1584:
248:
271:
280:
257:
1065:
1011:
150:
426:
673:
834:
491:
930:
641:
658:
160:
905:
210:
819:
920:
914:
715:
465:
763:
1303:
874:
663:
981:
869:
173:
790:
700:
653:
205:
1459:
1212:
1153:
239:
1257:
824:
814:
1217:
1109:
734:
224:
195:, removes phosphate groups from many types of molecules, including nucleotides, proteins, and alkaloids.
1574:
803:
799:
795:
711:
544:
182:
1560:
1547:
1534:
1521:
1508:
1495:
1482:
1444:
971:
527:
1619:
1454:
1408:
1351:
719:
568:
482:
70:
1356:
588:
458:
333:
320:
307:
1144:
783:
411:
1377:
1296:
1079:
976:
768:
729:
593:
515:
364:
303:
121:
1449:
1262:
1097:
1092:
1025:
685:
510:
192:
109:
8:
1604:
1413:
1117:
1087:
891:
886:
810:
746:
532:
47:
1346:
1250:
1102:
583:
573:
451:
406:
1051:
996:
964:
839:
558:
354:
289:
198:
74:
51:
1392:
1387:
1361:
1289:
1127:
707:
612:
607:
563:
369:
329:
316:
202:
113:
99:
55:
1614:
1609:
1439:
1423:
1336:
1229:
1043:
959:
954:
949:
862:
857:
617:
495:
438:
396:
391:
228:
443:
1588:
1477:
1418:
1202:
1197:
1192:
578:
553:
549:
522:
505:
138:
104:
92:
1598:
1382:
1341:
943:
852:
602:
116:
1331:
1070:
1001:
724:
645:
358:
350:
342:
293:
155:
125:
27:
16:
Class of enzymes which split esters into an acid and alcohol via hydrolysis
227:(3.1.3.11), converts fructose-1,6-bisphosphate to fructose-6-phosphate in
1555:
1490:
1326:
1245:
1016:
910:
773:
739:
677:
285:
178:
20:
1222:
261:
214:
59:
1529:
1503:
1135:
934:
847:
474:
186:
63:
1583:
1180:
1175:
1170:
991:
626:
416:
1187:
1165:
1160:
778:
1542:
1312:
1207:
1140:
1033:
631:
539:
421:
386:
96:
69:
A wide range of different esterases exist that differ in their
35:
1516:
1149:
900:
896:
401:
129:
39:
881:
758:
751:
695:
690:
43:
1281:
1572:
80:
427:
Asymmetric ester hydrolysis with pig-liver esterase
769:Fructose 6-P,2-kinase:fructose 2,6-bisphosphatase
473:
1596:
1297:
459:
124:, broad substrate specificity, found in the
1304:
1290:
466:
452:
659:Ubiquitin carboxy-terminal hydrolase L1
161:Ubiquitin carboxy-terminal hydrolase L1
1597:
211:cGMP specific phosphodiesterase type 5
1285:
1239:either deoxy- or ribo-
447:
141:(EC 3.1.1.11), clarifies fruit juices
820:Protein serine/threonine phosphatase
921:Cyclic nucleotide phosphodiesterase
915:Clostridium perfringens alpha toxin
716:Tartrate-resistant acid phosphatase
13:
764:Pyruvate dehydrogenase phosphatase
345:active with either ribo- or deoxy-
249:Triphosphoric monoester hydrolases
14:
1631:
664:4-hydroxybenzoyl-CoA thioesterase
432:
272:Diphosphoric monoester hydrolases
81:EC classification/list of enzymes
77:, and their biological function.
