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Hypertensive disease of pregnancy

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7-day interval) or 0.3 g in a 24-h period. Like ordinary pre-eclampsia, superimposed pre-eclampsia can also occur with severe features, which are defined as: systolic blood pressure ≥160 mmHg or diastolic blood pressure ≥110 mmHg despite escalation of antihypertensive therapy; thrombocytopenia (platelet count <100,000/microL); impaired liver function; new-onset or worsening renal insufficiency; pulmonary edema; or persistent cerebral or visual disturbances. As a result, superimposed pre-eclampsia can be diagnosed without proteinuria when a sudden increase in previously well-controlled blood pressure is accompanied by severe features of pre-eclampsia.
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primary, and thus classified as essential hypertension, secondary causes such as renal, vascular, and endocrine disorders must also be considered, especially in patients with chronic hypertension presenting abnormally, for instance at a young age or refractory to first-line treatment. If end-organ damage or an underlying cause of hypertension is identified, these conditions must also be treated. Women with chronic hypertension in pregnancy must be closely monitored because they are five times as likely as those with normal blood pressure to develop pre-eclampsia, which is a much more severe condition with serious risks for the mother and fetus.
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persisting at least 12 weeks after giving birth. However, there is some controversy over the utility of adopting lower thresholds for diagnosis of chronic hypertension, which is more consistent with recent recommendations from the American College of Cardiology and the American Heart Association for the diagnosis of hypertension in adults. Chronic hypertension in pregnancy is now considered mild if blood pressures do not exceed 159 mmHg systolic and 109 mmHg diastolic and severe if pressures are ≥ 160 mmHg systolic or 110 mmHg diastolic, although controversy also exists as to the most appropriate cutoffs for this definition.
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where preeclampsia occurs more frequently. For example, in 1998 birth rates among women ages 30 to 44 and the number of births to women ages 45 and older were at the highest levels in three decades, according to the National Center for Health Statistics. Furthermore, between 1980 and 1998, rates of twin births increased about 50 percent overall and 1,000 percent among women ages 45 to 49; rates of triplet and other higher-order multiple births jumped more than 400 percent overall, and 1,000 percent among women in their 40s.
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given the increased risk of medical complications immediately following delivery of the fetus. A recent systematic review found that postpartum home blood pressure monitoring likely improves the determination of blood pressure measures and overall patient of these conditions. Additionally, home blood
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Pregnant women with chronic hypertension diagnosed before or early in pregnancy should be evaluated to identify the underlying cause of hypertension as well as possible existing end-organ damage caused by hypertension, such as cardiac and kidney injury. Although most cases of chronic hypertension are
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Preeclampsia superimposed on chronic hypertension occurs when a pregnant woman with chronic hypertension develops signs of pre-eclampsia, typically defined as new onset of proteinuria ≥30 mg/dL (1+ in the dipstick) in at least 2 random urine specimens that were collected ≥4 h apart (but within a
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The effects of high blood pressure during pregnancy vary depending on the disorder and other factors. Preeclampsia does not in general increase a woman's risk for developing chronic hypertension or other heart-related problems. Women with normal blood pressure who develop preeclampsia after the 20th
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The diagnostic criteria for chronic hypertension are typically considered to be at least two separate blood pressure readings taken at least four hours apart with systolic blood pressure ≥ 140mmHg, diastolic blood pressure ≥90 mmHg, or both, identified before pregnancy, before 20 weeks gestation, or
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All of these sensations can be caused by other disorders; they can also occur in healthy pregnancies. Regular visits are scheduled to track blood pressure and level of protein in urine, to order and analyze blood tests that detect signs of preeclampsia, and to monitor fetal development more closely.
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Although the proportion of pregnancies with gestational hypertension and eclampsia has remained about the same in the U.S. over the past decade, the rate of preeclampsia has increased by nearly one-third. This increase is due in part to a rise in the numbers of older mothers and of multiple births,
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is a provisional diagnosis that involves newly increased blood pressure in a pregnant woman that usually develops after 20 weeks of gestation, but does not currently show any signs of proteinuria or other features associated with preeclampsia. Up to 50% of gestational hypertension patients go on to
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Because chronic hypertension can progress to more severe forms of disease, it is important to accurately diagnose the condition early, ideally prior to pregnancy, and initiate management to control parental blood pressure. This is often difficult, as many reproductive individuals may not regularly
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Even though high blood pressure and related disorders during pregnancy can be serious, most women with high blood pressure and those who develop preeclampsia have successful pregnancies. Obtaining early and regular prenatal care for pregnant women is important to identify and treat blood pressure
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Although many pregnant women with high blood pressure have healthy babies without serious problems, high blood pressure can be dangerous for both the mother and baby. Women with pre-existing, or chronic, high blood pressure are more likely to have certain complications during pregnancy than those
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Blood pressure control can be accomplished before pregnancy. Medications can control blood pressure. Certain medications may not be ideal for blood pressure control during pregnancy such as angiotensin-converting enzyme (ACE) inhibitors and angiotensin II (AII) receptor antagonists. Controlling
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Chronic hypertension is a type of high blood pressure in a pregnant woman that is pre-existing before conception, diagnosed early in pregnancy, or persists significantly after the end of pregnancy. It affects about 5% of all pregnancies and can be a primary disorder of essential hypertension or
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Chronic poorly-controlled high blood pressure before and during pregnancy puts a pregnant woman and her baby at risk for problems. It is associated with an increased risk for maternal complications such as preeclampsia, placental abruption (when the placenta separates from the wall of the
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The only way to definitively treat a hypertensive disease of pregnancy (i.e. preeclampsia/eclampsia, gestational hypertension, etc. ) is to deliver the fetus. This prevents further development of complications related to the disorder in both the mother and the fetus. Therefore, the first line
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For all hypertensive disorders of pregnancy, a major component of care is management of the associated hypertension. This involves use of antihypertensive medication as well as restricting activity to lower blood pressure to reduce the risk of stroke. In women with preeclampsia or eclampsia,
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There is no single test to predict or diagnose preeclampsia. Key signs are increased blood pressure and protein in the urine (proteinuria). Other symptoms that seem to occur with preeclampsia include persistent headaches, blurred vision or sensitivity to light, and abdominal pain.
