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His successful research brought him to full professorship at
Cornell in 1929. From 1924 on his laboratory was located on the second floor of the new dairy science building, Stocking Hall (today home to Food Science), at Cornell where he did his Nobel Prize–winning research. In 1937 he succeeded in
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While hunting at age 17, Sumner was accidentally shot by a companion and as a result his left arm had to be amputated just below the elbow. He had been left-handed before the accident, after which he had to learn to do things with his right hand.
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Sumner married Cid
Ricketts (born Bertha Louise Ricketts in Brookhaven, Mississippi) when she attended medical school at Cornell. They married on July 10, 1915, and had four children. They were divorced in 1930, but she kept her married name.
452:. Sumner's work was unsuccessful for many years and many of his colleagues were doubtful, believing that what he was trying to achieve was impossible, but in 1926 he demonstrated that urease could be isolated and
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in 1946 for crystallization of enzymes. In 1947 Sumner became the director of
Cornell's enzyme chemistry laboratory. Sumner was elected to the
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and then chilling it; the chilled solution produced crystallized urease. He was also able to show by chemical tests that his pure urease was a
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in 1929. It had become clear that Sumner had devised a general crystallization method for enzymes, and also that all enzymes are proteins.
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In 1931 Sumner married Agnes
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553:"James Batcheller Sumner | Nobel Prize, Enzyme Crystallization & Protein Chemistry | Britannica"
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in pure form; a feat which had never been achieved before. The enzyme he worked with was
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See p.117: "It gave tests for protein and possessed a very high urease activity."
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429:. Cid Ricketts Sumner was murdered by their grandson, John R. Cutler, in 1970.
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Sumner died at age 67 of cancer in
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had obtained other crystalline enzymes by similar methods, starting with
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It was in 1917 at
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Both Sumner and
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682:"The Nobel Prize in Chemistry 1946 James B. Sumner - Biographical"
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603:"The Nobel Prize in Chemistry 1946 James B. Sumner - Facts"
397:. He then worked as assistant professor of biochemistry at
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Members of the United States
National Academy of Sciences
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went on to become an author, writing books that included
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Biographical
Memoirs of the National Academy of Sciences
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in 1910 where he was acquainted with prominent chemists
456:. He accomplished this by mixing purified urease with
299:(November 19, 1887 – August 12, 1955) was an American
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Fellows of the
American Academy of Arts and Sciences
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49:. Unsourced material may be challenged and removed.
319:. He was also the first to prove that enzymes are
523:in 1948. In 1949, he was elected a Fellow of the
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566:Harris, Ruth R.; Nirenberg, Marshall W. (1995).
778:including the Nobel Lecture, December 12, 1946
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729:The chemical nature of enzymes (Nobel lecture)
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468:isolating and crystallizing a second enzyme,
307:can be crystallized, for which he shared the
393:and obtained his Ph.D. degree in 1914 with
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648:. Infobase Publishing. pp. 354–355.
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331:Sumner was born on November 19, 1887, in
109:Learn how and when to remove this message
747:. American Academy of Arts and Sciences
742:"Book of Members, 1780–2010: Chapter S"
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218:First to show that an enzyme is a
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2527:People from Canton, Massachusetts
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719:website. Retrieved July 22, 2012.
717:Mississippi Artists and Musicians
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820:"Sumner, James B. (1887–1955)".
642:Carey, Charles W. (2014-05-14).
