1148:, some doctors observed that anecdotally some hospitalized patients in China may have had better outcomes on famotidine than other patients that were not taking famotidine. This led to hypotheses about use of famotidine in treatment of COVID-19. Famotidine was considered a possible treatment for COVID-19 due to its potential anti-inflammatory effects. It was thought that famotidine could modify lung inflammation caused by coronaviruses. However, studies have shown that famotidine is not effective in reducing mortality or improving recovery in COVID-19 patients. Famotidine primarily works by blocking the effects of histamine and has some potential mechanisms of action that may contribute to its anti-inflammatory properties, including the inhibition of the production of certain pro-inflammatory cytokines such as
660:
637:
58:
1104:(50%) due to low gastroretention time. Famotidine is less soluble at higher pH, and when used in combination with antacids gastroretention time is increased. This promotes local delivery of these drugs to receptors in the parietal cell membrane and increases bioavailibility. Researchers are developing tablet formulations that rely on other gastroretentive drug delivery systems such as floating tablets to further increase bioavailibility.
2261:
2900:
49:
4914:
954:
Famotidine has a delayed onset of action, beginning after 90 minutes. However, famotidine has a duration of effect of at least 540 minutes (9.0 h). At its peak effect, 210 minutes (3.5 h) after administration, famotidine reduces acid secretion by 7.3 mmol per 30 minutes.
2259:, Yasufumi Hirata, Isao Yanagisawa, Yoshio Ishii, Shinichi Tsukamoto, Noriki Ito, Yasuo Isomura and Masaaki Takeda, "Guanidinothiazole compounds, process for preparation and gastric inhibiting compositions containing them", issued 11 August 1981
1042:
enzyme system, and does not appear to interact with as many drugs as other medications in its class. Some exceptions include antiretrovirals such as atazanavir, chemotherapeutics such as doxorubicin, and antifungal medications such as itraconazole.
2169:
Hegazy SK, El-Haggar SM, Alhassanin SA, El-Berri EI (January 2021). "Comparative randomized trial evaluating the effect of proton pump inhibitor versus histamine 2 receptor antagonist as an adjuvant therapy in diffuse large B-cell lymphoma".
1172:. However, while famotidine may have some anti-inflammatory effects, there is currently insufficient evidence to support its use for treating inflammation associated with COVID-19. Therefore, it is not recommended for this purpose.
2484:
31:
1505:
Soga T, Matsuura M, Kodama Y, Fujita T, Sekimoto I, Nishimura K, et al. (August 1999). "Is a proton pump inhibitor necessary for the treatment of lower-grade reflux esophagitis?".
279:
1599:"Comparison of H2-receptor antagonist- and proton-pump inhibitor-based triple regimens for the eradication of Helicobacter pylori in Chinese patients with gastritis or peptic ulcer"
1097:
in a chewable tablet to quickly relieve the symptoms of excess stomach acid, is available. In the UK, this product was known as PepcidTwo until its discontinuation in April 2015.
2213:
Lim SG, Sawyerr AM, Hudson M, Sercombe J, Pounder RE (June 1993). "Short report: the absorption of fluconazole and itraconazole under conditions of low intragastric acidity".
1939:
Feldman M (May 1996). "Comparison of the effects of over-the-counter famotidine and calcium carbonate antacid on postprandial gastric acid. A randomized controlled trial".
1289:
1259:
4488:
2303:"Famotidine, a new, potent, long-acting histamine H2-receptor antagonist: comparison with cimetidine and ranitidine in the treatment of Zollinger-Ellison syndrome"
2012:
2931:
2844:
234:
2275:
735:
2466:
2122:"Effects of the H2-receptor antagonist famotidine on the pharmacokinetics of atazanavir-ritonavir with or without tenofovir in HIV-infected patients"
3611:
1767:"Double-blind randomized trials of single-tablet ibuprofen/high-dose famotidine vs. ibuprofen alone for reduction of gastric and duodenal ulcers"
4083:
4078:
4018:
3978:
3887:
3867:
3586:
3506:
3486:
1896:
Jahr JS, Burckart G, Smith SS, Shapiro J, Cook DR (July 1991). "Effects of famotidine on gastric pH and residual volume in pediatric surgery".