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Maternal hypertensive disorders occurred in about 20.7 million women in 2013. About 10% of pregnancies globally are complicated by hypertensive diseases. In the United States, hypertensive disease of pregnancy affects about 8% to 13% of pregnancies. Rates have increased in the
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is >37 weeks. In patients with preeclampsia with severe features or eclampsia, labor is induced once the gestational age is >34 weeks. In patients with gestational hypertension and no other signs of severe disease, labor is generally induced at term.
411:. The exact timing of when to induce labor is dependent on the severity of symptoms related to the hypertensive disease, as well as the medical condition of both the mother and the fetus. Generally, in mothers with preeclampsia, labor is induced once the 305:
There is no proven way to prevent preeclampsia/eclampsia. Most women who develop signs of preeclampsia, however, are closely monitored to lessen or avoid related problems. The only way to "cure" preeclampsia/eclampsia is to deliver or abort the baby.
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In cases where the fetus has not yet reached a safe gestational age to be delivered, management is focused on managing symptoms to give the fetus more time to mature. In women with gestational hypertension, some studies have found that usage of
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Clark SL, Christmas JT, Frye DR, Meyers JA, Perlin JB (July 2014). "Maternal mortality in the United States: predictability and the impact of protocols on fatal postcesarean pulmonary embolism and hypertension-related intracranial hemorrhage".
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High blood pressure problems occur in six percent to eight percent of all pregnancies in the U.S., about 70 percent of which are first-time pregnancies. In 1998, more than 146,320 cases of preeclampsia alone were diagnosed.
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uterus), and gestational diabetes. These women also face a higher risk for poor birth outcomes such as preterm delivery, having an infant small for his/her gestational age, and infant death.
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Steele, Dale W.; Adam, Gaelen P.; Saldanha, Ian J.; Kanaan, Ghid; Zahradnik, Michael L.; Danilack-Fekete, Valery A.; Stuebe, Alison M.; Peahl, Alex F.; Chen, Kenneth K.; Balk, Ethan M. (August 2023).
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Steele, Dale W.; Adam, Gaelen P.; Saldanha, Ian J.; Kanaan, Ghid; Zahradnik, Michael L.; Danilack-Fekete, Valery A.; Stuebe, Alison M.; Peahl, Alex F.; Chen, Kenneth K.; Balk, Ethan M. (2023-06-13).
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compared to women with normal blood pressure who had no complications in pregnancy. Monitoring pregnant women's blood pressure can help prevent both complications and future cardiovascular diseases.
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A classification of hypertensive disorders of pregnancy uses 4 categories as recommended by the U.S. National High Blood Pressure Education Program Working Group on High Blood Pressure in Pregnancy:
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is one particularly concerning form of preeclampsia in which a pregnant woman who previously presented with signs of newly increased blood pressure begins to experience new generalized
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American College of Obstetricians and Gynecologists' Committee on Practice Bulletins—Obstetrics (January 2019). "ACOG Practice Bulletin No. 203: Chronic Hypertension in Pregnancy".
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is a medical condition which usually develops after 20 weeks of gestation and traditionally involves both newly increased blood pressure (blood pressure > 140/90 mmHg) and
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Preeclampsia can also be diagnosed if a woman has both increased blood pressure and 1 or more signs of significant organ damage. Signs of significant organ damage include:
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This terminology is preferred over the older but widely used term pregnancy-induced hypertension (PIH) because it is more precise. The newer terminology reflects simply
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pressure monitoring lessens physical and financial barriers to blood pressure surveillance, likely decreasing health disparities between black and non-black patients.
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Berhan Y, Berhan A (June 2015). "Should magnesium sulfate be administered to women with mild pre-eclampsia? A systematic review of published reports on eclampsia".
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can prevent the progression of the condition to preeclampsia/eclampsia and reduce the risk of complications associated with hypertensive disorders of pregnancy.
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There is limited evidence to suggest that calcium supplementation may reduce the risk of pre-eclampsia or stillbirth but it is unclear if it has other benefits.
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Al Khalaf, Sukainah Y.; O'Reilly, Éilis J.; Barrett, Peter M.; B. Leite, Debora F.; Pawley, Lauren C.; McCarthy, Fergus P.; Khashan, Ali S. (4 May 2021).
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Low-Dose Aspirin for the Prevention of Morbidity and Mortality From Preeclampsia: A Systematic Evidence Review for the U.S. Preventive Services Task Force
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Gestational hypertension will normally resolve by 12 weeks postpartum. In this case, the diagnosis of gestational hypertension will be updated to be
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week of their first pregnancy, short-term complications, including increased blood pressure, usually go away within about six weeks after delivery.