413:, which was made into the movie
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380:Worcester Polytechnic Institute
34:needs additional citations for
841:The Chemical Nature of Enzymes
780:The Chemical Nature of Enzymes
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577:. p. 41. Archived from
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496:and he spent five months in
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887:Nobel Prize in Chemistry
839:Sumner's Nobel Lecture
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492:In 1937, he was given a
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372:Mount Allison University
317:Wendell Meredith Stanley
309:Nobel Prize in Chemistry
258:Mount Allison University
230:Nobel Prize in Chemistry
2381:Percy Williams Bridgman
787:"Prof. James B. Sumner"
568:"The Harris Interviews"
500:working with Professor
297:James Batcheller Sumner
2415:Nobel Prize recipients
2392:Physiology or Medicine
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2180:M. Stanley Whittingham
1151:Hans von Euler-Chelpin
416:Tammy and the Bachelor
399:Cornell Medical School
391:Harvard Medical School
368:Charles Loring Jackson
342:Sumner graduated from
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1202:Frédéric Joliot-Curie
706:"Cid Ricketts Sumner"
494:Guggenheim Fellowship
478:Rockefeller Institute
333:Canton, Massachusetts
303:. He discovered that
157:Canton, Massachusetts
2307:John Howard Northrop
2224:Karl Barry Sharpless
1721:Dudley R. Herschbach
1546:Luis Federico Leloir
474:John Howard Northrop
313:John Howard Northrop
208:First to isolate an
43:improve this article
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2128:Jean-Pierre Sauvage
1865:Jens Christian Skou
1833:F. Sherwood Rowland
1745:Charles J. Pedersen
1709:Herbert A. Hauptman
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903:Jacobus van 't Hoff
803:1955Natur.176..859D
645:American Scientists
407:Cid Ricketts Sumner
364:James Bryant Conant
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1984:Richard R. Schrock
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1578:Ernst Otto Fischer
1502:Robert S. Mulliken
1438:Jaroslav HeyrovskĂ˝
1386:Hermann Staudinger
1206:Irène Joliot-Curie
772:on Nobelprize.org
711:2012-09-20 at the
411:Tammy Tell Me True
356:Farrington Daniels
344:Harvard University
263:Cornell University
199:Harvard University
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238:Scientific career
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758:
733:
721:
698:
686:Nobelprize.org
668:
654:
619:
607:Nobelprize.org
594:
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205:Known for
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175:(aged 67)
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137:Sumner in 1946
136:
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31:
29:
22:
15:
9:
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4:
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2:
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2370:
2363:
2360:
2357:
2354:
2353:
2351:
2349:
2345:
2339:(Switzerland)
2338:
2337:Hermann Hesse
2335:
2334:
2332:
2329:
2325:
2321:
2314:
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2277:
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2258:
2257:
2254:
2241:
2237:
2236:Louis E. Brus
2233:
2228:
2225:
2221:
2217:
2212:
2209:
2208:Benjamin List
2205:
2200:
2197:
2193:
2188:
2185:
2184:Akira Yoshino
2181:
2177:
2172:
2169:
2165:
2161:
2156:
2153:
2149:
2148:Joachim Frank
2145:
2140:
2137:
2133:
2129:
2124:
2121:
2117:
2113:
2112:Tomas Lindahl
2108:
2105:
2101:
2097:
2092:
2089:
2088:Arieh Warshel
2085:
2081:
2076:
2073:
2072:Brian Kobilka
2069:
2064:
2061:
2060:Dan Shechtman
2056:
2053:
2049:
2045:
2040:
2037:
2036:Ada E. Yonath
2033:
2029:
2024:
2021:
2017:
2013:
2008:
2005:
2000:
1997:
1992:
1989:
1985:
1981:
1976:
1973:
1969:
1968:Avram Hershko
1965:
1960:
1957:
1953:
1948:
1945:
1944:Kurt WĂĽthrich
1941:
1940:Koichi Tanaka
1937:
1932:
1929:
1925:
1921:
1916:
1915:
1913:
1909:
1902:
1898:
1894:
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1858:
1857:Paul D. Boyer
1853:
1850:
1846:
1842:
1837:
1834:
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1826:
1821:
1818:
1813:
1810:
1809:Michael Smith
1806:
1801:
1798:
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1785:
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1777:
1774:
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1769:Sidney Altman
1765:
1762:
1758:
1754:
1749:
1746:
1742:
1738:
1733:
1730:
1726:
1722:
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1714:
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1697:
1694:
1689:
1686:
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1678:
1674:
1673:Kenichi Fukui
1669:
1666:
1662:
1658:
1653:
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1646:
1641:
1638:
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1599:
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1579:
1574:
1571:
1570:William Stein
1567:
1563:
1558:
1555:
1550:
1547:
1542:
1539:
1535:
1530:
1527:
1522:
1519:
1518:George Porter
1515:
1511:
1510:Manfred Eigen
1506:
1503:
1498:
1495:
1490:
1487:
1482:
1479:
1475:
1470:
1467:
1463:
1458:
1455:
1454:Melvin Calvin
1450:
1447:
1446:Willard Libby
1442:
1439:
1434:
1431:
1426:
1423:
1418:
1415:
1411:
1406:
1403:
1398:
1395:
1394:Linus Pauling
1390:
1387:
1382:
1379:
1378:Richard Synge
1375:
1374:Archer Martin
1370:
1367:
1363:
1358:
1357:
1355:
1351:
1344:
1340:
1335:
1332:
1327:
1324:
1323:Arne Tiselius
1319:
1316:
1311:
1308:
1304:
1303:John Northrop
1300:
1295:
1292:
1287:
1284:
1279:
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1257:
1250:
1247:
1243:
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1223:
1218:
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1210:
1207:
1203:
1198:
1195:
1190:
1183:
1180:
1175:
1172:
1168:
1163:
1160:
1155:
1152:
1148:
1147:Arthur Harden
1143:
1140:
1139:Adolf Windaus
1135:
1132:
1127:
1124:
1119:
1118:
1116:
1112:
1096:
1091:
1084:
1081:
1076:
1073:
1072:Francis Aston
1068:
1065:
1060:
1057:
1052:
1045:
1042:
1037:
1030:
1023:
1020:
1015:
1012:
1007:
1004:
1003:Alfred Werner
999:
996:
995:Paul Sabatier
992:
987:
984:
979:
976:
971:
968:
963:
960:
955:
952:
947:
944:
943:Henri Moissan
939:
936:
931:
928:
923:
920:
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904:
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848:
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842:
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837:
827:
823:
818:
813:
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804:
800:
797:(4488): 859.
796:
792:
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776:
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743:
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714:
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655:9781438108070
651:
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584:on 2012-07-17
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506:Scheele Award
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311:in 1946 with
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99:February 2013
91:
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81:
77:
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70:
67:
63:
60: –
59:
55:
54:Find sources:
48:
44:
38:
37:
32:This article
30:
26:
21:
20:
2445:
2300:
2168:George Smith
2048:Akira Suzuki
2004:Gerhard Ertl
1988:Yves Chauvin
1936:John B. Fenn
1924:Ryoji Noyori
1911:2001–present
1885:Ahmed Zewail
1845:Harold Kroto
1829:Mario Molina
1757:Robert Huber
1729:John Polanyi
1713:Jerome Karle
1649:Georg Wittig
1534:Derek Barton
1526:Lars Onsager
1478:Giulio Natta
1474:Karl Ziegler
1466:John Kendrew
1298:
1234:Richard Kuhn
1159:Hans Fischer
975:Otto Wallach
911:Emil Fischer
825:
821:
794:
790:
779:
749:. Retrieved
736:
724:
716:
701:
689:. Retrieved
685:
659:. Retrieved
644:
610:. Retrieved
606:
597:
586:. Retrieved
579:the original
561:
547:
534:
514:
491:
466:
454:crystallized
439:
431:
424:
420:
414:
410:
403:
387:biochemistry
384:
341:
