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Indium-111

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Octreotide is an somatostatin receptor inhibitor pharmaceutical which binds with high affinity to somatostatin receptors 2 and 5, interfering with normal receptor function. It is used as a drug to treat several neuroendocrine tumors in which somatostatin receptors are overexpressed or overactive.
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Takács, S.; Tárkányi, F.; Hermanne, A. (Dec 2005). "Validation and upgrading of the recommended cross-section data of charged particle reactions: Gamma emitter radioisotopes".
651: 259:, or other molecular targeted proteins or other molecules, typically using a chelate to bind the radionuclide (in this case In) to the targeting molecule during the 1338: 644: 1359: 1298: 427: 1453: 236: 601: 508: 637: 861: 342:
imaging can identify the presence, levels of somatostatin receptor 2,5 expression, extent of disease and response to therapy
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targeted molecules or cells. During its radioactive decay, it emits low energy gamma (γ) photons which can be imaged using
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In can also be formulated in the chemical form In oxyquinoline (oxine) for labeling blood cells and components
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Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms
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with a half-life of 2.8 days. Indium-111 chloride (InCl) solution is produced by proton irradiation of a
576: 1035: 1673: 1374: 1170: 1077: 903: 220:. The former method is more commonly used as it results in a high level of radionuclide purity. 674: 1308: 1235: 446: 1428: 1354: 1349: 1268: 913: 775: 608: 542: 8: 629: 546: 491: 1419: 1293: 1288: 1153: 1137: 1106: 1072: 876: 839: 729: 402: 264: 171: 1394: 1283: 1278: 1230: 1200: 725: 705: 661: 558: 436: 187: 175: 96: 91: 84: 30: 812: 715: 710: 700: 550: 487: 377: 339: 324: 301: 224: 198: 160: 40: 1167: 1087: 740: 385: 594: 1630: 1516: 1116: 989: 946: 884: 857: 793: 748: 682: 554: 381: 260: 202: 67: 1662: 1333: 1256: 1183: 562: 373: 305: 228: 125: 50: 1648: 1635: 1620: 1521: 1506: 1457: 1364: 1303: 1148: 934: 665: 471:
Wang, M.; Audi, G.; Kondev, F. G.; Huang, W. J.; Naimi, S.; Xu, X. (2017).
365: 240: 232: 151: 147: 1625: 1615: 1605: 1600: 1565: 1550: 1511: 1501: 1466: 1424: 1323: 1251: 1205: 1067: 909: 852: 824: 721: 473:"The AME2016 atomic mass evaluation (II). Tables, graphs, and references" 205: 130: 1595: 1590: 1585: 1575: 1570: 1496: 1491: 1486: 1476: 1434: 1379: 1344: 1327: 1318: 1273: 1240: 1225: 1220: 1133: 1129: 1124: 1061: 1054: 1048: 1041: 1028: 971: 919: 771: 696: 313: 309: 277: 252: 142: 1640: 1610: 1560: 1555: 1545: 1526: 1471: 1445: 1409: 1263: 1245: 1189: 1179: 1094: 938: 847: 781: 389: 369: 354: 213: 103: 1163: 358: 333:
Medullary thyroid cancer, pituitary adenoma, small cell lung cancer
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Ibritumomab Tiuxetan; Zevalin - For dosimetry estimates prior to
