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Ketamine

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1351:, found that when compared with placebo, people treated with either ketamine or esketamine experienced reduction or remission of symptoms lasting 1 to 7 days. There were 18.7% (4.1 to 40.4%) more people reporting some benefit and 9.6% (0.2 to 39.4%) more who achieved remission within 24 hours of ketamine treatment. Among people receiving esketamine, 2.1% (2.5 to 24.4%) more encountered some relief at 24 hours and 10.3% (4.5 to 18.2%) more had few or no symptoms. These effects did not persist beyond one week, although higher dropout rate in some studies mean that the duration of benefit remains unclear. 47: 855: 832: 1532:
symptoms of psychosis such as going into a hole, disappearing, feeling as if melting, experiencing colors, and hallucinations are described by 6–10% of people. Dizziness, blurred vision, dry mouth, hypertension, nausea, increased or decreased body temperature, or feeling flushed are the common (>10%) non-psychiatric side effects. All these adverse effects are most pronounced by the end of the injection, dramatically reduced 40 minutes afterward, and completely disappear within 4 hours after the injection.
1480: 2880: 2865: 2745: 2847: 3003:(PCP) as an anesthetic. The researchers wanted to call the state of ketamine anesthesia "dreaming", but Parke-Davis did not approve of the name. Hearing about this problem and about the "disconnected" appearance of treated people, Mrs. Edward F. Domino, the wife of one of the pharmacologists working on ketamine, suggested "dissociative anesthesia". Following FDA approval in 1970, ketamine anesthesia was first given to American soldiers during the 38: 38846: 1276:(CRPS). However, the 2018 consensus guidelines on chronic pain concluded that, overall, there is only weak evidence in favor of ketamine use in spinal injury pain, moderate evidence in favor of ketamine for CRPS, and weak or no evidence for ketamine in mixed neuropathic pain, fibromyalgia, and cancer pain. In particular, only for CRPS there is evidence of medium to longer term pain relief. 4457:"The Canadian Network for Mood and Anxiety Treatments (CANMAT) Task Force Recommendations for the Use of Racemic Ketamine in Adults with Major Depressive Disorder: Recommandations Du Groupe De Travail Du Réseau Canadien Pour Les Traitements De L'humeur Et De L'anxiété (Canmat) Concernant L'utilisation De La Kétamine Racémique Chez Les Adultes Souffrant De Trouble Dépressif Majeur" 9468: 2971:
receiving the drug therapeutically (during general anesthesia), 1–2 mg/L in those arrested for impaired driving and 3–20 mg/L in victims of acute fatal overdosage. Urine is often the preferred specimen for routine drug use monitoring purposes. The presence of norketamine, a pharmacologically active metabolite, is useful for confirmation of ketamine ingestion.
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are only a few pilot studies studying the optimal dose, increasing evidence suggests that 0.5 mg/kg dose injected over 40 minutes gives an optimal outcome. The antidepressant effect of ketamine is diminished at 7 days, and most people relapse within 10 days, although for a significant minority the improvement may last 30 days or more.
1381:(NDEs) when the widest possible definition of an NDE is used. Ketamine can reproduce features that commonly have been associated with NDEs. A 2019 large-scale study found that written reports of ketamine experiences had a high degree of similarity to written reports of NDEs in comparison to other written reports of drug experiences. 2700:(0.29–0.84 μM). At similar plasma concentrations (70 to 160 ng/mL; 0.29–0.67 μM) it also shows analgesic effects. In 1–5 minutes after inducing anesthesia by a rapid intravenous injection of ketamine, its plasma concentration reaches as high as 60–110 μM. When the anesthesia was maintained using 2970:
Ketamine may be quantitated in blood or plasma to confirm a diagnosis of poisoning in hospitalized people, provide evidence in an impaired driving arrest, or to assist in a medicolegal death investigation. Blood or plasma ketamine concentrations are usually in a range of 0.5–5.0 mg/L in persons
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may result in improved mood within 4 hours reaching the peak at 24 hours. A single dose of intravenous ketamine has been shown to result in a response rate greater than 60% as early as 4.5 hours after the dose (with a sustained effect after 24 hours) and greater than 40% after 7 days. Although there
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together with continuous injection of ketamine, the ketamine concentration stabilized at approximately 9.3 μM. In an experiment with purely ketamine anesthesia, people began to awaken once the plasma level of ketamine decreased to about 2,600 ng/mL (11 μM) and became oriented in place and
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and dissociative effects. When used recreationally, it is found both in crystalline powder and liquid form, and is often referred to by users as "Special K" or simply "K". The long-term effects of repeated use are largely unknown, and are an area of active investigation. Liver and urinary toxicity
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The discovery of antidepressive action of ketamine in 2000 has been described as the single most important advance in the treatment of depression in more than 50 years. It has sparked interest in NMDA receptor antagonists for depression, and has shifted the direction of antidepressant research and
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Liver toxicity of ketamine involves higher doses and repeated administration. In a group of chronic high dose ketamine users, the frequency of liver injury was reported to be about 10%. There are case reports of increased liver enzymes involving ketamine treatment of chronic pain. Chronic ketamine
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and, possibly, ketamine intestinal metabolism by CYP3A4. As a result, norketamine plasma levels are several-fold higher than ketamine following oral administration, and norketamine may play a role in anesthetic and analgesic action of oral ketamine. This also explains why oral ketamine levels are
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bioavailability is 77%. Subcutaneous bioavailability has never been measured, but is presumed to be high. Among the less invasive routes, the intranasal route has the highest bioavailability (45–50%) and oral – the lowest (16–20%). Sublingual and rectal bioavailabilities are intermediate at
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The mechanism of action of ketamine in alleviating depression is not well understood, and is an area of active investigation. Because of the hypothesis that NMDA receptor antagonism underlies the antidepressant effects of ketamine, esketamine was developed as an antidepressant. However, multiple
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effects are reported in people treated with ketamine at plasma concentrations of approximately 100 to 250 ng/mL (0.42–1.1 μM). The typical intravenous antidepressant dosage of ketamine used to treat depression is low and results in maximal plasma concentrations of 70 to 200 ng/mL
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At lower sub-anesthetic doses, psychiatric side effects are prominent. Most people feel strange, spacey, woozy, or a sense of floating, or have visual distortions or numbness. Also very frequent (20–50%) are difficulty speaking, confusion, euphoria, drowsiness, and difficulty concentrating. The
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is different from that of other anesthetics. It suppresses breathing much less than most other available anesthetics. When used at anesthetic doses, ketamine usually stimulates rather than depresses the circulatory system. Protective airway reflexes are preserved and it is sometimes possible to
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Ketamine is especially useful in the pre-hospital setting, due to its effectiveness and low risk of respiratory depression. Ketamine has similar efficacy to opioids in a hospital emergency department setting for management of acute pain and for control of procedural pain. It may also prevent
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One of the main challenges with ketamine treatment can be the length of time that the antidepressant effects lasts after finishing a course of treatment. A possible option may be maintenance therapy with ketamine which usually runs twice a week to once in two weeks. Ketamine may decrease
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Ketamine infusions are used for acute pain treatment in emergency departments and in the perioperative period for individuals with refractory pain. The doses are lower than those used for anesthesia; they are usually referred to as sub-anesthetic doses. Adjunctive to
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binding by ketamine in humans, with some studies finding a significant decrease and others finding no such effect. However, changes in raclopride binding may be due to changes in dopamine concentrations induced by ketamine rather than binding of ketamine to the
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Jordan S, Chen R, Fernalld R, Johnson J, Regardie K, Kambayashi J, et al. (July 2006). "In vitro biochemical evidence that the psychotomimetics phencyclidine, ketamine and dizocilpine (MK-801) are inactive at cloned human and rat dopamine D2 receptors".
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Marcantoni WS, Akoumba BS, Wassef M, Mayrand J, Lai H, Richard-Devantoy S, et al. (December 2020). "A systematic review and meta-analysis of the efficacy of intravenous ketamine infusion for treatment resistant depression: January 2009 – January 2019".
3161:'s October 2023 apparent drowning death was revealed to have been caused by a ketamine overdose, and while other factors were present, the acute effects of ketamine were ruled to be the primary cause of death. Because of its ability to cause confusion and 9561:
Parkin MC, Turfus SC, Smith NW, Halket JM, Braithwaite RA, Elliott SP, Osselton MD, Cowan DA, Kicman AT. Detection of ketamine and its metabolites in urine by ultra high pressure liquid chromatography-tandem mass spectrometry. J. Chrom. B 876: 137–142,
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Krystal JH, Karper LP, Seibyl JP, Freeman GK, Delaney R, Bremner JD, et al. (March 1994). "Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses".
5508:"Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists" 19957: 9551:
Feng N, Vollenweider FX, Minder EI, Rentsch K, Grampp T, Vonderschmitt DJ. Development of a gas chromatography-mass spectrometry method for determination of ketamine in plasma and its application to human samples. Ther. Drug Monit. 17: 95–100,
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Chankvetadze B, Burjanadze N, Breitkreutz J, Bergander K, Bergenthal D, Kataeva O, et al. (2002). "Mechanistic study on the opposite migration order of the enantiomers of ketamine with α- and β-cyclodextrin in capillary electrophoresis".
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or on its own, ketamine reduces morphine use, pain level, nausea, and vomiting after surgery. Ketamine is likely to be most beneficial for surgical patients when severe post-operative pain is expected, and for opioid-tolerant patients.
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Bartova L, Vogl SE, Stamenkovic M, Praschak-Rieder N, Naderi-Heiden A, Kasper S, et al. (November 2015). "Combination of intravenous S-ketamine and oral tranylcypromine in treatment-resistant depression: A report of two cases".
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symptoms, primarily anxiety, shaking, sweating, and palpitations, following the attempts to stop. Cognitive deficits as well as increased dissociation and delusion symptoms were observed in frequent recreational users of ketamine.
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Although the incidence of ketamine dependence is unknown, some people who regularly use ketamine develop ketamine dependence. Animal experiments also confirm the risk of misuse. Additionally, the rapid onset of effects following
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Martial C, Cassol H, Charland-Verville V, Pallavicini C, Sanz C, Zamberlan F, et al. (March 2019). "Neurochemical models of near-death experiences: A large-scale study based on the semantic similarity of written reports".
6166: 9764: 6296: 19897: 1830:, which does not significantly interact with the NMDA receptor but nonetheless indirectly activates AMPA receptors, may also or alternatively be involved in the rapid-onset antidepressant effects of ketamine. In NMDA 10494: 1802:
antagonist activity, may have antidepressant action. This furthers the argument that NMDA receptor antagonism may not be primarily responsible for the antidepressant effects of ketamine. Acute inhibition of the
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Recreational ketamine use has been implicated in deaths globally, with more than 90 deaths in England and Wales in the years of 2005–2013. They include accidental poisonings, drownings, traffic accidents, and
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partial agonist with the potency similar to that of its NMDA receptor antagonism. However, later studies by different researchers found the affinity of ketamine of >10 μM for the regular human and rat
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Handa F, Tanaka M, Nishikawa T, Toyooka H (February 2000). "Effects of oral clonidine premedication on side effects of intravenous ketamine anesthesia: a randomized, double-blind, placebo-controlled study".
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occurs only rarely with ketamine. Ketamine, generally, stimulates breathing; however, in the first 2–3 minutes of a high-dose rapid intravenous injection it may cause a transient respiratory depression.
10621: 1782:, have thus far failed to demonstrate significant effectiveness for depression. Furthermore, animal research indicates that arketamine, the enantiomer with a weaker NMDA receptor antagonism, as well as 26062: 1576:. The wall is thickened and the functional bladder capacity is as low as 10–150 mL. Studies indicate that ketamine-induced cystitis is caused by ketamine and its metabolites directly interacting with 19453: 19159: 10050: 9978: 5109:
Cohen L, Athaide V, Wickham ME, Doyle-Waters MM, Rose NG, Hohl CM (January 2015). "The effect of ketamine on intracranial and cerebral perfusion pressure and health outcomes: a systematic review".
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Ketamine is frequently used in severely injured people and appears to be safe in this group. It has been widely used for emergency surgery in field conditions in war zones, for example, during the
10591: 5020:"Attenuation of ketamine effects by nimodipine pretreatment in recovering ethanol dependent men: psychopharmacologic implications of the interaction of NMDA and L-type calcium channel antagonists" 21247: 7096:
Morgan CJ, Muetzelfeldt L, Curran HV (January 2010). "Consequences of chronic ketamine self-administration upon neurocognitive function and psychological wellbeing: a 1-year longitudinal study".
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Molero P, Ramos-Quiroga JA, Martin-Santos R, Calvo-Sánchez E, Gutiérrez-Rojas L, Meana JJ (May 2018). "Antidepressant Efficacy and Tolerability of Ketamine and Esketamine: A Critical Review".
25210: 25205: 25200: 24528: 23446: 23441: 23436: 11107: 1197:. Ketamine is unlikely to lower blood pressure, which is dangerous for people with severe head injury; in fact, it can raise blood pressure, often making it useful in treating such injuries. 10086: 12631: 8626:
da Costa FL, Pinto MC, Santos DC, Carobin NV, de Jesus IC, Ferreira LA, et al. (December 2020). "Ketamine potentiates TRPV1 receptor signaling in the peripheral nociceptive pathways".
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Clinical observations suggest that benzodiazepines may diminish the antidepressant effects of ketamine. It appears most conventional antidepressants can be safely combined with ketamine.
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Urinary toxicity occurs primarily in people who use large amounts of ketamine routinely, with 20–30% of frequent users having bladder complaints. It includes a range of disorders from
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Castellani D, Pirola GM, Gubbiotti M, Rubilotta E, Gudaru K, Gregori A, et al. (April 2020). "What urologists need to know about ketamine-induced uropathy: A systematic review".
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for clinical use. While S-ketamine is more effective as an analgesic and anesthetic through NMDA receptor antagonism, R-ketamine produces longer-lasting effects as an antidepressant.
6162: 265: 24643: 2803:, with only 2% remaining unchanged. Conjugated hydroxylated derivatives of ketamine (80%) followed by dehydronorketamine (16%) are the most prevalent metabolites detected in urine. 131: 9756: 6292: 5863:
Sanacora G, Frye MA, McDonald W, Mathew SJ, Turner MS, Schatzberg AF, et al. (April 2017). "A Consensus Statement on the Use of Ketamine in the Treatment of Mood Disorders".
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Table from the 2010 ISCD study ranking various drugs (legal and illegal) based on statements by drug-harm experts. Ketamine was found to be the 11th overall most dangerous drug.
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Corssen G, Domino EF (January–February 1966). "Dissociative anesthesia: further pharmacologic studies and first clinical experience with the phencyclidine derivative CI-581".
18942: 23921: 2466: 10490: 26234: 24337: 8380:"Subunit-dependent inhibition of human neuronal nicotinic acetylcholine receptors and other ligand-gated ion channels by dissociative anesthetics ketamine and dizocilpine" 7353:
Peltoniemi MA, Hagelberg NM, Olkkola KT, Saari TI (September 2016). "Ketamine: A Review of Clinical Pharmacokinetics and Pharmacodynamics in Anesthesia and Pain Therapy".
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Peltoniemi MA, Hagelberg NM, Olkkola KT, Saari TI (September 2016). "Ketamine: A Review of Clinical Pharmacokinetics and Pharmacodynamics in Anesthesia and Pain Therapy".
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At anesthetic doses, 10–20% of adults and 1–2% of children experience adverse psychiatric reactions that occur during emergence from anesthesia, ranging from dreams and
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Robson MJ, Elliott M, Seminerio MJ, Matsumoto RR (April 2012). "Evaluation of sigma (σ) receptors in the antidepressant-like effects of ketamine in vitro and in vivo".
2621:. Collectively, these findings shed doubt on the involvement of monoamine reuptake inhibition in the effects of ketamine in humans. Ketamine has been found to increase 23110: 13710: 12598: 11100: 10001: 5244: 2567:
With a couple of exceptions, ketamine actions at other receptors are far weaker than ketamine's antagonism of the NMDA receptor (see the activity table to the right).
1272:. In multiple clinical trials, ketamine infusions delivered short-term pain relief in neuropathic pain diagnoses, pain after traumatic spine injury, fibromyalgia, and 1113: 36841: 36836: 36831: 36826: 36821: 35909: 32256: 27319: 26979: 26049: 24954: 24663: 23105: 19824: 14477: 12624: 18856: 18807: 11879: 10548: 4924:
Wong JJ, Lee JH, Turner DA, Rehder KJ (August 2014). "A review of the use of adjunctive therapies in severe acute asthma exacerbation in critically ill children".
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was banned and destroyed by authorities owing to its inclusion of an essay by Woodard about the entheogenic use of, and psychonautic experiences with, ketamine.
19639: 301: 38956: 31824: 28454: 26160: 25948: 23356: 23165: 21282: 20905: 18881: 13749: 12834: 12342: 11269: 10613: 4974:"Attenuation of the neuropsychiatric effects of ketamine with lamotrigine: support for hyperglutamatergic effects of N-methyl-D-aspartate receptor antagonists" 16368: 8986:
Seeman P, Guan HC, Hirbec H (August 2009). "Dopamine D2High receptors stimulated by phencyclidines, lysergic acid diethylamide, salvinorin A, and modafinil".
35212: 34746: 34741: 34736: 34731: 25034: 13705: 11093: 8182:"NMDA receptor antagonists ketamine and PCP have direct effects on the dopamine D(2) and serotonin 5-HT(2)receptors-implications for models of schizophrenia" 7941:"The ketamine analogue methoxetamine and 3- and 4-methoxy analogues of phencyclidine are high affinity and selective ligands for the glutamate NMDA receptor" 3232:. Ketamine is also used to manage pain among large animals. It is the primary intravenous anesthetic agent used in equine surgery, often in conjunction with 314: 220: 16239: 10029: 9968: 9712:
Berman RM, Cappiello A, Anand A, Oren DA, Heninger GR, Charney DS, et al. (February 2000). "Antidepressant effects of ketamine in depressed patients".
35217: 34711: 23307: 19336: 18689: 18684: 18674: 12617: 12593: 11874: 1826:. It is not clear whether ketamine alone is sufficient for antidepressant action or its metabolites are also important; the active metabolite of ketamine, 35613: 7625:
Yang Y, Cui Y, Sang K, Dong Y, Ni Z, Ma S, et al. (February 2018). "Ketamine blocks bursting in the lateral habenula to rapidly relieve depression".
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Kraus C, Rabl U, Vanicek T, Carlberg L, Popovic A, Spies M, et al. (March 2017). "Administration of ketamine for unipolar and bipolar depression".
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is responsible for the anesthetic, analgesic, and psychotomimetic effects of ketamine. Blocking of the NMDA receptor results in analgesia by preventing
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in pursuit of a safer anesthetic with fewer hallucinogenic effects. It was approved for use in the United States in 1970. It has been regularly used in
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Ketamine has been suggested as a possible therapy for children with severe acute asthma who do not respond to standard treatment. This is due to its
10526: 10076: 9093:"Comparison of the effects of ketamine and memantine on prolactin and cortisol release in men. a randomized, double-blind, placebo-controlled trial" 6114: 3870: 38901: 37072: 35207: 34566: 32251: 29754: 24924: 24397: 20221: 19346: 16249: 15959: 15899: 15804: 15573: 14000: 12959: 11354: 8943:
Seeman P, Guan HC (November 2008). "Phencyclidine and glutamate agonist LY379268 stimulate dopamine D2High receptors: D2 basis for schizophrenia".
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For chronic pain, ketamine is used as an intravenous analgesic, particularly if the pain is neuropathic. It has the added benefit of counteracting
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Hijazi Y, Boulieu R (July 2002). "Contribution of CYP3A4, CYP2B6, and CYP2C9 isoforms to N-demethylation of ketamine in human liver microsomes".
8429:"Ketamine and ketamine metabolites as novel estrogen receptor ligands: Induction of cytochrome P450 and AMPA glutamate receptor gene expression" 35572: 35110: 34643: 34633: 34623: 34471: 34098: 34020: 33239: 33219: 32997: 31804: 28753: 27578: 26351: 26115: 24392: 19663: 18758: 17379: 16124: 16069: 16064: 16029: 15648: 15543: 14904: 14287: 13136: 11289: 11046: 2999:
in 1964. These investigations demonstrated ketamine's short duration of action and reduced behavioral toxicity made it a favorable choice over
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experiences with ketamine. Turner died prematurely due to drowning during presumed unsupervised ketamine use. In 2006, the Russian edition of
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Rao LK, Flaker AM, Friedel CC, Kharasch ED (December 2016). "Role of Cytochrome P4502B6 Polymorphisms in Ketamine Metabolism and Clearance".
2832: 2799:-labelled ketamine, 91% of the radioactivity is recovered from urine and 3% from the feces. The medication is excreted mostly in the form of 77: 4881:
Adams HA (December 1997). "" [S-(+)-ketamine. Circulatory interactions during total intravenous anesthesia and analgesia-sedation].
4302:"Psychedelics, but Not Ketamine, Produce Persistent Antidepressant-like Effects in a Rodent Experimental System for the Study of Depression" 2709:, a proxy for the brain concentration, during anesthesia varied between 2.8 and 6.5 μM and was approximately 40% lower than in plasma. 38543: 36169: 36164: 35282: 34653: 34648: 34638: 34608: 34603: 34551: 34501: 34481: 34476: 34466: 34451: 34446: 34441: 34436: 34410: 34405: 34317: 34239: 34078: 34073: 34063: 34058: 34053: 34043: 34000: 33995: 33985: 33980: 33975: 33965: 32777: 30650: 29901: 27683: 27598: 27024: 26277: 26247: 26198: 25918: 25908: 25009: 25004: 24513: 23227: 22769: 22764: 22045: 22040: 21859: 20575: 20560: 20092: 19962: 19922: 19265: 17559: 16982: 16957: 16872: 16519: 16509: 16099: 16089: 16059: 16054: 16019: 15974: 15919: 15909: 15904: 15190: 15149: 15099: 15044: 14035: 14015: 13832: 13574: 12884: 12194: 12189: 11899: 11884: 11389: 11384: 11329: 11319: 11279: 11159: 7453:"Sub-anesthetic concentrations of (R,S)-ketamine metabolites inhibit acetylcholine-evoked currents in α7 nicotinic acetylcholine receptors" 980: 35272: 1405:
effects. A 2012 Cochrane review found there were minimal adverse effects reported, but the limited studies showed no significant benefit.
37479: 35562: 35426: 34984: 34658: 34546: 34541: 34536: 34531: 34506: 34461: 34400: 34365: 34312: 34307: 34234: 34229: 34166: 33833: 33411: 32937: 28701: 27688: 27613: 27563: 27234: 26969: 26947: 26922: 26912: 26757: 26386: 25858: 25712: 25375: 25190: 24833: 24242: 20932: 20811: 20791: 20786: 20743: 20570: 20540: 20231: 20129: 20102: 20052: 20019: 19999: 19994: 19937: 19932: 19917: 19907: 19887: 19882: 19473: 19433: 19381: 19119: 19054: 19044: 19039: 18442: 17564: 17544: 17529: 17499: 16917: 16827: 16259: 16164: 16154: 16134: 16114: 16094: 14277: 13269: 12709: 12704: 12412: 12184: 11929: 11573: 11462: 11284: 11274: 10129: 9370: 8003:"Stereoselective interaction of ketamine with recombinant mu, kappa, and delta opioid receptors expressed in Chinese hamster ovary cells" 3281: 9538: 8530:"Antidepressants modulate the in vitro inhibitory effects of propofol and ketamine on norepinephrine and serotonin transporter function" 6140: 4867: 3578: 3513: 1701:
reduces the increase of salivation, heart-rate and blood-pressure during ketamine anesthesia and decreases the incidence of nightmares.
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Stevens CL, Klundt IL, Munk ME, Pillai MD (1965). "Amino ketone rearrangements. IV. Thermal rearrangements of α-amino methyl ketones".
5766:"Efficacy and safety of prophylactic use of ketamine for prevention of postanesthetic shivering: a systematic review and meta analysis" 37459: 37449: 37444: 37429: 37424: 37419: 37399: 37394: 37389: 37384: 37369: 37354: 37344: 37334: 37329: 37319: 37299: 37274: 37239: 37026: 37016: 37006: 36986: 36981: 36971: 36961: 36931: 36926: 34151: 34141: 34136: 34131: 33878: 33873: 33868: 33863: 33853: 33848: 33843: 33838: 33828: 33818: 33808: 33788: 33778: 33773: 33768: 33583: 29652: 27523: 27518: 27513: 27508: 27289: 27102: 26872: 26333: 26302: 26203: 26090: 25943: 25923: 25813: 25793: 25520: 24843: 23841: 23471: 23145: 22886: 21277: 21272: 20607: 20602: 20597: 20592: 20124: 19544: 19019: 16967: 16947: 16343: 16323: 14537: 13979: 13925: 13116: 13059: 13024: 12999: 12904: 12729: 12724: 12089: 11656: 11314: 11294: 6163:"FDA approves new nasal spray medication for treatment-resistant depression; available only at a certified doctor's office or clinic" 3440:
Moyse DW, Kaye AD, Diaz JH, Qadri MY, Lindsay D, Pyati S (March 2017). "Perioperative Ketamine Administration for Thoracotomy Pain".
10410: 4509:"Next-Step Treatment Considerations for Patients With Treatment-Resistant Depression That Responds to Low-Dose Intravenous Ketamine" 3220:, and other small animals. It is frequently used in induction and anesthetic maintenance in horses. It is an important part of the " 290: 38971: 36896: 36891: 36881: 36861: 34968: 33942: 33748: 33743: 33693: 33244: 32423: 27538: 27533: 27528: 27419: 27414: 27294: 26999: 26897: 26892: 26877: 26812: 26807: 26554: 25525: 25089: 24878: 23978: 23300: 23270: 18260: 17582: 17231: 16328: 15760: 15668: 13141: 11419: 11184: 10316: 9905: 9224:"Plasma levels of ketamine and two of its metabolites in surgical patients using a gas chromatographic mass fragmentographic assay" 9135:
Rabiner EA (May 2007). "Imaging of striatal dopamine release elicited with NMDA antagonists: is there anything there to be seen?".
8320:"Interaction of intravenous anesthetics with recombinant human M1-M3 muscarinic receptors expressed in chinese hamster ovary cells" 6732: 9386:"CYP2B6*6 allele and age substantially reduce steady-state ketamine clearance in chronic pain patients: impact on adverse effects" 8232:"Effects of Ketamine and Ketamine Metabolites on Evoked Striatal Dopamine Release, Dopamine Receptors, and Monoamine Transporters" 8042:
Hirota K, Sikand KS, Lambert DG (1999). "Interaction of ketamine with mu2 opioid receptors in SH-SY5Y human neuroblastoma cells".
3415: 3329: 3096: 1073:. Its distinguishing features as anesthesia are preserved breathing and airway reflexes, stimulated heart function with increased 35744: 33713: 33603: 33593: 33588: 33285: 33002: 32542: 32221: 31794: 29696: 27503: 26994: 26483: 26013: 25938: 25933: 25868: 19214: 18498: 16451: 15724: 13414: 12229: 10038: 5315:
Hemmingsen C, Nielsen JE (November 1991). "Intravenous ketamine for prevention of severe hypotension during spinal anaesthesia".
1336:). The Canadian Network for Mood and Anxiety Treatments (CANMAT) recommends esketamine as a third-line treatment for depression. 10146:
Giannini AJ, Underwood NA, Condon M (November 2000). "Acute ketamine intoxication treated by haloperidol: a preliminary study".
6079:"Ketamine for suicidal ideation in adults with psychiatric disorders: A systematic review and meta-analysis of treatment trials" 34843: 34838: 34833: 34828: 34818: 33232: 32902: 32433: 27488: 27483: 24237: 21267: 20925: 20107: 19942: 19356: 19189: 19124: 16348: 16274: 15742: 15733: 14075: 14070: 12064: 11766: 11339: 11174: 10556: 9690: 2626: 2613:, which is of importance as the combination of a monoamine reuptake inhibitor with an MAOI can produce severe toxicity such as 7504: 4784: 38485: 35557: 32912: 32231: 31774: 30707: 29596: 28148: 19989: 18793: 17283: 13735: 10922: 10377: 10350: 10328: 10297: 10274: 10239: 10198: 10113:"Schedules of Controlled Substances: Placement of Ketamine into Schedule III [21 CFR Part 1308. Final Rule 99-17803]" 9839: 9364: 9039: 6327: 3800: 3572: 3507: 3275: 9860: 5252: 2664:, subanesthetic doses of ketamine have not been found to do this in humans and in fact, have been found to dose-dependently 34904: 33536: 32511: 31426: 28204: 17723: 17701: 15797: 9686: 6925: 5815:
Elia N, Tramèr MR (January 2005). "Ketamine and postoperative pain—a quantitative systematic review of randomised trials".
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3675:"Rapid-acting antidepressant ketamine, its metabolites and other candidates: A historical overview and future perspective" 1393:
that has not responded to standard treatments, but only case studies and no randomized controlled trials support its use.
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Dayton PG, Stiller RL, Cook DR, Perel JM (1983). "The binding of ketamine to plasma proteins: emphasis on human plasma".
10560: 9462:, Stevens, Calvin L., "Aminoketones and methods for their production", issued 31 May 1966, assigned to 326: 38941: 38926: 37622: 35828: 32952: 32326: 31607: 30784: 29802: 26476: 21620: 20826: 19653: 18525: 15830: 11868: 11864: 11127: 10440: 7231:"Potentiation of low dose ketamine effects by naltrexone: potential implications for the pharmacotherapy of alcoholism" 2705:
time when the level was down to 1,000 ng/mL (4 μM). In a single-case study, the concentration of ketamine in
1224: 6748:"Comprehensive assessment of side effects associated with a single dose of ketamine in treatment-resistant depression" 4257:
Zhang K, Hashimoto K (January 2019). "An update on ketamine and its two enantiomers as rapid-acting antidepressants".
1129:
The use of ketamine in anesthesia reflects its characteristics. It is a drug of choice for short-term procedures when
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Rosati A, De Masi S, Guerrini R (November 2018). "Ketamine for Refractory Status Epilepticus: A Systematic Review".
3247:
Ketamine appears not to produce sedation or anesthesia in snails. Instead, it appears to have an excitatory effect.
2549:, the former showing approximately 3- to 4-fold greater affinity for the receptor than the latter. As a result, the 1025: 114: 34914: 34889: 34874: 32942: 32847: 32762: 32707: 32516: 32348: 32336: 30724: 29613: 28165: 25655: 23069: 16795: 12640: 6193:"Ketamine and other glutamate receptor modulators for depression in adults with unipolar major depressive disorder" 2190: 2154: 1200:
Ketamine is an option in children as the sole anesthetic for minor procedures or as an induction agent followed by
5604:
Svenson J, Biedermann M (2011). "Ketamine: a unique drug with several potential uses in the prehospital setting".
3177:
Ketamine is under investigation for its potential in treating treatment-resistant depression. Ketamine is a known
1811:
and referred to as the "anti-reward center", is another possible mechanism for ketamine's antidepressant effects.
38921: 38204: 34899: 33506: 33181: 33105: 33007: 32702: 32666: 32501: 32408: 31769: 26579: 25650: 17486: 17306: 15790: 15133: 14164: 12466: 6055: 3065: 3020: 2955: 2943: 2911:-ketamine), is also available for medical use under the brand name Ketanest S, while the less active enantiomer, 921: 571: 250: 95: 10741:
Ferreira SR, Machado AR, Furtado LF, Gomes JH, de Almeida RM, de Oliveira Mendes T, et al. (October 2020).
7727:"Glutamatergic Signaling Drives Ketamine-Mediated Response in Depression: Evidence from Dynamic Causal Modeling" 38931: 36656: 33227: 32982: 32967: 32947: 32922: 32907: 32867: 32807: 32757: 32393: 26619: 25575: 23274: 19811: 15769: 13074: 12670: 12009: 11918: 11487: 10956: 6492: 5066:
Barrett W, Buxhoeveden M, Dhillon S (October 2020). "Ketamine: a versatile tool for anesthesia and analgesia".
1879: 1660:
rapidly develops, even with repeated medical use, prompting the use of higher doses. Some daily users reported
1584:
of the bladder lining and increased permeability of the urothelial barrier which results in clinical symptoms.
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Huang, MC., Lin, SK. (2020). "Ketamine Abuse: Past and Present". In: Hashimoto, K., Ide, S., Ikeda, K. (eds.)
3157:. The majority of deaths were among young people. Several months after being found dead in his hot tub, actor 672: 38891: 38876: 38667: 36651: 35641: 35312: 34994: 33161: 33110: 32882: 32877: 32872: 32797: 32792: 32787: 32727: 32438: 31283: 29645: 22330: 19559: 18897: 18053: 17783: 12004: 11451: 2583: 2530: 1928: 1867: 1863: 1747: 38961: 38911: 33426: 32987: 32977: 32932: 32917: 32897: 32887: 32862: 32842: 32772: 32732: 32722: 32712: 29068: 28711: 27752: 27713: 24773: 23250: 20967: 20948: 20891: 18852: 15715: 13700: 12588: 10472:
A report of the Mortality team, Life Events and Population Sources Division, Office for National Statistics
9438: 7133:"Additive interactions between propofol and ketamine when used for anesthesia induction in female patients" 2996: 2823:
cyclopentylmagnesium bromide to give (2-chlorophenyl)(cyclopentyl)methanone. This is then brominated using
1835: 1587:
Management of ketamine-induced cystitis involves ketamine cessation as the first step. This is followed by
1436: 1362: 850: 723: 8676:
Tyler MW, Yourish HB, Ionescu DF, Haggarty SJ (June 2017). "Classics in Chemical Neuroscience: Ketamine".
6641:
Nutt DJ, King LA, Phillips LD (November 2010). "Drug harms in the UK: a multicriteria decision analysis".
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3105:, characterised by a sense of detachment from one's physical body and the external world that is known as 38966: 38896: 38646: 37999: 36749: 35354: 33421: 33278: 33083: 33019: 32962: 32837: 32832: 32827: 32812: 32802: 32752: 32747: 32737: 32717: 32697: 32656: 32107: 30307: 30240: 27404: 26343: 22614: 21890: 20186: 18832: 12764: 10518: 6343:
Peinkhofer C, Dreier JP, Kondziella D (July 2019). "Semiology and Mechanisms of Near-Death Experiences".
6293:"FDA alerts health care professionals of potential risks associated with compounded ketamine nasal spray" 6078: 4455:
Swainson J, McGirr A, Blier P, Brietzke E, Richard-Devantoy S, Ravindran N, et al. (November 2020).
2734: 2606: 1344: 1250: 811: 6746:
Acevedo-Diaz EE, Cavanaugh GW, Greenstein D, Kraus C, Kadriu B, Zarate CA, et al. (February 2020).
3840: 3528: 1854:
and mediate antidepressant effects. Such downstream actions of the activation of AMPA receptors include
38936: 38836: 35796: 35719: 33556: 33526: 33191: 33166: 32892: 32852: 32822: 32767: 31181: 30070: 29978: 28731: 25753: 25748: 25140: 24483: 23571: 21609: 21121: 19979: 15038: 14139: 13088: 12814: 12684: 12318: 12258: 9944: 2408: 2350: 1871: 1799: 1783: 1604: 9459: 3060:, in response to rising recreational use and the use of ketamine as a date rape drug, has added it to 1523:. Vomiting can be expected in 5–15% of the patients; pretreatment with propofol mitigates it as well. 800: 520: 38705: 38478: 36526: 36060: 35929: 35838: 33196: 32443: 32177: 32122: 31255: 30866: 30082: 27349: 27057: 25773: 24763: 24488: 23806: 18818: 18392: 17715: 17613: 17297: 16809: 12019: 11989: 11437: 10884:
Stunkard JA, Miller JC (September 1974). "An outline guide to general anesthesia in exotic species".
9886:"Statutes of Canada (S.C.) Controlled Drugs and Substances Act (S.C. 1996 c.19) Schedule I § 14" 9476: 6491:
Gomes D, Pimentel J, Bentes C, Aguiar de Sousa D, Antunes AP, Alvarez A, et al. (October 2018).
4746: 3609:
Marland S, Ellerton J, Andolfatto G, Strapazzon G, Thomassen O, Brandner B, et al. (June 2013).
3102: 3083: 3082:
The increase in recreational use prompted ketamine to be placed in Schedule III of the United States
2840: 1808: 1628: 1348: 1325: 387: 381: 205: 9897: 6655: 5631:
Karlow N, Schlaepfer CH, Stoll CR, Doering M, Carpenter CR, Colditz GA, et al. (October 2018).
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Woodall AJ, McCrohan CR (December 2000). "Excitatory actions of propofol and ketamine in the snail
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Mion G (September 2017). "History of anaesthesia: The ketamine story – past, present and future".
4215:"Clinical practice guideline for emergency department ketamine dissociative sedation: 2011 update" 38951: 38554: 37087: 37041: 36800: 32496: 32463: 32453: 32403: 32398: 32023: 31342: 31337: 30712: 29601: 29317: 28721: 28377: 28153: 27788: 26323: 25738: 24362: 24144: 23087: 20841: 18666: 18602: 17938: 15844: 14557: 12804: 11786: 11641: 10686:"mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists" 10046: 8087:"Role of kappa-opioid receptors in the effects of salvinorin A and ketamine on attention in rats" 6245:"Ketamine and other glutamate receptor modulators for depression in adults with bipolar disorder" 2377: 1814:
Possible biochemical mechanisms of ketamine's antidepressant action include direct action on the
1649: 1340: 1213: 375: 369: 180: 59: 32486: 10042: 9757:"Yale Researchers Study Potential Treatment for Depression in Patients With Parkinson's Disease" 6010:"Ketamine treatment for depression: opportunities for clinical innovation and ethical foresight" 5506:
Schwenk ES, Viscusi ER, Buvanendran A, Hurley RW, Wasan AD, Narouze S, et al. (July 2018).
38115: 36791: 36006: 35924: 35724: 35651: 35404: 35364: 35336: 33323: 33271: 32577: 32013: 32008: 31744: 31545: 31349: 31278: 30777: 30547: 30018: 29365: 28321: 27558: 27359: 27067: 26609: 25150: 24164: 24139: 24038: 23266: 23262: 22669: 21945: 21375: 21328: 20716: 20191: 19984: 19796: 19787: 18470: 18406: 17797: 16763: 16754: 16318: 16305: 16287: 16229: 15853: 14943: 14119: 13093: 11856: 11588: 11085: 11073: 10112: 7451:
Moaddel R, Abdrakhmanova G, Kozak J, Jozwiak K, Toll L, Jimenez L, et al. (January 2013).
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Due to the bronchodilating properties of ketamine it can be used for anesthesia in people with
1209: 409: 35242: 35237: 31905: 12609: 10743:"Ketamine can be produced by Pochonia chlamydosporia: an old molecule and a new anthelmintic?" 10320: 9829: 9354: 9091:
Hergovich N, Singer E, Agneter E, Eichler HG, Graselli U, Simhandl C, et al. (May 2001).
3265: 2717:
Ketamine can be absorbed by many different routes due to both its water and lipid solubility.
87: 38023: 35990: 35919: 35520: 35399: 35302: 35165: 32458: 32413: 32373: 31829: 31071: 30907: 30793: 30753: 29988: 29124: 28818: 28736: 28726: 28438: 28381: 26964: 25305: 23601: 22387: 22319: 21793: 21095: 20711: 18434: 18335: 15289: 14563: 14230: 13659: 13608: 13569: 12547: 12496: 12432: 12209: 12154: 11604: 11583: 11429: 10266: 10262: 10258: 9029: 7311:"Ketamine for Depression, 5: Potential Pharmacokinetic and Pharmacodynamic Drug Interactions" 6136: 4847: 4649:
Cohen SP, Bhatia A, Buvanendran A, Schwenk ES, Wasan AD, Hurley RW, et al. (July 2018).
3562: 3497: 3209: 2900: 2725:
is 100% by definition, intramuscular injection bioavailability is slightly lower at 93%, and
2622: 2571: 1743: 1573: 1569: 1378: 1201: 932: 780: 663: 393: 10912: 10434:
See Max Daly, 2014, "The Sad Demise of Nancy Lee, One of Britain's Ketamine Casualties," at
9479:, Stevens, Calvin L., "Procédé de production d'aminocétones", issued 1963-07-15. 8427:
Ho MF, Correia C, Ingle JN, Kaddurah-Daouk R, Wang L, Kaufmann SH, et al. (June 2018).
7880:
Morris PJ, Moaddel R, Zanos P, Moore CE, Gould TD, Zarate CA, et al. (September 2017).
7229:
Krystal JH, Madonick S, Perry E, Gueorguieva R, Brush L, Wray Y, et al. (August 2006).
6243:
Dean RL, Marquardt T, Hurducas C, Spyridi S, Barnes A, Smith R, et al. (October 2021).
1093:
have been reported among regular users of high doses of ketamine for recreational purposes.
1008:
InChI=1S/C13H16ClNO/c1-15-13(9-5-4-8-12(13)16)10-6-2-3-7-11(10)14/h2-3,6-7,15H,4-5,8-9H2,1H3
38906: 38604: 38471: 38142: 37905: 36871: 36776: 35085: 33186: 33078: 32491: 32448: 32388: 32316: 32289: 31809: 31784: 31754: 31749: 31575: 31376: 30667: 30582: 29335: 29296: 29129: 29119: 29114: 28941: 28746: 28662: 28304: 26787: 23381: 23361: 23258: 23130: 22659: 22203: 21935: 21365: 21344: 20956: 19834: 19549: 19290: 18866: 18028: 16559: 16494: 16474: 15538: 14749: 14020: 13654: 13519: 13499: 13339: 13284: 13199: 12989: 12542: 12462: 12059: 10697: 9893: 7952: 7634: 4159:
Zanos P, Moaddel R, Morris PJ, Riggs LM, Highland JN, Georgiou P, et al. (July 2018).
3068:
requiring a special license for sale and maintenance of records of all sales for two years.
3031: 2816: 2598: 2437: 1600: 1440: 1261: 732: 500: 38506: 38193: 25118: 24461: 23327: 8085:
Nemeth CL, Paine TA, Rittiner JE, Béguin C, Carroll FI, Roth BL, et al. (June 2010).
2835:, with hydrolysis of the tertiary bromine atom. This final intermediate is then heated in 2018: 1986: 1957: 1652:
may increase potential use as a recreational drug. The short duration of effects promotes
712: 627: 601: 8: 38866: 38579: 38105: 37657: 36043: 35954: 34869: 33451: 33156: 33093: 32661: 32597: 32331: 32033: 31955: 31402: 31386: 31332: 31216: 30493: 30433: 29084: 28716: 28545: 28446: 28385: 28272: 28261: 28190: 28058: 27775: 26446: 26032: 25878: 25838: 25165: 24984: 24964: 24262: 24224: 24179: 22944: 22789: 22654: 22382: 22239: 22065: 21930: 21585: 21360: 20196: 19602: 19029: 18927: 18679: 16817: 16221: 15678: 14411: 14050: 13853: 13669: 13554: 13539: 13474: 13069: 12557: 12219: 12104: 11914: 11716: 10394: 10081: 9069: 8479:
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6949:"Changes to the bladder epithelial barrier are associated with ketamine-induced cystitis" 6077:
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3162: 3057: 2896: 2706: 2618: 1834:, acute blockade of NMDA receptors in the brain results in an increase in the release of 1831: 1636: 1205: 1189:, including during physically painful procedures. It is the drug of choice for people in 1105: 1101: 592: 399: 363: 31852: 20763: 10818: 10793: 10701: 10491:"Deaths Related to Drug Poisoning in England and Wales – Office for National Statistics" 9921: 8481:"Ketamine inhibits monoamine transporters expressed in human embryonic kidney 293 cells" 7956: 7638: 7182:"Hypnotic and anesthetic interactions between ketamine and midazolam in female patients" 6704: 4117: 4082: 2625:
in the brain, but instead of being due to dopamine reuptake inhibition, this may be via
1085:. As with many antidepressants, the results of a single administration wane with time. 854: 831: 38946: 38754: 38176: 37587: 35703: 35567: 35155: 33446: 33361: 33100: 32687: 32306: 32162: 32117: 32097: 32056: 31174: 31042: 30994: 30844: 29684: 29680: 29522: 29089: 28987: 28658: 28516: 28450: 27622: 26649: 26623: 26502: 25978: 25285: 24974: 24708: 24598: 24252: 23932: 23716: 23556: 23516: 23319: 23029: 21055: 20139: 20134: 19974: 19818: 18900: 17089: 17084: 16987: 16694: 16464: 13761: 13589: 13529: 13439: 13364: 13259: 13244: 13234: 12643: 12290: 12285: 12044: 11999: 11821: 11472: 11447: 11264: 11141: 11119: 11076: 10831: 10769: 10742: 10718: 10685: 10231: 10221: 10190: 10108: 10006: 9973: 9916: 9811: 9786:
Dhir A (January 2017). "Investigational drugs for treating major depressive disorder".
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pressure (however these remain controversial, with recent studies suggesting otherwise)
1390: 1355: 1186: 1138: 1134: 1130: 465: 460: 201: 142: 25763: 24919: 24159: 11021: 9725: 9109: 9092: 8230:
Can A, Zanos P, Moaddel R, Kang HJ, Dossou KS, Wainer IW, et al. (October 2016).
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Domino EF, Zsigmond EK, Domino LE, Domino KE, Kothary SP, Domino SE (February 1982).
9204: 9152: 9114: 9073: 9035: 9003: 8972: 8960: 8917: 8870: 8832: 8775: 8770: 8753: 8734: 8693: 8655: 8643: 8608: 8559: 8502: 8497: 8480: 8458: 8401: 8396: 8379: 8341: 8336: 8319: 8300: 8261: 8203: 8151: 8116: 8059: 8024: 8019: 8002: 7980: 7911: 7882:"Synthesis and N-Methyl-d-aspartate (NMDA) Receptor Activity of Ketamine Metabolites" 7854: 7809: 7795: 7756: 7707: 7650: 7607: 7566: 7482: 7430: 7370: 7332: 7288: 7252: 7203: 7198: 7181: 7154: 7149: 7132: 7113: 7109: 7078: 7029: 6978: 6909: 6904: 6872: 6860: 6818: 6777: 6724: 6668: 6623: 6561: 6514: 6473: 6414: 6372: 6360: 6323: 6274: 6222: 6110: 6098: 6039: 5987: 5930: 5880: 5876: 5832: 5797: 5746: 5705: 5654: 5578: 5557:"The use of subdissociative-dose ketamine for acute pain in the emergency department" 5537: 5483: 5432: 5381: 5332: 5297: 5217: 5182: 5126: 5095: 5083: 5041: 4995: 4941: 4898: 4859: 4816: 4728: 4680: 4612: 4565: 4538: 4486: 4434: 4422: 4371: 4367: 4335: 4323: 4274: 4236: 4190: 4161:"Ketamine and Ketamine Metabolite Pharmacology: Insights into Therapeutic Mechanisms" 4134: 4122: 4104: 4046: 4007: 3957: 3914: 3910: 3862: 3806: 3796: 3742: 3704: 3640: 3568: 3503: 3449: 3407: 3271: 3106: 2980: 2788: 2757: 2467: 1847: 1843: 1377:
Most people who were able to remember their dreams during ketamine anesthesia report
1178: 1047: 13178: 13174: 13102: 11067: 10835: 9815: 9741: 9682: 9614: 9384:
Li Y, Jackson KA, Slon B, Hardy JR, Franco M, William L, et al. (August 2015).
9257: 9164: 9015: 8929: 8913: 8882: 8514: 8413: 8353: 8163: 8147: 7215: 7166: 6947:
Qixin D, Tianpeng W, Xiaochun Y, Lingqi L, Jiantao Y, Zhongjie L (20 January 2017).
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neurons; in other words, ketamine's actions interfere with pain transmission in the
1081:. At lower, sub-anesthetic doses, it is a promising agent for treatment of pain and 46: 38916: 38772: 38614: 38402: 38072: 37911: 36686: 36326: 35552: 35349: 35045: 33302: 33088: 32671: 32587: 32368: 32311: 32299: 31998: 31877: 31819: 31779: 31736: 31637: 31540: 31501: 31484: 31422: 31319: 30657: 30600: 30536: 30383: 29383: 28857: 27191: 27157: 26654: 26634: 26510: 26168: 26105: 25928: 25644: 25570: 25295: 25024: 24778: 24618: 24332: 23591: 23125: 22980: 22352: 21748: 21445: 21385: 21202: 21116: 20276: 19593: 19539: 19317: 19255: 18932: 18516: 18013: 17928: 17728: 17447: 17236: 16574: 15588: 15456: 15064: 14879: 14488: 14321: 13930: 13769: 13549: 13359: 13254: 13126: 12689: 12665: 12280: 12099: 12054: 11555: 11058: 11017: 10858: 10813: 10805: 10764: 10754: 10713: 10705: 10656: 10254: 10227: 10155: 10120: 9795: 9721: 9651: 9641: 9594: 9534: 9447: 9405: 9397: 9325: 9284: 9235: 9194: 9144: 9104: 9065: 8995: 8952: 8909: 8862: 8822: 8814: 8787: 8765: 8724: 8685: 8635: 8598: 8594: 8590: 8549: 8541: 8492: 8448: 8440: 8391: 8331: 8292: 8251: 8243: 8193: 8143: 8106: 8098: 8071: 8051: 8014: 7970: 7960: 7901: 7893: 7844: 7836: 7799: 7791: 7746: 7738: 7697: 7689: 7662: 7642: 7597: 7556: 7548: 7500: 7472: 7464: 7420: 7412: 7401:"The development of glutamate-based antidepressants is taking longer than expected" 7382: 7362: 7322: 7280: 7242: 7193: 7144: 7105: 7068: 7064: 7060: 7019: 7009: 6968: 6960: 6899: 6852: 6808: 6767: 6759: 6716: 6680: 6660: 6613: 6609: 6605: 6553: 6504: 6463: 6453: 6404: 6396: 6352: 6264: 6260: 6256: 6212: 6208: 6204: 6090: 6029: 6021: 5977: 5969: 5922: 5872: 5824: 5787: 5777: 5736: 5695: 5685: 5644: 5613: 5568: 5527: 5519: 5473: 5463: 5422: 5412: 5371: 5344: 5324: 5287: 5209: 5172: 5162: 5118: 5075: 5031: 4985: 4933: 4890: 4754: 4718: 4670: 4662: 4624: 4604: 4528: 4520: 4476: 4468: 4414: 4363: 4313: 4266: 4226: 4180: 4172: 4112: 4094: 4038: 3999: 3949: 3906: 3852: 3788: 3734: 3694: 3686: 3630: 3622: 3397: 3393: 3389: 3356: 2931: 2927: 2920: 2820: 2546: 2057: 1804: 1414: 1304: 867: 348: 233: 10849:
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While ketamine is marketed legally in many countries worldwide, it is also a
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occurs resulting in a ring-expansion, and the formation of racemic ketamine.
2701: 2654: 2637: 2593:) of the human monoamine transporters has been observed with ketamine or its 2545:
of ketamine bind to the dizocilpine site of the NMDA receptor with different
2526: 1851: 1739: 1620: 1097: 1055: 967: 843: 31890: 26468: 21197: 21192: 10709: 8754:"Multiple mechanisms of ketamine blockade of N-methyl-D-aspartate receptors" 8247: 3897:
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At anesthetic doses, ketamine induces a state of dissociative anesthesia, a
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administer ketamine anesthesia without protective measures to the airways.
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Selective serotonin reuptake inhibitors and serotonin receptor modulators:
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3746: 2995:. After promising preclinical research in animals, ketamine was tested in 38671: 38628: 38600: 38525: 38412: 38364: 38354: 38339: 38334: 38324: 38289: 38229: 38224: 38214: 38057: 38015: 37974: 37934: 37919: 37717: 37687: 37682: 37577: 37572: 37567: 36743: 36706: 36701: 36681: 36646: 36561: 36546: 36541: 36536: 36531: 36506: 36496: 36437: 36432: 36417: 36392: 36341: 36331: 36288: 36272: 36235: 36113: 36076: 35749: 35582: 35307: 35014: 34511: 34420: 33461: 32481: 32428: 32274: 32112: 31980: 31935: 31857: 31834: 31567: 31525: 31233: 31096: 31022: 30977: 30824: 30571: 30468: 30333: 30268: 30263: 30253: 30210: 30195: 30180: 30170: 30140: 30130: 30003: 29973: 29968: 29914: 29891: 29886: 29858: 29815: 29792: 29782: 29724: 29630: 29547: 29527: 29436: 29345: 29276: 29268: 29229: 29154: 29104: 29099: 28998: 28934: 28862: 28706: 28691: 28682: 28616: 28601: 28596: 28586: 28581: 28576: 28526: 28506: 28501: 28496: 28465: 28460: 28416: 28401: 28370: 28349: 28327: 28022: 28017: 27989: 27926: 27918: 27903: 27856: 27698: 27678: 27668: 27633: 27593: 27493: 27424: 27389: 27384: 27374: 27206: 27142: 27097: 27092: 26927: 26887: 26802: 26792: 26767: 26684: 26639: 26604: 26361: 26338: 26252: 26178: 26145: 26125: 26003: 25988: 25983: 25973: 25963: 25883: 25853: 25848: 25693: 25665: 25660: 25630: 25615: 25605: 25585: 25580: 25540: 25505: 25495: 25450: 25430: 25415: 25410: 25380: 25325: 25320: 25315: 25260: 25235: 25220: 25195: 25185: 25175: 25170: 25084: 25079: 25074: 25059: 24999: 24994: 24969: 24828: 24818: 24798: 24758: 24753: 24728: 24713: 24678: 24673: 24573: 24548: 24442: 24437: 24427: 24417: 24407: 24342: 24272: 24229: 24073: 24003: 23973: 23958: 23943: 23916: 23881: 23866: 23851: 23836: 23801: 23791: 23761: 23746: 23721: 23686: 23681: 23671: 23661: 23621: 23616: 23576: 23566: 23501: 23486: 23461: 23421: 23406: 23396: 23185: 23175: 23120: 23091: 23041: 22985: 22938: 22920: 22855: 22835: 22784: 22774: 22749: 22709: 22704: 22649: 22619: 22598: 22588: 22578: 22538: 22477: 22457: 22447: 22427: 22407: 22367: 22357: 22304: 22233: 22215: 22187: 22172: 22131: 22111: 22060: 22050: 22025: 21985: 21980: 21925: 21895: 21874: 21864: 21849: 21814: 21778: 21743: 21672: 21662: 21652: 21647: 21595: 21575: 21565: 21540: 21520: 21450: 21425: 21400: 21395: 21390: 21355: 21350: 21308: 21303: 21252: 21060: 20836: 20821: 20801: 20771: 20701: 20585: 20565: 20555: 20550: 20530: 20491: 20441: 20436: 20421: 20411: 20376: 20326: 20296: 20291: 20281: 20201: 20144: 20097: 20029: 20004: 19952: 19867: 19753: 19691: 19668: 19376: 19361: 19307: 19295: 19109: 19084: 18972: 18947: 18424: 18378: 18255: 18250: 18245: 18170: 18155: 18150: 18105: 18084: 18076: 17988: 17983: 17968: 17953: 17888: 17833: 17409: 17399: 17394: 17389: 17369: 17354: 17344: 17324: 17226: 17209: 17199: 17189: 17179: 17174: 17144: 17119: 17114: 17094: 17079: 17044: 17029: 16992: 16927: 16887: 16877: 16734: 16729: 16714: 16699: 16639: 16504: 16408: 16403: 16398: 16388: 16383: 16264: 16211: 16206: 16191: 16034: 16009: 15999: 15989: 15979: 15969: 15884: 15879: 15869: 15782: 15628: 15613: 15598: 15461: 15431: 15426: 15421: 15391: 15365: 15360: 15355: 15330: 15325: 15310: 15300: 15280: 15275: 15260: 15250: 15245: 15235: 15215: 15200: 15180: 15165: 15119: 15054: 15029: 15019: 15014: 15009: 14964: 14939: 14909: 14859: 14819: 14764: 14759: 14739: 14704: 14689: 14679: 14669: 14649: 14639: 14583: 14498: 14421: 14416: 14401: 14354: 14261: 14256: 14246: 14211: 14186: 14155: 14115: 13995: 13940: 13914: 13904: 13843: 13684: 13649: 13629: 13544: 13534: 13489: 13469: 13389: 13319: 13309: 13299: 13294: 13264: 13054: 13049: 13039: 13029: 12974: 12939: 12929: 12924: 12919: 12909: 12849: 12824: 12819: 12739: 12572: 12537: 12517: 12444: 12422: 12417: 12402: 12362: 12338: 12305: 12274: 12266: 12248: 12224: 12174: 12159: 12149: 12119: 12114: 12079: 11964: 11959: 11934: 11904: 11889: 11746: 11706: 11691: 11686: 11681: 11676: 11646: 11626: 11551: 11539: 11523: 11507: 11477: 11379: 11344: 11334: 11204: 10614:"New Hope for Treatment-Resistant Depression: Guessing Right on Ketamine" 10584:"Ketamine for treatment-resistant depression: When and where is it safe?" 10406: 10402: 9463: 9273:"Comparative pharmacology of the ketamine isomers. Studies in volunteers" 9208: 7725:
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3241: 3197: 3004: 2988: 2879: 2864: 2828: 2772: 2718: 2602: 2086: 1771: 1751: 1690: 1674: 1496: 1479: 1366: 1194: 1174: 1147: 1109: 455: 29: 30762: 10519:"Matthew Perry died from the 'acute effects of ketamine,' autopsy finds" 9451: 9034:. Springer Science & Business Media. 6 December 2012. pp. 23–. 7849: 7646: 7552: 6592:
Jat KR, Chawla D, et al. (Cochrane Airways Group) (November 2012).