337:
330:
296:
295:
254:Institutions
248:Biochemistry
237:
214:crystallized
173:(1955-08-12)
105:
96:
86:
79:
72:
65:
53:
41:Please help
36:verification
33:
2497:1955 deaths
2492:1887 births
2284:Nobel Prize
2136:Ben Feringa
2120:Aziz Sancar
2100:Stefan Hell
2096:Eric Betzig
1873:Walter Kohn
1841:Robert Curl
1817:George Olah
1805:Kary Mullis
1781:Elias Corey
1773:Thomas Cech
1725:Yuan T. Lee
1693:Henry Taube
1226:Paul Karrer
1214:Peter Debye
1194:Harold Urey
1080:Fritz Pregl
1041:Fritz Haber
983:Marie Curie
517:Nobel Prize
352:Roger Adams
187:Nationality
2486:Categories
2324:Literature
1972:Irwin Rose
1952:Peter Agre
1877:John Pople
1685:Aaron Klug
1590:Paul Flory
1538:Odd Hassel
1462:Max Perutz
1343:Kurt Alder
1339:Otto Diels
1167:Carl Bosch
691:4 November
661:17 January
612:4 November
588:2012-07-23
539:References
450:jack beans
395:Otto Folin
301:biochemist
275:Otto Folin
149:1887-11-19
69:newspapers
2362:John Mott
2293:Chemistry
2286:laureates
1657:Paul Berg
1612:1976–2000
1353:1951–1975
1283:Otto Hahn
1114:1926–1950
894:1901–1925
883:Laureates
845:Sumner's
510:Stockholm
327:Biography
751:14 April
709:Archived
470:catalase
436:Research
321:proteins
190:American
2373:Physics
885:of the
799:Bibcode
476:of the
462:protein
458:acetone
442:enzymes
421:Quality
346:with a
305:enzymes
220:protein
83:scholar
2230:2023:
2214:2022:
2202:2021:
2190:2020:
2174:2019:
2158:2018:
2142:2017:
2126:2016:
2110:2015:
2094:2014:
2078:2013:
2066:2012:
2058:2011:
2042:2010:
2026:2009:
2010:2008:
2002:2007:
1994:2006:
1978:2005:
1962:2004:
1950:2003:
1934:2002:
1918:2001:
1891:2000:
1883:1999:
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1855:1997:
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1823:1995:
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1803:1993:
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1751:1988:
1735:1987:
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1707:1985:
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1627:1977:
1619:1976:
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1560:1972:
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1508:1967:
1500:1966:
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1484:1964:
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1400:1955:
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1384:1953:
1372:1952:
1360:1951:
1337:1950:
1329:1949:
1321:1948:
1313:1947:
1297:1946:
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1281:1944:
1273:1943:
1240:1939:
1232:1938:
1220:1937:
1212:1936:
1200:1935:
1192:1934:
1177:1932:
1165:1931:
1157:1930:
1145:1929:
1137:1928:
1129:1927:
1121:1926:
1093:1925:
1078:1923:
1070:1922:
1062:1921:
1054:1920:
1039:1918:
1017:1915:
1009:1914:
1001:1913:
989:1912:
981:1911:
973:1910:
965:1909:
957:1908:
949:1907:
941:1906:
933:1905:
925:1904:
917:1903:
909:1902:
901:1901:
791:Nature
652:
498:Sweden
482:pepsin
446:urease
419:, and
244:Fields
232:(1946)
226:Awards
210:enzyme
85:
78:
71:
64:
56:
2446:1946
2348:Peace
2282:1946
745:(PDF)
571:(PDF)
531:Death
426:Pinky
181:, USA
90:JSTOR
76:books
2471:1951
2466:1950
2461:1949
2456:1948
2451:1947
2441:1945
2436:1944
2431:1943
2426:1942
2421:1941
2328:1946
1267:1942
1260:1941
1253:1940
1186:1933
1087:1924
1048:1919
1033:1917
1026:1916
753:2011
693:2020
663:2016
650:ISBN
614:2020
366:and
315:and
216:form
168:Died
143:Born
62:news
807:doi
795:176
508:in
389:in
374:in
212:in
161:USA
45:by
2488::
2238:/
2234:/
2222:/
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2018:/
2014:/
1986:/
1982:/
1970:/
1966:/
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826:31
824:.
805:.
793:.
789:.
715:,
684:.
671:^
622:^
605:.
573:.
527:.
512:.
382:.
362:,
358:,
354:,
335:.
323:.
159:,
2330:)
2326:(
2275:e
2268:t
2261:v
875:e
868:t
861:v
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809::
801::
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695:.
665:.
616:.
591:.
555:.
260:,
151:)
147:(
112:)
106:(
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97:(
87:·
80:·
73:·
66:·
39:.
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