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Internal dosimetry

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each compartment is called Initial Deposition Fraction or IDF. It is a function of Activity Median Aerodynamic Diameter (AMAD), which includes size, shape, density, anatomical and physiological parameters as well as various conditions of exposure. The IDF values may be calculated either following the procedure described in ICRP 130/66 or obtaining it from their Annex. The general model of the HRTM is common to any element except the absorption rates {fr, ss, sr} which are related to the chemical form of the element. ICRP gives default values of absorption rates according to types F, M or S, but specific value for some compounds are available in ICRP 134 and ICRP 137.
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This model is applied for modeling the intake of radioactive aerosols by inhalation. The detailed description is given in ICRP 130 (2016) updating the ICRP 66 (1994). If a person inhales instantaneously a quantity I, it is deposited directly in some compartments of the HRTM. The fraction deposited in
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This is applied for modeling the intake of particles in the GI tract following the model provided ICRP 105 (ICRP 2005). Particles can be introduced in the GI Tract directly by ingestion, or from the RT. Deposition is in the stomach (ST). Part or all the flow is transferred, through SI, to the blood
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The ICRP further states "For internal exposure, committed effective doses are generally determined from an assessment of the intakes of radionuclides from bioassay measurements or other quantities (e.g., activity retained in the body or in daily excreta). The radiation dose is determined from the
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The ICRP models are used to simulate the distribution of the isotopes inside the human being. All current ICRP models, compiled in the OIR (ICRP134/137) data viewer, can be represented by compartmental systems with constant coefficients. The conceptual model used by ICRP can be summarized as it
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They are specific compartments to be applied for an element. Current models are described in ICRP 134 and ICRP 137. A few computer codes have been developed to estimate intake and calculate internal dose using biassay data.
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Internal dose monitoring of the radionuclides which emit radiation which can penetrate out of the body. For example X-rays, gamma rays of sufficient energy. It can be measured by devices such as a whole body counter.
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In a radioactive area, radionuclide particulate may be suspended in the air and can enter the body by inhalation. These particulates may be deposited in different parts of the respiratory tract depending upon their
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Monitoring of the radionuclides present in the body using the bio-assay sample taken out of the body; this includes samples of urine, sweat, feces, etc.
45: 308: 155:, LLNL, JAERI, thyroid and the knee phantoms. Some of the renowned mathematical phantoms are MIRD, CRISTY and nowadays voxel phantoms also known as 84:
is the integration time in years following the intake. The commitment period is taken to be 50 years for adults, and to age 70 years for children.
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data. Computer programs can be used for bioassay evaluations. The bioassay measurement values can be used to estimate unknown intake.
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Phoswich detectors with Be window and thin NaI(Tl)crystal and thick CsI(Tl)or CsI(Na), for low energy (<100 keV) photon detection
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Calibration of these systems is carried out with different type of physical and mathematical phantoms. Physical phantoms include
