32:
67:
169:, with rare mitoses. These cells are arranged in short fascicles which split and merge, giving the appearance of "fish bone" known as a herringbone pattern. Poorly differentiated tumors consist in more atypical cells, pleomorphic, giant cells, multinucleated, numerous atypical mitoses and reduced collagen production. Presence of immature blood vessels (sarcomatous vessels lacking endothelial cells) favors the bloodstream metastasizing. There are many tumors in the differential diagnosis, including spindle cell
230:
272:
Bostock DE, et al. performed a study of cats that had fibrosarcomas excised and were followed for a minimum of three years, or until death. Two factors, tumor site and mitotic index, were found to be of prognostic significance, but tumor size, duration of growth, and histologic appearance were not.
273:
Following removal of fibrosarcomas from the flank in six cats, none died as a result of the tumor but 24 of 35 (70%) cats with fibrosarcoma in the skin of the head, back, or limbs were euthanized because of local recurrence, usually within nine months of surgery.
411:
El
Demellawy D, Cundiff CA, Nasr A, Ozolek JA, Elawabdeh N, Caltharp SA, Masoudian P, Sullivan KJ, de Nanassy J, Shehata BM (2016). "Congenital mesoblastic nephroma: a study of 19 cases using immunohistochemistry and ETV6-NTRK3 fusion gene rearrangement".
104:. Fibrosarcomas mainly arise in people between the ages of 25 and 79. It originates in fibrous tissues of the bone and invades long or flat bones such as the femur, tibia, and mandible. It also involves the periosteum and overlying muscle.
153:. Indeed, mesoblastic nephroma and congenital infantile sarcoma appear to be the same disease with the exception that mesoblastic lymphoma originates in the kidney whereas congenital infantile sarcoma originates in non-renal tissues.
129:) is usually congenital. Infants presenting with this fibrosarcoma usually do so in the first two years of their life. Cytogenetically, congenital infantile fibrosarcoma is characterized by the majority of cases having a
375:
Walther C, Nilsson J, von
Steyern FV, Wiebe T, Bauer HC, Nord KH, Gisselsson D, Domanski HA, Mandahl N, Mertens F (2013). "Cytogenetic and single nucleotide polymorphism array findings in soft tissue tumors in infants".
698:
606:
165:: low grade (differentiated), intermediate malignancy and high malignancy (anaplastic). Depending on this differentiation, tumour cells may resemble mature fibroblasts (spindle-shaped), secreting
117:
Individuals presenting with fibrosarcoma are usually adults thirty to fifty-five years old, often presenting with pain. Among adults, fibrosarcomas develop equally in men and women.
803:
1338:
718:
1358:
1481:
496:
Ud Din N, Minhas K, Shamim MS, Mushtaq N, Fadoo Z (2015). "Congenital (infantile) fibrosarcoma of the scalp: a case series and review of literature".
1779:
796:
1789:
789:
1474:
245:
Fibrosarcoma occurs most frequently in the mouth in dogs. The tumor is locally invasive, and often recurs following surgery.
607:"Merial Launches Oncept IL-2, The First Veterinary Immunotherapeutic Product In Europe For The Management Of Cancer In Pets"
1159:
1006:
842:
1467:
351:
327:
919:
590:
1410:
1528:
1178:
887:
287:
137:, plus individual cases exhibiting trisomy for chromosomes 8, 11, 17, or 20. The histology, association with the
954:
939:
934:
302:
190:
1052:
959:
186:
1353:
1343:
1064:
133:
between chromosomes 12 and 15 (notated as t(12;15)(p13;q25)) that results in formation of the fusion gene,
1001:
769:
539:
282:
141:
fusion gene as well as certain chromosome trisomies, and the distribution of markers for cell type (i.e.
1629:
1281:
857:
632:
Bostock, D. E.; Dye, M. T. (1979-10-01). "Prognosis after surgical excision of fibrosarcomas in cats".