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Women who developed high blood pressure or preeclampsia during a previous pregnancy, especially if these conditions occurred early in the pregnancy.
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Sibai BM (May 2004). "Diagnosis, controversies, and management of the syndrome of hemolysis, elevated liver enzymes, and low platelet count".
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with normal blood pressure. However, some women develop high blood pressure while they are pregnant (often called gestational hypertension).
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Sibai BM, Spinnato JA, Watson DL, Hill GA, Anderson GD (September 1984). "Pregnancy outcome in 303 cases with severe preeclampsia".
2886: 953: 1619:"Impact of Chronic Hypertension and Antihypertensive Treatment on Adverse Perinatal Outcomes: Systematic Review and Meta-Analysis" 2933: 2809: 2847: 334: 3198: 3165: 1326: 669: 325:. Up to 70% of patients with eclampsia experience complications associated with pregnancy. These complications can include 3686: 2781: 850:"Preeclampsia: Recent Advances in Predicting, Preventing, and Managing the Maternal and Fetal Life-Threatening Condition" 3213: 2921: 2891: 469:. Women who have high blood pressure and had complications in their pregnancy have three times the risk of developing 3616: 3471: 3398: 2786: 1377:"Calcium supplementation commencing before or early in pregnancy, for preventing hypertensive disorders of pregnancy" 742: 287:
If a woman with preeclampsia has any of these signs of significant organ damage, then her condition is classified as
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Al Khalaf, Sukainah; Chappell, Lucy C.; Khashan, Ali S.; McCarthy, Fergus P.; O’Reilly, Éilis J. (12 May 2023).
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Ankumah NE, Sibai BM (March 2017). "Chronic Hypertension in Pregnancy: Diagnosis, Management, and Outcomes".
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Women who have chronic hypertension before their pregnancy are at increased risk of complications such as
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Lo JO, Mission JF, Caughey AB (April 2013). "Hypertensive disease of pregnancy and maternal mortality".
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of pregnancy with either the onset or first detection of hypertension; the question of causation, while
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visit the doctor and, when pregnant, may initially present for prenatal care in the second trimester.
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in the gestational parent. Treatment should be continued from the time of diagnosis to several weeks
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Mammaro A, Carrara S, Cavaliere A, Ermito S, Dinatale A, Pappalardo EM, et al. (January 2009).
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interesting, is not the important point for most health care purposes. This classification treats
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Stone JH (August 1998). "HELLP syndrome: hemolysis, elevated liver enzymes, and low platelets".
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Podymow T, August P (2010). "Postpartum course of gestational hypertension and preeclampsia".
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weight gain during pregnancy can help reduce the risk of hypertension during pregnancy.
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Preeclampsia is a leading cause of fetal complications, which include low birth weight,
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Some women have a greater risk of developing hypertension during pregnancy. These are:
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Henderson JT, Whitlock EP, O'Conner E, Senger CA, Thompson JH, Rowland MG (2014).
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Women with diabetes, kidney disease, rheumatoid arthritis, lupus, or scleroderma.
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Sibai BM (February 2005). "Diagnosis, prevention, and management of eclampsia".
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WHO recommendations for prevention and treatment of pre-eclampsia and eclampsia
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Women with chronic hypertension (high blood pressure before becoming pregnant).
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The Convention on the Elimination of All Forms of Discrimination against Women
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in the pregnant mother. In this case, the patient would be diagnosed with
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approach to management of these conditions is to consider induction of
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is a type of preeclampsia with severe features that involves increased
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secondary to another condition; it is not caused by pregnancy itself.
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New or persistent headaches that do not respond to pain medication
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International Journal of Environmental Research and Public Health
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This article incorporates text from this source, which is in the
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This article incorporates text from this source, which is in the
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Severely elevated blood pressure (blood pressure > 160/110)
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Pruritic urticarial papules and plaques of pregnancy (PUPPP)
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as a type of preeclampsia rather than a parallel entity.
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Pregnant women under the age of 15 or over the age of 30.