1722:
La Corte R, Caselli M, Castellino G, Bajocchi G, Trotta F (June 1999). "Prophylaxis and treatment of NSAID-induced gastroduodenal disorders".
1675:"Famotidine vs. omeprazole: a prospective randomized multicentre trial to determine efficacy in non-erosive gastro-oesophageal reflux disease"
4820:
4642:
4481:
4113:
4048:
3993:
3877:
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128:
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3401:
749:
4269:
4118:
4103:
4063:
4028:
3892:
3636:
3596:
3576:
3566:
3476:
2924:
1396:
1982:
4239:
3852:
4850:
4234:
4229:
4474:
4450:
1116:(OTC) in various countries. In the United States and Canada, 10 mg and 20 mg tablets, sometimes in combination with an
2413:
1281:
1251:
4455:
2917:
4868:
4835:
1456:
1426:
1330:
1220:
2874:
2368:
2342:
777:
InChI=1S/C8H15N7O2S3/c9-6(15-20(12,16)17)1-2-18-3-5-4-19-8(13-5)14-7(10)11/h4H,1-3H2,(H2,9,15)(H2,12,16,17)(H4,10,11,13,14)
2717:"Antihistamines improve cardiovascular manifestations and other symptoms of long-COVID attributed to mast cell activation"
3944:
2984:
1160:
inflammatory reflex to attenuate cytokine storm. Yet another hypothesis was that famotidine can reduce the activation of
935:
1816:"Effects of omeprazole, ranitidine, famotidine and placebo on gastric secretion in patients undergoing elective surgery"
4667:
2004:
794:
179:
2562:"No evidence of clinical efficacy of famotidine for the treatment of COVID-19: a systematic review and meta-analysis"
1390:
1363:
1063:
ring of cimetidine was replaced with a 2-guanidinothiazole ring. Famotidine proved to be nine times more potent than
769:
2816:
4944:
4885:
4825:
4502:
909:
828:
382:
264:
160:
2443:
2279:
899:
457:
4445:
1075:
903:
655:
508:
1180:
Small-scale studies have shown inconsistent and inconclusive evidence of efficacy in treatment-refractory
2904:
616:
846:
Common side effects include headache, intestinal upset, and dizziness. Serious side effects may include
4904:
3725:
832:
2256:
869:. In 2022, it was the 49th most commonly prescribed medication in the United States, with more than 13
577:
1052:
1007:
3755:
3226:
2085:
Lee KW, Kayser SR, Hongo RH, Tseng ZH, Scheinman MM (May 2004). "Famotidine and long QT syndrome".
2036:"Drugs to be avoided in patients with long QT syndrome: Focus on the anaesthesiological management"
632:
4873:
3016:
2614:"Famotidine: A potential mitigator of mast cell activation in post-COVID-19 cognitive impairment"
2405:
216:
118:
4830:
4573:
3646:
2768:"Clinical update on COVID-19 for the emergency and critical care clinician: Medical management"
2301:
Howard JM, Chremos AN, Collen MJ, McArthur KE, Cherner JA, Maton PN, et al. (April 1985).
1165:
598:
338:
4466:
1380:
4709:
4597:
4361:
4338:
4155:
4137:
3906:
3809:
2951:
1974:
1113:
557:
448:
305:
17:
4724:
1169:
942:
824:
517:
412:
348:
497:
8:
4959:
4949:
4939:
3156:
2969:
2664:
Yang H, George SJ, Thompson DA, Silverman HA, Tsaava T, Tynan A, et al. (May 2022).
2560:
Cheema HA, Shafiee A, Athar M, Shahid A, Awan RU, Afifi AM, et al. (February 2023).
1083:
923:
836:
403:
223:
2743:
2716:
2638:
2613:
865:
Famotidine was patented in 1979 and came into medical use in 1985. It is available as a
659:
636:
4954:
4729:
4558:
3221:
3151:
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1856:
1791:
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1747:
1704:
1628:
1574:
1549:
1530:
866:
292:
190:
2666:"Famotidine activates the vagus nerve inflammatory reflex to attenuate cytokine storm"
2506:
Malone RW, Tisdall P, Fremont-Smith P, Liu Y, Huang XP, White KM, et al. (2021).
