10127:
10124:
10122:
10119:
10117:
10114:
10112:
10109:
10107:
10104:
10102:
10099:
10096:
10095:
10092:
10085:
10081:
10077:
10073:
10069:
10065:
10061:
10057:
10053:
10049:
10045:
10042:
10040:
10037:
10035:
10032:
10030:
10027:
10024:
10020:
10016:
10012:
10009:
10006:
10002:
9998:
9995:
9993:
9990:
9988:
9985:
9983:
9980:
9978:
9975:
9973:
9970:
9968:
9965:
9963:
9960:
9957:
9953:
9949:
9945:
9941:
9938:
9936:
9933:
9931:
9928:
9926:
9923:
9921:
9918:
9915:
9911:
9907:
9903:
9899:
9895:
9891:
9887:
9883:
9879:
9875:
9871:
9867:
9863:
9862:bromocriptine
9859:
9855:
9851:
9848:
9846:
9843:
9840:
9836:
9832:
9828:
9824:
9821:
9819:
9816:
9814:
9811:
9809:
9806:
9804:
9801:
9799:
9796:
9793:
9789:
9785:
9781:
9777:
9773:
9769:
9765:
9762:
9759:
9755:
9751:
9747:
9743:
9739:
9736:
9734:
9731:
9729:
9726:
9723:
9719:
9715:
9711:
9707:
9703:
9699:
9696:
9693:
9689:
9685:
9681:
9677:
9673:
9669:
9665:
9661:
9657:
9653:
9650:
9649:
9646:
9643:
9641:
9634:
9631:
9629:
9622:
9608:
9605:
9603:
9600:
9597:
9596:
9593:
9586:
9582:
9579:
9576:
9572:
9568:
9564:
9561:
9559:
9556:
9554:
9551:
9549:
9546:
9543:
9540:
9536:
9532:
9531:bromocriptine
9528:
9525:
9523:
9520:
9518:
9515:
9512:
9511:
9508:
9505:
9503:
9496:
9486:
9482:
9478:
9474:
9471:
9468:
9467:
9464:
9458:
9455:
9452:
9451:
9448:
9441:
9437:
9434:
9431:
9427:
9424:
9422:
9419:
9416:
9412:
9409:
9407:
9404:
9401:
9400:
9397:
9394:
9392:
9385:
9374:
9370:
9366:
9362:
9359:
9357:
9354:
9351:
9350:
9347:
9341:
9338:
9336:
9333:
9331:
9328:
9326:
9323:
9321:
9318:
9316:
9313:
9311:
9308:
9306:
9303:
9301:
9298:
9296:
9293:
9291:
9288:
9286:
9283:
9280:
9276:
9273:
9271:
9268:
9266:
9263:
9261:
9258:
9255:
9254:
9251:
9244:
9240:
9236:
9232:
9228:
9224:
9220:
9217:
9214:
9210:
9206:
9202:
9198:
9194:
9190:
9186:
9182:
9178:
9175:
9173:
9170:
9168:
9165:
9163:
9160:
9158:
9155:
9153:
9150:
9148:
9145:
9143:
9140:
9138:
9135:
9132:
9128:
9124:
9120:
9116:
9112:
9111:bromocriptine
9108:
9105:
9103:
9100:
9098:
9095:
9093:
9090:
9087:
9086:
9083:
9080:
9078:
9071:
9060:
9056:
9052:
9048:
9045:
9042:
9041:
9038:
9032:
9029:
9027:
9024:
9022:
9019:
9017:
9014:
9012:
9009:
9007:
9004:
9002:
8999:
8997:
8994:
8991:
8987:
8984:
8982:
8979:
8976:
8972:
8968:
8964:
8960:
8956:
8952:
8948:
8947:Beta blockers
8945:
8943:
8940:
8937:
8936:
8933:
8927:
8924:
8921:
8917:
8913:
8909:
8905:
8902:
8900:
8897:
8894:
8890:
8886:
8882:
8878:
8874:
8871:
8869:
8866:
8864:
8861:
8859:
8856:
8853:
8849:
8845:
8841:
8837:
8833:
8832:bromocriptine
8829:
8826:
8824:
8821:
8819:
8816:
8814:
8811:
8809:
8806:
8804:
8801:
8799:
8796:
8794:
8791:
8788:
8787:
8784:
8781:
8779:
8772:
8761:
8757:
8754:
8752:
8749:
8747:
8744:
8741:
8740:
8737:
8731:
8728:
8726:
8723:
8721:
8718:
8716:
8713:
8711:
8708:
8706:
8703:
8701:
8698:
8696:
8693:
8691:
8688:
8686:
8683:
8681:
8678:
8676:
8673:
8671:
8668:
8666:
8663:
8661:
8658:
8656:
8653:
8651:
8648:
8646:
8643:
8641:
8638:
8636:
8633:
8631:
8628:
8625:
8621:
8618:
8616:
8613:
8611:
8608:
8606:
8603:
8600:
8596:
8592:
8588:
8584:
8580:
8576:
8572:
8568:
8567:cyanopindolol
8564:
8560:
8556:
8555:Beta blockers
8553:
8551:
8548:
8545:
8541:
8537:
8533:
8530:
8527:
8526:
8523:
8517:
8514:
8512:
8509:
8507:
8504:
8502:
8499:
8497:
8494:
8492:
8489:
8486:
8482:
8478:
8474:
8470:
8466:
8462:
8458:
8454:
8450:
8447:
8445:
8442:
8440:
8437:
8435:
8432:
8430:
8427:
8425:
8422:
8420:
8417:
8415:
8412:
8410:
8407:
8405:
8402:
8400:
8397:
8395:
8392:
8390:
8387:
8385:
8382:
8380:
8377:
8375:
8372:
8370:
8367:
8365:
8362:
8360:
8357:
8355:
8352:
8350:
8347:
8345:
8342:
8340:
8337:
8335:
8332:
8330:
8327:
8325:
8322:
8320:
8317:
8315:
8312:
8310:
8307:
8305:
8302:
8300:
8297:
8295:
8292:
8290:
8287:
8284:
8280:
8276:
8272:
8268:
8264:
8260:
8256:
8252:
8251:bromocriptine
8248:
8245:
8243:
8240:
8238:
8235:
8233:
8230:
8228:
8225:
8223:
8220:
8218:
8215:
8213:
8210:
8208:
8205:
8203:
8200:
8197:
8193:
8189:
8185:
8181:
8177:
8174:
8171:
8167:
8163:
8159:
8155:
8151:
8150:brexpiprazole
8147:
8143:
8139:
8136:
8133:
8129:
8125:
8124:triazoledione
8121:
8117:
8113:
8109:
8105:
8102:
8100:
8097:
8095:
8092:
8090:
8087:
8084:
8083:
8080:
8077:
8075:
8068:
8065:
8063:
8056:
8052:
8049:
8042:
8037:
8035:
8030:
8028:
8023:
8022:
8019:
8007:
8004:
8002:
7999:
7997:
7994:
7991:
7990:
7987:
7977:
7974:
7972:
7969:
7967:
7964:
7962:
7959:
7957:
7954:
7952:
7949:
7948:
7946:
7942:
7936:
7933:
7931:
7928:
7926:
7920:
7918:
7915:
7913:
7910:
7908:
7905:
7904:
7902:
7898:
7895:
7893:
7886:
7876:
7873:
7871:
7868:
7866:
7863:
7861:
7858:
7856:
7853:
7851:
7848:
7846:
7843:
7841:
7838:
7836:
7833:
7831:
7828:
7826:
7823:
7821:
7818:
7816:
7813:
7811:
7808:
7806:
7803:
7801:
7798:
7796:
7793:
7791:
7788:
7786:
7783:
7781:
7778:
7776:
7773:
7771:
7768:
7766:
7763:
7762:
7760:
7756:
7750:
7747:
7745:
7742:
7740:
7734:
7732:
7729:
7727:
7724:
7722:
7719:
7717:
7714:
7712:
7709:
7707:
7704:
7703:
7701:
7697:
7694:
7692:
7685:
7675:
7672:
7670:
7667:
7665:
7662:
7660:
7657:
7655:
7652:
7650:
7647:
7645:
7642:
7640:
7637:
7635:
7632:
7630:
7627:
7625:
7622:
7620:
7617:
7615:
7612:
7610:
7607:
7605:
7602:
7600:
7597:
7595:
7592:
7590:
7587:
7585:
7582:
7580:
7577:
7575:
7572:
7570:
7567:
7565:
7562:
7560:
7557:
7555:
7552:
7550:
7547:
7545:
7542:
7540:
7537:
7535:
7532:
7530:
7527:
7526:
7524:
7520:
7514:
7511:
7509:
7503:
7501:
7498:
7496:
7493:
7491:
7488:
7486:
7483:
7481:
7478:
7476:
7473:
7472:
7470:
7466:
7463:
7461:
7454:
7444:
7441:
7439:
7436:
7434:
7431:
7429:
7426:
7424:
7421:
7419:
7416:
7414:
7411:
7409:
7406:
7404:
7401:
7398:
7397:
7393:
7389:
7385:
7381:
7377:
7373:
7369:
7365:
7361:
7358:
7355:
7351:
7350:protriptyline
7347:
7346:nortriptyline
7343:
7339:
7335:
7331:
7327:
7323:
7319:
7315:
7311:
7310:amitriptyline
7307:
7304:
7301:
7297:
7293:
7289:
7285:
7281:
7277:
7274:
7271:
7270:triazoledione
7267:
7263:
7259:
7255:
7252:
7249:
7246:
7242:
7238:
7234:
7230:
7226:
7222:
7218:
7214:
7213:brilaroxazine
7210:
7209:brexpiprazole
7206:
7202:
7198:
7195:
7192:
7191:
7188:
7185:
7183:
7180:
7178:
7175:
7173:
7170:
7168:
7165:
7163:
7160:
7158:
7155:
7153:
7150:
7148:
7145:
7143:
7140:
7138:
7135:
7133:
7130:
7128:
7125:
7123:
7120:
7118:
7115:
7113:
7110:
7108:
7105:
7103:
7100:
7098:
7095:
7093:
7090:
7088:
7085:
7083:
7080:
7078:
7075:
7073:
7072:Levocabastine
7070:
7068:
7065:
7063:
7060:
7058:
7055:
7053:
7050:
7048:
7045:
7043:
7040:
7038:
7035:
7033:
7030:
7028:
7025:
7023:
7022:Desloratadine
7020:
7018:
7015:
7013:
7010:
7008:
7005:
7003:
7000:
6998:
6995:
6993:
6990:
6988:
6985:
6983:
6980:
6978:
6975:
6973:
6970:
6968:
6965:
6963:
6960:
6958:
6955:
6953:
6950:
6948:
6945:
6942:
6941:
6938:
6935:
6933:
6930:
6928:
6925:
6923:
6920:
6918:
6915:
6913:
6912:Thenyldiamine
6910:
6908:
6905:
6903:
6900:
6898:
6897:Pyrrobutamine
6895:
6893:
6890:
6888:
6885:
6883:
6880:
6878:
6875:
6873:
6870:
6868:
6865:
6863:
6860:
6858:
6855:
6853:
6850:
6848:
6845:
6843:
6840:
6838:
6835:
6833:
6830:
6828:
6825:
6823:
6822:Methapyrilene
6820:
6818:
6817:Methafurylene
6815:
6813:
6810:
6808:
6805:
6803:
6800:
6798:
6795:
6793:
6790:
6788:
6785:
6783:
6780:
6778:
6775:
6773:
6770:
6768:
6765:
6763:
6760:
6758:
6755:
6753:
6750:
6748:
6745:
6743:
6740:
6738:
6735:
6733:
6730:
6728:
6725:
6723:
6720:
6718:
6715:
6713:
6710:
6708:
6705:
6703:
6700:
6698:
6695:
6693:
6690:
6688:
6685:
6683:
6680:
6678:
6675:
6673:
6670:
6668:
6665:
6663:
6660:
6658:
6655:
6653:
6650:
6648:
6645:
6643:
6640:
6638:
6635:
6633:
6630:
6628:
6625:
6623:
6622:Carbinoxamine
6620:
6618:
6615:
6613:
6610:
6608:
6605:
6603:
6600:
6598:
6595:
6593:
6590:
6588:
6585:
6583:
6580:
6578:
6575:
6573:
6570:
6568:
6565:
6562:
6561:
6559:
6555:
6549:
6546:
6544:
6538:
6536:
6533:
6531:
6528:
6526:
6523:
6521:
6518:
6517:
6515:
6511:
6508:
6506:
6499:
6495:
6492:
6485:
6480:
6478:
6473:
6471:
6466:
6465:
6462:
6450:
6447:
6445:
6442:
6440:
6437:
6435:
6432:
6430:
6427:
6425:
6422:
6420:
6417:
6415:
6412:
6410:
6407:
6405:
6402:
6401:
6399:
6396:
6391:
6385:
6384:Phenbenzamine
6382:
6379:
6375:
6371:
6368:
6367:
6365:
6361:
6355:
6352:
6350:
6347:
6345:
6342:
6340:
6337:
6335:
6332:
6330:
6327:
6325:
6322:
6319:
6315:
6311:
6307:
6304:
6301:
6300:
6297:
6294:
6292:
6289:
6287:
6284:
6282:
6279:
6277:
6274:
6272:
6269:
6267:
6264:
6262:
6258:
6257:
6253:
6252:
6249:
6246:
6244:
6241:
6239:
6236:
6234:
6233:Desloratadine
6231:
6229:
6226:
6224:
6221:
6219:
6216:
6213:
6212:amitriptyline
6209:
6205:
6204:
6200:
6199:
6197:
6195:
6191:
6185:
6182:
6180:
6177:
6175:
6174:Phenbenzamine
6172:
6170:
6169:Methapyrilene
6167:
6165:
6162:
6160:
6157:
6155:
6152:
6150:
6147:
6146:
6144:
6142:
6138:
6132:
6129:
6127:
6124:
6122:
6121:Pyrrobutamine
6119:
6117:
6114:
6112:
6109:
6107:
6104:
6102:
6099:
6096:
6095:
6092:
6089:
6086:
6082:
6079:
6076:
6072:
6069:
6067:
6064:
6062:
6059:
6056:
6055:
6052:
6049:
6047:
6044:
6042:
6039:
6037:
6034:
6032:
6029:
6027:
6024:
6022:
6019:
6015:
6012:
6011:
6010:
6007:
6005:
6001:
6000:
5996:
5995:
5992:
5989:
5987:
5983:
5982:
5978:
5977:
5974:
5971:
5969:
5966:
5964:
5961:
5959:
5956:
5953:
5949:
5946:
5944:
5941:
5939:
5936:
5934:
5933:Carbinoxamine
5931:
5929:
5926:
5923:
5922:
5920:
5918:
5914:
5908:
5905:
5903:
5900:
5898:
5895:
5893:
5890:
5888:
5885:
5883:
5880:
5879:
5877:
5868:
5864:
5859:
5855:
5848:
5843:
5841:
5836:
5834:
5829:
5828:
5825:
5809:
5805:
5800:
5795:
5790:
5785:
5781:
5777:
5773:
5766:
5747:
5743:
5739:
5735:
5731:
5727:
5723:
5719:
5715:
5708:
5701:
5693:
5689:
5684:
5679:
5675:
5671:
5667:
5663:
5659:
5652:
5636:
5632:
5628:
5624:
5620:
5616:
5612:
5608:
5604:
5600:
5593:
5591:
5582:
5578:
5573:
5568:
5564:
5560:
5556:
5552:
5548:
5541:
5539:
5522:
5518:
5512:
5496:
5492:
5486:
5470:
5466:
5460:
5444:
5440:
5434:
5418:
5414:
5408:
5400:
5396:
5392:
5388:
5384:
5380:
5376:
5372:
5365:
5357:
5351:
5335:
5331:
5325:
5309:
5305:
5299:
5283:
5279:
5273:
5257:
5253:
5252:
5247:
5240:
5224:
5220:
5216:
5210:
5194:
5190:
5186:
5180:
5164:
5160:
5156:
5150:
5134:
5130:
5126:
5120:
5104:
5100:
5096:
5090:
5074:
5070:
5066:
5062:
5058:
5054:
5050:
5045:
5037:
5021:
5017:
5016:Inxight Drugs
5013:
5007:
4991:
4987:
4983:
4977:
4961:
4957:
4951:
4947:
4943:
4936:
4920:
4916:
4910:
4906:
4902:
4898:
4894:
4887:
4879:
4875:
4871:
4867:
4863:
4859:
4852:
4850:
4841:
4837:
4833:
4829:
4825:
4821:
4817:
4813:
4805:
4803:
4794:
4790:
4786:
4782:
4778:
4774:
4770:
4766:
4759:
4757:
4755:
4753:
4751:
4749:
4747:
4738:
4734:
4730:
4726:
4722:
4718:
4714:
4710:
4703:
4695:
4691:
4687:
4683:
4679:
4675:
4671:
4667:
4660:
4652:
4648:
4643:
4638:
4634:
4630:
4626:
4622:
4618:
4611:
4603:
4599:
4595:
4591:
4587:
4583:
4579:
4575:
4568:
4560:
4556:
4551:
4546:
4541:
4536:
4532:
4528:
4527:Front Immunol
4524:
4517:
4509:
4505:
4501:
4497:
4493:
4489:
4482:
4463:
4456:
4450:
4434:
4430:
4424:
4420:
4416:
4412:
4408:
4401:
4393:
4389:
4385:
4381:
4374:
4365:
4360:
4356:
4352:
4348:
4341:
4333:
4329:
4324:
4319:
4315:
4311:
4307:
4300:
4292:
4288:
4284:
4280:
4276:
4272:
4269:(5): 521–30.
4268:
4264:
4257:
4249:
4243:
4239:
4235:
4231:
4224:
4216:
4212:
4207:
4202:
4197:
4192:
4188:
4184:
4180:
4173:
4171:
4162:
4158:
4153:
4148:
4143:
4138:
4134:
4130:
4126:
4119:
4111:
4107:
4103:
4099:
4095:
4091:
4084:
4076:
4072:
4067:
4062:
4057:
4052:
4048:
4044:
4040:
4033:
4025:
4021:
4017:
4013:
4009:
4005:
3998:
3996:
3987:
3981:
3977:
3973:
3966:
3958:
3952:
3948:
3944:
3937:
3929:
3925:
3920:
3915:
3911:
3907:
3903:
3899:
3895:
3888:
3880:
3874:
3870:
3866:
3859:
3851:
3847:
3842:
3837:
3832:
3827:
3823:
3819:
3818:J Inflamm Res
3815:
3808:
3806:
3804:
3802:
3793:
3789:
3784:
3779:
3775:
3771:
3767:
3760:
3758:
3741:
3737:
3731:
3715:
3711:
3705:
3697:
3693:
3689:
3685:
3678:
3670:
3666:
3662:
3658:
3654:
3650:
3643:
3641:
3639:
3619:
3612:
3606:
3604:
3584:
3577:
3571:
3569:
3560:
3556:
3552:
3548:
3541:
3534:
3521:
3517:
3513:
3509:
3505:
3501:
3497:
3493:
3486:
3478:
3474:
3470:
3463:
3461:
3459:
3457:
3448:
3444:
3439:
3434:
3430:
3426:
3422:
3418:
3414:
3407:
3405:
3403:
3401:
3392:
3388:
3384:
3380:
3376:
3372:
3368:
3364:
3357:
3355:
3353:
3336:
3332:
3328:
3322:
3320:
3318:
3301:
3297:
3291:
3287:
3283:
3279:
3278:
3271:
3269:
3260:
3256:
3253:(10): 29–31.