262:
162:
31:
1405:
1293:
1074:
292:
130:
66:
1725:
944:
729:
1390:
449:"Congenital mesoblastic nephroma: Clinical analysis of eight cases and a review of the literature"
1799:
1794:
1617:
1372:
1130:
974:
914:
866:
174:
1671:
1533:
1208:
1059:
1016:
1011:
1653:
1634:
781:
1395:
1240:
964:
892:
202:
150:
8:
1646:
1385:
1311:
1193:
993:
969:
929:
924:
837:
43:
1348:
1323:
1286:
1183:
1152:
1116:
949:
723:
521:
473:
448:
1663:
1448:
1420:
1328:
1188:
979:
812:
649:
641:
586:
513:
478:
429:
393:
307:
246:
101:
89:
derived from fibrous connective tissue and characterized by the presence of immature
55:
525:
389:
1784:
1612:
1511:
1277:
1173:
1111:
1047:
505:
468:
460:
421:
385:
178:
1707:
1567:
1495:
1400:
1264:
1092:
734:
425:
1459:
675:
269:
launched Oncept IL-2 in Europe for the management of such feline fibrosarcomas.
1717:
1641:
1624:
1425:
1415:
1333:
1318:
1253:
1164:
1102:
1082:
182:
509:
1773:
1572:
1538:
645:
214:
707:
253:
are also used in treatment. Fibrosarcoma is also a rare bone tumor in dogs.
1699:
1591:
1581:
1521:
1443:
1087:
989:
906:
847:
670:
517:
482:
433:
397:
250:
229:
146:
47:
1607:
1603:
1435:
1273:
1147:
1142:
1042:
816:
653:
464:
210:
93:
90:
83:
690:
1559:
1550:
1516:
1491:
1380:
1229:
149:) within this tumor are similar to those found in the cellular form of
97:
39:
580:
1746:
1690:
1599:
1503:
1306:
1249:
1198:
740:
261:
In cats, fibrosarcoma occurs on the skin. It is also the most common
142:
80:
1754:
819:
764:
206:
170:
166:
60:
1577:
902:
875:
823:
745:
671:
Fibrosarcoma of Bone: Review of a Rare
Primary Malignancy of Bone
297:
1138:
1038:
1030:
702:
266:
86:
811:
374:
1225:
410:
218:
711:
495:
233:
1339:
Multiple cutaneous and uterine leiomyomatosis syndrome
634:
Journal of the
American Veterinary Medical Association
680:
1489:
581:Ettinger, Stephen J.; Feldman, Edward C. (1995).
447:Wang ZP, Li K, Dong KR, Xiao XM, Zheng S (2014).
1771:
576:
574:
446:
1475:
797:
571:
201:Ancillary testing for fibrosarcoma includes
489:
440:
404:
368:
161:The tumor may present different degrees of
16:Malignant tumors composed of fibrous tissue
1482:
1468:
804:
790:
631:
65:
30:
472:
1745:
583:Textbook of Veterinary Internal Medicine
567:. Elsevier Health Sciences. p. 414.
228:
585:(4th ed.). W.B. Saunders Company.
125:In infants, fibrosarcoma (often termed
1772:
562:
1463:
785:
540:"Oral Tumors in Dogs - Fibrosarcomas"
1780:Connective and soft tissue neoplasms
1790:Osseous and chondromatous neoplasia
843:Desmoplastic small-round-cell tumor
236:after fourth fibrosarcoma operation
13:
14:
1811:
920:Aggressive infantile fibromatosis
664:
127:congenital infantile fibrosarcoma
120:
1411:Clear-cell sarcoma of the kidney
46:as may be seen in fibrosarcoma.
1529:Primitive neuroectodermal tumor
1179:Intradermal spindle cell lipoma
888:Dermatofibrosarcoma protuberans
625:
599:
390:10.1016/j.cancergen.2013.06.004
288:Dermatofibrosarcoma protuberans
107:
1007:Malignant fibrous histiocytoma
955:Infantile digital fibromatosis
940:Familial myxovascular fibromas
935:Diffuse infantile fibromatosis
563:Fossum, Theresa Welch (2013).
