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Vascular tumor

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vessels in lobules that are scattered in the skin, and that sometimes reach into the subcutaneous tissue, and have lymph vessels on the periphery. Their growth is slow to begin with, and progresses to a stable size. They show a high rate of spontaneous regression, particularly in congenital and early-onset cases. They typically have a deep nodular component sometimes extending into the subcutaneous tissue, fascia, and muscle, and can sometimes be painful. Tufted angiomas are associated with arteriovenous malformations.
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Johnson, EF; Davis, DM; Tollefson, MM; Fritchie, K; Gibson, LE (April 2018). "Vascular Tumors in Infants: Case Report and Review of Clinical, Histopathologic, and Immunohistochemical Characteristics of Infantile Hemangioma, Pyogenic Granuloma, Noninvoluting Congenital Hemangioma, Tufted Angioma, and
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Congenital hemangiomas are present and fully formed at birth, and only account for 2% of the hemangiomas. They do not have the postnatal phase of proliferation common to infantile hemangiomas. There are two main variants of congenital hemangioma: non-involuting, and rapidly involuting (beginning in
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are hereditary hemangiomas found in infants from birth to five years of age, however they may occur in adults. They are found on the neck, shoulders, and trunk as rounded nodules. Tufted angiomas are usually poorly defined lesions of purple colouration. The tumors are of tufts of capillary-sized
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seems to be a major trigger for this. Infantile hemangiomas are easily diagnosed, and little if any aggressive treatment is needed. They are characterised by rapid growth in the first few months, followed by spontaneous regression in early childhood.
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KHE is characterised by nodules of tumor-like spindled endothelial cells. Unlike infantile hemangiomas, KHEs have a high mortality rate. Both KHEs and TAs are unique in that they carry the risk of the development of
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van Vugt, LJ; van der Vleuten, CJM; Flucke, U; Blokx, WAM (June 2017). "The utility of GLUT1 as a diagnostic marker in cutaneous vascular anomalies: A review of literature and recommendations for daily practice".
360:. KHEs are described as locally destructive because they can infiltrate underlying muscle and fat. They are often seen to overlap with tufted angiomas (TAs) but TAs may be a milder, benign counterpart. 439: 327:
The origin of tufted angiomas is not clear but markers on the cells suggest a possible derivation from the endothelial cells of lymph vessels. They are also associated with the local secretion of
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are the most common type of vascular tumor to affect babies, accounting for 90% of hemangiomas. They are characterised by the abnormal proliferation of endothelial cells and of deviant
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Darrow, DH; Greene, AK; Mancini, AJ; Nopper, AJ; SECTION ON DERMATOLOGY, SECTION ON OTOLARYNGOLOGY–HEAD AND NECK SURGERY, and SECTION ON PLASTIC, SURGERY. (October 2015).
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Victoria Martínez, AM; Cubells Sánchez, L; Esteve Martínez, A; Estela Cubells, JR; Febrer Bosch, I; Alegre de Miquel, V; Oliver Martínez, V (September 2015). "".
245:. Congenital hemangiomas can also be distinguished from infantile hemangiomas in that neither variant of congenital hemangioma expresses the glucose transporter 443: 661: 1303: 17: 162:. Vascular tumors can be further subclassified as being benign, borderline or aggressive, and malignant. Vascular tumors are described as 1205: 1125: 1080: 949:
Putra, J; Gupta, A (June 2017). "Kaposiform haemangioendothelioma: a review with emphasis on histological differential diagnosis".
1190: 1361: 895:"The importance of early diagnosis and treatment of kaposiform hemangioendothelioma complicated by Kasabach-Merritt phenomenon" 731: 1019:
Ghose, A; Guha, G; Kundu, R; Tew, J; Chaudhary, R (June 2017). "CNS Hemangiopericytoma: A Systematic Review of 523 Patients".
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Vivas-Colmenares, GV; Ramirez-Villar, GL; Bernabeu-Wittel, J; Matute de Cardenas, JA; Fernandez-Pineda, I (January 2015).
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Croteau, SE; Gupta, D (September 2016). "The clinical spectrum of kaposiform hemangioendothelioma and tufted angioma".
