Knowledge

HLA-A23

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Arce-Gomez B, Jones EA, Barnstable CJ, Solomon E, Bodmer WF (February 1978). "The genetic control of HLA-A and B antigens in somatic cell hybrids: requirement for beta2 microglobulin".
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serotype group. The serotype is determined by the antibody recognition of α subset of HLA-A α-chains. For A23, the alpha, "A", chain are encoded by the HLA-A
912:"Favorable and unfavorable HLA class I alleles and haplotypes in Zambians predominantly infected with clade C human immunodeficiency virus type 1" 20: 977: 873:
Middleton, D.; Menchaca, L.; Rood, H.; Komerofsky, R. (2003). "New allele frequency database: http://www.allelefrequencies.net".
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A23 is common in Africa and regions of the Middle East, Mediterranean, and India than Europe, East Asia or the Americas.
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Tang J, Tang S, Lobashevsky E, Myracle A, Fideli U, Aldrovandi G, Allen S, Musonda R, Kaslow R (2002).
875: 963: 181: 1154: 150: 68: 857: 165: 198: 101: 79: 8: 833: 936: 911: 213: 209: 941: 927: 892: 888: 837: 931: 923: 884: 829: 773: 92: 1148: 854: 945: 896: 85: 34: 841: 233: 201: 304: 47: 989: 185: 955: 1133: 1128: 1121: 1116: 1111: 1104: 1099: 1094: 1089: 1084: 1079: 1074: 1069: 1062: 1057: 1052: 1047: 1042: 1037: 1030: 790:
A23-B44 is found in Albania, Zimbabwe, Morocco, Spain and Danes.
220: 63: 819: 1020: 1015: 1010: 1005: 872: 216: 72: 1000: 986: 190: 97: 38: 909: 801: 204:. This group currently is dominated by A*2301. A23 and A 800:A*23:Cw*07 is associated with higher viral load in 788:
A23-B7 is found in N.Afr. and S.Afr non-caucasians.
1146: 235:A23 recognition of some HLA A*23 gene products 21:History and naming of human leukocyte antigens 971: 197:allele group and the β-chain are encoded by 866: 208:are almost synonymous in meaning. A23 is a 978: 964: 46: 935: 792:A23-B58 is found in the !kung and Zaire. 903: 813: 1147: 795: 959: 985: 13: 834:10.1111/j.1399-0039.1978.tb01233.x 14: 1166: 862:European Bioinformatics Institute 928:10.1128/JVI.76.16.8276-8284.2002 889:10.1034/j.1399-0039.2003.00062.x 16:Human leukocyte antigen serotype 219:and it is a sister serotype of 848: 1: 806: 783: 7: 229: 10: 1171: 640:USA North American Native… 592:Spain Basque Gipuzkoa Pro… 512:Saudi Arabia Guraiat and … 432:Morocco Berber Nador Meta… 360:Cape Verde Southeastern I… 18: 996: 771: 767: 759: 751: 743: 735: 727: 719: 711: 703: 695: 687: 679: 671: 663: 655: 647: 639: 631: 623: 616:Georgia Tbilisi Georgian… 615: 607: 600:Australia New South Wales 599: 591: 583: 575: 567: 559: 551: 544:USA South Texas Hispanics 543: 535: 527: 519: 511: 503: 495: 487: 479: 471: 463: 455: 447: 439: 431: 423: 415: 407: 399: 391: 383: 375: 367: 359: 351: 343: 336:Senegal Niokholo Mandenka 335: 327: 319: 315: 300: 290: 163: 145: 140:Available structures 128: 124: 119: 111: 91: 78: 62: 57: 45: 32: 27: 400:South African Natal Zulu 182:human leukocyte antigen 520:Spain Catalonia Girona 296:HLA A*2301 frequencies 69:transmembrane receptor 472:Georgia Tbilisi Kurds 376:Zimbabwe Harare Shona 41:cell surface antigen) 648:China Inner Mongolia 164:Alleles link-out to 796:Associated diseases 384:USA African