556:
532:
344:
320:
303:Malignant fibrous histiocytoma
191:biphenotypic sinonasal sarcoma
1:
1053:Superficial acral fibromyxoma
960:Juvenile hyaline fibromatosis
565:Small Animal Surgery Textbook
313:
224:
187:peripheral nerve sheath tumor
112:
1354:Solitary cutaneous leiomyoma
1344:Multiple cutaneous leiomyoma
1065:Ossifying fibromyxoid tumour
426:10.1016/j.pathol.2015.11.007
196:
156:
79:(fibroblastic sarcoma) is a
7:
1002:Benign fibrous histiocytoma
283:Benign fibrous histiocytoma
276:
10:
1816:
1630:Mesenchymal chondrosarcoma
1282:Embryonal rhabdomyosarcoma
858:Connective tissue neoplasm
263:vaccine-associated sarcoma
1738:
1716:
1698:
1689:
1662:
1590:
1558:
1549:
1502:
1434:
1406:Malignant rhabdoid tumour
1373:Complex mixed and stromal
1371:
1302:
1294:Alveolar rhabdomyosarcoma
1262:
1238:
1216:
1207:
1129:
1101:
1073:
1029:
988:
901:
874:
865:
856:
830:
755:
684:
510:10.1007/s00381-015-2824-1
293:Fibrous connective tissue
54:
38:
29:
24:
1726:Giant-cell tumor of bone
945:Fibroma of tendon sheath
1618:Extraskeletal chondroma
975:Oral submucous fibrosis
915:Aggressive fibromatosis
831:Not otherwise specified
256:
240:
175:squamous cell carcinoma
1017:Solitary fibrous tumor
1012:Atypical fibroxanthoma
498:Child's Nervous System
237:
1654:Chondromyxoid fibroma
1635:Myxoid chondrosarcoma
1391:Mixed Müllerian tumor
232:
42:of a tumour with the
1396:Mesoblastic nephroma
965:Plantar fibromatosis
893:Desmoplastic fibroma
465:10.3892/ol.2014.2489
151:mesoblastic nephroma
96:or undifferentiated
1647:Osteochondromatosis
1386:Pleomorphic adenoma
1194:Spindle cell lipoma
994:histiocytic sarcoma
970:Pleomorphic fibroma
930:Collagenous fibroma
925:Aponeurotic fibroma
838:Soft-tissue sarcoma
613:. February 23, 2016
100:spindle cells in a
44:herringbone pattern
1349:Neural fibrolipoma
1324:Angiolipoleiomyoma
1287:Sarcoma botryoides
1184:Pleomorphic lipoma
1153:Myxoid liposarcoma
1117:Clear-cell sarcoma
950:Fibromatosis colli
756:External resources
676:Atlas of Pathology
238:
217:are negative, and
1767:
1766:
1763:
1762:
1734:
1733:
1685:
1684:
1672:Ossifying fibroma
1457:
1456:
1449:Adenomatoid tumor
1421:Pancreatoblastoma
1367:
1366:
1329:Genital leiomyoma
1189:Lipoblastomatosis
1125:
1124:
1025:
1024:
980:Pachydermodactyly
779:
778:
611:www.vetclick.com/
308:Neurofibrosarcoma
247:Radiation therapy
102:storiform pattern
74:
73:
19:Medical condition
1807:
1743:
1742:
1696:
1695:
1613:Enchondromatosis
1556:
1555:
1512:Multiple myeloma
1484:
1477:
1470:
1461:
1460:
1278:rhabdomyosarcoma
1267:
1243:
1219:
1214:
1213:
1174:Chondroid lipoma
1112:Synovial sarcoma
1048:Cutaneous myxoma
872:
871:
863:
862:
806:
799:
792:
783:
782:
682:
681:
658:
657:
629:
623:
622:
620:
618:
603:
597:
596:
578:
569:
568:
560:
554:
553:
551:
550:
536:
530:
529:
493:
487:
486:
476:
459:(5): 2007–2011.
453:Oncology Letters
444:
438:
437:
408:
402:
401:
384:(7–8): 299–303.