3252:
3248:
3241:
3233:
3229:
3225:
3221:
3214:
3198:
3194:
3188:
3172:
3168:
3162:
3160:
3158:
3148:
3143:
3139:
3135:
3131:
3124:
3116:
3112:
3107:
3102:
3099:(3): 309–27.
3098:
3094:
3090:
3083:
3075:
3071:
3067:
3063:
3056:
3054:
3045:
3041:
3036:
3031:
3026:
3021:
3017:
3013:
3009:
3002:
2994:
2990:
2986:
2982:
2978:
2974:
2967:
2959:
2953:
2949:
2945:
2941:
2934:
2927:
2923:
2919:
2914:
2909:
2904:
2899:
2896:: 1359–1369.
2895:
2891:
2887:
2880:
2878:
2869:
2865:
2861:
2857:
2853:
2849:
2845:
2841:
2834:
2826:
2822:
2817:
2812:
2808:
2804:
2800:
2796:
2792:
2785:
2769:
2765:
2759:
2740:
2736:
2729:
2723:
2707:
2703:
2697:
2695:
2693:
2673:
2666:
2660:
2644:
2640:
2636:
2632:
2628:
2624:
2617:
2609:
2605:
2601:
2597:
2593:
2589:
2585:
2578:
2570:
2566:
2562:
2558:
2554:
2550:
2546:
2542:
2535:
2527:
2523:
2518:
2513:
2508:
2503:
2499:
2495:
2491:
2484:
2476:
2472:
2467:
2462:
2457:
2452:
2448:
2444:
2440:
2433:
2431:
2429:
2419:
2414:
2411:(4): 287–90.
2410:
2406:
2402:
2395:
2387:
2383:
2378:
2373:
2369:
2365:
2361:
2357:
2353:
2346:
2344:
2342:
2333:
2326:
2318:
2314:
2310:
2306:
2302:
2298:
2294:
2290:
2283:
2281:
2279:
2270:
2266:
2261:
2256:
2251:
2246:
2242:
2238:
2234:
2227:
2225:
2216:
2212:
2208:
2204:
2200:
2196:
2192:
2188:
2181:
2173:
2169:
2164:
2159:
2154:
2149:
2146:(7): e27093.
2145:
2141:
2137:
2130:
2122:
2118:
2114:
2110:
2106:
2102:
2098:
2094:
2087:
2085:
2083:
2081:
2079:
2077:
2068:
2064:
2060:
2054:
2052:
2050:
2048:
2046:
2029:
2025:
2021:
2015:
1999:
1995:
1994:
1993:Health Canada
1989:
1983:
1967:
1963:
1962:
1961:Health Canada
1957:
1951:
1949:
1932:
1928:
1924:
1918:
1916:
1914:
1912:
1907:
1899:
1898:experiments.
1897:
1896:
1891:
1887:
1877:
1875:
1865:
1863:
1859:
1855:
1854:disinhibition
1851:
1847:
1843:
1839:
1835:
1831:
1828:, which is a
1827:
1823:
1819:
1814:
1812:
1807:
1805:
1801:
1786:
1784:
1780:
1776:
1772:
1769:
1764:
1760:
1756:
1753:
1749:
1745:
1730:
1728:
1723:
1719:
1709:
1707:
1696:
1677:
1668:
1664:
1662:
1658:
1648:
1646:
1642:
1638:
1634:
1630:
1626:
1622:
1618:
1607:
1605:
1601:
1576:
1572:
1568:
1563:
1554:
1552:
1548:
1544:
1540:
1536:
1533:, especially
1532:
1527:
1524:
1519:
1517:
1513:
1509:
1504:
1502:
1498:
1494:
1490:
1486:
1482:
1478:
1474:
1473:degranulation
1469:
1467:
1462:
1458:
1453:
1451:
1440:
1433:
1423:
1418:
1414:
1412:
1408:
1400:
1393:
1389:
1385:
1384:antihistamine
1382:
1372:
1369:
1366:
1361:
1359:
1354:
1352:
1348:
1344:
1340:
1339:amifampridine
1335:
1333:
1332:benzphetamine
1329:
1324:
1322:
1311:
1307:
1305:
1301:
1297:
1293:
1289:
1285:
1281:
1277:
1273:
1269:
1265:
1261:
1257:
1253:
1249:
1243:
1241:
1237:
1233:
1229:
1224:
1222:
1218:
1214:
1210:
1206:
1202:
1198:
1194:
1189:
1180:
1178:
1174:
1170:
1166:
1162:
1158:
1154:
1150:
1146:
1141:
1139:
1135:
1131:
1130:eye discharge
1127:
1117:
1114:
1110:
1105:
1100:
1098:
1094:
1090:
1087:(in adults),
1086:
1082:
1078:
1073:
1064:
1062:
1058:
1054:
1050:
1046:
1042:
1037:
1035:
1030:
1028:
1024:
1019:
1015:
1013:
1008:
1004:
1000:
996:
992:
988:
984:
980:
976:
972:
968:
964:
960:
955:
951:
949:
941:
937:
933:
930:
926:
922:
921:
920:
918:
914:
904:
902:
898:
892:
890:
886:
882:
878:
874:
870:
866:
865:smooth muscle
862:
853:
851:
847:
843:
839:
835:
831:
827:
823:
819:
815:
811:
807:
803:
799:
798:antihistamine
795:
785:
778:
769:
764:
759:
758:
755:
748:
739:
738:
735:
728:
721:
717:
716:
714:
711:
706:
699:
697:
693:
669:
667:
663:
658:
654:
650:
647:
645:
643:ECHA InfoCard
639:
631:
627:
626:DTXSID7023190
623:
622:
620:
611:
607:
600:
595:
592:
588:
587:
585:
583:
579:
572:
567:
564:
560:
559:
557:
555:
551:
544:
539:
536:
532:
531:
529:
527:
523:
516:
511:
508:
504:
503:
501:
499:
495:
488:
483:
480:
476:
475:
473:
471:
467:
460:
455:
452:
448:
447:
445:
443:
439:
432:
428:
427:
425:
423:
419:
412:
407:
404:
400:
399:
397:
390:
386:
379:
374:
371:
367:
366:
364:
362:
358:
350:
345:
344:
341:
334:
329:
325:
323:
316:
313:
310:
308:
304:
300:
298:
294:
290:
288:
284:
280:
276:
265:
255:
252:
242:
240:
231:
230:
228:
226:
222:
217:
209:
204:
199:
194:
191:
190:
188:
186:
182:
178:
174:
171:
169:
163:
157:
148:
147:
145:
143:
137:
130:
125:
116:
115:
113:
111:
107:
103:
99:
97:
93:
89:
85:
83:
79:
75:
66:
62:
58:
54:
52:
48:
45:Clinical data
43:
39:
34:
26:
22:
14844:Siltenzepine
14739:Benzoctamine
14680:Rispenzepine
14612:Trifluthepin
14582:Thioridazine
14547:Prothipendyl
14507:Perphenazine
14482:Oxyprothepin
14477:Oxyclothepin
14437:Mesoridazine
14402:Homopipramol
14392:Fluphenazine
14327:Clocapramine
14302:Carpipramine
14292:Butaperazine
14249:Thiazinamium
14239:Propiomazine
14234:Promethazine
14224:Phenindamine
14209:Methdilazine
14189:Latrepirdine
14183:
14179:Isothipendyl
14101:Trimipramine
14096:Tienopramine
14071:Quinupramine
14041:Octriptyline
13936:Intriptyline
13921:Homopipramol
13846:Cotriptyline
13841:Clomipramine
13826:Cianopramine
13821:Butriptyline
13749:Thioxanthene
13729:Dibenzoxepin
13627:
13618:
13605:
13596:
13587:
13578:
13567:
13566:
13522:
13510:Vortioxetine
13496:fluphenazine
13470:clomipramine
13365:JNJ-18038683
13355:methysergide
13266:fluperlapine
13246:aripiprazole
13235:Antagonists:
13234:
13199:frovatriptan
13131:
13072:
13037:clomipramine
12945:Landipirdine
12935:Idalopirdine
12920:Cerlapirdine
12867:fluperlapine
12851:aripiprazole
12839:Antagonists:
12838:
12747:methysergide
12711:
12672:methysergide
12660:
12631:Antagonists:
12630:
12581:
12515:Antagonists:
12514:
12457:Prucalopride
12403:
12361:
12339:Vortioxetine
12253:Palonosetron
12142:Antagonists:
12141:
12019:
11951:
11933:thioridazine
11769:Medifoxamine
11758:
11724:methysergide
11676:Deramciclane
11630:paliperidone
11614:fluperlapine
11585:Antagonists:
11584:
11464:aripiprazole
11347:ergine (LSA)
11190:
11153:
11058:Sarpogrelate
10908:aripiprazole
10892:Antagonists:
10891:
10768:methysergide
10703:fenfluramine
10687:Amphetamines
10673:
10632:
10610:Volinanserin
10596:thioridazine
10568:perphenazine
10556:fluphenazine
10498:Teniloxazine
10449:Sarpogrelate
10439:Roluperidone
10409:Pimavanserin
10389:Nelotanserin
10364:Medifoxamine
10349:Landipirdine
10309:methysergide
10280:Eplivanserin
10270:Deramciclane
10225:paliperidone
10193:fluperlapine
10181:clocapramine
10177:carpipramine
10161:aripiprazole
10137:
10106:5-MeO-NBpBrT
10098:Antagonists:
10097:
9870:ergine (LSA)
9692:2CBFly-NBOMe
9651:
9599:Antagonists:
9598:
9542:methysergide
9513:
9469:
9454:Antagonists:
9453:
9415:methysergide
9402:
9352:
9257:Antagonists:
9256:
9213:zolmitriptan
9197:frovatriptan
9131:methysergide
9088:
9043:
8939:Antagonists:
8938:
8926:Vortioxetine
8893:zolmitriptan
8848:methysergide
8789:
8742:
8710:Spiroxatrine
8529:Antagonists:
8528:
8279:methysergide
8196:tandospirone
8142:aripiprazole
8132:vortioxetine
8085:
7966:Thioperamide
7870:Thioperamide
7810:Clobenpropit
7731:Immethridine
7634:Ramixotidine
7604:Niperotidine
7569:Isolamtidine
7529:Bisfentidine
7438:Trelnarizine
7418:Flotrenizine
7399:
7388:thioridazine
7380:perphenazine
7372:fluphenazine
7368:flupenthixol
7354:trimipramine
7318:clomipramine
7314:butriptyline
7300:oxaprotiline
7229:paliperidone
7201:aripiprazole
7193:
7137:Piclopastine
7067:Latrepirdine
7061:
7057:Flezelastine
7052:Fexofenadine
7037:Efletirizine
6943:
6937:Triprolidine
6927:Tolpropamine
6922:Thonzylamine
6917:Thiazinamium
6892:Propiomazine
6887:Promethazine
6857:Phenindamine
6837:Orphenadrine
6827:Methdilazine
6792:Isothipendyl
6742:Etodroxizine
6672:Cloperastine
6563:
6449:Promethazine
6439:Isothipendyl
6369:
6349:Phenindamine
6329:Latrepirdine
6318:trimipramine
6302:
6296:Promethazine
6286:Methdilazine
6276:Isothipendyl
6254:
6237:
6201:
6131:Triprolidine
6097:
6057:
6036:Etodroxizine
5997:
5986:Fexofenadine
5979:
5973:Orphenadrine
5924:
5779:
5775:
5765:
5755:24 September
5753:. Retrieved
5717:
5713:
5700:
5665:
5661:
5651:
5639:. Retrieved
5606:
5602:
5557:(1): 83–89.