1335: 1151: 797: 356:(KHEs) are borderline, locally destructive vascular tumors. They are named after their resemblance to the lesions of 1185: 1130: 413: 385: 1135: 1110: 1195: 1140: 1120: 1422: 1145: 1073: 369: 1168: 1412: 1330: 70: 1349: 1286: 1066: 1237: 1313: 1276: 1232: 1200: 892: 274: 849: 655: 159: 1259: 1227: 1222: 1115: 340: 220: 215: 109: 8: 1180: 357: 113: 1417: 1298: 1163: 1044: 919: 894: 875: 708: 681: 542: 517: 483: 389: 305: 1366: 1325: 1036: 1001: 966: 924: 879: 867: 793: 767: 713: 643: 593: 547: 475: 393: 363:
KHEs show as a red or purple expanding mass of soft tissue, found mostly in infants.
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RöFo: Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
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Sadick, M; MĂĽller-Wille, R; Wildgruber, M; Wohlgemuth, WA (September 2018).
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Wildgruber, M; Sadick, M; MĂĽller-Wille, R; Wohlgemuth, WA (13 March 2019).
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that affect angiogenesis and promote the development of vascular lobules.
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A vascular tumor typically grows quickly by the proliferation of
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that grow in response to a stimulus, such as trauma, or a local
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the first year of life). A third variant is also recognised as
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The most common type of reactive proliferative tumors are
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Vascular tumors make up one of the classifications of
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Some cases have been associated with a mild form of
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A vascular tumor may be described in terms of being
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Some vascular tumors can be associated with serious
285:A range of benign vascular tumors are described as 202:The most common type of benign vascular tumors are 622:"Diagnosis and Management of Infantile Hemangioma" 1018: 518:"Classification of Vascular Anomalies: An Update" 1404: 886: 380:Malignant vascular tumors are rare, and include 1304:Intravascular papillary endothelial hyperplasia 787: 792:(Tenth ed.). Elsevier. pp. 392–396. 1074: 515: 128:refers to any type of benign vascular tumor. 27:Tumor originating from blood or lymph vessels 1088: 983: 682:"Vascular tumors in infants and adolescents" 675: 673: 671: 660:: CS1 maint: multiple names: authors list ( 845: 843: 841: 839: 837: 1081: 1067: 986:Seminars in Cutaneous Medicine and Surgery 948: 783: 781: 516:Steiner, JE; Drolet, BA (September 2017). 96:; a soft tissue growth that can be either 69: 41: 918: 707: 697: 668: 637: 587: 565: 563: 561: 541: 511: 509: 507: 505: 503: 501: 499: 497: 293:. They can also form infrequently during 88:where a tumor forms from cells that make 944: 942: 940: 938: 834: 615: 613: 611: 609: 607: 460:The American Journal of Dermatopathology 344: 235: 177: 977: 811: 809: 778: 742: 432: 209: 14: 1405: 1362:Multifocal lymphangioendotheliomatosis 899:Dermatology Practical & Conceptual 558: 494: 104:. Examples of vascular tumors include 1062: 1021:American Journal of Clinical Oncology 1012: 935: 788:Kumar, V; Abbas, A; Aster, J (2018). 604: 440:"Dorlands Medical Dictionary:angioma" 297:as a hormonal reaction affecting the 280: 135:, making correct diagnosis critical. 1159:Proliferating angioendotheliomatosis 806: 522:Seminars in Interventional Radiology 724: 259: 24: 458:Kaposiform Hemangioendothelioma". 406: 25: 1434: 1336:Acquired progressive lymphangioma 442:. 