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The internal doses for workers or members of the public exposed to the intake of radioactive particulates can be estimated using
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HPGe detectors are replacing detectors for measuring the low energy and high energy photons with appropriate electronic systems.
709: 73:) as the sum of the products of the committed organ or tissue equivalent doses and the appropriate tissue weighting factors 779: 195:(B). The rate transfer from SI to B, is given by fA. The value of fA is associated to the element and their chemical form. 288: 673: 653: 378: 344: 232:- the measure of health effect due to low radiation doses. Also contains a description of the various dose quantities. 694: 476: 789: 759: 704: 699: 371: 156: 62:
The internal radiation dose due to injection, ingestion or inhalation radioactive substances is known as
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data such as lung and body counter measurements, urine or faecal radioisotope concentration, etc. The
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Radionuclides deposited within a body will irradiate tissues and organs and give rise to
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IRPA paper 54302 - Internal Dosimetry: The science and art of internal dose assessment
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International Commission on Radiological Protection. OIR Data Viewer; 2018-07-15.
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until they are excreted from the body or the radionuclide is completely decayed.
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Optimal design and mathematical model applied to establish bioassay programs
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Biokinetic modeling is widely used in internal dosimetry and to evaluate
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There are a few routes of intake (of radionuclide) namely,
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has a low background arrangement with counting systems
179:The human body can be divided into three systems: 46:
International Commission on Radiological Protection
142:NaI(Tl) detectors for high energy photon detection 771: 379: 88:intake using recommended dose coefficients". 69:The ICRP defines Committed effective dose, E( 545:Airborne radioactive particulate monitoring 16:Internal ionising radiation dose assessment 386: 372: 309:G. Sanchez Health Phys. 92(1):64–72(2007) 184:The human respiratory tract model (HRTM). 393: 192:The Human Alimentary Tract Model (HATM). 121: 206: 170: 772: 268:ICRP publication 103 - Paragraph 144. 710:Radiation Protection Convention, 1960 367: 30:incorporated inside the human body. 321:"Bioassay evaluations with Biokmod" 91: 22:is the science and art of internal 13: 14: 801: 352: 259:ICRP publication 103 - Glossary. 51: 477:Computed tomography dose index 338: 313: 302: 293: 282: 271: 262: 253: 242: 1: 236: 157:Computational human phantoms 7: 780:Nuclear safety and security 218: 10: 806: 741: 55: 739: 718: 687: 636: 600: 535: 452: 434:Radioactive contamination 401: 742:See also the categories 731:Radiation-induced cancer 726:Acute radiation syndrome 26:dose assessment due to 582:Semiconductor detector 538:measurement techniques 200:Systemic compartments. 601:Protection techniques 565:Scintillation counter 289:Whole Body Monitoring 122:Monitoring techniques 790:Radiation protection 760:Radiation protection 577:Radiation monitoring 570:Proportional counter 455:quantities and units 409:Background radiation 395:Radiation protection 278:Aerodynamic diameter 207:Bioassay evaluations 171:Biokinetic modelling 116:aerodynamic diameter 592:Whole-body counting 502:Mean glandular dose 439:Radioactive sources 163:In-vitro monitoring 429:Internal dosimetry 424:Ionizing radiation 136:whole body counter 127:In-vivo monitoring 24:ionising radiation 20:Internal dosimetry 767: 766: 748:Radiation effects 719:Radiation effects 482:Counts per minute 797: 785:Nuclear medicine 623:Radon mitigation 618:Potassium iodide 536:Instruments and 388: 381: 374: 365: 364: 347: 342: 336: 335: 