4759: 2744: 2578: > 60 μM), it has been suggested that it may interact with 692: 38802: 38726: 38640: 38583: 38566: 38562: 38495: 38433: 38344: 38329: 38319: 38309: 38299: 38274: 38254: 38234: 38181: 38171: 37984: 37979: 37954: 37762: 37642: 37602: 37542: 37522: 36676: 36666: 36616: 36576: 36447: 36422: 36402: 36387: 36382: 36293: 36262: 36254: 36154: 36118: 36082: 36065: 35974: 35899: 35889: 35884: 35879: 35833: 35759: 35666: 35436: 35431: 35140: 35120: 34989: 34521: 34486: 34415: 34385: 34350: 34068: 34048: 33990: 33970: 33406: 33396: 33356: 33346: 32557: 32294: 32028: 31920: 31393: 31238: 31186: 30816: 30689: 30675: 30661: 30567: 30563: 30559: 30513: 30483: 30478: 30473: 30453: 30423: 30413: 30373: 30358: 30338: 30225: 30205: 30175: 30155: 30135: 30095: 30043: 30028: 30023: 29983: 29947: 29919: 29848: 29825: 29820: 29772: 29744: 29739: 29734: 29719: 29709: 29577: 29572: 29517: 29454: 29397: 29378: 29355: 29350: 29340: 29330: 29291: 29254: 29249: 29244: 29195: 29190: 29172: 29109: 29094: 29079: 29013: 28993: 28924: 28914: 28883: 28837: 28824: 28793: 28758: 28641: 28636: 28611: 28561: 28556: 28531: 28486: 28411: 28130: 28104: 28099: 28081: 28066: 28048: 28032: 27836: 27806: 27796: 27693: 27638: 27573: 27568: 27468: 27399: 27379: 27344: 27339: 27334: 27304: 27254: 27211: 27176: 27127: 27122: 27082: 27049: 27044: 27034: 27014: 27009: 26942: 26917: 26742: 26689: 26679: 26644: 26613: 26599: 26574: 26569: 26549: 26544: 26456: 26426: 26401: 26282: 26193: 26173: 26150: 25993: 25968: 25958: 25913: 25903: 25888: 25803: 25697: 25625: 25620: 25595: 25565: 25555: 25530: 25515: 25490: 25460: 25435: 25425: 25385: 25365: 25355: 25335: 25265: 25250: 25069: 25049: 25044: 25019: 24949: 24888: 24868: 24823: 24813: 24808: 24748: 24738: 24668: 24583: 24432: 24422: 24412: 24402: 24367: 24357: 24322: 24292: 24282: 24277: 24214: 24058: 24033: 24028: 24023: 24013: 23998: 23968: 23886: 23876: 23871: 23821: 23776: 23756: 23726: 23676: 23656: 23611: 23536: 23426: 23416: 23234: 23190: 23155: 23082: 23045: 23005: 22975: 22952: 22916: 22865: 22850: 22734: 22719: 22689: 22679: 22674: 22629: 22624: 22563: 22558: 22543: 22517: 22487: 22482: 22467: 22462: 22437: 22432: 22402: 22397: 22377: 22372: 22296: 22275: 22258: 22253: 22136: 22126: 22010: 21995: 21965: 21955: 21950: 21905: 21900: 21834: 21829: 21788: 21768: 21753: 21728: 21712: 21687: 21682: 21560: 21550: 21535: 21480: 21470: 21460: 21440: 21430: 21415: 21410: 21333: 21323: 21318: 21131: 21024: 21019: 20874: 20846: 20796: 20781: 20758: 20753: 20748: 20681: 20651: 20641: 20580: 20516: 20501: 20481: 20426: 20396: 20381: 20356: 20341: 20306: 20301: 20261: 20256: 20226: 20211: 20171: 20149: 20112: 20082: 20067: 20047: 19805: 19775: 19758: 19748: 19503: 19493: 19468: 19423: 19300: 19285: 19280: 19260: 19219: 19209: 19199: 19179: 19174: 19134: 19129: 19089: 19079: 19064: 19004: 18979: 18728: 18656: 18651: 18587: 18582: 18572: 18567: 18547: 18368: 18357: 18353: 18320: 18205: 18200: 18175: 18165: 18140: 18135: 18130: 18071: 18061: 18043: 18038: 18008: 17998: 17958: 17923: 17878: 17868: 17863: 17858: 17843: 17808: 17733: 17677: 17654: 17622: 17549: 17509: 17467: 17457: 17432: 17404: 17364: 17349: 17269: 17264: 17204: 17184: 17169: 17159: 17024: 17014: 16942: 16937: 16932: 16922: 16882: 16837: 16832: 16744: 16724: 16664: 16654: 16584: 16564: 16549: 16539: 16529: 16514: 16499: 16489: 16479: 16469: 16428: 16423: 16418: 16393: 16373: 16353: 16279: 16269: 16254: 16244: 16196: 16144: 16079: 16004: 15994: 15984: 15964: 15939: 15934: 15914: 15894: 15864: 15633: 15623: 15618: 15603: 15558: 15553: 15482: 15411: 15406: 15396: 15350: 15345: 15335: 15320: 15315: 15285: 15255: 15225: 15205: 15124: 15094: 14934: 14929: 14924: 14919: 14914: 14894: 14864: 14854: 14814: 14809: 14804: 14799: 14784: 14769: 14724: 14719: 14714: 14709: 14674: 14664: 14659: 14644: 14568: 14532: 14493: 14472: 14426: 14380: 14344: 14292: 14241: 14226: 14191: 14100: 14030: 14025: 14010: 14005: 13958: 13935: 13909: 13894: 13848: 13822: 13817: 13812: 13807: 13802: 13797: 13644: 13624: 13584: 13559: 13524: 13514: 13459: 13449: 13444: 13434: 13409: 13374: 13329: 13324: 13304: 13289: 13249: 13214: 13146: 13131: 13121: 12874: 12864: 12809: 12769: 12754: 12532: 12512: 12477: 12370: 12358: 12346: 12253: 12242: 12238: 12179: 12074: 12069: 12049: 11954: 11826: 11781: 11761: 11711: 11666: 11616: 11612: 11600: 11531: 11511: 11499: 11457: 11414: 11404: 11399: 11394: 11369: 11304: 11244: 11189: 11164: 11149: 7936: 6409: 6034: 5649: 5632: 5573: 5556: 5376: 5359: 5151:"Ketamine: Current applications in anesthesia, pain, and critical care" 4099: 3738: 3237: 3233: 3193: 3113:. At sufficiently high doses, users may experience what is called the " 3061: 2912: 2904: 2800: 2753: 2676: 2594: 1908: 1795: 1775: 1767: 1731: 1727: 1723: 1694: 1686: 1653: 1581: 1577: 1520: 1500: 1369:
nasal spray products containing ketamine intended to treat depression.
1316: 1311: 1151: 1043: 953: 943: 897: 703: 616: 609: 448: 192: 35267: 11010:
Comparative Biochemistry and Physiology. Toxicology & Pharmacology
10952:
Standard Operating Procedure No. 1 Anesthesia and Analgesia in Rodents
10002:"Govt makes notorious 'date rape' drug ketamine harder to buy or sell" 9906:"Order Amending Schedule I to the Controlled Drugs and Substances Act" 9401: 8999: 8956: 8818: 6856: 6594:"Ketamine for management of acute exacerbations of asthma in children" 6509: 6322:. Multidisciplinary Association for Psychedelic Studies. p. 122. 6009: 3839:
Quibell R, Prommer EE, Mihalyo M, Twycross R, Wilcock A (March 2011).
3690: 3626: 3181:, which refers to a compound capable of promoting rapid and sustained 38748: 38744: 38679: 38529: 38448: 38438: 38394: 38384: 38369: 38314: 38249: 38219: 38209: 38164: 38089: 37969: 37959: 37949: 37924: 37792: 37787: 37757: 37732: 37692: 37672: 37582: 37552: 37547: 37512: 37487: 37062: 37057: 37052: 36661: 36641: 36586: 36511: 36471: 36412: 36397: 36372: 36313: 36267: 36174: 36159: 36149: 35964: 35959: 35949: 35869: 35864: 35823: 35791: 35786: 35739: 35698: 35646: 35636: 35623: 35618: 35577: 35547: 35510: 35483: 35473: 35394: 35389: 35384: 35125: 35080: 34395: 34390: 34380: 34375: 34370: 34360: 34355: 34345: 34340: 34272: 33541: 33341: 33068: 33024: 32572: 32567: 32142: 32127: 32102: 31950: 31945: 31930: 31925: 31885: 31862: 31799: 31656: 31629: 31513: 31371: 31354: 31327: 31243: 31206: 31196: 31169: 31140: 31101: 31088: 31066: 31037: 30834: 30577: 30463: 30398: 30393: 30368: 30363: 30353: 30348: 30258: 30200: 30165: 30145: 30110: 30066: 29924: 29881: 29853: 29787: 29729: 29582: 29542: 29537: 29391: 29239: 29200: 29144: 29074: 29008: 29003: 28980: 28962: 28947: 28919: 28898: 28893: 28888: 28847: 28803: 28591: 28566: 28431: 28360: 28288: 28213: 28125: 28012: 27984: 27974: 27946: 27831: 27826: 27816: 27673: 27658: 27643: 27618: 27548: 27463: 27443: 27394: 27329: 27324: 27239: 27107: 27004: 26984: 26957: 26937: 26862: 26762: 26752: 26722: 26664: 26659: 26539: 26534: 26411: 26406: 26356: 26328: 26257: 26218: 26213: 26188: 26183: 26110: 26018: 26008: 25898: 25808: 25722: 25680: 25670: 25610: 25600: 25590: 25560: 25550: 25545: 25500: 25470: 25350: 25330: 25230: 25225: 25180: 25099: 25094: 25054: 25039: 25014: 24944: 24883: 24853: 24803: 24793: 24788: 24653: 24543: 24508: 24503: 24447: 24372: 24352: 24347: 24317: 24247: 24209: 24189: 24184: 24124: 24108: 24098: 24043: 23953: 23901: 23896: 23831: 23786: 23766: 23646: 23636: 23481: 23222: 23170: 23140: 23135: 23055: 23037: 23033: 22990: 22948: 22891: 22840: 22759: 22729: 22593: 22512: 22502: 22497: 22492: 22417: 22412: 22292: 22288: 22177: 22167: 22116: 22035: 22005: 21869: 21819: 21738: 21733: 21702: 21697: 21657: 21555: 21545: 21510: 21435: 21405: 21338: 21298: 21262: 21167: 21152: 21126: 21090: 21080: 21009: 21004: 20999: 20994: 20671: 20661: 20619: 20545: 20535: 20461: 20456: 20416: 20391: 20386: 20336: 20311: 20241: 20216: 20206: 20181: 20176: 20166: 20042: 19927: 19912: 19892: 19877: 19872: 19763: 19588: 19583: 19529: 19418: 19413: 19408: 19366: 19275: 19270: 19245: 19154: 19094: 19074: 19069: 19059: 19049: 19024: 18952: 18914:
Tooltip α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor
18748: 18694: 18610: 18493: 18483: 18414: 18343: 18305: 18280: 18270: 18195: 18145: 18090: 18066: 17993: 17903: 17898: 17893: 17853: 17848: 17838: 17823: 17682: 17554: 17534: 17514: 17504: 17462: 17442: 17359: 17154: 17069: 17059: 17039: 16977: 16962: 16952: 16912: 16897: 16867: 16852: 16847: 16842: 16768: 16709: 16659: 16649: 16644: 16629: 16619: 16599: 16589: 16569: 16544: 16174: 16139: 16119: 16084: 16074: 16039: 16024: 15693: 15673: 15638: 15583: 15578: 15533: 15487: 15477: 15270: 15265: 15210: 15170: 15089: 15079: 15069: 15059: 14974: 14849: 14789: 14779: 14754: 14744: 14734: 14694: 14634: 14629: 14548: 14503: 14446: 14441: 14375: 14370: 14365: 14349: 14307: 14302: 14196: 14181: 14080: 14045: 13945: 13873: 13868: 13484: 13479: 13454: 13429: 13424: 13394: 13344: 13334: 13314: 13184: 12969: 12964: 12954: 12779: 12759: 12749: 12744: 12699: 12350: 12330: 12300: 12270: 12262: 12164: 12124: 12084: 12029: 11949: 11894: 11851: 11796: 11671: 11661: 11636: 11592: 11543: 11535: 11495: 11482: 11309: 11259: 11214: 11199: 8898: 6008:
Singh I, Morgan C, Curran V, Nutt D, Schlag A, McShane R (May 2017).
4848:"Use of ketamine in severe status asthmaticus in intensive care unit" 4779: 4300:
Hibicke M, Landry AN, Kramer HM, Talman ZK, Nichols CD (March 2020).
3267:
Concise Dictionary of Pharmacological Agents: Properties and Synonyms
3166: 3134: 3039: 2935: 2846: 2792:
independent of CYP2B6 activity, unlike subcutaneous ketamine levels.
2768: 2661: 2658: 2472:
Tooltip Hyperpolarization-activated cyclic nucleotide-gated channel 1
1763: 1698: 1689:
potentiates psychotomimetic effects of a low dose of ketamine, while
1682: 1565: 1488: 1458: 1453: 1447: 1354:
Ketamine may partially improve depressive symptoms among people with
1294:, although its effect is transient. Intravenous ketamine infusion in 638: 540: 428: 209: 168: 81: 30747: 29902: 29755: 6745: 38792: 38736: 38691: 38618: 38570: 38517: 38428: 38379: 38304: 38269: 38130: 38125: 38099: 38084: 38079: 38067: 37939: 37872: 37767: 37737: 37702: 37697: 37662: 37537: 36726: 36581: 36491: 36452: 36407: 36377: 36144: 35969: 35874: 35859: 35854: 35781: 35734: 35693: 35661: 35468: 35232: 35100: 34297: 34282: 34267: 34262: 34219: 33331: 32071: 31965: 31867: 31590: 31521: 31479: 31437: 31432: 31397: 31211: 31118: 31078: 31054: 31007: 30902: 30871: 30328: 30284: 29993: 29836: 29431: 29426: 29286: 29185: 28957: 28952: 28929: 28878: 28852: 28842: 28651: 28646: 28626: 28541: 28521: 28470: 28283: 28268: 28027: 28007: 27979: 27908: 27898: 27821: 27735: 27653: 27608: 27498: 27458: 27453: 27369: 27077: 26709: 26694: 26416: 26208: 25953: 25863: 25843: 25833: 25788: 25717: 25510: 25405: 25370: 25360: 25240: 25064: 24959: 24934: 24873: 24858: 24768: 24688: 24658: 24638: 24608: 24553: 24533: 24498: 24387: 24312: 24297: 24219: 24199: 24068: 24063: 24048: 24018: 23988: 23948: 23816: 23651: 23561: 23496: 23466: 23351: 23209: 23160: 23150: 23049: 22995: 22934: 22724: 22714: 22507: 22300: 22229: 22000: 21990: 21692: 21677: 21642: 21500: 21495: 21485: 21257: 21014: 20816: 20614: 20521: 20331: 20246: 20161: 20077: 19967: 19849: 19780: 19770: 19632: 19498: 19396: 19204: 18419: 18225: 18220: 18180: 18095: 17943: 17818: 17756: 17139: 17104: 17009: 16624: 16554: 16524: 16484: 16378: 16169: 16129: 16109: 15683: 15518: 15436: 15370: 15049: 15024: 14999: 14989: 14699: 14614: 14524: 14462: 14457: 14431: 14282: 14266: 14130: 13971: 13863: 13827: 13792: 13638: 13564: 13369: 13189: 12944: 12934: 12894: 12889: 12879: 12844: 12794: 12789: 12694: 12526: 12472: 12448: 12204: 12134: 11994: 11731: 11651: 11620: 11578: 11467: 11052: 10441:"The Sad Demise of Nancy Lee, One of Britain's Ketamine Casualties" 8803:"Ketamine and phencyclidine: the good, the bad, and the unexpected" 5672:
Radvansky BM, Shah K, Parikh A, Sifonios AN, Le V, Eloy JD (2015).
5102: 4845: 3608: 3154: 3117:", a state of dissociation with visual and auditory hallucination. 2726: 2673: 2519:
The smaller the value, the stronger the interaction with the site.
1678: 1624: 1596: 1541: 1508: 1241: 1182: 1167: 1159: 1066: 760: 752: 683: 109: 7676:
Zanos P, Thompson SM, Duman RS, Zarate CA, Gould TD (March 2018).
6842: 6490: 2827:
to form the corresponding bromoketone, which is then reacted with
920: 38762: 38740: 38650: 38596: 38509: 38374: 38147: 38135: 38003: 37867: 37847: 37842: 37777: 37772: 37707: 37677: 37667: 37627: 37532: 37469: 37464: 37454: 37439: 37434: 37414: 37409: 37404: 37379: 37374: 37364: 37359: 37349: 37339: 37324: 37314: 37309: 37304: 37294: 37289: 37284: 37279: 37269: 37264: 37259: 37254: 37249: 37244: 37234: 37229: 37224: 37219: 37214: 37209: 37204: 37199: 37194: 37189: 37184: 37179: 37174: 37169: 37164: 37159: 37031: 37021: 37011: 37001: 36996: 36991: 36976: 36966: 36956: 36951: 36946: 36941: 36936: 36636: 36631: 36626: 36621: 36367: 36240: 35979: 35344: 35292: 35227: 35024: 34576: 34146: 34126: 34121: 33858: 33823: 33813: 33803: 33798: 33793: 33783: 33546: 33511: 33501: 33486: 33466: 33391: 32182: 31701: 31684: 31679: 31664: 31612: 31602: 31585: 31457: 31298: 31293: 31226: 31152: 30972: 30892: 30150: 29557: 29532: 29402: 29387: 29134: 29064: 28696: 28668: 28491: 28406: 28251: 27890: 27299: 27279: 27274: 27181: 27117: 26882: 26857: 26852: 26847: 26842: 26837: 26832: 26777: 26594: 26559: 26381: 26262: 26140: 25823: 25707: 25485: 25475: 24703: 24633: 24568: 24518: 24377: 24129: 24103: 24093: 24078: 23983: 23796: 23771: 23521: 23401: 23015: 22845: 22798: 22794: 22744: 22739: 22694: 22684: 22644: 22573: 22452: 22121: 22074: 22070: 22020: 22015: 21970: 21960: 21920: 21844: 21763: 21525: 21515: 21505: 21475: 21420: 21242: 21237: 21232: 21227: 21222: 21217: 21212: 21172: 21070: 20989: 20860: 20706: 20696: 20676: 20631: 20117: 19732: 19717: 19683: 19617: 19508: 19386: 19104: 19034: 19014: 18962: 18488: 18310: 18110: 17635: 17034: 16972: 16634: 16614: 16310: 16181: 15548: 15386: 15175: 15004: 14774: 14624: 14619: 14588: 13990: 13889: 13884: 13634: 13614: 13194: 13165: 13019: 13014: 13009: 13004: 12994: 12898: 12784: 12719: 12714: 12522: 12502: 12354: 12129: 12014: 11816: 11811: 11806: 11801: 11249: 7131:
Hui TW, Short TG, Hong W, Suen T, Gin T, Plummer J (March 1995).
5401:"Clinical Uses of Ketamine in Children: A Narrative Review - PMC" 4081:
Sachdeva B, Sachdeva P, Ghosh S, Ahmad F, Sinha JK (March 2023).
3529:"Ketamine Hydrochloride: Martindale: The Complete Drug Reference" 3225: 2836: 2824: 2796: 1842:(AMPA receptors), which in turn modulate a variety of downstream 1738:
NMDA receptor pore blocker than arketamine. Pore blocking of the
1557: 1163: 1154:
decrease psychotomimetic effects and can be counteracted also by
1070: 33263: 11115: 8713:"Ketamine: its mechanism(s) of action and unusual clinical uses" 7450: 5017: 1058:
antagonist which accounts for most of its psychoactive effects.
37: 38537: 38521: 38513: 38294: 38259: 38196: 38120: 38052: 38027: 37887: 37877: 37822: 37742: 37607: 37562: 37557: 37517: 37502: 37138: 37133: 37128: 37123: 37118: 37113: 37108: 37103: 37098: 36921: 36916: 36911: 36906: 36901: 36886: 36876: 36866: 36856: 36851: 36846: 36811: 36611: 36357: 35998: 35287: 35277: 35019: 34958: 34848: 34789: 34779: 33937: 33888: 33883: 33763: 33758: 33753: 33738: 33733: 33728: 33703: 33668: 33663: 33658: 33653: 33648: 33643: 33638: 33491: 33476: 33471: 33441: 33436: 33431: 33416: 33401: 33386: 33366: 32132: 32066: 31535: 31381: 31361: 31123: 31047: 31012: 30951: 29874:
Tooltip Noradrenergic and specific serotonergic antidepressants
29697: 28337: 28239: 28230: 27999: 27729: 27284: 27269: 27186: 27147: 27112: 26989: 26907: 26902: 26867: 26827: 26529: 26391: 26376: 26371: 26242: 26135: 25798: 25465: 25280: 24939: 24863: 24848: 24838: 24613: 24204: 24083: 23701: 23581: 23025: 22754: 22699: 22442: 22280: 22030: 21975: 21783: 21530: 21207: 20736: 20636: 20009: 19740: 19722: 19699: 18994: 18989: 18314: 17578:
Tooltip G protein-coupled inwardly rectifying potassium channel
17427: 17423:
Tooltip G protein-coupled inwardly rectifying potassium channel
17099: 17019: 16902: 16892: 16674: 16443: 15688: 14654: 14508: 14385: 13950: 13224: 13044: 12854: 12639: 12230: 11791: 11442: 8133: 7352: 7228: 5723:
Lee M, Silverman SM, Hansen H, Patel VB, Manchikanti L (2011).
5505: 5399:
Bali A, Dang AK, Gonzalez DA, Kumar R, Asif S (24 April 2024).
5108: 4594: 4354:
Morgan CJ, Curran HV (January 2012). "Ketamine use: a review".
3213: 3114: 3050: 3042:, ketamine is listed as a schedule 8 controlled drug under the 2776: 2765: 2761: 1883: 1516: 1220: 1062: 791: 439: 435: 10851:
The Veterinary Clinics of North America. Small Animal Practice
7678:"Convergent Mechanisms Underlying Rapid Antidepressant Action" 5949: 5360:"The cardiovascular effects of ketamine in hypotensive states" 4403: 3053:, ketamine is classified as a Schedule I narcotic, since 2005. 1840:α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors 38533: 38154: 37837: 37832: 37827: 37802: 37797: 37752: 37747: 37637: 36816: 36457: 36442: 36362: 36108: 36002: 35994: 35984: 35322: 35317: 35029: 34979: 34953: 34948: 34774: 34769: 33908: 33893: 33718: 33683: 33623: 33608: 33481: 33456: 31268: 31106: 31059: 30922: 30065: 28571: 28278: 28243: 27871: 27244: 27171: 26822: 26524: 26396: 25998: 25893: 25635: 25390: 25255: 24628: 24578: 24538: 24302: 23993: 23937: 23846: 23531: 23526: 20731: 20156: 19947: 19673: 19483: 19009: 18999: 18794: 17284: 17054: 16907: 15508: 14609: 13594: 11154: 10645:"Ketamine for Treatment-Resistant Depression: a New Advocate" 10468:"Drug related deaths involving ketamine in England and Wales" 9181:
Idvall J, Ahlgren I, Aronsen KR, Stenberg P (December 1979).
9090: 4648: 3838: 2560:
Ketamine may interact with and inhibit the NMDAR via another
2495: 1588: 911: 771: 553: 547: 424: 20: 23337: 18896: 17702: 10313:
Sisters of the Extreme: Women Writing on the Drug Experience
9940: 9180: 8426: 8377: 7935: 7724: 7586:"Overcoming Depression by Inhibition of Neural Burst Firing" 6242: 5630: 2629:
mechanisms, namely through antagonism of the NMDA receptor.
816: 38636: 38264: 37817: 37812: 37807: 37782: 36781: 36230: 36196: 36179: 35441: 35009: 35004: 34999: 34823: 34813: 34794: 34784: 33898: 33723: 33708: 33698: 33688: 33678: 33673: 33633: 33628: 33618: 33613: 33598: 33578: 32157: 31674: 31288: 31157: 31145: 31113: 30931: 30854: 30849: 29935: 27221: 26714: 25400: 23099: 20624: 20451: 20037: 20024: 19658: 19478: 19448: 19438: 19351: 19184: 19149: 19139: 18937: 18630:
Tooltip Cystic fibrosis transmembrane conductance regulator
18552: 17597: 17255: 17217: 17000: 10740: 9270: 9183:"Ketamine infusions: pharmacokinetics and clinical effects" 8675: 7269: 7047:
Joseph P, Binu R, Sebastian T, Fahmy H (11 December 2017).
6946: 5968:(3). American Psychiatric Association Publishing: 243–250. 5671: 5273: 4454: 2831:
in an aqueous solution to form the methylimino derivative,
2687: 2587: 1823: 1227:, and with severe reactive airway disease including active 743: 29803: 21621: 18526: 15831: 11128: 9221: 9054: 8625: 7049:"Multiorgan Dysfunction Related to Chronic Ketamine Abuse" 6342: 5862: 4080: 2553:
isomer is a more potent anesthetic and analgesic than its
1798:
with negligible affinity for the NMDA receptor but potent
1568:. The damage to the bladder wall has similarities to both 37944: 34858: 33496: 32257:
Council of the European Union decisions on designer drugs
31940: 31366: 31133: 19862: 14436: 12652: 8751: 8478: 8281: 8236:
The Journal of Pharmacology and Experimental Therapeutics
8084: 6190: 5065: 4745: 4556:
Orhurhu VJ, Vashisht R, Claus LE, Cohen SP (April 2022).
4555: 4299: 3217: 34181: 23070: 16796: 10955:, Washington College, 2012, pp. 1–2, archived from 9969:"Ketamine drug brought under 'Schedule X' to curb abuse" 9711: 8855:
International Journal of Psychiatry in Clinical Practice
8852: 7675: 7095: 7046: 6076: 4507:
Bobo WV, Riva-Posse P, Goes FS, Parikh SV (April 2020).
4506: 4212: 3989: 3270:. Springer Science & Business Media. pp. 159–. 3133:(among others) have written extensively about their own 2991:
consultant. It was known by the developmental code name
2839:
or another suitable high-boiling solvent, upon which an
2191: 2155: 1552:. The typical symptoms of ketamine-induced cystitis are 1365:
issued an alert to health care professionals concerning
26580: 17487: 17307: 10207: 10145: 9435: 8378:
Yamakura T, Chavez-Noriega LE, Harris RA (April 2000).
8000: 7879: 5725:"A comprehensive review of opioid-induced hyperalgesia" 5722: 4809:
Rosenbaum SB, Gupta V, Palacios JL (2020). "Ketamine".
4158: 3097:
Ketamine in society and culture § Recreational use
2930:
of a given enantiomer of ketamine can vary between its
1114:
World Health Organization's List of Essential Medicines
35810: 22612:
Serotonin–norepinephrine–dopamine reuptake inhibitors:
21888:
Serotonin–norepinephrine–dopamine reuptake inhibitors:
20154:
Uncompetitive pore blockers (mostly dizocilpine site):
13075: 12671: 12020:
Octatropine methylbromide (anisotropine methylbromide)
10283: 8317: 6998:"Chronic biliary colic associated with ketamine abuse" 6439: 4971: 4808: 4213:
Green SM, Roback MG, Kennedy RM, Krauss B (May 2011).
3724: 1818:
receptor and downstream effects on regulators such as
1328:
in 2019. Esketamine was approved as a nasal spray for
19:
For the functional group referred to as ketimine, see
38834: 34035: 33957: 27222: 26715: 22331: 19560: 17784: 11072: 10306: 8752:
Orser BA, Pennefather PS, MacDonald JF (April 1997).
7501:"Arketamine – Jiangsu Hengrui Medicine – AdisInsight" 7493: 6543: 6295:. US Food and Drug Administration. 16 February 2022. 6007: 5597: 5398: 2787:. Low oral bioavailability of ketamine is due to the 2597:
at concentrations of up to 10,000 nM. Moreover,
1929: 1807:, a part of the brain responsible for inhibiting the 1096:
Ketamine was first synthesized in 1962, derived from
29907:
Tooltip Serotonin antagonist and reuptake inhibitors
29760:
Tooltip Serotonin–norepinephrine reuptake inhibitors
20968: 10018: 9875: 7731:
The International Journal of Neuropsychopharmacology
7537:"Mechanisms of ketamine action as an antidepressant" 7398: 6698: 6696: 6694: 6692: 6690: 4293: 3375:"Ketamine as an adjuvant to opioids for cancer pain" 30241: 29841:
Tooltip Norepinephrine–dopamine reuptake inhibitors
27405: 9943:. Canadian Society of Customs Brokers. 2 May 2005. 8318:Hirota K, Hashimoto Y, Lambert DG (December 2002). 8229: 8041: 7780:"BDNF – a key transducer of antidepressant effects" 6888:"Ketamine-induced vesicopathy: a literature review" 4923: 3491: 3489: 3487: 3485: 3483: 2605:have found no interaction between ketamine and the 2525:Ketamine principally acts as a pore blocker of the 1564:sometimes accompanied by pain during urination and 1146:effects limit the acceptance of ketamine; however, 671: 35773: 34332: 21610: 10182: 9475: 9458: 9383: 7773: 7394: 7392: 4852:Iranian Journal of Allergy, Asthma, and Immunology 4208: 4206: 4204: 3481: 3479: 3477: 3475: 3473: 3471: 3469: 3467: 3465: 3463: 3439: 3372: 3288: 2672:studies have shown mixed results on inhibition of 2636:receptors is controversial. Early research by the 2409: 1519:movements (greater than 10% of people) and rarely 35497: 34254: 30083: 27350: 27058: 20947: 18819: 18393: 10189:. Los Angeles: Health Information Press. p.  9848: 9822: 6687: 6165:. US Food and Drug Administration. 5 March 2019. 5603: 5314: 4037:. Vol. 6. Academic Press. pp. 297–322. 583:)-2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone 38858: 30306: 26459:(met-enkephalin releaser/degradation stabilizer) 18457: 13757: 12210:Scopolamine butylbromide (hyoscine butylbromide) 9834:. Taylor & Francis. 2000. pp. 584–585. 9831:Index Nominum 2000: International Drug Directory 9130: 9128: 8985: 8894: 8892: 8848: 8846: 8671: 8669: 8667: 8665: 8373: 8371: 8369: 8367: 8365: 8363: 8277: 8275: 8225: 8223: 8221: 8219: 8217: 8175: 8173: 7931: 7929: 7927: 7925: 7130: 6640: 5763: 5251:(blog). Critical Care Compendium. Archived from 5149:Kurdi MS, Theerth KA, Deva RS (September 2014). 5148: 4076: 4074: 4072: 4070: 4068: 4066: 4064: 4062: 3668: 3666: 3664: 3662: 3660: 3658: 3656: 3654: 3564:Toxicological Aspects of Drug-Facilitated Crimes 1862:(BDNF) and activation of its signaling receptor 1332:in the United States and elsewhere in 2019 (see 1088:Ketamine is used as a recreational drug for its 1042:used medically for induction and maintenance of 651: 38493: 34113: 30643: 29702:Tooltip Selective serotonin reuptake inhibitors 18857:Transient receptor potential channel modulators 12235:Tooltip Selective serotonin reuptake inhibitors 11003: 10976: 10791: 10213:References for recreational use in literature: 10077:"Party drug ketamine to be upgraded to Class B" 9881:Legal status of ketamine in Canada references: 9685:. Center for Substance Abuse Research (CESAR); 9573:Disposition of Toxic Drugs and Chemicals in Man 8474: 8472: 7996: 7994: 7624: 7530: 7528: 7526: 7524: 7522: 7446: 7444: 7389: 7348: 7346: 7304: 7302: 6838: 6836: 6834: 6832: 6003: 6001: 5908: 5906: 5904: 5902: 5858: 5856: 5854: 5501: 5499: 5497: 5144: 5142: 5140: 5061: 5059: 5057: 5055: 5013: 5011: 5009: 4967: 4965: 4963: 4700: 4698: 4696: 4694: 4644: 4642: 4640: 4638: 4636: 4634: 4564:. Treasure Island (FL): StatPearls Publishing. 4502: 4500: 4450: 4448: 4446: 4444: 4399: 4397: 4395: 4393: 4201: 4154: 4152: 4150: 4148: 4146: 4144: 3985: 3983: 3981: 3979: 3604: 3602: 3600: 3598: 3596: 3594: 3592: 3590: 3588: 3495: 3460: 3192:activity in rats, with an effect comparable to 2570:Although ketamine is a very weak ligand of the 2378: 1503:and can be counteracted by pretreatment with a 1133:is not required. The effect of ketamine on the 626: 600: 38982:Opioid receptor positive allosteric modulators 35680: 35534: 31805:Legal history of cannabis in the United States 27774: 27360: 27068: 23315: 19812: 19797: 13570:Trimetaphan camsilate (trimethaphan camsylate) 10883: 10683: 10460: 10430: 10428: 9311: 9176: 9174: 8576: 5554: 4256: 3892: 3890: 3888: 3834: 3832: 3830: 3828: 3826: 3824: 3822: 3820: 3720: 3718: 1722:Ketamine is a mixture of equal amounts of two 126: 38957:World Health Organization essential medicines 38479: 35455: 35418: 33279: 30778: 29646: 28198: 27760: 26498: 26484: 23301: 22536:Serotonin–norepinephrine reuptake inhibitors: 22320: 21812:Serotonin–norepinephrine reuptake inhibitors: 21640:Selective norepinephrine reuptake inhibitors: 20933: 18882: 18799:Tooltip Transient receptor potential channels 17289:Tooltip Inwardly rectifying potassium channel 15798: 13743: 13711:Acetylcholine metabolism/transport modulators 12625: 12599:Acetylcholine metabolism/transport modulators 11101: 11049:— from the United States DEA, via Archive.org 10910: 10642: 10139: 9779: 9705: 9621: 9584: 9377: 9125: 9084: 9022: 8979: 8936: 8889: 8843: 8794: 8710: 8662: 8570: 8521: 8420: 8360: 8311: 8272: 8214: 8170: 8127: 8078: 8035: 7922: 7873: 7826: 7820: 7583: 6885: 6702: 4059: 3939: 3651: 3257: 3224:", a mixture of drugs used for anesthetising 2833:1-(2-Chloro-N-methylbenzimidoyl)cyclopentanol 1535: 1216:are good candidates for ketamine anesthesia. 30805: 21726:Norepinephrine–dopamine reuptake inhibitors: 20957: 17707:Tooltip Tandem pore domain potassium channel 14489:Deoxyepinephrine (N-methyldopamine, epinine) 13931:Deoxyepinephrine (N-methyldopamine, epinine) 13706:Muscarinic acetylcholine receptor modulators 10970: 9314:"Does ketamine metabolite II exist in vivo?" 9305: 9264: 9215: 9048: 8800: 8704: 8469: 7991: 7767: 7718: 7669: 7618: 7577: 7519: 7441: 7343: 7299: 7263: 7222: 7179: 7053:Baylor University Medical Center Proceedings 6829: 6788: 6739: 6537: 6433: 6155: 6070: 5998: 5955: 5899: 5851: 5716: 5665: 5624: 5494: 5449: 5193: 5137: 5052: 5006: 4960: 4691: 4631: 4497: 4441: 4390: 4353: 4252: 4250: 4141: 3976: 3585: 3496:Mathew SJ, Zarate Jr CA (25 November 2016). 3373:Bell RF, Eccleston C, Kalso EA (June 2017). 3101:At sub-anesthetic doses ketamine produces a 2657:are able to rapidly and powerfully suppress 2438: 113: 30677: 30494: 30434: 29940:Tooltip Serotonin modulator and stimulators 28212: 17605:Tooltip Calcium-activated potassium channel 12594:Nicotinic acetylcholine receptor modulators 10886:Veterinary Medicine, Small Animal Clinician 10425: 10361: 10223:The Scientist: A Metaphysical Autobiography 10101: 10031:Response to ACMD recommendation on ketamine 9630:"Ketamine: 50 Years of Modulating the Mind" 9490: 9171: 8179: 6995: 6879: 6598:The Cochrane Database of Systematic Reviews 6587: 6585: 6583: 6311: 6249:The Cochrane Database of Systematic Reviews 6197:The Cochrane Database of Systematic Reviews 5357: 4917: 4804: 4802: 4767: 4349: 4347: 4345: 3896: 3885: 3817: 3715: 3556: 3554: 3382:The Cochrane Database of Systematic Reviews 1642: 1324:– was approved as an antidepressant by the 1116:and is available as a generic medication. 16:Dissociative anesthetic and anti-depressant 38977:Psychedelics, dissociatives and deliriants 38882:Chemical substances for emergency medicine 38486: 38472: 33286: 33272: 32533:Arguments for and against drug prohibition 30785: 30771: 29808:Tooltip Norepinephrine reuptake inhibitors 29660: 29653: 29639: 28205: 28191: 27767: 27753: 26491: 26477: 23308: 23294: 21626:Tooltip Norepinephrine reuptake inhibitors 20940: 20926: 20899:Metabotropic glutamate receptor modulators 18889: 18875: 18531:Tooltip Calcium-activated chloride channel 16823:4-Aminopyridine (fampridine/dalfampridine) 15836:Tooltip Voltage-dependent calcium channels 15812: 15805: 15791: 13750: 13736: 12632: 12618: 12170:3-Quinuclidinyl thiochromane-4-carboxylate 11133:Tooltip Muscarinic acetylcholine receptors 11108: 11094: 10618:National Institute of Mental Health (NIMH) 10474:. Government of the United Kingdom. 2013. 9627: 9426: 8942: 8577:Chen X, Shu S, Bayliss DA (January 2009). 7534: 7180:Hong W, Short TG, Hui TW (December 1993). 7089: 7002:International Medical Case Reports Journal 6892:International Journal of Clinical Practice 6709:The American Journal of Emergency Medicine 6345:Current Neurology and Neuroscience Reports 6336: 6139:. European Medicines Agency. 8 July 2022. 5814: 5452:"Ketamine in status asthmaticus: A review" 4032: 3782: 3263: 2979:Ketamine was first synthesized in 1962 by 2919:-ketamine), has never been marketed as an 1495:. Psychotomimetic effects decrease adding 1307:for up to three days after the injection. 853: 830: 711: 30792: 20906:Glutamate metabolism/transport modulators 12657:Tooltip Nicotinic acetylcholine receptors 10817: 10768: 10758: 10717: 10660: 10581: 9677: 9675: 9655: 9645: 9409: 9329: 9288: 9239: 9198: 9108: 8826: 8769: 8728: 8602: 8553: 8496: 8452: 8395: 8335: 8255: 8197: 8110: 8018: 7974: 7964: 7905: 7848: 7803: 7750: 7701: 7601: 7560: 7476: 7424: 7326: 7246: 7197: 7173: 7148: 7072: 7023: 7013: 6972: 6903: 6812: 6797:"Ketamine-induced urologic insult (KIUI)" 6771: 6654: 6634: 6617: 6591: 6508: 6467: 6457: 6408: 6268: 6216: 6033: 5981: 5791: 5781: 5740: 5699: 5689: 5648: 5572: 5531: 5477: 5467: 5426: 5416: 5375: 5291: 5176: 5166: 5035: 4989: 4758: 4722: 4674: 4532: 4480: 4317: 4247: 4230: 4184: 4116: 4098: 3856: 3778: 3776: 3774: 3772: 3770: 3768: 3766: 3764: 3698: 3672: 3634: 3526: 3401: 3296:"Ketamine (Ketalar) Use During Pregnancy" 2752:In the body ketamine undergoes extensive 2582:on the monoamine transporters to produce 2019: 1987: 1958: 1605:intravesical (intra-bladder) instillation 1595:and, if the response is insufficient, by 731: 32507:Psilocybin decriminalization in the U.S. 32204: 30535: 23075:Tooltip Vesicular monoamine transporters 22350:Selective serotonin reuptake inhibitors: 19318: 16801:Tooltip Voltage-gated potassium channels 13200:Candocuronium iodide (chandonium iodide) 10914:Veterinary Pharmacology and Therapeutics 10792:Robertson SA, Taylor PM (October 2004). 10541: 10180: 10107: 9754: 9346: 7124: 6580: 6285: 6186: 6184: 5555:Sin B, Ternas T, Motov SM (March 2015). 5456:Indian Journal of Critical Care Medicine 4839: 4799: 4342: 3551: 2845: 2743: 2688:Relationships between levels and effects 2203:Tooltip Nicotinic acetylcholine receptor 2167:Tooltip Nicotinic acetylcholine receptor 1478: 1372: 38902:Drugs with unknown mechanisms of action 32543:Capital punishment for drug trafficking 31598:Neocannabinoid / synthetic cannabinoids 26620:Dehydroepiandrosterone sulfate (DHEA-S) 26585:Tooltip Calcitonin gene-related peptide 17495:Tooltip ATP-sensitive potassium channel 17315:Tooltip ATP-sensitive potassium channel 15378:Antiemetics/gastroprokinetics/sedatives 10979:American Journal of Veterinary Research 10392: 10039:Advisory Council on the Misuse of Drugs 9999: 9859:. Australian Government. October 2015. 9788:Expert Opinion on Investigational Drugs 9134: 8527: 7308: 6703:Strayer RJ, Nelson LS (November 2008). 6238: 6236: 5364:Canadian Anaesthetists' Society Journal 5242: 4739: 1895:Ketamine and biological targets (with K 826: 691: 38859: 32434:Office of National Drug Control Policy 32222:International drug control conventions 20629:Alcohols/volatile anesthetics/related: 13080:Tooltip negative allosteric modulators 12676:Tooltip positive allosteric modulators 10917:. John Wiley & Sons. p. 200. 10848: 10798:Journal of Feline Medicine and Surgery 10624:from the original on 10 September 2022 10557:Centre for Addiction and Mental Health 10516: 10367: 10337: 10014:from the original on 30 December 2013. 9672: 9496: 9373:from the original on 8 September 2017. 8801:Lodge D, Mercier MS (September 2015). 8745: 7584:Kim D, Cheong E, Shin HS (June 2018). 6928:from the original on 19 September 2018 6735:from the original on 8 September 2017. 6317: 4704: 4035:Analytical Profiles of Drug Substances 3873:from the original on 16 September 2018 3845:Journal of Pain and Symptom Management 3761: 3581:from the original on 8 September 2017. 3516:from the original on 8 September 2017. 3264:Morton IK, Hall JM (6 December 2012). 3203: 3014: 2903:compound. The more active enantiomer, 2895:In chemical structure, ketamine is an 2737:into the brain and other tissues. The 1717: 1511:. Ketamine anesthesia commonly causes 844: 332: 308: 38467: 33267: 32625: 32203: 31775:List of cannabis rights organizations 31722: 30804: 30766: 30752: 30751: 30630: 30534: 30305: 30064: 29677: 29634: 28186: 27748: 27733: 26472: 23289: 22336:Tooltip Serotonin reuptake inhibitors 20921: 19785:Other positive allosteric modulators: 19565:Tooltip N-Methyl-D-aspartate receptor 18870: 17789:Tooltip Voltage-gated sodium channels 15786: 13731: 12613: 11089: 11071: 11056: 10529:from the original on 28 December 2023 10248: 10216: 10074: 10056:from the original on 28 February 2014 10024: 9693:from the original on 12 November 2013 8711:Hirota K, Lambert DG (October 1996). 6953:Experimental and Therapeutic Medicine 6794: 6181: 6143:from the original on 23 November 2020 5443: 4926:Expert Review of Respiratory Medicine 4880: 4827:from the original on 12 November 2020 4787:from the original on 10 December 2014 4753:. Geneva: World Health Organization. 4033:Sass W, Fusari S (1977). "Ketamine". 3679:Psychiatry and Clinical Neurosciences 3560: 2733:After absorption ketamine is rapidly 2586:. However, no functional inhibition ( 1934:Tooltip N-Methyl-D-aspartate receptor 1046:. It is also used as a treatment for 799: 779: 320: 121: 104: 86: 33929: 20973:Tooltip Dopamine reuptake inhibitors 17724:12-O-Tetradecanoylphorbol-13-acetate 11057: 10931:from the original on 8 February 2023 9863:from the original on 19 January 2016 9785: 9687:University of Maryland, College Park 9070:10.1001/archpsyc.1994.03950030035004 6886:Middela S, Pearce I (January 2011). 6233: 5808: 5199: 4870:from the original on 6 October 2014. 3535:. London, UK: Pharmaceutical Press. 3421:from the original on 12 January 2024 1889: 1619:abuse has also been associated with 1408: 304:(Special prescription form required) 232: 33566: 30246:Tooltip Tetracyclic antidepressants 27410:Tooltip 3,4,5-Trimethoxyamphetamine 20526:Ifenprodil (NR2B) site antagonists: 16818:3,4-Diaminopyridine (amifampridine) 14980:Levomepromazine (methotrimeprazine) 10594:from the original on 31 August 2022 9947:from the original on 10 August 2014 9352: 6996:Ahamed AN, Yahya AA (2 June 2016). 6525:from the original on 29 August 2020 6299:from the original on 31 August 2022 5958:"Ketamine: A Review for Clinicians" 5317:Acta Anaesthesiologica Scandinavica 5245:"Intubation, Hypotension and Shock" 3539:from the original on 28 August 2021 3527:Brayfield A, ed. (9 January 2017). 3342:Ketamine is listed in Schedule III. 3284:from the original on 11 April 2017. 3090: 2748:Major routes of ketamine metabolism 2741:of ketamine is variable at 23–47%. 2712: 2632:Whether ketamine is an agonist of D 1712: 1065:-like state providing pain relief, 759: 751: 642: 13: 38552:voltage-dependent calcium channels 32327:Law Enforcement Action Partnership 22670:Didesmethylsibutramine (BTS-54505) 21946:Didesmethylsibutramine (BTS-54505) 21615:Tooltip Norepinephrine transporter 21376:Didesmethylsibutramine (BTS-54505) 19090:Pesampator (BIIB-104, PF-04958242) 9981:from the original on 14 April 2014 9767:from the original on 19 March 2022 9432:Synthesis of ketamine references: 9312:Stenberg P, Idvall J (July 1981). 7507:from the original on 13 April 2021 7315:The Journal of Clinical Psychiatry 5329:10.1111/j.1399-6576.1991.tb03385.x 4549: 4259:Expert Review of Neurotherapeutics 3567:. Elsevier Science. pp. 87–. 3502:. Springer. pp. 8–10, 14–22. 3200:at extremely high concentrations. 2795:After an intravenous injection of 2775:, which, in turn, is converted by 2414:Tooltip Norepinephrine transporter 1838:, which leads to an activation of 1474: 1225:chronic obstructive airway disease 1181:supports the use of ketamine as a 14: 38993: 38719:Glucocorticoids (corticosteroids) 33293: 32344:Students for Sensible Drug Policy 30631: 30088:Tooltip Tricyclic antidepressants 29297:Tetrahydrocannabinol (dronabinol) 27584:Chlorphenamine (chlorpheniramine) 27355:Tooltip N,N-Diisopropyltryptamine 27063:Tooltip N,N-Diisopropyltryptamine 25276:Desmetramadol (desmethyltramadol) 24604:Desmetramadol (desmethyltramadol) 23557:Dextropropoxyphene (propoxyphene) 23542:Desmetramadol (desmethyltramadol) 21188:Etybenzatropine (ethybenztropine) 18824:Tooltip Ligand gated ion channels 18398:Tooltip Epithelial sodium channel 13285:Dimethyltubocurarine (metocurine) 11832:Etybenzatropine (ethybenztropine) 11504:chlorphenamine (chlorpheniramine) 11488:Antihistamines (first-generation) 11265:Desmethylclozapine (norclozapine) 11117:Muscarinic acetylcholine receptor 11040: 10497:from the original on 19 June 2015 10413:from the original on 24 June 2021 10037:(Correspondence to Les Iverson ; 8330:(6): 1607–10, table of contents. 6169:from the original on 23 July 2021 6058:from the original on 9 March 2019 5155:Anesthesia: Essays and Researches 5123:10.1016/j.annemergmed.2014.06.018 5068:Current Opinion in Anesthesiology 4707:"Taming the ketamine tiger. 1965" 4232:10.1016/j.annemergmed.2010.11.030 3858:10.1016/j.jpainsymman.2011.01.001 3520: 3332:from the original on 8 April 2024 3306:from the original on 26 June 2020 1860:brain-derived neurotrophic factor 1166:is a combination of ketamine and 259: 153: 38844: 32349:Transform Drug Policy Foundation 32243:Other treaties addressing drugs 31723: 27734: 25656:Salvinorin B methoxymethyl ether 22660:Desmethylsibutramine (BTS-54354) 21936:Desmethylsibutramine (BTS-54354) 21366:Desmethylsibutramine (BTS-54354) 18462:Tooltip Acid-sensing ion channel 12641:Nicotinic acetylcholine receptor 10997: 10943: 10904: 10877: 10842: 10785: 10734: 10677: 10649:Revista de Investigacion Clinica 10636: 10606: 10575: 10510: 10478:from the original on 7 June 2015 10447:from the original on 7 June 2015 10386: 10345:. San Francisco: Panther Press. 10174: 10160:10.1097/00045391-200007060-00008 10148:American Journal of Therapeutics 10135:from the original on 5 May 2015. 10089:from the original on 9 June 2014 10068: 9993: 9961: 9748: 9599:10.1213/00000539-196601000-00007 9578: 9565: 9555: 9545: 9517: 9499:Anaesthesiologie und Reanimation 9241:10.1213/00000539-198202000-00004 8902:European Neuropsychopharmacology 8771:10.1097/00000542-199704000-00021 8619: 8498:10.1097/00000542-199803000-00029 8397:10.1097/00000542-200004000-00033 8337:10.1097/00000539-200212000-00025 8285:European Journal of Pharmacology 8020:10.1097/00000542-199901000-00023 7796:10.1016/j.neuropharm.2015.10.034 7535:Zanos P, Gould TD (April 2018). 7199:10.1097/00000542-199312000-00013 7150:10.1097/00000542-199503000-00005 7110:10.1111/j.1360-0443.2009.02761.x 6905:10.1111/j.1742-1241.2010.02502.x 6117:from the original on 2 July 2022 5956:Sanacora G, Katz R (July 2018). 5877:10.1001/jamapsychiatry.2017.0080 5358:Wong DH, Jenkins LC (May 1975). 4576:from the original on 16 May 2022 4368:10.1111/j.1360-0443.2011.03576.x 3911:10.1097/00004311-197412020-00018 2878: 2863: 1870:(mTOR) pathway, deactivation of 1467:(for serial ketamine injections) 887: 884: 878: 45: 36: 38972:Drug-facilitated sexual assault 33182:Regulation of therapeutic goods 33106:Fetal alcohol spectrum disorder 32667:Opium production in Afghanistan 25651:Salvinorin B ethoxymethyl ether 23271:Monoamine metabolism modulators 20566:Rislenemdaz (CERC-301, MK-0657) 19513:Negative allosteric modulators: 19401:Positive allosteric modulators: 19224:Negative allosteric modulators: 18977:Positive allosteric modulators: 15761:Monoamine metabolism modulators 13665:Meclofenoxate (centrophenoxine) 12990:Suxethonium (succinyldicholine) 12985:Suxamethonium (succinylcholine) 12553:Meclofenoxate (centrophenoxine) 12371:northiaden (desmethyldosulepin) 10343:The Essential Psychedelic Guide 10292:. Rockport, MA: Para Research. 10000:Sumitra DR (30 December 2013). 9941:"Status of ketamine under CDSA" 9634:Frontiers in Human Neuroscience 8914:10.1016/j.euroneuro.2015.07.021 8807:British Journal of Pharmacology 8528:Zhao Y, Sun L (November 2008). 8148:10.1016/j.euroneuro.2011.08.002 7040: 6989: 6940: 6484: 6379: 6129: 5757: 5548: 5450:Goyal S, Agrawal A (May 2013). 5392: 5351: 5308: 5267: 5236: 4874: 4588: 4026: 3942:Drug Metabolism and Disposition 3933: 3025: 3021:Ketamine in society and culture 2396: 2383:Tooltip Estrogen receptor alpha 2142: 2112: 2074: 1874:(GSK-3), and inhibition of the 1707: 1668: 1208:. In particular, children with 1119: 1013:Key:YQEZLKZALYSWHR-UHFFFAOYSA-N 296: 38668:positive allosteric modulators 33130:of tobacco or other substances 29065:Aspirin (acetylsalicylic acid) 27365:Tooltip N,N-Dipropyltryptamine 27073:Tooltip N,N-Dipropyltryptamine 26773:Pentoxyverine (carbetapentane) 25576:Norbuprenorphine-3-glucuronide 19802:Tooltip Dehydroepiandrosterone 19110:Tulrampator (S-47445, CX-1632) 19005:Farampator (CX-691, ORG-24448) 16280:Ziconotide (ω-conotoxin MVIIA) 12010:N-Methyl-3-piperidyl benzilate 10911:Riviere JE, Papich MG (2009). 10370:Ketamine: Dreams and Realities 10290:Journeys Into the Bright World 9896:. 12 June 2014. Archived from 9854:Poisons Standard October 2015 9058:Archives of General Psychiatry 8717:British Journal of Anaesthesia 8595:10.1523/JNEUROSCI.3481-08.2009 7065:10.1080/08998280.2014.11929117 6610:10.1002/14651858.CD009293.pub2 6320:Ketamine: Dreams and Realities 6261:10.1002/14651858.CD011611.pub3 6209:10.1002/14651858.CD011612.pub3 3433: 3394:10.1002/14651858.CD003351.pub3 3366: 3345: 3318: 2983:, a professor of chemistry at 2962:)‑(−)‑ketamine hydrochloride. 2649:receptors, Moreover, whereas D 2640:group found ketamine to be a D 2623:dopaminergic neurotransmission 1880:eukaryotic elongation factor 2 1330:treatment-resistant depression 1296:treatment-resistant depression 1274:complex regional pain syndrome 1083:treatment-resistant depression 890: 872: 285: 272: 1: 33162:Needle and syringe programmes 33111:Long-term effects of cannabis 32512:Psilocybin mushrooms legality 32439:School district drug policies 27714:Receptor/signaling modulators 26610:Dehydroepiandrosterone (DHEA) 25551:Nalodeine (N-allylnorcodeine) 24744:Met-enkephalin (metenkefalin) 24353:Nalodeine (N-allylnorcodeine) 23782:Met-enkephalin (metenkefalin) 23251:Receptor/signaling modulators 22325:Tooltip Serotonin transporter 20949:Monoamine reuptake inhibitors 20892:Receptor/signaling modulators 20741:Unknown/unsorted antagonists: 19305:Unknown/unsorted antagonists: 18898:Ionotropic glutamate receptor 18853:Receptor/signaling modulators 16255:Leconotide (ω-conotoxin CVID) 15743:Monoamine reuptake inhibitors 15716:Receptor/signaling modulators 13895:Adrogolide (ABT-431, DAS-431) 13701:Receptor/signaling modulators 13355:Hexamethonium (benzohexonium) 12589:Receptor/signaling modulators 12005:N-Ethyl-3-piperidyl benzilate 11022:10.1016/S0742-8413(00)00155-9 10582:Grinspoon P (9 August 2022). 