2 February 2009. Archived from 386:epithelioid hemangioendotheliomas 315: 149: 54:, a benign type of vascular tumor 752:Pathology, Research and Practice 414:"NCI Dictionary of Cancer Terms" 354:Kaposiform hemangioendotheliomas 182:A pyogenic granuloma on a thumb. 166:, and vascular malformations as 1111:Blue rubber bleb nevus syndrome 349:Kaposiform hemangioendothelioma 18:Kaposiform hemangioendothelioma 450: 287:reactive proliferative lesions 13: 1: 399: 334: 310:lobular capillary hemangiomas 1206:Immunosuppression-associated 1169:Infantile hemangiopericytoma 1033:10.1097/COC.0000000000000146 963:10.1016/j.pathol.2017.03.001 864:10.1016/j.anpedi.2014.10.018 472:10.1097/DAD.0000000000000983 375: 7: 1331:Lymphangioma circumscriptum 273:are vascular tumors of the 10: 1439: 338: 263: 213: 1375: 1312: 1096: 764:10.1016/j.prp.2017.04.023 699:10.1186/s13244-019-0718-6 418:National Cancer Institute 370:Kasabach–Merritt syndrome 197: 58: 49: 40: 35: 1350:Lymphangioleiomyomatosis 1191:African lymphadenopathic 1090:Tumours of blood vessels 998:10.12788/j.sder.2016.048 732:"Congenital haemangioma" 173: 158:. The other grouping is 133:blood-clotting disorders 790:Robbins basic pathology 1277:Universal angiomatosis 1243:Targeted hemosiderotic 1126:Endovascular papillary 639:10.1542/peds.2015-2485 534:10.1055/s-0037-1604295 350: 275:central nervous system 225:blood vessel formation 183: 160:vascular malformations 686:Insights into Imaging 348: 236:Congenital hemangioma 221:Infantile hemangiomas 181: 110:hemangioendotheliomas 1423:Anatomical pathology 1116:Hemangioendothelioma 365:Under the microscope 341:Hemangioendothelioma 243:partially involuting 216:Infantile hemangioma 210:Infantile hemangioma 911:10.5826/dpc.0501a18 852:Anales de Pediatria 589:10.1055/a-0620-8925 446:on 2 February 2009. 390:hemangiopericytomas 388:. Other types are 306:pyogenic granulomas 144:poorly vascularized 140:highly vascularized 1413:Vascular anomalies 1299:Pyogenic granuloma 1164:Hemangiopericytoma 394:lymphangiosarcomas 351: 281:Pyogenic granuloma 184: 156:vascular anomalies 1400: 1399: 1367:Lymphangiomatosis 1326:lymphangiosarcoma 1186:African cutaneous 821:meshb.nlm.nih.gov 420:. 2 February 2011 271:Hemangioblastomas 227:or architecture. 188:endothelial cells 122:hemangioblastomas 114:Kaposi's sarcomas 78: 77: 30:Medical condition 16:(Redirected from 1430: 1213:Hemangioblastoma 1181:Kaposi's sarcoma 1083: 1076: 1069: 1060: 1059: 1053: 1052: 1016: 1010: 1009: 981: 975: 974: 946: 933: 932: 922: 890: 884: 883: 847: 832: 831: 829: 827: 813: 804: 803: 785: 776: 775: 746: 740: 739: 728: 722: 721: 711: 701: 677: 666: 665: 659: 651: 641: 632:(4): e1060-104. 617: 602: 601: 591: 567: 556: 555: 545: 513: 492: 491: 454: 448: 447: 436: 430: 429: 427: 425: 410: 358:Kaposi's sarcoma 266:Hemangioblastoma 260:Hemangioblastoma 254:thrombocytopenia 168:nonproliferative 86:vascular anomaly 74: 73: 45: 33: 32: 21: 1438: 1437: 1433: 1432: 1431: 1429: 1428: 1427: 1403: 1402: 1401: 1396: 1371: 1308: 1196:AIDS-associated 1106:Hemangiosarcoma 1092: 1087: 1057: 1056: 1017: 1013: 982: 978: 947: 936: 891: 887: 848: 835: 825: 823: 815: 814: 807: 800: 786: 779: 747: 743: 736:www.gosh.nhs.uk 730: 729: 725: 678: 669: 653: 652: 618: 605: 568: 559: 514: 495: 455: 451: 438: 437: 433: 423: 421: 412: 411: 407: 402: 378: 343: 337: 321:Tufted angiomas 318: 283: 268: 262: 238: 218: 212: 200: 190:. Most are not 176: 152: 68: 31: 28: 23: 22: 15: 12: 11: 5: 1436: 1426: 1425: 1420: 1415: 1398: 1397: 1395: 1394: 1389: 1379: 1377: 1373: 1372: 1370: 1369: 1364: 1359: 1357:Cystic hygroma 1354: 1353: 1352: 1340: 1339: 1338: 1333: 1318: 1316: 1310: 1309: 1307: 1306: 1301: 1296: 1295: 1294: 1289: 1279: 1274: 1273: 1272: 1267: 1262: 1257: 1247: 1246: 1245: 1240: 1235: 1230: 1225: 1215: 1210: 1209: 1208: 1203: 1198: 1193: 1188: 1178: 1173: 1172: 1171: 1161: 1156: 1155: 1154: 1149: 1143: 1138: 1133: 1128: 1123: 1113: 1108: 1102: 1100: 1094: 1093: 1086: 1085: 1078: 1071: 1063: 1055: 1054: 1027:(3): 223–227. 