333: 332: 323:. Archived from 317: 311: 306: 300: 297: 291: 286: 280: 275: 269: 266: 260: 257: 251: 246: 92:Routes of intake 805: 804: 800: 799: 798: 796: 795: 794: 770: 769: 768: 763: 762: 744:Medical physics 735: 714: 683: 632: 596: 537: 531: 492:Equivalent dose 454: 448: 397: 392: 355: 350: 343: 339: 330: 328: 319: 318: 314: 307: 303: 298: 294: 287: 283: 276: 272: 267: 263: 258: 254: 247: 243: 239: 221: 209: 173: 166: 165: 150: 129: 124: 94: 79: 60: 54: 17: 12: 11: 5: 803: 793: 792: 787: 782: 765: 764: 740: 737: 736: 734: 733: 728: 722: 720: 716: 715: 713: 712: 707: 702: 697: 691: 689: 685: 684: 682: 681: 676: 671: 666: 661: 656: 651: 646: 640: 638: 634: 633: 631: 630: 625: 620: 615: 610: 608:Lead shielding 604: 602: 598: 597: 595: 594: 589: 584: 579: 573: 572: 567: 562: 557: 555:Geiger counter 552: 547: 541: 539: 533: 532: 530: 529: 524: 519: 514: 509: 504: 499: 494: 489: 487:Effective dose 484: 479: 474: 472:Committed dose 469: 464: 458: 456: 450: 449: 447: 446: 441: 436: 431: 426: 421: 419:Health physics 416: 411: 405: 403: 399: 398: 391: 390: 383: 376: 368: 362: 361: 354: 353:External links 351: 349: 348: 337: 312: 301: 292: 281: 270: 261: 252: 240: 238: 235: 234: 233: 227: 225:Committed dose 220: 217: 208: 205: 172: 169: 147: 146: 143: 123: 120: 111: 110: 107: 104: 101: 93: 90: 77: 64:committed dose 58:committed dose 56:Main article: 53: 52:Committed dose 50: 35:committed dose 15: 9: 6: 4: 3: 2: 802: 791: 788: 786: 783: 781: 778: 777: 775: 761: 757: 753: 752:Radioactivity 749: 745: 738: 732: 729: 727: 724: 723: 721: 717: 711: 708: 706: 703: 701: 698: 696: 693: 692: 690: 686: 680: 677: 675: 672: 670: 667: 665: 662: 660: 657: 655: 652: 650: 647: 645: 642: 641: 639: 637:Organisations 635: 629: 626: 624: 621: 619: 616: 614: 611: 609: 606: 605: 603: 599: 593: 590: 588: 585: 583: 580: 578: 575: 574: 571: 568: 566: 563: 561: 558: 556: 553: 551: 548: 546: 543: 542: 540: 534: 528: 525: 523: 520: 518: 515: 513: 510: 508: 505: 503: 500: 498: 495: 493: 490: 488: 485: 483: 480: 478: 475: 473: 470: 468: 465: 463: 462:Absorbed dose 460: 459: 457: 451: 445: 442: 440: 437: 435: 432: 430: 427: 425: 422: 420: 417: 415: 412: 410: 407: 406: 404: 402:Main articles 400: 396: 389: 384: 382: 377: 375: 370: 369: 366: 360: 357: 356: 346: 341: 327:on 2016-12-20 326: 322: 316: 310: 305: 296: 290: 285: 279: 274: 265: 256: 249: 245: 241: 231: 228: 226: 223: 222: 216: 214: 204: 201: 196: 193: 188: 185: 180: 177: 168: 164: 160: 158: 154: 144: 141: 140: 139: 137: 132: 128: 119: 117: 108: 105: 102: 99: 98: 97: 89: 85: 83: 76: 72: 67: 65: 59: 49: 47: 43: 38: 36: 31: 29: 28:radionuclides 25: 21: 756:Radiobiology 587:Survey meter 507:Monitor unit 453:Measurement 444:Radiobiology 428: 359:ICRP website 340: 329:. Retrieved 325:the original 315: 304: 295: 284: 273: 264: 255: 244: 210: 199: 197: 191: 189: 183: 181: 178: 174: 162: 161: 148: 133: 126: 125: 112: 95: 86: 81: 74: 70: 68: 61: 39: 32: 19: 18: 628:Respirators 560:Ion chamber 774:Categories 688:Regulation 331:2016-12-13 237:References 109:Absorption 100:Inhalation 700:NRC (USA) 649:HPS (USA) 550:Dosimeter 467:Becquerel 414:Dosimetry 176:follows. 106:Injection 103:Ingestion 705:ONR (UK) 695:IRR (UK) 674:SRP (UK) 613:Glovebox 517:Roentgen 219:See also 213:bioassay 80:, where 42:bioassay 679:UNSCEAR 644:Euratom 527:Sievert 230:Sievert 758:, and 153:BOMAB 669:IRPA 664:ICRP 659:ICRU 654:IAEA 497:Gray 522:Rem 512:Rad 198:c) 190:b) 182:a) 776:: 754:, 750:, 746:, 159:. 134:A 118:. 66:. 387:e 380:t 373:v 334:. 82:t 78:T 75:W 71:t

Index

ionising radiation
radionuclides
committed dose
bioassay
International Commission on Radiological Protection
committed dose
committed dose
aerodynamic diameter
whole body counter
BOMAB
Computational human phantoms
bioassay
Committed dose
Sievert

Aerodynamic diameter
Whole Body Monitoring
G. Sanchez Health Phys. 92(1):64–72(2007)
"Bioassay evaluations with Biokmod"
the original
Optimal design and mathematical model applied to establish bioassay programs
ICRP website
v
t
e
Radiation protection
Background radiation
Dosimetry
Health physics
Ionizing radiation

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