325:-fetoprotein levels are milder than those found in patients with hepatoblastomas. Infantile hepatic hemangioendothelioma is strongly suggested by the presence of a vascular lesion on imaging studies. A complex, heterogeneous mass is often seen on ultrasonograms; a complex tumor that lacks central enhancement can be seen on CT scans; and the vascular nature of the lesion along with dilation of the aorta proximal to the origin of the celiac artery and a decrease in the diameter distally, indicating significant shunting, is seen on angiograms. Because most hemangioendotheliomas in infants sponanteously involute and regress within the first 12 to 18 months of life, asymptomatic lesions are generally managed conservatively. Infants who have severe anemia and/or thrombocytopenia can be given blood products; for those who have cardiac failure, diuretics and digoxin are often given. To stop further growth and to speed regression of lesions in infants with more significant clinical sequelae, treatment with corticosteroids or interferon-Ξ±-2a is administered. To slow the growth of tumors that are rapidly enlarging, chemotherapy and radiation therapy have been used. Surgical resection, partial hepatectomy, and embolization of afferent vessels should be considered for severe cases.
353:
56:
333:
29:
373:
307:
phases: an initial rapid growth phase, which is followed by a period of spontaneous involution (usually within the first 12 to 18 months of life). Detection of the hemangioendothelioma within the first 6 months of life is attributed to the initial rapid growth during this time; however, the tumor has been detected with fetal ultrasonography. Histopathologically, there are 2 types of hepatic hemangioendotheliomas:
220:(also known as "Infantile kaposiform hemangioendothelioma") is an uncommon vascular tumor, first described by Niedt, Greco, et al. (Hemangioma with Kaposi's sarcoma-like features: report of two cases.(Niedt GW, Greco MA, Wieczorek R, Blanc WA, Knowles DM 2nd. that affects infants and young children, with rare cases having also been reported in adults. Pediatr Pathol. 1989;9(5):567-75.)
400:
have all been used to treat these masses, although studies on survival have yet to be conducted to delineate various treatment regimens. Kaposiform hemangioendothelioma might respond to chemotherapy or antiangiogenic therapies. Recently propanolol and steroids have been shown to be very effective in
194:, and commonly presents in a child or young adult who develops blue nodules of firm consistency on a distal extremity. These tumors were reclassified by Dr. Weiss in 1996 as "spindle cell hemangioma", rather than hemangioendothelioma, due to the excellent prognosis observed in a group of 78 patients.
306:
because of extensive arteriovenous shunting within the lesion. It is the third most common liver tumor in children, the most common benign vascular tumor of the liver in infancy, and the most common symptomatic liver tumor during the first 6 months of life. These hemangioendotheliomas have 2 growth
320:
In children, distinguishing between a primary malignant liver tumor (hepatoblastoma) and a benign primary hepatic lesion (hemangioendothelioma) is crucial. The absence of urinary catecholamines supports the diagnosis of hemangioendothelioma. In patients with hemangioendotheliomas, elevations in
226:, also known as "Dabska tumor", "papillary intralymphatic angioendothelioma" (PILA), "Dabska-type hemangioendothelioma", "hobnail hemangioendothelioma", and "malignant endovascular papillary angioendothelioma", is a rare
352:
1135:
332:
855:
Yamada A, Uematsu K, Yasoshima H, Sakurai K, Hori K, Ohya M, Ohkubo E, Ogasawara H (Feb 1998). "Endovascular papillary angioendothelioma (Dabska tumor) in an elderly woman".
310:
Type I: Hemagioendotheliomas of this type have multiple vascular channels that are formed by an immature endothelial lining with stromal separation from bile ductules.
174:
in 2003. These tumors are so named because their histologic appearance resembles a proliferation of epithelioid cells, with polygonal shape and eosinophilic cytoplasm.