10517:Bowman E (15 December 2023). 9800:10.1080/13543784.2017.1267727 9726:10.1016/s0006-3223(99)00230-9 9527:Journal of Separation Science 9137:Journal of Psychopharmacology 9110:10.1016/S0893-133X(00)00194-9 8867:10.1080/13651501.2016.1254802 7285:10.1016/s0952-8180(99)00131-2 6665:10.1016/S0140-6736(10)61462-6 6026:10.1016/S2215-0366(17)30102-5 5678:BioMed Research International 5606:Journal of Paramedic Practice 5037:10.1016/S0893-133X(01)00346-3 4271:10.1080/14737175.2019.1554434 4043:10.1016/S0099-5428(08)60347-0 3611:"Ketamine: use in anesthesia" 3250: 3165:, ketamine has been used for 2950:)‑(+)‑ketamine. However, its 2938:form. The free base form of ( 2584:monoamine reuptake inhibition 2531:ionotropic glutamate receptor 1868:mammalian target of rapamycin 1864:tropomyosin receptor kinase B 1580:, resulting in damage of the 1452:Severe liver disease such as 1279: 1124: 1104:and was extensively used for 281:(Other controlled substances) 38647:Dopamine reuptake inhibitors 38000:dopamine reuptake inhibitors 32232:1971 Psychotropic Substances 30308:Monoamine oxidase inhibitors 24774:N-Phenethyl-14-ethoxymetopon 22165:Tetracyclic antidepressants: 20962:Tooltip Dopamine transporter 12445:cyamemazine (cyamepromazine) 10438:(online), 23 July 2014, see 10075:Dixon H (12 February 2014). 9755:Chaffrey J (16 March 2022). 9439:Journal of Organic Chemistry 9359:. CRC Press. pp. 127–. 8690:10.1021/acschemneuro.7b00074 8297:10.1016/j.ejphar.2006.04.026 7966:10.1371/journal.pone.0059334 7603:10.1016/j.neuron.2018.05.032 7469:10.1016/j.ejphar.2012.11.023 7417:10.1016/j.drudis.2018.02.006 6401:10.1016/j.concog.2019.01.011 5524:10.1097/AAP.0000000000000806 5293:10.1001/archsurg.136.10.1118 5214:10.1097/EJA.0000000000000638 5111:Annals of Emergency Medicine 5080:10.1097/ACO.0000000000000916 4938:10.1586/17476348.2014.915752 4724:10.1097/ALN.0b013e3181ed09a2 4705:Domino EF (September 2010). 4667:10.1097/AAP.0000000000000808 4319:10.1021/acschemneuro.9b00493 4219:Annals of Emergency Medicine 4004:10.1097/ALN.0000000000001392 3793:10.1007/978-3-540-74806-9_15 3673:Hashimoto K (October 2019). 2965: 2854: 2811: 2806: 2443:Tooltip Dopamine transporter 1363:Food and Drug Administration 1345:randomized controlled trials 1286:Esketamine § Depression 7: 38799:Orexin receptor antagonists 37480:Misc. designer cannabinoids 33020:Pharmaceutical distribution 32657:Coca production in Colombia 32108:Counterculture of the 1960s 30502:Tooltip Monoamine oxidase B 30442:Tooltip Monoamine oxidase A 30071:tetracyclic antidepressants 28707:Paracetamol (acetaminophen) 26798:Racemethorphan (methorphan) 26427:β-Lipotropin (proendorphin) 26055:((pF)Phe)Nociceptin(1-13)NH 25436:Leumorphin (dynorphin B-29) 23922:Oxymorphone phenylhydrazone 22615:3,3-Diphenylcyclobutanamine 21891:3,3-Diphenylcyclobutanamine 20590:NR2A-selective antagonists: 20122:Polyamine site antagonists: 19347:Acromelic acid (acromelate) 18933:Acromelic acid (acromelate) 13435:Methorphan (racemethorphan) 12765:Bephenium hydroxynaphthoate 12259:Tetracyclic antidepressants 12150:Profenamine (ethopropazine) 11772:Dicycloverine (dicyclomine) 10251:The Little Book of Ketamine 9356:Opioid-Induced Hyperalgesia 8583:The Journal of Neuroscience 7898:10.1021/acs.orglett.7b02177 6459:10.3390/biomedicines9050470 6389:Consciousness and Cognition 5974:10.1176/appi.focus.20180012 5637:Academic Emergency Medicine 5618:10.12968/jpar.2011.3.10.552 5561:Academic Emergency Medicine 5243:Nickson C (7 August 2013). 4525:10.1176/appi.focus.20190048 3361:10.1007/978-981-15-2902-3_1 3172: 2946:and is therefore labelled ( 2607:monoamine oxidase inhibitor 1734:. Esketamine is a far more 1384: 1290:Ketamine is a rapid-acting 1251:opioid-induced hyperalgesia 1179:clinical practice guideline 10: 38998: 38615:Dopamine receptor agonists 33192:Substance abuse prevention 33167:Opioid replacement therapy 29979:Dextromethorphan/bupropion 26447:Proopiomelanocortin (POMC) 26067:-NH)Gly)Nociceptin(1-13)NH 25171:Adrenorphin (metorphamide) 24338:Methylsamidorphan chloride 23572:Dimethylaminopivalophenone 23397:Adrenorphin (metorphamide) 23255:Monoamine releasing agents 22813:Tricyclic antidepressants: 22089:Tricyclic antidepressants: 21158:Benzatropine (benztropine) 19030:Hydrochlorothiazide (HCTZ) 17816:Antiarrhythmics (class I): 15752:Monoamine releasing agents 14940:Flupentixol (flupenthixol) 14116:Flupentixol (flupenthixol) 12815:Dimethylphenylpiperazinium 12408:Tripitamine (tripitramine) 11632:Benzatropine (benztropine) 10863:10.1016/j.cvsm.2008.06.002 10810:10.1016/j.jfms.2003.10.002 10760:10.1186/s13071-020-04402-w 9628:Li L, Vlisides PE (2016). 9031:The Role of Brain Dopamine 8546:10.1016/j.jocn.2007.11.007 8180:Kapur S, Seeman P (2002). 6721:10.1016/j.ajem.2007.12.005 5829:10.1016/j.pain.2004.09.036 4763:. WHO/MHP/HPS/EML/2021.02. 3094: 3018: 2974: 2899:derivative. Ketamine is a 2653:receptor agonists such as 1872:glycogen synthase kinase 3 1866:(TrkB), activation of the 1800:alpha-7 nicotinic receptor 1536:Urinary and liver toxicity 1389:Ketamine is used to treat 1283: 862:Chemical and physical data 527:Intramuscular: 0.5–2 hours 72:CI-581; CL-369; CM-52372-2 18: 38942:Drugs developed by Pfizer 38927:NMDA receptor antagonists 38812: 38769:NMDA receptor antagonists 38625:Dopamine releasing agents 38502: 38421: 38393: 38192: 38098: 38038: 37904: 37478: 37147: 37086: 37040: 36799: 36790: 36762: 36742: 36735: 36470: 36350: 36312: 36281: 36253: 36223: 36127: 36061:2-Fluorodeschloroketamine 36053: 36042: 36021: 35942: 35847: 35805: 35768: 35712: 35675: 35529: 35492: 35450: 35413: 35372: 35363: 35335: 35195: 35164: 35038: 34967: 34938: 34857: 34803: 34759: 34667: 34589: 34429: 34326: 34248: 34175: 34107: 34029: 33951: 33923: 33907: 33555: 33375: 33322: 33301: 33205: 33197:Supervised injection site 33139: 33054: 32680: 32647: 32636: 32632: 32626: 32621: 32525: 32487:Anabolic steroid legality 32474: 32359: 32267: 32252:Convention Against Doping 32247:Law of the Sea Convention 32214: 32210: 32199: 32178:Urban legends about drugs 32090: 32042: 31979: 31876: 31843: 31735: 31731: 31718: 31655: 31628: 31566: 31512: 31413: 31318: 31309: 31254: 31087: 30950: 30815: 30811: 30800: 30760: 30702: 30637: 30626: 30543: 30530: 30492: 30432: 30318: 30314: 30301: 30277: 30239: 30081: 30077: 30060: 29961: 29933: 29900: 29867: 29834: 29801: 29753: 29695: 29691: 29673: 29591: 29510: 29467: 29445: 29408:Tricyclic antidepressants 29364: 29316: 29305: 29267: 29222: 29171: 29055: 29022: 28971: 28907: 28871: 28781: 28772: 28681: 28479: 28297: 28238: 28229: 28143: 28118: 28090: 28057: 27998: 27965: 27917: 27889: 27880: 27787: 27742: 27707: 27433: 27156: 26509: 26367:Racecadotril (acetorphan) 26315: 26227: 26042: 26031: 25774:Buprenorphine/samidorphan 25731: 25686:Tricyclic antidepressants 25128: 25117: 24897: 24764:Mitragynine pseudoindoxyl 24471: 24460: 24117: 23807:Mitragynine pseudoindoxyl 23326: 23243: 23199: 23068: 22879: 22808: 22607: 22531: 22345: 22318: 22196: 22160: 22084: 21883: 21807: 21721: 21635: 21608: 21291: 21145: 21109: 21033: 20982: 20955: 20883: 19972:Glycine site antagonists: 19558: 19316: 18907: 18846: 18817: 18792: 18785: 18719: 18712: 18665: 18637: 18623: 18601: 18538: 18524: 18515: 18469: 18455: 18433: 18405: 18391: 18334: 18326:Tricyclic antidepressants 17796: 17782: 17773: 17747: 17714: 17700: 17644: 17612: 17595: 17476: 17335:Glibenclamide (glyburide) 17296: 17282: 17245: 16808: 16794: 16785: 16753: 15843: 15820: 15706: 15604:Metitepine (methiothepin) 15030:Pericyazine (periciazine) 14828: 14454:Dihydrexidine derivatives 14333: 14320: 14293:Metitepine (methiothepin) 14089: 14059: 13881:Dihydrexidine derivatives 13781: 13768: 13693: 13607: 13068: 12664: 12650: 12581: 12495: 12311:Tricyclic antidepressants 11861:+beclometasone/formoterol 11438:3-Quinuclidinyl benzilate 11428: 11140: 11126: 11083: 11065: 10549:"Do you know... Ketamine" 10395:"The Ketamine Necromance" 10118:. Rules and Regulations. 8678:ACS Chemical Neuroscience 8640:10.1016/j.bcp.2020.114210 8445:10.1016/j.bcp.2018.03.032 8103:10.1007/s00213-010-1834-7 8091:Psychopharmacology (Berl) 7841:10.1016/j.nbd.2016.07.010 7694:10.1007/s40263-018-0492-x 7367:10.1007/s40262-016-0383-6 6814:10.36076/ppj.2010/13/E343 6764:10.1016/j.jad.2019.11.028 6558:10.1007/s40263-018-0569-6 6357:10.1007/s11910-019-0983-2 5927:10.1007/s40263-018-0519-3 5783:10.1186/s12871-019-0910-8 4991:10.1001/archpsyc.57.3.270 4815:. StatPearls Publishing. 4747:World Health Organization 4609:10.1007/s40262-016-0383-6 4597:Clinical Pharmacokinetics 4513:Focus (Am Psychiatr Publ) 4419:10.1016/j.jad.2020.09.007 4306:ACS Chemical Neuroscience 3561:Kintz P (22 March 2014). 3084:Controlled Substances Act 2841:Alpha-ketol rearrangement 2601:and at least three human 2518: 2024:Tooltip κ-Opioid receptor 1995:Tooltip μ-Opioid receptor 1963:Tooltip μ-Opioid receptor 1809:mesolimbic reward pathway 1760:NMDA receptor antagonists 1629:gastrointestinal diseases 1396: 1361:In February 2022, the US 1349:major depressive disorder 1334:Esketamine and Depression 1326:European Medicines Agency 1021: 996: 976: 966: 931: 909: 896: 866: 861: 842: 810: 790: 770: 742: 722: 702: 682: 662: 637: 591: 567: 562: 539: 519: 499: 473: 447: 418: 408: 355: 347: 249: 244: 219: 206:dissociative hallucinogen 191: 179: 167: 141: 94: 76: 68: 58: 53: 44: 35: 38887:2-Chlorophenyl compounds 32993:Turks and Caicos Islands 32502:Methamphetamine legality 31815:Marijuana Policy Project 30806:Major recreational drugs 30685:Rubidium chloride (RbCl) 28742:+propyphenazone/caffeine 26675:Fabomotizole (afobazole) 26650:Dimethyltryptamine (DMT) 26352:Dexecadotril (retorphan) 26324:Enkephalinase inhibitors 26253:BTRX-246040 (LY-2940094) 26235:(Nphe)Nociceptin(1-13)NH 26151:Nociceptin (orphanin FQ) 22539:Atomoxetine (tomoxetine) 21815:Atomoxetine (tomoxetine) 19860:Competitive antagonists: 19768:Polyamine site agonists: 19754:Neboglamine (nebostinel) 19323:Tooltip Kainate receptor 15206:Clotiapine (clothiapine) 15080:Spiperone (spiroperidol) 15045:Piflutixol (pifluthixol) 13675:Phosphatidylethanolamine 12563:Phosphatidylethanolamine 10643:Pérez-Esparza R (2018). 9647:10.3389/fnhum.2016.00612 9587:Anesthesia and Analgesia 9149:10.1177/0269881107077767 8628:Biochemical Pharmacology 8433:Biochemical Pharmacology 8136:Eur Neuropsychopharmacol 6095:10.1177/0004867419883341 5742:10.36076/ppj.2011/14/145 5469:10.4103/0972-5229.117048 5168:10.4103/0259-1162.143110 4473:10.1177/0706743720970860 1677:the sedative effects of 1643:Dependence and tolerance 1347:in adults with unipolar 1255:postanesthetic shivering 988:Clc1ccccc1C2(NC)CCCCC2=O 972:92 °C (198 °F) 198:NMDA receptor antagonist 36007:substituted benzofurans 35819:(Mipracetin) 4-AcO-MiPT 35432:(Daltacetin) 4-AcO-DALT 31770:Cannabis rights leaders 30548:Atypical antipsychotics 27639:Mepyramine (pyrilamine) 27320:3-Methoxydextrallorphan 26980:3-Methoxydextrallorphan 26803:Racemorphan (morphanol) 26050:(Arg14,Lys15)Nociceptin 25321:Dynorphin B (rimorphin) 24363:Nalorphine dinicotinate 22917:mepyramine (pyrilamine) 20842:Pentamidine isethionate 20586:Traxoprodil (CP-101606) 19825:Epipregnanolone sulfate 17939:Eslicarbazepine acetate 15162:Atypical antipsychotics 14545:Atypical antipsychotics 14478:N,N-Propyldihydrexidine 14178:Atypical antipsychotics 14067:Tetrahydroisoquinolines 13455:Morphanol (racemorphan) 13395:Laudexium (laudolissin) 12805:Desformylflustrabromine 11787:Diphemanil metilsulfate 11642:Benzilylcholine mustard 11589:Atypical antipsychotics 10747:Parasites & Vectors 10710:10.1126/science.1190287 10507:, accessed 7 June 2015. 10457:, accessed 7 June 2015. 10047:Open Government Licence 9353:Mao J (19 April 2016). 9097:Neuropsychopharmacology 8248:10.1124/jpet.116.235838 7829:Neurobiology of Disease 7309:Andrade C (July 2017). 7235:Neuropsychopharmacology 6137:"Spravato (esketamine)" 5024:Neuropsychopharmacology 3355:. Springer, Singapore. 2850:Preparation of ketamine 1234: 1214:neuromuscular disorders 1040:dissociative anesthetic 530:Insufflation: 45–60 min 487:Subcutaneous: 15–30 min 38922:Muscarinic antagonists 38733:nACh receptor agonists 38116:Aliphatic hydrocarbons 35689:(Depracetin) 4-AcO-DPT 35506:(Ipracetin) 4-AcO-DiPT 32578:Politics of drug abuse 31546:Mandragora officinarum 28592:Pethidine (meperidine) 27694:Tiospirone (BMY-13859) 27634:Gevotroline (WY-47384) 27559:18-Methoxycoronaridine 27546:Allosteric modulators: 27305:Panamesine (EMD-57455) 27255:Siramesine (Lu 28-179) 27192:Ditolylguanidine (DTG) 26955:Allosteric modulators: 26918:Panamesine (EMD-57455) 26863:BMY-14802 (BMS-181100) 26655:Ditolylguanidine (DTG) 26635:Dextromethorphan (DXM) 25666:Spiradoline (U-62,066) 25611:Pethidine (meperidine) 24804:Pethidine (meperidine) 24494:ADL-5747 (PF-04856881) 24140:4-Caffeoyl-1,5-quinide 24039:Tetrahydropapaveroline 23954:Pethidine (meperidine) 23191:Vanoxerine (GBR-12909) 23038:pethidine (meperidine) 22293:pethidine (meperidine) 21081:Pethidine (meperidine) 20872:Allosteric modulators: 20807:Ipenoxazone (MLV-6976) 20462:Pethidine (meperidine) 20083:Licostinel (ACEA-1021) 20005:Apimostinel (NRX-1074) 19669:Apimostinel (NRX-1074) 19637:Glycine site agonists: 19469:Licostinel (ACEA-1021) 19180:Licostinel (ACEA-1021) 19065:Mibampator (LY-451395) 17683:Rottlerin (mallotoxin) 15814:Ion channel modulators 14836:Typical antipsychotics 14097:Typical antipsychotics 12433:Typical antipsychotics 12205:Scopolamine (hyoscine) 11880:Hexahydrosiladifenidol 11857:Glycopyrronium bromide 11074:Acetylcholine receptor 10559:. 2003. Archived from 10397:. In Parfrey A (ed.). 9497:Krüger AD (1998). "". 9200:10.1093/bja/51.12.1167 7248:10.1038/sj.npp.1300994 6497:Acta Médica Portuguesa 6014:The Lancet. Psychiatry 3847:(Therapeutic Review). 3075:, it became labeled a 3066:Drug and Cosmetics Act 3056:In December 2013, the 2985:Wayne State University 2958:and is thus labelled ( 2851: 2749: 2739:plasma protein binding 2730:approximately 25–50%. 2572:monoamine transporters 1633:hepatobiliary disorder 1491:to hallucinations and 1484: 1470:Age less than 3 months 1465:substance use disorder 1423:cardiovascular disease 1379:near-death experiences 1210:cyanotic heart disease 490:Insufflation: 5–10 min 484:Intramuscular: 1–5 min 38932:Nicotinic antagonists 38819:Recreational drug use 38755:Nitric oxide prodrugs 38143:Aromatic hydrocarbons 35870:(Lucigenol) 4-HO-MPMI 35787:(Metocetin) 4-AcO-MET 35667:(Psilocybin) 4-PO-DMT 35464:(Ethacetin) 4-AcO-DET 32938:Saint Kitts and Nevis 32237:1988 Drug Trafficking 31830:Cannabis and religion 30794:Recreational drug use 29213:+paracetamol/caffeine 29191:Metamizole (dipyrone) 29125:Morpholine salicylate 29069:+paracetamol/caffeine 26965:Methylphenylpiracetam 26540:Alazocine (SKF-10047) 26357:Ecadotril (sinorphan) 25844:CERC-501 (LY-2456302) 25744:4',7-Dihydroxyflavone 25306:Dinalbuphine sebacate 25181:Alazocine (SKF-10047) 24905:4',7-Dihydroxyflavone 24864:Thiobromadol (C-8813) 24504:Alazocine (SKF-10047) 24150:4',7-Dihydroxyflavone 24130:2-(S)-N,N-(R)-Viminol 23602:Dinalbuphine sebacate 23275:Monoamine neurotoxins 22841:Dosulepin (dothiepin) 22388:Didesmethylcitalopram 22117:Dosulepin (dothiepin) 21794:Serdexmethylphenidate 21096:Serdexmethylphenidate 20541:CO-101244 (PD-174494) 20257:Delucemine (NPS-1506) 20207:Alazocine (SKF-10047) 16040:Ryodipine (riodipine) 15770:Monoamine neurotoxins 14564:Aripiprazole lauroxil 13660:Glycerophosphocholine 12548:Glycerophosphocholine 12351:dosulepin (dothiepin) 12155:Propantheline bromide 12030:Otenzepad (AF-DX 116) 11584:Atropine methonitrate 10662:10.24875/RIC.18002501 10399:Apocalypse Culture II 9460:US patent 3254124 8199:10.1038/sj.mp.4001093 8056:10.1007/s005400050035 8044:Journal of Anesthesia 7015:10.2147/IMCRJ.S100648 6965:10.3892/etm.2017.4913 6083:Aust N Z J Psychiatry 4895:10.1007/s001010050510 4177:10.1124/pr.117.015198 3210:veterinary anesthesia 3147:Apocalypse Culture II 2849: 2747: 1744:central sensitization 1574:eosinophilic cystitis 1482: 1429:or poorly controlled 1373:Near-death experience 1320:commercially sold as 1202:neuromuscular blocker 513:Norketamine: 12 hours 510:Ketamine: 2.5–3 hours 38892:D2-receptor agonists 38877:Arylcyclohexylamines 36079:(N-Ethylnorketamine) 35824:(Miprocin) 4-HO-MiPT 35647:(Bufotenin) 5-HO-DMT 35484:(Ethocybin) 4-PO-DET 35427:(Daltocin) 4-HO-DALT 35086:Cyclopropylmescaline 33187:Responsible drug use 32998:United Arab Emirates 32317:Drug Policy Alliance 32205:Legality of drug use 31810:Legality of cannabis 31785:Cannabis Social Club 31755:Cannabis cultivation 31750:Cannabis consumption 31581:Cannabis (Marijuana) 31403:Psilocybin mushrooms 30669:Hypericum perforatum 30537:Adjunctive therapies 29336:Gabapentin enacarbil 29130:Potassium salicylate 29120:Magnesium salicylate 29115:Imidazole salicylate 28942:Indometacin farnesil 28338:Diamorphine (heroin) 28305:Acetyldihydrocodeine 28092:Neuroactive steroids 28059:Arylcyclohexylamines 26788:Pregnenolone sulfate 26600:Cutamesine (SA-4503) 26214:Sunobinop (S-117957) 25949:N-Fluoropropyl-JDTic 25281:Diamorphine (heroin) 24614:Diamorphine (heroin) 23582:Diamorphine (heroin) 23382:Acetyldihydrocodeine 23362:7-Hydroxymitragynine 23357:7-Acetoxymitragynine 23166:Methoxytetrabenazine 23131:Dihydrotetrabenazine 22945:Arylcyclohexylamines 22240:Arylcyclohexylamines 21391:Dizocilpine (MK-801) 21345:Chaenomeles speciosa 21046:Benocyclidine (BTCP) 20561:Radiprodil (RGH-896) 20536:Buphenine (nylidrin) 20113:Rapastinel (GLYX-13) 19928:Midafotel (d-CPPene) 19835:Pregnenolone sulfate 19759:Rapastinel (GLYX-13) 19550:Pregnenolone sulfate 19291:Pregnenolone sulfate 18029:Valproate semisodium 16560:Carboxyamidotriazole 16495:Gabapentin enacarbil 16475:Arbaclofen placarbil 15539:Desmethoxyfallypride 14750:Propylnorapomorphine 14549:Alentemol (U-66444B) 14021:Propylnorapomorphine 13655:Dimethylethanolamine 13520:Rapacuronium bromide 13500:Pipecuronium bromide 13340:Gantacurium chloride 13300:Dizocilpine (MK-801) 12885:MEM-63,908 (RG-3487) 12835:Ethoxysebacylcholine 12543:Dimethylethanolamine 12463:Umeclidinium bromide 12343:desmethyldesipramine 12060:Oxyphenonium bromide 11270:Ethoxysebacylcholine 10409:. pp. 288–295. 10181:Giannini AJ (1999). 10028:(12 February 2014), 9900:on 22 November 2013. 9894:Government of Canada 9890:Justice Laws Website 9533:(15–17): 1155–1166. 9464:Parke Davis & Co 9331:10.1093/bja/53.7.778 9290:10.1093/bja/57.2.197 8730:10.1093/bja/77.4.441 8186:Molecular Psychiatry 7541:Molecular Psychiatry 7405:Drug Discovery Today 7328:10.4088/JCP.17f11802 5418:10.7759/cureus.27065 5249:Life in the Fastlane 4775:"Ketamine Injection" 3954:10.1124/dmd.30.7.853 3899:Int Anesthesiol Clin 3727:Eur J Clin Pharmacol 3302:. 22 November 2019. 3079:on 12 February 2014. 3032:controlled substance 2942:)‑ketamine exhibits 2819:is reacted with the 2817:2-chlorobenzonitrile 1792:)-hydroxynorketamine 1601:pentosan polysulfate 1262:spinal sensitization 533:By mouth: 1–6+ hours 481:Intravenous: seconds 38962:Veterinary medicine 38912:General anesthetics 38494:Drugs which induce 38177:Chlorofluorocarbons 35993:in general (e. g.: 35875:(Meprocin) 4-HO-MPT 35694:(Deprocin) 4-HO-DPT 35662:(Psilocin) 4-HO-DMT 35511:(Iprocin) 4-HO-DiPT 35213:2C-B-DragonFLY-NBOH 34747:N-(2C-TFM) fentanyl 34742:N-(2C-T-7) fentanyl 34737:N-(2C-T-4) fentanyl 34732:N-(2C-T-2) fentanyl 34430:Atypical structures 33452:Dimethyllysergamide 33427:3-Pentyllysergamide 33245:Tobacco consumption 33215:Alcohol consumption 33157:Drug rehabilitation 33094:Effects of cannabis 32818:Indian Ocean region 32598:Philippine drug war 32227:1961 Narcotic Drugs 30908:nail polish remover 29685:receptor modulators 29681:reuptake inhibitors 29085:Carbasalate calcium 27776:General anesthetics 26938:Rimcazole (BW-234U) 26417:Ubenimex (bestatin) 26161:Nociceptin (1-13)NH 25769:β-Chlornaltrexamine 25739:4′-Hydroxyflavanone 25161:β-Chlornaltrexamine 25035:N-Benzylnaltrindole 24930:β-Chlornaltrexamine 24849:TAN-67 (SB-205,607) 24514:AR-M100390 (ARM390) 24175:β-Chlornaltrexamine 24145:4′-Hydroxyflavanone 23372:α-Chlornaltrexamine 22790:Threohydrobupropion 22655:Desmethylsertraline 22383:Desmethylcitalopram 22066:Threohydrobupropion 21931:Desmethylsertraline 21586:Threohydrobupropion 21361:Desmethylsertraline 19792:-Hydroxycholesterol 19603:Homoquinolinic acid 19576:Main site agonists: 19334:Main site agonists: 18928:5-Fluorowillardiine 18925:Main site agonists: 18680:1,10-Phenanthroline 17237:Spooky toxin (SsTx) 16222:Tetrahydropalmatine 15679:Tetrahydropalmatine 14412:Dihydroergocryptine 14051:Tetrahydropalmatine 13854:Dihydroergocryptine 13670:Phosphatidylcholine 13555:Threohydrobupropion 13540:Stercuronium iodide 13475:Pancuronium bromide 12558:Phosphatidylcholine 12220:Sofpironium bromide 12105:Pipenzolate bromide 11915:Ipratropium bromide 11717:Cimetropium bromide 11047:Ketamine fact sheet 10702:2010Sci...329..959L 10082:The Daily Telegraph 9689:. 29 October 2013. 9452:10.1021/jo01020a019 9390:Br J Clin Pharmacol 7957:2013PLoSO...859334R 7743:10.1093/ijnp/pyy041 7647:10.1038/nature25509 7639:2018Natur.554..317Y 7553:10.1038/mp.2017.255 6649:(9752): 1558–1565. 5691:10.1155/2015/749837 5512:Reg Anesth Pain Med 5280:Archives of Surgery 4978:Arch Gen Psychiatry 4655:Reg Anesth Pain Med 4558:"Ketamine toxicity" 3204:Veterinary medicine 3188:Ketamine has shown 3058:government of India 3034:in many countries. 3015:Society and culture 2897:arylcyclohexylamine 2707:cerebrospinal fluid 2627:indirect/downstream 2619:hypertensive crisis 1900: 1832:receptor antagonism 1718:Mechanism of action 1637:acute kidney injury 1206:tracheal intubation 1193:who are at risk of 1139:circulatory systems 1106:surgical anesthesia 1102:veterinary medicine 493:By mouth: 15–30 min 32: 38967:Equine medications 38897:Dissociative drugs 38696:nonbenzodiazepines 38403:Calea zacatechichi 37998:agonists, such as 37588:ADAMANTYL-THPINACA 35782:(Metocin) 4-HO-MET 35568:4-Propionyloxy-DMT 35469:(Ethocin) 4-HO-DET 35218:2C-B-FLY-NB2EtO5Cl 35156:Trifluoromescaline 35039:Mescaline (subst.) 34712:N-(2C-IP) fentanyl 33447:Diallyllysergamide 33422:2-Butyllysergamide 33101:Drug-related crime 32778:Dominican Republic 32688:Illegal drug trade 32163:Religion and drugs 32118:Drug paraphernalia 32098:Chasing the dragon 32057:Fashion cigarettes 31638:Calea zacatechichi 31333:Psychoactive toads 31043:Mitragyna speciosa 30995:Dextropropoxyphene 30937:Nonbenzodiazepines 30845:Alcoholic beverage 30729:Never to phase III 29618:Never to phase III 29523:Analgesic adjuvant 29424:1.7/1.8-selective: 29090:Choline salicylate 28517:Dextropropoxyphene 28170:Never to phase III 26695:Igmesine (JO-1784) 26624:prasterone sulfate 25979:Norbinaltorphimine 25286:Diacetylnalorphine 24975:Diacetylnalorphine 24599:Desmethylclozapine 24253:Diacetylnalorphine 23933:Papaver somniferum 23517:Chloroxymorphamine 23030:dextropropoxyphene 21056:Dexmethylphenidate 20140:Diethylenetriamine 19819:prasterone sulfate 19594:Homocysteic acid ( 19337:5-Bromowillardiine 18690:7,8-Benzoquinoline 18685:4,7-Phenanthroline 18675:1,7-Phenanthroline 18051:Local anesthetics: 17583:ML-297 (VU0456810) 17090:Diallyl trisulfide 17085:Dextropropoxyphene 16988:Tetraethylammonium 16695:Pinaverium bromide 16465:4-Methylpregabalin 13590:Vecuronium bromide 13530:Rocuronium bromide 13440:Methyllycaconitine 13365:Hydroxynorketamine 13260:Dextropropoxyphene 13245:Dehydronorketamine 13235:Dacuronium bromide 12291:Tiotropium bromide 12286:Timepidium bromide 12045:Oxitropium bromide 12000:Muscarinic toxin 7 11875:Hexahydrodifenidol 11822:Emepronium bromide 11473:Ambutonium bromide 11448:Aclidinium bromide 10857:(6): 1187–203, v. 10620:. 13 August 2019. 10553:Knowledge Exchange 10393:Woodard D (2000). 10007:The Times of India 9977:. 7 January 2014. 9974:The Times of India 9857:"Poisons Standard" 7355:Clin Pharmacokinet 5770:BMC Anesthesiology 5650:10.1111/acem.13502 5574:10.1111/acem.12604 5377:10.1007/BF03004843 5255:on 9 February 2014 5202:Eur J Anaesthesiol 4100:10.1002/ibra.12094 3785:Modern Anesthetics 3739:10.1007/BF00607095 3103:dissociative state 2852: 2785:dehydronorketamine 2781:hydroxynorketamine 2750: 2668:prolactin levels. 2615:serotonin syndrome 1894: 1844:signaling pathways 1828:hydroxynorketamine 1780:4-chlorokynurenine 1554:frequent urination 1493:emergence delirium 1485: 1446:Poorly controlled 1417:for ketamine are: 1391:status epilepticus 1356:bipolar depression 1187:emergency medicine 1054:. Ketamine is an 521:Duration of action 466:Hydroxynorketamine 461:Dehydronorketamine 340:In general Rx-only 202:general anesthetic 28: 38937:Opioid modulators 38832: 38831: 38826: 38825: 38684:ethanol (alcohol) 38507:μ-Opioid receptor 38461: 38460: 38457: 38456: 38109: 38031: 37900: 37899: 37896: 37895: 36756: 36485: 36466: 36465: 36282:Diarylethylamines 36249: 36248: 36072:Deschloroketamine 36036: 36017: 36016: 36010: 35938: 35937: 35834:(Moxy) 5-MeO-MiPT 35377:-alkyltryptamines 35331: 35330: 35151:Trifluoroescaline 35136:Methallylescaline 35091:Difluoromescaline 34755: 34754: 34727:N-(2C-T) fentanyl 34722:N-(2C-P) fentanyl 34717:N-(2C-N) fentanyl 34707:N-(2C-I) fentanyl 34702:N-(2C-H) fentanyl 34697:N-(2C-G) fentanyl 34692:N-(2C-E) fentanyl 34687:N-(2C-D) fentanyl 34682:N-(2C-C) fentanyl 34677:N-(2C-B) fentanyl 34585: 34584: 33522:Methylergometrine 33316: 33261: 33260: 33257: 33256: 33253: 33252: 33172:Pharmacovigilance 33152:Drug legalization 33050: 33049: 32617: 32616: 32613: 32612: 32548:Cognitive liberty 32492:Cannabis legality 32280:Decriminalization 32195: 32194: 32191: 32190: 32077:Smoking fetishism 31714: 31713: 31710: 31709: 31651: 31650: 31531:Atropa belladonna 30898:contact adhesives 30840:Ethanol (alcohol) 30754:Recreational uses 30745: 30744: 30739: 30738: 30698: 30697: 30671:(St. John's Wort) 30622: 30621: 30587:lithium carbonate 30526: 30525: 30522: 30521: 30297: 30296: 30293: 30292: 30106:Amitriptylinoxide 30056: 30055: 30052: 30051: 29628: 29627: 29463: 29462: 29447:Potassium openers 29384:Local anesthetics 29326:Alcohol (ethanol) 29263: 29262: 29162:methyl salicylate 29150:Sodium salicylate 29037:Meclofenamic acid 28712:+aspirin/caffeine 28677: 28676: 28180: 28179: 28139: 28138: 27957:Thiotetrabarbital 27862:Trichloroethylene 27727: 27726: 27721: 27720: 27556:Unknown/unsorted: 27317:Unknown/unsorted: 27052: 26977:Unknown/unsorted: 26640:Dextrorphan (DXO) 26466: 26465: 26311: 26310: 26156:Nociceptin (1-11) 26027: 26026: 25156:14-Methoxymetopon 25113: 25112: 25030:Methylnaltrindole 24456: 24455: 24125:(3S,4S)-Picenadol 23737:Levacetylmethadol 23283: 23282: 23278: 23064: 23063: 22339: 22314: 22313: 21759:Levophacetoperane 21629: 21604: 21603: 21466:Levophacetoperane 21041:4-Fluoropethidine 20976: 20915: 20914: 20766: 20722:Trichloroethylene 20667:Ethanol (alcohol) 20032: 19975:4-Cl-KYN (AV-101) 19743: 19735: 19702: 19694: 19686: 19643: 19628:Tetrazolylglycine 19597: 19535:Ethanol (alcohol) 19524:sodium thiopental 19342:5-Iodowillardiine 19251:Ethanol (alcohol) 19235:sodium thiopental 18864: 18863: 18842: 18841: 18781: 18780: 18777: 18776: 18739:Meclofenamic acid 18708: 18707: 18619: 18618: 18511: 18510: 18507: 18506: 18451: 18450: 18387: 18386: 18261:RG7893 (GDC-0287) 18024:Valproate pivoxil 17914:Acetylpheneturide 17769: 17768: 17765: 17764: 17696: 17695: 17668:Meclofenamic acid 17631:Ethanol (alcohol) 17591: 17590: 17540:Minoxidil sulfate 17278: 17277: 16781: 16780: 16777: 16776: 16680:Otilonium bromide 16605:Ethanol (alcohol) 16369:ω-Conotoxin MVIIC 16105:Phenylalkylamines 15780: 15779: 15773: 15764: 15755: 15746: 15737: 15728: 15719: 15702: 15701: 15609:N-Methylspiperone 15467:Trimethobenzamide 14527: 14519: 14511: 14316: 14315: 13974: 13966: 13953: 13759:Dopamine receptor 13725: 13724: 13719: 13718: 13680:Phosphorylcholine 13618: 13603: 13602: 13400:Levacetylmethadol 13280:Dihydrochandonium 13160:sodium thiopental 12830:Ethanol (alcohol) 12607: 12606: 12568:Phosphorylcholine 12506: 12491: 12490: 12428:Trospium chloride 12323:amitriptylinoxide 12296:Tiquizium bromide 12140:Prifinium bromide 12035:Otilonium bromide 11990:Methylscopolamine 11985:Methylhomatropine 11842:Fentonium bromide 11722:Clidinium bromide 11006:Lymnaea stagnalis 10924:978-1-118-68590-7 10696:(5994): 959–964. 10379:978-0-9660019-3-8 10368:Jansen K (2001). 10352:978-0-9642636-1-1 10330:978-0-89281-757-3 10299:978-0-914918-12-7 10276:978-1-57951-121-0 10241:978-0-914171-72-0 10200:978-1-885987-11-2 9841:978-3-88763-075-1 9402:10.1111/bcp.12614 9366:978-1-4200-8900-4 9041:978-3-642-73897-5 9000:10.1002/syn.20647 8957:10.1002/syn.20561 8819:10.1111/bph.13222 7892:(17): 4572–4575. 7835:(Pt B): 119–126. 7784:Neuropharmacology 7633:(7692): 317–322. 7411:(10): 1689–1692. 6857:10.1002/nau.24341 6795:Smith HS (2010). 6510:10.20344/amp.9679 6329:978-0-9660019-3-8 6318:Jansen K (2001). 5643:(10): 1086–1097. 3802:978-3-540-72813-9 3691:10.1111/pcn.12902 3627:10.1111/cns.12072 3615:CNS Neurosci Ther 3574:978-0-12-416969-2 3533:MedicinesComplete 3509:978-3-319-42925-0 3326:"Drug Scheduling" 3277:978-94-011-4439-1 3107:depersonalization 2981:Calvin L. Stevens 2789:first-pass effect 2564:on the receptor. 2523: 2522: 1890:Molecular targets 1848:neurotransmission 1415:contraindications 1409:Contraindications 1305:suicidal thoughts 1268:experienced with 1266:wind-up phenomena 1131:muscle relaxation 1033: 1032: 922:Interactive image 812:CompTox Dashboard 337: Unscheduled 336: 324: 312: 299: 288: 276: 268:(Controlled drug) 263: 157: 124: 107: 38989: 38849: 38848: 38847: 38840: 38488: 38481: 38474: 38465: 38464: 38103: 38073:Amanita muscaria 38012:releasing agents 37993: 36797: 36796: 36777:THC (Dronabinol) 36760: 36759: 36747: 36740: 36739: 36687:Phenyltoloxamine 36475: 36327:Dextromethorphan 36054:Ketamine-related 36051: 36050: 36040: 36039: 36026: 35988: 35812: 35775: 35713:Ibogaine-related 35682: 35536: 35499: 35457: 35420: 35370: 35369: 35106:Fluoroproscaline 35096:Difluoroescaline 35046:2-Bromomescaline 34334: 34256: 34183: 34115: 34037: 33959: 33931: 33921: 33920: 33905: 33904: 33564: 33563: 33320: 33319: 33306: 33288: 33281: 33274: 33265: 33264: 33089:Drug harmfulness 33084:Driving impaired 32903:Papua New Guinea 32672:Rolling meth lab 32645: 32644: 32634: 32633: 32623: 32622: 32588:Mexican drug war 32497:Cocaine legality 32482:Alcohol legality 32312:Demand reduction 32300:Supply reduction 32212: 32211: 32201: 32200: 31878:Drinking culture 31820:Medical cannabis 31780:Cannabis smoking 31737:Cannabis culture 31733: 31732: 31720: 31719: 31696:recreational use 31541:Hyoscyamus niger 31502:Salvia divinorum 31485:Amanita muscaria 31447:recreational use 31427:recreational use 31316: 31315: 30884:recreational use 30813: 30812: 30802: 30801: 30787: 30780: 30773: 30764: 30763: 30749: 30748: 30679: 30645: 30628: 30627: 30601:triiodothyronine 30597:Thyroid hormones 30532: 30531: 30503: 30499: 30443: 30439: 30384:Phenoxypropazine 30316: 30315: 30303: 30302: 30247: 30243: 30089: 30085: 30079: 30078: 30062: 30061: 29941: 29937: 29908: 29904: 29875: 29871: 29842: 29838: 29809: 29805: 29761: 29757: 29703: 29699: 29693: 29692: 29675: 29674: 29655: 29648: 29641: 29632: 29631: 29318:Calcium blockers 29314: 29313: 29210: 29159: 28985: 28973:COX-2 inhibitors 28939: 28858:Tiaprofenic acid 28829: 28816: 28808: 28779: 28778: 28656: 28436: 28375: 28347: 28319: 28236: 28235: 28207: 28200: 28193: 28184: 28183: 27887: 27886: 27769: 27762: 27755: 27746: 27745: 27731: 27730: 27411: 27407: 27366: 27362: 27356: 27352: 27225:(midomafetamine) 27224: 27074: 27070: 27064: 27060: 27050: 26718:(midomafetamine) 26717: 26586: 26582: 26493: 26486: 26479: 26470: 26469: 26346: 26273:Nociceptin (1-7) 26169:Norbuprenorphine 26106:Dihydroetorphine 26040: 26039: 25929:Methylnaltrexone 25839:Catechin gallate 25571:Norbuprenorphine 25296:Dihydroetorphine 25166:β-Funaltrexamine 25126: 25125: 25025:Methylnaltrexone 24965:Catechin gallate 24779:Norbuprenorphine 24619:Dihydroetorphine 24469: 24468: 24333:Methylnaltrexone 24225:Catechin gallate 24180:β-Funaltrexamine 23592:Dihydroetorphine 23335: 23334: 23310: 23303: 23296: 23287: 23286: 23245: 23232:Antagonist-like: 23126:Deutetrabenazine 23076: 23072: 23016:MIN-117 (WF-516) 22981:Dextromethorphan 22353:6-Nitroquipazine 22343: 22342: 22337: 22333: 22328: 22326: 22322: 21749:Hydroxybupropion 21633: 21632: 21627: 21623: 21618: 21616: 21612: 21506:MIN-117 (WF-516) 21446:Hydroxybupropion 21386:Diphenylpyraline 21117:Diphenylprolinol 20980: 20979: 20974: 20970: 20965: 20963: 20959: 20942: 20935: 20928: 20919: 20918: 20764: 20717:Trichloroethanol 20277:Dextromethorphan 20030: 19814: 19803: 19799: 19741: 19733: 19700: 19692: 19684: 19641: 19595: 19566: 19562: 19324: 19320: 19155:Fanapanel (MPQX) 18915: 18911: 18891: 18884: 18877: 18868: 18867: 18825: 18821: 18800: 18796: 18790: 18789: 18717: 18716: 18635: 18634: 18631: 18627: 18536: 18535: 18532: 18528: 18522: 18521: 18467: 18466: 18463: 18459: 18403: 18402: 18399: 18395: 18014:Sodium valproate 17929:Chlorphenacemide 17911:Anticonvulsants: 17794: 17793: 17790: 17786: 17780: 17779: 17729:Arachidonic acid 17712: 17711: 17708: 17704: 17610: 17609: 17606: 17602: 17579: 17575: 17496: 17492: 17448:Dextromethorphan 17424: 17420: 17316: 17312: 17294: 17293: 17290: 17286: 16806: 16805: 16802: 16798: 16792: 16791: 16764:L-type-selective 16575:Dimeditiapramine 16537:Others/unsorted: 16319:T-type-selective 16306:R-type-selective 16288:P-type-selective 16240:ω-Conotoxin GVIA 16230:N-type-selective 15860:Dihydropyridines 15854:L-type-selective 15841: 15840: 15837: 15833: 15827: 15826: 15807: 15800: 15793: 15784: 15783: 15767: 15758: 15749: 15740: 15731: 15722: 15710: 15589:Levofenfluramine 15457:Thiethylperazine 15134:+tranylcypromine 15065:Prochlorperazine 14880:Chlorproethazine 14525: 14517: 14512:-DOPA (levodopa) 14509: 14331: 14330: 14165:+tranylcypromine 13972: 13964: 13954:-DOPA (levodopa) 13951: 13779: 13778: 13752: 13745: 13738: 13729: 13728: 13612: 13550:Thiocolchicoside 13360:Hydroxybupropion 13255:Dextromethorphan 13127:Allopregnanolone 13081: 13077: 12980:Suberyldicholine 12690:6-Chloronicotine 12677: 12673: 12662: 12661: 12658: 12654: 12634: 12627: 12620: 12611: 12610: 12500: 12281:Tiemonium iodide 12236: 12232: 12100:Phenyltoloxamine 12055:Oxyphencyclimine 11556:phenyltoloxamine 11360:Suberyldicholine 11138: 11137: 11134: 11130: 11110: 11103: 11096: 11087: 11086: 11069: 11068: 11059:Pharmacodynamics 11054: 11053: 11034: 11033: 11001: 10995: 10994: 10974: 10968: 10967: 10966: 10964: 10959:on 4 August 2013 10947: 10941: 10940: 10938: 10936: 10908: 10902: 10901: 10881: 10875: 10874: 10846: 10840: 10839: 10821: 10789: 10783: 10782: 10772: 10762: 10738: 10732: 10731: 10721: 10681: 10675: 10674: 10664: 10640: 10634: 10633: 10631: 10629: 10610: 10604: 10603: 10601: 10599: 10579: 10573: 10572: 10570: 10568: 10545: 10539: 10538: 10536: 10534: 10514: 10508: 10506: 10504: 10502: 10487: 10485: 10483: 10464: 10458: 10456: 10454: 10452: 10443:. 23 July 2014. 10432: 10423: 10422: 10420: 10418: 10390: 10384: 10383: 10365: 10359: 10356: 10334: 10317:Inner Traditions 10303: 10280: 10249:Kelly K (2001). 10245: 10226:. Berkeley, CA: 10211: 10205: 10204: 10188: 10178: 10172: 10171: 10143: 10137: 10136: 10134: 10128:(133): 37673–5. 10121:Federal Register 10117: 10111:(13 July 1999). 10105: 10099: 10098: 10096: 10094: 10072: 10066: 10065: 10063: 10061: 10055: 10036: 10022: 10016: 10015: 9997: 9991: 9990: 9988: 9986: 9965: 9959: 9956: 9954: 9952: 9936: 9934: 9932: 9927:on 8 August 2014 9926: 9910: 9901: 9879: 9873: 9872: 9870: 9868: 9852: 9846: 9845: 9826: 9820: 9819: 9783: 9777: 9776: 9774: 9772: 9752: 9746: 9745: 9709: 9703: 9702: 9700: 9698: 9679: 9670: 9669: 9659: 9649: 9625: 9619: 9618: 9582: 9576: 9569: 9563: 9559: 9553: 9549: 9543: 9542: 9521: 9515: 9514: 9494: 9488: 9485: 9484: 9480: 9472: 9471: 9467: 9455: 9430: 9424: 9423: 9413: 9381: 9375: 9374: 9350: 9344: 9343: 9333: 9309: 9303: 9302: 9292: 9268: 9262: 9261: 9243: 9219: 9213: 9212: 9202: 9178: 9169: 9168: 9132: 9123: 9122: 9112: 9088: 9082: 9081: 9052: 9046: 9045: 9026: 9020: 9019: 8983: 8977: 8976: 8940: 8934: 8933: 8896: 8887: 8886: 8850: 8841: 8840: 8830: 8798: 8792: 8791: 8773: 8749: 8743: 8742: 8732: 8708: 8702: 8701: 8684:(6): 1122–1134. 8673: 8660: 8659: 8623: 8617: 8616: 8606: 8574: 8568: 8567: 8557: 8525: 8519: 8518: 8500: 8476: 8467: 8466: 8456: 8424: 8418: 8417: 8399: 8375: 8358: 8357: 8339: 8315: 8309: 8308: 8279: 8270: 8269: 8259: 8227: 8212: 8211: 8201: 8177: 8168: 8167: 8131: 8125: 8124: 8114: 8082: 8076: 8075: 8039: 8033: 8032: 8022: 7998: 7989: 7988: 7978: 7968: 7933: 7920: 7919: 7909: 7877: 7871: 7870: 7852: 7824: 7818: 7817: 7807: 7771: 7765: 7764: 7754: 7722: 7716: 7715: 7705: 7673: 7667: 7666: 7622: 7616: 7615: 7605: 7581: 7575: 7574: 7564: 7532: 7517: 7516: 7514: 7512: 7497: 7491: 7490: 7480: 7448: 7439: 7438: 7428: 7396: 7387: 7386: 7350: 7341: 7340: 7330: 7321:(7): e858–e861. 7306: 7297: 7296: 7267: 7261: 7260: 7250: 7226: 7220: 7219: 7201: 7177: 7171: 7170: 7152: 7128: 7122: 7121: 7093: 7087: 7086: 7076: 7044: 7038: 7037: 7027: 7017: 6993: 6987: 6986: 6976: 6959:(4): 2757–2762. 6944: 6938: 6937: 6935: 6933: 6907: 6883: 6877: 6876: 6851:(4): 1049–1062. 6845:Neurourol Urodyn 6840: 6827: 6826: 6816: 6792: 6786: 6785: 6775: 6743: 6737: 6736: 6700: 6685: 6684: 6658: 6638: 6632: 6631: 6621: 6604:(11): CD009293. 6589: 6578: 6577: 6552:(11): 997–1009. 6541: 6535: 6534: 6532: 6530: 6512: 6488: 6482: 6481: 6471: 6461: 6437: 6431: 6430: 6412: 6383: 6377: 6376: 6340: 6334: 6333: 6315: 6309: 6308: 6306: 6304: 6289: 6283: 6282: 6272: 6255:(10): CD011611. 6240: 6231: 6230: 6220: 6203:(11): CD011612. 6188: 6179: 6178: 6176: 6174: 6159: 6153: 6152: 6150: 6148: 6133: 6127: 6126: 6124: 6122: 6074: 6068: 6067: 6065: 6063: 6037: 6005: 5996: 5995: 5985: 5953: 5947: 5946: 5910: 5897: 5896: 5860: 5849: 5848: 5812: 5806: 5805: 5795: 5785: 5761: 5755: 5754: 5744: 5720: 5714: 5713: 5703: 5693: 5669: 5663: 5662: 5652: 5628: 5622: 5621: 5601: 5595: 5594: 5576: 5552: 5546: 5545: 5535: 5503: 5492: 5491: 5481: 5471: 5447: 5441: 5440: 5430: 5420: 5396: 5390: 5389: 5379: 5355: 5349: 5348: 5312: 5306: 5305: 5295: 5271: 5265: 5264: 5262: 5260: 5240: 5234: 5233: 5197: 5191: 5190: 5180: 5170: 5146: 5135: 5134: 5106: 5100: 5099: 5063: 5050: 5049: 5039: 5015: 5004: 5003: 4993: 4969: 4958: 4957: 4921: 4915: 4914: 4883:Der Anaesthesist 4878: 4872: 4871: 4843: 4837: 4836: 4834: 4832: 4806: 4797: 4796: 4794: 4792: 4771: 4765: 4764: 4762: 4743: 4737: 4736: 4726: 4702: 4689: 4688: 4678: 4646: 4629: 4628: 4592: 4586: 4585: 4583: 4581: 4553: 4547: 4546: 4536: 4504: 4495: 4494: 4484: 4461:Can J Psychiatry 4452: 4439: 4438: 4401: 4388: 4387: 4351: 4340: 4339: 4321: 4297: 4291: 4290: 4254: 4245: 4244: 4234: 4210: 4199: 4198: 4188: 4156: 4139: 4138: 4120: 4102: 4078: 4057: 4056: 4030: 4024: 4023: 3998:(6): 1103–1112. 3987: 3974: 3973: 3937: 3931: 3930: 3894: 3883: 3882: 3880: 3878: 3860: 3836: 3815: 3814: 3780: 3759: 3758: 3722: 3713: 3712: 3702: 3670: 3649: 3648: 3638: 3606: 3583: 3582: 3558: 3549: 3548: 3546: 3544: 3524: 3518: 3517: 3493: 3458: 3457: 3437: 3431: 3430: 3428: 3426: 3420: 3405: 3379: 3370: 3364: 3349: 3343: 3341: 3339: 3337: 3322: 3316: 3315: 3313: 3311: 3292: 3286: 3285: 3261: 3091:Recreational use 3044:Poisons Standard 2928:optical rotation 2921:enantiopure drug 2882: 2867: 2821:Grignard reagent 2779:and CYP2B6 into 2713:Pharmacokinetics 2580:allosteric sites 2473: 2469: 2444: 2440: 2415: 2411: 2398: 2384: 2380: 2204: 2200: 2168: 2164: 2144: 2114: 2076: 2025: 2021: 1996: 1992: 1964: 1960: 1935: 1931: 1901: 1893: 1805:lateral habenula 1713:Pharmacodynamics 1615:is also useful. 1593:anticholinergics 1582:epithelial cells 1162:administration. 1029: 1028: 924: 904: 892: 889: 886: 880: 874: 857: 846: 835: 834: 820: 818: 803: 783: 763: 755: 735: 715: 695: 675: 655: 645: 644: 630: 604: 504: 334: 331: 322: 319: 310: 307: 298: 295: 287: 284: 274: 271: 261: 258: 236: 155: 152: 134: 123: 120: 117: 106: 103: 90: 49: 40: 33: 31: 27: 38997: 38996: 38992: 38991: 38990: 38988: 38987: 38986: 38872:Antidepressants 38857: 38856: 38855: 38845: 38843: 38835: 38833: 38828: 38827: 38822: 38808: 38688:alcoholic drink 38676:benzodiazepines 38664: 38655:methylphenidate 38633:methamphetamine 38593: 38547: 38498: 38492: 38462: 38453: 38417: 38408:Silene capensis 38389: 38188: 38102: 38094: 38045: 38043: 38034: 38020:methamphetamine 38008:methylphenidate 37997: 37994:Also indirect D 37992: 37909: 37892: 37863:THC-O-phosphate 37528:5F-CUMYL-PINACA 37474: 37143: 37082: 37036: 36786: 36753: 36746: 36731: 36712:Trihexyphenidyl 36607:Diphenhydramine 36522:Brompheniramine 36480: 36474: 36462: 36346: 36308: 36304:Methoxphenidine 36277: 36245: 36219: 36123: 36104:Methoxyketamine 36045: 36031: 36025: 36013: 35987: 35934: 35843: 35801: 35764: 35708: 35704:(The Light) DPT 35671: 35614:5-MeO-α,N,N-TMT 35525: 35488: 35446: 35409: 35359: 35327: 35191: 35160: 35034: 34963: 34934: 34853: 34799: 34751: 34669:N-(2C)-fentanyl 34663: 34581: 34572:NBOMe-mescaline 34425: 34322: 34244: 34171: 34103: 34025: 33947: 33903: 33558: 33551: 33378: 33371: 33352:Bromo-DragonFLY 33314: 33312: 33305: 33297: 33292: 33262: 33249: 33207: 33201: 33177:Reagent testing 33135: 33126:Passive smoking 33056: 33046: 32676: 32662:Drug precursors 32649: 32640: 32638: 32628: 32609: 32563:Drug possession 32538:Cannabis rights 32521: 32517:Salvia legality 32470: 32361: 32355: 32263: 32206: 32187: 32168:Self-medication 32086: 32082:Tobacco smoking 32044:Smoking culture 32038: 31975: 31872: 31839: 31795:Cannabis vaping 31765:Cannabis rights 31760:Cannabis edible 31727: 31706: 31647: 31643:Silene capensis 31624: 31562: 31558:Diphenhydramine 31508: 31409: 31305: 31250: 31202:Methylphenidate 31192:Methamphetamine 31083: 30946: 30830:Benzodiazepines 30807: 30796: 30791: 30756: 30746: 30741: 30740: 30735: 30734: 30719:Clinical trials 30694: 30633: 30618: 30614: 30606: 30591:lithium citrate 30539: 30518: 30501: 30498: 30488: 30441: 30438: 30428: 30404:Tranylcypromine 30310: 30289: 30273: 30245: 30235: 30087: 30073: 30048: 29957: 29939: 29929: 29906: 29896: 29873: 29863: 29840: 29830: 29807: 29797: 29778:Levomilnacipran 29759: 29749: 29701: 29687: 29669: 29662:Antidepressants 29659: 29629: 29624: 29623: 29608:Clinical trials 29587: 29568:Phenazopyridine 29506: 29487:Cyclobenzaprine 29459: 29441: 29423: 29366:Sodium blockers 29360: 29308: 29301: 29259: 29218: 29208: 29167: 29157: 29051: 29047:Tolfenamic acid 29032:Flufenamic acid 29018: 28983: 28967: 28937: 28903: 28867: 28827: 28814: 28806: 28768: 28732:+metoclopramide 28673: 28654: 28475: 28434: 28373: 28356:Dihydromorphine 28345: 28317: 28293: 28225: 28211: 28181: 28176: 28175: 28160:Clinical trials 28135: 28114: 28086: 28053: 27994: 27967:Benzodiazepines 27961: 27913: 27876: 27783: 27773: 27738: 27728: 27723: 27722: 27717: 27703: 27623:St. John's wort 27449:Ethylketazocine 27429: 27409: 27364: 27354: 27230:Methamphetamine 27161: 27152: 27138:Trifluoperazine 27072: 27062: 26738:Methylphenidate 26728:Methamphetamine 26584: 26514: 26505: 26497: 26467: 26462: 26344: 26307: 26238: 26223: 26164: 26086: 26078: 26070: 26066: 26058: 26035: 26023: 25819:Binaltorphimine 25764:6β-Naltrexol-d4 25727: 25346:Ethylketazocine 25301:Dihydromorphine 25121: 25109: 24920:6β-Naltrexol-d4 24893: 24649:Ethylketazocine 24624:Dihydromorphine 24464: 24452: 24160:6β-Naltrexol-d4 24113: 23912:Oxymorphonazine 23667:Furanylfentanyl 23597:Dihydromorphine 23452:Benzhydrocodone 23341: 23339: 23330: 23322: 23317:Opioid receptor 23314: 23284: 23279: 23239: 23217:DAT modulators: 23195: 23096:methamphetamine 23074: 23060: 22971:Cyclobenzaprine 22913:diphenhydramine 22901:brompheniramine 22875: 22804: 22603: 22569:Levomilnacipran 22527: 22335: 22327: 22324: 22310: 22208:brompheniramine 22192: 22156: 22080: 21879: 21840:Levomilnacipran 21803: 21774:Methylphenidate 21717: 21625: 21617: 21614: 21600: 21287: 21141: 21105: 21076:Methylphenidate 21051:Desoxypipradrol 21029: 20972: 20964: 20961: 20951: 20946: 20916: 20911: 20879: 20777:Flufenamic acid 20712:Trichloroethane 20487:Rhynchophylline 20407:Methoxphenidine 20372:Levomilnacipran 20272:Dextromethadone 20197:α-Endopsychosin 19801: 19713:Dimethylglycine 19623:Quinolinic acid 19564: 19554: 19392:Quisqualic acid 19322: 19312: 18968:Quisqualic acid 18913: 18903: 18895: 18865: 18860: 18838: 18823: 18813: 18798: 18773: 18769:Trifluoperazine 18764:Tolfenamic acid 18734:Flufenamic acid 18704: 18661: 18629: 18615: 18597: 18563:Flufenamic acid 18558:Ethacrynic acid 18530: 18503: 18461: 18447: 18429: 18397: 18383: 18330: 18161:Metabutoxycaine 18126:Diphenhydramine 18116:Cyclomethycaine 18081:Levobupivacaine 17788: 17761: 17743: 17706: 17692: 17688:Tolfenamic acid 17663:Flufenamic acid 17658: 17640: 17626: 17604: 17601: 17587: 17577: 17494: 17491: 17472: 17422: 17314: 17311: 17288: 17274: 17259: 17241: 17221: 17130:Norpropoxyphene 17007:11.1)-specific: 17006: 16800: 16773: 16749: 16705:Rhynchophylline 16455: 15835: 15816: 15811: 15781: 15776: 15698: 15474:Antidepressants 15140:Triflupromazine 15130:Trifluoperazine 15110:Thioproperazine 14890:Chlorprothixene 14824: 14485:Phenethylamines 14325: 14312: 14161:Trifluoperazine 14111:Chlorprothixene 14085: 14055: 13922:Phenethylamines 13773: 13764: 13756: 13726: 13721: 13720: 13715: 13689: 13611: 13599: 13205:Chlorisondamine 13079: 13072: 13064: 12675: 12668: 12656: 12646: 12638: 12608: 12603: 12577: 12499: 12487: 12441:chlorprothixene 12398:Trihexyphenidyl 12234: 12215:Silahexacyclium 12095:Phenglutarimide 11757:Desfesoterodine 11737:Cyclobenzaprine 11528:diphenhydramine 11492:brompheniramine 11424: 11375:Thiopilocarpine 11132: 11122: 11114: 11079: 11061: 11043: 11038: 11037: 11002: 10998: 10975: 10971: 10962: 10960: 10949: 10948: 10944: 10934: 10932: 10925: 10909: 10905: 10882: 10878: 10847: 10843: 10790: 10786: 10739: 10735: 10682: 10678: 10641: 10637: 10627: 10625: 10612: 10611: 10607: 10597: 10595: 10580: 10576: 10566: 10564: 10563:on 7 April 2014 10547: 10546: 10542: 10532: 10530: 10515: 10511: 10500: 10498: 10489: 10481: 10479: 10466: 10465: 10461: 10450: 10448: 10439: 10433: 10426: 10416: 10414: 10391: 10387: 10380: 10366: 10362: 10353: 10331: 10300: 10284:Alltounian HS, 10277: 10242: 10212: 10208: 10201: 10179: 10175: 10144: 10140: 10132: 10115: 10106: 10102: 10092: 10090: 10073: 10069: 10059: 10057: 10053: 10043:Crown copyright 10034: 10023: 10019: 9998: 9994: 9984: 9982: 9967: 9966: 9962: 9950: 9948: 9939: 9930: 9928: 9924: 9908: 9904: 9884: 9880: 9876: 9866: 9864: 9855: 9853: 9849: 9842: 9828: 9827: 9823: 9784: 9780: 9770: 9768: 9761:NBC Connecticut 9753: 9749: 9714:Biol Psychiatry 9710: 9706: 9696: 9694: 9681: 9680: 9673: 9626: 9622: 9583: 9579: 9570: 9566: 9560: 9556: 9550: 9546: 9522: 9518: 9495: 9491: 9482: 9469: 9431: 9427: 9382: 9378: 9367: 9351: 9347: 9310: 9306: 9269: 9265: 9220: 9216: 9193:(12): 1167–73. 