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Declaration on the elimination of violence against women
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Hypertension: From basic research to clinical practice
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(October 2016). 210: 141:Women who are obese prior to pregnancy. 14: 3679: 1077: 1075: 1073: 1071: 1069: 1067: 1065: 1063: 1061: 1059: 1057: 751: 649: 335:disseminated intravascular coagulation 3199:Intrahepatic cholestasis of pregnancy 3166:Intrahepatic cholestasis of pregnancy 2949: 2547: 1733: 1422: 1420: 1274: 1272: 1240: 1205: 1170: 1166: 1164: 1055: 1053: 1051: 1049: 1047: 1045: 1043: 1041: 1039: 1037: 1001: 999: 997: 995: 993: 949: 947: 945: 910:"Hypertensive disorders of pregnancy" 601: 113: 3265:Pregnancy-induced hypercoagulability 2916: 2810:Office of Research on Women's Health 726: 2928: 2848:Society for Women's Health Research 2782:International Day of the Girl Child 1351:"Proper Nutrition During Pregnancy" 378:transient hypertension of pregnancy 373:develop some form of preeclampsia. 294:Preeclampsia can also present with 24: 3214:Pruritic folliculitis of pregnancy 2892:Birth control in the United States 1417: 1355:State of Israel Ministry of Health 1269: 1255:10.1097/01.AOG.0000126245.35811.2a 1185:10.1097/01.AOG.0000152351.13671.99 1161: 1034: 1008:Clinical Obstetrics and Gynecology 990: 942: 25: 3708: 3472:Pain management during childbirth 3399:Twin-to-twin transfusion syndrome 2787:Commission on the Status of Women 1797:External female genitalia (vulva) 1711:10.1161/HYPERTENSIONAHA.122.20628 340: 289:preeclampsia with severe features 167: 76:Hypertensive disease of pregnancy 33:Hypertensive disease of pregnancy 3658: 3657: 3644:Sexual activity during pregnancy 2927: 2915: 2904: 2903: 2120:Assisted reproductive technology 1760: 829: 795: 18:Hypertensive states of pregnancy 2086:Breastfeeding and mental health 1685: 1659: 1610: 1569: 1524: 1481: 1445: 1368: 1343: 1234: 1199: 1118: 696:(9963): 117–171. January 2015. 480: 126: 3146:Acute fatty liver of pregnancy 1393:10.1002/14651858.CD011192.pub3 841: 807: 678: 80:maternal hypertensive disorder 41:Maternal hypertensive disorder 13: 1: 3348:Prelabor rupture of membranes 2736:Social determinants of health 702:10.1016/S0140-6736(14)61682-2 577:10.1016/s0140-6736(16)31012-1 528:10.1016/S0140-6736(16)31678-6 493: 401: 389: 3627:Systemic lupus erythematosus 3278:Maternal care related to the 3260:Gestational thrombocytopenia 2731:Gender disparities in health 2069:Mother-to-child transmission 1595:10.1097/AOG.0000000000005270 1546:10.1097/AOG.0000000000005270 1096:10.1097/AOG.0000000000003892 1020:10.1097/GRF.0000000000000255 968:10.1097/AOG.0000000000003020 914:Journal of Prenatal Medicine 627:10.1097/gco.0b013e32835e0ef5 448: 309: 154: 7: 3428:Cephalopelvic disproportion 2344:Pelvic inflammatory disease 2287:Hormone replacement therapy 1851:Reproductive system disease 1582:Obstetrics & Gynecology 1537:Obstetrics & Gynecology 1090:(6): 1492–1495. June 2020. 228:Pre-eclampsia and eclampsia 10: 3713: 3687:Health issues in pregnancy 3539:Breastfeeding difficulties 3338:Constriction ring syndrome 3312:Braxton Hicks contractions 2838:Black Women's Health Study 1905:Complications of pregnancy 1679:10.3310/nihrevidence_60660 1467:10.1016/j.ajog.2014.03.031 3652: 3609: 3576:Peripartum cardiomyopathy 3566:Pubic symphysis diastasis 3529: 3413: 3277: 3250: 3232: 3174: 3136: 3127: 3083: 3001: 2992: 2899: 2856: 2815:Women's Health Initiative 2800: 2762: 2753: 2702: 2668:Major depressive disorder 2536: 2496:Intimate partner violence 2458: 2357:Female genital mutilation 2352: 2301: 2210: 2152: 2098: 2044: 1957: 1870: 1859: 1785: 1772: 1502:10.3109/10641950902777747 1490:Hypertension in Pregnancy 1281:Obstetrics and Gynecology 1243:Obstetrics and Gynecology 1173:Obstetrics and Gynecology 1084:Obstetrics and Gynecology 956:Obstetrics