249:
tumor classification, there is uncertainty as to whether EPA is a distinct entity or a heterogenous group of tumours. The lesion usually presents as a slow-growing
578:
Perkins P, Weiss SW (October 1996). "Spindle cell hemangioendothelioma. An analysis of 78 cases with reassessment of its pathogenesis and biologic behavior".
1084:
782:
Argani P, Athanasian E (Sep 1997). "Malignant endovascular papillary angioendothelioma (Dabska tumor) arising within a deep intramuscular hemangioma".
997:
977:
1753:
372:
388:
Treatment is varied and depends on the site and extent of tumor involvement, sites of metastasis, and specific individual factors. Surgical
1142:
1655:
1575:
1190:
1530:
313:
Type II: These hemangioendotheliomas have an appearance that is more disorganized and hypercellular, and there are no bile ductules.
1640:
1811:
812:
McCarthy EF, Lietman S, Argani P, Frassica FJ (Feb 1999). "Endovascular papillary angioendothelioma (Dabska tumor) of bone".
515:
1608:
620:"Strong ERG Positivity in Papillary Intralymphatic Angioendothelioma of the Testis of a 24-Year-Old Male: A Case Report"
1692:
898:
Patterson K, Chandra RS (Jul 1985). "Malignant endovascular papillary angioendothelioma. Cutaneous borderline tumor".
1785:
1601:
1490:
482:
533:"Spindle cell hemangioendothelioma. A low-grade angiosarcoma resembling a cavernous hemangioma and Kaposi's sarcoma"
1635:
1580:
1232:
162:
733:"Dabska tumor (endovascular papillary angioendothelioma) of testis: a case report with brief review of literature"
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1014:
Verma, Saurav; Dhamija, Ekta; Barwad, Adarsh; Kumar, Venkatesan S.; Rastogi, Sameer (30 July 2020).
55:
1799:
1736:
1516:
1092:
1687:
418:
Billings SD, Folpe AL, Weiss SW (January 2003). "Epithelioid sarcoma-like hemangioendothelioma".
1763:
1726:
1682:
1650:
1284:
958:
298:
is a rare benign vascular tumour arising from mesenchymal tissue and is usually located in the
101:
1463:
1403:
1246:
261:
of the head, neck, or extremity, of infants or young children. However, EPA has involved the
1709:
1677:
1672:
1319:
1174:
1016:"A case report of Kaposiform haemangioendothelioma; response with propranolol and steroids"
273:
170:
of intermediate malignancy that was first described by Steven
Billings, Andrew Folpe, and
8:
1630:
1335:
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363:
258:
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69:
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39:
of a kaposiform hemangioendothelioma with "glomeruloid" nodules of endothelial cells.
884:
841:
714:
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1037:
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234:
227:
685:
Fukunaga M (Oct 1998). "Endovascular papillary angioendothelioma (Dabska tumor)".
28:
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1271:
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1001:
981:
338:
Low power photomicrograph of an endovascular papillary angioendothelioma showing
303:
125:
1806:
1719:
1714:
1704:
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1211:
1182:
1159:
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167:
89:
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230:
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92:
that commonly present with an enlarging mass and most commonly involve the
85:
925:
Roos J, Pfiffner R, Stallmach T, Stuckmann G, Marincek B, Willi U (2003).
911:
876:
825:
795:
706:
636:
599:
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339:
1741:
1625:
943:
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184:
typically occurring in adults, although it has been described in infancy.
117:
1076:
204:, first described in 1994, presenting as a slow-growing exophytic mass,
1667:
289:
113:
81:
36:
1120:
285:
532:
262:
104:, although many other body sites have been reported, including the
49:
1832:
1699:
975:
What's Your
Diagnosis? Newborn with abdominal mass and distention
506:
Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007).
133:
200:(also known as a "Hobnail hemangioendothelioma") is a low-grade
1793:
378:
Characteristic budding, hobnail-like endothelial cells visible.