9179: 9172: 9133: 9126: 9089: 9085: 9053: 9049: 9042: 9028: 9027: 9023: 8984: 8980: 8941: 8937: 8897: 8890: 8851: 8844: 8813:(17): 4254–76. 8799: 8795: 8750: 8746: 8709: 8705: 8674: 8663: 8624: 8620: 8575: 8571: 8534:J Clin Neurosci 8526: 8522: 8477: 8470: 8425: 8421: 8376: 8361: 8316: 8312: 8280: 8273: 8228: 8215: 8178: 8171: 8132: 8128: 8083: 8079: 8040: 8036: 7999: 7992: 7934: 7923: 7886:Organic Letters 7878: 7874: 7825: 7821: 7772: 7768: 7723: 7719: 7674: 7670: 7623: 7619: 7582: 7578: 7533: 7520: 7510: 7508: 7499: 7498: 7494: 7463:(1–3): 228–34. 7457:Eur J Pharmacol 7449: 7442: 7397: 7390: 7351: 7344: 7307: 7300: 7268: 7264: 7241:(8): 1793–800. 7227: 7223: 7178: 7174: 7129: 7125: 7094: 7090: 7045: 7041: 6994: 6990: 6945: 6941: 6931: 6929: 6884: 6880: 6841: 6830: 6793: 6789: 6752:J Affect Disord 6744: 6740: 6715:(9): 985–1028. 6701: 6688: 6656:10.1.1.690.1283 6639: 6635: 6590: 6581: 6542: 6538: 6528: 6526: 6503:(10): 598–605. 6489: 6485: 6438: 6434: 6384: 6380: 6341: 6337: 6330: 6316: 6312: 6302: 6300: 6291: 6290: 6286: 6241: 6234: 6189: 6182: 6172: 6170: 6161: 6160: 6156: 6146: 6144: 6135: 6134: 6130: 6120: 6118: 6075: 6071: 6061: 6059: 6006: 5999: 5954: 5950: 5911: 5900: 5865:JAMA Psychiatry 5861: 5852: 5813: 5809: 5762: 5758: 5721: 5717: 5670: 5666: 5629: 5625: 5612:(10): 552–556. 5602: 5598: 5553: 5549: 5504: 5495: 5448: 5444: 5397: 5393: 5356: 5352: 5313: 5309: 5286:(10): 1118–23. 5272: 5268: 5258: 5256: 5241: 5237: 5198: 5194: 5147: 5138: 5117:(1): 43–51.e2. 5107: 5103: 5064: 5053: 5016: 5007: 4970: 4961: 4922: 4918: 4879: 4875: 4844: 4840: 4830: 4828: 4807: 4800: 4790: 4788: 4773: 4772: 4768: 4744: 4740: 4703: 4692: 4647: 4632: 4593: 4589: 4579: 4577: 4554: 4550: 4505: 4498: 4453: 4442: 4407:J Affect Disord 4402: 4391: 4352: 4343: 4298: 4294: 4255: 4248: 4211: 4202: 4157: 4142: 4079: 4060: 4053: 4031: 4027: 3988: 3977: 3938: 3934: 3895: 3886: 3876: 3874: 3837: 3818: 3803: 3781: 3762: 3723: 3716: 3685:(10): 613–627. 3671: 3652: 3607: 3586: 3575: 3559: 3552: 3542: 3540: 3525: 3521: 3510: 3494: 3461: 3438: 3434: 3424: 3422: 3418: 3388:(9): CD003351. 3377: 3371: 3367: 3350: 3346: 3335: 3333: 3324: 3323: 3319: 3309: 3307: 3294: 3293: 3289: 3278: 3262: 3258: 3253: 3240:, or sometimes 3222:rodent cocktail 3206: 3183:neuroplasticity 3179:psychoplastogen 3175: 3099: 3093: 3086:in August 1999. 3046:(October 2015). 3028: 3023: 3017: 2997:human prisoners 2977: 2968: 2893: 2892: 2891: 2890: 2889: 2883: 2875: 2874: 2868: 2857: 2814: 2809: 2723:bioavailability 2715: 2697:psychotomimetic 2690: 2683: 2652: 2648: 2643: 2635: 2611:tranylcypromine 2591: 2577: 2562:allosteric site 2506: 2482: 2471: 2453: 2442: 2424: 2413: 2393: 2382: 2364: 2354: 2337: 2327: 2323: 2306: 2296: 2292: 2275: 2265: 2261: 2244: 2234: 2230: 2213: 2202: 2199: 2195: 2177: 2166: 2163: 2159: 2139: 2129: 2120: 2111: 2107: 2103: 2102: 2095: 2090: 2071: 2061: 2052: 2045: 2041: 2037: 2036: 2029: 2023: 2005: 1994: 1991: 1973: 1962: 1944: 1933: 1898: 1892: 1876:phosphorylation 1720: 1715: 1710: 1697:decrease them. 1671: 1645: 1613:botulinum toxin 1611:. Intravesical 1609:hyaluronic acid 1562:urinary urgency 1538: 1477: 1475:Adverse effects 1427:unstable angina 1411: 1399: 1387: 1375: 1341:Cochrane review 1288: 1282: 1237: 1191:traumatic shock 1156:benzodiazepines 1144:Psychotomimetic 1127: 1122: 1112:. It is on the 1079:bronchodilation 1077:, and moderate 1052:pain management 1024: 1022: 1017: 1014: 1009: 1004: 1003: 992: 989: 984: 983: 938:Racemic mixture 927: 902: 883: 877: 838: 814: 806: 786: 766: 738: 718: 698: 678: 658: 641: 633: 622: 587: 584: 575: 574: 502: 475:Onset of action 410:Protein binding 357:Bioavailability 349:Pharmacokinetic 343: 240: 182: 170: 163: 144: 137: 64:Ketalar, others 24: 17: 12: 11: 5: 38995: 38985: 38984: 38979: 38974: 38969: 38964: 38959: 38954: 38952:Sigma agonists 38949: 38944: 38939: 38934: 38929: 38924: 38919: 38914: 38909: 38904: 38899: 38894: 38889: 38884: 38879: 38874: 38869: 38854: 38853: 38830: 38829: 38824: 38823: 38813: 38810: 38809: 38807: 38806: 38796: 38766: 38759:alkyl nitrites 38752: 38730: 38716: 38710:sodium oxybate 38703: 38700:quinazolinones 38662: 38658: 38644: 38622: 38612: 38591: 38587: 38574: 38559:gabapentinoids 38545: 38541: 38503: 38500: 38499: 38491: 38490: 38483: 38476: 38468: 38459: 38458: 38455: 38454: 38452: 38451: 38446: 38441: 38436: 38431: 38425: 38423: 38419: 38418: 38416: 38415: 38410: 38405: 38399: 38397: 38391: 38390: 38388: 38387: 38382: 38377: 38372: 38367: 38362: 38357: 38352: 38350:Racemethorphan 38347: 38342: 38337: 38332: 38327: 38322: 38317: 38312: 38307: 38302: 38297: 38292: 38287: 38285:Levomethorphan 38282: 38277: 38272: 38267: 38262: 38257: 38252: 38247: 38242: 38237: 38232: 38227: 38222: 38217: 38212: 38207: 38201: 38199: 38190: 38189: 38187: 38186: 38185: 38184: 38179: 38169: 38168: 38167: 38162: 38152: 38151: 38150: 38140: 38139: 38138: 38133: 38128: 38123: 38112: 38110: 38096: 38095: 38093: 38092: 38087: 38082: 38077: 38065: 38060: 38055: 38049: 38047: 38041: 38036: 38035: 38033: 38032: 37995: 37987: 37982: 37977: 37972: 37967: 37965:Phenethylamine 37962: 37957: 37952: 37947: 37942: 37937: 37932: 37927: 37922: 37916: 37914: 37907: 37902: 37901: 37898: 37897: 37894: 37893: 37891: 37890: 37885: 37880: 37875: 37870: 37865: 37860: 37855: 37850: 37845: 37840: 37835: 37830: 37825: 37820: 37815: 37810: 37805: 37800: 37795: 37790: 37785: 37780: 37775: 37770: 37765: 37760: 37755: 37750: 37745: 37740: 37735: 37730: 37725: 37720: 37715: 37710: 37705: 37700: 37695: 37690: 37685: 37680: 37675: 37670: 37665: 37660: 37655: 37653:CUMYL-THPINACA 37650: 37645: 37640: 37635: 37630: 37625: 37620: 37615: 37610: 37605: 37600: 37595: 37590: 37585: 37580: 37575: 37570: 37565: 37560: 37555: 37550: 37545: 37540: 37535: 37530: 37525: 37520: 37515: 37510: 37505: 37500: 37495: 37490: 37484: 37482: 37476: 37475: 37473: 37472: 37467: 37462: 37457: 37452: 37447: 37442: 37437: 37432: 37427: 37422: 37417: 37412: 37407: 37402: 37397: 37392: 37387: 37382: 37377: 37372: 37367: 37362: 37357: 37352: 37347: 37342: 37337: 37332: 37327: 37322: 37317: 37312: 37307: 37302: 37297: 37292: 37287: 37282: 37277: 37272: 37267: 37262: 37257: 37252: 37247: 37242: 37237: 37232: 37227: 37222: 37217: 37212: 37207: 37202: 37197: 37192: 37187: 37182: 37177: 37172: 37167: 37162: 37156: 37154: 37145: 37144: 37142: 37141: 37136: 37131: 37126: 37121: 37116: 37111: 37106: 37101: 37095: 37093: 37084: 37083: 37081: 37080: 37075: 37070: 37065: 37060: 37055: 37049: 37047: 37038: 37037: 37035: 37034: 37029: 37024: 37019: 37014: 37009: 37004: 36999: 36994: 36989: 36984: 36979: 36974: 36969: 36964: 36959: 36954: 36949: 36944: 36939: 36934: 36929: 36924: 36919: 36914: 36909: 36904: 36899: 36894: 36889: 36884: 36879: 36874: 36869: 36864: 36859: 36854: 36849: 36844: 36839: 36834: 36829: 36824: 36819: 36814: 36808: 36806: 36794: 36788: 36787: 36785: 36784: 36779: 36774: 36768: 36766: 36757: 36751: 36737: 36733: 36732: 36730: 36729: 36724: 36719: 36717:Tripelennamine 36714: 36709: 36704: 36699: 36694: 36689: 36684: 36679: 36674: 36669: 36664: 36659: 36654: 36649: 36644: 36639: 36634: 36629: 36624: 36619: 36614: 36609: 36604: 36602:Dimenhydrinate 36599: 36594: 36592:Cyproheptadine 36589: 36584: 36579: 36574: 36572:Chlorphenamine 36569: 36567:Chloropyramine 36564: 36559: 36554: 36549: 36544: 36539: 36534: 36529: 36524: 36519: 36514: 36509: 36504: 36499: 36494: 36488: 36486: 36468: 36467: 36464: 36463: 36461: 36460: 36455: 36450: 36445: 36440: 36435: 36430: 36425: 36420: 36415: 36410: 36405: 36400: 36395: 36390: 36385: 36380: 36375: 36370: 36365: 36360: 36354: 36352: 36348: 36347: 36345: 36344: 36339: 36337:Racemethorphan 36334: 36329: 36324: 36322:Dextrallorphan 36318: 36316: 36310: 36309: 36307: 36306: 36301: 36296: 36291: 36285: 36283: 36279: 36278: 36276: 36275: 36270: 36265: 36259: 36257: 36251: 36250: 36247: 36246: 36244: 36243: 36238: 36233: 36227: 36225: 36221: 36220: 36218: 36217: 36211: 36205: 36199: 36194: 36188: 36185:Dieticyclidine 36182: 36177: 36172: 36167: 36162: 36157: 36152: 36147: 36142: 36137: 36131: 36129: 36125: 36124: 36122: 36121: 36116: 36111: 36106: 36101: 36099:Methoxmetamine 36096: 36091: 36086: 36085:((S)-ketamine) 36080: 36074: 36069: 36068:((R)-ketamine) 36063: 36057: 36055: 36048: 36037: 36019: 36018: 36015: 36014: 36012: 36011: 35982: 35977: 35972: 35967: 35962: 35957: 35952: 35946: 35944: 35940: 35939: 35936: 35935: 35933: 35932: 35927: 35922: 35917: 35912: 35907: 35902: 35897: 35892: 35887: 35882: 35877: 35872: 35867: 35862: 35857: 35851: 35849: 35845: 35844: 35842: 35841: 35836: 35831: 35826: 35821: 35815: 35813: 35803: 35802: 35800: 35799: 35794: 35789: 35784: 35778: 35776: 35766: 35765: 35763: 35762: 35757: 35752: 35747: 35742: 35737: 35732: 35727: 35722: 35716: 35714: 35710: 35709: 35707: 35706: 35701: 35696: 35691: 35685: 35683: 35673: 35672: 35670: 35669: 35664: 35659: 35654: 35649: 35644: 35639: 35634: 35621: 35616: 35611: 35598: 35585: 35580: 35575: 35570: 35565: 35560: 35558:4-HO-5-MeO-DMT 35555: 35550: 35545: 35539: 35537: 35527: 35526: 35524: 35523: 35518: 35513: 35508: 35502: 35500: 35490: 35489: 35487: 35486: 35481: 35476: 35471: 35466: 35460: 35458: 35448: 35447: 35445: 35444: 35439: 35434: 35429: 35423: 35421: 35411: 35410: 35408: 35407: 35402: 35397: 35392: 35387: 35381: 35379: 35367: 35361: 35360: 35358: 35357: 35352: 35347: 35341: 35339: 35333: 35332: 35329: 35328: 35326: 35325: 35320: 35315: 35310: 35305: 35300: 35295: 35290: 35285: 35280: 35275: 35270: 35265: 35260: 35255: 35250: 35245: 35240: 35235: 35230: 35225: 35220: 35215: 35210: 35208:2C-B-DragonFLY 35205: 35203:2C-B-BUTTERFLY 35199: 35197: 35193: 35192: 35190: 35189: 35186: 35183: 35180: 35177: 35174: 35170: 35168: 35162: 35161: 35159: 35158: 35153: 35148: 35146:Thioproscaline 35143: 35138: 35133: 35128: 35123: 35118: 35113: 35108: 35103: 35098: 35093: 35088: 35083: 35078: 35073: 35068: 35063: 35058: 35053: 35048: 35042: 35040: 35036: 35035: 35033: 35032: 35027: 35022: 35017: 35012: 35007: 35002: 34997: 34992: 34987: 34982: 34976: 34974: 34972: 34965: 34964: 34962: 34961: 34956: 34951: 34945: 34943: 34936: 34935: 34933: 34932: 34927: 34922: 34917: 34912: 34907: 34902: 34897: 34892: 34887: 34882: 34877: 34872: 34866: 34864: 34855: 34854: 34852: 34851: 34846: 34841: 34836: 34831: 34826: 34821: 34816: 34810: 34808: 34801: 34800: 34798: 34797: 34792: 34787: 34782: 34777: 34772: 34766: 34764: 34757: 34756: 34753: 34752: 34750: 34749: 34744: 34739: 34734: 34729: 34724: 34719: 34714: 34709: 34704: 34699: 34694: 34689: 34684: 34679: 34673: 34671: 34665: 34664: 34662: 34661: 34656: 34651: 34646: 34641: 34636: 34631: 34626: 34621: 34616: 34611: 34606: 34600: 34598: 34587: 34586: 34583: 34582: 34580: 34579: 34574: 34569: 34567:NBOMe-escaline 34564: 34559: 34554: 34549: 34544: 34539: 34534: 34529: 34524: 34519: 34514: 34509: 34504: 34499: 34494: 34489: 34484: 34479: 34474: 34469: 34464: 34459: 34454: 34449: 34444: 34439: 34433: 34431: 34427: 34426: 34424: 34423: 34418: 34413: 34408: 34403: 34398: 34393: 34388: 34383: 34378: 34373: 34368: 34363: 34358: 34353: 34348: 34343: 34337: 34335: 34324: 34323: 34321: 34320: 34315: 34310: 34305: 34300: 34295: 34290: 34285: 34280: 34275: 34270: 34265: 34259: 34257: 34246: 34245: 34243: 34242: 34237: 34232: 34227: 34222: 34217: 34212: 34207: 34202: 34197: 34192: 34186: 34184: 34173: 34172: 34170: 34169: 34164: 34159: 34154: 34149: 34144: 34139: 34134: 34129: 34124: 34118: 34116: 34105: 34104: 34102: 34101: 34096: 34091: 34086: 34081: 34076: 34071: 34066: 34061: 34056: 34051: 34046: 34040: 34038: 34027: 34026: 34024: 34023: 34018: 34013: 34008: 34003: 33998: 33993: 33988: 33983: 33978: 33973: 33968: 33962: 33960: 33949: 33948: 33946: 33945: 33940: 33934: 33932: 33918: 33902: 33901: 33896: 33891: 33886: 33881: 33876: 33871: 33866: 33861: 33856: 33851: 33846: 33841: 33836: 33831: 33826: 33821: 33816: 33811: 33806: 33801: 33796: 33791: 33786: 33781: 33776: 33771: 33766: 33761: 33756: 33751: 33746: 33741: 33736: 33731: 33726: 33721: 33716: 33711: 33706: 33701: 33696: 33691: 33686: 33681: 33676: 33671: 33666: 33661: 33656: 33651: 33646: 33641: 33636: 33631: 33626: 33621: 33616: 33611: 33606: 33601: 33596: 33591: 33586: 33581: 33575: 33573: 33561: 33553: 33552: 33550: 33549: 33544: 33539: 33534: 33529: 33524: 33519: 33514: 33509: 33504: 33499: 33494: 33489: 33484: 33479: 33474: 33469: 33464: 33459: 33454: 33449: 33444: 33439: 33434: 33429: 33424: 33419: 33414: 33409: 33404: 33399: 33394: 33389: 33383: 33381: 33373: 33372: 33370: 33369: 33364: 33359: 33354: 33349: 33344: 33339: 33334: 33328: 33326: 33317: 33310: 33299: 33298: 33291: 33290: 33283: 33276: 33268: 33259: 33258: 33255: 33254: 33251: 33250: 33248: 33247: 33242: 33237: 33236: 33235: 33230: 33222: 33217: 33211: 33209: 33203: 33202: 33200: 33199: 33194: 33189: 33184: 33179: 33174: 33169: 33164: 33159: 33154: 33149: 33143: 33141: 33140:Harm reduction 33137: 33136: 33134: 33133: 33132: 33131: 33123: 33118: 33113: 33108: 33103: 33098: 33097: 33096: 33086: 33081: 33076: 33074:Date rape drug 33071: 33066: 33060: 33058: 33052: 33051: 33048: 33047: 33045: 33044: 33043: 33042: 33040:Liquor license 33037: 33032: 33027: 33017: 33015:Darknet market 33012: 33011: 33010: 33005: 33000: 32995: 32990: 32985: 32980: 32975: 32970: 32965: 32960: 32955: 32950: 32945: 32940: 32935: 32930: 32925: 32920: 32915: 32910: 32905: 32900: 32895: 32890: 32885: 32880: 32875: 32870: 32865: 32860: 32855: 32850: 32845: 32840: 32835: 32830: 32825: 32820: 32815: 32810: 32805: 32800: 32795: 32790: 32785: 32780: 32775: 32770: 32765: 32760: 32755: 32750: 32745: 32740: 32735: 32730: 32725: 32720: 32715: 32710: 32705: 32700: 32695: 32684: 32682: 32678: 32677: 32675: 32674: 32669: 32664: 32659: 32653: 32651: 32642: 32630: 32629: 32619: 32618: 32615: 32614: 32611: 32610: 32608: 32607: 32605:Zero tolerance 32602: 32601: 32600: 32595: 32590: 32580: 32575: 32570: 32565: 32560: 32555: 32550: 32545: 32540: 32535: 32529: 32527: 32523: 32522: 32520: 32519: 32514: 32509: 32504: 32499: 32494: 32489: 32484: 32478: 32476: 32472: 32471: 32469: 32468: 32467: 32466: 32461: 32456: 32451: 32446: 32441: 32436: 32431: 32421: 32416: 32411: 32406: 32401: 32396: 32391: 32386: 32381: 32379:Czech Republic 32376: 32371: 32365: 32363: 32357: 32356: 32354: 32353: 32352: 32351: 32346: 32341: 32340: 32339: 32332:Liberalization 32329: 32324: 32322:Harm reduction 32319: 32314: 32304: 32303: 32302: 32297: 32292: 32287: 32282: 32271: 32269: 32265: 32264: 32262: 32261: 32260: 32259: 32254: 32249: 32241: 32240: 32239: 32234: 32229: 32218: 32216: 32208: 32207: 32197: 32196: 32193: 32192: 32189: 32188: 32186: 32185: 32180: 32175: 32170: 32165: 32160: 32155: 32150: 32148:Party and play 32145: 32140: 32138:Needle sharing 32135: 32130: 32125: 32120: 32115: 32110: 32105: 32100: 32094: 32092: 32088: 32087: 32085: 32084: 32079: 32074: 32069: 32064: 32059: 32054: 32052:Cigarette card 32048: 32046: 32040: 32039: 32037: 32036: 32031: 32026: 32021: 32016: 32011: 32006: 32001: 31996: 31991: 31985: 31983: 31977: 31976: 31974: 31973: 31968: 31963: 31961:Tailgate party 31958: 31953: 31948: 31943: 31938: 31933: 31928: 31923: 31918: 31913: 31911:Drinking games 31908: 31903: 31901:Binge drinking 31898: 31893: 31888: 31882: 31880: 31874: 31873: 31871: 31870: 31865: 31860: 31855: 31849: 31847: 31845:Coffee culture 31841: 31840: 31838: 31837: 31832: 31827: 31822: 31817: 31812: 31807: 31802: 31797: 31792: 31787: 31782: 31777: 31772: 31767: 31762: 31757: 31752: 31747: 31741: 31739: 31729: 31728: 31716: 31715: 31712: 31711: 31708: 31707: 31705: 31704: 31699: 31689: 31688: 31687: 31682: 31672: 31667: 31661: 31659: 31653: 31652: 31649: 31648: 31646: 31645: 31640: 31634: 31632: 31626: 31625: 31623: 31622: 31621: 31620: 31615: 31610: 31605: 31595: 31594: 31593: 31588: 31583: 31572: 31570: 31564: 31563: 31561: 31560: 31555: 31553:Dimenhydrinate 31550: 31549: 31548: 31543: 31538: 31533: 31518: 31516: 31510: 31509: 31507: 31506: 31505: 31504: 31494: 31489: 31488: 31487: 31477: 31472: 31467: 31466: 31465: 31460: 31455: 31453:alkyl nitrites 31450: 31435: 31430: 31419: 31417: 31411: 31410: 31408: 31407: 31406: 31405: 31391: 31390: 31389: 31384: 31379: 31377:Peruvian torch 31369: 31364: 31359: 31358: 31357: 31347: 31346: 31345: 31340: 31335: 31324: 31322: 31313: 31307: 31306: 31304: 31303: 31302: 31301: 31296: 31286: 31281: 31276: 31275: 31274: 31266: 31260: 31258: 31252: 31251: 31249: 31248: 31247: 31246: 31241: 31231: 31230: 31229: 31224: 31219: 31209: 31204: 31199: 31194: 31189: 31184: 31179: 31178: 31177: 31167: 31166: 31165: 31160: 31150: 31149: 31148: 31138: 31137: 31136: 31131: 31126: 31116: 31111: 31110: 31109: 31099: 31093: 31091: 31085: 31084: 31082: 31081: 31076: 31075: 31074: 31064: 31063: 31062: 31052: 31051: 31050: 31040: 31035: 31034: 31033: 31025: 31020: 31019: 31018: 31010: 31005: 31004: 31003: 31000: 30992: 30991: 30990: 30982: 30981: 30980: 30970: 30969: 30968: 30965: 30956: 30954: 30948: 30947: 30945: 30944: 30942:Quinazolinones 30939: 30934: 30929: 30928: 30927: 30926: 30925: 30917: 30916: 30915: 30910: 30905: 30900: 30889: 30888: 30887: 30869: 30864: 30862:Gabapentinoids 30859: 30858: 30857: 30852: 30847: 30837: 30832: 30827: 30821: 30819: 30809: 30808: 30798: 30797: 30790: 30789: 30782: 30775: 30767: 30761: 30758: 30757: 30743: 30742: 30737: 30736: 30733: 30732: 30731: 30730: 30727: 30716: 30710: 30704: 30703: 30700: 30699: 30696: 30695: 30693: 30692: 30687: 30682: 30673: 30665: 30648: 30642:Ademetionine ( 30638: 30635: 30634: 30624: 30623: 30620: 30619: 30617: 30616: 30612: 30604: 30594: 30580: 30575: 30544: 30541: 30540: 30528: 30527: 30524: 30523: 30520: 30519: 30517: 30516: 30507: 30505: 30496: 30490: 30489: 30487: 30486: 30481: 30476: 30471: 30466: 30461: 30456: 30447: 30445: 30436: 30430: 30429: 30427: 30426: 30417: 30416: 30407: 30406: 30401: 30396: 30391: 30386: 30381: 30376: 30371: 30366: 30361: 30356: 30351: 30346: 30341: 30336: 30331: 30322: 30320: 30312: 30311: 30299: 30298: 30295: 30294: 30291: 30290: 30288: 30287: 30281: 30279: 30275: 30274: 30272: 30271: 30266: 30261: 30256: 30250: 30248: 30237: 30236: 30234: 30233: 30228: 30223: 30218: 30213: 30208: 30203: 30198: 30193: 30188: 30183: 30178: 30173: 30168: 30163: 30161:Imipraminoxide 30158: 30153: 30148: 30143: 30138: 30133: 30128: 30123: 30118: 30113: 30108: 30103: 30098: 30092: 30090: 30075: 30074: 30058: 30057: 30054: 30053: 30050: 30049: 30047: 30046: 30041: 30036: 30031: 30026: 30021: 30016: 30011: 30006: 30001: 29996: 29991: 29986: 29981: 29976: 29971: 29965: 29963: 29959: 29958: 29956: 29955: 29950: 29944: 29942: 29931: 29930: 29928: 29927: 29922: 29917: 29911: 29909: 29898: 29897: 29895: 29894: 29889: 29884: 29878: 29876: 29865: 29864: 29862: 29861: 29856: 29851: 29845: 29843: 29832: 29831: 29829: 29828: 29823: 29818: 29812: 29810: 29799: 29798: 29796: 29795: 29790: 29785: 29780: 29775: 29770: 29768:Desvenlafaxine 29764: 29762: 29751: 29750: 29748: 29747: 29742: 29737: 29732: 29727: 29722: 29717: 29712: 29706: 29704: 29689: 29688: 29671: 29670: 29658: 29657: 29650: 29643: 29635: 29626: 29625: 29622: 29621: 29620: 29619: 29616: 29605: 29599: 29593: 29592: 29589: 29588: 29586: 29585: 29580: 29575: 29570: 29565: 29563:Methoxyflurane 29560: 29555: 29550: 29545: 29540: 29535: 29530: 29525: 29520: 29514: 29512: 29508: 29507: 29505: 29504: 29499: 29494: 29489: 29484: 29479: 29473: 29471: 29465: 29464: 29461: 29460: 29458: 29457: 29451: 29449: 29443: 29442: 29440: 29439: 29434: 29429: 29421: 29416: 29415: 29405: 29400: 29395: 29381: 29376: 29370: 29368: 29362: 29361: 29359: 29358: 29353: 29348: 29343: 29338: 29333: 29328: 29322: 29320: 29311: 29303: 29302: 29300: 29299: 29294: 29289: 29284: 29279: 29273: 29271: 29265: 29264: 29261: 29260: 29258: 29257: 29252: 29247: 29242: 29237: 29232: 29226: 29224: 29220: 29219: 29217: 29216: 29206:Propyphenazone 29203: 29198: 29193: 29188: 29183: 29181:Aminophenazone 29177: 29175: 29169: 29168: 29166: 29165: 29152: 29147: 29142: 29137: 29132: 29127: 29122: 29117: 29112: 29107: 29102: 29097: 29092: 29087: 29082: 29077: 29072: 29061: 29059: 29053: 29052: 29050: 29049: 29044: 29042:Mefenamic acid 29039: 29034: 29028: 29026: 29020: 29019: 29017: 29016: 29011: 29006: 29001: 28996: 28991: 28977: 28975: 28969: 28968: 28966: 28965: 28960: 28955: 28950: 28945: 28932: 28927: 28922: 28917: 28911: 28909: 28905: 28904: 28902: 28901: 28896: 28891: 28886: 28881: 28875: 28873: 28869: 28868: 28866: 28865: 28860: 28855: 28850: 28845: 28840: 28835: 28822: 28801: 28796: 28791: 28785: 28783: 28776: 28770: 28769: 28767: 28766: 28761: 28756: 28751: 28750: 28749: 28744: 28739: 28734: 28729: 28724: 28719: 28714: 28704: 28699: 28694: 28688: 28686: 28679: 28678: 28675: 28674: 28672: 28671: 28666: 28649: 28644: 28639: 28634: 28629: 28624: 28619: 28614: 28609: 28604: 28599: 28594: 28589: 28584: 28579: 28574: 28569: 28564: 28559: 28554: 28549: 28539: 28534: 28529: 28524: 28519: 28514: 28512:Dextromoramide 28509: 28504: 28499: 28494: 28489: 28483: 28481: 28477: 28476: 28474: 28473: 28468: 28463: 28458: 28429: 28424: 28419: 28414: 28409: 28404: 28399: 28394: 28392:Hydromorphinol 28389: 28368: 28363: 28358: 28353: 28343:Dihydrocodeine 28340: 28335: 28330: 28325: 28312: 28310:Benzylmorphine 28307: 28301: 28299: 28295: 28294: 28292: 28291: 28286: 28281: 28276: 28266: 28265: 28264: 28259: 28248: 28246: 28233: 28227: 28226: 28210: 28209: 28202: 28195: 28187: 28178: 28177: 28174: 28173: 28172: 28171: 28168: 28157: 28151: 28145: 28144: 28141: 28140: 28137: 28136: 28134: 28133: 28128: 28122: 28120: 28116: 28115: 28113: 28112: 28107: 28102: 28096: 28094: 28088: 28087: 28085: 28084: 28079: 28074: 28069: 28063: 28061: 28055: 28054: 28052: 28051: 28046: 28040: 28035: 28030: 28025: 28020: 28015: 28010: 28004: 28002: 27996: 27995: 27993: 27992: 27987: 27982: 27977: 27971: 27969: 27963: 27962: 27960: 27959: 27954: 27949: 27944: 27939: 27934: 27929: 27923: 27921: 27915: 27914: 27912: 27911: 27906: 27901: 27895: 27893: 27884: 27878: 27877: 27875: 27874: 27869: 27864: 27859: 27854: 27849: 27847:Methoxypropane 27844: 27842:Methoxyflurane 27839: 27834: 27829: 27824: 27819: 27814: 27809: 27804: 27799: 27793: 27791: 27785: 27784: 27772: 27771: 27764: 27757: 27749: 27743: 27740: 27739: 27725: 27724: 27719: 27718: 27708: 27705: 27704: 27702: 27701: 27696: 27691: 27686: 27681: 27676: 27671: 27666: 27661: 27656: 27651: 27646: 27641: 27636: 27631: 27626: 27616: 27611: 27606: 27601: 27596: 27591: 27589:Chlorpromazine 27586: 27581: 27576: 27571: 27566: 27561: 27552: 27551: 27542: 27541: 27536: 27531: 27526: 27521: 27516: 27511: 27506: 27501: 27496: 27491: 27486: 27477: 27476: 27471: 27466: 27461: 27456: 27451: 27446: 27437: 27435: 27431: 27430: 27428: 27427: 27422: 27417: 27412: 27402: 27397: 27392: 27387: 27382: 27377: 27372: 27367: 27357: 27347: 27342: 27337: 27332: 27327: 27322: 27313: 27312: 27307: 27302: 27297: 27292: 27287: 27282: 27277: 27272: 27263: 27262: 27257: 27252: 27247: 27242: 27237: 27232: 27227: 27219: 27214: 27209: 27204: 27199: 27194: 27189: 27184: 27179: 27174: 27165: 27163: 27159: 27154: 27153: 27151: 27150: 27145: 27140: 27135: 27130: 27125: 27120: 27115: 27110: 27105: 27100: 27095: 27090: 27085: 27080: 27075: 27065: 27055: 27047: 27042: 27037: 27032: 27030:Chlorpromazine 27027: 27022: 27017: 27012: 27007: 27002: 26997: 26992: 26987: 26982: 26973: 26972: 26967: 26951: 26950: 26945: 26940: 26935: 26930: 26925: 26920: 26915: 26910: 26905: 26900: 26895: 26890: 26885: 26883:E-52862 (S1RA) 26880: 26875: 26870: 26865: 26860: 26855: 26850: 26845: 26840: 26835: 26830: 26825: 26816: 26815: 26810: 26805: 26800: 26795: 26790: 26785: 26780: 26775: 26770: 26765: 26760: 26755: 26750: 26748:Neuropeptide Y 26745: 26740: 26735: 26730: 26725: 26720: 26712: 26707: 26702: 26697: 26692: 26687: 26682: 26677: 26672: 26667: 26662: 26657: 26652: 26647: 26642: 26637: 26632: 26630:Dextrallorphan 26627: 26617: 26607: 26602: 26597: 26592: 26587: 26577: 26572: 26567: 26562: 26557: 26552: 26547: 26542: 26537: 26532: 26527: 26518: 26516: 26512: 26507: 26506: 26500:Sigma receptor 26496: 26495: 26488: 26481: 26473: 26464: 26463: 26461: 26460: 26450: 26449: 26444: 26439: 26434: 26429: 26420: 26419: 26414: 26409: 26404: 26399: 26394: 26389: 26384: 26379: 26374: 26369: 26364: 26359: 26354: 26349: 26347:-Phenylalanine 26341: 26336: 26331: 26319: 26317: 26313: 26312: 26309: 26308: 26306: 26305: 26300: 26295: 26290: 26285: 26280: 26275: 26270: 26265: 26260: 26255: 26250: 26245: 26240: 26236: 26231: 26229: 26225: 26224: 26222: 26221: 26216: 26211: 26206: 26201: 26196: 26191: 26186: 26181: 26176: 26174:Racemethorphan 26171: 26166: 26162: 26158: 26153: 26148: 26143: 26138: 26133: 26128: 26123: 26121:Levomethorphan 26118: 26113: 26108: 26103: 26098: 26093: 26088: 26084: 26080: 26076: 26072: 26068: 26064: 26060: 26056: 26052: 26046: 26044: 26037: 26029: 26028: 26025: 26024: 26022: 26021: 26016: 26011: 26006: 26001: 25996: 25991: 25986: 25981: 25976: 25971: 25966: 25961: 25956: 25951: 25946: 25941: 25936: 25931: 25926: 25921: 25916: 25911: 25906: 25901: 25896: 25891: 25886: 25881: 25876: 25871: 25866: 25861: 25856: 25851: 25846: 25841: 25836: 25831: 25826: 25821: 25816: 25811: 25806: 25801: 25796: 25791: 25786: 25781: 25776: 25771: 25766: 25761: 25756: 25751: 25746: 25741: 25735: 25733: 25729: 25728: 25726: 25725: 25720: 25715: 25710: 25705: 25683: 25678: 25673: 25668: 25663: 25658: 25653: 25648: 25638: 25633: 25628: 25626:Racemethorphan 25623: 25618: 25613: 25608: 25603: 25598: 25593: 25588: 25583: 25578: 25573: 25568: 25563: 25558: 25553: 25548: 25543: 25538: 25533: 25528: 25523: 25518: 25513: 25508: 25503: 25498: 25493: 25488: 25483: 25478: 25473: 25468: 25463: 25458: 25453: 25448: 25446:Levomethorphan 25443: 25438: 25433: 25428: 25423: 25418: 25413: 25408: 25403: 25398: 25393: 25388: 25383: 25378: 25373: 25368: 25363: 25358: 25353: 25348: 25343: 25338: 25333: 25328: 25323: 25318: 25313: 25308: 25303: 25298: 25293: 25288: 25283: 25278: 25273: 25268: 25263: 25258: 25253: 25248: 25243: 25238: 25233: 25228: 25223: 25218: 25213: 25208: 25203: 25198: 25193: 25188: 25183: 25178: 25173: 25168: 25163: 25158: 25153: 25148: 25143: 25138: 25132: 25130: 25123: 25115: 25114: 25111: 25110: 25108: 25107: 25102: 25097: 25092: 25087: 25082: 25077: 25072: 25067: 25062: 25057: 25052: 25047: 25042: 25037: 25032: 25027: 25022: 25017: 25012: 25007: 25002: 24997: 24992: 24987: 24982: 24977: 24972: 24967: 24962: 24957: 24952: 24947: 24942: 24937: 24932: 24927: 24922: 24917: 24912: 24907: 24901: 24899: 24895: 24894: 24892: 24891: 24886: 24881: 24876: 24871: 24866: 24861: 24856: 24851: 24846: 24841: 24836: 24831: 24826: 24821: 24816: 24814:Racemethorphan 24811: 24806: 24801: 24796: 24791: 24786: 24781: 24776: 24771: 24766: 24761: 24756: 24751: 24746: 24741: 24736: 24731: 24726: 24724:Levomethorphan 24721: 24719:Leu-enkephalin 24716: 24711: 24706: 24701: 24696: 24691: 24686: 24681: 24676: 24671: 24666: 24661: 24656: 24651: 24646: 24641: 24636: 24631: 24626: 24621: 24616: 24611: 24606: 24601: 24596: 24591: 24586: 24581: 24576: 24571: 24566: 24561: 24556: 24551: 24546: 24541: 24536: 24531: 24526: 24521: 24516: 24511: 24506: 24501: 24496: 24491: 24486: 24481: 24475: 24473: 24466: 24458: 24457: 24454: 24453: 24451: 24450: 24445: 24440: 24435: 24430: 24425: 24420: 24415: 24410: 24405: 24400: 24398:Naltrexonazine 24395: 24390: 24385: 24380: 24375: 24370: 24365: 24360: 24355: 24350: 24345: 24340: 24335: 24330: 24325: 24320: 24315: 24310: 24305: 24300: 24295: 24290: 24285: 24280: 24275: 24270: 24265: 24260: 24255: 24250: 24245: 24240: 24235: 24232: 24227: 24222: 24217: 24212: 24207: 24202: 24197: 24192: 24187: 24182: 24177: 24172: 24167: 24162: 24157: 24152: 24147: 24142: 24137: 24132: 24127: 24121: 24119: 24115: 24114: 24112: 24111: 24106: 24101: 24096: 24091: 24086: 24081: 24076: 24071: 24066: 24061: 24056: 24051: 24046: 24041: 24036: 24031: 24026: 24021: 24016: 24011: 24006: 24001: 23999:Racemethorphan 23996: 23991: 23986: 23981: 23976: 23971: 23966: 23961: 23956: 23951: 23946: 23941: 23929: 23924: 23919: 23914: 23909: 23904: 23899: 23894: 23889: 23884: 23879: 23874: 23869: 23864: 23859: 23854: 23849: 23844: 23839: 23834: 23829: 23824: 23819: 23814: 23809: 23804: 23799: 23794: 23789: 23784: 23779: 23774: 23769: 23764: 23759: 23754: 23749: 23744: 23742:Levomethorphan 23739: 23734: 23732:Leu-enkephalin 23729: 23724: 23719: 23714: 23709: 23704: 23699: 23694: 23692:Hydromorphinol 23689: 23684: 23679: 23674: 23669: 23664: 23659: 23654: 23649: 23644: 23639: 23634: 23629: 23624: 23619: 23614: 23609: 23604: 23599: 23594: 23589: 23587:Dihydrocodeine 23584: 23579: 23574: 23569: 23564: 23559: 23554: 23552:Dextromoramide 23549: 23544: 23539: 23534: 23529: 23524: 23519: 23514: 23509: 23504: 23499: 23494: 23489: 23484: 23479: 23474: 23469: 23464: 23459: 23457:Benzylmorphine 23454: 23449: 23444: 23439: 23434: 23429: 23424: 23419: 23414: 23409: 23404: 23399: 23394: 23389: 23387:Acetylfentanyl 23384: 23379: 23374: 23369: 23364: 23359: 23354: 23348: 23346: 23332: 23324: 23323: 23313: 23312: 23305: 23298: 23290: 23281: 23280: 23244: 23241: 23240: 23238: 23237: 23225: 23213: 23212: 23207:DAT enhancers: 23203: 23201: 23197: 23196: 23194: 23193: 23188: 23183: 23178: 23173: 23168: 23163: 23158: 23153: 23148: 23143: 23138: 23133: 23128: 23123: 23118: 23113: 23108: 23103: 23085: 23079: 23077: 23066: 23065: 23062: 23061: 23059: 23058: 23053: 23023: 23018: 23013: 23008: 23003: 22998: 22993: 22988: 22983: 22978: 22973: 22968: 22942: 22931:Antipsychotics 22928: 22925:tripelennamine 22909:dimenhydrinate 22905:chlorphenamine 22897:Antihistamines 22894: 22889: 22880: 22877: 22876: 22874: 22873: 22868: 22863: 22858: 22853: 22848: 22843: 22838: 22833: 22831:Cyanodothiepin 22828: 22823: 22818: 22809: 22806: 22805: 22803: 22802: 22792: 22787: 22782: 22777: 22772: 22767: 22762: 22757: 22752: 22747: 22742: 22737: 22732: 22727: 22722: 22717: 22712: 22707: 22702: 22697: 22692: 22687: 22682: 22677: 22672: 22667: 22662: 22657: 22652: 22647: 22642: 22637: 22632: 22627: 22622: 22617: 22608: 22605: 22604: 22602: 22601: 22596: 22591: 22586: 22581: 22576: 22571: 22566: 22561: 22556: 22554:Desvenlafaxine 22551: 22546: 22541: 22532: 22529: 22528: 22526: 22525: 22520: 22515: 22510: 22505: 22500: 22495: 22490: 22485: 22480: 22471: 22470: 22465: 22460: 22455: 22450: 22445: 22440: 22435: 22430: 22425: 22420: 22415: 22410: 22405: 22400: 22395: 22390: 22385: 22380: 22375: 22370: 22365: 22360: 22355: 22346: 22340: 22316: 22315: 22312: 22311: 22309: 22308: 22278: 22273: 22268: 22261: 22256: 22251: 22237: 22226:Antipsychotics 22223: 22220:tripelennamine 22212:chlorphenamine 22204:Antihistamines 22197: 22194: 22193: 22191: 22190: 22185: 22180: 22175: 22170: 22161: 22158: 22157: 22155: 22154: 22149: 22144: 22139: 22134: 22129: 22124: 22119: 22114: 22109: 22104: 22099: 22094: 22085: 22082: 22081: 22079: 22078: 22068: 22063: 22058: 22053: 22048: 22043: 22038: 22033: 22028: 22023: 22018: 22013: 22008: 22003: 21998: 21993: 21988: 21983: 21978: 21973: 21968: 21963: 21958: 21953: 21948: 21943: 21938: 21933: 21928: 21923: 21918: 21913: 21908: 21903: 21898: 21893: 21884: 21881: 21880: 21878: 21877: 21872: 21867: 21862: 21857: 21852: 21847: 21842: 21837: 21832: 21827: 21825:Desvenlafaxine 21822: 21817: 21808: 21805: 21804: 21802: 21801: 21796: 21791: 21786: 21781: 21776: 21771: 21766: 21761: 21756: 21751: 21746: 21741: 21736: 21731: 21722: 21719: 21718: 21716: 21715: 21710: 21705: 21700: 21695: 21690: 21685: 21680: 21675: 21670: 21665: 21660: 21655: 21650: 21645: 21636: 21630: 21606: 21605: 21602: 21601: 21599: 21598: 21593: 21591:Tripelennamine 21588: 21583: 21578: 21573: 21568: 21563: 21558: 21553: 21548: 21543: 21538: 21533: 21528: 21523: 21518: 21513: 21508: 21503: 21498: 21493: 21488: 21483: 21478: 21473: 21468: 21463: 21458: 21453: 21448: 21443: 21438: 21433: 21428: 21423: 21418: 21413: 21408: 21403: 21398: 21393: 21388: 21383: 21378: 21373: 21368: 21363: 21358: 21353: 21348: 21341: 21336: 21331: 21326: 21321: 21316: 21314:Amfonelic acid 21311: 21306: 21301: 21292: 21289: 21288: 21286: 21285: 21280: 21275: 21270: 21265: 21260: 21255: 21250: 21245: 21240: 21235: 21230: 21225: 21220: 21215: 21210: 21205: 21200: 21195: 21190: 21185: 21180: 21175: 21170: 21165: 21160: 21155: 21146: 21143: 21142: 21140: 21139: 21134: 21129: 21124: 21119: 21110: 21107: 21106: 21104: 21103: 21098: 21093: 21088: 21083: 21078: 21073: 21068: 21066:Ethylphenidate 21063: 21058: 21053: 21048: 21043: 21034: 21031: 21030: 21028: 21027: 21022: 21017: 21012: 21007: 21002: 20997: 20992: 20983: 20977: 20953: 20952: 20945: 20944: 20937: 20930: 20922: 20913: 20912: 20910: 20909: 20902: 20895: 20884: 20881: 20880: 20878: 20877: 20865: 20864: 20854: 20849: 20844: 20839: 20834: 20829: 20824: 20819: 20814: 20809: 20804: 20799: 20794: 20789: 20784: 20779: 20774: 20769: 20761: 20756: 20751: 20746: 20734: 20729: 20724: 20719: 20714: 20709: 20704: 20699: 20694: 20689: 20687:Methoxyflurane 20684: 20679: 20674: 20669: 20664: 20659: 20654: 20649: 20644: 20639: 20634: 20622: 20617: 20605: 20600: 20595: 20583: 20578: 20573: 20568: 20563: 20558: 20553: 20548: 20543: 20538: 20533: 20528: 20519: 20514: 20509: 20504: 20499: 20494: 20489: 20484: 20479: 20474: 20469: 20464: 20459: 20454: 20449: 20444: 20439: 20434: 20432:Nitromemantine 20429: 20424: 20419: 20414: 20409: 20404: 20399: 20394: 20389: 20384: 20379: 20374: 20369: 20367:Levomethorphan 20364: 20359: 20354: 20349: 20344: 20339: 20334: 20329: 20324: 20319: 20314: 20309: 20304: 20299: 20294: 20289: 20287:Dieticyclidine 20284: 20279: 20274: 20269: 20267:Dextrallorphan 20264: 20259: 20254: 20249: 20244: 20239: 20234: 20229: 20224: 20222:Argiotoxin-636 20219: 20214: 20209: 20204: 20199: 20194: 20189: 20184: 20179: 20174: 20169: 20164: 20159: 20147: 20142: 20137: 20135:Diaminopropane 20132: 20127: 20115: 20110: 20105: 20100: 20095: 20090: 20085: 20080: 20075: 20070: 20065: 20063:Kynurenic acid 20060: 20055: 20050: 20045: 20040: 20035: 20027: 20022: 20017: 20012: 20007: 20002: 19997: 19992: 19987: 19982: 19977: 19965: 19960: 19955: 19950: 19945: 19940: 19935: 19930: 19925: 19920: 19915: 19910: 19905: 19900: 19895: 19890: 19885: 19880: 19875: 19870: 19865: 19853: 19852: 19847: 19842: 19837: 19832: 19827: 19822: 19809: 19794: 19778: 19773: 19761: 19756: 19751: 19746: 19738: 19730: 19725: 19720: 19715: 19710: 19705: 19697: 19689: 19681: 19676: 19671: 19666: 19661: 19656: 19651: 19646: 19630: 19625: 19620: 19615: 19610: 19605: 19600: 19591: 19586: 19581: 19569: 19567: 19556: 19555: 19553: 19552: 19547: 19542: 19537: 19532: 19527: 19506: 19501: 19496: 19491: 19486: 19481: 19476: 19471: 19466: 19464:Kynurenic acid 19461: 19456: 19451: 19446: 19441: 19436: 19427: 19426: 19421: 19416: 19411: 19406: 19394: 19389: 19384: 19379: 19374: 19369: 19364: 19359: 19354: 19349: 19344: 19339: 19327: 19325: 19314: 19313: 19311: 19310: 19298: 19293: 19288: 19283: 19278: 19273: 19268: 19263: 19258: 19253: 19248: 19243: 19238: 19217: 19212: 19207: 19202: 19197: 19192: 19187: 19182: 19177: 19172: 19170:Kynurenic acid 19167: 19162: 19157: 19152: 19147: 19142: 19137: 19132: 19127: 19122: 19113: 19112: 19107: 19102: 19097: 19092: 19087: 19082: 19077: 19072: 19067: 19062: 19057: 19052: 19047: 19042: 19037: 19032: 19027: 19022: 19017: 19012: 19007: 19002: 18997: 18992: 18987: 18982: 18970: 18965: 18960: 18955: 18950: 18945: 18940: 18935: 18930: 18918: 18916: 18905: 18904: 18894: 18893: 18886: 18879: 18871: 18862: 18861: 18847: 18844: 18843: 18840: 18839: 18837: 18836: 18828: 18826: 18815: 18814: 18812: 18811: 18803: 18801: 18787: 18783: 18782: 18779: 18778: 18775: 18774: 18772: 18771: 18766: 18761: 18756: 18751: 18746: 18744:Mefenamic acid 18741: 18736: 18731: 18725: 18723: 18714: 18710: 18709: 18706: 18705: 18703: 18702: 18700:Phenanthridine 18697: 18692: 18687: 18682: 18677: 18671: 18669: 18663: 18662: 18660: 18659: 18654: 18649: 18643: 18641: 18632: 18621: 18620: 18617: 18616: 18614: 18613: 18607: 18605: 18599: 18598: 18596: 18595: 18590: 18585: 18580: 18575: 18570: 18565: 18560: 18555: 18550: 18544: 18542: 18533: 18519: 18513: 18512: 18509: 18508: 18505: 18504: 18502: 18501: 18496: 18491: 18486: 18481: 18475: 18473: 18464: 18453: 18452: 18449: 18448: 18446: 18445: 18439: 18437: 18431: 18430: 18428: 18427: 18422: 18417: 18411: 18409: 18400: 18389: 18388: 18385: 18384: 18382: 18381: 18376: 18371: 18366: 18361: 18348:Atracotoxins ( 18346: 18340: 18338: 18332: 18331: 18329: 18328: 18323: 18318: 18308: 18303: 18294: 18293: 18291:Zetekitoxin AB 18288: 18283: 18278: 18273: 18264: 18263: 18258: 18253: 18248: 18243: 18238: 18233: 18228: 18223: 18218: 18209: 18208: 18203: 18198: 18193: 18191:Proxymetacaine 18188: 18183: 18178: 18173: 18168: 18163: 18158: 18153: 18148: 18143: 18138: 18133: 18128: 18123: 18118: 18113: 18108: 18103: 18101:Chloroprocaine 18098: 18093: 18088: 18074: 18069: 18064: 18059: 18047: 18046: 18041: 18036: 18031: 18026: 18021: 18016: 18011: 18006: 18001: 17996: 17991: 17986: 17981: 17976: 17971: 17966: 17961: 17956: 17951: 17946: 17941: 17936: 17931: 17926: 17921: 17916: 17907: 17906: 17901: 17896: 17891: 17886: 17881: 17876: 17871: 17866: 17861: 17856: 17851: 17846: 17841: 17836: 17831: 17826: 17821: 17812: 17811: 17802: 17800: 17791: 17777: 17771: 17770: 17767: 17766: 17763: 17762: 17760: 17759: 17753: 17751: 17745: 17744: 17742: 17741: 17736: 17731: 17726: 17720: 17718: 17709: 17698: 17697: 17694: 17693: 17691: 17690: 17685: 17680: 17675: 17670: 17665: 17656: 17650: 17648: 17642: 17641: 17639: 17638: 17633: 17624: 17618: 17616: 17607: 17599: 17593: 17592: 17589: 17588: 17586: 17585: 17568: 17567: 17562: 17557: 17552: 17547: 17542: 17537: 17532: 17527: 17522: 17517: 17512: 17507: 17502: 17489: 17482: 17480: 17474: 17473: 17471: 17470: 17465: 17460: 17455: 17450: 17445: 17440: 17435: 17430: 17413: 17412: 17407: 17402: 17397: 17392: 17387: 17382: 17377: 17375:Glyclopyramide 17372: 17367: 17362: 17357: 17352: 17347: 17342: 17337: 17332: 17330:Chlorpropamide 17327: 17322: 17309: 17302: 17300: 17291: 17280: 17279: 17276: 17275: 17273: 17272: 17267: 17257: 17251: 17249: 17243: 17242: 17240: 17239: 17234: 17229: 17219: 17213: 17212: 17207: 17202: 17197: 17192: 17187: 17182: 17177: 17172: 17167: 17162: 17157: 17152: 17147: 17142: 17137: 17132: 17127: 17122: 17117: 17112: 17107: 17102: 17097: 17092: 17087: 17082: 17077: 17075:Clarithromycin 17072: 17067: 17065:Chlorpromazine 17062: 17057: 17052: 17047: 17042: 17037: 17032: 17027: 17022: 17017: 17012: 17004: 16996: 16995: 16990: 16985: 16980: 16975: 16970: 16965: 16960: 16955: 16950: 16945: 16940: 16935: 16930: 16925: 16920: 16915: 16910: 16905: 16900: 16895: 16890: 16885: 16880: 16875: 16870: 16865: 16860: 16855: 16850: 16845: 16840: 16835: 16830: 16825: 16820: 16814: 16812: 16803: 16789: 16783: 16782: 16779: 16778: 16775: 16774: 16772: 16771: 16759: 16757: 16751: 16750: 16748: 16747: 16742: 16737: 16732: 16727: 16722: 16717: 16712: 16707: 16702: 16697: 16692: 16687: 16685:Paramethadione 16682: 16677: 16672: 16667: 16662: 16657: 16652: 16647: 16642: 16637: 16632: 16627: 16622: 16617: 16612: 16607: 16602: 16597: 16592: 16587: 16582: 16577: 16572: 16567: 16562: 16557: 16552: 16547: 16542: 16533: 16532: 16527: 16522: 16517: 16512: 16507: 16502: 16497: 16492: 16487: 16482: 16477: 16472: 16467: 16460:gabapentinoids 16453: 16447: 16446: 16441: 16436: 16431: 16426: 16421: 16416: 16411: 16406: 16401: 16396: 16391: 16386: 16381: 16376: 16371: 16366: 16361:Non-selective: 16357: 16356: 16351: 16346: 16341: 16336: 16331: 16326: 16314: 16313: 16301: 16300: 16298:ω-Agatoxin IVB 16295: 16293:ω-Agatoxin IVA 16283: 16282: 16277: 16272: 16267: 16262: 16257: 16252: 16250:Huwentoxin XVI 16247: 16242: 16237: 16225: 16224: 16219: 16214: 16209: 16204: 16202:Cyproheptadine 16199: 16194: 16189: 16184: 16172: 16167: 16162: 16157: 16152: 16147: 16142: 16137: 16132: 16127: 16122: 16117: 16112: 16097: 16092: 16087: 16082: 16067: 16062: 16057: 16052: 16047: 16042: 16037: 16032: 16027: 16022: 16017: 16012: 16007: 16002: 15997: 15992: 15987: 15982: 15977: 15972: 15967: 15962: 15960:Levniguldipine 15957: 15952: 15947: 15942: 15937: 15932: 15927: 15922: 15917: 15912: 15907: 15902: 15900:Dexniguldipine 15897: 15892: 15887: 15882: 15877: 15872: 15867: 15849: 15847: 15838: 15824: 15818: 15817: 15810: 15809: 15802: 15795: 15787: 15778: 15777: 15775: 15774: 15765: 15756: 15747: 15738: 15729: 15720: 15707: 15704: 15703: 15700: 15699: 15697: 15696: 15691: 15686: 15681: 15676: 15671: 15666: 15661: 15656: 15651: 15646: 15641: 15636: 15631: 15626: 15621: 15616: 15611: 15606: 15601: 15596: 15591: 15586: 15581: 15576: 15574:Isocorypalmine 15571: 15566: 15561: 15556: 15551: 15546: 15541: 15536: 15531: 15526: 15521: 15516: 15511: 15501: 15500: 15495: 15490: 15485: 15480: 15470: 15469: 15464: 15459: 15454: 15449: 15444: 15442:Metoclopramide 15439: 15434: 15429: 15424: 15419: 15417:Deudomperidone 15414: 15409: 15404: 15399: 15394: 15389: 15384: 15382:Aceprometazine 15374: 15373: 15368: 15363: 15358: 15353: 15348: 15343: 15338: 15333: 15328: 15323: 15318: 15313: 15308: 15306:Piperacetazine 15303: 15298: 15293: 15283: 15278: 15273: 15268: 15263: 15258: 15253: 15248: 15243: 15238: 15233: 15228: 15223: 15218: 15213: 15208: 15203: 15198: 15193: 15188: 15183: 15178: 15173: 15168: 15158: 15157: 15155:Zuclopenthixol 15152: 15147: 15142: 15137: 15127: 15122: 15117: 15112: 15107: 15102: 15097: 15092: 15087: 15082: 15077: 15072: 15067: 15062: 15057: 15052: 15047: 15042: 15039:+amitriptyline 15032: 15027: 15022: 15017: 15012: 15007: 15002: 14997: 14992: 14987: 14982: 14977: 14972: 14967: 14962: 14957: 14952: 14947: 14937: 14932: 14927: 14922: 14917: 14912: 14907: 14902: 14897: 14892: 14887: 14885:Chlorpromazine 14882: 14877: 14872: 14867: 14862: 14857: 14852: 14847: 14845:Acetophenazine 14842: 14832: 14830: 14826: 14825: 14823: 14822: 14817: 14812: 14807: 14802: 14797: 14792: 14787: 14782: 14777: 14772: 14767: 14762: 14757: 14752: 14747: 14742: 14737: 14732: 14727: 14722: 14717: 14712: 14707: 14702: 14697: 14692: 14687: 14682: 14677: 14672: 14667: 14662: 14657: 14652: 14647: 14642: 14637: 14632: 14627: 14622: 14617: 14612: 14602: 14601: 14596: 14591: 14586: 14581: 14576: 14571: 14566: 14561: 14551: 14541: 14540: 14535: 14530: 14522: 14520:-Phenylalanine 14514: 14506: 14501: 14496: 14491: 14481: 14480: 14475: 14470: 14465: 14460: 14450: 14449: 14444: 14439: 14434: 14429: 14424: 14419: 14414: 14409: 14404: 14399: 14389: 14388: 14383: 14378: 14373: 14368: 14362:Aminotetralins 14358: 14357: 14352: 14347: 14337: 14335: 14328: 14323: 14318: 14317: 14314: 14313: 14311: 14310: 14305: 14300: 14295: 14290: 14285: 14280: 14270: 14269: 14264: 14259: 14254: 14249: 14244: 14239: 14234: 14224: 14219: 14214: 14209: 14204: 14199: 14194: 14189: 14184: 14174: 14173: 14171:Zuclopenthixol 14168: 14158: 14153: 14148: 14143: 14140:+amitriptyline 14133: 14128: 14123: 14113: 14108: 14106:Chlorpromazine 14103: 14093: 14091: 14087: 14086: 14084: 14083: 14078: 14073: 14063: 14061: 14057: 14056: 14054: 14053: 14048: 14043: 14038: 14033: 14028: 14023: 14018: 14013: 14008: 14003: 14001:Isocorypalmine 13998: 13993: 13983: 13982: 13977: 13969: 13967:-Phenylalanine 13961: 13956: 13948: 13943: 13938: 13933: 13928: 13918: 13917: 13912: 13907: 13902: 13897: 13892: 13887: 13877: 13876: 13871: 13866: 13861: 13856: 13851: 13846: 13836: 13835: 13830: 13825: 13820: 13815: 13810: 13805: 13800: 13795: 13785: 13783: 13776: 13771: 13766: 13765: 13755: 13754: 13747: 13740: 13732: 13723: 13722: 13717: 13716: 13714: 13713: 13708: 13703: 13698: 13694: 13691: 13690: 13688: 13687: 13682: 13677: 13672: 13667: 13662: 13657: 13652: 13647: 13642: 13632: 13627: 13621: 13619: 13605: 13604: 13601: 13600: 13598: 13597: 13592: 13587: 13582: 13577: 13572: 13567: 13562: 13557: 13552: 13547: 13542: 13537: 13532: 13527: 13522: 13517: 13512: 13507: 13502: 13497: 13492: 13487: 13482: 13477: 13472: 13467: 13462: 13457: 13452: 13447: 13442: 13437: 13432: 13427: 13422: 13417: 13412: 13407: 13402: 13397: 13392: 13387: 13385:Kynurenic acid 13382: 13377: 13372: 13367: 13362: 13357: 13352: 13347: 13342: 13337: 13332: 13327: 13322: 13317: 13312: 13307: 13302: 13297: 13292: 13287: 13282: 13277: 13272: 13267: 13262: 13257: 13252: 13247: 13242: 13237: 13232: 13227: 13222: 13217: 13212: 13207: 13202: 13197: 13192: 13187: 13182: 13179:κ-bungarotoxin 13175:α-bungarotoxin 13168: 13163: 13149: 13144: 13139: 13134: 13129: 13124: 13119: 13114: 13113:, many others) 13103:α-bungarotoxin 13096: 13091: 13085: 13083: 13066: 13065: 13063: 13062: 13057: 13052: 13047: 13042: 13037: 13035:Tribendimidine 13032: 13027: 13022: 13017: 13012: 13007: 13002: 12997: 12992: 12987: 12982: 12977: 12972: 12967: 12962: 12960:Sebacylcholine 12957: 12952: 12947: 12942: 12937: 12932: 12927: 12922: 12917: 12912: 12907: 12902: 12892: 12887: 12882: 12877: 12872: 12867: 12862: 12857: 12852: 12847: 12842: 12837: 12832: 12827: 12822: 12817: 12812: 12807: 12802: 12797: 12792: 12787: 12782: 12777: 12775:Butyrylcholine 12772: 12767: 12762: 12757: 12752: 12747: 12742: 12737: 12732: 12727: 12722: 12717: 12712: 12707: 12702: 12697: 12692: 12687: 12681: 12679: 12659: 12648: 12647: 12637: 12636: 12629: 12622: 12614: 12605: 12604: 12602: 12601: 12596: 12591: 12586: 12582: 12579: 12578: 12576: 12575: 12570: 12565: 12560: 12555: 12550: 12545: 12540: 12535: 12530: 12520: 12515: 12509: 12507: 12493: 12492: 12489: 12488: 12486: 12485: 12480: 12475: 12470: 12460: 12437:chlorpromazine 12430: 12425: 12420: 12415: 12410: 12405: 12400: 12395: 12390: 12308: 12303: 12298: 12293: 12288: 12283: 12278: 12256: 12251: 12246: 12227: 12222: 12217: 12212: 12207: 12202: 12197: 12192: 12187: 12182: 12177: 12172: 12167: 12162: 12157: 12152: 12147: 12142: 12137: 12132: 12127: 12122: 12117: 12112: 12107: 12102: 12097: 12092: 12087: 12082: 12077: 12072: 12067: 12062: 12057: 12052: 12047: 12042: 12040:Oxapium iodide 12037: 12032: 12027: 12022: 12017: 12012: 12007: 12002: 11997: 11992: 11987: 11982: 11980:Methylatropine 11977: 11972: 11967: 11962: 11957: 11952: 11947: 11942: 11937: 11932: 11927: 11922: 11912: 11907: 11902: 11897: 11892: 11887: 11882: 11877: 11872: 11854: 11849: 11844: 11839: 11834: 11829: 11824: 11819: 11814: 11809: 11804: 11799: 11794: 11789: 11784: 11779: 11774: 11769: 11764: 11759: 11754: 11749: 11744: 11742:Cyclopentolate 11739: 11734: 11729: 11724: 11719: 11714: 11709: 11704: 11699: 11694: 11689: 11684: 11679: 11674: 11669: 11664: 11659: 11654: 11649: 11644: 11639: 11634: 11629: 11624: 11586: 11581: 11576: 11571: 11520:dimenhydrinate 11516:cyproheptadine 11485: 11480: 11475: 11470: 11465: 11460: 11455: 11445: 11440: 11434: 11432: 11426: 11425: 11423: 11422: 11417: 11412: 11407: 11402: 11397: 11392: 11387: 11382: 11377: 11372: 11367: 11362: 11357: 11355:Sebacylcholine 11352: 11347: 11342: 11337: 11332: 11327: 11322: 11317: 11312: 11307: 11302: 11297: 11292: 11287: 11282: 11277: 11272: 11267: 11262: 11257: 11252: 11247: 11242: 11237: 11232: 11227: 11222: 11217: 11212: 11210:Butyrylcholine 11207: 11202: 11197: 11192: 11187: 11182: 11177: 11172: 11167: 11162: 11157: 11152: 11146: 11144: 11135: 11124: 11123: 11113: 11112: 11105: 11098: 11090: 11084: 11081: 11080: 11066: 11063: 11062: 11051: 11050: 11042: 11041:External links 11039: 11036: 11035: 11016:(3): 297–305. 