2319:
2302:
4934:
4356:
3707:
2836:
2797:
2766:
Long B, Chavez S, Carius BM, Brady WJ, Liang SY, Koyfman A, et al. (June 2022).
2748:
2697:
2643:
2629:
2591:
2539:
2324:
2230:
2199:
2187:
2151:
2102:
2067:
1956:
1952:
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1878:
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1620:
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1522:
1487:
1386:
1359:
1145:
588:
152:
57:
2715:
Salvucci F, Codella R, Coppola A, Zacchei I, Grassi G, Anti ML, et al. (2023).
2242:
1925:
1751:
1708:
1673:
Fujiwara Y, Higuchi K, Nebiki H, Chono S, Uno H, Kitada K, et al. (June 2005).
1632:
1534:
4799:
3833:
3700:
3316:
3176:
3096:
2828:
2787:
2779:
2738:
2728:
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2633:
2625:
2581:
2573:
2529:
2519:
2474:
2314:
2222:
2179:
2141:
2133:
2094:
2057:
2047:
1948:
1905:
1868:
1857:"Acid aspiration prophylaxis in morbidly obese patients: famotidine vs. ranitidine"
1827:
1786:
1778:
1731:
1686:
1610:
1569:
1561:
1550:"Omeprazole enhances efficacy of triple therapy in eradicating Helicobacter pylori"
1514:
1078:
were released in 1999. Generic preparations became available in 2001, e.g. Fluxid (
672:
320:
247:
75:
2098:
1448:
1418:
1322:
1212:
138:
4918:
4612:
3236:
3196:
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3056:
2866:
2393:
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2346:
1101:
1090:
1039:
987:
983:
893:
437:
328:
4506:
2909:
2120:
Wang X, Boffito M, Zhang J, Chung E, Zhu L, Wu Y, et al. (September 2011).
1059:
and is marketed by a joint venture between Merck and
Johnson & Johnson. The
986:, particularly when used with other QT-elongating drugs, or in people with poor
4879:
4284:
3813:
3703:
3526:
3466:
3381:
3216:
3161:
3131:
3091:
3081:
3076:
2783:
2682:
2577:
2183:
1615:
1598:
1128:
1079:
1056:
1003:
889:
2733:
2524:
2369:"Formulation and Evaluation of Gastroretentive Floating Tablets of Famotidine"
1548:
Borody TJ, Andrews P, Fracchia G, Brandl S, Shortis NP, Bae H (October 1995).
4928:
4734:
4652:
4568:
4515:
3799:
3795:
3759:
3719:
3662:
3658:
3521:
3471:
3361:
3346:
3271:
3266:
3071:
1181:
1153:
1011:
859:
812:
648:
2479:
2467:"New York clinical trial quietly tests heartburn remedy against coronavirus"
1022:
on the parietal cells, ultimately reducing acid secretion into the stomach.
898:
Treatment for pathologic gastrointestinal hypersecretory conditions such as
4779:
4719:
4637:
4627:
4617:
4607:
4498:
4415:
4319:
4259:
4180:
4053:
3837:
3829:
3821:
3817:
3803:
3767:
3763:
3749:
3678:
3650:
3516:
3501:
3386:
3376:
3371:
3366:
3341:
3336:
3306:
3286:
3276:
3241:
3191:
3121:
3041:
2840:
2801:
2752:
2701:
2647:
2595:
2543:
2191:
2155:
2106:
2071:
1832:
1815:
1800:
1743:
1700:
1659:
1624:
1526:
1491:
972:
820:
242:
40:
2328:
2234:
2137:
1960:
1917:
1882:
1841:
1583:
1518:
4784:
4759:
4754:
4749:
4714:
4657:
4647:
4582:
4543:
4400:
4371:
4304:
4299:
4294:
4279:
4244:
4185:
4160:
4123:
4033:
3954:
3949:
3841:
3791:
3771:
3745:
3737:
3690:
3686:
3670:
3626:
3591:
3571:
3551:
3546:
3431:
3396:
3356:
3321:
3311:
3296:
3261:
3251:
3231:
3211:
3206:
3201:
3166:
3116:
3111:
3101:
3046:
3021:
2989:
2974:
2832:
2052:
1782:
1765:
Laine L, Kivitz AJ, Bello AE, Grahn AY, Schiff MH, Taha AS (March 2012).
