111:
936:
36:
570:
28:
44:
1043:
1283:
564:
1105:
809:
78:
routes. Enteral administration involves the esophagus, stomach, and small and large intestines (i.e., the gastrointestinal tract). Methods of administration include oral, sublingual (dissolving the drug under the tongue), and rectal. Parenteral administration is via a peripheral or central vein. In
379:, and therefore, the amount of drug entering the systemic circulation following administration may vary significantly for different individuals and drugs. Rectal administration is not subject to extensive first pass metabolism.
481:
1327:
474:
553:
467:
118:
Enteral administration may be divided into three different categories, depending on the entrance point into the GI tract: oral (by
838:
135:
1421:
447:
114:
A man with a nasogastric tube allowing food and medicine to be delivered through the nose and straight to the stomach
306:
The mechanism for drug absorption from the intestine is for most drugs passive transfer, a few exceptions include
919:
1016:
859:
1390:
1352:
695:
511:
59:
413:
330:
lining the inside of the intestines. The rate at which this happens is largely determined by two factors:
1304:
110:
55:
1332:
901:
315:
1380:
1309:
896:
843:
677:
345:
935:
1299:
673:
388:
1370:
1337:
1291:
1136:
968:
700:
621:
548:
490:
219:
17:
1365:
1319:
1261:
1167:
641:
224:
131:
35:
1375:
1256:
669:
376:
1220:
1065:
983:
928:
848:
833:
636:
190:
88:
8:
1273:
1010:
891:
886:
606:
502:
459:
149:
92:
75:
1347:
1141:
1096:
793:
538:
363:
1197:
1192:
1030:
771:
533:
443:
202:
1131:
335:
327:
319:
1021:
705:
569:
185:
84:
1082:
715:
260:
130:). (Gastric introduction involves the use of a tube through the nasal passage (
96:
43:
27:
1415:
1225:
1147:
1116:
881:
710:
323:
31:
A medical professional demonstrates how to offer oral medication to a dummy.
1266:
1202:
1187:
1162:
1000:
720:
393:
311:
80:
1360:
1248:
1121:
1077:
1055:
1042:
973:
943:
877:
726:
665:
494:
246:
212:
139:
1282:
1244:
1215:
775:
749:
611:
351:
331:
63:
563:
375:
Drugs given by enteral administration may be subjected to significant
854:
744:
596:
586:
1396:
1385:
1177:
1157:
1152:
1126:
1070:
963:
953:
948:
651:
616:
601:
543:
357:
307:
291:
280:
241:
195:
83:, the route of drug administration is important because it affects
1182:
1111:
1050:
995:
990:
958:
798:
754:
631:
207:
173:
123:
1104:
1172:
1092:
1005:
825:
736:
626:
591:
578:
269:
164:
127:
39:
A medical professional injects medication into a gastric tube.
1060:
785:
687:
646:
525:
255:
229:
119:
236:
808:
489:
134:) or a tube in the belly leading directly to the stomach (
74:), which occurs from routes outside the GI tract, such as
924:
869:
301:
322:
to occur, the drug has to diffuse through the lipid
341:Factors influencing gastrointestinal absorption:
138:). Rectal administration usually involves rectal
1413:
475:
482:
468:
370:
109:
66:nutrition or drug administration (Greek
42:
34:
26:
414:"Enteral administration - pharmacology"
14:
1414:
463:
437:
839:Heated humidified high-flow therapy
24:
1103:
1041:
934:
314:, which are both absorbed through
302:Drug absorption from the intestine
237:Osmotic controlled release capsule
25:
1433:
47:Administering medication rectally
1281:
807:
568:
562:
431:
406:
13:
1:
607:Effervescent powder or tablet
399:
1391:Patient-controlled analgesia
696:Orally disintegrating tablet
440:Rang and Dale's Pharmacology
60:human gastrointestinal tract
7:
382:
10:
1438:
902:Relative analgesia machine
316:carrier-mediated transport
54:administration is food or
1346:
1318:
1290:
1279:
1243:
1210:
1091:
1029:
982:
918:
868:
824:
805:
784:
770:
735:
686:
664:
577:
560:
524:
510:
501:
442:. Elsevier. p. 104.