343:
281:
270:
266:
205:
121:
924:
854:
811:
299:
284:, and has been found in adults. Some reports indicate a good
250:
238:
97:
93:
277:
269:
tissue as a neoplastic transformation of a larger existing
254:
129:
109:
105:
674:
Schwartz, RA. Dabska Tumor. Medscape, updated: Apr 5, 2013
190:) is a vascular tumor that was first described in 1986 by
617:
1013:
358:
High power view showing a vascular tumor with cuboidal
80:
They have been described as masses that fall between a
473:
James, William; Berger, Timothy; Elston, Dirk (2005).
1468:
Limb CM + congenital non-progressive limb overgrowth
1066:
730:
475:
417:
969:
967:
1854:
897:
781:
1754:Intravascular papillary endothelial hyperplasia
1272:Cutaneous and/or mucosal CM ("port-wine" stain)
1004:. Condultant for Pediatricians. 2010;9:168-173.
984:. Consultant for Pediatricians. 2010;9:168-173.
807:
805:
964:
501:
499:
497:
495:
493:
491:
1524:
1136:
618:Schultheis AM, Sandmann M, Steurer S (2013).
530:
469:
467:
465:
463:
461:
459:
457:
1538:
1175:Infantile hemangioma / Hemangioma of infancy
802:
613:
611:
609:
577:
411:
157:Hemangioendotheliomas may be classified as:
1370:Familial intraosseous vascular malformation
993:Banks T, Podraza J. What's Your Diagnosis?
731:Bhatia A, Nada R, Kumar Y, Menon P (2006).
488:
1531:
1517:
1143:
1129:
995:Newborn with abdominal mass and distention
775:
684:
669:
667:
665:
454:
54:
27:
1041:
1031:
942:
891:
758:
748:
645:
635:
606:
571:
524:
1327:βAcquiredβ progressive lymphatic anomaly
726:
724:
224:Endovascular papillary angioendothelioma
678:
662:
1855:
1812:Multifocal lymphangioendotheliomatosis
1150:
848:
1512:
1124:
721:
75:
1609:Proliferating angioendotheliomatosis
1438:Capillary-arteriovenous malformation
302:. It often presents in infancy with
144:Possibly Bartonella spp bacteraemia
13:
869:10.1111/j.1440-1827.1998.tb03887.x
699:10.1111/j.1440-1827.1998.tb03847.x
362:lining the vessels. Few entrapped
14:
1879:
1786:Acquired progressive lymphangioma
1491:Bannayan-Riley-Ruvalcaba syndrome
1062:
401:kaposiform hemangioendothelioma.
188:Spindle-cell hemangioendothelioma
152:
1233:Epithelioid hemangioendothelioma
1205:Locally aggressive or borderline
927:"Infantile hemangioendothelioma"
592:10.1097/00000478-199610000-00004
549:10.1097/00000478-198608000-00001
432:10.1097/00000478-200301000-00006
371:
351:
331:
163:Epithelioid hemangioendothelioma
1561:Blue rubber bleb nevus syndrome
1476:Macrocephaly - CM (M-CM / MCAP)
1446:Associated with other anomalies
1367:Cerebral cavernous malformation
1360:Blue rubber bleb nevus syndrome
1212:Kaposiform hemangioendothelioma
1007:
987:
918:
217:Kaposiform hemangioendothelioma
1310:Generalized lymphatic anomaly
531:Weiss SW, Enzinger FM (1986).
296:Infantile hemangioendothelioma
178:Composite hemangioendothelioma
1:
1435:Lymphatic-venous malformation
1373:Verrucous venous malformation
404:
198:Retiform hemangioendothelioma
1656:Immunosuppression-associated
1619:Infantile hemangiopericytoma
1313:Kaposiform lymphangiomatosis
1289:Incorrect name: Lymphangioma
1285:Lymphatic malformations (LM)
383:
147:
72:of intermediate malignancy.