372:
366:
365:
363:
362:
356:encyclopedia.com
348:
342:
341:
339:
338:
332:encyclopedia.com
324:
179:synovial sarcoma
70:
69:
34:
22:
21:
1815:
1814:
1810:
1809:
1808:
1806:
1805:
1804:
1770:
1769:
1768:
1759:
1730:
1712:
1708:Chondroblastoma
1681:
1658:
1586:
1568:Osteoid osteoma
1545:
1498:
1488:
1458:
1453:
1430:
1363:
1298:
1265:Skeletal muscle
1263:
1258:
1239:
1234:
1217:
1203:
1121:
1097:
1093:Phyllodes tumor
1075:Fibroepithelial
1069:
1021:
984:
897:
852:
826:
810:
780:
775:
774:
751:
750:
693:
667:
662:
661:
630:
626:
616:
614:
605:
604:
600:
593:
579:
572:
561:
557:
548:
546:
538:
537:
533:
494:
490:
445:
441:
409:
405:
378:Cancer Genetics
373:
369:
360:
358:
350:
349:
345:
336:
334:
326:
325:
321:
316:
279:
259:
243:
227:
199:
173:, spindle cell
163:differentiation
159:
123:
115:
110:
64:
20:
17:
12:
11:
5:
1813:
1803:
1802:
1800:Cancer in dogs
1797:
1795:Cancer in cats
1792:
1787:
1782:
1765:
1764:
1761:
1760:
1758:
1757:
1751:
1749:
1740:
1736:
1735:
1732:
1731:
1729:
1728:
1722:
1720:
1714:
1713:
1711:
1710:
1704:
1702:
1693:
1687:
1686:
1683:
1682:
1680:
1679:
1674:
1668:
1666:
1660:
1659:
1657:
1656:
1651:
1650:
1649:
1642:Osteochondroma
1639:
1638:
1637:
1632:
1625:Chondrosarcoma
1622:
1621:
1620:
1615:
1596:
1594:
1588:
1587:
1585:
1584:
1575:
1570:
1564:
1562:
1553:
1547:
1546:
1544:
1543:
1542:
1541:
1536:
1526:
1525:
1524:
1514:
1508:
1506:
1500:
1499:
1487:
1486:
1479:
1472:
1464:
1455:
1454:
1452:
1451:
1446:
1440:
1438:
1432:
1431:
1429:
1428:
1426:Carcinosarcoma
1423:
1418:
1416:Hepatoblastoma
1413:
1408:
1403:
1398:
1393:
1388:
1383:
1377:
1375:
1369:
1368:
1365:
1364:
1362:
1361:
1356:
1351:
1346:
1341:
1336:
1334:Leiomyosarcoma
1331:
1326:
1321:
1319:Angioleiomyoma
1316:
1315:
1314:
1303:
1300:
1299:
1297:
1296:
1291:
1290:
1289:
1270:
1268:
1260:
1259:
1257:
1256:
1254:leiomyosarcoma
1246:
1244:
1236:
1235:
1233:
1232:
1222:
1220:
1211:
1205:
1204:
1202:
1201:
1196:
1191:
1186:
1181:
1176:
1170:
1169:
1168:
1167:
1165:Angiomyolipoma
1157:
1156:
1155:
1150:
1135:
1133:
1127:
1126:
1123:
1122:
1120:
1119:
1114:
1108:
1106:
1099:
1098:
1096:
1095:
1090:
1085:
1083:Brenner tumour
1079:
1077:
1071:
1070:
1068:
1067:
1062:
1057:
1056:
1055:
1050:
1035:
1033:
1027:
1026:
1023:
1022:
1020:
1019:
1014:
1009:
1004:
998:
996:
986:
985:
983:
982:
977:
972:
967:
962:
957:
952:
947:
942:
937:
932:
927:
922:
917:
911:
909:
899:
898:
896:
895:
890:
884:
882:
869:
860:
854:
853:
851:
850:
845:
840:
834:
832:
828:
827:
809:
808:
801:
794:
786:
777:
776:
773:
772:
760:
759:
757:
753:
752:
749:
748:
737:
726:
715:
694:
689:
688:
686:
685:Classification
679:
678:
673:
666:
665:External links
663:
660:
659:
640:(7): 727–728.
624:
598:
591:
570:
555:
531:
504:(11): 2145–9.