and Gynecology 283:Blurred or altered vision 65: 57: 45: 37: 32: 3102:Gestational hypertension 2404:Gynaecological disorders 2220:Culture and menstruation 2187:Contraceptive prevalence 2079:Compulsory sterilization 370:Gestational hypertension 365:Gestational hypertension 189:Gestational hypertension 88:gestational hypertension 3501:Umbilical cord prolapse 3423:Amniotic fluid embolism 3181:dermatoses of pregnancy 2687:Urinary tract infection 2479:Abuse during childbirth 1635:10.1161/JAHA.120.018494 272:Increased liver enzymes 3617:Concomitant conditions 3596:Postpartum thyroiditis 3374:Circumvallate placenta 3194:Impetigo herpetiformis 3189:Gestational pemphigoid 3161:Hyperemesis gravidarum 3094:hypertensive disorders 2604:Cardiovascular disease 2192:Contraceptive security 2125:In vitro fertilization 2036:Postpartum confinement 1910:Hyperemesis gravidarum 1220:10.1001/jama.280.6.559 867:10.3390/ijerph20042994 471:cardiovascular disease 3586:Postpartum infections 3581:Postpartum depression 2726:Healthcare inequality 2528:Gender discrimination 2332:Human papilloma virus 2007:Vesicovaginal fistula 176:Chronic hypertension; 3591:Postpartum psychosis 3460:Obstetrical bleeding 3355:Obstetrical bleeding 3176:Integumentary system 3151:Gestational diabetes 3130:related to pregnancy 3128:Other, predominantly 2833:Nurses' Health Study 2741:Reproductive justice 2692:Urinary incontinence 2312:Sexually transmitted 2167:Intrauterine devices 2012:Rectovaginal fistula 2002:Obstetrical fistulae 1930:Gestational diabetes 1925:Obstetrical bleeding 1900:Adolescent pregnancy 1885:Gravidity and parity 1880:Unintended pregnancy 1319:10.1007/5584_2016_82 571:(10053): 1459–1544. 522:(10053): 1545–1602. 383:chronic hypertension 211:Chronic hypertension 108:puerperal infections 104:post partum bleeding 92:chronic hypertension 3571:Postpartum bleeding 3394:Placental abruption 3379:Monochorionic twins 3209:Prurigo gestationis 2746:Women's empowerment 2614:Alzheimer's disease 2245:Cloth menstrual pad 2202:Fertility awareness 2172:Oral contraceptives 2054:Perinatal mortality 1249:(5 Pt 1): 981–991. 735:Williams obstetrics 331:acute kidney injury 61:20.7 million (2015) 3601:Puerperal mastitis 3556:Breast engorgement 3343:Monoamniotic twins 3333:Chorionic hematoma 2843:Cartwright Inquiry 2754:Politics, research 2572:Endometrial cancer 2426:Sexual intercourse 2197:Planned parenthood 2182:Male contraceptive 1461:(1): 32.e1–32.e9. 114:Signs and symptoms 3674: 3673: 3632:Thyroid disorders 3622:Diabetes mellitus 3506:Uterine inversion 3438:Shoulder dystocia 3433:Obstructed labour 3409: 3408: 3273: 3272: 3242:Chorea gravidarum 3018:Ectopic pregnancy 2943: 2942: 2823: 2822: 2648: 2647: 2599: 2598: 2582:Papanicolaou test 2538:Non-communicable 2506:Sexual harassment 2484:Domestic violence 2454: 2453: 2297: 2296: 2094: 2093: 1997:Retained placenta 1915:Ectopic pregnancy 1328:978-3-319-44250-1 1139:10.1111/jog.12697 780:www.nhlbi.nih.gov 671:978-92-4-154833-5 434:magnesium sulfate 73: 72: 27:Medical condition 16:(Redirected from 3704: 3661: 3660: 3496:Postmature birth 3484:Placenta accreta 3389:Placenta praevia 3384:Placenta accreta 3328:Chorioamnionitis 3138:Digestive system 3134: 3133: 3060:Fetal resorption 3048:Rudimentary horn 3005:abortive outcome 2999: 2998: 2970: 2963: 2956: 2947: 2946: 2931: 2930: 2919: 2918: 2907: 2906: 2760: 2759: 2545: 2544: 2465: 2464: 2459:Non-reproductive 2308: 2307: 2225:Feminine hygiene 1992:Cesarian section 1987:Obstructed labor 1868: 1867: 1783: 1782: 1764: 1754: 1747: 1740: 1731: 1730: 1724: 1723: 1713: 1704:(7): 1427–1438. 