256: 209: 190: 1449: 1399: 1384: 828: 435:. Bureau international des poids et mesures. 2006. p. 75. 194: 1413: 1369: 981: 763: 509:"FDA Label Document:Indium In-111 Chloride Sterile Solution" 251:
When formulated as an InCl solution, it can be used to bind
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Gastroenteropancreatic (GEP) tumors: carcinoid, insulinoma
659: 532: 239:(SPECT) gamma cameras (primary energies (ε) of 171.3 470: 267:process, which is tailored to the desired product. 1660: 327:, neuroblastoma, ganglioneuroma, paraganglioma 645: 270: 246: 652: 638: 290:— PSMA antibody imaging of prostate cancer 237:single-photon emission computed tomography 464: 294: 218:International Atomic Energy Agency (IAEA) 1661: 1649:Therapeutic radiopharmaceuticals (V10) 607:. Nordion(Canada), Inc. Archived from 633: 503: 501: 13: 212:target (Cd(p,2n) or Cd(p,n)) in a 14: 1685: 498: 388:infections and determination of 364:Leukocytes for localization of 323:Sympathoadrenal system tumors: 223:Indium-111 is commonly used in 569: 526: 429:Table of Radionuclides, Vol. 3 420: 1: 577:"PubChem In-111 Oxyquinoline" 492:10.1088/1674-1137/41/3/030003 413: 306:diethylenetriaminopentaacetic 408:Indium white blood cell scan 7: 396: 243:(91%) and 245.4 keV (94%)) 10: 1690: 555:10.1016/j.nimb.2005.06.209 486:(3): 030003-1–030003-442. 176:Complete table of nuclides 1539: 1444: 1162: 1147: 1115: 980: 933: 875: 838: 811: 762: 739: 673: 170: 158: 141: 136: 124: 102: 90: 83: 66: 49: 45:indium-111, 111In, In-111 39: 29: 24: 581:pubchem.ncbi.nlm.nih.gov 247:Uses in nuclear medicine 1375:Gallium (Ga) gozetotide 924:Iodinated human albumin 675:Central nervous system 513:www.accessdata.fda.gov 227:diagnostic imaging by 1309:Fludeoxyglucose (18F) 1236:Pittsburgh compound B 877:Cardiovascular system 372:, detect and monitor 271:In labeled antibodies 1355:Fluorothymidine F-18 1350:Fluoroestradiol F-18 1269:Desmethoxyfallypride 776:Sodium iodohippurate 662:radiopharmaceuticals 216:, as recommended by 1339:Fluorodeoxysorbitol 1083:Fluoroethyltyrosine 1022:Satumomab pendetide 602:"IN-111 FACT SHEET" 547:2005NIMPB.240..790T 295:In labeled peptides 197:(In). It decays by 21: 20:Indium-111, In 1669:Isotopes of indium 1420:Piflufolastat F-18 1294:Flotufolastat F-18 1289:Flortaucipir (18F) 1107:Piflufolastat F-18 1078:Fluorodeoxyglucose 1017:Capromab pendetide 840:Respiratory system 730:Flutemetamol (18F) 614:on 3 December 2011 452:on 20 October 2016 403:Isotopes of indium 320:Examples include: 304:(including in In ( 280:immunotherapy for 172:Isotopes of indium 19: 1656: 1655: 1535: 1534: 1429:Rubidium chloride 1395:N-Methylspiperone 1284:Florbetapir (18F) 1279:Florbetaben (18F) 1231:N-Methylspiperone 1062:Iobenguane (131I) 1049:Iobenguane (123I) 914:Rubidium chloride 726:Florbetapir (18F) 706:Iofetamine (123I) 480:Chinese Physics C 378:mycotic aneurysms 181: 180: 92:Natural abundance 16:Isotope of indium 1681: 1674:Medical isotopes 1160: 1159: 1059: 1046: 1033: 1005:Hynic-octreotide 