10996: 10985:(11): 1751–5. 10969: 10942: 10923: 10903: 10876: 10841: 10784: 10733: 10676: 10635: 10605: 10588:Harvard Health 10574: 10540: 10509: 10459: 10424: 10385: 10378: 10360: 10358: 10357: 10351: 10335: 10329: 10304: 10298: 10281: 10275: 10246: 10240: 10206: 10199: 10173: 10138: 10100: 10067: 10017: 9992: 9960: 9958: 9957: 9937: 9914:Canada Gazette 9902: 9874: 9847: 9840: 9821: 9778: 9747: 9704: 9671: 9620: 9577: 9564: 9554: 9544: 9516: 9489: 9487: 9486: 9473: 9456: 9446:(9): 2967–72. 9425: 9376: 9365: 9345: 9304: 9283:(2): 197–203. 9263: 9214: 9170: 9124: 9083: 9064:(3): 199–214. 9047: 9040: 9021: 8994:(8): 698–704. 8978: 8951:(11): 819–28. 8935: 8908:(11): 2183–4. 8888: 8842: 8793: 8758:Anesthesiology 8744: 8703: 8661: 8618: 8569: 8540:(11): 1264–9. 8520: 8485:Anesthesiology 8468: 8419: 8390:(4): 1144–53. 8384:Anesthesiology 8359: 8310: 8271: 8213: 8169: 8126: 8077: 8034: 8007:Anesthesiology 7990: 7921: 7872: 7819: 7778:(March 2016). 7766: 7737:(8): 740–747. 7717: 7688:(3): 197–227. 7668: 7617: 7596:(5): 878–879. 7576: 7547:(4): 801–811. 7518: 7492: 7440: 7388: 7361:(9): 1059–77. 7342: 7298: 7262: 7221: 7192:(6): 1227–32. 7186:Anesthesiology 7172: 7137:Anesthesiology 7123: 7088: 7059:(3): 223–225. 7039: 6988: 6939: 6878: 6828: 6801:Pain Physician 6787: 6738: 6686: 6633: 6579: 6536: 6483: 6432: 6378: 6335: 6328: 6310: 6284: 6232: 6180: 6154: 6128: 6069: 6020:(5): 419–426. 5997: 5948: 5921:(5): 411–420. 5898: 5871:(4): 399–405. 5850: 5823:(1–2): 61–70. 5807: 5756: 5729:Pain Physician 5715: 5664: 5623: 5596: 5547: 5518:(5): 456–466. 5493: 5442: 5391: 5350: 5307: 5266: 5235: 5208:(9): 571–575. 5192: 5136: 5101: 5074:(5): 633–638. 5051: 5005: 4959: 4916: 4889:(12): 1081–7. 4873: 4838: 4798: 4766: 4738: 4711:Anesthesiology 4690: 4661:(5): 521–546. 4630: 4603:(9): 1059–77. 4587: 4548: 4519:(2): 181–192. 4496: 4467:(2): 113–125. 4440: 4389: 4341: 4312:(6): 864–871. 4292: 4246: 4225:(5): 449–461. 4200: 4171:(3): 621–660. 4140: 4058: 4051: 4025: 3992:Anesthesiology 3975: 3932: 3884: 3816: 3801: 3760: 3714: 3650: 3584: 3573: 3550: 3519: 3508: 3459: 3448:(3): 173–184. 3442:Pain Physician 3432: 3365: 3344: 3317: 3287: 3276: 3255: 3254: 3252: 3249: 3205: 3202: 3174: 3171: 3095:Main article: 3092: 3089: 3088: 3087: 3080: 3073:United Kingdom 3069: 3054: 3047: 3027: 3024: 3019:Main article: 3016: 3013: 2976: 2973: 2967: 2964: 2944:dextrorotation 2884: 2877: 2876: 2869: 2862: 2861: 2860: 2859: 2858: 2856: 2853: 2813: 2810: 2808: 2805: 2758:biotransformed 2714: 2711: 2689: 2686: 2681: 2650: 2646: 2641: 2633: 2599:animal studies 2589: 2575: 2521: 2520: 2516: 2515: 2513: 2510: 2507: 2504: 2501: 2498: 2492: 2491: 2489: 2486: 2483: 2480: 2477: 2474: 2463: 2462: 2460: 2457: 2454: 2451: 2448: 2445: 2434: 2433: 2431: 2428: 2425: 2422: 2419: 2416: 2405: 2404: 2402: 2399: 2394: 2391: 2388: 2385: 2374: 2373: 2371: 2368: 2365: 2362: 2359: 2356: 2352: 2347: 2346: 2344: 2341: 2338: 2335: 2332: 2329: 2325: 2321: 2316: 2315: 2313: 2310: 2307: 2304: 2301: 2298: 2294: 2290: 2285: 2284: 2282: 2279: 2276: 2273: 2270: 2267: 2263: 2259: 2254: 2253: 2251: 2248: 2245: 2242: 2239: 2236: 2232: 2228: 2223: 2222: 2220: 2217: 2214: 2211: 2208: 2205: 2197: 2193: 2187: 2186: 2184: 2181: 2178: 2175: 2172: 2169: 2161: 2157: 2151: 2150: 2148: 2145: 2140: 2137: 2134: 2131: 2127: 2122: 2121: 2118: 2115: 2108: 2105: 2100: 2097: 2092: 2088: 2083: 2082: 2080: 2077: 2072: 2069: 2066: 2063: 2059: 2054: 2053: 2050: 2047: 2042: 2039: 2034: 2031: 2026: 2015: 2014: 2012: 2009: 2006: 2003: 2000: 1997: 1989: 1983: 1982: 1980: 1977: 1974: 1971: 1968: 1965: 1954: 1953: 1951: 1948: 1945: 1942: 1939: 1936: 1925: 1924: 1921: 1918: 1915: 1912: 1905: 1899:below 100 μM) 1896: 1891: 1888: 1719: 1716: 1714: 1711: 1709: 1706: 1670: 1667: 1644: 1641: 1566:blood in urine 1550:kidney failure 1546:hydronephrosis 1537: 1534: 1505:benzodiazepine 1476: 1473: 1472: 1471: 1468: 1461: 1456: 1450: 1444: 1433: 1410: 1407: 1403:bronchodilator 1398: 1395: 1386: 1383: 1374: 1371: 1314:of ketamine – 1292:antidepressant 1281: 1278: 1236: 1233: 1126: 1123: 1121: 1118: 1090:hallucinogenic 1075:blood pressure 1031: 1030: 1019: 1018: 1016: 1015: 1012: 1010: 1007: 999: 998: 997: 994: 993: 991: 990: 987: 979: 978: 977: 974: 973: 970: 964: 963: 962: 961: 951: 935: 929: 928: 926: 925: 917: 915: 907: 906: 900: 894: 893: 881: 875: 870: 864: 863: 859: 858: 848: 840: 839: 837: 836: 823: 821: 808: 807: 805: 804: 796: 794: 788: 787: 785: 784: 776: 774: 768: 767: 765: 764: 756: 748: 746: 740: 739: 737: 736: 728: 726: 720: 719: 717: 716: 708: 706: 700: 699: 697: 696: 688: 686: 680: 679: 677: 676: 668: 666: 660: 659: 657: 656: 648: 646: 635: 634: 632: 631: 623: 621: 620: 613: 605: 597: 595: 589: 588: 586: 585: 578: 570: 569: 568: 565: 564: 560: 559: 558: 557: 551: 543: 537: 536: 535: 534: 531: 528: 523: 517: 516: 515: 514: 511: 506: 497: 496: 495: 494: 491: 488: 485: 482: 477: 471: 470: 469: 468: 463: 458: 451: 445: 444: 443: 442: 422: 416: 415: 412: 406: 405: 404: 403: 397: 391: 385: 379: 373: 367: 359: 353: 352: 345: 344: 342: 341: 338: 329: 317: 305: 293: 282: 269: 255: 253: 247: 246: 242: 241: 239: 238: 225: 223: 217: 216: 214:antidepressant 195: 189: 188: 185: 183:administration 177: 176: 173: 165: 164: 162: 161: 159: 149: 147: 139: 138: 136: 135: 118: 100: 98: 92: 91: 84: 74: 73: 70: 66: 65: 62: 56: 55: 51: 50: 42: 41: 15: 9: 6: 4: 3: 2: 38994: 38983: 38980: 38978: 38975: 38973: 38970: 38968: 38965: 38963: 38960: 38958: 38955: 38953: 38950: 38948: 38945: 38943: 38940: 38938: 38935: 38933: 38930: 38928: 38925: 38923: 38920: 38918: 38915: 38913: 38910: 38908: 38905: 38903: 38900: 38898: 38895: 38893: 38890: 38888: 38885: 38883: 38880: 38878: 38875: 38873: 38870: 38868: 38865: 38864: 38862: 38852: 38842: 38841: 38838: 38821: 38820: 38817: 38811: 38804: 38800: 38797: 38794: 38790: 38789:phencyclidine 38786: 38785:nitrous oxide 38782: 38781:methoxetamine 38778: 38774: 38770: 38767: 38764: 38760: 38756: 38753: 38750: 38746: 38742: 38738: 38734: 38731: 38728: 38724: 38723:dexamethasone 38720: 38717: 38715: 38711: 38707: 38704: 38701: 38697: 38693: 38689: 38685: 38681: 38677: 38673: 38669: 38666: 38659: 38656: 38652: 38648: 38645: 38642: 38638: 38634: 38630: 38626: 38623: 38620: 38616: 38613: 38610: 38606: 38602: 38598: 38595: 38588: 38585: 38581: 38578: 38577:AMPA receptor 38575: 38572: 38568: 38564: 38560: 38556: 38553: 38549: 38542: 38539: 38535: 38531: 38527: 38523: 38519: 38515: 38511: 38508: 38505: 38504: 38501: 38497: 38489: 38484: 38482: 38477: 38475: 38470: 38469: 38466: 38450: 38447: 38445: 38444:Prenoxdiazine 38442: 38440: 38437: 38435: 38432: 38430: 38427: 38426: 38424: 38420: 38414: 38411: 38409: 38406: 38404: 38401: 38400: 38398: 38396: 38392: 38386: 38383: 38381: 38378: 38376: 38373: 38371: 38368: 38366: 38363: 38361: 38358: 38356: 38353: 38351: 38348: 38346: 38343: 38341: 38338: 38336: 38333: 38331: 38328: 38326: 38323: 38321: 38318: 38316: 38313: 38311: 38308: 38306: 38303: 38301: 38298: 38296: 38293: 38291: 38288: 38286: 38283: 38281: 38278: 38276: 38273: 38271: 38268: 38266: 38263: 38261: 38258: 38256: 38253: 38251: 38248: 38246: 38245:Diprenorphine 38243: 38241: 38240:Cyprenorphine 38238: 38236: 38233: 38231: 38228: 38226: 38223: 38221: 38218: 38216: 38213: 38211: 38208: 38206: 38203: 38202: 38200: 38198: 38195: 38191: 38183: 38180: 38178: 38175: 38174: 38173: 38170: 38166: 38163: 38161: 38160:Diethyl ether 38158: 38157: 38156: 38153: 38149: 38146: 38145: 38144: 38141: 38137: 38134: 38132: 38129: 38127: 38124: 38122: 38119: 38118: 38117: 38114: 38113: 38111: 38107: 38101: 38097: 38091: 38088: 38086: 38083: 38081: 38078: 38075: 38074: 38069: 38066: 38064: 38063:Ibotenic acid 38061: 38059: 38056: 38054: 38051: 38050: 38048: 38044: 38037: 38029: 38025: 38021: 38017: 38013: 38009: 38005: 38001: 37991: 37988: 37986: 37983: 37981: 37978: 37976: 37973: 37971: 37968: 37966: 37963: 37961: 37958: 37956: 37953: 37951: 37948: 37946: 37943: 37941: 37938: 37936: 37933: 37931: 37930:Bromocriptine 37928: 37926: 37923: 37921: 37918: 37917: 37915: 37913: 37910: 37903: 37889: 37886: 37884: 37881: 37879: 37876: 37874: 37871: 37869: 37866: 37864: 37861: 37859: 37858:THC-O-acetate 37856: 37854: 37851: 37849: 37846: 37844: 37841: 37839: 37836: 37834: 37831: 37829: 37826: 37824: 37821: 37819: 37816: 37814: 37811: 37809: 37806: 37804: 37801: 37799: 37796: 37794: 37791: 37789: 37786: 37784: 37781: 37779: 37776: 37774: 37771: 37769: 37766: 37764: 37761: 37759: 37756: 37754: 37751: 37749: 37746: 37744: 37741: 37739: 37736: 37734: 37731: 37729: 37728:MDMB-FUBINACA 37726: 37724: 37723:MDMB-CHMINACA 37721: 37719: 37716: 37714: 37713:Levonantradol 37711: 37709: 37706: 37704: 37701: 37699: 37696: 37694: 37691: 37689: 37686: 37684: 37681: 37679: 37676: 37674: 37671: 37669: 37666: 37664: 37661: 37659: 37656: 37654: 37651: 37649: 37646: 37644: 37641: 37639: 37636: 37634: 37631: 37629: 37626: 37624: 37621: 37619: 37616: 37614: 37611: 37609: 37606: 37604: 37601: 37599: 37596: 37594: 37591: 37589: 37586: 37584: 37581: 37579: 37576: 37574: 37571: 37569: 37566: 37564: 37561: 37559: 37556: 37554: 37551: 37549: 37546: 37544: 37541: 37539: 37536: 37534: 37531: 37529: 37526: 37524: 37521: 37519: 37516: 37514: 37511: 37509: 37508:5F-ADB-PINACA 37506: 37504: 37501: 37499: 37496: 37494: 37493:5F-AB-FUPPYCA 37491: 37489: 37486: 37485: 37483: 37481: 37477: 37471: 37468: 37466: 37463: 37461: 37458: 37456: 37453: 37451: 37448: 37446: 37443: 37441: 37438: 37436: 37433: 37431: 37428: 37426: 37423: 37421: 37418: 37416: 37413: 37411: 37408: 37406: 37403: 37401: 37398: 37396: 37393: 37391: 37388: 37386: 37383: 37381: 37378: 37376: 37373: 37371: 37368: 37366: 37363: 37361: 37358: 37356: 37353: 37351: 37348: 37346: 37343: 37341: 37338: 37336: 37333: 37331: 37328: 37326: 37323: 37321: 37318: 37316: 37313: 37311: 37308: 37306: 37303: 37301: 37298: 37296: 37293: 37291: 37288: 37286: 37283: 37281: 37278: 37276: 37273: 37271: 37268: 37266: 37263: 37261: 37258: 37256: 37253: 37251: 37248: 37246: 37243: 37241: 37238: 37236: 37233: 37231: 37228: 37226: 37223: 37221: 37218: 37216: 37213: 37211: 37208: 37206: 37203: 37201: 37198: 37196: 37193: 37191: 37188: 37186: 37183: 37181: 37178: 37176: 37173: 37171: 37168: 37166: 37163: 37161: 37158: 37157: 37155: 37153: 37152: 37146: 37140: 37137: 37135: 37132: 37130: 37127: 37125: 37122: 37120: 37117: 37115: 37112: 37110: 37107: 37105: 37102: 37100: 37097: 37096: 37094: 37092: 37091: 37085: 37079: 37078:(-)-CP 55,940 37076: 37074: 37073:(+)-CP 55,940 37071: 37069: 37068:(±)-CP 55,940 37066: 37064: 37061: 37059: 37056: 37054: 37051: 37050: 37048: 37046: 37045: 37039: 37033: 37030: 37028: 37025: 37023: 37020: 37018: 37015: 37013: 37010: 37008: 37005: 37003: 37000: 36998: 36995: 36993: 36990: 36988: 36985: 36983: 36980: 36978: 36975: 36973: 36970: 36968: 36965: 36963: 36960: 36958: 36955: 36953: 36950: 36948: 36945: 36943: 36940: 36938: 36935: 36933: 36930: 36928: 36925: 36923: 36920: 36918: 36915: 36913: 36910: 36908: 36905: 36903: 36900: 36898: 36895: 36893: 36890: 36888: 36885: 36883: 36880: 36878: 36875: 36873: 36870: 36868: 36865: 36863: 36860: 36858: 36855: 36853: 36850: 36848: 36845: 36843: 36840: 36838: 36835: 36833: 36830: 36828: 36825: 36823: 36820: 36818: 36815: 36813: 36810: 36809: 36807: 36805: 36804: 36798: 36795: 36793: 36789: 36783: 36780: 36778: 36775: 36773: 36770: 36769: 36767: 36765: 36761: 36758: 36754: 36745: 36741: 36738: 36734: 36728: 36725: 36723: 36720: 36718: 36715: 36713: 36710: 36708: 36705: 36703: 36700: 36698: 36695: 36693: 36690: 36688: 36685: 36683: 36680: 36678: 36675: 36673: 36670: 36668: 36665: 36663: 36660: 36658: 36655: 36653: 36650: 36648: 36645: 36643: 36640: 36638: 36635: 36633: 36630: 36628: 36625: 36623: 36620: 36618: 36615: 36613: 36610: 36608: 36605: 36603: 36600: 36598: 36597:Dicycloverine 36595: 36593: 36590: 36588: 36585: 36583: 36580: 36578: 36575: 36573: 36570: 36568: 36565: 36563: 36560: 36558: 36555: 36553: 36550: 36548: 36545: 36543: 36540: 36538: 36535: 36533: 36530: 36528: 36525: 36523: 36520: 36518: 36515: 36513: 36510: 36508: 36505: 36503: 36500: 36498: 36495: 36493: 36490: 36489: 36487: 36483: 36479: 36473: 36469: 36459: 36456: 36454: 36451: 36449: 36446: 36444: 36441: 36439: 36436: 36434: 36431: 36429: 36428:Nitrous oxide 36426: 36424: 36421: 36419: 36416: 36414: 36411: 36409: 36406: 36404: 36401: 36399: 36396: 36394: 36391: 36389: 36386: 36384: 36381: 36379: 36376: 36374: 36371: 36369: 36366: 36364: 36361: 36359: 36356: 36355: 36353: 36349: 36343: 36340: 36338: 36335: 36333: 36330: 36328: 36325: 36323: 36320: 36319: 36317: 36315: 36311: 36305: 36302: 36300: 36299:Fluorolintane 36297: 36295: 36292: 36290: 36287: 36286: 36284: 36280: 36274: 36271: 36269: 36266: 36264: 36261: 36260: 36258: 36256: 36252: 36242: 36239: 36237: 36234: 36232: 36229: 36228: 36226: 36222: 36215: 36214:Tenocyclidine 36212: 36209: 36208:Rolicyclidine 36206: 36203: 36202:Phencyclidine 36200: 36198: 36195: 36192: 36189: 36186: 36183: 36181: 36178: 36176: 36173: 36171: 36168: 36166: 36163: 36161: 36158: 36156: 36153: 36151: 36148: 36146: 36143: 36141: 36138: 36136: 36133: 36132: 36130: 36126: 36120: 36117: 36115: 36112: 36110: 36107: 36105: 36102: 36100: 36097: 36095: 36094:Methoxetamine 36092: 36090: 36087: 36084: 36081: 36078: 36075: 36073: 36070: 36067: 36064: 36062: 36059: 36058: 36056: 36052: 36049: 36047: 36041: 36038: 36034: 36030: 36024: 36023:Dissociatives 36020: 36008: 36004: 36000: 35996: 35992: 35986: 35983: 35981: 35978: 35976: 35973: 35971: 35968: 35966: 35963: 35961: 35958: 35956: 35953: 35951: 35948: 35947: 35945: 35941: 35931: 35928: 35926: 35923: 35921: 35918: 35916: 35913: 35911: 35908: 35906: 35903: 35901: 35898: 35896: 35893: 35891: 35888: 35886: 35883: 35881: 35878: 35876: 35873: 35871: 35868: 35866: 35863: 35861: 35858: 35856: 35853: 35852: 35850: 35846: 35840: 35837: 35835: 35832: 35830: 35827: 35825: 35822: 35820: 35817: 35816: 35814: 35808: 35804: 35798: 35795: 35793: 35790: 35788: 35785: 35783: 35780: 35779: 35777: 35771: 35767: 35761: 35758: 35756: 35755:Tabernanthine 35753: 35751: 35748: 35746: 35743: 35741: 35738: 35736: 35733: 35731: 35728: 35726: 35723: 35721: 35718: 35717: 35715: 35711: 35705: 35702: 35700: 35697: 35695: 35692: 35690: 35687: 35686: 35684: 35678: 35674: 35668: 35665: 35663: 35660: 35658: 35657:Norbaeocystin 35655: 35653: 35650: 35648: 35645: 35643: 35640: 35638: 35635: 35633: 35631: 35627: 35622: 35620: 35617: 35615: 35612: 35610: 35608: 35604: 35599: 35597: 35595: 35591: 35586: 35584: 35581: 35579: 35576: 35574: 35571: 35569: 35566: 35564: 35561: 35559: 35556: 35554: 35551: 35549: 35546: 35544: 35541: 35540: 35538: 35532: 35528: 35522: 35519: 35517: 35514: 35512: 35509: 35507: 35504: 35503: 35501: 35495: 35491: 35485: 35482: 35480: 35477: 35475: 35472: 35470: 35467: 35465: 35462: 35461: 35459: 35453: 35449: 35443: 35440: 35438: 35435: 35433: 35430: 35428: 35425: 35424: 35422: 35416: 35412: 35406: 35403: 35401: 35398: 35396: 35393: 35391: 35388: 35386: 35383: 35382: 35380: 35378: 35376: 35371: 35368: 35366: 35362: 35356: 35353: 35351: 35348: 35346: 35343: 35342: 35340: 35338: 35334: 35324: 35321: 35319: 35316: 35314: 35311: 35309: 35306: 35304: 35301: 35299: 35296: 35294: 35291: 35289: 35286: 35284: 35281: 35279: 35276: 35274: 35271: 35269: 35266: 35264: 35261: 35259: 35256: 35254: 35251: 35249: 35246: 35244: 35241: 35239: 35236: 35234: 35231: 35229: 35226: 35224: 35223:2CB-5-hemifly 35221: 35219: 35216: 35214: 35211: 35209: 35206: 35204: 35201: 35200: 35198: 35194: 35187: 35184: 35181: 35178: 35175: 35172: 35171: 35169: 35167: 35163: 35157: 35154: 35152: 35149: 35147: 35144: 35142: 35139: 35137: 35134: 35132: 35129: 35127: 35124: 35122: 35119: 35117: 35116:Isoproscaline 35114: 35112: 35109: 35107: 35104: 35102: 35099: 35097: 35094: 35092: 35089: 35087: 35084: 35082: 35079: 35077: 35076:Asymbescaline 35074: 35072: 35071:Allylescaline 35069: 35067: 35064: 35062: 35059: 35057: 35054: 35052: 35049: 35047: 35044: 35043: 35041: 35037: 35031: 35028: 35026: 35023: 35021: 35018: 35016: 35013: 35011: 35008: 35006: 35003: 35001: 34998: 34996: 34993: 34991: 34988: 34986: 34983: 34981: 34978: 34977: 34975: 34973: 34970: 34966: 34960: 34957: 34955: 34952: 34950: 34947: 34946: 34944: 34942: 34937: 34931: 34928: 34926: 34923: 34921: 34918: 34916: 34913: 34911: 34908: 34906: 34903: 34901: 34898: 34896: 34893: 34891: 34888: 34886: 34883: 34881: 34878: 34876: 34873: 34871: 34868: 34867: 34865: 34863: 34862: 34856: 34850: 34847: 34845: 34842: 34840: 34837: 34835: 34832: 34830: 34827: 34825: 34822: 34820: 34817: 34815: 34812: 34811: 34809: 34807: 34802: 34796: 34793: 34791: 34788: 34786: 34783: 34781: 34778: 34776: 34773: 34771: 34768: 34767: 34765: 34763: 34758: 34748: 34745: 34743: 34740: 34738: 34735: 34733: 34730: 34728: 34725: 34723: 34720: 34718: 34715: 34713: 34710: 34708: 34705: 34703: 34700: 34698: 34695: 34693: 34690: 34688: 34685: 34683: 34680: 34678: 34675: 34674: 34672: 34670: 34666: 34660: 34657: 34655: 34652: 34650: 34647: 34645: 34642: 34640: 34637: 34635: 34632: 34630: 34627: 34625: 34622: 34620: 34617: 34615: 34612: 34610: 34607: 34605: 34602: 34601: 34599: 34597: 34593: 34588: 34578: 34575: 34573: 34570: 34568: 34565: 34563: 34560: 34558: 34555: 34553: 34550: 34548: 34545: 34543: 34540: 34538: 34535: 34533: 34530: 34528: 34525: 34523: 34520: 34518: 34515: 34513: 34510: 34508: 34505: 34503: 34500: 34498: 34495: 34493: 34490: 34488: 34485: 34483: 34480: 34478: 34475: 34473: 34470: 34468: 34465: 34463: 34460: 34458: 34455: 34453: 34450: 34448: 34445: 34443: 34440: 34438: 34435: 34434: 34432: 34428: 34422: 34419: 34417: 34414: 34412: 34409: 34407: 34404: 34402: 34399: 34397: 34394: 34392: 34389: 34387: 34384: 34382: 34379: 34377: 34374: 34372: 34369: 34367: 34364: 34362: 34359: 34357: 34354: 34352: 34349: 34347: 34344: 34342: 34339: 34338: 34336: 34330: 34325: 34319: 34316: 34314: 34311: 34309: 34306: 34304: 34301: 34299: 34296: 34294: 34291: 34289: 34286: 34284: 34281: 34279: 34276: 34274: 34271: 34269: 34266: 34264: 34261: 34260: 34258: 34252: 34247: 34241: 34238: 34236: 34233: 34231: 34228: 34226: 34223: 34221: 34218: 34216: 34213: 34211: 34208: 34206: 34203: 34201: 34198: 34196: 34193: 34191: 34188: 34187: 34185: 34179: 34174: 34168: 34165: 34163: 34160: 34158: 34155: 34153: 34150: 34148: 34145: 34143: 34140: 34138: 34135: 34133: 34130: 34128: 34125: 34123: 34120: 34119: 34117: 34111: 34106: 34100: 34097: 34095: 34092: 34090: 34087: 34085: 34082: 34080: 34077: 34075: 34072: 34070: 34067: 34065: 34062: 34060: 34057: 34055: 34052: 34050: 34047: 34045: 34042: 34041: 34039: 34033: 34028: 34022: 34019: 34017: 34014: 34012: 34009: 34007: 34004: 34002: 33999: 33997: 33994: 33992: 33989: 33987: 33984: 33982: 33979: 33977: 33974: 33972: 33969: 33967: 33964: 33963: 33961: 33955: 33950: 33944: 33941: 33939: 33936: 33935: 33933: 33927: 33922: 33919: 33917: 33916: 33912: 33906: 33900: 33897: 33895: 33892: 33890: 33887: 33885: 33882: 33880: 33877: 33875: 33872: 33870: 33867: 33865: 33862: 33860: 33857: 33855: 33852: 33850: 33847: 33845: 33842: 33840: 33837: 33835: 33832: 33830: 33827: 33825: 33822: 33820: 33817: 33815: 33812: 33810: 33807: 33805: 33802: 33800: 33797: 33795: 33792: 33790: 33787: 33785: 33782: 33780: 33777: 33775: 33772: 33770: 33767: 33765: 33762: 33760: 33757: 33755: 33752: 33750: 33747: 33745: 33742: 33740: 33737: 33735: 33732: 33730: 33727: 33725: 33722: 33720: 33717: 33715: 33712: 33710: 33707: 33705: 33702: 33700: 33697: 33695: 33692: 33690: 33687: 33685: 33682: 33680: 33677: 33675: 33672: 33670: 33667: 33665: 33662: 33660: 33657: 33655: 33652: 33650: 33647: 33645: 33642: 33640: 33637: 33635: 33632: 33630: 33627: 33625: 33622: 33620: 33617: 33615: 33612: 33610: 33607: 33605: 33602: 33600: 33597: 33595: 33592: 33590: 33587: 33585: 33582: 33580: 33577: 33576: 33574: 33572: 33571: 33565: 33562: 33560: 33554: 33548: 33545: 33543: 33540: 33538: 33535: 33533: 33530: 33528: 33525: 33523: 33520: 33518: 33515: 33513: 33510: 33508: 33505: 33503: 33500: 33498: 33495: 33493: 33490: 33488: 33485: 33483: 33480: 33478: 33475: 33473: 33470: 33468: 33465: 33463: 33460: 33458: 33455: 33453: 33450: 33448: 33445: 33443: 33440: 33438: 33435: 33433: 33430: 33428: 33425: 33423: 33420: 33418: 33415: 33413: 33410: 33408: 33405: 33403: 33400: 33398: 33395: 33393: 33390: 33388: 33385: 33384: 33382: 33380: 33374: 33368: 33365: 33363: 33360: 33358: 33355: 33353: 33350: 33348: 33345: 33343: 33340: 33338: 33335: 33333: 33330: 33329: 33327: 33325: 33321: 33318: 33313: 33304: 33300: 33296: 33295:Hallucinogens 33289: 33284: 33282: 33277: 33275: 33270: 33269: 33266: 33246: 33243: 33241: 33238: 33234: 33231: 33229: 33226: 33225: 33223: 33221: 33218: 33216: 33213: 33212: 33210: 33206:Countries by 33204: 33198: 33195: 33193: 33190: 33188: 33185: 33183: 33180: 33178: 33175: 33173: 33170: 33168: 33165: 33163: 33160: 33158: 33155: 33153: 33150: 33148: 33147:Drug checking 33145: 33144: 33142: 33138: 33129: 33128: 33127: 33124: 33122: 33119: 33117: 33116:Neurotoxicity 33114: 33112: 33109: 33107: 33104: 33102: 33099: 33095: 33092: 33091: 33090: 33087: 33085: 33082: 33080: 33077: 33075: 33072: 33070: 33067: 33065: 33062: 33061: 33059: 33053: 33041: 33038: 33036: 33033: 33031: 33030:Cannabis shop 33028: 33026: 33023: 33022: 33021: 33018: 33016: 33013: 33009: 33006: 33004: 33003:United States 33001: 32999: 32996: 32994: 32991: 32989: 32986: 32984: 32981: 32979: 32976: 32974: 32971: 32969: 32966: 32964: 32961: 32959: 32956: 32954: 32951: 32949: 32946: 32944: 32941: 32939: 32936: 32934: 32931: 32929: 32926: 32924: 32921: 32919: 32916: 32914: 32911: 32909: 32906: 32904: 32901: 32899: 32896: 32894: 32891: 32889: 32886: 32884: 32881: 32879: 32876: 32874: 32871: 32869: 32866: 32864: 32861: 32859: 32858:Latin America 32856: 32854: 32851: 32849: 32846: 32844: 32841: 32839: 32836: 32834: 32831: 32829: 32826: 32824: 32821: 32819: 32816: 32814: 32811: 32809: 32806: 32804: 32801: 32799: 32796: 32794: 32791: 32789: 32786: 32784: 32781: 32779: 32776: 32774: 32771: 32769: 32766: 32764: 32761: 32759: 32756: 32754: 32751: 32749: 32746: 32744: 32741: 32739: 32736: 32734: 32731: 32729: 32726: 32724: 32721: 32719: 32716: 32714: 32711: 32709: 32706: 32704: 32701: 32699: 32696: 32694: 32691: 32690: 32689: 32686: 32685: 32683: 32679: 32673: 32670: 32668: 32665: 32663: 32660: 32658: 32655: 32654: 32652: 32646: 32643: 32635: 32631: 32624: 32620: 32606: 32603: 32599: 32596: 32594: 32593:Plan Colombia 32591: 32589: 32586: 32585: 32584: 32581: 32579: 32576: 32574: 32571: 32569: 32566: 32564: 32561: 32559: 32556: 32554: 32553:Designer drug 32551: 32549: 32546: 32544: 32541: 32539: 32536: 32534: 32531: 32530: 32528: 32524: 32518: 32515: 32513: 32510: 32508: 32505: 32503: 32500: 32498: 32495: 32493: 32490: 32488: 32485: 32483: 32480: 32479: 32477: 32475:Drug legality 32473: 32465: 32462: 32460: 32457: 32455: 32452: 32450: 32447: 32445: 32442: 32440: 32437: 32435: 32432: 32430: 32427: 32426: 32425: 32424:United States 32422: 32420: 32417: 32415: 32412: 32410: 32407: 32405: 32402: 32400: 32397: 32395: 32392: 32390: 32387: 32385: 32382: 32380: 32377: 32375: 32372: 32370: 32367: 32366: 32364: 32358: 32350: 32347: 32345: 32342: 32338: 32337:Latin America 32335: 32334: 32333: 32330: 32328: 32325: 32323: 32320: 32318: 32315: 32313: 32310: 32309: 32308: 32307:Policy reform 32305: 32301: 32298: 32296: 32293: 32291: 32288: 32286: 32283: 32281: 32278: 32277: 32276: 32273: 32272: 32270: 32266: 32258: 32255: 32253: 32250: 32248: 32245: 32244: 32242: 32238: 32235: 32233: 32230: 32228: 32225: 32224: 32223: 32220: 32219: 32217: 32215:International 32213: 32209: 32202: 32198: 32184: 32181: 32179: 32176: 32174: 32173:Sex and drugs 32171: 32169: 32166: 32164: 32161: 32159: 32156: 32154: 32153:Poly drug use 32151: 32149: 32146: 32144: 32141: 32139: 32136: 32134: 32131: 32129: 32126: 32124: 32121: 32119: 32116: 32114: 32111: 32109: 32106: 32104: 32101: 32099: 32096: 32095: 32093: 32089: 32083: 32080: 32078: 32075: 32073: 32070: 32068: 32065: 32063: 32062:Cloud-chasing 32060: 32058: 32055: 32053: 32050: 32049: 32047: 32045: 32041: 32035: 32032: 32030: 32027: 32025: 32022: 32020: 32017: 32015: 32012: 32010: 32007: 32005: 32002: 32000: 31997: 31995: 31992: 31990: 31989:Psychonautics 31987: 31986: 31984: 31982: 31978: 31972: 31969: 31967: 31964: 31962: 31959: 31957: 31954: 31952: 31949: 31947: 31944: 31942: 31939: 31937: 31934: 31932: 31929: 31927: 31924: 31922: 31919: 31917: 31916:Drinking song 31914: 31912: 31909: 31907: 31906:Diethyl ether 31904: 31902: 31899: 31897: 31896:Beer festival 31894: 31892: 31889: 31887: 31884: 31883: 31881: 31879: 31875: 31869: 31866: 31864: 31861: 31859: 31856: 31854: 31851: 31850: 31848: 31846: 31842: 31836: 31833: 31831: 31828: 31826: 31823: 31821: 31818: 31816: 31813: 31811: 31808: 31806: 31803: 31801: 31798: 31796: 31793: 31791: 31788: 31786: 31783: 31781: 31778: 31776: 31773: 31771: 31768: 31766: 31763: 31761: 31758: 31756: 31753: 31751: 31748: 31746: 31743: 31742: 31740: 31738: 31734: 31730: 31726: 31721: 31717: 31703: 31700: 31697: 31693: 31692:Nitrous oxide 31690: 31686: 31683: 31681: 31678: 31677: 31676: 31673: 31671: 31668: 31666: 31663: 31662: 31660: 31658: 31654: 31644: 31641: 31639: 31636: 31635: 31633: 31631: 31627: 31619: 31616: 31614: 31611: 31609: 31606: 31604: 31601: 31600: 31599: 31596: 31592: 31589: 31587: 31584: 31582: 31579: 31578: 31577: 31574: 31573: 31571: 31569: 31565: 31559: 31556: 31554: 31551: 31547: 31544: 31542: 31539: 31537: 31534: 31532: 31529: 31528: 31527: 31523: 31520: 31519: 31517: 31515: 31511: 31503: 31500: 31499: 31498: 31495: 31493: 31490: 31486: 31483: 31482: 31481: 31478: 31476: 31473: 31471: 31468: 31464: 31461: 31459: 31456: 31454: 31451: 31448: 31444: 31443:Nitrous oxide 31441: 31440: 31439: 31436: 31434: 31431: 31428: 31424: 31421: 31420: 31418: 31416: 31415:Dissociatives 31412: 31404: 31401: 31400: 31399: 31395: 31392: 31388: 31385: 31383: 31380: 31378: 31375: 31374: 31373: 31370: 31368: 31365: 31363: 31360: 31356: 31353: 31352: 31351: 31348: 31344: 31341: 31339: 31336: 31334: 31331: 31330: 31329: 31326: 31325: 31323: 31321: 31317: 31314: 31312: 31311:Hallucinogens 31308: 31300: 31297: 31295: 31292: 31291: 31290: 31287: 31285: 31282: 31280: 31277: 31272: 31271: 31270: 31267: 31265: 31262: 31261: 31259: 31257: 31253: 31245: 31242: 31240: 31237: 31236: 31235: 31232: 31228: 31225: 31223: 31220: 31218: 31215: 31214: 31213: 31210: 31208: 31205: 31203: 31200: 31198: 31195: 31193: 31190: 31188: 31185: 31183: 31180: 31176: 31173: 31172: 31171: 31168: 31164: 31161: 31159: 31156: 31155: 31154: 31151: 31147: 31144: 31143: 31142: 31139: 31135: 31132: 31130: 31129:Energy drinks 31127: 31125: 31122: 31121: 31120: 31117: 31115: 31112: 31108: 31105: 31104: 31103: 31100: 31098: 31095: 31094: 31092: 31090: 31086: 31080: 31077: 31073: 31070: 31069: 31068: 31065: 31061: 31058: 31057: 31056: 31053: 31049: 31046: 31045: 31044: 31041: 31039: 31036: 31031: 31030: 31029: 31028:Hydromorphone 31026: 31024: 31021: 31016: 31015: 31014: 31011: 31009: 31006: 31001: 30998: 30997: 30996: 30993: 30988: 30987: 30986: 30983: 30979: 30976: 30975: 30974: 30971: 30966: 30963: 30962: 30961: 30960:Buprenorphine 30958: 30957: 30955: 30953: 30949: 30943: 30940: 30938: 30935: 30933: 30930: 30924: 30921: 30920: 30918: 30914: 30913:Paint thinner 30911: 30909: 30906: 30904: 30901: 30899: 30896: 30895: 30894: 30890: 30885: 30881: 30880:Nitrous oxide 30878: 30877: 30875: 30874: 30873: 30870: 30868: 30865: 30863: 30860: 30856: 30853: 30851: 30848: 30846: 30843: 30842: 30841: 30838: 30836: 30833: 30831: 30828: 30826: 30823: 30822: 30820: 30818: 30814: 30810: 30803: 30799: 30795: 30788: 30783: 30781: 30776: 30774: 30769: 30768: 30765: 30759: 30755: 30750: 30728: 30726: 30723: 30722: 30720: 30717: 30714: 30711: 30709: 30706: 30705: 30701: 30691: 30688: 30686: 30683: 30681: 30674: 30672: 30670: 30666: 30663: 30659: 30655: 30654:neurosteroids 30652: 30649: 30647: 30640: 30639: 30636: 30632:Miscellaneous 30629: 30625: 30610: 30609:levothyroxine 30602: 30598: 30595: 30592: 30588: 30584: 30581: 30579: 30576: 30573: 30569: 30565: 30561: 30557: 30556:brexpiprazole 30553: 30549: 30546: 30545: 30542: 30538: 30533: 30529: 30515: 30512: 30511:Irreversible: 30509: 30508: 30506: 30500: 30491: 30485: 30482: 30480: 30477: 30475: 30472: 30470: 30467: 30465: 30462: 30460: 30457: 30455: 30452: 30449: 30448: 30446: 30440: 30431: 30425: 30422: 30419: 30418: 30415: 30412: 30409: 30408: 30405: 30402: 30400: 30397: 30395: 30392: 30390: 30387: 30385: 30382: 30380: 30377: 30375: 30372: 30370: 30367: 30365: 30362: 30360: 30357: 30355: 30352: 30350: 30347: 30345: 30344:Isocarboxazid 30342: 30340: 30337: 30335: 30332: 30330: 30327: 30326:Irreversible: 30324: 30323: 30321: 30319:Non-selective 30317: 30313: 30309: 30304: 30300: 30286: 30283: 30282: 30280: 30276: 30270: 30267: 30265: 30262: 30260: 30257: 30255: 30252: 30251: 30249: 30244: 30238: 30232: 30229: 30227: 30224: 30222: 30219: 30217: 30216:Protriptyline 30214: 30212: 30209: 30207: 30204: 30202: 30199: 30197: 30194: 30192: 30191:Nortriptyline 30189: 30187: 30186:Nitroxazepine 30184: 30182: 30179: 30177: 30174: 30172: 30169: 30167: 30164: 30162: 30159: 30157: 30154: 30152: 30149: 30147: 30144: 30142: 30139: 30137: 30134: 30132: 30129: 30127: 30126:Demexiptiline 30124: 30122: 30119: 30117: 30114: 30112: 30109: 30107: 30104: 30102: 30101:Amitriptyline 30099: 30097: 30094: 30093: 30091: 30086: 30080: 30076: 30072: 30068: 30063: 30059: 30045: 30042: 30040: 30037: 30035: 30032: 30030: 30027: 30025: 30022: 30020: 30017: 30015: 30012: 30010: 30007: 30005: 30002: 30000: 29997: 29995: 29992: 29990: 29987: 29985: 29982: 29980: 29977: 29975: 29972: 29970: 29967: 29966: 29964: 29960: 29954: 29951: 29949: 29946: 29945: 29943: 29938: 29932: 29926: 29923: 29921: 29918: 29916: 29913: 29912: 29910: 29905: 29899: 29893: 29890: 29888: 29885: 29883: 29880: 29879: 29877: 29872: 29866: 29860: 29857: 29855: 29852: 29850: 29847: 29846: 29844: 29839: 29833: 29827: 29824: 29822: 29819: 29817: 29814: 29813: 29811: 29806: 29800: 29794: 29791: 29789: 29786: 29784: 29781: 29779: 29776: 29774: 29771: 29769: 29766: 29765: 29763: 29758: 29752: 29746: 29743: 29741: 29738: 29736: 29733: 29731: 29728: 29726: 29723: 29721: 29718: 29716: 29713: 29711: 29708: 29707: 29705: 29700: 29694: 29690: 29686: 29682: 29676: 29672: 29667: 29663: 29656: 29651: 29649: 29644: 29642: 29637: 29636: 29633: 29617: 29615: 29612: 29611: 29609: 29606: 29603: 29600: 29598: 29595: 29594: 29590: 29584: 29581: 29579: 29576: 29574: 29571: 29569: 29566: 29564: 29561: 29559: 29556: 29554: 29551: 29549: 29546: 29544: 29541: 29539: 29536: 29534: 29531: 29529: 29526: 29524: 29521: 29519: 29516: 29515: 29513: 29509: 29503: 29500: 29498: 29497:Methocarbamol 29495: 29493: 29492:Mephenoxalone 29490: 29488: 29485: 29483: 29482:Chlorzoxazone 29480: 29478: 29475: 29474: 29472: 29470: 29466: 29456: 29453: 29452: 29450: 29448: 29444: 29438: 29435: 29433: 29430: 29428: 29425: 29418: 29417: 29413: 29412:amitriptyline 29409: 29406: 29404: 29401: 29399: 29396: 29393: 29389: 29385: 29382: 29380: 29377: 29375: 29374:Carbamazepine 29372: 29371: 29369: 29367: 29363: 29357: 29354: 29352: 29349: 29347: 29344: 29342: 29339: 29337: 29334: 29332: 29329: 29327: 29324: 29323: 29321: 29319: 29315: 29312: 29310: 29304: 29298: 29295: 29293: 29290: 29288: 29285: 29283: 29280: 29278: 29275: 29274: 29272: 29270: 29266: 29256: 29253: 29251: 29248: 29246: 29243: 29241: 29238: 29236: 29233: 29231: 29228: 29227: 29225: 29221: 29214: 29207: 29204: 29202: 29199: 29197: 29194: 29192: 29189: 29187: 29184: 29182: 29179: 29178: 29176: 29174: 29170: 29163: 29156: 29153: 29151: 29148: 29146: 29143: 29141: 29138: 29136: 29133: 29131: 29128: 29126: 29123: 29121: 29118: 29116: 29113: 29111: 29108: 29106: 29103: 29101: 29098: 29096: 29093: 29091: 29088: 29086: 29083: 29081: 29078: 29076: 29073: 29070: 29066: 29063: 29062: 29060: 29058: 29054: 29048: 29045: 29043: 29040: 29038: 29035: 29033: 29030: 29029: 29027: 29025: 29021: 29015: 29012: 29010: 29007: 29005: 29002: 29000: 28997: 28995: 28992: 28989: 28982: 28979: 28978: 28976: 28974: 28970: 28964: 28961: 28959: 28956: 28954: 28951: 28949: 28946: 28943: 28936: 28933: 28931: 28928: 28926: 28923: 28921: 28918: 28916: 28913: 28912: 28910: 28906: 28900: 28897: 28895: 28892: 28890: 28887: 28885: 28882: 28880: 28877: 28876: 28874: 28870: 28864: 28861: 28859: 28856: 28854: 28851: 28849: 28846: 28844: 28841: 28839: 28836: 28833: 28832:Dexketoprofen 28826: 28823: 28820: 28812: 28805: 28802: 28800: 28797: 28795: 28792: 28790: 28787: 28786: 28784: 28780: 28777: 28775: 28771: 28765: 28762: 28760: 28757: 28755: 28752: 28748: 28745: 28743: 28740: 28738: 28735: 28733: 28730: 28728: 28725: 28723: 28720: 28718: 28715: 28713: 28710: 28709: 28708: 28705: 28703: 28700: 28698: 28695: 28693: 28690: 28689: 28687: 28684: 28680: 28670: 28667: 28664: 28660: 28653: 28650: 28648: 28645: 28643: 28640: 28638: 28635: 28633: 28630: 28628: 28625: 28623: 28620: 28618: 28615: 28613: 28610: 28608: 28607:Phenoperidine 28605: 28603: 28600: 28598: 28595: 28593: 28590: 28588: 28585: 28583: 28580: 28578: 28575: 28573: 28570: 28568: 28565: 28563: 28560: 28558: 28555: 28553: 28550: 28547: 28543: 28540: 28538: 28537:Ethoheptazine 28535: 28533: 28530: 28528: 28525: 28523: 28520: 28518: 28515: 28513: 28510: 28508: 28505: 28503: 28500: 28498: 28495: 28493: 28490: 28488: 28485: 28484: 28482: 28478: 28472: 28469: 28467: 28464: 28462: 28459: 28456: 28452: 28448: 28444: 28440: 28433: 28430: 28428: 28425: 28423: 28420: 28418: 28415: 28413: 28410: 28408: 28405: 28403: 28400: 28398: 28397:Hydromorphone 28395: 28393: 28390: 28387: 28383: 28379: 28372: 28369: 28367: 28366:Ethylmorphine 28364: 28362: 28359: 28357: 28354: 28351: 28344: 28341: 28339: 28336: 28334: 28331: 28329: 28326: 28323: 28316: 28315:Buprenorphine 28313: 28311: 28308: 28306: 28303: 28302: 28300: 28298:Semisynthetic 28296: 28290: 28287: 28285: 28282: 28280: 28277: 28274: 28270: 28267: 28263: 28260: 28258: 28255: 28254: 28253: 28250: 28249: 28247: 28245: 28241: 28237: 28234: 28232: 28228: 28223: 28219: 28215: 28208: 28203: 28201: 28196: 28194: 28189: 28188: 28185: 28169: 28167: 28164: 28163: 28161: 28158: 28155: 28152: 28150: 28147: 28146: 28142: 28132: 28129: 28127: 28124: 28123: 28121: 28117: 28111: 28108: 28106: 28103: 28101: 28098: 28097: 28095: 28093: 28089: 28083: 28080: 28078: 28077:Phencyclidine 28075: 28073: 28070: 28068: 28065: 28064: 28062: 28060: 28056: 28050: 28047: 28044: 28041: 28039: 28038:Phenoperidine 28036: 28034: 28031: 28029: 28026: 28024: 28021: 28019: 28016: 28014: 28011: 28009: 28006: 28005: 28003: 28001: 27997: 27991: 27988: 27986: 27983: 27981: 27978: 27976: 27973: 27972: 27970: 27968: 27964: 27958: 27955: 27953: 27950: 27948: 27945: 27943: 27942:Narcobarbital 27940: 27938: 27935: 27933: 27930: 27928: 27925: 27924: 27922: 27920: 27916: 27910: 27907: 27905: 27902: 27900: 27897: 27896: 27894: 27892: 27888: 27885: 27883: 27879: 27873: 27870: 27868: 27865: 27863: 27860: 27858: 27855: 27853: 27852:Nitrous oxide 27850: 27848: 27845: 27843: 27840: 27838: 27835: 27833: 27830: 27828: 27825: 27823: 27820: 27818: 27815: 27813: 27812:Diethyl ether 27810: 27808: 27805: 27803: 27800: 27798: 27795: 27794: 27792: 27790: 27786: 27781: 27777: 27770: 27765: 27763: 27758: 27756: 27751: 27750: 27747: 27741: 27737: 27732: 27716: 27715: 27712: 27706: 27700: 27697: 27695: 27692: 27690: 27687: 27685: 27682: 27680: 27677: 27675: 27672: 27670: 27667: 27665: 27662: 27660: 27657: 27655: 27652: 27650: 27647: 27645: 27642: 27640: 27637: 27635: 27632: 27630: 27627: 27624: 27620: 27617: 27615: 27612: 27610: 27607: 27605: 27602: 27600: 27597: 27595: 27592: 27590: 27587: 27585: 27582: 27580: 27577: 27575: 27572: 27570: 27567: 27565: 27562: 27560: 27557: 27554: 27553: 27550: 27547: 27544: 27543: 27540: 27537: 27535: 27532: 27530: 27527: 27525: 27522: 27520: 27517: 27515: 27512: 27510: 27507: 27505: 27502: 27500: 27497: 27495: 27492: 27490: 27487: 27485: 27482: 27479: 27478: 27475: 27474:Tenocyclidine 27472: 27470: 27467: 27465: 27462: 27460: 27457: 27455: 27452: 27450: 27447: 27445: 27442: 27439: 27438: 27436: 27432: 27426: 27423: 27421: 27418: 27416: 27413: 27408: 27403: 27401: 27398: 27396: 27393: 27391: 27388: 27386: 27383: 27381: 27378: 27376: 27373: 27371: 27368: 27363: 27358: 27353: 27348: 27346: 27343: 27341: 27338: 27336: 27333: 27331: 27328: 27326: 27323: 27321: 27318: 27315: 27314: 27311: 27308: 27306: 27303: 27301: 27298: 27296: 27293: 27291: 27288: 27286: 27283: 27281: 27278: 27276: 27273: 27271: 27268: 27265: 27264: 27261: 27258: 27256: 27253: 27251: 27250:Phencyclidine 27248: 27246: 27243: 27241: 27238: 27236: 27233: 27231: 27228: 27226: 27220: 27218: 27215: 27213: 27210: 27208: 27205: 27203: 27200: 27198: 27195: 27193: 27190: 27188: 27185: 27183: 27180: 27178: 27175: 27173: 27170: 27167: 27166: 27164: 27162: 27155: 27149: 27146: 27144: 27141: 27139: 27136: 27134: 27131: 27129: 27126: 27124: 27121: 27119: 27116: 27114: 27111: 27109: 27106: 27104: 27101: 27099: 27096: 27094: 27091: 27089: 27086: 27084: 27081: 27079: 27076: 27071: 27066: 27061: 27056: 27054: 27048: 27046: 27043: 27041: 27038: 27036: 27033: 27031: 27028: 27026: 27023: 27021: 27020:Amitriptyline 27018: 27016: 27013: 27011: 27008: 27006: 27003: 27001: 26998: 26996: 26993: 26991: 26988: 26986: 26983: 26981: 26978: 26975: 26974: 26971: 26968: 26966: 26963: 26959: 26956: 26953: 26952: 26949: 26946: 26944: 26941: 26939: 26936: 26934: 26931: 26929: 26926: 26924: 26921: 26919: 26916: 26914: 26911: 26909: 26906: 26904: 26901: 26899: 26896: 26894: 26891: 26889: 26886: 26884: 26881: 26879: 26876: 26874: 26871: 26869: 26866: 26864: 26861: 26859: 26856: 26854: 26851: 26849: 26846: 26844: 26841: 26839: 26836: 26834: 26831: 26829: 26826: 26824: 26821: 26818: 26817: 26814: 26811: 26809: 26806: 26804: 26801: 26799: 26796: 26794: 26791: 26789: 26786: 26784: 26781: 26779: 26776: 26774: 26771: 26769: 26766: 26764: 26761: 26759: 26756: 26754: 26751: 26749: 26746: 26744: 26741: 26739: 26736: 26734: 26733:Methoxetamine 26731: 26729: 26726: 26724: 26721: 26719: 26713: 26711: 26708: 26706: 26703: 26701: 26698: 26696: 26693: 26691: 26688: 26686: 26683: 26681: 26678: 26676: 26673: 26671: 26668: 26666: 26663: 26661: 26658: 26656: 26653: 26651: 26648: 26646: 26643: 26641: 26638: 26636: 26633: 26631: 26628: 26625: 26621: 26618: 26615: 26611: 26608: 26606: 26603: 26601: 26598: 26596: 26593: 26591: 26588: 26583: 26578: 26576: 26573: 26571: 26568: 26566: 26563: 26561: 26558: 26556: 26553: 26551: 26548: 26546: 26543: 26541: 26538: 26536: 26533: 26531: 26528: 26526: 26523: 26520: 26519: 26517: 26515: 26508: 26504: 26501: 26494: 26489: 26487: 26482: 26480: 26475: 26474: 26471: 26458: 26455: 26452: 26451: 26448: 26445: 26443: 26442:Pronociceptin 26440: 26438: 26437:Proenkephalin 26435: 26433: 26430: 26428: 26425: 26422: 26421: 26418: 26415: 26413: 26410: 26408: 26405: 26403: 26400: 26398: 26395: 26393: 26390: 26388: 26385: 26383: 26380: 26378: 26375: 26373: 26370: 26368: 26365: 26363: 26360: 26358: 26355: 26353: 26350: 26348: 26342: 26340: 26337: 26335: 26332: 26330: 26327: 26325: 26321: 26320: 26318: 26314: 26304: 26301: 26299: 26296: 26294: 26291: 26289: 26286: 26284: 26281: 26279: 26276: 26274: 26271: 26269: 26266: 26264: 26261: 26259: 26256: 26254: 26251: 26249: 26246: 26244: 26241: 26239: 26233: 26232: 26230: 26226: 26220: 26217: 26215: 26212: 26210: 26207: 26205: 26202: 26200: 26197: 26195: 26192: 26190: 26187: 26185: 26182: 26180: 26177: 26175: 26172: 26170: 26167: 26165: 26159: 26157: 26154: 26152: 26149: 26147: 26144: 26142: 26139: 26137: 26134: 26132: 26129: 26127: 26124: 26122: 26119: 26117: 26114: 26112: 26109: 26107: 26104: 26102: 26099: 26097: 26096:Buprenorphine 26094: 26092: 26089: 26087: 26081: 26079: 26073: 26071: 26061: 26059: 26053: 26051: 26048: 26047: 26045: 26041: 26038: 26034: 26030: 26020: 26017: 26015: 26012: 26010: 26007: 26005: 26002: 26000: 25997: 25995: 25992: 25990: 25987: 25985: 25982: 25980: 25977: 