1689: 1683: 1682: 1663: 1657: 1656: 1646: 1614: 1608: 1607: 1597: 1573: 1567: 1566: 1548: 1528: 1522: 1521: 1485: 1479: 1478: 1449: 1443: 1442: 1424: 1415: 1414: 1404: 1372: 1366: 1365: 1363: 1361: 1347: 1341: 1340: 1306: 1297: 1296: 1276: 1267: 1266: 1238: 1232: 1231: 1203: 1197: 1196: 1168: 1159: 1158: 1122: 1116: 1115: 1079: 1032: 1031: 1003: 988: 987: 951: 940: 939: 929: 905: 890: 889: 879: 869: 845: 839: 833: 832: 828: 826: 825: 811: 805: 799: 798: 794: 792: 791: 782:. Archived from 772: 749: 748: 730: 724: 723: 713: 682: 676: 675: 663: 653: 647: 646: 610: 599: 598: 588: 556: 550: 549: 539: 507: 261:Thrombocytopenia 201:pathogenetically 100:developing world 78:, also known as 30: 29: 21: 3712: 3711: 3707: 3706: 3705: 3703: 3702: 3701: 3677: 3676: 3675: 3670: 3648: 3605: 3549:Cracked nipples 3544:Low milk supply 3525: 3511:Uterine rupture 3405: 3300:Oligohydramnios 3285:amniotic cavity 3279: 3269: 3246: 3228: 3179: 3170: 3129: 3123: 3092: 3079: 3065:Molar pregnancy 3004: 2988: 2974: 2944: 2939: 2895: 2880:Family planning 2858: 2852: 2819: 2796: 2755: 2749: 2721:Gender equality 2704: 2698: 2644: 2595: 2577:Cervical cancer 2539: 2532: 2470: 2460: 2450: 2441:Sex differences 2399:Forced marriage 2348: 2313: 2303: 2293: 2235:Menstrual cycle 2206: 2159:Family planning 2157: 2148: 2101: 2090: 2049:Maternal deaths 2040: 2031:Postpartum care 1977:Multiple births 1953: 1862: 1855: 1788: 1779: 1776: 1768: 1758: 1728: 1727: 1690: 1686: 1665: 1664: 1660: 1615: 1611: 1574: 1570: 1529: 1525: 1486: 1482: 1450: 1446: 1425: 1418: 1387:(9): CD011192. 1373: 1369: 1359: 1357: 1349: 1348: 1344: 1329: 1307: 1300: 1277: 1270: 1239: 1235: 1204: 1200: 1169: 1162: 1123: 1119: 1081: 1080: 1035: 1004: 991: 952: 943: 906: 893: 846: 842: 830: 823: 821: 813: 812: 808: 796: 789: 787: 774: 773: 752: 745: 732: 731: 727: 684: 683: 679: 672: 661: 655: 654: 650: 611: 602: 557: 553: 508: 501: 496: 483: 463:low birthweight 459:premature birth 451: 413:gestational age 404: 392: 367: 358: 343: 312: 276:Pulmonary edema 230: 213: 170: 157: 129: 116: 28: 23: 22: 15: 12: 11: 5: 3710: 3700: 3699: 3694: 3692:Women's health 3689: 3672: 3671: 3669: 3668: 3653: 3650: 3649: 3647: 3646: 3641: 3639:Maternal death 3636: 3635: 3634: 3629: 3624: 3613: 3611: 3607: 3606: 3604: 3603: 3598: 3593: 3588: 3583: 3578: 3573: 3568: 3563: 3558: 3553: 3552: 3551: 3546: 3535: 3533: 3527: 3526: 3524: 3523: 3518: 3513: 3508: 3503: 3498: 3493: 3488: 3487: 3486: 3474: 3469: 3468: 3467: 3457: 3452: 3447: 3445:Fetal distress 3442: 3441: 3440: 3430: 3425: 3419: 3417: 3411: 3410: 3407: 3406: 3404: 3403: 3402: 3401: 3396: 3391: 3386: 3381: 3376: 3364: 3363: 3362: 3352: 3351: 3350: 3345: 3340: 3335: 3330: 3314: 3309: 3308: 3307: 3305:Polyhydramnios 3302: 3294:amniotic fluid 3289: 3287: 3275: 3274: 3271: 3270: 3268: 3267: 3262: 3256: 3254: 3248: 3247: 3245: 3244: 3238: 3236: 3234:Nervous system 3230: 3229: 3227: 3226: 3221: 3216: 3211: 3206: 3201: 3196: 3191: 3185: 3183: 3172: 3171: 3169: 3168: 3163: 3158: 3153: 3148: 3142: 3140: 3131: 3125: 3124: 3122: 3121: 3116: 3115: 3114: 3112:HELLP syndrome 3104: 3098: 3096: 3081: 3080: 3078: 3077: 3072: 3067: 3062: 3057: 3052: 3051: 3050: 3045: 3040: 3035: 3030: 3025: 3015: 3009: 3007: 3003:Pregnancy with 2996: 2990: 2989: 2973: 2972: 2965: 2958: 2950: 2941: 2940: 2938: 2937: 2925: 2913: 2900: 2897: 2896: 2894: 2889: 2884: 2883: 2882: 2872: 2867: 2862: 2860: 2857:Women's health 2854: 2853: 2851: 2850: 2845: 2840: 2835: 2830: 2824: 2821: 2820: 2818: 2817: 2812: 2806: 2804: 2798: 2797: 2795: 2794: 2789: 2784: 2779: 2774: 2768: 2766: 2764:United Nations 2757: 2756:& advocacy 2751: 2750: 2748: 2743: 2738: 2733: 2728: 2723: 2718: 2713: 2708: 2706: 2703:Sociocultural 2700: 2699: 2697: 2696: 2695: 2694: 2689: 2684: 2674: 2673: 2672: 2671: 2670: 2660: 2649: 2646: 2645: 2643: 2642: 2637: 2636: 2635: 2634: 2633: 2618: 2617: 2616: 2606: 2600: 2597: 2596: 2594: 2593: 2591:Ovarian cancer 2588: 2587: 2586: 2585: 2584: 2574: 2567:Uterine cancer 2564: 2559: 2553: 2551: 2542: 2534: 2533: 2531: 2530: 2525: 2520: 2519: 2518: 2511:Sexual assault 2508: 2503: 2498: 2493: 2492: 2491: 2481: 2475: 2473: 2462: 2456: 2455: 2452: 2451: 2449: 2448: 2443: 2438: 2433: 2428: 2423: 2418: 2413: 2412: 2411: 2401: 2396: 