5554:
5550:
5525:. Retrieved
5511:
5499:. Retrieved
5485:
5473:. Retrieved
5459:
5447:. Retrieved
5433:
5421:. Retrieved
5407:
5374:
5370:
5364:
5355:
5350:
5338:. Retrieved
5324:
5312:. Retrieved
5298:
5286:. Retrieved
5272:
5260:. Retrieved
5249:
5239:
5227:. Retrieved
5218:
5209:
5197:. Retrieved
5188:
5179:
5167:. Retrieved
5158:
5149:
5137:. Retrieved
5128:
5119:
5107:. Retrieved
5098:
5089:
5077:. Retrieved
5052:
5048:
5036:
5024:. Retrieved
5015:
5006:
4994:. Retrieved
4976:
4964:. Retrieved
4945:
4935:
4923:. Retrieved
4896:
4886:
4861:
4857:
4818:(1): 36–40.
4815:
4811:
4771:(1): 31–47.
4768:
4764:
4712:
4708:
4702:
4669:
4665:
4659:
4624:
4620:
4610:
4577:
4573:
4567:
4530:
4526:
4516:
4491:
4487:
4481:
4469:. Retrieved
4449:
4437:. Retrieved
4410:
4400:
4383:
4379:
4373:
4354:
4350:
4340:
4316:(2): 153–6.
4313:
4309:
4299:
4266:
4262:
4256:
4229:
4223:
4186:
4182:
4132:
4128:
4118:
4096:(5): 234–8.
4093:
4089:
4083:
4046:
4042:
4032:
4007:
4004:Exp Dermatol
4003:
3975:
3965:
3946:
3936:
3901:
3897:
3887:
3868:
3858:
3821:
3817:
3773:
3769:
3744:. Retrieved
3730:
3718:. Retrieved
3704:
3687:
3683:
3677:
3652:
3648:
3625:. Retrieved
3590:. Retrieved
3553:: 25. 2013.
3550:
3546:
3540:
3531:
3524:. Retrieved
3499:
3495:
3485:
3468:
3420:
3416:
3366:
3362:
3339:. Retrieved
3330:
3304:. Retrieved
3276:
3250:
3246:
3240:
3223:
3219:
3213:
3201:. Retrieved
3187:
3175:. Retrieved
3137:
3133:
3123:
3096:
3092:
3082:
3065:
3061:
3015:
3011:
3001:
2976:
2972:
2966:
2939:
2933:
2925:
2893:
2889:
2843:
2839:
2833:
2798:
2794:
2784:
2772:. Retrieved
2758:
2746:. Retrieved
2722:
2710:. Retrieved
2679:. Retrieved
2659:
2647:. Retrieved
2630:
2626:
2616:
2591:
2587:
2577:
2544:
2540:
2534:
2497:
2493:
2483:
2446:
2442:
2408:
2404:
2394:
2359:
2355:
2331:
2325:
2292:
2288:
2240:
2236:
2190:
2186:
2180:
2143:
2139:
2129:
2096:
2092:
2062:
2032:. Retrieved
2023:
2014:
2002:. Retrieved
1991:
1982:
1970:. Retrieved
1959:
1935:. Retrieved
1926:
1893:
1883:
1871:
1846:hypothalamus
1815:
1808:
1797:
1763:demethylated
1744:norketotifen
1741:
1738:Norketotifen
1715:
1702:
1687:
1665:
1654:
1608:
1593:
1539:norketotifen
1528:
1520:
1505:
1477:leukotrienes
1470:
1454:
1419:
1415:
1411:leukotrienes
1378:
1375:Pharmacology
1370:
1362:
1355:
1336:
1325:
1317:
1314:Interactions
1308:
1292:coagulopathy
1260:pancreatitis
1244:
1225:
1190:
1186:
1142:
1136:, increased
1123:
1120:Side effects
1101:
1074:
1070:
1038:
1031:
1020:
1016:
1003:immune cells
1001:, which are
983:mastocytosis
956:
952:
945:
917:fumaric acid
910:
907:Medical uses
893:
885:leukotrienes
854:
830:mastocytosis
793:
792:
781:
459:DBSALT001856
348:
319:Elimination
225:Legal status
219:Legal status
110:License data
25:
14922:Piperidines
14859:Zolenzepine
14849:Telenzepine
14819:Pirenzepine
14804:Pipazethate
14789:Nuvenzepine
14774:Fluradoline
14764:Darenzepine
14703:Tropatepine
14698:Profenamine
14645:Dizocilpine
14597:Traboxopine
14587:Thiothixene
14527:Pipotiazine
14512:Periciazine
14497:Perathiepin
14457:Mosapramine
14397:Gevotroline
14387:Flupentixol
14377:Flumezapine
14357:Doclothepin
14352:Cyanothepin
14337:Clorotepine
14272:Alimemazine
14229:Pimethixene
14219:Oxomemazine
14214:Olopatadine
14204:Mequitazine
14199:Mebhydrolin
14164:Fenethazine
14159:Etymemazine
14129:Clobenzepam
14061:Propizepine
14056:Pirandamine
14036:Noxiptiline
14001:Mirtazapine
13991:Metapramine
13976:Mariptiline
13971:Maprotiline
13956:Lofepramine
13946:Ketipramine
13901:Enprazepine
13886:Dimetacrine
13831:Ciclazindol
13580:Adrenergics
13540:Piperazines
13456:mirtazapine
13448:maprotiline
13359:sergolexole
13351:metergoline
13347:mesulergine
13327:cabergoline
13306:EGIS-12,233
13286:ziprasidone
13274:risperidone
13258:clorotepine
13242:amisulpride
13205:Tryptamines
13098:Piperazines
12955:Masupirdine
12925:EGIS-12,233
12871:iloperidone
12859:clorotepine
12763:Tryptamines
12743:metergoline
12739:mesulergine
12678:Piperazines
12668:metergoline
12608:Tryptamines
12492:Usmarapride
12447:Minesapride
12422:Cinitapride
12370:Piperazines
12329:sevoflurane
12306:Tropisetron
12301:Tropanserin
12290:mirtazapine
12248:Ondansetron
12228:Granisetron
12203:Cilansetron
12188:Batanopride
12155:Arazasetron
12150:Anpirtoline
12089:Tryptamines
12051:Piperazines
11929:pipamperone
11878:mirtazapine
11870:maprotiline
11844:SDZ SER-082
11794:Propranolol
11784:Pirenperone
11734:Etoperidone
11728:sergolexole
11720:metergoline
11716:mesulergine
11691:Eltoprazine
11646:ziprasidone
11638:risperidone
11618:iloperidone
11606:clorotepine
11593:Agomelatine
11588:Adatanserin
11557:Vabicaserin
11511:Tryptamines
11460:Piperazines
11339:cabergoline
11115:mirtazapine
11093:SDZ SER-082
11043:Rauwolscine
11033:Propranolol
11023:Pirenperone
10992:mesulergine
10952:ziprasidone
10948:risperidone
10940:pipamperone
10920:cariprazine
10904:amisulpride
10895:Agomelatine
10830:Tryptamines
10805:Piperazines
10748:cabergoline
10644:nicergoline
10600:thiothixene
10576:pipamperone
10560:haloperidol
10532:mirtazapine
10524:maprotiline
10470:mepiprazole
10458:etoperidone
10429:Rauwolscine
10424:Pruvanserin
10414:Pirenperone
10329:Glemanserin
10324:Flibanserin
10313:sergolexole
10305:metergoline
10301:mesulergine
10245:ziprasidone
10241:zicronapine
10233:risperidone
10217:ocaperidone
10213:mosapramine
10201:iloperidone
10197:gevotroline
10185:clorotepine
10169:blonanserin
10134:hydroxyzine
10116:Adatanserin
10044:Tryptamines
10011:Piperazines
9866:cabergoline
9684:2CBCB-NBOMe
9680:25TFM-NBOMe
9581:Tryptamines
9575:sumatriptan
9571:naratriptan
9436:Tryptamines
9356:Acetryptine
9340:Ziprasidone
9279:metergoline
9219:Tryptamines
9209:sumatriptan
9205:rizatriptan
9201:naratriptan
9189:donitriptan
9181:almotriptan
9115:cabergoline
9051:cabergoline
8990:metergoline
8971:propranolol
8904:Tryptamines
8889:sumatriptan
8881:donitriptan
8823:Eltoprazine
8793:Anpirtoline
8746:Acetryptine
8695:SDZ 216-525
8635:Flopropione
8624:metergoline
8595:propranolol
8540:risperidone
8536:iloperidone
8449:Tryptamines
8394:Rauwolscine
8384:Pardoprunox
8324:Flibanserin
8255:cabergoline
8242:Enciprazine
8237:Eltoprazine
8217:Cannabidiol
8192:perospirone
8170:ziprasidone
8154:cariprazine
8108:etoperidone
8099:Amphetamine
8094:Adatanserin
7951:JNJ-7777120
7944:Antagonists
7855:PF-03654746
7850:NNC 38-1049
7845:JNJ-5207852
7830:Impentamine
7795:Betahistine
7758:Antagonists
7711:Cipralisant
7674:Zolantidine
7664:Venritidine
7599:Mifentidine
7544:Dalcotidine
7522:Antagonists
7500:Impromidine
7428:Napactadine
7392:thiothixene
7342:lofepramine
7322:desipramine
7296:mirtazapine
7288:maprotiline
7241:ziprasidone
7237:risperidone
7221:iloperidone
7177:Terfenadine
7172:Temelastine
7122:Olopatadine
7112:Noberastine
7102:Mizolastine
7097:Mebhydrolin
7092:Mapinastine
7082:Linetastine
6997:Carebastine
6982:Bepotastine
6967:Bamirastine
6947:Acrivastine
6907:Thenalidine
6872:Pimethixene
6862:Pheniramine
6847:Oxomemazine
6812:Mequitazine
6802:Medrylamine
6782:Hydroxyzine
6762:Flunarizine
6757:Fenethazine
6752:Etymemazine
6717:Dimetindene
6692:Decloxizine
6667:Clocinizine
6662:Clobenzepam
6652:Cinnarizine
6597:Bepotastine
6572:Alimemazine
6557:Antagonists
6525:Betahistine
6424:Dimetindene
6354:Pimethixene
6339:Olopatadine
6334:Mebhydrolin
6314:mirtazapine
6291:Oxomemazine
6281:Mequitazine
6266:Fenethazine
6261:Alimemazine
6179:Thenalidine
6126:Quifenadine
6111:Dimetindene
6101:Acrivastine
6091:Pheniramine
6041:Hydroxyzine
6026:Cinnarizine
5991:Terfenadine
5902:Mizolastine
5314:5 September
5229:4 September
4996:16 November
4982:"Ketotifen"
4925:14 February
4471:14 February
4439:14 February
4090:Inflamm Res
4049:(9): 1338.