25975: 25972: 25970: 25967: 25965: 25962: 25960: 25957: 25955: 25952: 25950: 25947: 25945: 25942: 25940: 25937: 25935: 25932: 25930: 25927: 25925: 25922: 25920: 25917: 25915: 25912: 25910: 25907: 25905: 25902: 25900: 25897: 25895: 25892: 25890: 25887: 25885: 25882: 25880: 25877: 25875: 25872: 25870: 25867: 25865: 25862: 25860: 25857: 25855: 25852: 25850: 25847: 25845: 25842: 25840: 25837: 25835: 25832: 25830: 25829:Buprenorphine 25827: 25825: 25822: 25820: 25817: 25815: 25812: 25810: 25807: 25805: 25802: 25800: 25797: 25795: 25792: 25790: 25787: 25785: 25782: 25780: 25779:Amentoflavone 25777: 25775: 25772: 25770: 25767: 25765: 25762: 25760: 25757: 25755: 25752: 25750: 25747: 25745: 25742: 25740: 25737: 25736: 25734: 25730: 25724: 25721: 25719: 25716: 25714: 25711: 25709: 25706: 25703: 25702:nortriptyline 25699: 25695: 25691: 25690:amitriptyline 25687: 25684: 25682: 25679: 25677: 25674: 25672: 25669: 25667: 25664: 25662: 25659: 25657: 25654: 25652: 25649: 25646: 25642: 25639: 25637: 25634: 25632: 25629: 25627: 25624: 25622: 25619: 25617: 25614: 25612: 25609: 25607: 25604: 25602: 25599: 25597: 25594: 25592: 25589: 25587: 25584: 25582: 25579: 25577: 25574: 25572: 25569: 25567: 25564: 25562: 25559: 25557: 25554: 25552: 25549: 25547: 25544: 25542: 25539: 25537: 25534: 25532: 25529: 25527: 25524: 25522: 25519: 25517: 25514: 25512: 25509: 25507: 25504: 25502: 25499: 25497: 25494: 25492: 25489: 25487: 25484: 25482: 25479: 25477: 25474: 25472: 25469: 25467: 25464: 25462: 25459: 25457: 25454: 25452: 25449: 25447: 25444: 25442: 25439: 25437: 25434: 25432: 25429: 25427: 25424: 25422: 25419: 25417: 25414: 25412: 25409: 25407: 25404: 25402: 25399: 25397: 25396:Hydromorphone 25394: 25392: 25389: 25387: 25384: 25382: 25379: 25377: 25374: 25372: 25369: 25367: 25364: 25362: 25359: 25357: 25354: 25352: 25349: 25347: 25344: 25342: 25339: 25337: 25334: 25332: 25329: 25327: 25324: 25322: 25319: 25317: 25314: 25312: 25311:Diprenorphine 25309: 25307: 25304: 25302: 25299: 25297: 25294: 25292: 25291:Difelikefalin 25289: 25287: 25284: 25282: 25279: 25277: 25274: 25272: 25271:Cyprenorphine 25269: 25267: 25264: 25262: 25259: 25257: 25254: 25252: 25249: 25247: 25244: 25242: 25239: 25237: 25234: 25232: 25229: 25227: 25224: 25222: 25219: 25217: 25216:Big dynorphin 25214: 25212: 25209: 25207: 25204: 25202: 25199: 25197: 25194: 25192: 25189: 25187: 25184: 25182: 25179: 25177: 25174: 25172: 25169: 25167: 25164: 25162: 25159: 25157: 25154: 25152: 25149: 25147: 25144: 25142: 25139: 25137: 25136:3CS-nalmefene 25134: 25133: 25131: 25127: 25124: 25120: 25116: 25106: 25103: 25101: 25098: 25096: 25093: 25091: 25088: 25086: 25083: 25081: 25078: 25076: 25073: 25071: 25068: 25066: 25063: 25061: 25058: 25056: 25053: 25051: 25048: 25046: 25043: 25041: 25038: 25036: 25033: 25031: 25028: 25026: 25023: 25021: 25018: 25016: 25013: 25011: 25008: 25006: 25003: 25001: 24998: 24996: 24993: 24991: 24988: 24986: 24983: 24981: 24980:Diprenorphine 24978: 24976: 24973: 24971: 24968: 24966: 24963: 24961: 24958: 24956: 24953: 24951: 24948: 24946: 24943: 24941: 24938: 24936: 24933: 24931: 24928: 24926: 24923: 24921: 24918: 24916: 24913: 24911: 24908: 24906: 24903: 24902: 24900: 24896: 24890: 24887: 24885: 24882: 24880: 24877: 24875: 24872: 24870: 24867: 24865: 24862: 24860: 24857: 24855: 24852: 24850: 24847: 24845: 24842: 24840: 24837: 24835: 24832: 24830: 24827: 24825: 24822: 24820: 24817: 24815: 24812: 24810: 24807: 24805: 24802: 24800: 24797: 24795: 24792: 24790: 24787: 24785: 24782: 24780: 24777: 24775: 24772: 24770: 24767: 24765: 24762: 24760: 24757: 24755: 24752: 24750: 24747: 24745: 24742: 24740: 24737: 24735: 24732: 24730: 24727: 24725: 24722: 24720: 24717: 24715: 24712: 24710: 24707: 24705: 24702: 24700: 24697: 24695: 24692: 24690: 24687: 24685: 24684:Hydromorphone 24682: 24680: 24677: 24675: 24672: 24670: 24667: 24665: 24662: 24660: 24657: 24655: 24652: 24650: 24647: 24645: 24642: 24640: 24637: 24635: 24632: 24630: 24627: 24625: 24622: 24620: 24617: 24615: 24612: 24610: 24607: 24605: 24602: 24600: 24597: 24595: 24594:Deltorphin II 24592: 24590: 24587: 24585: 24582: 24580: 24577: 24575: 24572: 24570: 24567: 24565: 24562: 24560: 24557: 24555: 24552: 24550: 24547: 24545: 24542: 24540: 24537: 24535: 24532: 24530: 24527: 24525: 24522: 24520: 24517: 24515: 24512: 24510: 24507: 24505: 24502: 24500: 24497: 24495: 24492: 24490: 24487: 24485: 24482: 24480: 24479:3CS-nalmefene 24477: 24476: 24474: 24470: 24467: 24463: 24459: 24449: 24446: 24444: 24441: 24439: 24436: 24434: 24431: 24429: 24426: 24424: 24421: 24419: 24416: 24414: 24411: 24409: 24406: 24404: 24401: 24399: 24396: 24394: 24391: 24389: 24386: 24384: 24381: 24379: 24376: 24374: 24371: 24369: 24366: 24364: 24361: 24359: 24356: 24354: 24351: 24349: 24346: 24344: 24341: 24339: 24336: 24334: 24331: 24329: 24328:Methocinnamox 24326: 24324: 24321: 24319: 24316: 24314: 24311: 24309: 24306: 24304: 24301: 24299: 24296: 24294: 24291: 24289: 24288:Ginsenoside R 24286: 24284: 24281: 24279: 24276: 24274: 24271: 24269: 24266: 24264: 24261: 24259: 24258:Diprenorphine 24256: 24254: 24251: 24249: 24246: 24244: 24241: 24239: 24236: 24233: 24231: 24228: 24226: 24223: 24221: 24218: 24216: 24213: 24211: 24208: 24206: 24203: 24201: 24198: 24196: 24193: 24191: 24188: 24186: 24183: 24181: 24178: 24176: 24173: 24171: 24168: 24166: 24163: 24161: 24158: 24156: 24153: 24151: 24148: 24146: 24143: 24141: 24138: 24136: 24135:3CS-nalmefene 24133: 24131: 24128: 24126: 24123: 24122: 24120: 24116: 24110: 24107: 24105: 24102: 24100: 24097: 24095: 24092: 24090: 24087: 24085: 24082: 24080: 24077: 24075: 24072: 24070: 24067: 24065: 24062: 24060: 24057: 24055: 24052: 24050: 24047: 24045: 24042: 24040: 24037: 24035: 24032: 24030: 24027: 24025: 24022: 24020: 24017: 24015: 24012: 24010: 24007: 24005: 24002: 24000: 23997: 23995: 23992: 23990: 23987: 23985: 23982: 23980: 23977: 23975: 23972: 23970: 23967: 23965: 23964:Phencyclidine 23962: 23960: 23957: 23955: 23952: 23950: 23947: 23945: 23942: 23939: 23935: 23934: 23930: 23928: 23925: 23923: 23920: 23918: 23915: 23913: 23910: 23908: 23907:Oxymorphazone 23905: 23903: 23900: 23898: 23895: 23893: 23890: 23888: 23885: 23883: 23880: 23878: 23875: 23873: 23870: 23868: 23865: 23863: 23860: 23858: 23855: 23853: 23850: 23848: 23845: 23843: 23840: 23838: 23835: 23833: 23830: 23828: 23825: 23823: 23820: 23818: 23815: 23813: 23810: 23808: 23805: 23803: 23800: 23798: 23795: 23793: 23790: 23788: 23785: 23783: 23780: 23778: 23775: 23773: 23770: 23768: 23765: 23763: 23760: 23758: 23755: 23753: 23750: 23748: 23745: 23743: 23740: 23738: 23735: 23733: 23730: 23728: 23725: 23723: 23720: 23718: 23715: 23713: 23710: 23708: 23705: 23703: 23700: 23698: 23697:Hydromorphone 23695: 23693: 23690: 23688: 23685: 23683: 23680: 23678: 23675: 23673: 23670: 23668: 23665: 23663: 23660: 23658: 23655: 23653: 23650: 23648: 23645: 23643: 23642:Ethylmorphine 23640: 23638: 23635: 23633: 23632:Endomorphin-2 23630: 23628: 23627:Endomorphin-1 23625: 23623: 23620: 23618: 23615: 23613: 23610: 23608: 23607:Diphenoxylate 23605: 23603: 23600: 23598: 23595: 23593: 23590: 23588: 23585: 23583: 23580: 23578: 23575: 23573: 23570: 23568: 23565: 23563: 23560: 23558: 23555: 23553: 23550: 23548: 23545: 23543: 23540: 23538: 23535: 23533: 23530: 23528: 23525: 23523: 23520: 23518: 23515: 23513: 23510: 23508: 23505: 23503: 23500: 23498: 23495: 23493: 23492:Butyrfentanyl 23490: 23488: 23485: 23483: 23480: 23478: 23477:Buprenorphine 23475: 23473: 23470: 23468: 23465: 23463: 23460: 23458: 23455: 23453: 23450: 23448: 23445: 23443: 23440: 23438: 23435: 23433: 23430: 23428: 23425: 23423: 23420: 23418: 23415: 23413: 23410: 23408: 23405: 23403: 23400: 23398: 23395: 23393: 23392:Acrylfentanyl 23390: 23388: 23385: 23383: 23380: 23378: 23375: 23373: 23370: 23368: 23367:ψ-Akuammigine 23365: 23363: 23360: 23358: 23355: 23353: 23350: 23349: 23347: 23344: 23336: 23333: 23329: 23325: 23321: 23318: 23311: 23306: 23304: 23299: 23297: 23292: 23291: 23288: 23277: 23276: 23272: 23268: 23267:Serotonergics 23264: 23263:Dopaminergics 23260: 23256: 23252: 23249: 23242: 23236: 23233: 23229: 23226: 23224: 23221: 23220:Agonist-like: 23218: 23215: 23214: 23211: 23208: 23205: 23204: 23202: 23198: 23192: 23189: 23187: 23184: 23182: 23181:Tetrabenazine 23179: 23177: 23174: 23172: 23169: 23167: 23164: 23162: 23159: 23157: 23154: 23152: 23149: 23147: 23144: 23142: 23139: 23137: 23134: 23132: 23129: 23127: 23124: 23122: 23119: 23117: 23114: 23112: 23109: 23107: 23104: 23101: 23097: 23093: 23089: 23086: 23084: 23081: 23080: 23078: 23073: 23067: 23057: 23054: 23051: 23047: 23043: 23039: 23035: 23031: 23027: 23024: 23022: 23019: 23017: 23014: 23012: 23009: 23007: 23004: 23002: 22999: 22997: 22994: 22992: 22989: 22987: 22984: 22982: 22979: 22977: 22974: 22972: 22969: 22966: 22965:phencyclidine 22962: 22961:methoxetamine 22958: 22954: 22950: 22946: 22943: 22940: 22936: 22932: 22929: 22926: 22922: 22918: 22914: 22910: 22906: 22902: 22898: 22895: 22893: 22890: 22888: 22885: 22882: 22881: 22878: 22872: 22871:Protriptyline 22869: 22867: 22864: 22862: 22861:Nortriptyline 22859: 22857: 22854: 22852: 22849: 22847: 22844: 22842: 22839: 22837: 22834: 22832: 22829: 22827: 22824: 22822: 22819: 22817: 22816:Amitriptyline 22814: 22811: 22810: 22807: 22800: 22796: 22793: 22791: 22788: 22786: 22783: 22781: 22780:Tedatioxetine 22778: 22776: 22773: 22771: 22768: 22766: 22763: 22761: 22758: 22756: 22753: 22751: 22748: 22746: 22743: 22741: 22738: 22736: 22733: 22731: 22728: 22726: 22723: 22721: 22718: 22716: 22713: 22711: 22708: 22706: 22703: 22701: 22698: 22696: 22693: 22691: 22688: 22686: 22683: 22681: 22678: 22676: 22673: 22671: 22668: 22666: 22663: 22661: 22658: 22656: 22653: 22651: 22648: 22646: 22643: 22641: 22640:Centanafadine 22638: 22636: 22633: 22631: 22628: 22626: 22623: 22621: 22618: 22616: 22613: 22610: 22609: 22606: 22600: 22597: 22595: 22592: 22590: 22587: 22585: 22584:N-Methyl-PPPA 22582: 22580: 22577: 22575: 22572: 22570: 22567: 22565: 22562: 22560: 22557: 22555: 22552: 22550: 22547: 22545: 22542: 22540: 22537: 22534: 22533: 22530: 22524: 22521: 22519: 22516: 22514: 22511: 22509: 22506: 22504: 22501: 22499: 22496: 22494: 22491: 22489: 22486: 22484: 22481: 22479: 22476: 22473: 22472: 22469: 22466: 22464: 22461: 22459: 22456: 22454: 22451: 22449: 22446: 22444: 22441: 22439: 22436: 22434: 22431: 22429: 22426: 22424: 22423:Norfluoxetine 22421: 22419: 22416: 22414: 22411: 22409: 22406: 22404: 22401: 22399: 22396: 22394: 22391: 22389: 22386: 22384: 22381: 22379: 22376: 22374: 22371: 22369: 22366: 22364: 22363:Centpropazine 22361: 22359: 22356: 22354: 22351: 22348: 22347: 22344: 22341: 22334: 22323: 22317: 22306: 22302: 22298: 22294: 22290: 22286: 22285:desmetramadol 22282: 22279: 22277: 22274: 22272: 22269: 22267: 22266: 22265:Ginkgo biloba 22262: 22260: 22257: 22255: 22252: 22249: 22248:phencyclidine 22245: 22241: 22238: 22235: 22231: 22227: 22224: 22221: 22217: 22213: 22209: 22205: 22202: 22199: 22198: 22195: 22189: 22186: 22184: 22181: 22179: 22176: 22174: 22171: 22169: 22166: 22163: 22162: 22159: 22153: 22150: 22148: 22147:Protriptyline 22145: 22143: 22142:Nortriptyline 22140: 22138: 22135: 22133: 22130: 22128: 22125: 22123: 22120: 22118: 22115: 22113: 22110: 22108: 22105: 22103: 22100: 22098: 22095: 22093: 22092:Amitriptyline 22090: 22087: 22086: 22083: 22076: 22072: 22069: 22067: 22064: 22062: 22059: 22057: 22056:Tedatioxetine 22054: 22052: 22049: 22047: 22044: 22042: 22039: 22037: 22034: 22032: 22029: 22027: 22024: 22022: 22019: 22017: 22014: 22012: 22009: 22007: 22004: 22002: 21999: 21997: 21994: 21992: 21989: 21987: 21984: 21982: 21979: 21977: 21974: 21972: 21969: 21967: 21964: 21962: 21959: 21957: 21954: 21952: 21949: 21947: 21944: 21942: 21939: 21937: 21934: 21932: 21929: 21927: 21924: 21922: 21919: 21917: 21916:Centanafadine 21914: 21912: 21909: 21907: 21904: 21902: 21899: 21897: 21894: 21892: 21889: 21886: 21885: 21882: 21876: 21873: 21871: 21868: 21866: 21863: 21861: 21858: 21856: 21855:N-Methyl-PPPA 21853: 21851: 21848: 21846: 21843: 21841: 21838: 21836: 21833: 21831: 21828: 21826: 21823: 21821: 21818: 21816: 21813: 21810: 21809: 21806: 21800: 21797: 21795: 21792: 21790: 21787: 21785: 21782: 21780: 21777: 21775: 21772: 21770: 21767: 21765: 21762: 21760: 21757: 21755: 21752: 21750: 21747: 21745: 21742: 21740: 21737: 21735: 21732: 21730: 21727: 21724: 21723: 21720: 21714: 21711: 21709: 21706: 21704: 21701: 21699: 21696: 21694: 21691: 21689: 21686: 21684: 21681: 21679: 21676: 21674: 21671: 21669: 21666: 21664: 21661: 21659: 21656: 21654: 21651: 21649: 21646: 21644: 21641: 21638: 21637: 21634: 21631: 21624: 21613: 21607: 21597: 21594: 21592: 21589: 21587: 21584: 21582: 21581:Tedatioxetine 21579: 21577: 21574: 21572: 21569: 21567: 21564: 21562: 21559: 21557: 21554: 21552: 21549: 21547: 21544: 21542: 21539: 21537: 21534: 21532: 21529: 21527: 21524: 21522: 21519: 21517: 21514: 21512: 21509: 21507: 21504: 21502: 21499: 21497: 21494: 21492: 21489: 21487: 21484: 21482: 21479: 21477: 21474: 21472: 21469: 21467: 21464: 21462: 21459: 21457: 21454: 21452: 21449: 21447: 21444: 21442: 21439: 21437: 21434: 21432: 21429: 21427: 21424: 21422: 21419: 21417: 21414: 21412: 21409: 21407: 21404: 21402: 21399: 21397: 21394: 21392: 21389: 21387: 21384: 21382: 21379: 21377: 21374: 21372: 21369: 21367: 21364: 21362: 21359: 21357: 21354: 21352: 21349: 21347: 21346: 21342: 21340: 21337: 21335: 21332: 21330: 21327: 21325: 21322: 21320: 21317: 21315: 21312: 21310: 21307: 21305: 21302: 21300: 21297: 21294: 21293: 21290: 21284: 21281: 21279: 21276: 21274: 21271: 21269: 21266: 21264: 21261: 21259: 21256: 21254: 21251: 21249: 21246: 21244: 21241: 21239: 21236: 21234: 21231: 21229: 21226: 21224: 21221: 21219: 21216: 21214: 21211: 21209: 21206: 21204: 21203:Ioflupane (I) 21201: 21199: 21196: 21194: 21191: 21189: 21186: 21184: 21181: 21179: 21176: 21174: 21171: 21169: 21166: 21164: 21161: 21159: 21156: 21154: 21151: 21148: 21147: 21144: 21138: 21135: 21133: 21130: 21128: 21125: 21123: 21120: 21118: 21115: 21114:Pyrrolidines: 21112: 21111: 21108: 21102: 21101:Tenocyclidine 21099: 21097: 21094: 21092: 21089: 21087: 21086:Phencyclidine 21084: 21082: 21079: 21077: 21074: 21072: 21069: 21067: 21064: 21062: 21059: 21057: 21054: 21052: 21049: 21047: 21044: 21042: 21039: 21036: 21035: 21032: 21026: 21023: 21021: 21018: 21016: 21013: 21011: 21008: 21006: 21003: 21001: 20998: 20996: 20993: 20991: 20988: 20985: 20984: 20981: 20978: 20971: 20960: 20954: 20950: 20943: 20938: 20936: 20931: 20929: 20924: 20923: 20920: 20908: 20907: 20903: 20901: 20900: 20896: 20894: 20893: 20890: 20886: 20885: 20882: 20876: 20873: 20870: 20867: 20866: 20862: 20858: 20857:Transcrocetin 20855: 20853: 20852:Psychotridine 20850: 20848: 20845: 20843: 20840: 20838: 20835: 20833: 20832:Niflumic acid 20830: 20828: 20825: 20823: 20820: 20818: 20815: 20813: 20810: 20808: 20805: 20803: 20800: 20798: 20795: 20793: 20790: 20788: 20785: 20783: 20780: 20778: 20775: 20773: 20770: 20768: 20762: 20760: 20757: 20755: 20752: 20750: 20747: 20745: 20742: 20738: 20735: 20733: 20730: 20728: 20725: 20723: 20720: 20718: 20715: 20713: 20710: 20708: 20705: 20703: 20700: 20698: 20695: 20693: 20692:Nitrous oxide 20690: 20688: 20685: 20683: 20680: 20678: 20675: 20673: 20670: 20668: 20665: 20663: 20660: 20658: 20657:Diethyl ether 20655: 20653: 20650: 20648: 20645: 20643: 20640: 20638: 20635: 20633: 20630: 20626: 20623: 20621: 20618: 20616: 20613: 20609: 20606: 20604: 20601: 20599: 20596: 20594: 20591: 20587: 20584: 20582: 20579: 20577: 20574: 20572: 20569: 20567: 20564: 20562: 20559: 20557: 20554: 20552: 20549: 20547: 20544: 20542: 20539: 20537: 20534: 20532: 20529: 20527: 20523: 20520: 20518: 20515: 20513: 20512:Tenocyclidine 20510: 20508: 20507:Tabernanthine 20505: 20503: 20500: 20498: 20497:Rolicyclidine 20495: 20493: 20490: 20488: 20485: 20483: 20480: 20478: 20475: 20473: 20472:Phencyclidine 20470: 20468: 20467:Phencyclamine 20465: 20463: 20460: 20458: 20455: 20453: 20450: 20448: 20445: 20443: 20440: 20438: 20435: 20433: 20430: 20428: 20425: 20423: 20420: 20418: 20415: 20413: 20410: 20408: 20405: 20403: 20402:Methoxetamine 20400: 20398: 20395: 20393: 20390: 20388: 20385: 20383: 20380: 20378: 20375: 20373: 20370: 20368: 20365: 20363: 20362:Levomethadone 20360: 20358: 20355: 20353: 20350: 20348: 20345: 20343: 20340: 20338: 20335: 20333: 20330: 20328: 20325: 20323: 20322:Fluorolintane 20320: 20318: 20315: 20313: 20310: 20308: 20305: 20303: 20300: 20298: 20295: 20293: 20290: 20288: 20285: 20283: 20280: 20278: 20275: 20273: 20270: 20268: 20265: 20263: 20260: 20258: 20255: 20253: 20250: 20248: 20245: 20243: 20240: 20238: 20235: 20233: 20230: 20228: 20225: 20223: 20220: 20218: 20215: 20213: 20210: 20208: 20205: 20203: 20200: 20198: 20195: 20193: 20190: 20188: 20185: 20183: 20180: 20178: 20175: 20173: 20170: 20168: 20165: 20163: 20160: 20158: 20155: 20151: 20148: 20146: 20143: 20141: 20138: 20136: 20133: 20131: 20128: 20126: 20123: 20119: 20116: 20114: 20111: 20109: 20106: 20104: 20101: 20099: 20096: 20094: 20091: 20089: 20086: 20084: 20081: 20079: 20076: 20074: 20071: 20069: 20066: 20064: 20061: 20059: 20056: 20054: 20051: 20049: 20046: 20044: 20041: 20039: 20036: 20034: 20028: 20026: 20023: 20021: 20018: 20016: 20013: 20011: 20008: 20006: 20003: 20001: 19998: 19996: 19993: 19991: 19988: 19986: 19983: 19981: 19978: 19976: 19973: 19969: 19966: 19964: 19961: 19959: 19956: 19954: 19951: 19949: 19946: 19944: 19941: 19939: 19936: 19934: 19931: 19929: 19926: 19924: 19921: 19919: 19916: 19914: 19911: 19909: 19906: 19904: 19903:Kaitocephalin 19901: 19899: 19896: 19894: 19891: 19889: 19886: 19884: 19881: 19879: 19876: 19874: 19871: 19869: 19866: 19864: 19861: 19858: 19855: 19854: 19851: 19848: 19846: 19843: 19841: 19838: 19836: 19833: 19831: 19828: 19826: 19823: 19820: 19816: 19810: 19807: 19800: 19795: 19793: 19791: 19786: 19782: 19779: 19777: 19774: 19772: 19769: 19765: 19762: 19760: 19757: 19755: 19752: 19750: 19747: 19745: 19739: 19737: 19731: 19729: 19726: 19724: 19721: 19719: 19716: 19714: 19711: 19709: 19706: 19704: 19698: 19696: 19690: 19688: 19682: 19680: 19677: 19675: 19672: 19670: 19667: 19665: 19662: 19660: 19657: 19655: 19652: 19650: 19647: 19645: 19638: 19634: 19631: 19629: 19626: 19624: 19621: 19619: 19616: 19614: 19611: 19609: 19608:Ibotenic acid 19606: 19604: 19601: 19599: 19592: 19590: 19587: 19585: 19582: 19580: 19577: 19574: 19571: 19570: 19568: 19563: 19557: 19551: 19548: 19546: 19543: 19541: 19538: 19536: 19533: 19531: 19528: 19525: 19521: 19520:pentobarbital 19517: 19514: 19510: 19507: 19505: 19502: 19500: 19497: 19495: 19492: 19490: 19487: 19485: 19482: 19480: 19477: 19475: 19472: 19470: 19467: 19465: 19462: 19460: 19459:Kaitocephalin 19457: 19455: 19452: 19450: 19447: 19445: 19442: 19440: 19437: 19435: 19432: 19429: 19428: 19425: 19422: 19420: 19417: 19415: 19412: 19410: 19407: 19405: 19404:Cyclothiazide 19402: 19398: 19395: 19393: 19390: 19388: 19385: 19383: 19380: 19378: 19375: 19373: 19372:Ibotenic acid 19370: 19368: 19365: 19363: 19360: 19358: 19355: 19353: 19350: 19348: 19345: 19343: 19340: 19338: 19335: 19332: 19329: 19328: 19326: 19321: 19315: 19309: 19306: 19302: 19299: 19297: 19294: 19292: 19289: 19287: 19284: 19282: 19279: 19277: 19274: 19272: 19269: 19267: 19264: 19262: 19259: 19257: 19254: 19252: 19249: 19247: 19244: 19242: 19239: 19236: 19232: 19231:pentobarbital 19228: 19225: 19221: 19218: 19216: 19213: 19211: 19208: 19206: 19203: 19201: 19198: 19196: 19193: 19191: 19188: 19186: 19183: 19181: 19178: 19176: 19173: 19171: 19168: 19166: 19165:Kaitocephalin 19163: 19161: 19158: 19156: 19153: 19151: 19148: 19146: 19143: 19141: 19138: 19136: 19133: 19131: 19128: 19126: 19123: 19121: 19118: 19115: 19114: 19111: 19108: 19106: 19103: 19101: 19098: 19096: 19093: 19091: 19088: 19086: 19083: 19081: 19078: 19076: 19073: 19071: 19068: 19066: 19063: 19061: 19058: 19056: 19053: 19051: 19048: 19046: 19043: 19041: 19038: 19036: 19033: 19031: 19028: 19026: 19023: 19021: 19018: 19016: 19013: 19011: 19008: 19006: 19003: 19001: 18998: 18996: 18993: 18991: 18988: 18986: 18985:Cyclothiazide 18983: 18981: 18978: 18974: 18971: 18969: 18966: 18964: 18961: 18959: 18958:Ibotenic acid 18956: 18954: 18951: 18949: 18946: 18944: 18941: 18939: 18936: 18934: 18931: 18929: 18926: 18923: 18920: 18919: 18917: 18912: 18906: 18902: 18899: 18892: 18887: 18885: 18880: 18878: 18873: 18872: 18869: 18859: 18858: 18854: 18851: 18845: 18834: 18830: 18829: 18827: 18822: 18816: 18809: 18805: 18804: 18802: 18797: 18791: 18788: 18784: 18770: 18767: 18765: 18762: 18760: 18757: 18755: 18754:Niflumic acid 18752: 18750: 18747: 18745: 18742: 18740: 18737: 18735: 18732: 18730: 18727: 18726: 18724: 18722: 18718: 18715: 18711: 18701: 18698: 18696: 18693: 18691: 18688: 18686: 18683: 18681: 18678: 18676: 18673: 18672: 18670: 18668: 18664: 18658: 18655: 18653: 18650: 18648: 18647:Glibenclamide 18645: 18644: 18642: 18640: 18636: 18633: 18628: 18622: 18612: 18609: 18608: 18606: 18604: 18600: 18594: 18593:Niflumic acid 18591: 18589: 18586: 18584: 18581: 18579: 18578:Glibenclamide 18576: 18574: 18571: 18569: 18566: 18564: 18561: 18559: 18556: 18554: 18551: 18549: 18546: 18545: 18543: 18541: 18537: 18534: 18529: 18523: 18520: 18518: 18514: 18500: 18497: 18495: 18492: 18490: 18487: 18485: 18482: 18480: 18477: 18476: 18474: 18472: 18468: 18465: 18460: 18454: 18444: 18441: 18440: 18438: 18436: 18432: 18426: 18423: 18421: 18418: 18416: 18413: 18412: 18410: 18408: 18404: 18401: 18396: 18390: 18380: 18377: 18375: 18374:Grayanotoxins 18372: 18370: 18367: 18365: 18364:Batrachotoxin 18362: 18359: 18355: 18351: 18350:ω-Atracotoxin 18347: 18345: 18342: 18341: 18339: 18337: 18333: 18327: 18324: 18322: 18319: 18316: 18312: 18309: 18307: 18304: 18302: 18301:Buprenorphine 18299: 18296: 18295: 18292: 18289: 18287: 18284: 18282: 18279: 18277: 18274: 18272: 18269: 18266: 18265: 18262: 18259: 18257: 18254: 18252: 18249: 18247: 18244: 18242: 18239: 18237: 18234: 18232: 18229: 18227: 18224: 18222: 18219: 18217: 18214: 18211: 18210: 18207: 18204: 18202: 18199: 18197: 18194: 18192: 18189: 18187: 18184: 18182: 18179: 18177: 18174: 18172: 18169: 18167: 18164: 18162: 18159: 18157: 18154: 18152: 18149: 18147: 18144: 18142: 18139: 18137: 18134: 18132: 18129: 18127: 18124: 18122: 18119: 18117: 18114: 18112: 18109: 18107: 18104: 18102: 18099: 18097: 18094: 18092: 18089: 18086: 18082: 18078: 18075: 18073: 18070: 18068: 18065: 18063: 18060: 18058: 18056: 18052: 18049: 18048: 18045: 18042: 18040: 18037: 18035: 18034:Valproic acid 18032: 18030: 18027: 18025: 18022: 18020: 18017: 18015: 18012: 18010: 18007: 18005: 18002: 18000: 17997: 17995: 17992: 17990: 17987: 17985: 17982: 17980: 17979:Oxitriptyline 17977: 17975: 17974:Oxcarbazepine 17972: 17970: 17967: 17965: 17964:Licarbazepine 17962: 17960: 17957: 17955: 17952: 17950: 17947: 17945: 17942: 17940: 17937: 17935: 17932: 17930: 17927: 17925: 17922: 17920: 17919:Carbamazepine 17917: 17915: 17912: 17909: 17908: 17905: 17902: 17900: 17897: 17895: 17892: 17890: 17887: 17885: 17882: 17880: 17877: 17875: 17872: 17870: 17867: 17865: 17862: 17860: 17857: 17855: 17852: 17850: 17847: 17845: 17842: 17840: 17837: 17835: 17832: 17830: 17827: 17825: 17822: 17820: 17817: 17814: 17813: 17810: 17807: 17806:Antianginals: 17804: 17803: 17801: 17799: 17795: 17792: 17787: 17781: 17778: 17776: 17772: 17758: 17755: 17754: 17752: 17750: 17746: 17740: 17739:Norfluoxetine 17737: 17735: 17732: 17730: 17727: 17725: 17722: 17721: 17719: 17717: 17713: 17710: 17705: 17699: 17689: 17686: 17684: 17681: 17679: 17676: 17674: 17673:Niflumic acid 17671: 17669: 17666: 17664: 17661: 17659: 17652: 17651: 17649: 17647: 17643: 17637: 17634: 17632: 17629: 17627: 17620: 17619: 17617: 17615: 17611: 17608: 17603: 17594: 17584: 17581: 17576: 17570: 17569: 17566: 17563: 17561: 17558: 17556: 17553: 17551: 17548: 17546: 17543: 17541: 17538: 17536: 17533: 17531: 17528: 17526: 17525:Levcromakalim 17523: 17521: 17518: 17516: 17513: 17511: 17508: 17506: 17503: 17501: 17498: 17493: 17484: 17483: 17481: 17479: 17475: 17469: 17466: 17464: 17461: 17459: 17456: 17454: 17451: 17449: 17446: 17444: 17441: 17439: 17436: 17434: 17431: 17429: 17426: 17421: 17415: 17414: 17411: 17408: 17406: 17403: 17401: 17398: 17396: 17393: 17391: 17388: 17386: 17383: 17381: 17378: 17376: 17373: 17371: 17368: 17366: 17363: 17361: 17358: 17356: 17353: 17351: 17348: 17346: 17343: 17341: 17338: 17336: 17333: 17331: 17328: 17326: 17323: 17321: 17320:Acetohexamide 17318: 17313: 17304: 17303: 17301: 17299: 17295: 17292: 17287: 17281: 17271: 17268: 17266: 17263: 17261: 17253: 17252: 17250: 17248: 17244: 17238: 17235: 17233: 17230: 17228: 17225: 17223: 17215: 17214: 17211: 17208: 17206: 17203: 17201: 17198: 17196: 17193: 17191: 17188: 17186: 17183: 17181: 17178: 17176: 17173: 17171: 17168: 17166: 17165:Roxithromycin 17163: 17161: 17158: 17156: 17153: 17151: 17148: 17146: 17143: 17141: 17138: 17136: 17133: 17131: 17128: 17126: 17123: 17121: 17118: 17116: 17113: 17111: 17108: 17106: 17103: 17101: 17098: 17096: 17093: 17091: 17088: 17086: 17083: 17081: 17078: 17076: 17073: 17071: 17068: 17066: 17063: 17061: 17058: 17056: 17053: 17051: 17048: 17046: 17043: 17041: 17038: 17036: 17033: 17031: 17028: 17026: 17023: 17021: 17018: 17016: 17013: 17011: 17008: 17002: 16998: 16997: 16994: 16991: 16989: 16986: 16984: 16981: 16979: 16976: 16974: 16971: 16969: 16966: 16964: 16961: 16959: 16956: 16954: 16951: 16949: 16946: 16944: 16941: 16939: 16936: 16934: 16931: 16929: 16926: 16924: 16921: 16919: 16916: 16914: 16911: 16909: 16906: 16904: 16901: 16899: 16896: 16894: 16891: 16889: 16886: 16884: 16881: 16879: 16876: 16874: 16871: 16869: 16866: 16864: 16861: 16859: 16858:Charybdotoxin 16856: 16854: 16851: 16849: 16846: 16844: 16841: 16839: 16836: 16834: 16831: 16829: 16826: 16824: 16821: 16819: 16816: 16815: 16813: 16811: 16807: 16804: 16799: 16793: 16790: 16788: 16784: 16770: 16767: 16765: 16761: 16760: 16758: 16756: 16752: 16746: 16743: 16741: 16740:Trimethadione 16738: 16736: 16733: 16731: 16728: 16726: 16723: 16721: 16718: 16716: 16713: 16711: 16708: 16706: 16703: 16701: 16698: 16696: 16693: 16691: 16688: 16686: 16683: 16681: 16678: 16676: 16673: 16671: 16668: 16666: 16663: 16661: 16658: 16656: 16653: 16651: 16648: 16646: 16643: 16641: 16638: 16636: 16633: 16631: 16628: 16626: 16623: 16621: 16618: 16616: 16613: 16611: 16608: 16606: 16603: 16601: 16598: 16596: 16593: 16591: 16588: 16586: 16583: 16581: 16580:Diproteverine 16578: 16576: 16573: 16571: 16568: 16566: 16563: 16561: 16558: 16556: 16553: 16551: 16548: 16546: 16543: 16541: 16538: 16535: 16534: 16531: 16528: 16526: 16523: 16521: 16518: 16516: 16513: 16511: 16508: 16506: 16503: 16501: 16498: 16496: 16493: 16491: 16488: 16486: 16483: 16481: 16478: 16476: 16473: 16471: 16468: 16466: 16463: 16461: 16457: 16449: 16448: 16445: 16442: 16440: 16439:Ruthenium red 16437: 16435: 16432: 16430: 16427: 16425: 16422: 16420: 16417: 16415: 16414:Levetiracetam 16412: 16410: 16407: 16405: 16402: 16400: 16397: 16395: 16392: 16390: 16387: 16385: 16382: 16380: 16377: 16375: 16372: 16370: 16367: 16365: 16364:ω-Agatoxin TK 16362: 16359: 16358: 16355: 16352: 16350: 16347: 16345: 16342: 16340: 16337: 16335: 16334:Niflumic acid 16332: 16330: 16327: 16325: 16322: 16320: 16316: 16315: 16312: 16309: 16307: 16303: 16302: 16299: 16296: 16294: 16291: 16289: 16285: 16284: 16281: 16278: 16276: 16273: 16271: 16268: 16266: 16263: 16261: 16258: 16256: 16253: 16251: 16248: 16246: 16243: 16241: 16238: 16236: 16233: 16231: 16227: 16226: 16223: 16220: 16218: 16215: 16213: 16210: 16208: 16205: 16203: 16200: 16198: 16195: 16193: 16190: 16188: 16185: 16183: 16180: 16176: 16173: 16171: 16168: 16166: 16163: 16161: 16158: 16156: 16153: 16151: 16148: 16146: 16143: 16141: 16138: 16136: 16133: 16131: 16128: 16126: 16123: 16121: 16118: 16116: 16113: 16111: 16108: 16106: 16101: 16098: 16096: 16093: 16091: 16088: 16086: 16083: 16081: 16078: 16076: 16071: 16068: 16066: 16063: 16061: 16058: 16056: 16053: 16051: 16048: 16046: 16043: 16041: 16038: 16036: 16033: 16031: 16028: 16026: 16023: 16021: 16018: 16016: 16013: 16011: 16008: 16006: 16003: 16001: 15998: 15996: 15993: 15991: 15988: 15986: 15983: 15981: 15978: 15976: 15973: 15971: 15968: 15966: 15963: 15961: 15958: 15956: 15955:Levamlodipine 15953: 15951: 15950:Lercanidipine 15948: 15946: 15943: 15941: 15938: 15936: 15933: 15931: 15928: 15926: 15923: 15921: 15918: 15916: 15913: 15911: 15908: 15906: 15903: 15901: 15898: 15896: 15893: 15891: 15888: 15886: 15883: 15881: 15878: 15876: 15873: 15871: 15868: 15866: 15863: 15861: 15857: 15855: 15851: 15850: 15848: 15846: 15842: 15839: 15834: 15828: 15825: 15823: 15819: 15815: 15808: 15803: 15801: 15796: 15794: 15789: 15788: 15785: 15772: 15771: 15766: 15763: 15762: 15757: 15754: 15753: 15748: 15745: 15744: 15739: 15736: 15735: 15734:Serotonergics 15730: 15727: 15726: 15721: 15718: 15717: 15714: 15709: 15708: 15705: 15695: 15692: 15690: 15687: 15685: 15682: 15680: 15677: 15675: 15672: 15670: 15667: 15665: 15662: 15660: 15657: 15655: 15654:Sonepiprazole 15652: 15650: 15647: 15645: 15642: 15640: 15637: 15635: 15632: 15630: 15627: 15625: 15622: 15620: 15617: 15615: 15612: 15610: 15607: 15605: 15602: 15600: 15597: 15595: 15592: 15590: 15587: 15585: 15582: 15580: 15577: 15575: 15572: 15570: 15569:Iodobenzamide 15567: 15565: 15562: 15560: 15557: 15555: 15552: 15550: 15547: 15545: 15542: 15540: 15537: 15535: 15532: 15530: 15529:Bromocriptine 15527: 15525: 15522: 15520: 15517: 15515: 15512: 15510: 15506: 15503: 15502: 15499: 15496: 15494: 15491: 15489: 15486: 15484: 15481: 15479: 15475: 15472: 15471: 15468: 15465: 15463: 15460: 15458: 15455: 15453: 15450: 15448: 15445: 15443: 15440: 15438: 15435: 15433: 15430: 15428: 15425: 15423: 15420: 15418: 15415: 15413: 15410: 15408: 15405: 15403: 15402:Benzquinamide 15400: 15398: 15395: 15393: 15390: 15388: 15385: 15383: 15379: 15376: 15375: 15372: 15369: 15367: 15364: 15362: 15359: 15357: 15354: 15352: 15349: 15347: 15344: 15342: 15339: 15337: 15334: 15332: 15329: 15327: 15324: 15322: 15319: 15317: 15314: 15312: 15309: 15307: 15304: 15302: 15299: 15297: 15294: 15291: 15287: 15284: 15282: 15279: 15277: 15274: 15272: 15269: 15267: 15264: 15262: 15259: 15257: 15254: 15252: 15249: 15247: 15244: 15242: 15239: 15237: 15234: 15232: 15229: 15227: 15224: 15222: 15221:DHA-clozapine 15219: 15217: 15214: 15212: 15209: 15207: 15204: 15202: 15199: 15197: 15194: 15192: 15189: 15187: 15184: 15182: 15179: 15177: 15174: 15172: 15169: 15167: 15163: 15160: 15159: 15156: 15153: 15151: 15148: 15146: 15145:Trifluperidol 15143: 15141: 15138: 15135: 15131: 15128: 15126: 15123: 15121: 15118: 15116: 15113: 15111: 15108: 15106: 15105:Thiopropazate 15103: 15101: 15098: 15096: 15093: 15091: 15088: 15086: 15085:Sulforidazine 15083: 15081: 15078: 15076: 15073: 15071: 15068: 15066: 15063: 15061: 15058: 15056: 15053: 15051: 15048: 15046: 15043: 15040: 15036: 15033: 15031: 15028: 15026: 15023: 15021: 15018: 15016: 15013: 15011: 15008: 15006: 15003: 15001: 14998: 14996: 14993: 14991: 14988: 14986: 14985:Levosulpiride 14983: 14981: 14978: 14976: 14973: 14971: 14968: 14966: 14963: 14961: 14958: 14956: 14955:Fluprothixene 14953: 14951: 14948: 14945: 14941: 14938: 14936: 14933: 14931: 14928: 14926: 14923: 14921: 14918: 14916: 14913: 14911: 14908: 14906: 14903: 14901: 14898: 14896: 14893: 14891: 14888: 14886: 14883: 14881: 14878: 14876: 14873: 14871: 14868: 14866: 14863: 14861: 14858: 14856: 14853: 14851: 14848: 14846: 14843: 14841: 14837: 14834: 14833: 14831: 14827: 14821: 14818: 14816: 14813: 14811: 14808: 14806: 14803: 14801: 14798: 14796: 14793: 14791: 14788: 14786: 14783: 14781: 14778: 14776: 14773: 14771: 14768: 14766: 14763: 14761: 14758: 14756: 14753: 14751: 14748: 14746: 14743: 14741: 14738: 14736: 14733: 14731: 14730:Phencyclidine 14728: 14726: 14723: 14721: 14718: 14716: 14713: 14711: 14708: 14706: 14703: 14701: 14698: 14696: 14693: 14691: 14688: 14686: 14683: 14681: 14678: 14676: 14673: 14671: 14668: 14666: 14663: 14661: 14658: 14656: 14653: 14651: 14648: 14646: 14643: 14641: 14638: 14636: 14633: 14631: 14628: 14626: 14623: 14621: 14618: 14616: 14613: 14611: 14607: 14604: 14603: 14600: 14597: 14595: 14592: 14590: 14587: 14585: 14582: 14580: 14579:Brilaroxazine 14577: 14575: 14574:Brexpiprazole 14572: 14570: 14567: 14565: 14562: 14559: 14555: 14552: 14550: 14546: 14543: 14542: 14539: 14536: 14534: 14531: 14529: 14523: 14521: 14515: 14513: 14507: 14505: 14502: 14500: 14497: 14495: 14492: 14490: 14486: 14483: 14482: 14479: 14476: 14474: 14471: 14469: 14468:Dihydrexidine 14466: 14464: 14461: 14459: 14455: 14452: 14451: 14448: 14445: 14443: 14440: 14438: 14435: 14433: 14430: 14428: 14425: 14423: 14420: 14418: 14415: 14413: 14410: 14408: 14405: 14403: 14400: 14398: 14397:Bromocriptine 14394: 14391: 14390: 14387: 14384: 14382: 14379: 14377: 14374: 14372: 14369: 14367: 14363: 14360: 14359: 14356: 14353: 14351: 14348: 14346: 14342: 14339: 14338: 14336: 14332: 14329: 14327: 14319: 14309: 14306: 14304: 14301: 14299: 14296: 14294: 14291: 14289: 14286: 14284: 14281: 14279: 14275: 14272: 14271: 14268: 14265: 14263: 14260: 14258: 14255: 14253: 14250: 14248: 14245: 14243: 14240: 14238: 14235: 14232: 14228: 14225: 14223: 14222:Norquetiapine 14220: 14218: 14215: 14213: 14210: 14208: 14205: 14203: 14202:DHA-clozapine 14200: 14198: 14195: 14193: 14190: 14188: 14185: 14183: 14179: 14176: 14175: 14172: 14169: 14166: 14162: 14159: 14157: 14154: 14152: 14149: 14147: 14144: 14141: 14137: 14134: 14132: 14129: 14127: 14124: 14121: 14117: 14114: 14112: 14109: 14107: 14104: 14102: 14098: 14095: 14094: 14092: 14088: 14082: 14079: 14077: 14074: 14072: 14068: 14065: 14064: 14062: 14058: 14052: 14049: 14047: 14044: 14042: 14039: 14037: 14034: 14032: 14029: 14027: 14024: 14022: 14019: 14017: 14014: 14012: 14009: 14007: 14004: 14002: 13999: 13997: 13994: 13992: 13988: 13985: 13984: 13981: 13978: 13976: 13970: 13968: 13962: 13960: 13957: 13955: 13949: 13947: 13944: 13942: 13939: 13937: 13934: 13932: 13929: 13927: 13923: 13920: 13919: 13916: 13913: 13911: 13908: 13906: 13903: 13901: 13900:Dihydrexidine 13898: 13896: 13893: 13891: 13888: 13886: 13882: 13879: 13878: 13875: 13872: 13870: 13867: 13865: 13862: 13860: 13857: 13855: 13852: 13850: 13847: 13845: 13841: 13838: 13837: 13834: 13831: 13829: 13826: 13824: 13821: 13819: 13816: 13814: 13811: 13809: 13806: 13804: 13801: 13799: 13796: 13794: 13790: 13787: 13786: 13784: 13780: 13777: 13775: 13767: 13763: 13760: 13753: 13748: 13746: 13741: 13739: 13734: 13733: 13730: 13712: 13709: 13707: 13704: 13702: 13699: 13696: 13695: 13692: 13686: 13683: 13681: 13678: 13676: 13673: 13671: 13668: 13666: 13663: 13661: 13658: 13656: 13653: 13651: 13648: 13646: 13643: 13640: 13636: 13633: 13631: 13628: 13626: 13623: 13622: 13620: 13616: 13610: 13606: 13596: 13593: 13591: 13588: 13586: 13583: 13581: 13578: 13576: 13573: 13571: 13568: 13566: 13563: 13561: 13558: 13556: 13553: 13551: 13548: 13546: 13543: 13541: 13538: 13536: 13533: 13531: 13528: 13526: 13523: 13521: 13518: 13516: 13513: 13511: 13508: 13506: 13503: 13501: 13498: 13496: 13495:Phencyclidine 13493: 13491: 13488: 13486: 13483: 13481: 13478: 13476: 13473: 13471: 13468: 13466: 13465:Nitrous oxide 13463: 13461: 13458: 13456: 13453: 13451: 13448: 13446: 13443: 13441: 13438: 13436: 13433: 13431: 13428: 13426: 13423: 13421: 13418: 13416: 13413: 13411: 13408: 13406: 13405:Levomethadone 13403: 13401: 13398: 13396: 13393: 13391: 13388: 13386: 13383: 13381: 13378: 13376: 13373: 13371: 13368: 13366: 13363: 13361: 13358: 13356: 13353: 13351: 13350:Hexafluronium 13348: 13346: 13343: 13341: 13338: 13336: 13333: 13331: 13328: 13326: 13323: 13321: 13318: 13316: 13313: 13311: 13308: 13306: 13303: 13301: 13298: 13296: 13293: 13291: 13288: 13286: 13283: 13281: 13278: 13276: 13273: 13271: 13268: 13266: 13263: 13261: 13258: 13256: 13253: 13251: 13248: 13246: 13243: 13241: 13240:Decamethonium 13238: 13236: 13233: 13231: 13228: 13226: 13223: 13221: 13218: 13216: 13213: 13211: 13210:Cisatracurium 13208: 13206: 13203: 13201: 13198: 13196: 13193: 13191: 13188: 13186: 13183: 13180: 13176: 13172: 13171:Bungarotoxins 13169: 13167: 13164: 13161: 13157: 13156:pentobarbital 13153: 13150: 13148: 13145: 13143: 13140: 13138: 13135: 13133: 13130: 13128: 13125: 13123: 13120: 13118: 13115: 13112: 13108: 13104: 13100: 13099:α-Neurotoxins 13097: 13095: 13092: 13090: 13087: 13086: 13084: 13078: 13071: 13067: 13061: 13058: 13056: 13053: 13051: 13048: 13046: 13043: 13041: 13038: 13036: 13033: 13031: 13028: 13026: 13023: 13021: 13018: 13016: 13013: 13011: 13008: 13006: 13003: 13001: 12998: 12996: 12993: 12991: 12988: 12986: 12983: 12981: 12978: 12976: 12973: 12971: 12968: 12966: 12963: 12961: 12958: 12956: 12953: 12951: 12948: 12946: 12943: 12941: 12938: 12936: 12933: 12931: 12928: 12926: 12923: 12921: 12918: 12916: 12913: 12911: 12908: 12906: 12903: 12900: 12896: 12893: 12891: 12888: 12886: 12883: 12881: 12878: 12876: 12873: 12871: 12868: 12866: 12863: 12861: 12858: 12856: 12853: 12851: 12848: 12846: 12843: 12841: 12838: 12836: 12833: 12831: 12828: 12826: 12823: 12821: 12818: 12816: 12813: 12811: 12808: 12806: 12803: 12801: 12800:Decamethonium 12798: 12796: 12793: 12791: 12788: 12786: 12783: 12781: 12778: 12776: 12773: 12771: 12768: 12766: 12763: 12761: 12758: 12756: 12753: 12751: 12748: 12746: 12743: 12741: 12738: 12736: 12735:Acetylcholine 12733: 12731: 12728: 12726: 12723: 12721: 12718: 12716: 12713: 12711: 12708: 12706: 12703: 12701: 12698: 12696: 12693: 12691: 12688: 12686: 12683: 12682: 12680: 12674: 12667: 12663: 12660: 12655: 12649: 12645: 12642: 12635: 12630: 12628: 12623: 12621: 12616: 12615: 12612: 12600: 12597: 12595: 12592: 12590: 12587: 12584: 12583: 12580: 12574: 12571: 12569: 12566: 12564: 12561: 12559: 12556: 12554: 12551: 12549: 12546: 12544: 12541: 12539: 12536: 12534: 12531: 12528: 12524: 12521: 12519: 12516: 12514: 12511: 12510: 12508: 12504: 12498: 12494: 12484: 12481: 12479: 12476: 12474: 12471: 12468: 12464: 12461: 12458: 12454: 12450: 12446: 12442: 12438: 12434: 12431: 12429: 12426: 12424: 12421: 12419: 12416: 12414: 12411: 12409: 12406: 12404: 12401: 12399: 12396: 12394: 12393:Tridihexethyl 12391: 12388: 12384: 12380: 12379:protriptyline 12376: 12375:nortriptyline 12372: 12368: 12367:nitroxazepine 12364: 12360: 12356: 12352: 12348: 12344: 12340: 12336: 12332: 12328: 12324: 12320: 12319:+perphenazine 12316: 12315:amitriptyline 12312: 12309: 12307: 12304: 12302: 12299: 12297: 12294: 12292: 12289: 12287: 12284: 12282: 12279: 12276: 12272: 12268: 12264: 12260: 12257: 12255: 12252: 12250: 12247: 12244: 12240: 12233: 12228: 12226: 12223: 12221: 12218: 12216: 12213: 12211: 12208: 12206: 12203: 12201: 12198: 12196: 12193: 12191: 12188: 12186: 12183: 12181: 12178: 12176: 12173: 12171: 12168: 12166: 12163: 12161: 12158: 12156: 12153: 12151: 12148: 12146: 12143: 12141: 12138: 12136: 12133: 12131: 12128: 12126: 12123: 12121: 12118: 12116: 12113: 12111: 12108: 12106: 12103: 12101: 12098: 12096: 12093: 12091: 12088: 12086: 12083: 12081: 12078: 12076: 12073: 12071: 12068: 12066: 12063: 12061: 12058: 12056: 12053: 12051: 12048: 12046: 12043: 12041: 12038: 12036: 12033: 12031: 12028: 12026: 12023: 12021: 12018: 12016: 12013: 12011: 12008: 12006: 12003: 12001: 11998: 11996: 11993: 11991: 11988: 11986: 11983: 11981: 11978: 11976: 11975:Methoctramine 11973: 11971: 11970:Methantheline 11968: 11966: 11963: 11961: 11958: 11956: 11953: 11951: 11948: 11946: 11945:Mamba toxin 7 11943: 11941: 11940:Mamba toxin 3 11938: 11936: 11933: 11931: 11928: 11926: 11923: 11920: 11916: 11913: 11911: 11908: 11906: 11903: 11901: 11898: 11896: 11893: 11891: 11888: 11886: 11883: 11881: 11878: 11876: 11873: 11870: 11866: 11862: 11858: 11855: 11853: 11850: 11848: 11845: 11843: 11840: 11838: 11837:Fenpiverinium 11835: 11833: 11830: 11828: 11825: 11823: 11820: 11818: 11815: 11813: 11810: 11808: 11805: 11803: 11800: 11798: 11795: 11793: 11790: 11788: 11785: 11783: 11780: 11778: 11775: 11773: 11770: 11768: 11765: 11763: 11760: 11758: 11755: 11753: 11750: 11748: 11745: 11743: 11740: 11738: 11735: 11733: 11730: 11728: 11725: 11723: 11720: 11718: 11715: 11713: 11710: 11708: 11705: 11703: 11700: 11698: 11695: 11693: 11690: 11688: 11685: 11683: 11680: 11678: 11675: 11673: 11670: 11668: 11665: 11663: 11660: 11658: 11655: 11653: 11650: 11648: 11645: 11643: 11640: 11638: 11635: 11633: 11630: 11628: 11625: 11622: 11618: 11614: 11610: 11606: 11602: 11598: 11594: 11590: 11587: 11585: 11582: 11580: 11577: 11575: 11572: 11569: 11565: 11561: 11557: 11553: 11549: 11545: 11541: 11537: 11533: 11529: 11525: 11521: 11517: 11513: 11509: 11505: 11501: 11497: 11493: 11489: 11486: 11484: 11481: 11479: 11476: 11474: 11471: 11469: 11466: 11464: 11461: 11459: 11456: 11453: 11449: 11446: 11444: 11441: 11439: 11436: 11435: 11433: 11431: 11427: 11421: 11418: 11416: 11413: 11411: 11408: 11406: 11403: 11401: 11398: 11396: 11393: 11391: 11388: 11386: 11383: 11381: 11378: 11376: 11373: 11371: 11368: 11366: 11363: 11361: 11358: 11356: 11353: 11351: 11348: 11346: 11343: 11341: 11338: 11336: 11333: 11331: 11328: 11326: 11323: 11321: 11318: 11316: 11313: 11311: 11308: 11306: 11303: 11301: 11298: 11296: 11293: 11291: 11288: 11286: 11283: 11281: 11278: 11276: 11273: 11271: 11268: 11266: 11263: 11261: 11258: 11256: 11255:cis-Dioxolane 11253: 11251: 11248: 11246: 11243: 11241: 11238: 11236: 11233: 11231: 11228: 11226: 11223: 11221: 11218: 11216: 11213: 11211: 11208: 11206: 11203: 11201: 11198: 11196: 11193: 11191: 11188: 11186: 11183: 11181: 11178: 11176: 11173: 11171: 11170:Acetylcholine 11168: 11166: 11163: 11161: 11158: 11156: 11153: 11151: 11148: 11147: 11145: 11143: 11139: 11136: 11131: 11125: 11121: 11118: 11111: 11106: 11104: 11099: 11097: 11092: 11091: 11088: 11082: 11078: 11075: 11070: 11064: 11060: 11055: 11048: 11045: 11044: 11031: 11027: 11023: 11019: 11015: 11011: 11007: 11000: 10992: 10988: 10984: 10980: 10973: 10958: 10954: 10953: 10946: 10930: 10926: 10920: 10916: 10915: 10907: 10899: 10895: 10892:(9): 1181–6. 10891: 10887: 10880: 10872: 10868: 10864: 10860: 10856: 10852: 10845: 10837: 10833: 10829: 10825: 10820: 10815: 10811: 10807: 10804:(5): 321–33. 10803: 10799: 10795: 10788: 10780: 10776: 10771: 10766: 10761: 10756: 10752: 10748: 10744: 10737: 10729: 10725: 10720: 10715: 10711: 10707: 10703: 10699: 10695: 10691: 10687: 10680: 10672: 10668: 10663: 10658: 10654: 10650: 10646: 10639: 10623: 10619: 10615: 10609: 10593: 10589: 10585: 10578: 10562: 10558: 10554: 10550: 10544: 10528: 10524: 10520: 10513: 10496: 10492: 10477: 10473: 10469: 10463: 10446: 10442: 10437: 10431: 10429: 10412: 10408: 10404: 10400: 10396: 10389: 10381: 10375: 10371: 10364: 10354: 10348: 10344: 10340: 10336: 10332: 10326: 10322: 10318: 10314: 10310: 10305: 10301: 10295: 10291: 10287: 10282: 10278: 10272: 10268: 10264: 10260: 10256: 10252: 10247: 10243: 10237: 10233: 10229: 10225: 10224: 10219: 10215: 10214: 10210: 10202: 10196: 10192: 10187: 10186: 10177: 10169: 10165: 10161: 10157: 10154:(6): 389–91. 10153: 10149: 10142: 10131: 10127: 10123: 10122: 10114: 10110: 10104: 10088: 10084: 10083: 10078: 10071: 10052: 10048: 10044: 10040: 10033: 10032: 10027: 10021: 10013: 10009: 10008: 10003: 9996: 9980: 9976: 9975: 9970: 9964: 9946: 9942: 9938: 9923: 9919: 9918: 9915: 9907: 9903: 9899: 9895: 9891: 9887: 9883: 9882: 9878: 9862: 9858: 9851: 9843: 9837: 9833: 9832: 9825: 9817: 9813: 9809: 9805: 9801: 9797: 9793: 9789: 9782: 9766: 9762: 9758: 9751: 9743: 9739: 9735: 9731: 9727: 9723: 9719: 9715: 9708: 9692: 9688: 9684: 9678: 9676: 9667: 9663: 9658: 9653: 9648: 9643: 9639: 9635: 9631: 9624: 9616: 9612: 9608: 9604: 9600: 9596: 9592: 9588: 9581: 9574: 9568: 9558: 9548: 9540: 9536: 9532: 9528: 9520: 9512: 9508: 9504: 9501:(in German). 9500: 9493: 9478: 9474: 9465: 9461: 9457: 9453: 9449: 9445: 9441: 9440: 9434: 9433: 9429: 9421: 9417: 9412: 9407: 9403: 9399: 9396:(2): 276–84. 9395: 9391: 9387: 9380: 9372: 9368: 9362: 9358: 9357: 9349: 9341: 9337: 9332: 9327: 9323: 9319: 9315: 9308: 9300: 9296: 9291: 9286: 9282: 9278: 9274: 9267: 9259: 9255: 9251: 9247: 9242: 9237: 9233: 9229: 9225: 9218: 9210: 9206: 9201: 9196: 9192: 9188: 9184: 9177: 9175: 9166: 9162: 9158: 9154: 9150: 9146: 9142: 9138: 9131: 9129: 9120: 9116: 9111: 9106: 9102: 9098: 9094: 9087: 9079: 9075: 9071: 9067: 9063: 9059: 9051: 9043: 9037: 9033: 9032: 9025: 9017: 9013: 9009: 9005: 9001: 8997: 8993: 8989: 8982: 8974: 8970: 8966: 8962: 8958: 8954: 8950: 8946: 8939: 8931: 8927: 8923: 8919: 8915: 8911: 8907: 8903: 8895: 8893: 8884: 8880: 8876: 8872: 8868: 8864: 8860: 8856: 8849: 8847: 8838: 8834: 8829: 8824: 8820: 8816: 8812: 8808: 8804: 8797: 8789: 8785: 8781: 8777: 8772: 8767: 8764:(4): 903–17. 