346:Gastrointestinal motility
147:
1422:Routes of administration
491:Routes of administration
389:Enteric (disambiguation)
126:), and rectal (from the
122:), gastric (through the
105:
1017:Extra-amniotic infusion
622:Molecular encapsulation
554:Osmotic delivery system
549:Time release technology
220:Time release technology
1320:Central nervous system
1108:
1046:
974:Mucoadhesive microdisc
939:
115:
62:. This contrasts with
48:
40:
32:
1163:Transfersome vesicles
1107:
1045:
1022:Intravesical infusion
938:
377:first pass metabolism
371:First pass metabolism
360:size and formulation.
156:Rectal administration
113:
46:
38:
30:
849:Metered-dose inhaler
834:Anesthetic vaporizer
438:Rang, H. P. (2007).
1274:Transdermal implant
1234:(into tissue/blood)
1011:Intrauterine device
892:Anaesthetic machine
887:Oxygen concentrator
150:Oral administration
95:. The term is from
56:drug administration
1386:Nanocell injection
1109:
1047:
940:
794:Dry-powder inhaler
116:
49:
41:
33:
1409:
1408:
1405:
1404:
1236:
1198:Transdermal spray
1193:Transdermal patch
1183:Medicated shampoo
914:
913:
910:
909:
897:Medical inhalants
844:Medical inhalants
772:Respiratory tract
766:
765:
660:
659:
299:
298:
16:(Redirected from
1429:
1285:
1241:
1240:
1232:
819:
815:
811:
782:
781:
711:Sublingual drops
684:
683:
572:
566:
522:
521:
508:
507:
484:
477:
470:
461:
460:
454:
453:
435:
429:
428:
426:
424:
410:
336:lipid solubility
328:epithelial cells
320:passive transfer
145:
144:
21:
1437:
1436:
1432:
1431:
1430:
1428:
1427:
1426:
1412:
1411:
1410:
1401:
1381:Intraperitoneal
1353:musculoskeletal
1351:
1342:
1314:
1310:Intra-articular
1286:
1277:
1237:
1231:
1230:
1206:
1087:
1025:
978:
923:
906:
864:
820:
817:
816:
813:
812:
803:
762:
731:
656:
573:
567:
558:
512:Digestive tract
497:
488:
458:
457:
450:
436:
432:
422:
420:
412:
411:
407:
402:
385:
373:
364:Physicochemical
304:
108:
85:drug metabolism
23:
22:
15:
12:
11:
5:
1435:
1425:
1424:
1407:
1406:
1403:
1402:
1400:
1399:
1394:
1388:
1383:
1378:
1373:
1368:
1363:
1357:
1355:
1344:
1343:
1341:
1340:
1335:
1330:
1324:
1322:
1316:
1315:
1313:
1312:
1307:
1302:
1300:Intracavernous
1296:
1294:
1288:
1287:
1280:
1278:
1276:
1271:
1270:
1269:
1259:
1254:
1252:
1238:
1229:
1228:
1223:
1218:
1212:
1211:
1208:
1207:
1205:
1200:
1195:
1190:
1185:
1180:
1175:
1170:
1165:
1160:
1155:
1150:
1145:
1139:
1134:
1129:
1124:
1119:
1114:
1102:
1100:
1089:
1088:
1086:
1085:
1083:Nutrient enema
1080:
1075:
1074:
1073:
1068:
1058:
1053:
1040:
1038:
1027:
1026:
1024:
1019:
1014:
1008:
1003:
998:
993:
988:
986:
980:
979:
977:
976:
971:
966:
961:
956:
951:
946:
933:
931:
916:
915:
912:
911:
908:
907:
905:
904:
899:
894:
889:
884:
874:
872:
866:
865:
863:
862:
857:
852:
846:
841:
836:
830:
828:
822:
821:
806:
804:
802:
801:
796:
790:
788:
779:
768:
767:
764:
763:
761:
760:
757:
752:
747:
741:
739:
733:
732:
730:
729:
724:
718:
713:
708:
703:
698:
692:
690:
681:
662:
661:
658:
657:
655:
654:
649:
644:
639:
634:
629:
624:
619:
614:
609:
604:
599:
594:
589:
583:
581:
575:
574:
561:
559:
557:
556:
551:
546:
541:
536:
530:
528:
519:
505:
499:
498:
487:
486:
479:
472:
464:
456:
455:
448:
430:
418:britannica.com
404:
403:
401:
398:
397:
396:
391:
384:
381:
372:
369:
368:
367:
361:
355:
349:
303:
300:
297:
296:
294:
289:
286:
285:
283:
278:
275:
274:
272:
267:
264:
263:
261:Nutrient enema
258:
253:
250:
249:
244:
239:
233:
232:
227:
222:
216:
215:
210:
205:
199:
198:
193:
188:
182:
181:
178:
169:
159:
158:
153:
107:
104:
89:drug clearance
70:, "besides" +
9:
6:
4:
3:
2:
1434:
1423:
1420:
1419:
1417:
1398:
1395:
1392:
1389:
1387:
1384:
1382:
1379:
1377:
1374:
1372:
1371:Intramuscular
1369:
1367:
1364:
1362:
1359:
1358:
1356:
1354:
1349:
1345:
1339:
1336:
1334:
1331:
1329:
1328:Intracerebral
1326:
1325:
1323:
1321:
1317:
1311:
1308:
1306:
1303:
1301:
1298:
1297:
1295:
1293:
1289:
1284:
1275:
1272:
1268:
1265:
1264:
1263:
1260:
1258:
1255:
1253:
1250:
1246:
1242:
1239:
1235:
1227:
1224:
1222:
1219:
1217:
1214:
1213:
1209:
1204:
1201:
1199:
1196:
1194:
1191:
1189:
1186:
1184:
1181:
1179:
1176:
1174:
1171:
1169:
1166:
1164:
1161:
1159:
1156:
1154:
1151:
1149:
1148:Iontophoresis
1146:
1143:
1140:
1138:
1135:
1133:
1130:
1128:
1125:
1123:
1120:
1118:
1117:Topical cream
1115:
1113:
1110:
1106:
1101:
1098:
1094:
1090:
1084:
1081:
1079:
1076:
1072:
1069:
1067:
1064:
1063:
1062:
1059:
1057:
1054:
1052:
1049:
1048:
1044:
1039:
1036:
1032:
1028:
1023:
1020:
1018:
1015:
1012:
1009:
1007:
1004:
1002:
999:
997:
994:
992:
989:
987:
985:
981:
975:
972:
970:
967:
965:
962:
960:
957:
955:
952:
950:
947:
945:
942:
941:
937:
932:
930:
926:
921:
917:
903:
900:
898:
895:
893:
890:
888:
885:
883:
882:Nasal cannula
879:
876:
875:
873:
871:
867:
861:
858:
856:
853:
850:
847:
845:
842:
840:
837:
835:
832:
831:
829:
827:
823:
810:
800:
797:
795:
792:
791:
789:
787:
783:
780:
777:
773:
769:
758:
756:
753:
751:
748:
746:
743:
742:
740:
738:
734:
728:
725:
722:
719:
717:
714:
712:
709:
707:
704:
702:
699:
697:
694:
693:
691:
689:
685:
682:
679:
675:
671:
667:
663:
653:
650:
648:
645:
643:
640:
638:
635:
633:
630:
628:
625:
623:
620:
618:
615:
613:
610:
608:
605:
603:
600:
598:
595:
593:
590:
588:
585:
584:
582:
580:
576:
571:
565:
555:
552:
550:
547:
545:
542:
540:
537:
535:
532:
531:
529:
527:
523:
520:
517:
513:
509:
506:
504:
500:
496:
492:
485:
480:
478:
473:
471:
466:
465:
462:
451:
449:0-443-06911-5
445:
441:
434:
419:
415:
409:
405:
395:
392:
390:
387:
386:
380:
378:
365:
362:
359:
356:
353:
350:
347:
344:
343:
342:
339:
337:
333:
329:
325:
324:cell membrane
321:
317:
313:
309:
295:
293:
290:
288:
287:
284:
282:
279:
277:
276:
273:
271:
268:
266:
265:
262:
259:
257:
254:
252:
251:
248:
245:
243:
240:
238:
235:
234:
231:
228:
226:
223:
221:
218:
217:
214:
211:
209:
206:
204:
201:
200:
197:
194:
192:
189:
187:
184:
183:
179:
177:
176:
175:
170:
168:
167:
166:
161:
160:
157:
154:
152:
151:
146:
143:
141:
140:suppositories
137:
133:
129:
125:
121:
112:
103:
102:'intestine'.