813:Gastrointestinal 711:Iolopride (123I) 701:Ioflupane (123I) 654: 647: 640: 631: 630: 624: 623: 621: 619: 613: 606: 598: 592: 591: 589: 587: 573: 567: 566: 530: 524: 523: 521: 519: 505: 496: 495: 477: 468: 462: 461: 459: 457: 451: 445:. Archived from 434: 424: 325:pheochromocytoma 225:nuclear medicine 199:electron capture 163: 120: 115: 76: 59: 22: 18: 1689: 1688: 1684: 1683: 1682: 1680: 1679: 1678: 1659: 1658: 1657: 1652: 1651: 1645: 1541:Isotopes used: 1531: 1440: 1151: 1143: 1138:Iodocholesterol 1111: 1088:Sodium fluoride 1057: 1044: 1031: 976: 929: 871: 834: 807: 758: 741:Skeletal system 735: 669: 658: 628: 627: 617: 615: 611: 604: 600: 599: 595: 585: 583: 575: 574: 570: 531: 527: 517: 515: 507: 506: 499: 475: 469: 465: 455: 453: 449: 443: 432: 426: 425: 421: 416: 399: 297: 273: 249: 174: 159: 118: 113: 106: 70: 53: 17: 12: 11: 5: 1687: 1677: 1676: 1671: 1654: 1653: 1646: 1644: 1643: 1638: 1633: 1631:technetium-99m 1628: 1623: 1618: 1613: 1608: 1603: 1598: 1593: 1588: 1583: 1578: 1573: 1568: 1563: 1558: 1553: 1548: 1542: 1540: 1537: 1536: 1533: 1532: 1530: 1529: 1524: 1519: 1514: 1509: 1504: 1499: 1494: 1489: 1484: 1479: 1474: 1469: 1463: 1461: 1442: 1441: 1439: 1438: 1432: 1422: 1417: 1407: 1402: 1397: 1392: 1387: 1382: 1377: 1372: 1367: 1362: 1357: 1352: 1347: 1342: 1336: 1331: 1321: 1316: 1306: 1301: 1296: 1291: 1286: 1281: 1276: 1271: 1266: 1261: 1260: 1259: 1249: 1243: 1238: 1233: 1228: 1223: 1218: 1213: 1208: 1203: 1198: 1193: 1187: 1176: 1174: 1157: 1145: 1144: 1142: 1141: 1127: 1121: 1119: 1117:Adrenal cortex 1113: 1112: 1110: 1109: 1104: 1103: 1102: 1092: 1091: 1090: 1085: 1080: 1075: 1065: 1052: 1039: 1026: 1025: 1024: 1019: 1009: 1008: 1007: 1002: 997: 986: 984: 978: 977: 975: 974: 969: 964: 958: 953: 943: 941: 931: 930: 928: 927: 917: 907: 897: 891: 881: 879: 873: 872: 870: 869: 855: 850: 844: 842: 836: 835: 833: 832: 821: 819: 809: 808: 806: 805: 791: 790: 789: 779: 768: 766: 760: 759: 757: 756: 745: 743: 737: 736: 734: 733: 719: 713: 708: 703: 694: 679: 677: 671: 670: 657: 656: 649: 642: 634: 626: 625: 593: 568: 541:(4): 790–802. 525: 497: 463: 441: 418: 417: 415: 412: 411: 410: 405: 398: 395: 394: 393: 382:vascular graft 362: 348: 347: 345: 344: 343: 336: 335: 334: 331: 328: 296: 293: 292: 291: 284: 272: 269: 261:radiosynthesis 248: 245: 179: 178: 168: 167: 164: 156: 155: 145: 139: 138: 134: 133: 128: 126:Decay products 122: 121: 116: 111: 100: 99: 94: 88: 87: 81: 80: 77: 64: 63: 60: 47: 46: 43: 37: 36: 33: 27: 26: 15: 9: 6: 4: 3: 2: 1686: 1675: 1672: 1670: 1667: 1666: 1664: 1650: 1642: 1639: 1637: 1634: 1632: 1629: 1627: 1624: 1622: 1619: 1617: 1614: 1612: 1609: 1607: 1604: 1602: 1599: 1597: 1594: 1592: 1589: 1587: 1584: 1582: 1579: 1577: 1574: 1572: 1569: 1567: 1564: 1562: 1559: 1557: 1554: 1552: 1549: 1547: 1544: 1543: 1538: 1528: 1525: 1523: 1520: 1518: 1515: 1513: 1510: 1508: 1505: 1503: 1500: 1498: 1495: 1493: 1490: 1488: 1485: 1483: 1480: 1478: 1475: 1473: 1470: 1468: 1465: 1464: 1462: 1459: 1455: 1451: 1447: 1443: 1436: 1433: 1430: 1426: 1423: 1421: 1418: 1415: 1411: 1408: 