1565:
1157:
916:
840:
227:
146:
477:
4804:
4774:
4769:
4764:
4693:
4683:
4678:
4632:
4622:
4553:
4548:
4538:
4528:
4420:
4309:
4274:
4254:
4249:
4193:
4098:
4093:
4088:
4068:
4058:
4038:
4023:
4003:
3988:
3983:
3783:
3711:
3682:
3674:
3601:
3536:
3496:
3491:
3456:
3451:
3411:
3406:
3331:
3256:
3181:
3146:
3136:
3106:
3086:
3066:
3026:
1068:
1064:
1031:
928:
711:
488:
32:
United
Nations Economic Commission for Latin America and the Caribbean
4794:
4789:
4744:
4739:
4587:
4405:
4366:
4314:
4264:
4165:
4043:
3939:
3924:
3787:
3775:
3741:
3729:
3715:
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3654:
3616:
3606:
3556:
3511:
3461:
3436:
3351:
3326:
3301:
3291:
3281:
3246:
3186:
3126:
3061:
3051:
3031:
2979:
1161:
1149:
1124:
1060:
1019:
968:
882:
855:
847:
423:
361:
132:
2435:
963:
The most common side effects associated with famotidine use include
4425:
4384:
4324:
4219:
4214:
4198:
3934:
3929:
3825:
3733:
3694:
3481:
3036:
976:
964:
851:
537:
468:
174:
941:
Given to surgery patients before operations to reduce the risk of
734:
604:
4224:
4175:
3962:
3779:
2997:
2168:
1814:
Escolano F, Castaño J, López R, Bisbe E, Alcón A (October 1992).
1721:
1117:
1094:
1120:, are available OTC. Larger doses still require a prescription.
30:"Cepal" redirects here. For the international organization, see
4496:
4379:
4170:
2899:
568:
366:
1855:
Vila P, Vallès J, Canet J, Melero A, Vidal F (November 1991).
1449:"Famotidine Drug Usage Statistics, United States, 2013 - 2022"
102:
2714:
2508:"COVID-19: Famotidine, Histamine, Mast Cells, and Mechanisms"
2505:
858:
appears safe but has not been well studied, while use during
725:
548:
48:
1156:. Another hypothesis was that famotidine might activate the
621:
2663:
2300:
1547:
1358:(76 ed.). Pharmaceutical Press. 2018. pp. 74–75.
528:
81:
1672:
1645:
90:
2817:"Famotidine Augmentation in Schizophrenia: Hope or Hype?"
2335:
1813:
1646:
Kirika NV, Bodrug NI, Butorov IV, Butorov SI (2004). "".
96:
2559:
2212:
1975:"Common Side Effects of Pepcid (Famotidine) Drug Center"
1895:
1504:
2398:
2034:
Fazio G, Vernuccio F, Grutta G, Re GL (26 April 2013).
1274:
1192:
Famotidine is given to dogs and cats with acid reflux.
1010:
to secrete acid into the stomach lumen. Famotidine, an
2268:
2033:
1997:
1246:
1244:
1242:
1240:
1238:
4902:
2765:
2119:
1854:
1764:
105:
78:
2612:
Kow CS, Ramachandram DS, Hasan SS (September 2023).
2611:
99:
93:
2084:
1480:
Nihon Rinsho. Japanese
Journal of Clinical Medicine
1235:
1038:antagonist, famotidine has a minimal effect on the
456:
87:
84:
2361:
1967:
1089:In the United States and Canada, a product called
2939:
2249:
1329:. American Society of Health-System Pharmacists.