3824:: 927–939.
3363:Drug Safety
3306:22 November
3203:16 November
3177:16 November
3018:(7): 2039.
2973:Int Immunol
2712:16 November
2623:"Ketotifen"
1937:4 September
1759:hepatocytes
1699:Brand names
1501:neutrophils
1493:eosinophils
1358:thrombocyte
1328:amphetamine
1296:convulsions
1252:sleep apnea
1236:convulsions
1232:hypotension
1228:tachycardia
1161:anaphylaxis
1149:weight gain
1041:leukotriene
991:anaphylaxis
873:nerve cells
869:endothelium
703: g·mol
649:100.047.348
571:CHEBI:31750
563:CHEBI:92511
331:Identifiers
96:MedlinePlus
60:Other names
51:Trade names
14896:Categories
14839:Serazapine
14829:Pitrazepin
14814:Pinadoline
14769:Elanzepine
14759:Damotepine
14744:Carvedilol
14592:Tilozepine
14567:Tenilapine
14552:Quetiapine
14532:Piquindone
14487:Pentiapine
14472:Olanzapine
14447:Metitepine
14422:Lurasidone
14382:Fluotracen
14372:Flucindole
14342:Clotiapine
14322:Citatepine
14317:Ciclindole
14287:Butaclamol
14244:Rupatadine
14194:Loratadine
14154:Epinastine
14144:Deptropine
14139:Dacemazine
14091:Tianeptine
14086:Tampramine
14076:Spiroxepin
14051:Pipofezine
14021:Nordoxepin
13986:Melitracen
13926:Imipramine
13911:Fluotracen
13906:Fantridone
13881:Dibenzepin
13816:Batelapine
13811:Azepindole
13806:Aptazapine
13786:Amineptine
13694:Anthracene
13673:Tricyclics
13474:imipramine
13435:SSR-181507
13410:SB-656104A
13385:Ritanserin
13375:LY-215,840
13370:Ketanserin
13343:LY-215,840
13335:ergotamine
13319:amesergide
13296:Butaclamol
13282:tiospirone
13278:sertindole
13270:olanzapine
13145:Bifeprunox
13088:lergotrile
12985:Ro 63-0563
12980:Ro 04-6790
12975:Ritanserin
12940:Ketanserin
12879:tiospirone
12875:olanzapine
12826:WAY-208466
12821:WAY-181187
12815:tryptamine
12795:EMD-386088
12727:ergotamine
12649:Ritanserin
12593:ergotamine
12497:Velusetrag
12467:Renzapride
12349:Zatosetron
12268:Ricasetron
12263:Renzapride
12258:Ramosetron
12238:Lerisetron
12218:Dolasetron
12177:quetiapine
12173:olanzapine
12115:isoflurane
11939:Xylamidine
11862:aptazapine
11799:Ritanserin
11779:Nefazodone
11754:Ketanserin
11749:Irindalone
11739:Fluoxetine
11712:LY-215,840
11700:amesergide
11686:Dotarizine
11666:Cinanserin
11656:Captodiame
11642:sertindole
11634:quetiapine
11626:olanzapine
11567:WAY-161503
11551:tryptamine
11547:psilocybin
11491:PNU-181731
11450:lophophine
11436:Oxaflozane
11394:Lorcaserin
11389:Flumexadol
11351:ergotamine
11232:5-MeO-DiPT
11048:Ritanserin
11013:Metadoxine
10998:Ketanserin
10972:amesergide
10944:quetiapine
10936:olanzapine
10878:tryptamine
10874:psilocybin
10778:Lorcaserin
10760:ergotamine
10615:Xylamidine
10584:setoperone
10516:aptazapine
10503:Temanogrel
10474:nefazodone
10466:lubazodone
10434:Ritanserin
10399:Pelanserin
10339:Ketanserin
10334:Irindalone
10319:Fananserin
10297:LY-215,840
10289:amesergide
10275:Dotarizine
10260:Cinanserin
10237:sertindole
10229:quetiapine
10221:olanzapine
10205:lurasidone
10157:amperozide
10121:Altanserin
10101:5-I-R91150
10084:tryptamine
10080:psilocybin
10001:lophophine
9982:PNU-181731
9967:Oxaflozane
9935:Lorcaserin
9930:Jimscaline
9920:Flumexadol
9878:ergotamine
9746:5-MeO-DiPT
9567:eletriptan
9548:Lasmiditan
9522:CP-122,288
9440:tryptamine
9430:eletriptan
9330:Ritanserin
9290:Ketanserin
9265:BRL-15,572
9193:eletriptan
9185:avitriptan
9162:PNU-142633
9157:PNU-109291
9123:ergotamine
9092:CP-122,288
9001:Isamoltane
8975:tertatolol
8967:penbutolol
8963:oxprenolol
8959:isamoltane
8951:alprenolol
8942:AR-A000002
8885:eletriptan
8877:avitriptan
8840:ergotamine
8813:CP-122,288
8798:CGS-12066A
8751:Carvedilol
8730:Xylamidine
8725:WAY-100635
8720:WAY-100135
8690:SB-649,915
8680:Robalzotan
8645:Isamoltane
8615:Dotarizine
8599:tertatolol
8583:penbutolol
8579:oxprenolol
8575:isamoltane
8559:alprenolol
8544:sertindole
8511:Xaliproden
8506:Vilazodone
8496:U-92,016-A
8485:psilocybin
8473:indorenate
8444:Sunepitron
8439:SSR-181507
8389:Piclozotan
8379:Oxaflozane
8374:Osemozotan
8339:Lesopitron
8329:Flumexadol
8319:Flesinoxan
8263:ergotamine
8202:Bay R 1531
8184:eptapirone
8176:Azapirones
8166:quetiapine
8162:lurasidone
8128:vilazodone
8116:nefazodone
8051:modulators
7971:Toreforant
7961:Seliforant
7925:-Histidine
7860:Pitolisant
7840:Irdabisant
7825:GSK-189254
7805:Ciproxifan
7800:Burimamide
7744:Methimepip
7739:-Histidine
7659:Tuvatidine
7649:Sufotidine
7644:Roxatidine
7639:Ranitidine
7624:Pibutidine
7619:Oxmetidine
7609:Nizatidine
7589:Lupitidine
7574:Lafutidine
7564:Famotidine
7559:Etintidine
7554:Ebrotidine
7549:Donetidine
7539:Cimetidine
7534:Burimamide
7508:-Histidine
7433:Tagorizine
7423:GSK1004723
7413:Elbanizine
7408:Belarizine
7334:imipramine
7262:nefazodone
7233:quetiapine
7225:olanzapine
7182:Vapitadine
7152:Rupatadine
7132:Pibaxizine
7087:Loratadine
7047:Epinastine
7042:Emedastine
7007:Clemastine
7002:Cetirizine
6992:Cabastinen
6977:Bepiastine
6972:Barmastine
6962:Azelastine
6957:Astemizole
6952:Alinastine
6882:Pipoxizine
6732:Doxylamine
6697:Deptropine
6687:Dacemazine
6657:Clemastine
6637:Chlorothen
6617:Captodiame
6577:Antazoline
6543:-Histidine
6494:modulators
6419:Clemastine
6324:Epinastine
6248:Rupatadine
6243:Loratadine
6228:Deptropine
6194:Tricyclics
6149:Antazoline
6009:Cetirizine
5963:Doxylamine
5943:Clemastine
5897:Emedastine
5887:Azelastine
5882:Astemizole
5782:(4): 558.