8763: 8759: 8755: 8748: 8740: 8736: 8731: 8726: 8722: 8718: 8714: 8707: 8699: 8695: 8691: 8687: 8683: 8679: 8672: 8670: 8668: 8666: 8657: 8653: 8649: 8645: 8641: 8637: 8633: 8629: 8622: 8614: 8610: 8605: 8600: 8596: 8592: 8588: 8584: 8580: 8573: 8565: 8561: 8556: 8551: 8547: 8543: 8539: 8535: 8531: 8524: 8516: 8512: 8508: 8504: 8499: 8494: 8491:(3): 768–74. 8490: 8486: 8482: 8475: 8473: 8464: 8460: 8455: 8450: 8446: 8442: 8438: 8434: 8430: 8423: 8415: 8411: 8407: 8403: 8398: 8393: 8389: 8385: 8381: 8374: 8372: 8370: 8368: 8366: 8364: 8355: 8351: 8347: 8343: 8338: 8333: 8329: 8325: 8321: 8314: 8306: 8302: 8298: 8294: 8291:(1–3): 53–6. 8290: 8286: 8278: 8276: 8267: 8263: 8258: 8253: 8249: 8245: 8242:(1): 159–70. 8241: 8237: 8233: 8226: 8224: 8222: 8220: 8218: 8209: 8205: 8200: 8195: 8192:(8): 837–44. 8191: 8187: 8183: 8176: 8174: 8165: 8161: 8157: 8153: 8149: 8145: 8142:(4): 308–17. 8141: 8137: 8130: 8122: 8118: 8113: 8108: 8104: 8100: 8097:(2): 263–74. 8096: 8092: 8088: 8081: 8073: 8069: 8065: 8061: 8057: 8053: 8049: 8045: 8038: 8030: 8026: 8021: 8016: 8013:(1): 174–82. 8012: 8008: 8004: 7997: 7995: 7986: 7982: 7977: 7972: 7967: 7962: 7958: 7954: 7951:(3): e59334. 7950: 7946: 7942: 7938: 7932: 7930: 7928: 7926: 7917: 7913: 7908: 7903: 7899: 7895: 7891: 7887: 7883: 7876: 7868: 7864: 7860: 7856: 7851: 7846: 7842: 7838: 7834: 7830: 7823: 7815: 7811: 7806: 7801: 7797: 7793: 7789: 7785: 7781: 7777: 7774:Björkholm C, 7770: 7762: 7758: 7753: 7748: 7744: 7740: 7736: 7732: 7728: 7721: 7713: 7709: 7704: 7699: 7695: 7691: 7687: 7683: 7679: 7672: 7664: 7660: 7656: 7652: 7648: 7644: 7640: 7636: 7632: 7628: 7621: 7613: 7609: 7604: 7599: 7595: 7591: 7587: 7580: 7572: 7568: 7563: 7558: 7554: 7550: 7546: 7542: 7538: 7531: 7529: 7527: 7525: 7523: 7506: 7502: 7496: 7488: 7484: 7479: 7474: 7470: 7466: 7462: 7458: 7454: 7447: 7445: 7436: 7432: 7427: 7422: 7418: 7414: 7410: 7406: 7402: 7395: 7393: 7384: 7380: 7376: 7372: 7368: 7364: 7360: 7356: 7349: 7347: 7338: 7334: 7329: 7324: 7320: 7316: 7312: 7305: 7303: 7294: 7290: 7286: 7282: 7278: 7274: 7273:J Clin Anesth 7266: 7258: 7254: 7249: 7244: 7240: 7236: 7232: 7225: 7217: 7213: 7209: 7205: 7200: 7195: 7191: 7187: 7183: 7176: 7168: 7164: 7160: 7156: 7151: 7146: 7142: 7138: 7134: 7127: 7119: 7115: 7111: 7107: 7104:(1): 121–33. 7103: 7099: 7092: 7084: 7080: 7075: 7070: 7066: 7062: 7058: 7054: 7050: 7043: 7035: 7031: 7026: 7021: 7016: 7011: 7007: 7003: 6999: 6992: 6984: 6980: 6975: 6970: 6966: 6962: 6958: 6954: 6950: 6943: 6927: 6923: 6919: 6915: 6911: 6906: 6901: 6897: 6893: 6889: 6882: 6874: 6870: 6866: 6862: 6858: 6854: 6850: 6846: 6839: 6837: 6835: 6833: 6824: 6820: 6815: 6810: 6807:(6): E343–6. 6806: 6802: 6798: 6791: 6783: 6779: 6774: 6769: 6765: 6761: 6757: 6753: 6749: 6742: 6734: 6730: 6726: 6722: 6718: 6714: 6710: 6706: 6699: 6697: 6695: 6693: 6691: 6682: 6678: 6674: 6670: 6666: 6662: 6657: 6652: 6648: 6644: 6637: 6629: 6625: 6620: 6615: 6611: 6607: 6603: 6599: 6595: 6588: 6586: 6584: 6575: 6571: 6567: 6563: 6559: 6555: 6551: 6547: 6540: 6524: 6520: 6516: 6511: 6506: 6502: 6498: 6494: 6487: 6479: 6475: 6470: 6465: 6460: 6455: 6451: 6447: 6443: 6436: 6428: 6424: 6420: 6416: 6411: 6406: 6402: 6398: 6394: 6390: 6382: 6374: 6370: 6366: 6362: 6358: 6354: 6350: 6346: 6339: 6331: 6325: 6321: 6314: 6298: 6294: 6288: 6280: 6276: 6271: 6266: 6262: 6258: 6254: 6250: 6246: 6239: 6237: 6228: 6224: 6219: 6214: 6210: 6206: 6202: 6198: 6194: 6187: 6185: 6168: 6164: 6158: 6142: 6138: 6132: 6116: 6112: 6108: 6104: 6100: 6096: 6092: 6088: 6084: 6080: 6073: 6057: 6053: 6049: 6045: 6041: 6036: 6031: 6027: 6023: 6019: 6015: 6011: 6004: 6002: 5993: 5989: 5984: 5979: 5975: 5971: 5967: 5963: 5959: 5952: 5944: 5940: 5936: 5932: 5928: 5924: 5920: 5916: 5909: 5907: 5905: 5903: 5894: 5890: 5886: 5882: 5878: 5874: 5870: 5866: 5859: 5857: 5855: 5846: 5842: 5838: 5834: 5830: 5826: 5822: 5818: 5811: 5803: 5799: 5794: 5789: 5784: 5779: 5775: 5771: 5767: 5760: 5752: 5748: 5743: 5738: 5735:(2): 145–61. 5734: 5730: 5726: 5719: 5711: 5707: 5702: 5697: 5692: 5687: 5683: 5679: 5675: 5668: 5660: 5656: 5651: 5646: 5642: 5638: 5634: 5627: 5619: 5615: 5611: 5607: 5600: 5592: 5588: 5584: 5580: 5575: 5570: 5566: 5562: 5558: 5551: 5543: 5539: 5534: 5529: 5525: 5521: 5517: 5513: 5509: 5502: 5500: 5498: 5489: 5485: 5480: 5475: 5470: 5465: 5462:(3): 154–61. 5461: 5457: 5453: 5446: 5438: 5434: 5429: 5424: 5419: 5414: 5411:(7): e27065. 5410: 5406: 5402: 5395: 5387: 5383: 5378: 5373: 5370:(3): 339–48. 5369: 5365: 5361: 5354: 5346: 5342: 5338: 5334: 5330: 5326: 5322: 5318: 5311: 5303: 5299: 5294: 5289: 5285: 5281: 5277: 5270: 5254: 5250: 5246: 5239: 5231: 5227: 5223: 5219: 5215: 5211: 5207: 5203: 5196: 5188: 5184: 5179: 5174: 5169: 5164: 5161:(3): 283–90. 5160: 5156: 5152: 5145: 5143: 5141: 5132: 5128: 5124: 5120: 5116: 5112: 5105: 5097: 5093: 5089: 5085: 5081: 5077: 5073: 5069: 5062: 5060: 5058: 5056: 5047: 5043: 5038: 5033: 5030:(6): 936–47. 5029: 5025: 5021: 5014: 5012: 5010: 5001: 4997: 4992: 4987: 4983: 4979: 4975: 4968: 4966: 4964: 4955: 4951: 4947: 4943: 4939: 4935: 4932:(4): 423–41. 4931: 4927: 4920: 4912: 4908: 4904: 4900: 4896: 4892: 4888: 4885:(in German). 4884: 4877: 4869: 4865: 4861: 4858:(4): 175–80. 4857: 4853: 4849: 4842: 4826: 4822: 4818: 4814: 4813: 4805: 4803: 4786: 4782: 4781: 4776: 4770: 4761: 4756: 4752: 4748: 4742: 4734: 4730: 4725: 4720: 4717:(3): 678–84. 4716: 4712: 4708: 4701: 4699: 4697: 4695: 4686: 4682: 4677: 4672: 4668: 4664: 4660: 4656: 4652: 4645: 4643: 4641: 4639: 4637: 4635: 4626: 4622: 4618: 4614: 4610: 4606: 4602: 4598: 4591: 4575: 4571: 4567: 4563: 4559: 4552: 4544: 4540: 4535: 4530: 4526: 4522: 4518: 4514: 4510: 4503: 4501: 4492: 4488: 4483: 4478: 4474: 4470: 4466: 4462: 4458: 4451: 4449: 4447: 4445: 4436: 4432: 4428: 4424: 4420: 4416: 4412: 4408: 4400: 4398: 4396: 4394: 4385: 4381: 4377: 4373: 4369: 4365: 4361: 4357: 4350: 4348: 4346: 4337: 4333: 4329: 4325: 4320: 4315: 4311: 4307: 4303: 4296: 4288: 4284: 4280: 4276: 4272: 4268: 4264: 4260: 4253: 4251: 4242: 4238: 4233: 4228: 4224: 4220: 4216: 4209: 4207: 4205: 4196: 4192: 4187: 4182: 4178: 4174: 4170: 4166: 4165:Pharmacol Rev 4162: 4155: 4153: 4151: 4149: 4147: 4145: 4136: 4132: 4128: 4124: 4119: 4114: 4110: 4106: 4101: 4096: 4093:(1): 90–101. 4092: 4088: 4084: 4077: 4075: 4073: 4071: 4069: 4067: 4065: 4063: 4054: 4052:9780122608063 4048: 4044: 4040: 4036: 4029: 4021: 4017: 4013: 4009: 4005: 4001: 3997: 3993: 3986: 3984: 3982: 3980: 3971: 3967: 3963: 3959: 3955: 3951: 3947: 3943: 3936: 3928: 3924: 3920: 3916: 3912: 3908: 3905:(2): 157–77. 3904: 3900: 3893: 3891: 3889: 3872: 3868: 3864: 3859: 3854: 3850: 3846: 3842: 3835: 3833: 3831: 3829: 3827: 3825: 3823: 3821: 3812: 3808: 3804: 3798: 3794: 3790: 3786: 3779: 3777: 3775: 3773: 3771: 3769: 3767: 3765: 3756: 3752: 3748: 3744: 3740: 3736: 3733:(6): 825–31. 3732: 3728: 3721: 3719: 3710: 3706: 3701: 3696: 3692: 3688: 3684: 3680: 3676: 3669: 3667: 3665: 3663: 3661: 3659: 3657: 3655: 3646: 3642: 3637: 3632: 3628: 3624: 3620: 3616: 3612: 3605: 3603: 3601: 3599: 3597: 3595: 3593: 3591: 3589: 3580: 3576: 3570: 3566: 3565: 3557: 3555: 3538: 3534: 3530: 3523: 3515: 3511: 3505: 3501: 3500: 3492: 3490: 3488: 3486: 3484: 3482: 3480: 3478: 3476: 3474: 3472: 3470: 3468: 3466: 3464: 3455: 3451: 3447: 3443: 3436: 3417: 3413: 3409: 3404: 3399: 3395: 3391: 3387: 3383: 3376: 3369: 3362: 3358: 3354: 3348: 3331: 3327: 3321: 3305: 3301: 3297: 3291: 3283: 3279: 3273: 3269: 3268: 3260: 3256: 3248: 3245: 3243: 3239: 3235: 3231: 3227: 3223: 3219: 3215: 3211: 3201: 3199: 3195: 3191: 3186: 3184: 3180: 3170: 3168: 3164: 3160: 3159:Matthew Perry 3156: 3150: 3148: 3144: 3140: 3136: 3132: 3131:David Woodard 3128: 3124: 3120: 3119:John C. Lilly 3116: 3112: 3111:derealization 3108: 3104: 3098: 3085: 3081: 3078: 3074: 3070: 3067: 3063: 3059: 3055: 3052: 3048: 3045: 3041: 3037: 3036: 3035: 3033: 3022: 3012: 3011:development. 3008: 3006: 3002: 3001:phencyclidine 2998: 2994: 2990: 2986: 2982: 2972: 2963: 2961: 2957: 2953: 2952:hydrochloride 2949: 2945: 2941: 2937: 2933: 2929: 2924: 2922: 2918: 2914: 2910: 2906: 2902: 2898: 2887: 2881: 2872: 2866: 2848: 2844: 2842: 2838: 2834: 2830: 2826: 2822: 2818: 2804: 2802: 2798: 2793: 2790: 2786: 2782: 2778: 2774: 2770: 2767: 2763: 2759: 2755: 2746: 2742: 2740: 2736: 2731: 2728: 2724: 2720: 2710: 2708: 2703: 2702:nitrous oxide 2698: 2694: 2685: 2678: 2675: 2671: 2667: 2663: 2660: 2656: 2655:bromocriptine 2639: 2638:Philip Seeman 2630: 2628: 2624: 2620: 2616: 2612: 2608: 2604: 2600: 2596: 2592: 2585: 2581: 2573: 2568: 2565: 2563: 2558: 2557:counterpart. 2556: 2552: 2548: 2544: 2543:stereoisomers 2540: 2536: 2532: 2528: 2527:NMDA receptor 2517: 2514: 2511: 2508: 2502: 2499: 2497: 2494: 2493: 2490: 2487: 2484: 2478: 2475: 2470: 2465: 2464: 2461: 2458: 2455: 2449: 2446: 2441: 2436: 2435: 2432: 2429: 2426: 2420: 2417: 2412: 2407: 2406: 2403: 2400: 2395: 2389: 2386: 2381: 2376: 2375: 2372: 2369: 2366: 2360: 2357: 2355: 2349: 2348: 2345: 2342: 2339: 2333: 2330: 2328: 2318: 2317: 2314: 2311: 2308: 2302: 2299: 2297: 2287: 2286: 2283: 2280: 2277: 2271: 2268: 2266: 2256: 2255: 2252: 2249: 2246: 2240: 2237: 2235: 2225: 2224: 2221: 2218: 2215: 2209: 2206: 2201: 2189: 2188: 2185: 2182: 2179: 2173: 2170: 2165: 2153: 2152: 2149: 2146: 2141: 2135: 2132: 2130: 2124: 2123: 2119: 2116: 2109: 2098: 2093: 2091: 2085: 2084: 2081: 2078: 2073: 2067: 2064: 2062: 2056: 2055: 2051: 2048: 2043: 2032: 2027: 2022: 2017: 2016: 2013: 2010: 2007: 2001: 1998: 1993: 1985: 1984: 1981: 1978: 1975: 1969: 1966: 1961: 1956: 1955: 1952: 1949: 1946: 1940: 1937: 1932: 1927: 1926: 1922: 1919: 1916: 1913: 1910: 1906: 1903: 1902: 1887: 1885: 1881: 1877: 1873: 1869: 1865: 1861: 1857: 1853: 1852:limbic system 1849: 1846:to influence 1845: 1841: 1837: 1833: 1829: 1825: 1821: 1817: 1812: 1810: 1806: 1801: 1797: 1793: 1791: 1787: 1781: 1777: 1773: 1769: 1765: 1761: 1755: 1753: 1749: 1745: 1741: 1740:NMDA receptor 1737: 1733: 1729: 1725: 1705: 1702: 1700: 1696: 1692: 1688: 1684: 1680: 1676: 1666: 1663: 1659: 1655: 1651: 1640: 1638: 1634: 1630: 1626: 1622: 1621:biliary colic 1616: 1614: 1610: 1606: 1602: 1598: 1594: 1590: 1585: 1583: 1579: 1575: 1571: 1567: 1563: 1559: 1555: 1551: 1547: 1543: 1533: 1529: 1526: 1522: 1518: 1514: 1510: 1506: 1502: 1498: 1494: 1490: 1481: 1469: 1466: 1462: 1460: 1457: 1455: 1451: 1449: 1445: 1442: 1438: 1434: 1432: 1428: 1424: 1420: 1419: 1418: 1416: 1406: 1404: 1394: 1392: 1382: 1380: 1370: 1368: 1364: 1359: 1357: 1352: 1350: 1346: 1342: 1337: 1335: 1331: 1327: 1323: 1319: 1318: 1313: 1308: 1306: 1300: 1297: 1293: 1287: 1277: 1275: 1271: 1267: 1263: 1258: 1256: 1252: 1246: 1243: 1232: 1230: 1226: 1222: 1217: 1215: 1211: 1207: 1203: 1198: 1196: 1192: 1188: 1184: 1180: 1176: 1171: 1169: 1165: 1161: 1157: 1153: 1149: 1145: 1140: 1136: 1132: 1117: 1115: 1111: 1107: 1103: 1099: 1098:phencyclidine 1094: 1091: 1086: 1084: 1080: 1076: 1072: 1068: 1064: 1059: 1057: 1056:NMDA receptor 1053: 1049: 1045: 1041: 1037: 1027: 1020: 1011: 1006: 1005: 1002: 995: 986: 985: 982: 975: 971: 969: 968:Melting point 965: 959: 955: 952: 949: 945: 942: 941: 939: 936: 934: 930: 923: 919: 918: 916: 913: 908: 901: 899: 895: 871: 869: 865: 860: 856: 852: 849: 847: 845:ECHA InfoCard 841: 833: 829: 828:DTXSID8023187 825: 824: 822: 813: 809: 802: 798: 797: 795: 793: 789: 782: 778: 777: 775: 773: 769: 762: 757: 754: 750: 749: 747: 745: 741: 734: 730: 729: 727: 725: 721: 714: 710: 709: 707: 705: 701: 694: 690: 689: 687: 685: 681: 674: 670: 669: 667: 665: 661: 654: 650: 649: 647: 640: 636: 629: 624: 618: 614: 611: 607: 606: 603: 599: 598: 596: 594: 590: 582: 577: 576: 573: 566: 561: 555: 552: 549: 546: 545: 544: 542: 538: 532: 529: 526: 525: 524: 522: 518: 512: 509: 508: 507: 505: 498: 492: 489: 486: 483: 480: 479: 478: 476: 472: 467: 464: 462: 459: 457: 454: 453: 452: 450: 446: 441: 437: 433: 432: 430: 426: 423: 421: 417: 413: 411: 407: 401: 398: 395: 392: 389: 386: 383: 380: 377: 374: 371: 370:Intramuscular 368: 365: 362: 361: 360: 358: 354: 350: 346: 339: 330: 328: 318: 316: 306: 303: 294: 292: 283: 280: 270: 267: 257: 256: 254: 252: 248: 243: 235: 230: 227: 226: 224: 222: 218: 215: 211: 207: 203: 199: 196: 194: 190: 186: 184: 178: 175:Moderate–high 174: 172: 166: 160: 151: 150: 148: 146: 140: 133: 129: 119: 116: 111: 102: 101: 99: 97: 93: 89: 85: 83: 79: 75: 71: 67: 63: 61: 57: 54:Clinical data 52: 48: 43: 39: 34: 26: 22: 38815: 38814: 38776: 38672:barbiturates 38601:cannabinoids 38550:-containing 38360:Salvinorin A 38280:Levallorphan 38071: 37990:Salvinorin A 37883:WIN 55,212-2 37648:CUMYL-PINACA 37633:APP-FUBINACA 37618:AMB-FUBINACA 37613:ADSB-FUB-187 37598:ADB-FUBINACA 37593:ADB-CHMINACA 37498:5F-AB-PINACA 37150: 37089: 37043: 36802: 36772:Salvinorin A 36744:Cannabinoids 36722:Triprolidine 36697:Promethazine 36692:Procyclidine 36672:Orphenadrine 36502:Benzatropine 36191:Eticyclidine 36088: 35895:Aeruginascin 35806: 35769: 35730:Coronaridine 35676: 35629: 35625: 35606: 35602: 35593: 35589: 35573:5,6-diBr-DMT 35530: 35493: 35451: 35414: 35385:4,5-DHP-α-MT 35374: 35298:Fenfluramine 35131:Metaescaline 35111:Isobuscaline 34940: 34860: 34805: 34761: 34644:25I-NMe7DHBF 34634:25B-NMe7Indz 34624:25B-NMe7DHBF 34595: 34591: 34562:N-Ethyl-2C-B 34517:2CBFly-NBOMe 34472:25I-N2Nap1OH 34328: 34250: 34177: 34109: 34099:25TFM-NB4OMe 34031: 34021:25TFM-NB3OMe 33953: 33925: 33914: 33910: 33569: 33532:Methysergide 33337:2CBFly-NBOMe 33303:Psychedelics 33233:Lifetime use 33035:Liquor store 32953:South Africa 32583:War on drugs 32409:Soviet Union 32285:Legalization 32123:Drug tourism 31971:Wine tasting 31891:Beer culture 31853:Coffee break 31790:Cannabis tea 31725:Drug culture 31568:Cannabinoids 31497:Salvinorin A 31469: 31463:amyl nitrite 31320:Psychedelics 31072:/paracetamol 30985:Desomorphine 30825:Barbiturates 30676:Oxitriptan ( 30668: 30552:aripiprazole 30510: 30459:Metralindole 30450: 30420: 30410: 30389:Pivhydrazine 30379:Pheniprazine 30325: 30231:Trimipramine 30221:Quinupramine 30121:Clomipramine 30116:Butriptyline 30039:Teniloxazine 30034:Tandospirone 30019:Metryptamine 30014:Medifoxamine 30008: 29999:Indeloxazine 29953:Vortioxetine 29715:Escitalopram 29552: 29502:Orphenadrine 29477:Carisoprodol 29469:Myorelaxants 29419: 29269:Cannabinoids 29235:Floctafenine 29140:Salicylamide 28819:+paracetamol 28811:Dexibuprofen 28799:Flurbiprofen 28789:Benoxaprofen 28764:Propacetamol 28754:Parapropamol 28722:+hydrocodone 28663:+paracetamol 28632:Remifentanil 28622:Proheptazine 28552:Ketobemidone 28492:Alphaprodine 28439:+paracetamol 28427:Nicomorphine 28422:Nicodicodine 28378:+paracetamol 28350:+paracetamol 28333:Desomorphine 28262:+paracetamol 28110:Hydroxydione 28071: 28043:Remifentanil 27937:Methohexital 27932:Hexobarbital 27919:Barbiturates 27802:Cyclopropane 27789:Inhalational 27736:Medical uses 27710: 27709: 27664:Promethazine 27649:Perphenazine 27629:Fluphenazine 27604:Clocapramine 27579:Carvotroline 27555: 27545: 27481:Antagonists: 27480: 27440: 27316: 27267:Antagonists: 27266: 27216: 27168: 27040:Clomipramine 26976: 26961: 26954: 26933:Progesterone 26820:Antagonists: 26819: 26783:Pregnenolone 26704: 26670:Escitalopram 26590:Cloperastine 26565:Blarcamesine 26521: 26453: 26432:Prodynorphin 26424:Propeptides: 26423: 26322: 26293:Thienorphine 26116:JNJ-19385899 26101:Cebranopadol 26083:Ac-RYYRIK-NH 26075:Ac-RYYRWK-NH 25759:6β-Naltrexol 25676:Thienorphine 25641:Salvinorin A 25441:Levallorphan 25420: 25246:Cebranopadol 25105:Thienorphine 24915:6β-Naltrexol 24699:JNJ-20788560 24694:Isomethadone 24589:Deltorphin I 24584:Deltorphin A 24564:Cebranopadol 24559:Casokefamide 24393:Naltrexazone 24383:Naloxonazine 24308:Levallorphan 24155:6β-Naltrexol 24054:Thienorphine 24009:Remifentanil 23931: 23862:Nicomorphine 23857:Nicodicodine 23812:Morphiceptin 23712:Ketobemidone 23706: 23547:Desomorphine 23532:DAMGO (DAGO) 23512:Cebranopadol 23507:Casokefamide 23247: 23246: 23231: 23219: 23216: 23206: 23116:Bietaserpine 23088:Amphetamines 23011:Mifepristone 23001:Medifoxamine 22956: 22883: 22826:Clomipramine 22821:Cianopramine 22812: 22665:Diclofensine 22635:Brasofensine 22611: 22535: 22523:Vortioxetine 22474: 22393:Escitalopram 22349: 22271:Indeloxazine 22263: 22243: 22200: 22183:Oxaprotiline 22164: 22152:Trimipramine 22107:Clomipramine 22102:Cianopramine 22097:Butriptyline 22088: 21941:Diclofensine 21911:Brasofensine 21887: 21811: 21799:Solriamfetol 21725: 21708:Teniloxazine 21668:Esreboxetine 21639: 21571:Solriamfetol 21491:Medifoxamine 21455: 21381:Dimethocaine 21371:Diclofensine 21343: 21295: 21183:Difluoropine 21178:Dichloropane 21163:Brasofensine 21149: 21137:Pyrovalerone 21113: 21038:Piperidines: 21037: 20987:Piperazines: 20986: 20904: 20897: 20888: 20887: 20871: 20868: 20740: 20647:Cyclopropane 20628: 20611: 20589: 20525: 20477:Propoxyphene 20447:Orphenadrine 20352:Ketobemidone 20346: 20317:Eticyclidine 20252:Coronaridine 20237:ARL-15896-AR 20153: 20121: 20033:-Cycloserine 20015:Carisoprodol 19971: 19859: 19857:Antagonists: 19856: 19789: 19784: 19767: 19695:-Cycloserine 19636: 19575: 19572: 19516:Barbiturates 19512: 19489:Selurampanel 19444:Dasolampanel 19431:Antagonists: 19430: 19400: 19333: 19330: 19304: 19241:Cyclopropane 19227:Barbiturates 19223: 19195:Selurampanel 19145:Dasolampanel 19117:Antagonists: 19116: 19100:Pramiracetam 18976: 18924: 18921: 18849: 18848: 18759:Talniflumate 18297: 18286:Tetrodotoxin 18276:Neosaxitoxin 18267: 18212: 18186:Propoxycaine 18121:Dimethocaine 18054: 18050: 18019:Valnoctamide 17949:Fosphenytoin 17910: 17884:Procainamide 17874:Pilsicainide 17829:Disopyramide 17815: 17805: 17653: 17621: 17571: 17485: 17453:Ethosuximide 17438:Cloperastine 17416: 17385:Metahexamide 17380:Glycyclamide 17340:Glibornuride 17305: 17254: 17216: 17195:Thioridazine 17150:Promethazine 17135:Orphenadrine 17125:Ketoconazole 17110:Erythromycin 16999: 16762: 16690:Phensuximide 16670:Ochratoxin A 16610:Ethosuximide 16536: 16458:-selective ( 16450: 16360: 16317: 16304: 16286: 16235:ω-Conotoxins 16228: 16178: 16160:Norverapamil 16125:Dexverapamil 16103: 16077:derivatives: 16073: 16070:Vatanidipine 16065:Trombodipine 16030:Palonidipine 16015:Nitrendipine 15970:Mepirodipine 15875:Azelnidipine 15858: 15852: 15768: 15759: 15750: 15741: 15732: 15723: 15712: 15711: 15664:Stepholidine 15659:Spiroxatrine 15649:Seridopidine 15644:SB-277,011-A 15564:Fenfluramine 15524:Bromerguride 15504: 15498:Trimipramine 15493:Propiomazine 15473: 15452:Promethazine 15447:Metopimazine 15377: 15296:Paliperidone 15241:Fluperlapine 15231:Elopiprazole 15196:Clocapramine 15186:Carpipramine 15161: 15115:Thioridazine 15075:Prothipendyl 15035:Perphenazine 14995:Mesoridazine 14970:Homopipramol 14960:Fluspirilene 14950:Fluphenazine 14905:Clothixamide 14900:Clopenthixol 14875:Chloracizine 14870:Butaperazine 14840:Acepromazine 14835: 14795:Salvinorin A 14684: 14605: 14599:Norclozapine 14594:Lumateperone 14554:Aripiprazole 14544: 14484: 14453: 14407:Chanoclavine 14392: 14361: 14340: 14273: 14237:Paliperidone 14217:Norclozapine 14207:Fluperlapine 14177: 14151:Thioridazine 14136:Perphenazine 14126:Fluphenazine 14096: 14066: 14041:Stepholidine 13986: 13921: 13880: 13839: 13789:Benzazepines 13788: 13580:Tubocurarine 13510:Promegestone 13505:Progesterone 13420:Mecamylamine 13379: 13230:Cyclopropane 13220:Coronaridine 13152:Barbiturates 13137:Anatruxonium 13107:α-cobratoxin 12950:Sazetidine A 12870:JNJ-39393406 12860:Ispronicline 12457:thioridazine 12453:mesoridazine 12387:trimipramine 12383:quinupramine 12335:clomipramine 12327:butriptyline 12145:Procyclidine 12110:Piperidolate 12025:Orphenadrine 11925:Isopropamide 11910:Imidafenacin 11869:+neostigmine 11865:+indacaterol 11847:Fesoterodine 11777:Dihexyverine 11727:Cloperastine 11597:fluperlapine 11568:triprolidine 11564:propiomazine 11560:promethazine 11548:phenindamine 11365:Talsaclidine 11325:Oxotremorine 11300:Methacholine 11290:LY-2,033,298 11013: 11009: 11005: 10999: 10982: 10978: 10972: 10961:, retrieved 10957:the original 10951: 10945: 10933:. Retrieved 10913: 10906: 10889: 10885: 10879: 10854: 10850: 10844: 10801: 10797: 10787: 10750: 10746: 10736: 10693: 10689: 10679: 10655:(2): 65–67. 10652: 10648: 10638: 10626:. Retrieved 10617: 10608: 10596:. Retrieved 10587: 10577: 10565:. Retrieved 10561:the original 10552: 10543: 10531:. Retrieved 10522: 10512: 10499:. Retrieved 10480:. Retrieved 10471: 10462: 10449:. Retrieved 10435: 10415:. Retrieved 10398: 10388: 10369: 10363: 10342: 10312: 10289: 10250: 10222: 10209: 10184: 10176: 10151: 10147: 10141: 10125: 10119: 10103: 10091:. Retrieved 10080: 10070: 10058:, retrieved 10030: 10020: 10005: 9995: 9983:. Retrieved 9972: 9963: 9949:. Retrieved 9929:. Retrieved 9922:the original 9912: 9898:the original 9889: 9877: 9865:. Retrieved 9850: 9830: 9824: 9791: 9787: 9781: 9769:. Retrieved 9760: 9750: 9720:(4): 351–4. 9717: 9713: 9707: 9695:. Retrieved 9637: 9633: 9623: 9593:(1): 29–40. 9590: 9586: 9580: 9572: 9567: 9557: 9547: 9530: 9526: 9519: 9505:(3): 64–71. 9502: 9498: 9492: 9443: 9437: 9428: 9393: 9389: 9379: 9355: 9348: 9321: 9318:Br J Anaesth 9317: 9307: 9280: 9277:Br J Anaesth 9276: 9266: 9234:(2): 87–92. 9231: 9228:Anesth Analg 9227: 9217: 9190: 9187:Br J Anaesth 9186: 9143:(3): 253–8. 9140: 9136: 9103:(5): 590–3. 9100: 9096: 9086: 9061: 9057: 9050: 9030: 9024: 8991: 8987: 8981: 8948: 8944: 8938: 8905: 8901: 8858: 8854: 8810: 8806: 8796: 8761: 8757: 8747: 8723:(4): 441–4. 8720: 8716: 8706: 8681: 8677: 8631: 8627: 8621: 8589:(3): 600–9. 8586: 8582: 8572: 8537: 8533: 8523: 8488: 8484: 8436: 8432: 8422: 8387: 8383: 8327: 8324:Anesth Analg 8323: 8313: 8288: 8284: 8239: 8235: 8189: 8185: 8139: 8135: 8129: 8094: 8090: 8080: 8050:(2): 107–9. 8047: 8043: 8037: 8010: 8006: 7948: 7944: 7889: 7885: 7875: 7850:10138/311483 7832: 7828: 7822: 7787: 7783: 7776:Monteggia LM 7769: 7734: 7730: 7720: 7685: 7681: 7671: 7630: 7626: 7620: 7593: 7589: 7579: 7544: 7540: 7509:. Retrieved 7495: 7460: 7456: 7408: 7404: 7358: 7354: 7318: 7314: 7279:(1): 19–24. 7276: 7272: 7265: 7238: 7234: 7224: 7189: 7185: 7175: 7143:(3): 641–8. 7140: 7136: 7126: 7101: 7097: 7091: 7056: 7052: 7042: 7005: 7001: 6991: 6956: 6952: 6942: 6932:10 September 6930:. Retrieved 6898:(1): 27–30. 6895: 6891: 6881: 6848: 6844: 6804: 6800: 6790: 6755: 6751: 6741: 6712: 6708: 6646: 6642: 6636: 6601: 6597: 6549: 6545: 6539: 6527:. Retrieved 6500: 6496: 6486: 6449: 6446:Biomedicines 6445: 6435: 6392: 6388: 6381: 6348: 6344: 6338: 6319: 6313: 6301:. Retrieved 6287: 6252: 6248: 6200: 6196: 6171:. Retrieved 6157: 6145:. Retrieved 6131: 6119:. Retrieved 6089:(1): 29–45. 6086: 6082: 6072: 6062:10 September 6060:. Retrieved 6017: 6013: 5965: 5961: 5951: 5918: 5914: 5868: 5864: 5820: 5816: 5810: 5773: 5769: 5759: 5732: 5728: 5718: 5681: 5677: 5667: 5640: 5636: 5626: 5609: 5605: 5599: 5567:(3): 251–7. 5564: 5560: 5550: 5515: 5511: 5459: 5455: 5445: 5408: 5404: 5394: 5367: 5363: 5353: 5323:(8): 755–7. 5320: 5316: 5310: 5283: 5279: 5269: 5257:. Retrieved 5253:the original 5248: 5238: 5205: 5201: 5195: 5158: 5154: 5114: 5110: 5104: 5071: 5067: 5027: 5023: 4984:(3): 270–6. 4981: 4977: 4929: 4925: 4919: 4886: 4882: 4876: 4855: 4851: 4841: 4829:. Retrieved 4811: 4789:. Retrieved 4778: 4769: 4760:10665/345533 4750: 4741: 4714: 4710: 4658: 4654: 4600: 4596: 4590: 4578:. Retrieved 4561: 4551: 4516: 4512: 4464: 4460: 4410: 4406: 4362:(1): 27–38. 4359: 4355: 4309: 4305: 4295: 4265:(1): 83–92. 4262: 4258: 4222: 4218: 4168: 4164: 4090: 4086: 4034: 4028: 3995: 3991: 3948:(7): 853–8. 3945: 3941: 3935: 3902: 3898: 3875:. Retrieved 3851:(3): 640–9. 3848: 3844: 3784: 3730: 3726: 3682: 3678: 3621:(6): 381–9. 3618: 3614: 3563: 3541:. Retrieved 3532: 3522: 3498: 3445: 3441: 3435: 3425:10 September 3423:. Retrieved 3385: 3381: 3368: 3352: 3347: 3334:. Retrieved 3320: 3308:. Retrieved 3299: 3290: 3266: 3259: 3246: 3230:pain wind-up 3207: 3190:anthelmintic 3187: 3176: 3151: 3146: 3143:Adam Parfrey 3139:psychonautic 3127:D. M. Turner 3123:Marcia Moore 3100: 3077:Class B drug 3029: 3026:Legal status 3009: 2992: 2978: 2969: 2959: 2956:levorotation 2947: 2939: 2925: 2916: 2908: 2894: 2885: 2870: 2815: 2794: 2751: 2732: 2716: 2693:Dissociation 2691: 2665: 2631: 2603:case reports 2569: 2566: 2559: 2554: 2550: 2538: 2534: 2524: 1856:upregulation 1813: 1789: 1785: 1762:, including 1756: 1721: 1708:Pharmacology 1703: 1672: 1669:Interactions 1650:insufflation 1646: 1617: 1586: 1570:interstitial 1539: 1530: 1525:Laryngospasm 1486: 1437:intracranial 1431:hypertension 1412: 1400: 1388: 1376: 1360: 1353: 1338: 1321: 1315: 1309: 1301: 1289: 1270:chronic pain 1259: 1247: 1238: 1229:bronchospasm 1218: 1199: 1172: 1128: 1120:Medical uses 1095: 1087: 1060: 1035: 1034: 1023:   957: 947: 615:33643-49-1 ( 608:33643-46-8 ( 580: 501:Elimination 327:Schedule III 251:Legal status 245:Legal status 96:License data 25: 38907:Euphoriants 38629:amphetamine 38580:antagonists 38526:hydrocodone 38413:Galantamine 38365:Spiradoline 38355:Racemorphan 38340:Phenazocine 38335:Pentazocine 38325:Noribogaine 38290:Levorphanol 38230:Cyclazocine 38225:Butorphanol 38215:Bremazocine 38172:Haloalkanes 38058:Eszopiclone 38016:amphetamine 37975:Pramipexole 37935:Cabergoline 37920:Apomorphine 37718:MDMB-CHMICA 37688:FUB-JWH-018 37683:FUB-APINACA 37578:AB-FUBINACA 37573:AB-CHMINACA 37568:AB-CHFUPYCA 36707:Tolterodine 36702:Scopolamine 36682:Pheniramine 36647:Hyoscyamine 36562:CAR-302,668 36557:CAR-302,537 36552:CAR-302,368 36547:CAR-302,282 36542:CAR-302,196 36537:CAR-301,060 36532:CAR-226,086 36517:BRN-1484501 36507:Benzydamine 36497:Benactyzine 36482:antagonists 36438:Perzinfotel 36433:Noribogaine 36393:Dizocilpine 36342:Racemorphan 36332:Dextrorphan 36289:Diphenidine 36273:Rimantadine 36255:Adamantanes 36236:Gacyclidine 36128:PCP-related 36114:Norketamine 36077:Ethketamine 36046:hexylamines 36033:antagonists 35991:empathogens 35750:Noribogaine 35583:5-Bromo-DMT 35543:4,5-DHP-DMT 35365:Tryptamines 35337:Piperazines 35308:Macromerine 34629:25B-NMe7Ind 34619:25B-NMe7Box 34614:25B-NMe7Bim 34557:MDPEA-NBOMe 34527:5-APB-NBOMe 34512:2CBCB-NBOMe 34421:25TFM-NBOMe 34094:25T7-NB4OMe 34089:25T4-NB4OMe 34084:25T2-NB4OMe 34016:25T7-NB3OMe 34011:25T4-NB3OMe 34006:25T2-NB3OMe 33462:Ergometrine 33324:Benzofurans 33240:Opiates use 33220:Cocaine use 33055:Issues with 32973:Switzerland 32958:South Korea 32928:Puerto Rico 32913:Philippines 32783:El Salvador 32693:Afghanistan 32429:Just Say No 32419:Switzerland 32394:Netherlands 32360:Drug policy 32290:Prohibition 32275:Drug policy 32268:State level 32113:Dance party 32024:Microdosing 31981:Psychedelia 31936:Oktoberfest 31858:Coffeehouse 31835:Stoner film 31526:Scopolamine 31256:Entactogens 31234:Theobromine 31097:Amphetamine 31023:Hydrocodone 31013:Diamorphine 30817:Depressants 30715:from market 30658:brexanolone 30572:risperidone 30469:Moclobemide 30451:Reversible: 30411:Reversible: 30334:Iproclozide 30269:Setiptiline 30264:Mirtazapine 30254:Maprotiline 30211:Propizepine 30196:Noxiptiline 30181:Metapramine 30171:Lofepramine 30141:Dimetacrine 30131:Desipramine 30004:Flupentixol 29989:Etryptamine 29974:Amisulpride 29969:Agomelatine 29915:Etoperidone 29892:Setiptiline 29887:Mirtazapine 29859:Nomifensine 29816:Atomoxetine 29793:Venlafaxine 29783:Milnacipran 29725:Fluvoxamine 29604:from market 29548:Frunevetmab 29528:Bedinvetmab 29437:PF-05089771 29346:Mirogabalin 29307:Ion channel 29277:Cannabidiol 29230:Benzydamine 29173:Pyrazolones 29155:Wintergreen 29105:Ethenzamide 29100:Dipyrocetyl 29057:Salicylates 28999:Lumiracoxib 28935:Indometacin 28863:Zaltoprofen 28782:Propionates 28692:Acetanilide 28683:Paracetamol 28617:Piritramide 28602:Phenazocine 28597:Phenadoxone 28587:Pentazocine 28582:Oliceridine 28577:Norpipanone 28546:+fluanisone 28527:Dimenoxadol 28507:Carfentanil 28502:Bezitramide 28497:Anileridine 28466:Papaveretum 28461:Oxymorphone 28455:+naltrexone 28417:Nicocodeine 28402:Levorphanol 28371:Hydrocodone 28328:Butorphanol 28273:+naltrexone 28156:from market 28023:Embutramide 28018:Anileridine 27990:Remimazolam 27927:Amobarbital 27904:Fospropofol 27867:Vinyl ether 27857:Sevoflurane 27699:Venlafaxine 27679:Remoxipride 27669:Propranolol 27594:Cinnarizine 27494:Lamotrigine 27390:Pentazocine 27385:Noribogaine 27375:Nemonapride 27207:Haloperidol 27133:Spipethiane 27098:Noribogaine 27093:Nemonapride 27088:KCR-12-83.1 26928:Pentazocine 26888:Haloperidol 26793:Pridopidine 26768:Pentazocine 26685:Fluvoxamine 26605:Cyclazocine 26362:Kelatorphan 26339:Candoxatril 26228:Antagonists 26179:Racemorphan 26146:NNC 63-0532 26131:Lexanopadol 26126:Levorphanol 26004:Quadazocine 25989:Pawhuskin A 25984:Noribogaine 25974:Navacaprant 25964:Naltrindole 25884:Epicatechin 25849:Clocinnamox 25732:Antagonists 25694:desipramine 25661:Samidorphan 25631:Racemorphan 25616:Phenazocine 25606:Pentazocine 25586:Norketamine 25581:Noribogaine 25541:Nalfurafine 25506:Mirtazapine 25496:Metkefamide 25456:Lexanopadol 25451:Levorphanol 25431:Laudanosine 25416:ICI-204,448 25411:ICI-199,441 25381:Hemorphin-4 25341:Erinacine E 25326:Eluxadoline 25316:Dynorphin A 25261:Cyclazocine 25236:Butorphanol 25221:Bremazocine 25196:Asimadoline 25186:Allomatrine 25176:Akuammicine 25085:Quadazocine 25080:Pawhuskin A 25075:Noribogaine 25060:Naltrindole 25000:Epicatechin 24995:Eluxadoline 24970:Clocinnamox 24898:Antagonists 24829:Samidorphan 24819:Racemorphan 24799:Oxymorphone 24759:Mitragynine 24754:Metkefamide 24734:Lexanopadol 24729:Levorphanol 24714:Laudanosine 24679:Hydrocodone 24674:Hemorphin-4 24574:Cyclazocine 24549:Butorphanol 24524:β-Endorphin 24443:Samidorphan 24438:Quadazocine 24428:Pawhuskin A 24418:Noribogaine 24408:Naltrindole 24343:Naldemedine 24273:Epicatechin 24230:Clocinnamox 24118:Antagonists 24089:Tubotaiwine 24074:Trimebutine 24004:Racemorphan 23974:Piritramide 23959:Phenazocine 23944:Pentazocine 23917:Oxymorphone 23882:Oliceridine 23867:Norketamine 23852:Nicocodeine 23837:Naltalimide 23802:Mitragynine 23792:Metkefamide 23762:Loxicodegol 23752:Lexanopadol 23747:Levorphanol 23722:Laudanosine 23687:Hydrocodone 23682:Hodgkinsine 23672:Hemorphin-4 23662:Frakefamide 23622:Embutramide 23617:Dynorphin A 23577:Eluxadoline 23567:Dimenoxadol 23502:Carfentanil 23487:Butorphanol 23462:Bezitramide 23432:β-Endorphin 23422:Anileridine 23412:Akuammidine 23407:Akuammicine 23377:α-Narcotine 23259:Adrenergics 23186:Valbenazine 23176:Rose bengal 23121:Deserpidine 23092:amphetamine 23042:levorphanol 22986:Dextrorphan 22939:ziprasidone 22921:pheniramine 22856:Lofepramine 22836:Desipramine 22785:Tesofensine 22775:Sibutramine 22750:Perafensine 22710:JNJ-7925476 22705:Indatraline 22650:Dasotraline 22620:Amifitadine 22599:Venlafaxine 22579:Milnacipran 22478:Etoperidone 22458:Seproxetine 22448:Pirandamine 22428:Omiloxetine 22408:Fluvoxamine 22368:Cericlamine 22358:Alaproclate 22305:levorphanol 22234:ziprasidone 22216:pheniramine 22188:Setiptiline 22173:Maprotiline 22132:Lofepramine 22112:Desipramine 22061:Tesofensine 22051:Sibutramine 22026:Perafensine 21986:JNJ-7925476 21981:Indatraline 21926:Dasotraline 21896:Amifitadine 21875:Venlafaxine 21850:Milnacipran 21779:Nomifensine 21744:Fencamfamin 21673:Lortalamine 21663:Edivoxetine 21653:Ciclazindol 21648:Alseroxylon 21596:Venlafaxine 21576:Tametraline 21566:Sibutramine 21541:Perafensine 21521:Nomifensine 21451:Indatraline 21426:Fencamfamin 21401:DOV-216,303 21396:DOV-102,677 21356:Dasotraline 21351:Ciclazindol 21309:Armodafinil 21304:Amifitadine 21253:Tesofensine 21061:Difemetorex 20837:Pentamidine 20822:Minocycline 20802:Hodgkinsine 20772:Dexanabinol 20702:Sevoflurane 20556:Isoxsuprine 20551:Haloperidol 20531:Besonprodil 20492:Rimantadine 20442:Norketamine 20437:Noribogaine 20412:Milnacipran 20377:Levorphanol 20327:Gacyclidine 20297:Dizocilpine 20292:Diphenidine 20282:Dextrorphan 20202:Alaproclate 20145:Huperzine A 20098:Meprobamate 20058:Harkoseride 19953:Perzinfotel 19830:Plazinemdor 19377:Kainic acid 19362:Domoic acid 19308:Minocycline 19296:Sevoflurane 18973:Willardiine 18948:Domoic acid 18425:Triamterene 18379:Poneratoxin 18369:Ciguatoxins 18256:Raxatrigine 18251:Ralfinamide 18246:PF-05089771 18241:PF-04531083 18213:Analgesics: 18171:Piperocaine 18156:Meprylcaine 18151:Mepivacaine 18106:Cinchocaine 18085:Ropivacaine 18077:Bupivacaine 18004:Sipatrigine 17989:Pheneturide 17984:Phenacemide 17969:Mephenytoin 17954:Lamotrigine 17934:Elpetrigine 17889:Propafenone 17834:Dronedarone 17410:Tolbutamide 17400:Repaglinide 17395:Nateglinide 17390:Mitiglinide 17370:Glisoxepide 17355:Glimepiride 17345:Glicaramide 17325:Carbutamide 17227:Linopirdine 17210:Vernakalant 17200:Tolterodine 17190:Terfenadine 17180:Tamulotoxin 17175:Solifenacin 17145:PNU-282,987 17120:Haloperidol 17115:Gigactonine 17095:Domperidone 17080:Darifenacin 17045:Bedaquiline 17030:Azaspiracid 16993:Vernakalant 16928:Linopirdine 16888:Dronedarone 16878:Dendrotoxin 16863:Clamikalant 16735:Tolperisone 16730:Tetrandrine 16720:Sipatrigine 16715:Silperisone 16700:Prenylamine 16640:Lidoflazine 16595:Elpetrigine 16505:Mirogabalin 16409:Lamotrigine 16404:Flunarizine 16399:Efonidipine 16389:Cinnarizine 16384:Cilnidipine 16339:NNC 55-0396 16265:Ralfinamide 16212:Fantofarone 16207:Dronedarone 16192:Budiodarone 16187:Brinazarone 16150:Levemopamil 16050:Sornidipine 16045:Sagandipine 16035:Pranidipine 16010:Nisoldipine 16000:Nilvadipine 15990:Niguldipine 15980:Nicardipine 15945:Lemildipine 15930:Iganidipine 15925:Furnidipine 15890:Cronidipine 15885:Clevidipine 15880:Barnidipine 15870:Aranidipine 15725:Adrenergics 15629:Pridopidine 15614:Nafadotride 15599:Metergoline 15514:Alpiropride 15462:Trazpiroben 15432:Hydroxyzine 15427:Eticlopride 15422:Domperidone 15392:Alimemazine 15366:Ziprasidone 15361:Zicronapine 15356:Veralipride 15341:Tefludazine 15331:Risperidone 15326:Remoxipride 15311:Pipotiazine 15301:Perospirone 15290:+fluoxetine 15281:Ocaperidone 15276:Mosapramine 15261:Mazapertine 15251:Iloperidone 15246:Gevotroline 15236:Flumezapine 15216:Cyamemazine 15201:Clorotepine 15181:Blonanserin 15166:Amisulpride 15120:Thiothixene 15055:Pipamperone 15020:Perathiepin 15015:Penfluridol 15010:Nemonapride 14965:Haloperidol 14944:+melitracen 14910:Clopimozide 14860:Bromperidol 14829:Antagonists 14820:WAY-100,635 14765:Quinelorane 14760:Quinagolide 14740:Pramipexole 14705:Pardoprunox 14690:Mesulergine 14680:Flibanserin 14670:Dizocilpine 14650:Armodafinil 14640:Apomorphine 14584:Cariprazine 14558:+sertraline 14499:Etilevodopa 14422:Ergocornine 14417:Epicriptine 14402:Cabergoline 14355:Rimantadine 14341:Adamantanes 14262:Ziprasidone 14257:Zicronapine 14252:Tefludazine 14247:Risperidone 14231:+fluoxetine 14212:Iloperidone 14187:Clorotepine 14156:Thiothixene 14146:Pifluthixol 14120:+melitracen 14090:Antagonists 13996:Apomorphine 13941:Etilevodopa 13915:Doxanthrine 13905:Dinapsoline 13844:Cabergoline 13685:Pirisudanol 13650:Cyprodenate 13630:Adafenoxate 13545:Surugatoxin 13535:Sevoflurane 13490:Pentolinium 13470:Norketamine 13390:Laudanosine 13320:Erythravine 13310:Encenicline 13295:Dipyrandium 13265:Dextrorphan 13111:α-conotoxin 13070:Antagonists 13055:WAY-317,538 13050:Varenicline 13040:Tropisetron 13030:Tebanicline 12975:SSR-180,711 12940:Rivanicline 12930:Pozanicline 12925:PNU-282,987 12920:PNU-120,596 12915:PHA-709,829 12910:PHA-543,613 12850:Galantamine 12825:Epiboxidine 12820:Epibatidine 12740:Altinicline 12573:Pirisudanol 12538:Cyprodenate 12518:Adafenoxate 12483:Zamifenacin 12467:+vilanterol 12423:Tropicamide 12418:Tropatepine 12403:Trimebutine 12363:lofepramine 12339:desipramine 12306:Tolterodine 12275:mirtazapine 12267:maprotiline 12249:Telenzepine 12225:Solifenacin 12200:SCH-217,443 12175:Revefenacin 12160:Propiverine 12120:Piroheptine 12115:Pirenzepine 12080:Penthienate 11965:Mepenzolate 11960:Meladrazine 11935:Hyoscyamine 11919:+salbutamol 11905:Homatropine 11890:Hexocyclium 11747:Darifenacin 11707:CAR-302,668 11702:CAR-302,537 11697:CAR-302,368 11692:CAR-302,282 11687:CAR-302,196 11682:CAR-301,060 11677:CAR-226,086 11647:Benzydamine 11627:Benactyzine 11605:+fluoxetine 11552:pheniramine 11540:mequitazine 11524:dimetindene 11508:cinnarizine 11478:Anisodamine 11452:+formoterol 11430:Antagonists 11410:WAY-132,983 11380:Vedaclidine 11350:SDZ 210-086 11345:Sabcomeline 11335:Pilocarpine 11205:Bethanechol 10963:27 November 10935:26 December 10628:6 September 10598:6 September 10555:. Toronto: 10533:28 December 10407:Feral House 10403:Los Angeles 10319:. pp.  10257:. pp.  10230:. pp.  10109:Marshall DR 10060:21 February 9794:(1): 9–24. 9571:R. Baselt, 8861:(1): 2–12. 8439:: 279–292. 7511:13 November 7008:: 135–137. 6758:: 568–575. 6529:11 February 6410:2268/231971 6035:10871/30208 4413:: 831–841. 3841:"Ketamine*" 3336:29 December 3242:guaifenesin 3198:albendazole 3135:entheogenic 3005:Vietnam War 2989:Parke-Davis 2954:salt shows 2829:methylamine 2801:metabolites 2773:norketamine 2735:distributed 2719:Intravenous 2595:metabolites 1772:rislenemdaz 1752:spinal cord 1748:dorsal horn 1724:enantiomers 1691:lamotrigine 1675:potentiates 1656:. Ketamine 1497:lamotrigine 1441:intraocular 1413:Some major 1195:hypotension 1175:Vietnam War 1148:lamotrigine 1135:respiratory 1110:Vietnam War 960:(−)-isomer) 950:(+)-isomer) 905: g·mol 851:100.027.095 563:Identifiers 456:Norketamine 449:Metabolites 364:Intravenous 69:Other names 60:Trade names 38867:Analgesics 38861:Categories 38803:suvorexant 38727:prednisone 38680:carbamates 38641:mephedrone 38584:perampanel 38567:pregabalin 38563:gabapentin 38434:Isoaminile 38395:Oneirogens 38345:Proxorphan 38330:Oxilorphan 38320:Nalorphine 38310:Nalbuphine 38300:Metazocine 38275:Ketazocine 38255:Herkinorin 38235:Cyclorphan 38182:Chloroform 38024:precursors 37985:Rotigotine 37980:Ropinirole 37955:Nuciferine 37763:NESS-040C5 37643:CUMYL-PICA 37603:ADB-PINACA 37543:5F-SDB-006 37523:5F-APINACA 36677:Oxybutynin 36667:Mepyramine 36617:Doxylamine 36577:Clemastine 36472:Deliriants 36448:Remacemide 36423:Neramexane 36403:Herkinorin 36388:Dexoxadrol 36383:Delucemine 36314:Morphinans 36294:Ephenidine 36263:Amantadine 36170:3-MeO-PCPy 36165:3-MeO-PCPr 36155:3-MeO-PCMo 36135:2'-Oxo-PCE 36119:Tiletamine 36083:Esketamine 36066:Arketamine 36044:Arylcyclo‐ 36005:and other 35975:Lorcaserin 35900:Baeocystin 35890:5-MeO-MPMI 35885:5-MeO-MALT 35880:5-MeO-EiPT 35760:Voacangine 35516:5-MeO-DiPT 35437:5-MeO-DALT 35395:5-MeO-α-MT 35390:5-MeO-α-ET 35141:Proscaline 35121:Jimscaline 34990:Lophophine 34654:25I-NMeTHF 34649:25I-NMeFur 34639:25B-NMePyr 34609:25B-NMe7BT 34604:25B-NMe7BF 34552:FECIMBI-36 34522:4-EA-NBOMe 34502:25I-NBMeOH 34487:25I-NB34MD 34482:25I-N4MT3M 34477:25I-N3MT2M 34467:25C-NBOiPr 34452:25B-NB25DM 34447:25B-NB23DM 34442:25B-NAcPip 34437:25B-N1POMe 34416:25T7-NBOMe 34411:25T4-NBOMe 34406:25T2-NBOMe 34386:25iP-NBOMe 34351:25CN-NBOMe 34318:25TFM-NBOH 34240:25TFM-NBMD 34079:25P-NB4OMe 34074:25N-NB4OMe 34069:25I-NB4OMe 34064:25H-NB4OMe 34059:25E-NB4OMe 34054:25D-NB4OMe 34049:25C-NB4OMe 34044:25B-NB4OMe 34001:25P-NB3OMe 33996:25N-NB3OMe 33991:25I-NB3OMe 33986:25H-NB3OMe 33981:25E-NB3OMe 33976:25D-NB3OMe 33971:25C-NB3OMe 33966:25B-NB3OMe 33557:Phenethyl‐ 33407:1cP-AL-LAD 33397:1P-ETH-LAD 33347:5-MeO-DiBF 33228:Annual use 33079:Dependence 32943:Seychelles 32848:Kyrgyzstan 32763:Costa Rica 32708:Bangladesh 32681:Drug trade 32650:production 32639:production 32558:Drug court 32444:California 32362:by country 32295:Regulation 32029:Smart shop 32014:Literature 32009:Experience 31956:Sports bar 31921:Happy hour 31886:Bartending 31657:Club drugs 31630:Oneirogens 31514:Deliriants 31394:Psilocybin 31217:Polacrilex 31187:Mephedrone 31089:Stimulants 30891:Hazardous 30835:Carbamates 30690:Tryptophan 30662:zuranolone 30568:quetiapine 30564:olanzapine 30560:lurasidone 30514:Selegiline 30504:-selective 30484:Toloxatone 30479:Tetrindole 30474:Pirlindole 30454:Eprobemide 30444:-selective 30424:Bifemelane 30414:Caroxazone 30374:Phenelzine 30359:Mebanazine 30339:Iproniazid 30226:Tianeptine 30206:Pipofezine 30176:Melitracen 30156:Imipramine 30136:Dibenzepin 30096:Amineptine 30044:Tianeptine 30029:Pivagabine 30024:Oxaflozane 29984:Esketamine 29948:Vilazodone 29920:Nefazodone 29849:Amineptine 29826:Viloxazine 29821:Reboxetine 29773:Duloxetine 29745:Zimelidine 29740:Sertraline 29735:Paroxetine 29720:Fluoxetine 29710:Citalopram 29578:Rimazolium 29573:Proglumide 29518:Analgecine 29455:Flupirtine 29398:Mexiletine 29379:Lacosamide 29356:Ziconotide 29351:Pregabalin 29341:Leconotide 29331:Gabapentin 29309:modulators 29292:Nabiximols 29255:Proquazone 29250:Nimesulide 29245:Nabumetone 29196:Nifenazone 29110:Guacetisal 29095:Diflunisal 29080:Benorylate 29014:Valdecoxib 28994:Etoricoxib 28925:Diclofenac 28915:Acemetacin 28884:Lornoxicam 28838:Loxoprofen 28825:Ketoprofen 28794:Fenoprofen 28759:Phenacetin 28737:+oxycodone 28727:+ibuprofen 28659:+celecoxib 28642:Tapentadol 28637:Sufentanil 28612:Piminodine 28562:Meptazinol 28557:Lofentanil 28532:Dipipanone 28487:Alfentanil 28447:+ibuprofen 28412:Nalbuphine 28382:+ibuprofen 28214:Analgesics 28131:Propanidid 28105:Alfaxalone 28100:Alfadolone 28082:Tiletamine 28067:Esketamine 28049:Sufentanil 28033:Alfentanil 27952:Thiopental 27837:Isoflurane 27807:Desflurane 27797:Chloroform 27684:SL 82.0715 27599:Cinuperone 27574:Caramiphen 27569:Butaclamol 27469:Tapentadol 27400:Safinamide 27380:Nepinalone 27345:Clemastine 27340:5-MeO-DiPT 27335:5-MeO-DALT 27212:Ifenprodil 27177:Arketamine 27128:Selegiline 27123:Safinamide 27083:Imipramine 27045:Clorgiline 27035:Clemastine 27025:Azidopamil 27015:5-MeO-DiPT 27010:5-MeO-DALT 26943:Sertraline 26743:Nepinalone 26690:Ifenprodil 26680:Fluoxetine 26645:Dimemorfan 26614:prasterone 26575:Citalopram 26570:Captodiame 26550:Arketamine 26545:Amantadine 26503:modulators 26457:Kyotorphin 26402:Spinorphin 26283:SB-612,111 26278:Nocistatin 26248:BAN-ORL-24 26199:SCH-486757 26194:SCH-221510 26033:Nociceptin 25994:PF-4455242 25969:Naringenin 25959:Naltrexone 25919:LY-2795050 25914:LY-2459989 25909:LY-2444296 25904:LY-2196044 25889:Hyperoside 25804:Aticaprant 25698:imipramine 25621:Proxorphan 25596:Oxilorphan 25566:Niravoline 25556:Nalorphine 25531:Nalbuphine 25516:Moxazocine 25491:Metazocine 25461:Lofentanil 25426:Ketazocine 25386:Herkinorin 25366:Gemazocine 25356:Fedotozine 25336:Eptazocine 25266:Cyclorphan 25251:Ciprefadol 25070:Naringenin 25050:Naltrexone 25045:Nalorphine 25020:LY-2196044 25010:ICI-174864 25005:ICI-154129 24950:Bevenopran 24925:α-Santolol 24889:Zenazocine 24869:Tonazocine 24824:RWJ-394674 24809:Proglumide 24749:Metazocine 24739:Lofentanil 24669:Fluorophen 24433:Rimonabant 24423:Oxilorphan 24413:Naringenin 24403:Naltrexone 24368:Naloxazone 24358:Nalorphine 24323:LY-2196044 24293:Hyperoside 24283:Gemazocine 24278:Eptazocine 24215:Bevenopran 24059:Tianeptine 24034:Tapentadol 24029:Sufentanil 24024:Sinomenine 24014:Salsolinol 23969:Piminodine 23887:Oxycodegol 23877:Octreotide 23872:Nufenoxole 23822:Nalbuphine 23777:Meptazinol 23757:Loperamide 23727:Lefetamine 23677:Herkinorin 23657:Fluorophen 23612:Dipipanone 23537:Dermorphin 23427:Apparicine 23417:Alfentanil 23340:(abridged; 23320:modulators 23235:SoRI-20041 23228:SoRI-20040 23156:Ketanserin 23083:Amiodarone 23046:tapentadol 23006:Mesembrine 22976:Delucemine 22953:esketamine 22866:Pipofezine 22851:Imipramine 22770:SEP-228432 22765:SEP-228431 22735:Nefazodone 22720:Liafensine 22690:Fezolamine 22680:DOV-216303 22675:DOV-102677 22630:Bicifadine 22625:Ansofaxine 22564:Eclanamine 22559:Duloxetine 22544:Bicifadine 22518:Vilazodone 22488:Lubazodone 22483:Litoxetine 22468:Zimelidine 22463:Sertraline 22438:Paroxetine 22433:Panuramine 22403:Fluoxetine 22398:Femoxetine 22378:Dapoxetine 22373:Citalopram 22297:tapentadol 22276:Nefazodone 22259:Ephenidine 22254:Dopexamine 22137:Melitracen 22127:Imipramine 22046:SEP-228432 22041:SEP-228431 22011:Nefazodone 21996:Liafensine 21966:Fezolamine 21956:DOV-216303 21951:DOV-102677 21906:Bicifadine 21901:Ansofaxine 21860:Nafenodone 21835:Eclanamine 21830:Duloxetine 21789:Radafaxine 21769:Manifaxine 21754:Lefetamine 21729:Amineptine 21713:Viloxazine 21688:Reboxetine 21683:Nisoxetine 21561:Sertraline 21551:Radafaxine 21536:Oroxylin A 21481:Manifaxine 21471:Liafensine 21461:Lefetamine 21441:GYKI-52895 21431:Fezolamine 21416:Esketamine 21411:Ephenidine 21334:BTS 74,398 21324:Ansofaxine 21319:Amineptine 21198:FP-β-CPPIT 21193:FE-β-CPPIT 21132:Prolintane 21025:Vanoxerine 21020:Nefazodone 20875:AGN-241751 20847:Piretanide 20797:Furosemide 20782:Flupirtine 20759:Conantokin 20754:Caroverine 20749:Bumetanide 20682:Isoflurane 20652:Desflurane 20642:Chloroform 20581:Safaprodil 20576:Ro 25-6981 20517:Tiletamine 20502:Sabeluzole 20482:Remacemide 20427:Neramexane 20397:Methorphan 20382:Loperamide 20357:Lanicemine 20342:Indantadol 20307:Esketamine 20302:Ephenidine 20262:Dexoxadrol 20227:Arketamine 20212:Amantadine 20172:3-MeO-PCMo 20150:Putrescine 20093:MDL-105519 20068:Kynurenine 20048:Gavestinel 19963:SDZ-220581 19923:MDL-100453 19806:prasterone 19776:Spermidine 19749:Milacemide 19654:ACC (ACPC) 19540:Evans blue 19504:Topiramate 19494:Tezampanel 19424:Isoflurane 19301:Talampanel 19286:Perampanel 19281:Isoflurane 19266:GYKI-53655 19261:GYKI-52466 19256:Evans blue 19220:Zonampanel 19210:Topiramate 19200:Tezampanel 19175:Kynurenine 19135:Caroverine 19130:Becampanel 19080:Oxiracetam 18980:Aniracetam 18901:modulators 18729:Bumetanide 18667:Activators 18657:Piretanide 18652:Lonidamine 18603:Activators 18588:Mibefradil 18583:Mefloquine 18573:Furosemide 18568:Fluoxetine 18548:Crofelemer 18435:Activators 18358:Versutoxin 18354:Robustoxin 18336:Activators 18321:Safinamide 18271:Conotoxins 18206:Trimecaine 18201:Tetracaine 18176:Prilocaine 18166:Orthocaine 18141:Iontocaine 18136:Hexylcaine 18131:Etidocaine 18072:Benzocaine 18062:Amylocaine 18044:Zonisamide 18039:Valpromide 18009:Topiramate 17999:Rufinamide 17959:Lacosamide 17924:Cenobamate 17879:Prajmaline 17869:Moricizine 17864:Mexiletine 17859:Lorcainide 17844:Flecainide 17809:Ranolazine 17749:Activators 17734:Fluoxetine 17678:Nimesulide 17660:-specific: 17646:Activators 17628:-specific: 17580:-specific: 17560:Rilmakalim 17550:Nicorandil 17510:Cromakalim 17497:-specific: 17478:Activators 17468:Tipepidine 17458:Ifenprodil 17433:Caramiphen 17425:-specific: 17405:Tolazamide 17365:Gliquidone 17350:Gliclazide 17317:-specific: 17270:Retigabine 17265:Flupirtine 17262:-specific: 17247:Activators 17224:-specific: 17205:Vanoxerine 17185:Terodiline 17170:Sertindole 17160:Ranolazine 17025:Astemizole 17015:Amiodarone 16983:Terikalant 16958:Pinokalant 16943:Nifekalant 16938:Maurotoxin 16933:Lolitrem B 16923:Kaliotoxin 16883:Dofetilide 16873:Dalazatide 16868:Conotoxins 16838:Amiodarone 16833:Almokalant 16755:Activators 16745:Valperinol 16725:Terodiline 16665:Naftopidil 16655:Mesuximide 16585:Enpiperate 16565:Cycleanine 16550:Bevantolol 16540:Bencyclane 16530:Pregabalin 16520:PD-299,685 16515:PD-217,014 16510:PD-200,347 16500:Imagabalin 16490:Gabapentin 16480:Atagabalin 16470:Arbaclofen 16429:Mibefradil 16424:Loperamide 16419:Lomerizine 16394:Dotarizine 16374:Benidipine 16354:Zonisamide 16270:Safinamide 16245:Caroverine 16197:Celivarone 16145:Gallopamil 16100:Siratiazem 16090:Iprotiazem 16080:Clentiazem 16060:Tiamdipine 16055:Teludipine 16020:Olradipine 16005:Nimodipine 15995:Niludipine 15985:Nifedipine 15975:Mesudipine 15965:Manidipine 15940:Lacidipine 15935:Isradipine 15920:Flordipine 15915:Felodipine 15910:Elnadipine 15905:Elgodipine 15895:Darodipine 15865:Amlodipine 15634:Raclopride 15624:PNU-99,194 15619:Nuciferine 15559:Fananserin 15554:Fallypride 15483:Nefazodone 15412:Clebopride 15407:Bromopride 15397:Alizapride 15351:Tiospirone 15346:Tenilapine 15336:Sertindole 15321:Quetiapine 15316:Piquindone 15286:Olanzapine 15256:Lurasidone 15226:Dixyrazine 15191:Cinuperone 15150:Zetidoline 15125:Timiperone 15100:Teflutixol 15095:Sultopride 14935:Fluotracen 14930:Flucindole 14925:Fluanisone 14920:Fluacizine 14915:Droperidol 14895:Ciclindole 14865:Butaclamol 14855:Benperidol 14815:Umespirone 14810:Talipexole 14805:Sumanirole 14800:SKF-83,959 14785:Ropinirole 14770:Quinpirole 14725:PF-592,379 14720:PF-219,061 14715:PD-168,077 14710:PD-128,907 14675:Esketamine 14665:CP-226,269 14660:Captodiame 14645:Arketamine 14569:Bifeprunox 14533:Melevodopa 14494:Dopexamine 14473:Dinoxyline 14427:Lergotrile 14381:Rotigotine 14345:Amantadine 14242:Quetiapine 14227:Olanzapine 14192:Clotiapine 14101:Butaclamol 14036:SKF-89,626 14031:SKF-89,145 14026:Rotigotine 14016:PF 6669571 14011:PF-6649751 14006:Nuciferine 13959:Melevodopa 13936:Dopexamine 13910:Dinoxyline 13849:CY-208,243 13833:Zelandopam 13823:SKF-83,959 13818:SKF-82,958 13813:SKF-81,297 13808:SKF-77,434 13803:SKF-38,393 13798:Fenoldopam 13762:modulators 13645:Citicoline 13625:Acetyl-coA 13609:Precursors 13585:Vanoxerine 13575:Tropeinium 13560:Toxiferine 13525:Reboxetine 13515:Radafaxine 13460:Neramexane 13450:Mivacurium 13445:Metocurine 13410:Malouetine 13375:Isoflurane 13330:Fazadinium 13325:Esketamine 13305:Doxacurium 13290:Dioscorine 13250:Desflurane 13215:Coclaurine 13147:Atracurium 13132:Amantadine 13122:Alcuronium 12875:Levamisole 12865:Ivermectin 12810:Dianicline 12770:Butinoline 12755:Anatoxin-a 12644:modulators 12533:Citicoline 12513:Acetyl-coA 12497:Precursors 12478:Xanomeline 12359:imipramine 12347:dibenzepin 12254:Terodiline 12243:paroxetine 12239:femoxetine 12195:SCH-72,788 12190:SCH-57,790 12180:Rociverine 12075:PD-0298029 12070:PD-102,807 12050:Oxybutynin 11955:Mebeverine 11900:HL-031,120 11885:Hexbutinol 11827:Etanautine 11782:Difemerine 11762:Dexetimide 11712:Caramiphen 11667:Bornaprine 11617:tenilapine 11613:quetiapine 11601:olanzapine 11532:doxylamine 11512:clemastine 11500:captodiame 11458:Abediterol 11415:Xanomeline 11405:VU-0238429 11400:VU-0152100 11395:VU-0152099 11390:VU-0090157 11385:VU-0029767 11370:Tazomeline 11330:PD-151,832 11320:Ocvimeline 11305:Milameline 11280:LY-593,039 11245:Cevimeline 11190:Alvameline 11165:Aceclidine 11160:AC-260,584 11150:77-LH-28-1 11120:modulators 11077:modulators 10753:(1): 527. 