7:
1781:Lymphangioma circumscriptum
1460:Servelle-Martorell syndrome
1382:Arteriovenous malformations
1356:Familial VM cutaneo-mucosal
245:. Although included in the
241:have been described in the
10:
1884:
1479:Microcephaly - CM (MICCAP)
1453:Klippel-Trenaunay syndrome
1033:10.1186/s13569-020-00134-8
1825:
1762:
1546:
1445:
1428:
1402:
1380:
1346:
1283:
1261:
1254:
1245:
1220:
1204:
1167:
1158:
1070:
1020:Clinical Sarcoma Research
508:Dermatology: 2-Volume Set
247:World Health Organization
43:
35:
26:
21:
1800:Lymphangioleiomyomatosis
1641:African lymphadenopathic
1540:Tumours of blood vessels
1364:Glomuvenous malformation
477:. (10th ed.). Saunders.
237:. Approximately 30 such
139:
1262:Capillary malformations
1187:Spindle-cell hemangioma
366:are also noted (arrow).
1727:Universal angiomatosis
1693:Targeted hemosiderotic
1576:Endovascular papillary
1247:Vascular malformations
1191:Epithelioid hemangioma
750:10.1186/1746-1596-1-12
102:musculoskeletal system
1464:Sturge-Weber syndrome
1457:Parkes Weber Syndrome
1404:Arteriovenous fistula
1336:Nonne-Milroy syndrome
1179:Congenital hemangioma
826:10.1007/s002560050482
292:is occasionally seen.
66:Hemangioendotheliomas
1566:Hemangioendothelioma
1347:Venous malformations
1320:Gorham-Stout disease
973:Banks T, Podraza J.
944:10.1148/rg.236035024
510:. St. Louis: Mosby.
364:seminiferous tubules
274:cavernous hemangioma
259:subcutaneous tissues
22:Hemangioendothelioma
1296:Common (cystic) LM
900:Arch Pathol Lab Med
784:Arch Pathol Lab Med
637:10.1155/2013/531479
580:Am. J. Surg. Pathol
420:Am. J. Surg. Pathol
1868:Vascular neoplasia
1863:Vascular anomalies
1749:Pyogenic granuloma
1614:Hemangiopericytoma
1331:Primary lymphedema
1196:Pyogenic granuloma
1152:Vascular anomalies
1000:2010-07-02 at the
980:2010-07-02 at the
243:medical literature
235:lymphatic channels
192:Sharon Weiss, M.D.
76:Signs and symptoms
70:vascular neoplasms
1850:
1849:
1817:Lymphangiomatosis
1776:lymphangiosarcoma
1636:African cutaneous
1506:
1505:
1502:
1501:
1472:Maffucci syndrome
1424:
1423:
1241:
1240:
1118:
1117:
517:978-1-4160-2999-1
63:
62:
16:Medical condition
1875:
1663:Hemangioblastoma
1631:Kaposi's sarcoma
1533:
1526:
1519:
1510:
1509:
1487:Proteus syndrome
1290:
1259:
1258:
1252:
1251:
1165:
1164:
1145:
1138:
1131:
1122:
1121:
1068:
1067:
1056:
1055:
1045:
1035:
1011:
1005:
991:
985:
971:
962:
956:
946:
922:
916:
915:
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889:
888:
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846:
845:
809:
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799:
779:
773:
772:
762:
752:
728:
719:
718:
682:
676:
671:
660:
659:
649:
639:
615:
604:
603:
586:(10): 1196β204.