5641:10 January
5199:14 January
4043:J Clin Med
3746:1 December
3502:(6): 963.
3247:Prescriber
2890:J Pain Res
2500:(1): 279.
1902:References
1886:SARS-CoV-2
1834:adipocytes
1804:azelastine
1800:astemizole
1789:Conditions
1783:metabolite
1755:microsomes
1712:Litigation
1706:Alcon Inc.
1489:mast cells
1351:pitolisant
1284:leukopenia
1217:dysarthria
1157:nosebleeds
1145:drowsiness
1104:absorption
999:mast cells
995:angioedema
925:ophthalmic
897:porphyrias
838:mast cells
708:3D model (
696:Molar mass
599:ChEMBL1633
515:HBD503WORO
507:X49220T18G
470:ChemSpider
422:IUPHAR/BPS
378:34580-14-8
370:34580-13-7
361:CAS Number
340:IUPAC name
307:Metabolism
21:Ketoprofen
14854:Tipindole
14834:Pizotifen
14799:Perlapine
14794:Oxetorone
14784:Monatepil
14749:Cidoxepin
14734:Beloxepin
14729:Atiprosin
14719:Adosopine
14660:Etazepine
14542:Promazine
14517:Pinoxepin
14452:Metoxepin
14442:Metiapine
14427:Maroxepin
14367:Erizepine
14347:Clozapine
14332:Clomacran
14282:Asenapine
14277:Amoxapine
14184:Ketotifen
14124:Bisulepin
14119:Azatadine
14081:Tandamine
14046:Opipramol
13961:Losindole
13941:Iprindole
13916:Hepzidine
13836:Cidoxepin
13801:Amoxapine
13781:Amezepine
13776:Amoxapine
13568:See also:
13534:pergolide
13526:Ergolines
13452:mianserin
13444:amoxapine
13430:Spiperone
13415:SB-691673
13405:SB-656104
13400:SB-269970
13395:SB-258741
13390:SB-258719
13311:Ergolines
13262:clozapine
13250:asenapine
13221:N-Me-5-HT
13217:bufotenin
13185:Sarizotan
13180:RU-24,969
13155:Ergolines
13135:8-OH-DPAT
13132:Agonists:
13092:pergolide
13076:Ergolines
13023:mianserin
13019:amoxapine
13010:SB-742457
13005:SB-399885
13000:SB-357134
12995:SB-271046
12990:SB-258585
12970:PRX-07034
12930:GW-742457
12915:BVT-74316
12905:BGC20-760
12863:clozapine
12855:asenapine
12807:N-Me-5-HT
12803:LY-586713
12783:Bufotenin
12767:2-Me-5-HT
12715:Ergolines
12712:Agonists:
12664:Ergolines
12654:SB-699551
12634:Asenapine
12585:Ergolines
12582:Agonists:
12553:SB-204070
12548:SB-203186
12533:Piboserod
12523:GR-125487
12518:GR-113808
12502:Zacopride
12487:Tegaserod
12477:RS-67,506
12472:RS-67,333
12462:PRX-03140
12452:Mosapride
12437:Dazopride
12432:CJ-033466
12427:Cisapride
12417:Capeserod
12404:Agonists:
12344:Zacopride
12286:mianserin
12282:amoxapine
12243:Memantine
12213:Dazopride
12198:Bupropion
12183:Azasetron
12169:clozapine
12145:Alosetron
12111:halothane
12093:2-Me-5-HT
12084:SR-57227A
12063:quipazine
12020:Agonists:
11960:Ergolines
11955:Efavirenz
11894:Trazodone
11874:mianserin
11858:amoxapine
11839:SB-243213
11834:SB-242084
11829:SB-228357
11824:SB-221284
11819:SB-206553
11814:SB-200646
11804:RS-102221
11789:Pizotifen
11759:Ketotifen
11744:FR-260010
11696:Ergolines
11622:melperone
11610:clozapine
11602:asenapine
11523:bufotenin
11501:Ro60-0213
11496:Ro60-0175
11486:PNU-22394
11476:quipazine
11454:mescaline
11441:PHA-57378
11431:ORG-37684
11426:ORG-12962
11383:pergolide
11331:Ergolines
11304:Dimemebfe
11299:CP-809101
11294:Alstonine
11289:AL-38022A
11270:α-Me-5-HT
11266:5-MeO-αMT
11262:5-MeO-αET
11240:5-MeO-DPT
11236:5-MeO-DMT
11228:5-MeO-DET
11191:Agonists:
11157:Ergolines
11141:Yohimbine
11121:Trazodone
11111:mianserin
11107:amoxapine
11098:Tegaserod
11088:SB-228357
11083:SB-221284
11078:SB-215505
11073:SB-206553
11068:SB-204741
11063:SB-200646
11053:RS-127445
11038:PRX-08066
11028:Pizotifen
11003:LY-393558
10988:LY-272015
10968:Ergolines
10963:EGIS-7625
10924:clozapine
10912:asenapine
10850:bufotenin
10846:α-Me-5-HT
10820:Ro60-0175
10815:PNU-22394
10772:pergolide
10744:Ergolines
10717:BW-723C86
10674:Agonists:
10636:Ergolines
10620:Yohimbine
10592:spiramide
10588:spiperone
10528:mianserin
10512:amoxapine
10488:SR-46349B
10482:trazodone
10419:Pizotifen
10384:Nantenine
10354:LY-393558
10285:Ergolines
10209:melperone
10189:clozapine
10165:asenapine
10142:perlapine
10138:ketotifen
10056:bufotenin
10019:quipazine
10005:mescaline
9977:PNU-22394
9972:PHA-57378
9925:IHCH-7113
9914:pergolide
9850:Ergolines
9845:Efavirenz
9813:Dimemebfe
9803:AL-37350A
9784:α-Me-5-HT
9780:5-MeO-αMT
9776:5-MeO-αET
9754:5-MeO-DPT
9750:5-MeO-DMT
9742:5-MeO-DET
9688:25CN-NBOH
9676:25C-NBOMe
9672:25B-NBOMe
9668:25I-NBOMe
9652:Agonists:
9607:Mianserin
9553:LY-334370
9527:Ergolines
9517:BRL-54443
9514:Agonists:
9473:Ergolines
9411:Ergolines
9406:BRL-54443
9403:Agonists:
9373:pergolide
9361:Ergolines
9335:Yohimbine
9325:Mianserin
9315:LY-456220
9310:LY-456219
9305:LY-393558
9300:LY-367642
9295:LY-310762
9285:GR-127935
9275:Ergolines
9270:Elzasonan
9260:Alniditan
9107:Ergolines
9102:CP-286601
9097:CP-135807
9089:Agonists:
9047:Ergolines
9031:Yohimbine
9026:SB-236057
9021:SB-224289
9016:SB-216641
9006:LY-393558
8996:GR-127935
8986:Ergolines
8981:Elzasonan
8955:carteolol
8863:RU-24,969
8852:pergolide
8828:Ergolines
8818:CP-135807
8790:Agonists:
8756:Ergolines
8705:Spiramide
8700:Spiperone
8650:Lecozotan
8630:FCE-24379
8620:Ergolines
8605:BMY-7,378
8587:pindobind
8563:carteolol
8516:Yohimbine
8477:N-Me-5-HT
8465:bufotenin
8457:5-MeO-DMT
8429:Sarizotan
8409:RU-24,969
8404:Roxindole
8399:Repinotan
8364:Naluzotan
8349:LY-301317
8344:LY-293284
8283:pergolide
8247:Ergolines
8232:Ebalzotan
8222:Dimemebfe
8212:BMY-14802
8207:Befiradol
8180:buspirone
8158:clozapine
8146:asenapine
8120:trazodone
8089:8-OH-DPAT
8086:Agonists:
7956:Mianserin
7917:Histamine
7865:SCH-79687
7820:Enerisant
7815:Conessine
7716:Histamine
7669:Xaltidine
7654:Tiotidine
7614:Osutidine
7594:Metiamide
7579:Lamtidine
7490:Histamine
7475:Amthamine
7443:Trenizine
7338:iprindole
7292:mianserin
7280:amoxapine
7266:trazodone
7217:clozapine
7205:asenapine
7187:Zepastine
7167:Talastine
7157:Setastine
7147:Rocastine
7127:Perastine
7117:Octastine
7107:Moxastine
7062:Ketotifen
7027:Dorastine
7012:Clemizole
6987:Bilastine
6902:Talastine
6877:Piperoxan
6852:Perlapine
6842:Oxatomide
6832:Moxastine
6797:Meclozine
6737:Embramine
6677:Cyclizine
6612:Buclizine
6602:Bromazine
6582:Azatadine
6530:Histamine
6378:trazodone
6344:Perlapine
6238:Ketotifen
6218:Azatadine
6051:Oxatomide
6046:Meclizine
6031:Cyclizine
6004:Buclizine
5952:+naproxen
5907:Talastine
5892:Bilastine
5399:237216445
5219:Drugs.com
4840:263801715
4737:211246051
4694:236998913
3296:NBK501527
3277:Ketotifen
3012:Molecules
2121:242916740
1850:serotonin
1818:pizotifen
1684:Economics
1641:pizotifen
1625:azatadine
1617:tricyclic
1571:tricyclic
1567:pizotifen
1497:basophils
1485:cytokines
1392:histamine
1381:selective
1347:donepezil
1343:bupropion
1272:hepatitis
1213:nystagmus
1209:myoclonus
1153:dry mouth
1113:tear duct
814:itchiness
794:Ketotifen
591:ChEMBL534
321:half-life
177:eye drops
166:Routes of
140:Pregnancy
129:Ketotifen
88:Monograph
82:Drugs.com
30:Ketotifen
14886:Medicine
14824:Pirolate
14617:Zotepine
14502:Perazine
14417:Loxapine
13996:Mezepine
13981:Mazindol
13966:Loxapine
13951:Litracen
13689:Acridine
13530:lisuride
13504:pimozide
13500:loxapine