2391: 2389:Child marriage 2386: 2384:Breast ironing 2381: 2376: 2374:Breast binding 2371: 2370: 2369: 2364: 2362:Clitoridectomy 2353: 2350: 2349: 2347: 2346: 2341: 2340: 2339: 2329: 2324: 2318: 2316: 2305: 2299: 2298: 2295: 2294: 2292: 2291: 2290: 2289: 2279: 2274: 2269: 2264: 2263: 2262: 2257: 2252: 2247: 2240:Menstrual aids 2237: 2232: 2227: 2222: 2216: 2214: 2208: 2207: 2205: 2204: 2199: 2194: 2189: 2184: 2179: 2174: 2169: 2163: 2161: 2150: 2149: 2147: 2146: 2145: 2144: 2139: 2129: 2128: 2127: 2122: 2117: 2106: 2104: 2096: 2095: 2092: 2091: 2089: 2088: 2083: 2082: 2081: 2071: 2066: 2061: 2056: 2051: 2045: 2042: 2041: 2039: 2038: 2033: 2028: 2027: 2026: 2024:Husband stitch 2016: 2015: 2014: 2009: 1999: 1994: 1989: 1984: 1979: 1974: 1969: 1963: 1961: 1955: 1954: 1952: 1951: 1950: 1949: 1948: 1947: 1942: 1932: 1927: 1922: 1917: 1912: 1902: 1897: 1895:Antenatal care 1892: 1887: 1882: 1876: 1874: 1865: 1857: 1856: 1854: 1853: 1848: 1843: 1841:Fallopian tube 1838: 1833: 1828: 1823: 1822: 1821: 1816: 1811: 1810: 1809: 1793: 1791: 1787:Reproductive 1780: 1773: 1770: 1769: 1766:Women's health 1757: 1756: 1749: 1742: 1734: 1726: 1725: 1684: 1658: 1629:(9): e018494. 1609: 1588:(2): 285–295. 1568: 1523: 1496:(3): 294–300. 1480: 1444: 1416: 1367: 1342: 1327: 1298: 1287:(3): 319–325. 1268: 1233: 1214:(6): 559–562. 1198: 1179:(2): 402–410. 1160: 1133:(6): 831–842. 1117: 1033: 1014:(1): 206–214. 989: 962:(1): e26–e50. 941: 891: 840: 806: 750: 743: 725: 677: 670: 648: 621:(2): 124–132. 600: 551: 498: 497: 495: 492: 482: 479: 450: 447: 403: 400: 391: 388: 366: 363: 357: 354: 346:HELLP Syndrome 342: 341:HELLP Syndrome 339: 337:among others. 327:HELLP syndrome 311: 308: 285: 284: 281: 278: 273: 270: 263: 258: 229: 226: 212: 209: 205:HELLP syndrome 193: 192: 186: 183: 177: 169: 168:Classification 166: 156: 153: 152: 151: 148: 145: 142: 139: 136: 128: 125: 115: 112: 71: 70: 67: 63: 62: 59: 55: 54: 49: 43: 42: 39: 35: 34: 26: 9: 6: 4: 3: 2: 3709: 3698: 3695: 3693: 3690: 3688: 3685: 3684: 3682: 3667: 3666: 3662: 3655: 3654: 3651: 3645: 3642: 3640: 3637: 3633: 3630: 3628: 3625: 3623: 3620: 3619: 3618: 3615: 3614: 3612: 3608: 3602: 3599: 3597: 3594: 3592: 3589: 3587: 3584: 3582: 3579: 3577: 3574: 3572: 3569: 3567: 3564: 3562: 3559: 3557: 3554: 3550: 3547: 3545: 3542: 3541: 3540: 3537: 3536: 3534: 3532: 3528: 3522: 3521:Uterine atony 3519: 3517: 3514: 3512: 3509: 3507: 3504: 3502: 3499: 3497: 3494: 3492: 3491:Preterm birth 3489: 3485: 3482: 3481: 3480: 3479: 3475: 3473: 3470: 3466: 3463: 3462: 3461: 3458: 3456: 3453: 3451: 3448: 3446: 3443: 3439: 3436: 3435: 3434: 3431: 3429: 3426: 3424: 3421: 3420: 3418: 3416: 3412: 3400: 3397: 3395: 3392: 3390: 3387: 3385: 3382: 3380: 3377: 3375: 3372: 3371: 3370: 3369: 3365: 3361: 3358: 3357: 3356: 3353: 3349: 3346: 3344: 3341: 3339: 3336: 3334: 3331: 3329: 3326: 3325: 3324: 3323: 3319: 3315: 3313: 3310: 3306: 3303: 3301: 3298: 3297: 3296: 3295: 3291: 3290: 3288: 3286: 3282: 3276: 3266: 3263: 3261: 3258: 3257: 3255: 3253: 3249: 3243: 3240: 3239: 3237: 3235: 3231: 3225: 3224:Stretch marks 3222: 3220: 3217: 3215: 3212: 3210: 3207: 3205: 3202: 3200: 3197: 3195: 3192: 3190: 3187: 3186: 3184: 3182: 3177: 3173: 3167: 3164: 3162: 3159: 3157: 3154: 3152: 3149: 3147: 3144: 3143: 3141: 3139: 3135: 3132: 3126: 3120: 3117: 3113: 3110: 3109: 3108: 3107:Pre-eclampsia 3105: 3103: 3100: 3099: 3097: 3095: 3090: 3086: 3082: 3076: 3073: 3071: 3068: 3066: 3063: 3061: 3058: 3056: 3053: 3049: 3046: 3044: 3041: 3039: 3036: 3034: 3031: 3029: 3026: 3024: 3021: 3020: 3019: 3016: 3014: 3011: 3010: 3008: 3006: 3000: 2997: 2995: 2991: 2987: 2983: 2979: 2976:Pathology of 2971: 2966: 2964: 2959: 2957: 2952: 2951: 2948: 2936: 2935: 2926: 2924: 2923: 2914: 2912: 2911: 2902: 2901: 2898: 2893: 2890: 2888: 2885: 2881: 2878: 2877: 2876: 2873: 2871: 2868: 2866: 2863: 2861: 2855: 2849: 2846: 2844: 2841: 2839: 2836: 2834: 2831: 2829: 2826: 2825: 2816: 2813: 2811: 