575:
569:
568:
537:Am J Surg Pathol
528:
522:
521:
503:
486:
471:
452:
451:
415:
375:
355:
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68:are a family of
59:
58:
31:
19:
18:
1883:
1882:
1878:
1877:
1876:
1874:
1873:
1872:
1853:
1852:
1851:
1846:
1821:
1758:
1646:AIDS-associated
1556:Hemangiosarcoma
1542:
1537:
1507:
1498:
1483:CLOVES syndrome
1441:
1420:
1398:
1376:
1342:
1324:Channel type LM
1305:Mixed cystic LM
1288:
1287:
1279:
1237:
1216:
1200:
1160:Vascular tumors
1154:
1149:
1119:
1114:
1113:
1079:
1065:
1060:
1059:
1012:
1008:
1002:Wayback Machine
992:
988:
982:Wayback Machine
972:
965:
923:
919:
896:
892:
853:
849:
814:Skeletal Radiol
810:
803:
780:
776:
729:
722:
683:
679:
672:
663:
624:Case Rep Pathol
616:
607:
576:
572:
529:
525:
518:
504:
489:
472:
455:
416:
412:
407:
386:
379:
376:
367:
356:
347:
336:
324:
304:cardiac failure
180:is a low-grade
166:is an uncommon
155:
150:
142:
126:retroperitoneum
90:vascular tumors
78:
53:
17:
12:
11:
5:
1881:
1871:
1870:
1865:
1848:
1847:
1845:
1844:
1839:
1829:
1827:
1823:
1822:
1820:
1819:
1814:
1809:
1807:Cystic hygroma
1804:
1803:
1802:
1790:
1789:
1788:
1783:
1768:
1766:
1760:
1759:
1757:
1756:
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1729:
1724:
1723:
1722:
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1690:
1685:
1680:
1675:
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1653:
1648:
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1628:
1623:
1622:
1621:
1611:
1606:
1605:
1604:
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1588:
1583:
1578:
1573:
1563:
1558:
1552:
1550:
1544:
1543:
1536:
1535:
1528:
1521:
1513:
1504:
1503:
1500:
1499:
1497:
1496:
1495:CLAPO syndrome
1493:
1488:
1485:
1480:
1477:
1474:
1469:
1466:
1461:
1458:
1455:
1449:
1447:
1443:
1442:
1440:
1439:
1436:
1432:
1430:
1426:
1425:
1422:
1421:
1419:
1418:
1415:
1412:
1408:
1406:
1400:
1399:
1397:
1396:
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1390:
1386:
1384:
1378:
1377:
1375:
1374:
1371:
1368:
1365:
1362:
1357:
1354:
1350:
1348:
1344:
1343:
1341:
1340:
1339:
1338:
1328:
1325:
1322:
1316:
1315:
1314:
1308:
1307:
1306:
1303:
1302:Microcystic LM
1300:
1299:Macrocystic LM
1293:
1291:
1281:
1280:
1278:
1277:
1274:
1269:
1265:
1263:
1256:
1249:
1243:
1242:
1239:
1238:
1236:
1235:
1230:
1224:
1222:
1218:
1217:
1215:
1214:
1208:
1206:
1202:
1201:
1199:
1198:
1193:
1188:
1185:
1183:Tufted angioma
1180:
1177:
1171:
1169:
1162:
1156:
1155:
1148:
1147:
1140:
1133:
1125:
1116:
1115:
1112:
1111:
1100:
1089:
1080:
1075:
1074:
1072:
1071:Classification
1064:
1063:External links
1061:
1058:
1057:
1006:
986:
963:
937:(6): 1649β55.