1011: 976: 957:(4): 356–362. 934: 885: 833: 817:"MeSH Browser" 805: 798: 777: 758:(6): 591–597. 741: 723: 667: 603: 582:(9): 825–835. 557: 528:(3): 225–232. 493: 466:(4): 231–239. 449: 431: 404: 403: 401: 398: 377: 374: 339:Main article: 336: 333: 329:growth factors 317: 316:Tufted angioma 314: 308:also known as 282: 279: 264:Main article: 261: 258: 237: 234: 229:Hypoxic stress 214:Main article: 211: 208: 199: 196: 175: 172: 151: 150:Classification 148: 82:vascular tumor 76: 75: 62: 56: 55: 47: 46: 38: 37: 36:Vascular tumor 29: 26: 9: 6: 4: 3: 2: 1435: 1424: 1421: 1419: 1416: 1414: 1411: 1410: 1408: 1393: 1390: 1388: 1384: 1381: 1380: 1378: 1374: 1368: 1365: 1363: 1360: 1358: 1355: 1351: 1348: 1347: 1346: 1345: 1341: 1337: 1334: 1332: 1329: 1328: 1327: 1323: 1320: 1319: 1317: 1315: 1311: 1305: 1302: 1300: 1297: 1293: 1290: 1288: 1285: 1284: 1283: 1282:Angiokeratoma 1280: 1278: 1275: 1271: 1268: 1266: 1263: 1261: 1258: 1256: 1253: 1252: 1251: 1248: 1244: 1241: 1239: 1236: 1234: 1231: 1229: 1226: 1224: 1221: 1220: 1219: 1216: 1214: 1211: 1207: 1204: 1202: 1199: 1197: 1194: 1192: 1189: 1187: 1184: 1183: 1182: 1179: 1177: 1174: 1170: 1167: 1166: 1165: 1162: 1160: 1157: 1153: 1150: 1147: 1144: 1142: 1139: 1137: 1134: 1132: 1129: 1127: 1124: 1122: 1119: 1118: 1117: 1114: 1112: 1109: 1107: 1104: 1103: 1101: 1099: 1095: 1091: 1084: 1079: 1077: 1072: 1070: 1065: 1064: 1061: 1050: 1046: 1042: 1038: 1034: 1030: 1026: 1022: 1015: 1007: 1003: 999: 995: 992:(3): 147–52. 991: 987: 980: 972: 968: 964: 960: 956: 952: 945: 943: 941: 939: 930: 926: 921: 916: 912: 908: 904: 900: 896: 889: 881: 877: 873: 869: 865: 861: 857: 853: 846: 844: 842: 840: 838: 822: 818: 812: 810: 801: 799:9780323353175 795: 791: 784: 782: 773: 769: 765: 761: 757: 753: 745: 737: 733: 727: 719: 715: 710: 705: 700: 695: 691: 687: 683: 676: 674: 672: 663: 657: 649: 645: 640: 635: 631: 627: 623: 616: 614: 612: 610: 608: 599: 595: 590: 585: 581: 577: 573: 566: 564: 562: 553: 549: 544: 539: 535: 531: 527: 523: 519: 512: 510: 508: 506: 504: 502: 500: 498: 489: 485: 481: 477: 473: 469: 465: 461: 453: 445: 441: 435: 419: 415: 409: 405: 397: 395: 391: 387: 383: 382:angiosarcomas 373: 371: 366: 361: 359: 355: 347: 342: 332: 330: 325: 322: 313: 311: 307: 302: 300: 296: 292: 288: 278: 276: 272: 267: 257: 255: 250: 248: 244: 233: 230: 226: 222: 217: 207: 205: 195: 193: 192:birth defects 189: 180: 171: 169: 165: 164:proliferative 161: 157: 147: 145: 141: 136: 134: 129: 127: 123: 119: 118:angiosarcomas 115: 111: 107: 103: 99: 95: 94:lymph vessels 91: 87: 83: 72: 66: 63: 61: 57: 53: 48: 44: 39: 34: 19: 1392:Angiofibroma 1387:angiosarcoma 1342: 1322:Lymphangioma 1238:Microvenular 1152:Spindle cell 1098:Blood vessel 1089: 1024: 1020: 1014: 989: 985: 979: 954: 950: 902: 898: 888: 858:(3): 201–8. 855: 851: 824:. 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Index

Kaposiform hemangioendothelioma

hemangioma
Specialty
Oncology
Edit this on Wikidata
vascular anomaly
blood
lymph vessels
benign
malignant
hemangiomas
hemangioendotheliomas
Kaposi's sarcomas
angiosarcomas
hemangioblastomas
angioma
blood-clotting disorders
vascular anomalies
vascular malformations

endothelial cells
birth defects
hemangiomas
Infantile hemangioma
Infantile hemangiomas
blood vessel formation
Hypoxic stress
GLUT 1
thrombocytopenia

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