13339:LY-53857
13290:zotepine
13195:Triptans
13059:loxapine
12910:BVT-5182
12753:Hypidone
12731:lisuride
12543:RS-67532
12538:RS-39604
12528:L-Lysine
12365:LY-53857
12315:loxapine
12208:CSP-2503
12129:YM-31636
12079:SR-57227
12069:RS-56812
12023:Alcohols
11925:pimozide
11921:loxapine
11889:Tramadol
11708:LY-53857
11650:zotepine
11543:psilocin
11359:LA-SS-Az
11355:lisuride
11284:A-372159
11258:5-Fl-αMT
11254:5-Cl-αMT
10984:LY-53857
10980:lisuride
10870:psilocin
10695:cloforex
10682:Aminorex
10572:pimozide
10564:loxapine
10493:TGBA01AD
10293:LY-53857
10265:CSP-2503
10249:zotepine
10111:AC-90179
10076:psilocin
9886:LA-SS-Az
9882:lisuride
9798:AL-34662
9772:5-Fl-αMT
9768:5-Cl-αMT
9728:2C-B-FLY
9664:25I-NBOH
9660:25I-NBMD
9563:Triptans
9535:lysergol
9481:lysergol
9426:Triptans
9369:lysergol
9365:lisuride
9231:5-Et-DMT
9177:Triptans
9172:TGBA01AD
9147:L-772405
9142:L-694247
9137:GR-46611
9059:lisuride
8873:Triptans
8808:CP-94253
8803:CP-93129
8640:GR-46611
8610:CSP-2503
8591:pindolol
8501:Urapidil
8491:TGBA01AD
8481:psilocin
8414:S-14,506
8334:Hypidone
8314:F-15,599
8289:F-11,461
8267:lisuride
8227:Dopamine
8188:gepirone
7992:See also
7976:VUF-6002
7935:VUF-8430
7900:Agonists
7875:VUF-5681
7790:Bavisant
7770:A-423579
7765:A-349821
7749:Proxyfan
7699:Agonists
7485:Dimaprit
7480:Betazole
7468:Agonists
7403:Azanator
7376:loxapine
7284:loxapine
7245:zotepine
7032:Ebastine
6587:Bamipine
6513:Agonists
6404:Bamipine
6106:Bamipine
5968:Ebastine
5808:33810356
5746:Archived
5742:18889707
5734:20650926
5692:26755686
5635:Archived
5623:20623616
5581:24409414
5527:13 April
5521:Archived
5501:13 April
5495:Archived
5475:13 April
5469:Archived
5449:13 April
5443:Archived
5423:13 April
5417:Archived
5391:34410005
5334:Archived
5308:Archived
5282:Archived
5256:Archived
5223:Archived
5193:Archived
5189:ClinCalc
5169:10 March
5163:Archived
5139:10 March
5133:Archived
5109:10 March
5103:Archived
5079:13 April
5073:Archived
5026:13 April
5020:Archived
4990:Archived
4986:Drugbank
4966:1 August
4960:Archived
4919:Archived
4832:37815801
4793:24659435
4729:32086998
4686:34387278
4651:31463682
4602:73482611
4594:30779379
4559:34335590
4462:Archived
4433:Archived
4392:17357376
4357:: 1–12.
4332:11764306
4291:45012360
4283:23713715
4215:12515585
4161:23525348
4075:31470575
4024:35538735
3928:25370135
3850:36891173
3740:Archived
3720:11 March
3714:Archived
3627:11 March
3618:Archived
3592:11 March
3583:Archived
3520:Archived
3516:23279031
3391:25839342
3341:2 August
3335:Archived
3300:Archived
3286:30000587
3197:Archived
3171:Archived
3115:17307970
3093:Circ Res
3044:33918481
2993:31135881
2922:31118754
2868:72293850
2825:14973969
2774:13 April
2768:Archived
2748:13 April
2739:Archived
2706:Archived
2681:13 April
2672:Archived
2670:. 2022.
2643:Archived
2561:25944644
2526:34238222
2475:23282889
2386:24267353
2317:14587946
2309:19772513
2269:36816214
2215:30634949
2207:23902458
2172:36000122
2067:Archived
2063:DailyMed
2034:10 March
2028:Archived
2004:10 March
1998:Archived
1972:10 March
1966:Archived
1931:Archived
1927:DailyMed
1895:in-vitro
1880:COVID-19
1858:caffeine
1830:cytokine
1748:In vitro
1733:Research
1661:Novartis
1399:receptor
1276:jaundice
1193:sedation
1183:Overdose
1126:swelling
1081:epilepsy
1012:flushing
901:epilepsy
828:such as
784:(verify)
442:DrugBank
326:12 hours
185:ATC code
173:By mouth
155: B1
142:category
124:DailyMed
14462:Naranol
13896:Doxepin
13681:Classes
13542:(e.g.,
13528:(e.g.,
13482:(e.g.,
13464:(e.g.,
13442:(e.g.,
13425:SLV-314
13420:SLV-313
13313:(e.g.,
13301:DR-4485
13240:(e.g.,
13207:(e.g.,
13197:(e.g.,
13157:(e.g.,
13150:E-55888
13100:(e.g.,
13078:(e.g.,
13053:(e.g.,
13041:doxepin
13031:(e.g.,
13017:(e.g.,
12900:AVN-397
12895:AVN-322
12890:AVN-211
12885:AVN-101
12849:(e.g.,
12842:ABT-354
12811:ST-1936
12765:(e.g.,
12717:(e.g.,
12680:(e.g.,
12666:(e.g.,
12610:(e.g.,
12587:(e.g.,
12372:(e.g.,
12323:(e.g.,
12313:(e.g.,
12296:Thujone
12280:(e.g.,
12167:(e.g.,
12160:AS-8112
12119:toluene
12109:(e.g.,
12091:(e.g.,
12053:(e.g.,
12027:butanol
12025:(e.g.,
11962:(e.g.,
11915:(e.g.,
11901:(e.g.,
11884:TIK-301
11856:(e.g.,
11809:S-14671
11698:(e.g.,
11600:(e.g.,
11562:WAY-629
11513:(e.g.,
11462:(e.g.,
11448:(e.g.,
11401:(e.g.,
11371:LSD-Pip
11333:(e.g.,
11311:(e.g.,
11252:(e.g.,
11218:2C-T-21
11196:(e.g.,
11159:(e.g.,
11136:TIK-301
11128:(e.g.,
11105:(e.g.,
10970:(e.g.,
10902:(e.g.,
10832:(e.g.,
10807:(e.g.,
10785:(e.g.,
10746:(e.g.,
10724:(e.g.,
10689:(e.g.,
10638:(e.g.,
10550:(e.g.,
10540:(e.g.,
10510:(e.g.,
10456:(e.g.,
10444:S-14671
10344:KML-010
10287:(e.g.,
10155:(e.g.,
10128:(e.g.,
10046:(e.g.,
10013:(e.g.,
9999:(e.g.,
9942:(e.g.,
9898:LSD-Pip
9852:(e.g.,
9825:(e.g.,
9766:(e.g.,
9733:2CB-Ind
9722:2C-T-21
9700:(e.g.,
9656:25I-NBF
9583:(e.g.,
9565:(e.g.,
9529:(e.g.,
9475:(e.g.,
9438:(e.g.,
9428:(e.g.,
9413:(e.g.,
9363:(e.g.,
9277:(e.g.,
9221:(e.g.,
9179:(e.g.,
9109:(e.g.,
9049:(e.g.,
8988:(e.g.,
8949:(e.g.,
8906:(e.g.,
8875:(e.g.,
8830:(e.g.,
8758:(e.g.,
8685:S-15535
8675:NAN-190
8622:(e.g.,
8557:(e.g.,
8534:(e.g.,
8451:(e.g.,
8424:S-15535
8419:S-14671
8359:MKC-242
8309:F-15063
8304:F-14679
8299:F-13714
8294:F-12826
8249:(e.g.,
8178:(e.g.,
8140:(e.g.,
8106:(e.g.,
7785:AZD5213
7780:ABT-652
7775:ABT-239
7726:Immepip
7513:UR-AK49
7362:(e.g.,
7330:doxepin
7308:(e.g.,
7278:(e.g.,
7256:(e.g.,
7199:(e.g.,
7194:Others:
6548:UR-AK49
6434:Doxepin
6395:topical
6376:(e.g.,
6310:doxepin
6308:(e.g.,
6303:Others:
6210:(e.g.,
6098:Others:
5799:8065848
5776:Viruses
5683:4819856
5631:8888404
5572:3885374
5340:8 April
5288:2 April
5262:2 April
5069:6806019
4878:9759694
4785:9951950
4642:7007452
4550:8322976
4508:1377628
4152:3605515
4110:8737746
4066:6780525
3919:4417653
3841:9987324
3792:9165365
3696:7335554
3669:6123414
3526:3 April
3447:6113023
3438:1505736
3383:1418695
3074:1702263
3035:8038309
2913:6500880
2860:1600111
2816:8406918
2649:17 July
2608:6806019
2569:5723622
2517:8265096
2466:3488932
2377:4309375
2289:Allergy
2260:9922628
2163:9391663
2113:2226222
1779:prodrug
1651:History
1487:, from
1390:of the
1169:opioids
1165:alcohol
1138:itching
934:in its
923:in its
666:Formula
487:4445563
451:DB00920
411:5282408
389:PubChem
270:Rx-only
266: /
237::
205: (
203:S01GX08
201:)
195: (
193:R06AX17
126::
102:a604033
14872:Portal
14712:Others
13767:(TCAs)
13175:LP-211
12965:MS-245
12791:E-6837
12787:E-6801
12041:m-CPBG
11572:YM-348
11421:MK-212
11335:ALD-52
11214:2C-T-7
11210:2C-T-2
10039:TFMFly
9962:O-4310
9858:ALD-52
9854:1P-LSD
9818:DMBMPP
9718:2C-T-7
9714:2C-T-2
8715:UH-301
8655:Mefway
7930:OUP-16
7721:Imetit
6363:Others
5806:
5796:
5740:
5732:
5690:
5680:
5629:
5621:
5579:
5569:
5397:
5389:
5067:
4952:
4911:
4876:
4838:
4830:
4791:
4783:
4735:
4727:
4692:
4684:
4649:
4639:
4600:
4592:
4557:
4547:
4506:
4425:
4390:
4330:
4289:
4281:
4244:
4213:
4206:140320
4203:
4159:
4149:
4135:: 27.