2808: 2807: 2805: 2803: 2802:United States 2799: 2793: 2790: 2788: 2785: 2783: 2780: 2778: 2775: 2773: 2770: 2769: 2767: 2765: 2761: 2758: 2752: 2747: 2744: 2742: 2739: 2737: 2734: 2732: 2729: 2727: 2724: 2722: 2719: 2717: 2716:Disadvantaged 2714: 2712: 2709: 2707: 2701: 2693: 2690: 2688: 2685: 2683: 2680: 2679: 2678: 2677:Urinary tract 2675: 2669: 2666: 2665: 2664: 2661: 2659: 2656: 2655: 2654: 2653:Mental health 2651: 2650: 2641: 2638: 2632: 2629: 2628: 2627: 2624: 2623: 2622: 2619: 2615: 2612: 2611: 2610: 2607: 2605: 2602: 2601: 2592: 2589: 2583: 2580: 2579: 2578: 2575: 2573: 2570: 2569: 2568: 2565: 2563: 2562:Breast cancer 2560: 2558: 2555: 2554: 2552: 2550: 2546: 2543: 2541: 2535: 2529: 2526: 2524: 2521: 2517: 2514: 2513: 2512: 2509: 2507: 2504: 2502: 2499: 2497: 2494: 2490: 2487: 2486: 2485: 2482: 2480: 2477: 2476: 2474: 2472: 2471:against women 2466: 2463: 2457: 2447: 2446:Sex education 2444: 2442: 2439: 2437: 2434: 2432: 2429: 2427: 2424: 2422: 2419: 2417: 2414: 2410: 2407: 2406: 2405: 2402: 2400: 2397: 2395: 2392: 2390: 2387: 2385: 2382: 2380: 2379:Breast health 2377: 2375: 2372: 2368: 2365: 2363: 2360: 2359: 2358: 2355: 2354: 2351: 2345: 2342: 2338: 2335: 2334: 2333: 2330: 2328: 2325: 2323: 2320: 2319: 2317: 2315: 2309: 2306: 2300: 2288: 2285: 2284: 2283: 2280: 2278: 2275: 2273: 2270: 2268: 2265: 2261: 2258: 2256: 2253: 2251: 2250:Menstrual cup 2248: 2246: 2243: 2242: 2241: 2238: 2236: 2233: 2231: 2228: 2226: 2223: 2221: 2218: 2217: 2215: 2213: 2209: 2203: 2200: 2198: 2195: 2193: 2190: 2188: 2185: 2183: 2180: 2178: 2175: 2173: 2170: 2168: 2165: 2164: 2162: 2160: 2155: 2154:Contraception 2151: 2143: 2140: 2138: 2135: 2134: 2133: 2130: 2126: 2123: 2121: 2118: 2116: 2115:Childlessness 2113: 2112: 2111: 2108: 2107: 2105: 2103: 2100:Reproductive 2097: 2087: 2084: 2080: 2077: 2076: 2075: 2074:Sterilization 2072: 2070: 2067: 2065: 2062: 2060: 2057: 2055: 2052: 2050: 2047: 2046: 2043: 2037: 2034: 2032: 2029: 2025: 2022: 2021: 2020: 2017: 2013: 2010: 2008: 2005: 2004: 2003: 2000: 1998: 1995: 1993: 1990: 1988: 1985: 1983: 1980: 1978: 1975: 1973: 1972:Preterm birth 1970: 1968: 1965: 1964: 1962: 1960: 1956: 1946: 1943: 1941: 1938: 1937: 1936: 1933: 1931: 1928: 1926: 1923: 1921: 1918: 1916: 1913: 1911: 1908: 1907: 1906: 1903: 1901: 1898: 1896: 1893: 1891: 1888: 1886: 1883: 1881: 1878: 1877: 1875: 1873: 1869: 1866: 1864: 1858: 1852: 1849: 1847: 1844: 1842: 1839: 1837: 1834: 1832: 1829: 1827: 1824: 1820: 1817: 1815: 1812: 1808: 1807:Clitoral hood 1805: 1804: 1803: 1800: 1799: 1798: 1795: 1794: 1792: 1790: 1784: 1781: 1778: 1775:Reproductive 1771: 1767: 1763: 1755: 1750: 1748: 1743: 1741: 1736: 1735: 1732: 1721: 1717: 1712: 1707: 1703: 1699: 1695: 1688: 1680: 1676: 1672: 1671:NIHR Evidence 1668: 1662: 1654: 1650: 1645: 1640: 1636: 1632: 1628: 1624: 1620: 1613: 1605: 1601: 1596: 1591: 1587: 1583: 1579: 1572: 1564: 1560: 1556: 1552: 1547: 1542: 1538: 1534: 1527: 1519: 1515: 1511: 1507: 1503: 1499: 1495: 1491: 1484: 1476: 1472: 1468: 1464: 1460: 1456: 1448: 1440: 1436: 1432: 1431: 1423: 1421: 1412: 1408: 1403: 1398: 1394: 1390: 1386: 1382: 1378: 1371: 1356: 1352: 1346: 1338: 1334: 1330: 1324: 1320: 1316: 1312: 1305: 1303: 1294: 1290: 1286: 1282: 1275: 1273: 1264: 1260: 1256: 1252: 1248: 1244: 1237: 1229: 1225: 1221: 1217: 1213: 1209: 1202: 1194: 1190: 1186: 1182: 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Index

Hypertensive states of pregnancy
Specialty
Obstetrics
preeclampsia
gestational hypertension
chronic hypertension
developing world
post partum bleeding
puerperal infections
Preeclampsia
Gestational hypertension
relation
pathogenetically
HELLP syndrome
Preeclampsia
proteinuria
preterm birth
stillbirth
Thrombocytopenia
creatinine
Pulmonary edema
seizures
eclampsia
Eclampsia
seizures
coma
HELLP syndrome
acute kidney injury
disseminated intravascular coagulation
HELLP Syndrome

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