917:
890:
847:
801:
774:
720:
677:
661:
605:
570:
523:
516:
487:
453:
409:
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403:
385:
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293:
221:
213:
195:
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168:vascular tumor
154:
153:Classification
151:
149:
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141:
138:
77:
74:
61:
60:
47:
41:
40:
33:
32:
24:
23:
15:
9:
6:
4:
3:
2:
1880:
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1761:
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1735:
1734:
1733:
1732:Angiokeratoma
1730:
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1541:
1534:
1529:
1527:
1522:
1520:
1515:
1514:
1511:
1494:
1492:
1489:
1486:
1484:
1481:
1478:
1475:
1473:
1470:
1467:
1465:
1462:
1459:
1456:
1454:
1451:
1450:
1448:
1444:
1437:
1434:
1433:
1431:
1427:
1416:
1413:
1410:
1409:
1407:
1405:
1401:
1394:
1391:
1388:
1387:
1385:
1383:
1379:
1372:
1369:
1366:
1363:
1361:
1358:
1355:
1352:
1351:
1349:
1345:
1337:
1334:
1333:
1332:
1329:
1326:
1323:
1321:
1317:
1312:
1311:
1309:
1304:
1301:
1298:
1297:
1295:
1294:
1292:
1286:
1282:
1276:Reticulate CM
1275:
1273:
1270:
1268:Nevus simplex
1267:
1266:
1264:
1260:
1257:
1253:
1250:
1248:
1244:
1234:
1231:
1229:
1226:
1225:
1223:
1219:
1213:
1210:
1209:
1207:
1203:
1197:
1194:
1192:
1189:
1186:
1184:
1181:
1178:
1176:
1173:
1172:
1170:
1166:
1163:
1161:
1157:
1153:
1146:
1141:
1139:
1134:
1132:
1127:
1126:
1123:
1110:
1106:
1105:
1101:
1099:
1095:
1094:
1090:
1087:
1086:
1082:
1081:
1078:
1073:
1069:
1053:
1049:
1044:
1039:
1034:
1029:
1025:
1021:
1017:
1010:
1003:
999:
996:
990:
983:
979:
976:
970:
968:
961:
960:
954:
950:
945:
940:
936:
932:
931:Radiographics
928:
921:
913:
909:
905:
901:
894:
886:
882:
878:
874:
870:
866:
862:
858:
851:
843:
839:
835:
831:
827:
823:
819:
815:
808:
806:
797:
793:
789:
785:
778:
770:
766:
761:
756:
751:
746:
742:
738:
734:
727:
725:
716:
712:
708:
704:
700:
696:
693:(10): 840β1.
692:
688:
681:
675:
670:
668:
666:
657:
653:
648:
643:
638:
633:
629:
625:
621:
614:
612:
610:
601:
597:
593:
589:
585:
581:
574:
566:
562:
558:
554:
550:
546:
543:(8): 521β30.
542:
538:
534:
527:
519:
513:
509:
502:
500:
498:
496:
494:
492:
484:
483:0-7216-2921-0
480:
476:
470:
468:
466:
464:
462:
460:
458:
449:
445:
441:
437:
433:
429:
425:
421:
414:
410:
402:
399:
395:
391:
374:
369:
365:
361:
354:
349:
345:
341:
334:
329:
328:
319:
318:
312:
309:
308:
305:
301:
297:
294:
291:
287:
283:
279:
275:
272:
268:
264:
260:
256:
252:
248:
244:
240:
236:
232:
229:
225:
222:
219:
218:
214:
211:
207:
203:
199:
196:
193:
189:
186:
183:
179:
176:
173:
169:
165:
164:
160:
159:
158:
145:
137:
135:
131:
127:
123:
119:
115:
111:
107:
103:
99:
95:
91:
87:
83:
73:
71:
67:
57:
51:
48:
46:
42:
38:
34:
30:
25:
20:
1842:Angiofibroma
1837:angiosarcoma
1792:
1772:Lymphangioma
1688:Microvenular
1602:Spindle cell
1565:
1548:Blood vessel
1228:Angiosarcoma
1102:
1091:
1083:
1023:
1019:
1009:
989:
957:
934:
930:
920:
906:(7): 671β3.
903:
899:
893:
863:(2): 164β7.
860:
856:
850:
820:(2): 100β3.
817:
813:
790:(9): 992β5.
787:
783:
777:
740:
737:Diagn Pathol
736:
690:
686:
680:
627:
623:
583:
579:
573:
540:
536:
526:
507:
474:
426:(1): 48β57.