America 297: 236: 774:Allele frequencies 752:India North Hindus 295: 234: 1142: 1141: 855:Allele Query Form 781: 780: 777: 720:Italy North Pavia 712:France South East 704:USA Caucasian (2) 560:Russia Tuva pop 2 536:Venezuela Caracus 504:Israel Arab Druse 352:Cameroon Bamileke 311: 288: 287: 175: 174: 159: 158: 1162: 980: 973: 966: 957: 956: 950: 949: 939: 907: 901: 900: 870: 864: 852: 846: 845: 817: 772: 672:Ireland Northern 328:Cameroon Yaounde 309: 301:Study population 298: 294: 281: 251: 237: 207: 196: 153: 126: 125: 50: 25: 24: 1170: 1169: 1165: 1164: 1163: 1161: 1160: 1159: 1145: 1144: 1143: 1138: 992: 984: 954: 953: 922:(16): 8276–84. 908: 904: 876:Tissue Antigens 871: 867: 853: 849: 822:Tissue Antigens 818: 814: 809: 798: 791: 789: 786: 776:presented, only 760:Portugal Centre 696:Pakistan Sindhi 688:Mongolia Buriat 664:Pakistan Pathan 656:India New Delhi 552:Mexico Mestizos 320:Mali Bandiagara 307: 293: 279: 249: 232: 205: 194: 149: 141: 136: 131: 105: 53: 23: 17: 12: 11: 5: 1168: 1158: 1157: 1140: 1139: 1137: 1136: 1131: 1126: 1125: 1124: 1119: 1109: 1108: 1107: 1102: 1097: 1092: 1087: 1082: 1072: 1067: 1066: 1065: 1060: 1055: 1050: 1045: 1035: 1034: 1033: 1028: 1018: 1013: 1008: 1003: 997: 994: 993: 983: 982: 975: 968: 960: 952: 951: 902: 883:(5): 403–407. 865: 847: 811: 810: 808: 805: 797: 794: 785: 782: 779: 778: 769: 768: 765: 764: 761: 757: 756: 753: 749: 748: 745: 744:France Corsica 741: 740: 737: 733: 732: 729: 725: 724: 721: 717: 716: 713: 709: 708: 705: 701: 700: 697: 693: 692: 689: 685: 684: 681: 677: 676: 673: 669: 668: 665: 661: 660: 657: 653: 652: 649: 645: 644: 641: 637: 636: 633: 629: 628: 625: 621: 620: 617: 613: 612: 609: 608:Czech Republic 605: 604: 601: 597: 596: 593: 589: 588: 585: 581: 580: 577: 573: 572: 569: 565: 564: 561: 557: 556: 553: 549: 548: 545: 541: 540: 537: 533: 532: 529: 525: 524: 521: 517: 516: 513: 509: 508: 505: 501: 500: 497: 493: 492: 489: 485: 484: 481: 480:Portugal South 477: 476: 473: 469: 468: 465: 464:Uganda Kampala 461: 460: 457: 453: 452: 449: 445: 444: 441: 437: 436: 433: 429: 428: 425: 421: 420: 417: 413: 412: 409: 405: 404: 401: 397: 396: 393: 392:Portugal North 389: 388: 385: 381: 380: 377: 373: 372: 369: 365: 364: 361: 357: 356: 353: 349: 348: 345: 341: 340: 337: 333: 332: 329: 325: 324: 321: 317: 316: 313: 312: 302: 292: 289: 286: 285: 282: 277: 274: 270: 269: 266: 263: 260: 256: 255: 252: 246: 241: 231: 228: 173: 172: 161: 160: 157: 156: 154: 147: 143: 142: 139: 137: 134: 132: 129: 122: 121: 117: 116: 113: 109: 108: 106:-microglobulin 103: 95: 89: 88: 82: 76: 75: 66: 60: 59: 55: 54: 51: 43: 42: 30: 29: 15: 9: 6: 4: 3: 2: 1167: 1156: 1155:HLA-A alleles 1153: 1152: 1150: 1135: 1132: 1130: 1127: 1123: 1120: 1118: 1115: 1114: 1113: 1110: 1106: 1103: 1101: 1098: 1096: 1093: 1091: 1088: 1086: 1083: 1081: 1078: 1077: 1076: 1073: 1071: 1068: 1064: 1061: 1059: 1056: 1054: 1051: 1049: 1046: 1044: 1041: 1040: 1039: 1036: 1032: 1029: 1027: 1024: 1023: 1022: 1019: 1017: 1014: 1012: 1009: 1007: 1004: 1002: 999: 998: 995: 991: 988: 981: 976: 974: 969: 967: 962: 961: 958: 947: 943: 938: 933: 929: 925: 921: 917: 913: 906: 898: 894: 890: 886: 882: 878: 877: 869: 863: 859: 856: 851: 843: 839: 835: 831: 828:(2): 96–112. 