1213:"Famotidine Pregnancy and Breastfeeding Warnings"
1112:Certain preparations of famotidine are available
4926:
2859:
2428:
436:
2659:
2657:
2607:
2605:
2555:
2553:
2387:
1378:
1123:Formulations of famotidine in combination with
411:
4821:Bismuth subcitrate/metronidazole/tetracycline
4482:
2925:
1603:The Journal of International Medical Research
2759:
2708:
2654:
2602:
2550:
2499:
2458:
2162:
2113:
2078:
2027:
1758:
1715:
1666:
1639:
1590:
1498:
1282:"Zantac 360- famotidine tablet, film coated"
178:
2294:
2206:
1932:
1889:
1848:
1807:
1596:
1541:
1471:
1372:
4489:
4475:
2932:
2918:
2772:The American Journal of Emergency Medicine
2215:Alimentary Pharmacology & Therapeutics
1679:Alimentary Pharmacology & Therapeutics
1317:
1315:
1313:
1311:
1309:
1307:
1207:
1205:
1074:It was first marketed in 1981. Pepcid RPD
658:
635:
496:
2791:
2742:
2732:
2691:
2681:
2637:
2585:
2533:
2523:
2478:
2318:
2278:. Skyscape Mediwire. 2002. Archived from
2145:
2061:
2051:
1872:
1831:
1790:
1690:
1614:
1573:
516:
1771:The American Journal of Gastroenterology
1477:
1356:British national formulary : BNF 76
1323:"Famotidine Monograph for Professionals"
1067:, and thirty-two times more potent than
1055:Co. It was licensed in the mid-1980s by
2814:
2464:
1938:
1350:
1348:
1304:
1202:
631:
476:
151:
14:
4927:
1597:Hu FL, Jia JC, Li YL, Yang GB (2003).
1385:. John Wiley & Sons. p. 444.
1107:
993:
757:NS(=O)(=O)/N=C(\N)CCSCc1csc(n1)N=C(N)N
649:
286:
4836:Vonoprazan/amoxicillin/clarithromycin
4470:
2913:
2446:from the original on 26 November 2020
2371:. Farmavita.Net. 2008. Archived from
1223:from the original on 16 December 2023
597:
576:
556:
390:3--1,3-thiazol-4-yl}methyl)sulfanyl]-
299:
169:
137:
2847:from the original on 11 January 2024
1345:
1093:, which combines famotidine with an
885:, acid indigestion, and sour stomach
843:. It begins working within an hour.
603:
246:
27:Medication that reduces stomach acid
2416:from the original on 4 October 2022
1898:Acta Anaesthesiologica Scandinavica
1429:from the original on 30 August 2024
949:
536:
427:
24:
3197:Etybenzatropine (ethylbenztropine)
2821:The Journal of Clinical Psychiatry
2487:from the original on 29 April 2020
2227:10.1111/j.1365-2036.1993.tb00103.x
2087:The American Journal of Cardiology
1910:10.1111/j.1399-6576.1991.tb03328.x
1874:10.1111/j.1365-2044.1991.tb09860.x
1459:from the original on 17 April 2020
1262:from the original on 31 March 2024
1187:
25:
4971:
2893:
2015:from the original on 6 March 2019
1985:from the original on 6 March 2019
1399:from the original on 29 July 2020
1333:from the original on 17 June 2019
273:
201:
4912:
4826:Omeprazole/amoxicillin/rifabutin
2898:
2877:from the original on 19 May 2015
2630:10.1016/j.jpsychores.2023.111425
1953:10.1001/jama.1996.03530420056036
1736:10.2165/00002018-199920060-00006
1692:10.1111/j.1365-2036.2005.02468.x
1292:from the original on 6 July 2022
921:Part of a multidrug regimen for
823:production. It is used to treat
689:
683:
282:(Pharmacist only) / S4
74:
56:
47:
4451:Monoamine metabolism modulators
1478:Kanayama S (January 1999). "".
1379:Fischer J, Ganellin CR (2006).
1025:
958:
931:may be somewhat more effective.
910:gastroesophageal reflux disease
876:
829:gastroesophageal reflux disease
782:Key:XUFQPHANEAPEMJ-UHFFFAOYSA-N
1820:British Journal of Anaesthesia
1441:
1411:
1164:and the subsequent release of
701:
695:
677:
13:
1:
4456:Monoamine reuptake inhibitors
4446:Receptor/signaling modulators
2320:10.1016/s0016-5085(85)80024-x
2099:10.1016/j.amjcard.2004.02.025
1382:Analogue-based Drug Discovery
1195:
1131:under the trade name Duexis.