10309:Horowitz M 10307:Palmer C, 10185:Drug Abuse 9683:"Ketamine" 9324:(7): 778. 8634:: 114210. 6452:(5): 470. 6121:18 January 5776:(1): 245. 5684:: 749837. 4812:StatPearls 4791:1 December 4562:StatPearls 3328:. US DEA. 3251:References 3238:thiopental 3234:detomidine 3194:ivermectin 3062:Schedule X 2913:arketamine 2905:esketamine 2769:isoenzymes 2754:metabolism 2684:receptor. 2677:raclopride 2547:affinities 2367:Antagonist 2340:Antagonist 2309:Antagonist 2278:Antagonist 2247:Antagonist 2216:Antagonist 2180:Antagonist 2044:Antagonist 2008:Antagonist 1976:Antagonist 1947:Antagonist 1796:metabolite 1776:rapastinel 1768:lanicemine 1732:arketamine 1728:esketamine 1695:nimodipine 1687:Naltrexone 1662:withdrawal 1578:urothelium 1521:hypertonia 1501:nimodipine 1435:Increased 1367:compounded 1317:esketamine 1312:enantiomer 1284:See also: 1280:Depression 1152:nimodipine 1125:Anesthesia 1048:depression 1044:anesthesia 954:Arketamine 944:Esketamine 910:3D model ( 898:Molar mass 781:CHEBI:6121 758:HCl:  733:690G0D6V8H 704:ChemSpider 664:IUPHAR/BPS 625:HCl:  617:arketamine 610:esketamine 593:CAS Number 572:IUPAC name 420:Metabolism 414:23 to 47%. 388:Sublingual 382:Intranasal 302:Anlage III 291:Schedule I 193:Drug class 38947:Sedatives 38816:See also: 38793:inhalants 38749:areca nut 38745:arecoline 38714:analogues 38692:inhalants 38603:) (e.g., 38561:) (e.g., 38548:δ subunit 38530:oxycodone 38516:) (e.g., 38449:Pukateine 38439:Noscapine 38385:Xorphanol 38370:Tifluadom 38315:Nalmefene 38250:Enadoline 38220:Butorphan 38210:Alazocine 38165:Enflurane 38100:Inhalants 38090:Zopiclone 38046:enhancers 37970:Piribedil 37960:Pergolide 37950:Memantine 37925:Aporphine 37793:Parahexyl 37788:Org 28611 37758:NESS-0327 37733:MEPIRAPIM 37693:FUB-PB-22 37673:FDU-PB-22 37583:AB-PINACA 37553:A-836,339 37548:A-796,260 37513:5F-ADBICA 37488:4-HTMPIPO 37063:CP 55,940 37058:CP 55,244 37053:CP 47,497 36792:Synthetic 36755:agonists) 36662:Meclozine 36642:Flavoxate 36587:Cyclizine 36512:Biperiden 36413:Midafotel 36398:Etoxadrol 36373:Aptiganel 36268:Memantine 36175:4-MeO-PCP 36160:3-MeO-PCP 36150:3-MeO-PCE 35965:Efavirenz 35960:Dimemebfe 35950:AL-38022A 35865:4-HO-McPT 35829:5-Me-MiPT 35792:5-MeO-MET 35740:Ibogamine 35699:5-MeO-DPT 35642:α,N,N-TMT 35637:7,N,N-TMT 35619:5-MeO-DMT 35578:5-AcO-DMT 35563:4,N,N-TMT 35553:4-AcO-DMT 35548:2,N,N-TMT 35479:(T-9) DET 35474:5-MeO-DET 35126:Mescaline 35081:Buscaline 34659:25I-NMeTh 34547:DOI-NBOMe 34542:DOB-NBOMe 34537:C30-NBOMe 34532:5MT-NBOMe 34507:25I-NBTFM 34462:25C-NBOEt 34401:25T-NBOMe 34396:25P-NBOMe 34391:25N-NBOMe 34381:25I-NBOMe 34376:25H-NBOMe 34371:25G-NBOMe 34366:25F-NBOMe 34361:25E-NBOMe 34356:25D-NBOMe 34346:25C-NBOMe 34341:25B-NBOMe 34313:25T7-NBOH 34308:25T2-NBOH 34273:25CN-NBOH 34235:25T7-NBMD 34230:25T2-NBMD 34167:25TFM-NBF 33834:2C-T-22.5 33542:PARGY-LAD 33412:1cP-MiPLA 33342:5-MeO-BFE 33315:agonists) 33224:Cannabis 33069:Addiction 33025:Beer shop 33008:Venezuela 32873:Mauritius 32703:Australia 32641:and trade 32568:Drug test 32369:Australia 32143:Nootropic 32128:Entheogen 32103:Club drug 31951:Sommelier 31946:Pub crawl 31931:Nightclub 31926:Hip flask 31863:Latte art 31800:Head shop 31670:Quaaludes 31438:Inhalants 31387:San Pedro 31372:Mescaline 31355:Ayahuasca 31328:Bufotenin 31273:Benzofury 31264:2C series 31244:Chocolate 31207:Modafinil 31197:Methylone 31170:Ephedrine 31141:Cathinone 31102:Arecoline 31067:Oxycodone 31038:Methadone 30872:Inhalants 30725:Phase III 30713:Withdrawn 30578:Buspirone 30464:Minaprine 30399:Tedizolid 30394:Safrazine 30369:Octamoxin 30364:Nialamide 30354:Linezolid 30349:Isoniazid 30259:Mianserin 30201:Opipramol 30166:Iprindole 30146:Dosulepin 30111:Amoxapine 30067:Tricyclic 29925:Trazodone 29882:Mianserin 29854:Bupropion 29788:Tofenacin 29730:Indalpine 29679:Specific 29614:Phase III 29602:Withdrawn 29583:Tanezumab 29543:Clonidine 29538:Capsaicin 29392:lidocaine 29240:Glafenine 29201:Phenazone 29145:Salsalate 29075:Aloxiprin 29024:Fenamates 29009:Rofecoxib 29004:Parecoxib 28988:+tramadol 28981:Celecoxib 28963:Zomepirac 28948:Ketorolac 28920:Bromfenac 28899:Tenoxicam 28894:Piroxicam 28889:Meloxicam 28848:Oxaprozin 28804:Ibuprofen 28747:+tramadol 28702:Butacetin 28567:Methadone 28480:Synthetic 28451:+naloxone 28432:Oxycodone 28361:Etorphine 28322:+naloxone 28289:Paregoric 28166:Phase III 28154:Withdrawn 28126:Etomidate 28013:Oxycodone 27985:Lorazepam 27975:Midazolam 27947:Thiamylal 27882:Injection 27832:Halothane 27827:Fluroxene 27817:Enflurane 27711:See also: 27689:SR-31747A 27674:Quinidine 27659:Proadifen 27644:Molindone 27619:Hypericin 27614:EMD-59983 27564:BMY-13980 27549:SKF-83959 27464:Naluzotan 27444:Berberine 27441:Agonists: 27395:RS-67,333 27330:4-MeO-PCP 27325:3-MeO-PCE 27240:Opipramol 27235:OPC-14523 27169:Agonists: 27108:RS-67,333 27053:-Deprenyl 27005:4-MeO-PCP 26985:3-MeO-PCP 26970:SOMCL-668 26962:Positive: 26958:Phenytoin 26948:SR-31742A 26923:PD-144418 26913:NPC-16377 26763:Opipramol 26758:OPC-14523 26753:Noscapine 26723:Memantine 26665:Eliprodil 26660:Donepezil 26535:5-MeO-DMT 26522:Agonists: 26412:Tynorphin 26407:Thiorphan 26387:Opiorphan 26329:Amastatin 26258:J-113,397 26219:TH-030418 26189:Ro65-6570 26184:Ro64-6198 26111:Etorphine 26019:Zyklophin 26009:Taxifolin 25899:LY-255582 25859:Cyclofoxy 25809:Axelopran 25723:Xorphanol 25713:U-54,494A 25681:Tifluadom 25671:TH-030418 25601:Oxycodone 25591:Oripavine 25561:Naltriben 25546:Nalmefene 25501:Mianserin 25471:Lufuradom 25376:GR-103545 25351:Etorphine 25331:Enadoline 25231:Butorphan 25226:BRL-52537 25191:Apadoline 25100:Taxifolin 25095:SoRI-9409 25055:Naltriben 25040:Nalmefene 25015:LY-255582 24945:Axelopran 24884:Xorphanol 24854:TH-030418 24834:SB-235863 24794:Oxycodone 24789:Oripavine 24654:Etorphine 24544:Butorphan 24509:Amoxapine 24448:Taxifolin 24373:Naloxegol 24348:Nalmefene 24318:LY-255582 24248:Cyprodime 24243:Cyclofoxy 24210:Axelopran 24190:Alvimopan 24185:Akuammine 24170:α-Gliadin 24109:Xorphanol 24099:Valorphin 24044:TH-030418 23902:Oxycodone 23897:Oripavine 23832:Nalmexone 23787:Methadone 23767:LS-115509 23647:Etorphine 23637:Eseroline 23482:Butorphan 23343:full list 23248:See also: 23223:SoRI-9804 23171:Reserpine 23141:GBR-12935 23136:Efavirenz 23056:Roxindole 23034:methadone 23021:N-Me-5-HT 22991:Efavirenz 22949:3-MeO-PCP 22892:Amoxapine 22760:Pridefine 22730:Naphyrone 22594:Tofenacin 22513:Trazodone 22503:SB-649915 22498:Quipazine 22493:LY-393558 22418:Ifoxetine 22413:Indalpine 22289:methadone 22178:Mianserin 22168:Amoxapine 22036:Pridefine 22006:Naphyrone 21870:Tofenacin 21820:CP-39,332 21739:Fencamine 21734:Bupropion 21703:Tandamine 21698:Talsupram 21658:Daledalin 21556:Rimcazole 21546:Pridefine 21511:Modafinil 21436:Fluorenol 21406:Efavirenz 21339:Bupropion 21299:Adrafinil 21263:Tropoxane 21153:Altropane 21150:Tropanes: 21127:Naphyrone 21091:Pipradrol 21010:GBR-13098 21005:GBR-13069 21000:GBR-12935 20995:GBR-12783 20889:See also: 20869:Unsorted: 20812:MDL-27266 20792:FR-115427 20787:FPL-12495 20744:ARR-15896 20672:Halothane 20662:Enflurane 20620:Magnesium 20571:Ro 8-4304 20546:Eliprodil 20457:PD-137889 20417:Morphanol 20392:Methadone 20387:Memantine 20337:Ibogamine 20312:Etoxadrol 20242:ARL-16247 20232:ARL-12495 20217:Aptiganel 20182:4-MeO-PCP 20177:3-MeO-PCP 20167:3-MeO-PCE 20130:Co 101676 20103:MRZ 2/576 20053:GV-196771 20043:Felbamate 20020:CGP-39653 20000:ACEA-1328 19995:ACEA-1011 19938:NPC-17742 19933:NPC-12626 19918:LY-274614 19913:LY-235959 19908:LY-233053 19893:CGS-19755 19888:CGP-40116 19883:CGP-39653 19878:CGP-39551 19873:CGP-37849 19863:AP5 (APV) 19764:Sarcosine 19640:β-Fluoro- 19589:Glutamate 19584:Aspartate 19573:Agonists: 19530:Enflurane 19474:LY-382884 19434:ACEA-1011 19419:Halothane 19414:Enflurane 19409:Diazoxide 19382:LY-339434 19367:Glutamate 19331:Agonists: 19276:Irampanel 19271:Halothane 19246:Enflurane 19120:ACEA-1011 19095:Piracetam 19075:ORG-26576 19070:Nooglutyl 19060:LY-503430 19055:LY-451646 19050:LY-404187 19045:LY-395153 19040:LY-392098 19025:Diazoxide 18953:Glutamate 18922:Agonists: 18850:See also: 18749:Mepacrine 18695:Ivacaftor 18611:Carbachol 18494:Ibuprofen 18484:Amiloride 18443:Solnatide 18415:Amiloride 18344:Aconitine 18306:Evenamide 18281:Saxitoxin 18196:Risocaine 18146:Lidocaine 18091:Butacaine 18067:Articaine 17994:Phenytoin 17904:Tocainide 17899:Sparteine 17894:Quinidine 17854:Lorajmine 17849:Lidocaine 17839:Encainide 17824:Aprindine 17565:Sarakalim 17555:Pinacidil 17545:Naminidil 17535:Minoxidil 17530:Mazokalim 17515:Diazoxide 17505:Bimakalim 17500:Aprikalim 17463:Tertiapin 17443:Clozapine 17360:Glipizide 17155:Quinidine 17105:Ergtoxins 17070:Cisapride 17060:BRL-32872 17040:Azimilide 17003:(KCNH2, K 16978:Tedisamil 16963:Quinidine 16953:Paxilline 16918:Inakalant 16913:Ibutilide 16898:Hanatoxin 16853:Bunaftine 16848:Bretylium 16843:Azimilide 16828:Adekalant 16787:Potassium 16769:Bay K8644 16710:Sesamodil 16660:Monatepil 16650:Manoalide 16645:Magnesium 16630:Imepitoin 16620:Fendiline 16600:Ethadione 16590:Eperisone 16570:Dauricine 16545:Berbamine 16456:δ subunit 16260:PD-173212 16175:Verapamil 16165:Ronipamil 16155:Nexopamil 16140:Falipamil 16135:Etripamil 16120:Devapamil 16115:Dagapamil 16095:Nictiazem 16085:Diltiazem 16075:Diltiazem 16025:Oxodipine 15713:See also: 15694:Yohimbine 15674:Terguride 15639:Sarizotan 15584:L-745,870 15579:L-741,626 15534:Buspirone 15488:Opipramol 15478:Amoxapine 15271:Molindone 15266:Melperone 15211:Clozapine 15171:Asenapine 15090:Sulpiride 15070:Promazine 15060:Preclamol 14975:Lenperone 14850:Azaperone 14790:Roxindole 14780:Ro10-5824 14755:Pukateine 14745:Preclamol 14735:Piribedil 14695:Modafinil 14635:Aplindore 14630:Adrafinil 14528:-Tyrosine 14504:Ibopamine 14447:Terguride 14442:Pergolide 14393:Ergolines 14376:8-OH-PBZI 14371:7-OH-DPAT 14366:5-OH-DPAT 14350:Memantine 14308:SCH-23390 14303:Perlapine 14278:Berupipam 14197:Clozapine 14182:Asenapine 14081:Mevidalen 14046:Tavapadon 13975:-Tyrosine 13946:Ibopamine 13874:Terguride 13869:Pergolide 13840:Ergolines 13485:Pentamine 13480:Pempidine 13430:Methadone 13425:Memantine 13345:Halothane 13335:Gallamine 13315:Enflurane 13270:Diadonium 13185:Bupropion 12970:SIB-1553A 12965:SIB-1508Y 12955:SB-206553 12780:Carbachol 12760:AR-R17779 12750:Anatabine 12745:Anabasine 12710:A-867,744 12705:A-582,941 12700:A-366,833 12413:Tropacine 12331:cidoxepin 12301:Tofenacin 12271:mianserin 12263:amoxapine 12185:RU-47,213 12165:Quinidine 12125:Pizotifen 12085:Pethidine 11950:Mazaticol 11930:J-104,129 11895:Himbacine 11852:Flavoxate 11797:Drofenine 11672:Camylofin 11662:Biperiden 11637:Benzilone 11593:clozapine 11574:AQ-RA 741 11544:perlapine 11536:meclizine 11496:buclizine 11483:Anisodine 11468:AF-DX 384 11463:AF-DX 250 11310:Muscarine 11285:L-689,660 11275:Itameline 11260:Clozapine 11215:Carbachol 11200:Arecoline 10339:Turner DM 9867:6 January 9477:BE 634208 8973:206519749 8656:221497233 7790:: 72–79. 7682:CNS Drugs 7098:Addiction 6873:214643776 6651:CiteSeerX 6546:CNS Drugs 6395:: 52–69. 6373:198965307 6351:(9): 62. 6111:208035394 5915:CNS Drugs 5096:221236545 4780:Drugs.com 4580:18 August 4435:223557698 4356:Addiction 4336:212418003 4135:257117630 4109:2769-2795 3543:24 August 3300:Drugs.com 3167:date rape 3040:Australia 2966:Detection 2936:free base 2888:-ketamine 2873:-ketamine 2855:Structure 2812:Synthesis 2807:Chemistry 2721:ketamine 2662:secretion 2659:prolactin 2537:-(+) and 2485:Inhibitor 2456:Inhibitor 2427:Inhibitor 1938:0.25–0.66 1836:glutamate 1764:memantine 1699:Clonidine 1683:midazolam 1673:Ketamine 1658:tolerance 1489:dysphoria 1459:Pregnancy 1454:cirrhosis 1448:psychosis 1177:. A 2011 933:Chirality 801:ChEMBL742 628:1867-66-9 602:6740-88-1 541:Excretion 503:half-life 429:intestine 210:analgesic 181:Routes of 171:liability 169:Addiction 143:Pregnancy 88:Monograph 82:Drugs.com 38851:Medicine 38777:ketamine 38737:nicotine 38665:receptor 38619:levodopa 38609:cannabis 38597:agonists 38594:receptor 38571:phenibut 38555:blockers 38518:morphine 38510:agonists 38496:euphoria 38429:Glaucine 38380:U-69,593 38305:Morphine 38270:Ibogaine 38197:agonists 38131:Kerosene 38126:Gasoline 38085:Zolpidem 38080:Zaleplon 38068:Muscimol 38028:levodopa 37940:Lisuride 37912:agonists 37873:THJ-2201 37768:Nabilone 37738:MAM-2201 37703:JTE 7-31 37698:FUBIMINA 37663:EAM-2201 37538:5F-PB-22 36727:WIN-2299 36582:CS-27349 36492:Atropine 36453:Selfotel 36408:Ibogaine 36378:Budipine 36145:3-HO-PCP 36140:3-HO-PCE 36089:Ketamine 35970:Glaucine 35860:4-HO-EPT 35855:4-HO-DBT 35745:ME-18-MC 35735:Ibogaine 35601:5-MeO-4, 35588:5-MeO-2, 35233:2CD-5EtO 35101:Escaline 34497:25I-NBBr 34492:25I-NBAm 34457:25C-NBCl 34303:25P-NBOH 34298:25I-NBOH 34293:25H-NBOH 34288:25F-NBOH 34283:25E-NBOH 34278:25D-NBOH 34268:25C-NBOH 34263:25B-NBOH 34225:25P-NBMD 34220:25I-NBMD 34215:25H-NBMD 34210:25F-NBMD 34205:25E-NBMD 34200:25D-NBMD 34195:25C-NBMD 34190:25B-NBMD 34162:25T7-NBF 34157:25T2-NBF 33332:2C-B-FLY 33208:drug use 33121:Overdose 33057:drug use 32983:Thailand 32968:Suriname 32948:Slovakia 32923:Portugal 32908:Paraguay 32868:Malaysia 32808:Honduras 32758:Colombia 32743:Cambodia 32464:Virginia 32454:Maryland 32449:Colorado 32404:Slovakia 32399:Portugal 32072:Smokeasy 31966:Wine bar 31868:Teahouse 31591:Hash oil 31522:Atropine 31480:Muscimol 31470:Ketamine 31433:Glaucine 31398:Psilocin 31212:Nicotine 31119:Caffeine 31079:Tramadol 31055:Morphine 31032:Dilaudid 31008:Fentanyl 30999:Darvocet 30989:Krokodil 30964:Suboxone 30903:Gasoline 30893:solvents 30876:Medical 30651:GABAkine 30329:Benmoxin 30285:Tiazesim 30009:Ketamine 29994:Gepirone 29553:Ketamine 29432:Funapide 29427:DSP-2230 29287:Nabilone 29282:Cannabis 29186:Ampyrone 28958:Tolmetin 28953:Sulindac 28930:Etodolac 28908:Acetates 28879:Isoxicam 28853:Suprofen 28843:Naproxen 28717:+codeine 28652:Tramadol 28647:Tilidine 28627:Propiram 28542:Fentanyl 28522:Dezocine 28471:Thebacon 28443:+aspirin 28386:+aspirin 28284:Laudanum 28269:Morphine 28257:+aspirin 28072:Ketamine 28028:Fentanyl 28008:Morphine 27980:Diazepam 27909:Propofol 27899:Ciprofol 27822:Ethylene 27654:Pimozide 27609:Dezocine 27499:Naloxone 27459:Metaphit 27454:Fourphit 27434:Unsorted 27370:Ibogaine 27310:SAS-0132 27260:UKH-1114 27217:Ketamine 27202:DKR-1051 27197:DKR-1005 27078:Ibogaine 26710:L-687384 26705:Ketamine 26298:Trap-101 26288:SR-16430 26209:SR-16435 26063:(PheΨ(CH 26043:Agonists 25954:Naloxone 25864:Dezocine 25834:Catechin 25789:Apigenin 25718:U-69,593 25511:Morphine 25481:MB-1C-OH 25421:Ketamine 25406:Ibogaine 25371:GR-89696 25361:Fentanyl 25241:BW373U86 25129:Agonists 25119:κ-opioid 25065:Naloxone 24960:Catechin 24935:Apigenin 24874:Tramadol 24859:Thebaine 24769:Morphine 24689:Ibogaine 24659:Fentanyl 24639:DPI-3290 24609:Dezocine 24554:BW373U86 24534:Biphalin 24499:ADL-5859 24472:Agonists 24462:δ-opioid 24388:Naloxone 24313:Lobeline 24298:Ibogaine 24220:Catechin 24200:Apigenin 24069:Tramadol 24064:Tilidine 24049:Thebaine 24019:SC-17599 23989:Propiram 23949:Pericine 23892:OM-3-MNZ 23817:Morphine 23707:Ketamine 23652:Fentanyl 23562:Dezocine 23497:BW373U86 23467:Biphalin 23352:3-HO-PCP 23338:Agonists 23328:μ-opioid 23210:Luteolin 23161:Lobeline 23151:Ibogaine 23050:tramadol 22996:Hypidone 22957:ketamine 22935:loxapine 22795:Tropanes 22725:Mazindol 22715:JZ-IV-10 22549:CP-39332 22508:TGBA01AD 22301:tramadol 22244:ketamine 22230:loxapine 22071:Tropanes 22001:Mazindol 21991:JZ-IV-10 21693:Talopram 21678:Mazindol 21643:Amedalin 21501:Metaphit 21496:Mesocarb 21486:Mazindol 21456:Ketamine 21258:Troparil 21015:JJC8-088 20817:Metaphit 20727:Urethane 20615:Hydrogen 20612:Cations: 20522:Tramadol 20347:Ketamine 20332:Ibogaine 20247:Budipine 20162:3-HO-PCP 20088:LU-73068 20078:L-701324 20073:L-689560 19980:5,7-DCKA 19968:Selfotel 19850:SAGE-718 19845:SAGE-301 19840:SAGE-201 19781:Spermine 19771:Neomycin 19736:-Alanine 19728:L-687414 19687:-Alanine 19644:-alanine 19633:Theanine 19499:Theanine 19397:SYM-2081 19205:Theanine 18835:instead. 18810:instead. 18721:Blockers 18713:Unsorted 18639:Blockers 18540:Blockers 18517:Chloride 18479:A-317567 18471:Blockers 18420:Benzamil 18407:Blockers 18236:NKTR-171 18231:GDC-0276 18226:Funapide 18221:DSP-2230 18216:AZD-3161 18181:Procaine 18096:Butamben 17944:Ethotoin 17819:Ajmaline 17798:Blockers 17757:Riluzole 17716:Blockers 17614:Blockers 17520:Emakalim 17298:Blockers 17140:Pimozide 17010:Ajmaline 16810:Blockers 16625:Fostedil 16555:Canadine 16525:Phenibut 16485:Baclofen 16434:NP078585 16379:Bepridil 16217:SR-33805 16170:Tiapamil 16130:Emopamil 16110:Anipamil 15845:Blockers 15684:Tiapride 15594:LEK-8829 15519:Azapride 15437:Itopride 15371:Zotepine 15050:Pimozide 15025:Perazine 15000:Moperone 14990:Loxapine 14700:OSU-6162 14685:Ketamine 14615:A-412997 14463:Ciladopa 14458:2-OH-NPA 14432:Lisuride 14334:Agonists 14298:Odapipam 14283:Ecopipam 14267:Zotepine 14131:Loxapine 13864:Lisuride 13859:LEK-8829 13828:Trepipam 13793:6-Br-APB 13782:Agonists 13697:See also 13639:lecithin 13615:prodrugs 13565:Tramadol 13415:ME-18-MC 13380:Ketamine 13370:Ibogaine 13190:BW284C51 12945:RJR-2429 12935:Pyrantel 12895:Nicotine 12890:Morantel 12880:Lobeline 12845:EVP-6124 12840:EVP-4473 12795:Cytisine 12790:Cotinine 12695:A-84,543 12666:Agonists 12585:See also 12527:lecithin 12503:prodrugs 12473:WIN-2299 12449:loxapine 12135:Pridinol 11995:Metixene 11752:DAU-5884 11732:CS-27349 11652:Bevonium 11621:zotepine 11609:rilapine 11579:Atropine 11240:CDD-0102 11235:CDD-0098 11230:CDD-0097 11225:CDD-0078 11220:CDD-0034 11195:AQRA-741 11180:AF150(S) 11142:Agonists 11030:11246501 10929:Archived 10871:18954680 10836:25572412 10828:15363764 10819:10822209 10779:33081837 10728:20724638 10671:29718013 10622:Archived 10592:Archived 10527:Archived 10495:Archived 10476:Archived 10445:Archived 10411:Archived 10341:(1994). 10323:, ibid. 10311:(2000). 10288:(1978). 10269:, ibid. 10220:(1997). 10218:Lilly JC 10168:11304647 10130:Archived 10093:2 August 10087:Archived 10051:archived 10012:Archived 9985:2 August 9979:Archived 9951:2 August 9945:Archived 9931:2 August 9861:Archived 9816:45232796 9808:27960559 9771:19 March 9765:Archived 9742:43438286 9734:10686270 9691:Archived 9666:27965560 9615:29516392 9420:25702819 9371:Archived 9258:27596215 9165:23776189 9157:17591653 9119:11282259 9016:17758902 9008:19391150 8965:18720422 8930:39039021 8922:26302763 8883:35626369 8875:28097909 8837:26075331 8698:28418641 8648:32882205 8613:19158287 8564:18815045 8515:30159489 8463:29621538 8414:23651917 8406:10754635 8354:25643394 8346:12456425 8305:16730695 8266:27469513 8208:12232776 8164:24494428 8156:21911285 8121:20358363 8064:14530949 7985:23527166 7945:PLOS ONE 7916:28829612 7859:27425886 7814:26519901 7761:29668918 7712:29516301 7655:29446381 7612:29879390 7571:29532791 7505:Archived 7487:23183107 7435:29501913 7375:27028535 7337:28858450 7293:10773503 7257:16395307 7216:12246068 7167:24005549 7118:19919593 7083:24982568 7034:27330331 6983:28966667 6926:Archived 6922:25034266 6914:21155941 6865:32212278 6823:21102971 6782:31791675 6733:Archived 6729:19091264 6673:21036393 6628:23152273 6574:52302073 6566:30232735 6523:Archived 6519:30387431 6478:33923061 6427:73432875 6419:30711788 6365:31352520 6297:Archived 6279:34623633 6227:34510411 6167:Archived 6141:Archived 6115:Archived 6103:31729893 6056:Archived 6052:28186580 6044:28395988 5992:31975918 5943:13679905 5935:29736744 5893:28320520 5885:28249076 5845:25925720 5837:15621365 5802:31888509 5751:21412369 5710:26495312 5659:30019434 5591:24658476 5583:25716117 5542:29870457 5488:24082612 5437:35989801 5302:11585502 5259:10 April 5230:27536846 5222:28731926 5187:25886322 5131:25064742 5088:32826629 5046:11750186 5000:10711913 4954:31435021 4946:24993063 4911:36323023 4868:Archived 4864:17301376 4825:Archived 4821:29262083 4785:Archived 4749:(2021). 4733:20693870 4685:29870458 4617:27028535 4574:Archived 4570:31082131 4543:33162856 4491:33174760 4427:33065824 4384:11064759 4376:21777321 4328:32133835 4287:54628949 4279:30513009 4241:21256625 4195:29945898 4127:37786516 4118:10528797 4020:41380105 4012:27763887 3970:15787750 3962:12065445 3927:30723730 3871:Archived 3867:21419322 3811:18175098 3709:31215725 3645:23521979 3579:Archived 3537:Archived 3514:Archived 3454:28339431 3416:Archived 3412:28657160 3353:Ketamine 3330:Archived 3304:Archived 3282:Archived 3173:Research 3155:suicides 2756:. It is 2727:epidural 2674:striatal 2666:increase 2509:Agonist 1679:propofol 1654:bingeing 1625:cachexia 1597:tramadol 1542:cystitis 1509:propofol 1425:such as 1385:Seizures 1322:Spravato 1242:morphine 1183:sedative 1168:propofol 1160:propofol 1067:sedation 1036:Ketamine 1026:(verify) 684:DrugBank 431:(oral): 402:: 16–20% 400:By mouth 396:: 25–30% 390:: 24–30% 384:: 45–50% 376:Epidural 279:Class C1 221:ATC code 158: B3 145:category 132:Ketamine 115:Ketamine 110:DailyMed 30:Ketamine 38917:Ketones 38801:(e.g., 38771:(e.g., 38763:poppers 38757:(e.g., 38741:tobacco 38735:(e.g., 38721:(e.g., 38670:(e.g., 38651:cocaine 38649:(e.g., 38627:(e.g., 38617:(e.g., 38582:(e.g., 38514:opioids 38375:U-50488 38148:Toluene 38136:Propane 38104:(Mixed 38022:), and 38004:cocaine 37868:THJ-018 37853:STS-135 37848:SDB-006 37843:SDB-005 37778:NM-2201 37773:Nabitan 37708:JTE-907 37678:FUB-144 37668:FAB-144 37628:APINACA 37533:5F-NNE1 37470:JWH-424 37465:JWH-398 37460:JWH-387 37455:JWH-359 37450:JWH-350 37445:JWH-336 37440:JWH-307 37435:JWH-302 37430:JWH-300 37425:JWH-258 37420:JWH-253 37415:JWH-251 37410:JWH-250 37405:JWH-249 37400:JWH-234 37395:JWH-229 37390:JWH-220 37385:JWH-213 37380:JWH-210 37375:JWH-210 37370:JWH-205 37365:JWH-203 37360:JWH-200 37355:JWH-199 37350:JWH-198 37345:JWH-197 37340:JWH-196 37335:JWH-195 37330:JWH-194 37325:JWH-193 37320:JWH-192 37315:JWH-185 37310:JWH-184 37305:JWH-182 37300:JWH-181 37295:JWH-176 37290:JWH-175 37285:JWH-171 37280:JWH-167 37275:JWH-166 37270:JWH-164 37265:JWH-161 37260:JWH-149 37255:JWH-149 37250:JWH-148 37245:JWH-147 37240:JWH-139 37235:JWH-133 37230:JWH-122 37225:JWH-120 37220:JWH-116 37215:JWH-098 37210:JWH-081 37205:JWH-073 37200:JWH-057 37195:JWH-051 37190:JWH-048 37185:JWH-047 37180:JWH-030 37175:JWH-019 37170:JWH-018 37165:JWH-015 37160:JWH-007 37032:AM-6545 37027:AM-4113 37022:AM-4056 37017:AM-4054 37012:AM-4030 37007:AM-3102 37002:AM-2389 36997:AM-2233 36992:AM-2232 36987:AM-2213 36982:AM-2212 36977:AM-2201 36972:AM-1902 36967:AM-1714 36962:AM-1710 36957:AM-1248 36952:AM-1241 36947:AM-1235 36942:AM-1221 36937:AM-1220 36932:AM-1172 36927:AM-1116 36764:Natural 36637:EA-3834 36632:EA-3580 36627:EA-3443 36622:EA-3167 36368:8A-PDHQ 36241:PRE-084 35980:M-ALPHA 35345:2C-B-PP 35303:Ganesha 35293:DOB-FLY 35273:βk-2C-I 35268:βk-2C-B 35228:2CB-Ind 35025:MMDA-3a 34985:DMMDA-2 34577:ZDCM-04 34152:25P-NBF 34147:25I-NBF 34142:25H-NBF 34137:25E-NBF 34132:25D-NBF 34127:25C-NBF 34122:25B-NBF 33879:2C-T-33 33874:2C-T-32 33869:2C-T-31 33864:2C-T-30 33859:2C-T-28 33854:2C-T-27 33849:2C-T-25 33844:2C-T-24 33839:2C-T-23 33829:2C-T-22 33824:2C-T-21 33819:2C-T-20 33814:2C-T-19 33809:2C-T-18 33804:2C-T-17 33799:2C-T-16 33794:2C-T-15 33789:2C-T-14 33784:2C-T-13 33779:2C-T-12 33774:2C-T-11 33769:2C-T-10 33584:2C-B-AN 33547:PRO-LAD 33512:LSM-775 33502:LSD-Pip 33487:LPD-824 33467:ETH-LAD 33392:1cP-LSD 33377:Lyserg‐ 32883:Nigeria 32878:Moldova 32798:Germany 32793:Finland 32788:Estonia 32728:Bolivia 32384:Germany 32183:Whoonga 32034:Therapy 31702:Poppers 31680:Ecstasy 31665:Cocaine 31613:APINACA 31603:JWH-018 31586:Hashish 31458:poppers 31294:Ecstasy 31227:Tobacco 31175:Ephedra 31153:Cocaine 30973:Codeine 30967:Subutex 30952:Opioids 30583:Lithium 30151:Doxepin 29683:and/or 29558:Menthol 29533:Camphor 29410:(e.g., 29403:Nefopam 29388:cocaine 29386:(e.g., 29135:Salicin 28872:Oxicams 28697:Bucetin 28669:Viminol 28407:Metopon 28252:Codeine 28240:Opiates 28231:Opioids 28000:Opioids 27891:Phenols 27524:UMB-116 27519:UMB-103 27514:UMB-101 27509:UMB-100 27300:MIN-101 27290:CT-1812 27280:BD-1067 27275:BD-1008 27182:BD-1047 27118:Saffron 27103:RHL-033 26873:Dup-734 26858:BD-1067 26853:BD-1063 26848:BD-1060 26843:BD-1047 26838:BD-1031 26833:BD-1008 26778:PRE-084 26595:Cocaine 26560:BD-1052 26454:Others: 26382:RB-3007 26334:BL-2401 26303:UFP-101 26268:NalBzOH 26263:JTC-801 26204:SR-8993 26141:MT-7716 26091:BU08070 25944:MR-2266 25924:MeJDTic 25854:CVL-354 25824:BU09059 25814:AZ-MTAB 25794:Arodyne 25754:6'-GNTI 25749:5'-GNTI 25708:U-50488 25688:(e.g., 25536:NalBzOH 25521:MR-2034 25486:Menthol 25476:Matrine 25211:BAM-22P 25206:BAM-18P 25201:BAM-12P 25141:6'-GNTI 24910:5'-NTII 24844:SNC-162 24784:NalBzOH 24704:KNT-127 24634:DPI-221 24569:Codeine 24529:BAM-18P 24519:AZD2327 24484:6'-GNTI 24378:Naloxol 24104:Viminol 24094:U-47700 24079:TRIMU 5 23984:Prodine 23927:OxyPNPH 23842:Neopine 23827:NalBzOH 23797:Metopon 23772:Matrine 23522:Codeine 23472:BU08070 23447:BAM-22P 23442:BAM-18P 23437:BAM-12P 23402:AH-7921 23146:GZ-793A 23090:(e.g., 23028:(e.g., 23026:Opioids 22947:(e.g., 22933:(e.g., 22899:(e.g., 22887:A-80426 22884:Others: 22846:Doxepin 22799:cocaine 22797:(e.g., 22745:NS-2359 22740:Nefopam 22695:HDMP-28 22685:EXP-561 22645:Cocaine 22574:McN5652 22453:RTI-353 22283:(e.g., 22281:Opioids 22242:(e.g., 22228:(e.g., 22206:(e.g., 22201:Others: 22122:Doxepin 22075:cocaine 22073:(e.g., 22021:NS-2359 22016:Nefopam 21971:HDMP-28 21961:EXP-561 21921:Cocaine 21845:McN5652 21764:LR-5182 21526:NS-2359 21516:Nefopam 21476:LR-5182 21421:EXP-561 21296:Others: 21248:RTI-336 21243:RTI-229 21238:RTI-177 21233:RTI-150 21228:RTI-126 21223:RTI-121 21218:RTI-113 21213:RTI-112 21173:Cocaine 21071:HDMP-28 20990:DBL-583 20861:saffron 20707:Toluene 20697:Octanol 20677:Hexanol 20632:Benzene 20608:TCN-213 20603:TCN-201 20598:MPX-007 20593:MPX-004 20187:8A-PDHQ 20125:Arcaine 20118:ZD-9379 19815:sulfate 19744:-Serine 19718:Glycine 19703:-Serine 19618:Proline 19545:NS-3763 19518:(e.g., 19509:UBP-302 19387:Proline 19229:(e.g., 19105:S-18986 19035:IDRA-21 19020:CX-1942 19015:CX-1739 18963:Proline 18489:Aspirin 18311:Menthol 18298:Others: 18268:Toxins: 18111:Cocaine 17636:GAL-021 17256:KCNQ (K 17218:KCNQ (K 17035:AZD1305 16973:Sotalol 16968:ShK-186 16948:Notoxin 16635:JTV-519 16615:Fasudil 16344:ProTx I 16324:ABT-639 16311:SNX-482 16182:AH-1058 16179:Others: 15822:Calcium 15549:F-15063 15387:AS-8112 15176:BL-1020 15005:Naranol 14775:RDS-127 14625:ABT-724 14620:ABT-670 14589:F-15063 14538:XP21279 13991:A-68930 13980:XP21279 13926:BCO-001 13890:A-86929 13885:A-77636 13635:Choline 13195:BW-A444 13173:(e.g., 13166:BNC-210 13154:(e.g., 13117:ABT-126 13101:(e.g., 13060:XY-4083 13025:TC-6683 13020:TC-5619 13015:TC-5214 13010:TC-2216 13005:TC-1827 13000:TC-1734 12995:TC-1698 12905:NS-1738 12899:tobacco 12785:Choline 12730:ABT-894 12725:ABT-560 12720:ABT-418 12715:ABT-202 12523:Choline 12435:(e.g., 12355:doxepin 12313:(e.g., 12261:(e.g., 12237:(e.g., 12130:Poldine 12090:pFHHSiD 12015:Nefopam 11817:EA-3834 11812:EA-3580 11807:EA-3443 11802:EA-3167 11657:BIBN 99 11591:(e.g., 11490:(e.g., 11315:NGX-267 11295:McNA343 11250:Choline 10991:7212404 10898:4604091 10770:7574484 10719:3116441 10698:Bibcode 10690:Science 10567:27 July 10321:254–258 10286:Moore M 10026:Baker N 9917:Part II 9697:27 July 9657:5126726 9640:: 612. 9607:5325977 9511:9707751 9411:4541975 9340:7248132 9299:3970799 9250:7198883 9078:8122957 8988:Synapse 8945:Synapse 8828:4556466 8788:2164198 8780:9105235 8739:8942324 8604:2744993 8555:2605271 8507:9523822 8454:5960634 8257:5034706 8112:2869248 8072:9322174 8029:9915326 7976:3602154 7953:Bibcode 7937:Roth BL 7907:5641405 7805:4763983 7752:6070027 7703:6005380 7663:3334820 7635:Bibcode 7562:5999402 7478:3534778 7426:6211562 7383:5078489 7208:8267198 7159:7879932 7074:4059572 7025:4898409 6974:5615221 6773:8457026 6681:5667719 6619:6483733 6469:8146518 6303:29 July 6270:8499740 6218:8434915 6173:29 July 6147:20 July 5983:6493090 5793:6937868 5701:4606413 5533:6023582 5479:3777369 5428:9389002 5386:1139377 5345:1324453 5337:1763596 5178:4258981 4903:9451493 4831:5 March 4676:6023575 4625:5078489 4534:7587874 4482:7918868 4186:6020109 3919:4603048 3877:28 July 3747:6884418 3700:6851782 3636:6493613 3403:6481583 3226:rodents 3214:rabbits 3163:amnesia 3071:In the 3064:of the 2975:History 2837:decalin 2825:bromine 2797:tritium 2670:Imaging 2609:(MAOI) 2533:. The 2110:Agonist 2046:Agonist 1920:Species 1907:Value ( 1882:(eEF2) 1878:of the 1850:in the 1558:dysuria 1463:Active 1421:Severe 1164:Ketofol 1108:in the 1071:amnesia 1050:and in 868:Formula 693:DB01221 639:PubChem 434:Major: 315:Class B 300:: 289:: 237:) 231: ( 229:N01AX03 130::  112::  38837:Portal 38712:) and 38538:kratom 38522:heroin 38422:Others 38295:LPK-26 38260:Heroin 38205:2-EMSB 38155:Ethers 38121:Butane 38053:CI-966 37888:XLR-11 37878:UR-144 37823:QUCHIC 37743:MDA-19 37608:ADBICA 37563:AB-005 37558:AB-001 37518:5F-AMB 37503:5F-ADB 37139:HU-345 37134:HU-336 37129:HU-331 37124:HU-320 37119:HU-308 37114:HU-243 37109:HU-239 37104:HU-211 37099:HU-210 36922:AM-938 36917:AM-926 36912:AM-919 36907:AM-906 36902:AM-905 36897:AM-883 36892:AM-881 36887:AM-855 36882:AM-735 36877:AM-694 36872:AM-679 36867:AM-678 36862:AM-661 36857:AM-630 36852:AM-411 36847:AM-404 36842:AM-381 36837:AM-374 36832:AM-356 36827:AM-281 36822:AM-279 36817:AM-251 36812:AM-087 36736:Others 36657:JB-336 36652:JB-318 36612:Ditran 36358:2-EMSB 36351:Others 36224:Others 36210:(PCPy) 36187:(PCDE) 35999:5-MAPB 35943:Others 35848:Others 35720:18-MAC 35288:DMBMPP 35278:DESOXY 35243:5-TOET 35238:2-TOET 35196:Others 35020:MMDA-2 34959:HOT-17 34849:4C-T-2 34790:3C-MAL 34780:3C-DFE 34036:NB4OMe 33958:NB3OMe 33943:25C-NB 33938:25B-NB 33889:2C-TFM 33884:2C-TFE 33764:2C-T-9 33759:2C-T-8 33754:2C-T-7 33749:2C-T-6 33744:2C-T-5 33739:2C-T-4 33734:2C-T-3 33729:2C-T-2 33704:2C-O-4 33694:2C-NH2 33669:2C-G-N 33664:2C-G-6 33659:2C-G-5 33654:2C-G-4 33649:2C-G-3 33644:2C-G-2 33639:2C-G-1 33559:amines 33537:MLD-41 33477:LAE-32 33472:IP-LAD 33442:BU-LAD 33437:ALD-52 33432:AL-LAD 33417:1V-LSD 33402:1P-LSD 33387:1B-LSD 33379:amides 33367:TFMFly 32988:Turkey 32978:Taiwan 32933:Russia 32918:Poland 32898:Panama 32888:Norway 32863:Latvia 32843:Kosovo 32773:Cyprus 32733:Brazil 32723:Bhutan 32713:Belize 32459:Oregon 32414:Sweden 32374:Canada 32133:Hippie 32067:Loosie 31536:Datura 31382:Peyote 31367:LSD-25 31124:Coffee 31048:Kratom 31017:Heroin 31002:Darvon 30919:Other 30708:WHO-EM 30421:Mixed: 30278:Others 29962:Others 29870:NaSSAs 29597:WHO-EM 29511:Others 29223:Others 29209:  29158:  28984:  28938:  28828:  28815:  28807:  28774:NSAIDs 28655:  28435:  28374:  28346:  28318:  28149:WHO-EM 28119:Others 27539:YZ-185 27534:YZ-069 27529:YZ-011 27420:UMB-82 27415:UMB-23 27295:LR-172 27285:CM-156 27270:AC-927 27187:BD1063 27148:YKP10A 27113:RTI-55 27000:4-IPBS 26990:4C-T-2 26908:NE-100 26903:MS-377 26898:LR-172 26893:LR-132 26878:E-5842 26868:CM-156 26828:AC-927 26813:UMB-82 26808:UMB-23 26555:BD-737 26530:4-PPBP 26392:Selank 26377:RB-120 26372:RB-101 26316:Others 26243:AT-076 26136:MCOPPB 25799:AT-076 25645:salvia 25526:N-MPPP 25466:LPK-26 25090:SDM25N 24940:AT-076 24879:TRV250 24839:SNC-80 24709:Kratom 24489:7-SIOM 24205:AT-076 24195:AM-251 24084:TRV734 23979:PL-017 23717:Kratom 23702:IBNtxA 23200:Others 22755:PRC200 22700:HP-505 22443:PIM-35 22031:PRC200 21976:HP-505 21784:O-2172 21531:O-2172 21208:RTI-55 20737:Xylene 20637:Butane 20010:AV-101 19723:HA-966 19010:CX-717 19000:CX-614 18995:CX-546 18990:CX-516 18786:Others 17775:Sodium 17428:Barium 17232:XE-991 17100:E-4031 17050:BeKm-1 17020:AmmTX3 16903:HgeTx1 16893:E-4031 16675:Osthol 16444:TROX-1 16329:ML-218 15689:UH-232 15669:SV-293 15505:Others 14655:BP-897 14606:Others 14386:UH-232 14274:Others 13987:Others 13225:Curare 13142:AQW051 13089:18-MAC 13045:UB-165 12855:GTS-21 12685:5-HIAA 12653:nAChRs 11792:Ditran 11443:4-DAMP 11420:YM-796 11185:AF267B 11129:mAChRs 11028:  10989:  10921:  10896:  10869:  10834:  10826:  10816:  10777:  10767:  10726:  10716:  10669:  10501:7 June 10482:7 June 10451:7 June 10417:18 May 10376:  10349:  10327:  10296:  10273:  10238:  10197:  10166:  9838:  9814:  9806:  9740:  9732:  9664:  9654:  9613:  9605:  9509:  9483:  9470:  9418:  9408:  9363:  9338:  9297:  9256:  9248:  9209:526385 9207:  9163:  9155:  9117:  9076:  9038:  9014:  9006:  8971:  8963:  8928:  8920:  8881:  8873:  8835:  8825:  8786:  8778:  8737:  8696:  8654:  8646:  8611:  8601:  8562:  8552:  8513:  8505:  8461:  8451:  8412:  8404:  8352:  8344:  8303:  8264:  8254:  8206:  8162:  8154:  8119:  8109:  8070:  8062:  8027:  7983:  7973:  7914:  7904:  7867:644350 7865:  7857:  7812:  7802:  7759:  7749:  7710:  7700:  7661:  7653:  7627:Nature 7610:  7590:Neuron 7569:  7559:  7485:  7475:  7433:  7423:  7381:  7373:  7335:  7291:  7255:  7214:  7206:  7165:  7157:  7116:  7081:  7071:  7032:  7022:  6981:  6971:  6920:  6912:  6871:  6863:  6821:  6780:  6770:  6727:  6679:  6671:  6653:  6643:Lancet 6626:  6616:  6572:  6564:  6517:  6476:  6466:  6425:  6417:  6371:  6363:  6326:  6277:  6267:  6225:  6215:  6109:  6101:  6050:  6042:  5990:  5980:  5941:  5933:  5891:  5883:  5843:  5835:  5800:  5790:  5749:  5708:  5698:  5657:  5589:  5581:  5540:  5530:  5486:  5476:  5435:  5425:  5405:Cureus 5384:  5343:  5335:  5300:  5228:  5220:  5185:  5175:  5129:  5094:  5086:  5044:  4998:  4952:  4944:  4909:  4901:  4862:  4819:  4731:  4683:  4673:  4623:  4615:  4568:  4541:  4531:  4489:  4479:  4433:  4425:  4382:  4374:  4334:  4326:  4285:  4277:  4239:  4193:  4183:  4133:  4125:  4115:  4107:  4087:Ibrain 4049:  4018:  4010:  3968:  3960:  3925:  3917:  3865:  3809:  3799:  3755:807011 3753:  3745:  3707:  3697:  3643:  3633:  3571:  3506:  3452:  3410:  3400:  3310:18 May 3274:  3129:, and 3115:K-hole 3051:Canada 2993:CI-581 2987:and a 2901:chiral 2777:CYP2A6 2766:CYP2B6 2762:CYP3A4 2500:1-100 2418:82–291 2096:>10 1917:Action 1884:kinase 1794:, the 1778:, and 1758:other 1736:potent 1635:, and 1589:NSAIDs 1560:, and 1517:clonic 1397:Asthma 1221:asthma 1063:trance 981:SMILES 903:237.73 792:ChEMBL 761:D00711 753:D08098 440:CYP2B6 436:CYP3A4 394:Rectal 366:: 100% 325: 313: 277: 264: 125:  108:  38534:opium 37838:RCS-8 37833:RCS-4 37828:QUPIC 37803:PTI-2 37798:PTI-1 37753:MN-25 37748:MN-18 37638:CB-13 37623:APICA 36478:mAChR 36458:Xenon 36443:RB-64 36363:2-MDP 36216:(TCP) 36204:(PCP) 36193:(PCE) 36109:MXiPr 36029:NMDAR 36003:6-APB 35995:5-APB 35989:Also 35985:RH-34 35955:ALPHA 35725:18-MC 35375:alpha 35323:TOMSO 35318:TCB-2 35283:DMCPA 35253:5-TOM 35248:2-TOM 35188:TMA-6 35185:TMA-5 35182:TMA-4 35179:TMA-3 35176:TMA-2 35030:MMDMA 34980:DMMDA 34954:HOT-7 34949:HOT-2 34925:DOTFM 34905:DOiPR 34775:3C-BZ 34770:3C-AL 34333:NBOMe 33894:2C-YN 33719:2C-SE 33714:2C-Ph 33684:2C-iP 33624:2C-EF 33609:2C-CP 33604:2C-CN 33594:2C-Bu 33589:2C-Bn 33527:MIPLA 33482:LAMPA 33457:ECPLA 33064:Abuse 32963:Spain 32838:Kenya 32833:Japan 32828:Italy 32813:India 32803:Haiti 32753:China 32748:Chile 32738:Burma 32718:Benin 32698:Aruba 32627:Other 32526:Other 32389:India 32091:Other 32019:Music 31825:NORML 31685:Molly 31618:Spice 31608:APICA 31338:Vilca 31299:Molly 31269:6-APB 31239:Cocoa 31163:Crack 31114:Betel 31107:Areca 31060:Opium 30923:Freon 30678:5-HTP 30242:TeCAs 29903:SARIs 29837:NDRIs 29756:SNRIs 29698:SSRIs 28685:-type 28572:NFEPP 28279:Opium 28244:opium 27872:Xenon 27504:SM-21 27245:PB-28 27172:3-PPP 26995:4-IBP 26823:3-PPP 26525:3-PPP 26397:Semax 26036:(NOP) 26014:UPHIT 25999:RB-64 25939:ML350 25934:ML190 25894:JDTic 25869:DIPPA 25636:RB-64 25391:HS665 25256:CR665 25151:18-MC 25146:8-CAC 25122:(KOR) 24644:DSLET 24629:DPDPE 24579:DADLE 24539:BU-48 24465:(DOR) 24303:JDTic 24165:18-MC 23994:PZM21 23938:opium 23847:NFEPP 23527:DADLE 23331:(MOR) 23071:VMATs 21283:WF-33 21278:WF-31 21273:WF-23 21268:WF-11 20732:Xenon 20192:18-MC 20157:2-MDP 19985:7-CKA 19948:PEAQX 19674:B6B21 19664:AK-51 19598:-HCA) 19561:NMDAR 19484:NS102 19215:YM90K 18910:AMPAR 18820:LGICs 18527:CaCCs 18499:PcTX1 18458:ASICs 17785:VGSCs 17055:BmTx3 16908:HsTx1 16797:VGKCs 15832:VDCCs 15509:3-PPP 14610:3-PPP 14326:-like 13774:-like 13613:(and 13595:Xenon 13094:18-MC 13073:(and 12669:(and 12501:(and 12231:SSRIs 11155:AC-42 10832:S2CID 10267:46–51 10263:40–45 10255:Ronin 10228:Ronin 10133:(PDF) 10116:(PDF) 10054:(PDF) 10035:(PDF) 9925:(PDF) 9909:(PDF) 9812:S2CID 9738:S2CID 9611:S2CID 9562:2008. 9552:1995. 9254:S2CID 9161:S2CID 9012:S2CID 8969:S2CID 8926:S2CID 8879:S2CID 8784:S2CID 8652:S2CID 8511:S2CID 8410:S2CID 8350:S2CID 8160:S2CID 8068:S2CID 7863:S2CID 7659:S2CID 7379:S2CID 7212:S2CID 7163:S2CID 6918:S2CID 6869:S2CID 6677:S2CID 6570:S2CID 6423:S2CID 6369:S2CID 6107:S2CID 6048:S2CID 5962:Focus 5939:S2CID 5889:S2CID 5841:S2CID 5587:S2CID 5341:S2CID 5226:S2CID 5092:S2CID 4950:S2CID 4907:S2CID 4621:S2CID 4431:S2CID 4380:S2CID 4332:S2CID 4283:S2CID 4131:S2CID 4016:S2CID 3966:S2CID 3923:S2CID 3751:S2CID 3419:(PDF) 3378:(PDF) 2932:salts 2771:into 2541:-(–) 2529:, an 2496:TRPV1 2488:Mouse 2430:Human 2401:Human 2343:Human 2312:Human 2281:Human 2250:Human 2219:Human 2183:Human 2147:Human 2117:Human 2049:Human 2011:Human 1999:12.1 1979:Human 1950:Human 1513:tonic 1038:is a 1001:InChI 912:JSmol 772:ChEBI 554:Feces 550:: 91% 548:Urine 425:Liver 378:: 77% 372:: 93% 21:Imine 38661:GABA 38637:MDMA 38265:HZ-2 38040:GABA 37818:PX-3 37813:PX-2 37808:PX-1 37783:NNE1 37658:DMHP 37149:JWH- 36782:THCV 36418:NEFA 36231:BTCP 36197:PCPr 36180:BDPC 35930:PiPT 35915:EiPT 35910:DCPT 35839:MiPT 35811:MiPT 35632:-TMT 35609:-TMT 35596:-TMT 35521:DiPT 35498:DiPT 35442:DALT 35419:DALT 35405:α-MT 35400:α-ET 35355:pFPP 35166:TMAs 35066:4-TM 35061:3-TM 35056:4-TE 35051:3-TE 35015:MMDA 35010:MDMA 35005:MDBZ 35000:MDAI 34939:HOT- 34920:DOPR 34890:DOET 34885:DOEF 34844:4C-P 34839:4C-N 34834:4C-I 34829:4C-E 34824:4C-D 34819:4C-C 34814:4C-B 34795:3C-P 34785:3C-E 34255:NBOH 34182:NBMD 33899:2C-V 33724:2C-T 33709:2C-P 33699:2C-O 33689:2C-N 33679:2C-I 33674:2C-H 33634:2C-G 33629:2C-F 33619:2C-E 33614:2C-D 33599:2C-C 33579:2C-B 33362:F-22 33309:5-HT 32893:Oman 32853:Laos 32823:Iran 32768:Cuba 32648:Drug 32637:Drug 32573:Narc 32158:Rave 31999:Drug 31675:MDMA 31524:and 31343:Yopo 31289:MDMA 31222:Salt 31182:MDPV 31158:Coca 31146:Khat 30978:Lean 30932:Kava 30855:Wine 30850:Beer 30644:SAMe 30084:TCAs 30069:and 29804:NRIs 29666:N06A 28222:N02B 28218:N02A 27780:N01A 27489:AZ66 27484:AHD1 27425:W-18 27351:DiPT 27223:MDMA 27143:W-18 27059:DiPT 26716:MDMA 26700:IPAB 26581:CGRP 25784:ANTI 25401:HZ-2 24955:BNTX 24238:CTOP 24234:CTAP 23111:AZIK 23100:MDMA 22589:PPPA 22332:SRIs 22321:SERT 21865:PPPA 21622:NRIs 21122:MDPV 20969:DRIs 20827:MPEP 20767:-αAA 20625:Zinc 20452:PCPr 20422:NEFA 20108:PNQX 20038:DNQX 20025:CNQX 19958:PPDA 19943:PBPD 19813:DHEA 19798:DHEA 19708:DHPG 19659:ACPD 19649:ACBD 19613:NMDA 19579:AMAA 19479:NBQX 19454:GAMS 19449:DNQX 19439:CNQX 19357:ATPA 19352:AMPA 19190:PNQX 19185:NBQX 19160:GAMS 19150:DNQX 19140:CNQX 19125:ATPO 19085:PEPA 18943:BOAA 18938:AMPA 18833:here 18831:See 18808:here 18806:See 18795:TRPs 18626:CFTR 18553:DIDS 18394:ENaC 18315:mint 17703:K2Ps 17574:GIRK 17419:GIRK 17285:IRKs 17001:hERG 16349:Z944 16275:Z160 15544:EEDQ 14288:EEDQ 14076:DPTQ 14071:DETQ 14060:PAMs 13275:DHβE 13076:NAMs 12672:PAMs 12065:PBID 11767:DIBD 11340:RS86 11175:AF30 11026:PMID 10987:PMID 10965:2015 10937:2021 10919:ISBN 10894:PMID 10867:PMID 10824:PMID 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Index

Imine

(S)-Ketamine ball-and-stick model
Trade names
AHFS
Drugs.com
Monograph
License data
DailyMed
Ketamine
FDA
Ketamine
Pregnancy
category

Addiction
liability

Routes of
administration

Drug class
NMDA receptor antagonist
general anesthetic
dissociative hallucinogen
analgesic
antidepressant
ATC code
N01AX03
WHO
Legal status
S8
Class C1
Schedule I
Anlage III
Class B

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