827: 823: 816: 812: 804: 803: 793: 775: 770: 766: 762: 758: 754: 750: 746: 742: 738: 736:Italy Bergamo 734: 730: 726: 722: 718: 714: 710: 706: 702: 698: 694: 690: 686: 682: 678: 674: 670: 666: 662: 658: 654: 650: 646: 642: 638: 634: 630: 626: 622: 618: 614: 610: 606: 602: 598: 594: 590: 586: 582: 578: 574: 570: 566: 562: 558: 554: 550: 546: 542: 538: 534: 530: 526: 522: 518: 514: 510: 506: 502: 498: 494: 490: 486: 482: 478: 474: 470: 466: 462: 458: 454: 450: 448:China Beijing 446: 442: 440:Zambia Lusaka 438: 434: 430: 426: 422: 418: 414: 410: 408:Cuban Mulatto 406: 402: 398: 394: 390: 386: 382: 378: 374: 370: 368:Cameroon Beti 366: 362: 358: 354: 350: 346: 344:Guinea Bissau 342: 338: 334: 330: 326: 322: 318: 314: 306: 303: 299: 283: 278: 275: 272: 271: 267: 264: 261: 258: 257: 253: 247: 245: 242: 239: 238: 227: 224: 222: 218: 215: 214:broad antigen 211: 210:split antigen 203: 200: 192: 188: 187: 183: 179: 171: 167: 162: 155: 152: 148: 144: 138: 133: 127: 123: 118: 114: 110: 107: 99: 96: 94: 90: 87: 83: 81: 77: 74: 70: 67: 65: 61: 56: 49: 44: 40: 36: 31: 26: 22: 1025: 919: 915: 905: 880: 874: 868: 850: 825: 821: 815: 799: 787: 680:Jordan Amman 243: 225: 184: 177: 176: 168:database at 728:Iran Baloch 456:Kenya Nandi 310:(in %) 180:(A23) is a 112:Older names 86:heterodimer 35:MHC Class I 807:References 784:Haplotypes 19:See also: 990:serotypes 424:Kenya Luo 268:size (N) 80:Structure 1149:Category 946:12134033 897:12753660 858:IMGT/HLA 568:Romanian 496:Bulgaria 488:Sudanese 230:Serotype 186:serotype 166:IMGT/HLA 120:Subtypes 93:Subunits 916:J Virol 632:Belgium 576:Croatia 416:Tunisia 254:Sample 221:HLA-A24 212:of the 189:within 178:HLA-A23 130:Subtype 100:*2301, 64:Protein 52:HLA-A23 28:HLA-A23 944:  937:155130 934:  895:  840:  584:Brazil 308:  291:Allele 259:allele 217:HLA-A9 135:allele 73:ligand 1001:HLA-A 987:HLA-A 842:77067 528:Kenya 305:Freq. 284:5119 273:*2301 240:A*23 202:locus 191:HLA-A 151:*2301 115:HL-A9 98:HLA-A 58:About 942:PMID 893:PMID 838:PMID 624:Oman 403:10.0 395:10.9 387:11.1 379:12.7 371:13.5 363:14.8 355:14.9 347:15.6 339:17.7 331:18.7 323:22.8 1134:A80 1129:A36 1122:A69 1117:A68 1112:A28 1105:A74 1100:A33 1095:A32 1090:A31 1085:A30 1080:A29 1075:A19 1070:A11 1063:A66 1058:A43 1053:A34 1048:A26 1043:A25 1038:A10 1031:A24 1026:A23 932:PMC 924:doi 885:doi 830:doi 802:HIV 763:1.0 755:1.0 747:1.0 739:1.1 731:1.1 723:1.2 715:1.2 707:1.3 699:1.3 691:1.4 683:1.4 675:1.4 667:1.5 659:1.5 651:1.5 643:1.6 635:1.6 627:1.7 619:1.9 611:1.9 603:1.9 595:2.0 587:2.0 579:2.3 571:2.5 563:2.9 555:3.7 547:3.9 539:4.0 531:4.5 523:4.6 515:5.4 507:5.5 499:5.5 491:5.8 483:6.1 475:6.7 467:6.8 459:7.1 451:7.5 443:8.1 435:8.2 427:8.9 419:9.4 411:9.5 244:A23 206:*23 199:B2M 195:*23 170:EBI 146:A23 84:αβ 1151:: 1021:A9 1016:A3 1011:A2 1006:A1 940:. 930:. 920:76 918:. 914:. 891:. 881:61 879:. 860:- 836:. 826:11 824:. 276:95 265:% 250:24 223:. 37:, 979:e 972:t 965:v 948:. 926:: 899:. 887:: 844:. 832:: 280:1 262:% 248:A 104:2 102:β 71:/ 39:A 33:(

Index

History and naming of human leukocyte antigens
MHC Class I
A

Protein
transmembrane receptor
ligand
Structure
heterodimer
Subunits
HLA-A
β2-microglobulin
*2301
IMGT/HLA
EBI
human leukocyte antigen
serotype
HLA-A
B2M
locus
split antigen
broad antigen
HLA-A9
HLA-A24
Freq.
Allele frequencies
HIV
doi
10.1111/j.1399-0039.1978.tb01233.x
PMID

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