4108:
4073:
4063:
4022:
3982:
3953:
3926:
3916:
3875:
3848:
3838:
3790:
3694:
3667:
3514:
3445:
3435:
3389:
3381:
3293:
3284:
3113:
3072:
3042:
3032:
2991:
2954:
2920:
2910:
2866:
2858:
2823:
2813:
2606:
2567:
2559:
2524:
2514:
2473:
2463:
2384:
2374:
2315:
2307:
2267:
2257:
2213:
2205:
2170:
2160:
2140:Cureus
2119:
2111:
1838:leptin
1535:CYP3A4
1499:, and
1483:, and
1437:) and
1349:, and
1290:, and
1280:anemia
1254:, and
1205:tremor
1201:ataxia
940:asthma
871:, and
848:) and
846:eczema
810:asthma
796:is an
734:SMILES
701:309.43
582:ChEMBL
543:D01332
535:D08105
268:
262:
249:
239:℞-only
122:
13170:LP-44
13165:LP-12
13140:AS-19
12412:BIMU8
12333:xenon
11480:TFMPP
10809:TFMPP
10034:TCB-2
10023:TFMPP
9987:RH-34
8899:TFMPP
8550:AV965
8369:NBUMP
5749:(PDF)
5738:S2CID
5710:(PDF)
5627:S2CID
5395:S2CID
5049:Chest
4836:S2CID
4789:S2CID
4765:Drugs
4733:S2CID
4690:S2CID
4598:S2CID
4465:(PDF)
4458:(PDF)
4287:S2CID
4189:: 2.
3649:Chest
3621:(PDF)
3614:(PDF)
3586:(PDF)
3579:(PDF)
3387:S2CID
2864:S2CID
2742:(PDF)
2731:(PDF)
2675:(PDF)
2668:(PDF)
2588:Chest
2565:S2CID
2313:S2CID
2211:S2CID
2117:S2CID
2093:Drugs
1826:TNF-α
1771:TNF-α
1752:liver
1175:, or
1134:hives
915:with
754:InChI
710:JSmol
554:ChEBI
312:Liver
14809:P7C3
13609:and
13213:5-MT
13209:5-CT
13117:5-HT
12799:EMDT
12779:5-MT
12775:5-CT
12771:5-BT
12697:5-HT
12612:5-CT
12567:5-HT
12407:5-MT
12389:5-HT
12097:5-CT
12059:mCPP
12005:5-HT
11987:5-HT
11661:CEPC
11531:DiPT
11519:5-CT
11515:5-BT
11472:mCPP
11415:MMDA
11411:MDOH
11399:MDxx
11244:5-MT
11206:2C-I
11202:2C-E
11198:2C-B
11176:5-HT
11008:mCPP
10858:DiPT
10842:5-MT
10838:5-CT
10834:5-BT
10799:MMDA
10795:MDOH
10783:MDxx
10659:5-HT
10359:mCPP
10148:AMDA
10064:DiPT
10052:5-CT
10048:5-BT
9956:MMDA
9952:MDOH
9940:MDxx
9758:5-MT
9710:2C-I
9706:2C-E
9702:2C-B
9637:5-HT
9625:5-HT
9585:5-MT
9499:5-HT
9388:5-HT
9235:5-MT
9227:5-CT
9223:5-BT
9152:mCPP
9074:5-HT
8916:5-MT
8912:5-CT
8908:5-BT
8858:mCPP
8775:5-HT
8670:MPPF
8461:5-MT
8453:5-CT
8354:mCPP
8071:5-HT
8059:5-HT
7495:HTMT
6535:HTMT
6393:For
5804:PMID
5757:2019
5730:PMID
5688:PMID
5643:2024
5619:PMID
5577:PMID
5529:2024
5503:2024
5477:2024
5451:2024
5425:2024
5387:PMID
5342:2024
5316:2020
5290:2024
5264:2024
5231:2020
5201:2024
5171:2024
5141:2024
5111:2024
5081:2024
5065:PMID
5028:2024
4998:2023
4968:2020
4950:ISBN
4927:2024
4909:ISBN
4874:PMID
4828:PMID
4781:PMID
4725:PMID
4682:PMID
4647:PMID
4590:PMID
4555:PMID
4504:PMID
4473:2024
4441:2024
4423:ISBN
4388:PMID
4328:PMID
4279:PMID
4242:ISBN
4211:PMID
4157:PMID
4106:PMID
4071:PMID
4020:PMID
3980:ISBN
3951:ISBN
3924:PMID
3873:ISBN
3846:PMID
3788:PMID
3748:2023
3722:2024
3692:PMID
3665:PMID
3629:2024
3594:2024
3551:1447
3528:2024
3512:PMID
3443:PMID
3379:PMID
3343:2017
3308:2023
3290:NCBI
3282:PMID
3205:2023
3179:2023
3111:PMID
3070:PMID
3040:PMID
2989:PMID
2952:ISBN
2918:PMID
2856:PMID
2821:PMID
2799:2004
2776:2024
2750:2024
2714:2023
2683:2024
2651:2024
2604:PMID
2557:PMID
2522:PMID
2471:PMID
2382:PMID
2305:PMID
2265:PMID
2203:PMID
2168:PMID
2109:PMID
2036:2024
2006:2024
1974:2024
1939:2020
1757:and
1635:and
1602:and
1569:, a
1541:and
1447:5-HT
1431:mACh
1330:and
1300:coma
1274:and
1266:and
1059:and
1053:cGMP
1051:and
1049:cAMP
985:and
936:oral
913:salt
832:and
526:KEGG
498:UNII
479:3695
431:7206
403:3827
281:data
78:AHFS
65:USAN
13159:LSD
12735:LSD
12597:LSD
12055:BZP
11539:DPT
11535:DMT
11527:DET
11468:BZP
11379:LSP
11375:LSH
11367:LSD
11363:LSB
11325:DOM
11321:DOI
11317:DOC
11313:DOB
11309:DOx
11278:αMT
11274:αET
11194:2Cs
10866:DPT
10862:DMT
10854:DET
10738:DOM
10734:DOI
10730:DOC
10726:DOB
10722:DOx
10072:DPT
10068:DMT
10060:DET
10015:BZP
9906:LSP
9902:LSH
9894:LSD
9890:LSB
9839:DOM
9835:DOI
9831:DOC
9827:DOB
9823:DOx
9792:αMT
9788:αET
9698:2Cs
9243:DMT
9127:LSD
8920:DMT
8469:DMT
8271:LSD
6397:use
5858:R06
5794:PMC
5784:doi
5722:doi
5714:Gut
5678:PMC
5670:doi
5611:doi
5567:PMC
5559:doi
5379:doi
5251:MSN
5057:doi
4901:doi
4866:doi
4862:158
4820:doi
4773:doi
4717:doi
4674:doi
4637:PMC
4629:doi
4582:doi
4545:PMC
4535:doi
4496:doi
4492:211
4415:doi
4359:doi
4318:doi
4271:doi
4234:doi
4201:PMC
4191:doi
4147:PMC
4137:doi
4098:doi
4061:PMC
4051:doi
4012:doi
3914:PMC
3906:doi
3836:PMC
3826:doi
3778:doi
3657:doi
3555:doi
3504:doi
3473:doi
3433:PMC
3425:doi
3421:282
3371:doi
3255:doi
3228:doi
3142:doi
3101:doi
3097:100
3030:PMC
3020:doi
2981:doi
2944:doi
2908:PMC
2898:doi
2848:doi
2811:PMC
2803:doi
2635:doi
2596:doi
2549:doi
2512:PMC
2502:doi
2461:PMC
2451:doi
2413:doi
2372:PMC
2364:doi
2360:111
2297:doi
2255:PMC
2245:doi
2195:doi
2158:PMC
2148:doi
2101:doi
2024:emc
1860:or
1692:000
1690:400
1010:of
899:or
615:EPA
393:CID
301:75%
291:60%
264:OTC
251:POM
208:WHO
198:WHO
14898::
13532:,
13502:,
13498:,
13494:,
13490:,
13486:,
13472:,
13468:,
13454:,
13450:,
13446:,
13357:,
13353:,
13349:,
13345:,
13341:,
13337:,
13333:,
13329:,
13325:,
13321:,
13317:,
13288:,
13284:,
13280:,
13276:,
13272:,
13268:,
13264:,
13260:,
13256:,
13252:,
13248:,
13244:,
13219:,
13215:,
13211:,
13090:,
13086:,
13082:,
13057:,
13043:,
13039:,
13035:,
13021:,
12877:,
12873:,
12869:,
12865:,
12861:,
12857:,
12853:,
12813:,
12809:,
12805:,
12801:,
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12793:,
12789:,
12785:,
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12777:,
12773:,
12769:,
12745:,
12741:,
12737:,
12733:,
12729:,
12725:,
12721:,
12670:,
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12331:,
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12288:,
12284:,
12175:,
12171:,
12121:,
12117:,
12113:,
12099:,
12095:,
12061:,
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12033:,
12029:,
11966:,
11931:,
11927:,
11923:,
11919:,
11905:,
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11868:,
11864:,
11860:,
11726:,
11722:,
11718:,
11714:,
11710:,
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11640:,
11636:,
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11628:,
11624:,
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11612:,
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11533:,
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11113:,
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