101:
98:
94:
90:
86:
82:
77:
73:
69:
65:
61:
57:
53:
45:
37:
29:
19:
1376:Intraosseous
1366:Intracardiac
1305:Intravitreal
1267:Injector pen
1262:Subcutaneous
1233:
1203:Jet injector
1188:Dermal patch
1034:
1001:Vaginal ring
969:Insufflation
721:Effervescent
515:
495:dosage forms
439:
433:
421:. Retrieved
417:
408:
394:Feeding tube
374:
340:
312:fluorouracil
305:
172:
171:
163:
162:
155:
148:
117:
99:
81:pharmacology
71:
67:
51:
50:
1361:Intravenous
1348:Circulatory
1333:Intrathecal
1257:Intradermal
1249:transdermal
1216:Parenterals
1122:Topical gel
1078:Murphy drip
1056:Suppository
944:Nasal spray
878:Oxygen mask
727:Chewing gum
666:Oral mucosa
354:blood flow.
247:Murphy drip
213:Suppository
91:, and thus
76:intravenous
1221:Injections
984:Urogenital
920:Ophthalmic
776:inhalation
750:Toothpaste
678:sublingual
642:Suspension
612:Herbal tea
400:References
352:Splanchnic
332:Ionization
225:Suspension
64:parenteral
1226:infusions
1158:Liposomes
954:Eye drops
949:Ear drops
860:Vaporizer
855:Nebulizer
745:Mouthwash
674:sublabial
597:Electuary
587:Decoction
1416:Category
1397:PIC line
1338:Epidural
1178:Lip balm
1153:Hydrogel
1144:solution
1127:Liniment
1112:Ointment
1071:Hydrogel
1066:Solution
1051:Ointment
991:Ointment
964:Hydrogel
959:Ointment
755:Ointment
716:Lozenges
706:Lollipop
652:Tincture
637:Solution
617:Hydrogel
602:Emulsion
544:Pastille
423:19 April
383:See also
366:factors.
358:Particle
308:levodopa
292:hydrogel
281:Tincture
242:Emulsion
196:Ointment
191:Solution
136:PEG tube
58:via the
1097:topical
1035:enteral
996:Pessary
826:Liquids
799:Smoking
737:Liquids
632:Softgel
579:Liquids
539:Capsule
516:enteral
326:of the
208:Softgel
174:Liquids
132:NG tube
124:stomach
100:enteros
72:enteros
52:Enteral
18:Enteral
1292:Organs
1173:Lotion
1093:Dermal
1031:Rectal
1006:Douche
786:Solids
723:tablet
688:Solids
670:buccal
627:Powder
592:Elixir
534:Tablet
526:Solids
446:
318:. For
270:Elixir
203:Tablet
165:Solids
128:rectum
93:dosage
1168:Cream
1132:Paste
1061:Enema
1013:(IUD)
929:nasal
851:(MDI)
759:Spray
647:Syrup
256:Syrup
230:Enema
120:mouth
106:Forms
97:Greek
1393:pump
1245:Skin
1142:DMSO
1137:Film
925:otic
880:and
701:Film
503:Oral
444:ISBN
425:2018
334:and
310:and
186:Pill
68:para
870:Gas
142:.)
1418::
927:,
676:,
672:,
493:,
416:.
338:.
180:-
87:,
1350:,
1251:)
1247:(
1099:)
1095:(
1037:)
1033:(
922:,
818:0
814:0
778:)
774:(
680:)
668:(
518:)
514:(
483:e
476:t
469:v
452:.
427:.
348:.
20:)
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.