1582:
982:N-acetylglucosamine-6-sulfatase
870:Sphingomyelin phosphodiesterase
174:Phosphoric monoester hydrolases
791:Inositol-phosphate phosphatase
654:Palmitoyl protein thioesterase
281:Phosphoric triester hydrolases
89:: Carboxylic ester hydrolases
62:(and as such, it is a type of
1:
1154:RNA-induced silencing complex
240:Phosphoric diester hydrolases
1258:Serratia marcescens nuclease
825:Dual-specificity phosphatase
815:Protein tyrosine phosphatase
7:
1311:
735:Fructose 1,6-bisphosphatase
380:
10:
1636:
183:phosphoric acid monoesters
18:
1468:
1460:Michaelis–Menten kinetics
1432:
1401:
1370:
1319:
1238:
1126:
1078:
1064:
1042:
1024:
1010:
990:
972:Galactosamine-6 sulfatase
929:
833:
672:
640:
528:6-phosphogluconolactonase
490:
258:Sulfuric ester hydrolases
181:(EC 3.1.3.x), hydrolyses
95:(EC 3.1.1.6), splits off
1352:Diffusion-limited enzyme
720:Purple acid phosphatases
19:Not to be confused with
225:Fructose bisphosphatase
201:(PDE), inactivates the
1145:Microprocessor complex
784:Beta-propeller phytase
412:Hemagglutinin esterase
374:either deoxy- or ribo-
1445:Eadie–Hofstee diagram
1378:Allosteric regulation
1080:Endodeoxyribonuclease
977:Iduronate-2-sulfatase
730:Glucose 6-phosphatase
516:Butyrylcholinesterase
365:Endodeoxyribonuclease
304:Exodeoxyribonucleases
151:Thiolester hydrolases
1455:Lineweaver–Burk plot
1263:Micrococcal nuclease
1098:Deoxyribonuclease IV
1093:Deoxyribonuclease II
1026:Exodeoxyribonuclease
686:Alkaline phosphatase
511:Acetylcholinesterase
334:3'-phosphomonoesters
321:5'-phosphomonoesters
308:5'-phosphomonoesters
193:Alkaline phosphatase
122:Pseudocholinesterase
110:Acetylcholinesterase
1118:UvrABC endonuclease
1088:Deoxyribonuclease I
811:Protein phosphatase
747:Protein phosphatase
545:Bile salt-dependent
533:PAF acetylhydrolase
439:Enzyme nomenclature
189:ion and an alcohol
73:specificity, their
1414:Enzyme superfamily
1347:Enzyme promiscuity
1251:Mung bean nuclease
1110:Restriction enzyme
1103:Restriction enzyme
407:Leukocyte esterase
355:deoxyribonucleases
290:deoxyribonucleases
213:, is inhibited by
112:, inactivates the
1570:
1569:
1279:
1278:
1275:
1274:
1271:
1270:
1060:
1059:
1052:Oligonucleotidase
997:deoxyribonuclease
965:Steroid sulfatase
840:Phosphodiesterase
569:Hormone-sensitive
199:Phosphodiesterase
75:protein structure
52:chemical reaction
1627:
1587:
1586:
1578:
1450:Hanes–Woolf plot
1393:Enzyme activator
1388:Enzyme inhibitor
1362:Enzyme catalysis
1306:
1299:
1292:
1283:
1282:
1128:Endoribonuclease
1114:
1108:
1076:
1075:
1022:
1021:
1008:
1007:
708:Acid phosphatase
589:Monoacylglycerol
499:ester hydrolases
468:
461:
454:
445:
444:
370:Endoribonuclease
330:Exoribonucleases
317:Exoribonucleases
203:second messenger
114:neurotransmitter
1635:
1634:
1630:
1629:
1628:
1626:
1625:
1624:
1620:Neurophysiology
1595:
1594:
1593:
1581:
1573:
1571:
1566:
1478:Oxidoreductases
1464:
1440:Enzyme kinetics
1428:
1424:List of enzymes
1397:
1366:
1337:Catalytic triad
1315:
1310:
1280:
1267:
1234:
1122:
1112:
1106:
1069:
1056:
1044:Exoribonuclease
1038:
1015:
999:
995:
986:
960:Arylsulfatase L
955:Arylsulfatase B
950:Arylsulfatase A
925:
838:
829:
668:
636:
498:
486:
472:
435:
397:Carboxylic acid
392:List of enzymes
383:
229:gluconeogenesis
83:
24:
17:
12:
11:
5:
1633:
1623:
1622:
1617:
1612:
1607:
1592:
1591:
1568:
1567:
1565:
1564:
1551:
1538:
1525:
1512:
1499:
1486:
1472:
1470:
1466:
1465:
1463:
1462:
1457:
1452:
1447:
1442:
1436:
1434:
1430:
1429:
1427:
1426:
1421:
1416:
1411:
1405:
1403:
1402:Classification
1399:
1398:
1396:
1395:
1390:
1385:
1380:
1374:
1372:
1368:
1367:
1365:
1364:
1359:
1354:
1349:
1344:
1339:
1334:
1329:
1323:
1321:
1317:
1316:
1309:
1308:
1301:
1294:
1286:
1277:
1276:
1273:
1272:
1269:
1268:
1266:
1265:
1260:
1255:
1254:
1253:
1242:
1240:
1236:
1235:
1233:
1232:
1227:
1226:
1225:
1220:
1215:
1210:
1200:
1195:
1190:
1185:
1184:
1183:
1178:
1173:
1168:
1158:
1157:
1156:
1147:
1132:
1130:
1124:
1123:
1121:
1120:
1115:
1100:
1095:
1090:
1084:
1082:
1073:
1062:
1061:
1058:
1057:
1055:
1054:
1048:
1046:
1040:
1039:
1037:
1036:
1030:
1028:
1019:
1005:
988:
987:
985:
984:
979:
974:
969:
968:
967:
962:
957:
952:
939:
937:
927:
926:
924:
923:
918:
908:
903:
894:
889:
884:
879:
878:
877:
867:
866:
865:
860:
850:
844:
842:
831:
830:
828:
827:
822:
817:
808:
807:
806:
788:
787:
786:
776:
771:
766:
761:
756:
755:
754:
744:
743:
742:
732:
727:
722:
705:
704:
703:
698:
693:
682:
680:
670:
669:
667:
666:
661:
656:
650:
648:
638:
637:
635:
634:
629:
623:
622:
621:
620:
615:
610:
599:
598:
597:
596:
594:Diacylglycerol
591:
586:
581:
576:
571:
566:
561:
556:
547:
536:
535:
530:
525:
523:Pectinesterase
520:
519:
518:
513:
506:Cholinesterase
502:
500:
488:
487:
471:
470:
463:
456:
448:
442:
441:
434:
433:External links
431:
430:
429:
424:
419:
414:
409:
404:
399:
394:
389:
382:
379:
378:
377:
376:
375:
372:
367:
348:
347:
346:
336:
323:
310:
283:
274:
265:
251:
242:
233:
232:
231:
222:
221:
220:
219:
218:
196:
167:
166:
165:
164:
163:
144:
143:
142:
139:Pectinesterase
136:
135:
134:
133:
132:
119:
105:Cholinesterase
93:Acetylesterase
82:
79:
34:is a class of
15:
9:
6:
4:
3:
2:
1632:
1621:
1618:
1616:
1613:
1611:
1608:
1606:
1603:
1602:
1600:
1590:
1585:
1580:
1579:
1576:
1562:
1558:
1557:
1552:
1549:
1545:
1544:
1539:
1536:
1532:
1531:
1526:
1523:
1519:
1518:
1513:
1510:
1506:
1505:
1500:
1497:
1493:
1492:
1487:
1484:
1480:
1479:
1474:
1473:
1471:
1467:
1461:
1458:
1456:
1453:
1451:
1448:
1446:
1443:
1441:
1438:
1437:
1435:
1431:
1425:
1422:
1420:
1419:Enzyme family
1417:
1415:
1412:
1410:
1407:
1406:
1404:
1400:
1394:
1391:
1389:
1386:
1384:
1383:Cooperativity
1381:
1379:
1376:
1375:
1373:
1369:
1363:
1360:
1358:
1355:
1353:
1350:
1348:
1345:
1343:
1342:Oxyanion hole
1340:
1338:
1335:
1333:
1330:
1328:
1325:
1324:
1322:
1318:
1314:
1307:
1302:
1300:
1295:
1293:
1288:
1287:
1284:
1264:
1261:
1259:
1256:
1252:
1249:
1248:
1247:
1244:
1243:
1241:
1237:
1231:
1228:
1224:
1221:
1219:
1216:
1214:
1211:
1209:
1206:
1205:
1204:
1201:
1199:
1196:
1194:
1191:
1189:
1186:
1182:
1179:
1177:
1174:
1172:
1169:
1167:
1164:
1163:
1162:
1159:
1155:
1151:
1148:
1146:
1142:
1139:
1138:
1137:
1134:
1133:
1131:
1129:
1125:
1119:
1116:
1111:
1104:
1101:
1099:
1096:
1094:
1091:
1089:
1086:
1085:
1083:
1081:
1077:
1074:
1072:
1067:
1063:
1053:
1050:
1049:
1047:
1045:
1041:
1035:
1032:
1031:
1029:
1027:
1023:
1020:
1018:
1013:
1009:
1006:
1003:
998:
993:
989:
983:
980:
978:
975:
973:
970:
966:
963:
961:
958:
956:
953:
951:
948:
947:
946:
945:
944:arylsulfatase
941:
940:
938:
936:
932:
928:
922:
919:
916:
912:
909:
907:
904:
902:
898:
895:
893:
890:
888:
885:
883:
880:
876:
873:
872:
871:
868:
864:
861:
859:
856:
855:
854:
853:Phospholipase
851:
849:
846:
845:
843:
841:
836:
832:
826:
823:
821:
818:
816:
812:
809:
805:
801:
797:
794:
793:
792:
789:
785:
782:
781:
780:
777:
775:
772:
770:
767:
765:
762:
760:
757:
753:
750:
749:
748:
745:
741:
738:
737:
736:
733:
731:
728:
726:
723:
721:
717:
713:
709:
706:
702:
699:
697:
694:
692:
689:
688:
687:
684:
683:
681:
679:
675:
671:
665:
662:
660:
657:
655:
652:
651:
649:
647:
643:
639:
633:
630:
628:
625:
624:
619:
616:
614:
611:
609:
606:
605:
604:
603:Phospholipase
601:
600:
595:
592:
590:
587:
585:
582:
580:
577:
575:
572:
570:
567:
565:
562:
560:
557:
555:
551:
548:
546:
543:
542:
541:
538:
537:
534:
531:
529:
526:
524:
521:
517:
514:
512:
509:
508:
507:
504:
503:
501:
497:
493:
489:
484:
480:
476:
469:
464:
462:
457:
455:
450:
449:
446:
440:
437:
436:
428:
425:
423:
420:
418:
415:
413:
410:
408:
405:
403:
400:
398:
395:
393:
390:
388:
385:
384:
373:
371:
368:
366:
363:
362:
360:
359:ribonucleases
356:
352:
351:Endonucleases
349:
344:
340:
337:
335:
331:
327:
324:
322:
318:
314:
311:
309:
305:
301:
298:
297:
295:
294:ribonucleases
291:
287:
284:
282:
278:
275:
273:
269:
266:
263:
259:
255:
252:
250:
246:
243:
241:
237:
234:
230:
226:
223:
216:
212:
209:
208:
207:
204:
200:
197:
194:
191:
190:
188:
184:
180:
177:
176:
175:
171:
168:
162:
159:
158:
157:
154:
153:
152:
148:
145:
140:
137:
131:
127:
123:
120:
118:
117:acetylcholine
115:
111:
108:
107:
106:
103:
102:
101:
98:
94:
91:
90:
88:
85:
84:
78:
76:
72:
67:
65:
61:
57:
53:
49:
45:
41:
37:
33:
29:
22:
1556:Translocases
1553:
1540:
1527:
1514:
1501:
1491:Transferases
1488:
1475:
1332:Binding site
1113:}}
1107:{{
1071:Endonuclease
1002:ribonuclease
942:
725:Nucleotidase
646:Thioesterase
478:
343:Exonucleases
338:
325:
312:
299:
286:Exonucleases
276:
267:
253:
244:
235:
169:
156:Thioesterase
146:
126:blood plasma
86:
68:
38:that splits
31:
28:biochemistry
25:
1327:Active site
1246:Nuclease S1
1017:Exonuclease
911:Lecithinase
740:Calcineurin
678:Phosphatase
584:Lipoprotein
574:Endothelial
179:Phosphatase
128:and in the
21:Transferase
1605:Hydrolases
1599:Categories
1530:Isomerases
1504:Hydrolases
1371:Regulation
559:Pancreatic
496:Carboxylic
332:producing
319:producing
306:producing
262:sulfatases
215:Sildenafil
60:hydrolysis
1409:EC number
1136:RNase III
994:(includes
935:Sulfatase
848:Autotaxin
712:Prostatic
564:Lysosomal
479:esterases
475:Hydrolase
339:EC 3.1.15
326:EC 3.1.14
313:EC 3.1.13
300:EC 3.1.11
187:phosphate
71:substrate
64:hydrolase
1433:Kinetics
1357:Cofactor
1320:Activity
1230:RNase T1
992:Nuclease
627:Cutinase
417:Nuclease
381:See also
277:EC 3.1.8
268:EC 3.1.7
254:EC 3.1.6
245:EC 3.1.5
236:EC 3.1.4
217:(Viagra)
170:EC 3.1.3
147:EC 3.1.2
87:EC 3.1.1
42:into an
32:esterase
1589:Biology
1543:Ligases
1313:Enzymes
1203:RNase E
1198:RNase Z
1193:RNase A
1188:RNase P
1161:RNase H
779:Phytase
579:Hepatic
554:Lingual
550:Gastric
185:into a
58:called
48:alcohol
46:and an
1615:EC 3.1
1610:Esters
1575:Portal
1517:Lyases
1141:Drosha
1066:3.1.21
1034:RecBCD
1012:3.1.11
632:PETase
540:Lipase
422:Lipase
387:Enzyme
100:groups
97:acetyl
40:esters
36:enzyme
1469:Types
1150:Dicer
1105:;see
931:3.1.6
901:PDE4B
897:PDE4A
835:3.1.4
804:IMPA3
800:IMPA2
796:IMPA1
674:3.1.3
642:3.1.2
492:3.1.1
402:Ester
130:liver
56:water
54:with
50:in a
30:, an
1561:list
1554:EC7
1548:list
1541:EC6
1535:list
1528:EC5
1522:list
1515:EC4
1509:list
1502:EC3
1496:list
1489:EC2
1483:list
1476:EC1
1068:-31:
1014:-16:
1000:and
906:PDE5
892:PDE3
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