1406: 1403: 1401: 1398: 1396: 1393: 1391: 1388: 1386: 1383: 1381: 1378: 1376: 1373: 1371: 1368: 1366: 1363: 1361: 1358: 1356: 1353: 1351: 1348: 1346: 1343: 1340: 1337: 1335: 1334:Fluorocholine 1332: 1329: 1325: 1322: 1320: 1317: 1314: 1310: 1307: 1305: 1302: 1300: 1297: 1295: 1292: 1290: 1287: 1285: 1282: 1280: 1277: 1275: 1272: 1270: 1267: 1265: 1262: 1258: 1255: 1254: 1253: 1250: 1247: 1244: 1242: 1239: 1237: 1234: 1232: 1229: 1227: 1224: 1222: 1219: 1217: 1214: 1212: 1209: 1207: 1204: 1202: 1199: 1197: 1194: 1191: 1188: 1185: 1181: 1178: 1177: 1175: 1172: 1169: 1165: 1161: 1158: 1155: 1150: 1149:Radionuclides 1146: 1139: 1135: 1131: 1128: 1126: 1123: 1122: 1120: 1118: 1114: 1108: 1105: 1101: 1098: 1097: 1096: 1093: 1089: 1086: 1084: 1081: 1079: 1076: 1074: 1071: 1070: 1069: 1066: 1063: 1056: 1053: 1050: 1043: 1040: 1037: 1030: 1027: 1023: 1020: 1018: 1015: 1014: 1013: 1010: 1006: 1003: 1001: 998: 996: 993: 992: 991: 988: 987: 985: 983: 979: 973: 970: 968: 965: 962: 959: 957: 954: 952: 948: 945: 944: 942: 940: 936: 932: 925: 921: 918: 915: 911: 908: 905: 901: 898: 895: 892: 890: 886: 883: 882: 880: 878: 874: 867: 866:Pentetic acid 863: 859: 856: 854: 851: 849: 846: 845: 843: 841: 837: 830: 826: 823: 822: 820: 818: 814: 810: 803: 802:Pentetic acid 799: 795: 792: 788: 785: 784: 783: 780: 777: 773: 770: 769: 767: 765: 761: 754: 753:Medronic acid 750: 747: 746: 744: 742: 738: 731: 727: 723: 720: 717: 714: 712: 709: 707: 704: 702: 698: 695: 692: 691:Pentetic acid 688: 684: 681: 680: 678: 676: 672: 667: 663: 655: 650: 648: 643: 641: 636: 635: 632: 610: 603: 597: 582: 578: 572: 564: 560: 556: 552: 548: 544: 540: 536: 529: 514: 510: 504: 502: 493: 489: 485: 481: 474: 467: 448: 444: 442:92-822-2218-7 438: 431: 430: 423: 419: 409: 406: 404: 401: 400: 391: 387: 383: 379: 376:, and detect 375: 374:osteomyelitis 371: 367: 363: 360: 356: 353: 352: 351: 346: 341: 340:pentetreotide 337: 332: 329: 326: 322: 321: 318: 317: 315: 311: 307: 303: 302:pentetreotide 299: 298: 289: 285: 283: 279: 275: 274: 268: 266: 265:radiolabeling 262: 258: 254: 244: 242: 238: 234: 230: 229:radiolabeling 226: 221: 219: 215: 211: 207: 204: 200: 196: 192: 189: 185: 177: 173: 169: 165: 162: 157: 153: 149: 146: 144: 140: 135: 132: 129: 127: 123: 119:2.8049 d 117: 110: 105: 101: 98: 95: 93: 89: 86: 82: 78: 74: 69: 65: 61: 57: 52: 48: 44: 42: 38: 34: 32: 28: 23: 1636:thallium-201 1621:samarium-153 1580: 1481: 1458:scintigraphy 1365:Flutemetamol 1304:Fluciclovine 1073:Fluciclovine 1036:Minretumomab 1011: 966: 935:Inflammation 899: 618:23 September 616:. Retrieved 609:the original 596: 584:. Retrieved 580: 571: 538: 534: 528: 516:. Retrieved 512: 483: 479: 466: 454:. Retrieved 447:the original 428: 422: 366:inflammation 349: 250: 222: 183: 182: 148:Decay energy 108: 85:Nuclide data 72: 55: 1626:selenium-75 1616:rubidium-82 1606:nitrogen-13 1601:krypton-81m 1566:fluorine-18 1551:chromium-51 1206:Carfentanil 1152:(including 995:Arcitumomab 961:Tilmanocept 951:Exametazime 894:Tetrofosmin 687:Exametazime 660:Diagnostic 288:ProstaScint 206:cadmium-111 