423:
419:
413:
398:chemotherapy
394:radiotherapy
387:
295:
231:angiosarcoma
223:
215:
210:subcutaneous
202:angiosarcoma
197:
187:
182:angiosarcoma
177:
172:Sharon Weiss
161:
156:
143:
88:. They are
86:angiosarcoma
79:
65:
64:
1742:Angiolipoma
1710:Seriginosum
1683:Glomeruloid
1626:Venous lake
1581:Epithelioid
1088:: 9130-9133
857:Pathol. Int
687:Pathol. Int
360:endothelium
208:plaque, or
118:lymph nodes
1857:Categories
1737:of Mibelli
1668:Hemangioma
1586:Kaposiform
1104:DiseasesDB
630:: 531479.
405:References
344:hyalinized
290:metastasis
114:intestines
82:hemangioma
37:Micrograph
1764:Lymphatic
1678:Cavernous
1673:Capillary
1591:Infantile
1571:Composite
1417:In CM-AVM
1395:In CM-AVM
1353:Common VM
1221:Malignant
1026:(1): 12.
959:Full text
390:resection
384:Treatment
286:prognosis
228:low-grade
148:Diagnosis
45:Specialty
1596:Retiform
1429:Combined
1411:Sporadic
1389:Sporadic
1052:32765826
998:Archived
978:Archived
953:14615570
885:24778725
842:23809159
834:10197456
769:16859564
715:38650082
656:23607024
565:31168575
448:28749740
440:12502927
340:papillae
263:testicle
50:Oncology
1833:Angioma
1700:Angioma
1651:Classic
1098:D006390
1043:7394668
912:3839367
877:9589482
796:9302935
760:1555613
707:9788271
647:3626176
600:8827025
557:3740350
265:, deep
253:of the
212:nodule.
134:stomach
1826:Either
1794:PEComa
1720:Tufted
1715:Spider
1705:Cherry
1414:In HHT
1392:In HHT
1318:LM in
1255:Simple
1168:Benign
1050:
1040:
951:
910:
883:
875:
840:
832:
794:
767:
757:
743:: 12.
713:
705:
654:
644:
598:
563:
555:
514:
481:
446:
438:
396:, and
282:spleen
271:benign
267:muscle
239:tumors
206:dermal
122:pleura
100:, and
52:
1109:33472
1085:ICD-O
881:S2CID
838:S2CID
711:S2CID
561:S2CID
444:S2CID
346:cores
342:with
300:liver
251:tumor
140:Cause
98:liver
94:lungs
1093:MeSH
1048:PMID
949:PMID
908:PMID
873:PMID
830:PMID
792:PMID
765:PMID
703:PMID
652:PMID
628:2013
596:PMID
553:PMID
512:ISBN
479:ISBN
436:PMID
288:but
280:and
278:bone
257:and
255:skin
130:heel
110:neck
108:and
106:head
84:and
1038:PMC
1028:doi
939:doi
904:109
865:doi
822:doi
788:121
755:PMC
745:doi
695:doi
642:PMC
632:doi
588:doi
545:doi
428:doi
233:of
1859::
1107::
1096::
1046:.
1036:.
1024:10
1022:.
1018:.
966:^
947:.
935:23
933:.
929:.
902:.
879:.
871:.
861:48
859:.
836:.
828:.
818:28
816:.
804:^
786:.
763:.
753:.
739:.
735:.
723:^
709:.
701:.
691:48
689:.
664:^
650:.
640:.
626:.
622:.
608:^
594:.
584:20
582:.
559:.
551:.
541:10
539:.
535:.
490:^
456:^
442:.
434:.
424:27
422:.
392:,
276:,
136:.
132:,
128:,
124:,
120:,
116:,
112:,
96:,
1835:/
1774:/
1598:)
1532:e
1525:t
1518:v
1144:e
1137:t
1130:v
1077:D
1054:.
1030::
955:.
941::
914:.
887:.
867::
844:.
824::
798:.
771:.
747::
741:1
717:.
697::
658:.
634::
602:.
590::
567:.
547::
520:.
485:.
450:.
430::
323:1
321:Ξ±
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