488:
439:
403:
367:
352:"Fibrosarcoma"
343:
328:"fibrosarcoma"
318:
317:
315:
312:
311:
310:
305:
300:
295:
290:
285:
278:
275:
258:
255:
242:
239:
226:
223:
198:
195:
183:leiomyosarcoma
158:
155:
122:
121:Infantile-type
119:
114:
111:
109:
106:
72:
71:
58:
52:
51:
36:
35:
27:
26:
18:
15:
9:
6:
4:
3:
2:
1812:
1801:
1798:
1796:
1793:
1791:
1788:
1786:
1783:
1781:
1778:
1777:
1775:
1756:
1753:
1752:
1750:
1748:
1744:
1741:
1737:
1727:
1724:
1723:
1721:
1719:
1715:
1709:
1706:
1705:
1703:
1701:
1697:
1694:
1692:
1688:
1678:
1675:
1673:
1670:
1669:
1667:
1665:
1661:
1655:
1652:
1648:
1645:
1644:
1643:
1640:
1636:
1633:
1631:
1628:
1627:
1626:
1623:
1619:
1616:
1614:
1611:
1610:
1609:
1605:
1601:
1598:
1597:
1595:
1593:
1589:
1583:
1579:
1576:
1574:
1573:Osteoblastoma
1571:
1569:
1566:
1565:
1563:
1561:
1557:
1554:
1552:
1548:
1540:
1539:Ewing sarcoma
1537:
1535:
1532:
1531:
1530:
1527:
1523:
1520:
1519:
1518:
1515:
1513:
1510:
1509:
1507:
1505:
1501:
1497:
1493:
1485:
1480:
1478:
1473:
1471:
1466:
1465:
1462:
1450:
1447:
1445:
1442:
1441:
1439:
1437:
1433:
1427:
1424:
1422:
1419:
1417:
1414:
1412:
1409:
1407:
1404:
1402:
1399:
1397:
1394:
1392:
1389:
1387:
1384:
1382:
1379:
1378:
1376:
1374:
1370:
1360:
1357:
1355:
1352:
1350:
1347:
1345:
1342:
1340:
1337:
1335:
1332:
1330:
1327:
1325:
1322:
1320:
1317:
1313:
1310:
1309:
1308:
1305:
1304:
1301:
1295:
1292:
1288:
1285:
1284:
1283:
1279:
1275:
1272:
1271:
1269:
1266:
1261:
1255:
1251:
1248:
1247:
1245:
1242:
1241:Smooth muscle
1237:
1231:
1227:
1224:
1223:
1221:
1215:
1212:
1210:
1206:
1200:
1197:
1195:
1192:
1190:
1187:
1185:
1182:
1180:
1177:
1175:
1172:
1171:
1166:
1163:
1162:
1161:
1158:
1154:
1151:
1149:
1146:
1145:
1144:
1140:
1137:
1136:
1134:
1132:
1128:
1118:
1115:
1113:
1110:
1109:
1107:
1104:
1100:
1094:
1091:
1089:
1086:
1084:
1081:
1080:
1078:
1076:
1072:
1066:
1063:
1061:
1058:
1054:
1051:
1049:
1046:
1045:
1044:
1040:
1037:
1036:
1034:
1032:
1028:
1018:
1015:
1013:
1010:
1008:
1005:
1003:
1000:
999:
997:
995:
991:
987:
981:
978:
976:
973:
971:
968:
966:
963:
961:
958:
956:
953:
951:
948:
946:
943:
941:
938:
936:
933:
931:
928:
926:
923:
921:
918:
916:
913:
912:
910:
908:
904:
900:
894:
891:
889:
886:
885:
883:
881:
877:
873:
870:
868:
864:
861:
859:
855:
849:
846:
844:
841:
839:
836:
835:
833:
829:
825:
821:
818:
814:
807:
802:
800:
795:
793:
788:
787:
784:
771:
767:
766:
762:
761:
758:
754:
747:
743:
742:
738:
736:
732:
731:
727:
725:
721:
720:
716:
713:
709:
705:
704:
700:
696:
695:
692:
687:
683:
677:
674:
672:
669:
668:
655:
651:
647:
643:
639:
635:
628:
612:
608:
602:
594:
592:0-7216-6795-3
588:
584:
577:
575:
566:
559:
545:
544:vca_corporate
541:
535:
527:
523:
519:
515:
511:
507:
503:
499:
492:
484:
480:
475:
470:
466:
462:
458:
454:
450:
443:
435:
431:
427:
423:
419:
415:
407:
399:
395:
391:
387:
383:
379:
371:
357:
353:
347:
333:
329:
323:
319:
309:
306:
304:
301:
299:
296:
294:
291:
289:
286:
284:
281:
280:
274:
270:
268:
264:
254:
252:
248:
235:
231:
222:
221:is variable.