188:radioactive 137:Decay modes 1663:Categories 1647:See also: 1596:iodine-131 1591:iodine-125 1586:iodine-123 1581:indium-111 1576:gallium-68 1571:gallium-67 1435:Setoperone 1360:Fluspidine 1345:Fluorodopa 1328:Altanserin 1319:Flumazenil 1274:Fallypride 1241:Raclopride 1226:Methionine 1221:Flumazenil 1192:(Cimbi-36) 798:Mertiatide 414:References 314:Octreoscan 310:octreotide 253:antibodies 186:(In) is a 184:Indium-111 143:Decay mode 1641:xenon-133 1611:oxygen-15 1561:copper-64 1556:cobalt-57 1546:carbon-11 1446:gamma ray 1299:Flubatine 1246:Verapamil 1190:25B-NBOMe 1184:ME@HAPTHI 1000:Votumumab 956:Sulesomab 939:infection 904:Imciromab 889:Sestamibi 716:Iomazenil 563:0168-583X 392:kinetics; 390:leukocyte 370:abscesses 361:detection 355:Platelets 214:cyclotron 104:Half-life 1315:analogue 1164:positron 1100:Dotatate 397:See also 359:thrombus 282:lymphoma 257:peptides 68:Neutrons 1313:glucose 1257:Ammonia 1201:Choline 1196:Acetate 1154:tracers 817:Hepatic 543:Bibcode 456:26 June 308:(DTPA)- 210:cadmium 191:isotope 51:Protons 25:General 1450:photon 1400:Nifene 1385:Mefway 1311:(FDG)- 1058:  1045:  1032:  862:Tc-MAA 829:SeHCAT 586:20 Aug 561:  518:20 Aug 439:  312:) and 233:planar 203:stable 195:indium 31:Symbol 1454:SPECT 1414:Water 1370:FMISO 1341:(FDS) 982:Tumor 764:Renal 612:(PDF) 605:(PDF) 476:(PDF) 450:(PDF) 433:(PDF) 386:shunt 166:0.860 41:Names 1390:MPPF 1216:DTBZ 1211:DASB 1171:list 787:ETS2 620:2012 588:2018 559:ISSN 520:2018 458:2017 437:ISBN 384:and 368:and 357:for 1405:FET 1168:PET 666:V09 551:doi 539:240 488:doi 338:In 300:In 286:In 241:keV 235:or 201:to 193:of 152:MeV 112:1/2 97:syn 1665:: 1527:Xe 1522:Tl 1517:Tc 1512:Se 1507:Sm 1502:Kr 1482:In 1477:Ga 1472:Co 1467:Cr 1425:Rb 1380:Ga 1264:Cu 1132:/ 1095:Cu 1012:In 990:Tc 972:Ga 967:In 947:Tc 910:Rb 900:In 885:Tc 864:, 858:Tc 853:Kr 848:Xe 825:Se 800:, 794:Tc 782:Cu 749:Tc 728:, 689:, 683:Tc 579:. 557:. 549:. 537:. 511:. 500:^ 484:41 482:. 478:. 380:, 316:) 263:/ 255:, 161:EC 131:Cd 79:62 62:49 35:In 1497:I 1492:I 1487:I 1460:) 1456:/ 1452:( 1448:/ 1437:) 1431:) 1427:( 1416:) 1412:( 1410:O 1330:) 1326:( 1324:F 1252:N 1248:) 1186:) 1182:( 1180:C 1173:) 1166:( 1156:) 1140:) 1136:( 1134:I 1130:I 1125:I 1068:F 1064:) 1060:( 1055:I 1051:) 1047:( 1042:I 1038:) 1034:( 1029:I 963:) 949:( 937:/ 926:) 922:( 920:I 916:) 912:( 906:) 902:( 896:) 887:( 868:) 860:( 831:) 827:( 815:/ 804:) 796:( 778:) 774:( 772:I 755:) 751:( 732:) 724:( 722:F 718:) 699:( 697:I 693:) 685:( 668:) 664:( 653:e 646:t 639:v 622:. 590:. 565:. 553:: 545:: 522:. 494:. 490:: 460:. 278:Y 154:) 150:( 114:) 109:t 107:( 75:) 73:N 71:( 58:) 56:Z 54:(

Index

Symbol
Names
Protons
Neutrons
Nuclide data
Natural abundance
syn
Half-life
Decay products
Cd
Decay mode
Decay energy
MeV
EC
Isotopes of indium
Complete table of nuclides
radioactive
isotope
indium
electron capture
stable
cadmium-111
cadmium
cyclotron
International Atomic Energy Agency (IAEA)
nuclear medicine
radiolabeling
planar
single-photon emission computed tomography
keV

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