220:
216:
212:
209:is positive,
208:
204:
194:
192:
188:
184:
180:
176:
172:
168:
164:
154:
152:
148:
144:
140:
136:
132:
131:translocation
128:
118:
105:
103:
99:
95:
92:
91:proliferating
88:
85:
82:
78:
68:
62:
59:
57:
53:
49:
48:H&E stain
45:
41:
37:
33:
28:
23:
1700:Chondroblast
1677:Fibrosarcoma
1676:
1592:Chondroblast
1582:osteosarcoma
1534:Ewing family
1522:Adamantinoma
1444:Mesothelioma
1401:Wilms' tumor
1088:Fibroadenoma
990:Histiocytoma
907:fibromatosis
880:fibrosarcoma
879:
848:Skin sarcoma
763:
739:
728:
717:
697:
637:
633:
627:
617:February 23,
615:. Retrieved
610:
601:
582:
564:
558:
547:. Retrieved
543:
534:
501:
497:
491:
456:
452:
442:
420:(1): 47–50.
417:
413:
406:
381:
377:
370:
359:. Retrieved
355:
346:
335:. Retrieved
331:
322:
271:
260:
251:chemotherapy
244:
200:
185:, malignant
160:
147:Beta-catenin
138:
134:
126:
124:
116:
108:Presentation
77:Fibrosarcoma
76:
75:
25:Fibrosarcoma
1608:enchondroma
1604:ecchondroma
1490:Tumours of
1436:Mesothelial
1274:Rhabdomyoma
1148:Myelolipoma
1143:liposarcoma
1060:Angiomyxoma
1043:myxosarcoma
867:Fibromatous
817:soft tissue
265:. In 2014,
211:cytokeratin
94:fibroblasts
84:mesenchymal
1774:Categories
1560:Osteoblast
1551:Metaphysis
1381:Adenomyoma
1230:myosarcoma
1131:Lipomatous
1031:Myxomatous
813:Connective
549:2019-05-29
361:2021-10-30
337:2021-10-30
314:References
225:In animals
139:ETV6-NRTK3
135:ETV6-NTRK3
113:Adult-type
98:anaplastic
40:Micrograph
1747:Notochord
1691:Epiphysis
1600:Chondroma
1517:Epithelia
1504:Diaphysis
1496:cartilage
1312:Cutaneous
1307:Leiomyoma
1250:Leiomyoma
1209:Myomatous
1199:Hibernoma
741:SNOMED CT
646:0003-1488
414:Pathology
197:Diagnosis
157:Pathology
143:cyclin D1
81:malignant
56:Specialty
1755:Chordoma
1103:Synovial
824:sarcomas
765:Orphanet
746:53654007
714:C49.M42)
526:25198570
518:26206116
483:25295083
434:27020209
398:23938179
277:See also
207:vimentin
205:, where
171:melanoma
167:collagen
61:Oncology
1785:Sarcoma
1718:Myeloid
1664:Fibrous
1578:Osteoma
1218:General
903:Fibroma
876:Fibroma
735:D005354
724:M8810/3
474:4186628
298:Fibroma
1160:PEComa
1139:Lipoma
1039:Myxoma
820:tumors
654:528318
652:
644:
589:
524:
516:
481:
471:
432:
396:
267:Merial
87:tumour
63:
1739:Other
1359:STUMP
1226:Myoma
1105:-like
719:ICD-O
522:S2CID
219:actin
1494:and
1492:bone
822:and
770:2030
730:MeSH
712:ILDS
650:PMID
642:ISSN
619:2016
587:ISBN
514:PMID
479:PMID
430:PMID
394:PMID
257:Cats
249:and
241:Dogs
215:S100
213:and
189:and
145:and
708:C49
699:ICD
638:175
506:doi
469:PMC
461:doi
422:doi
386:doi
382:206
234:Cat
203:IHC
1776::
1280::
768::
744::
733::
722::
706::
703:10
648:.
636:.
609:.
573:^
542:.
520:.
512:.
502:31
500:.
477:.
467:.
455:.
451:.
428:.
418:48
416:.
392:.
380:.
354:.
330:.
193:.
181:,
177:,
1606:/
1602:/
1580:/
1483:e
1476:t
1469:v
1276:/
1252:/
1228:/
1141:/
1041:/
992:/
905:/
878:/
815:/
805:e
798:t
791:v
710:(
701:-
691:D
656:.
621:.
595:.
552:.
528:.
508::
485:.
463::
457:8
436:.
424::
400:.
388::
364:.
340:.
50:.
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