1076:orally disintegrating tablets
982:Famotidine may contribute to
1051:Famotidine was developed by
807:, sold under the brand name
7:
4079:Quisultazine (quisultidine)
3726:Tetracyclic antidepressants
2343:"PepcidTwo Chewable Tablet"
2040:World Journal of Cardiology
1507:Journal of Gastroenterology
1139:
1134:
904:multiple endocrine adenomas
10:
4976:
3042:Benzatropine (benztropine)
2784:10.1016/j.ajem.2022.03.036
2683:10.1186/s10020-022-00483-8
2578:10.1016/j.jinf.2022.11.022
2184:10.1007/s12032-020-01452-z
2126:AIDS Patient Care and STDs
1616:10.1177/147323000303100601
1046:
900:Zollinger–Ellison syndrome
833:Zollinger-Ellison syndrome
819:medication that decreases
667:Chemical and physical data
123:Pepcid, Zantac 360, others
29:
4863:
4844:
4813:
4702:
4666:
4596:
4567:
4514:
4438:
4393:
4349:
4337:
4207:
4148:
4136:
3971:
3917:
3905:
3756:Tricyclic antidepressants
3612:Sequifenadine (bicarphen)
3006:
2962:
2950:
2734:10.3389/fcvm.2023.1202696
2525:10.3389/fphar.2021.633680
2512:Frontiers in Pharmacology
2255:
2005:"Drugs & Medications"
1053:Yamanouchi Pharmaceutical
790:
765:
745:
723:
710:
671:
666:
647:
615:
587:
567:
547:
527:
507:
487:
467:
447:
422:
402:
394:-sulfamoylpropanimidamide
378:
373:
360:
347:
337:
327:
319:
263:
258:
233:
215:
189:
159:
145:
127:
117:
69:
64:
55:
46:
3394:Second/third-generation:
3227:Hydroxyethylpromethazine
2465:Borrell B (April 2020).
1175:
1168:, therefore acting as a
4945:H2 receptor antagonists
4544:Lavoltidine (loxtidine)
4034:Lavoltidine (loxtidine)
3647:Atypical antipsychotics
3592:Quifenadine (phencarol)
3257:Mepyramine (pyrilamine)
3017:4-Methyldiphenhydramine
2480:10.1126/science.abc4739
1648:Terapevticheskii Arkhiv
1018:, blocks the action of
938:-induced peptic ulcers.
873:million prescriptions.
4831:Vonoprazan/amoxicillin
4668:Potassium-competitive
4598:Proton-pump inhibitors
3810:Typical antipsychotics
1166:inflammatory mediators
943:aspiration pneumonitis
927:eradication, although
4854:eradication protocols
4710:Aceglutamide aluminum
3776:dosulepin (dothiepin)
2907:at Wikimedia Commons
2257:US patent 4283408
2138:10.1089/apc.2011.0113
1519:10.1007/s005350050292
1419:"The Top 300 of 2022"
1002:receptors located on
841:injection into a vein
4725:Arbaclofen placarbil
2833:10.4088/JCP.13f08707
2721:Front Cardiovasc Med
2053:10.4330/wjc.v5.i4.87
1833:10.1093/bja/69.4.404
1783:10.1038/ajg.2011.443
1566:10.1136/gut.37.4.477
1170:mast cell stabilizer
1144:At the start of the
1100:Famotidine has poor
862:is not recommended.
825:peptic ulcer disease
4852:Helicobacter pylori
3157:Dexchlorpheniramine
2970:2-Pyridylethylamine
2282:on 23 February 2009
1252:"Famotidine tablet"
1108:Society and culture
1084:Gedeon Richter Ltd.
994:Mechanism of action
924:Helicobacter pylori
817:receptor antagonist
811:among others, is a
369:(25–30% unchanged )
43:
4890:Never to phase III
4730:Bismuth subcitrate
3222:Homochlorcyclizine
3152:Dexbrompheniramine
2941:Histamine receptor
2815:Andrade C (2013).
867:generic medication
293:General sales list
39:
4900:
4899:
4464:
4463:
4434:
4433:
4362:α-Methylhistamine
4357:4-Methylhistamine
4333:
4332:
4156:α-Methylhistamine
4132:
4131:
3901:
3900:
3850:Unknown/unsorted:
3708:hydroxynefazodone
3014:First-generation:
2903:Media related to
2093:(10): 1325–1327.
1947:(18): 1428–1431.
1685:(Suppl 2): 10–8.
1146:COVID-19 pandemic
1127:were marketed by
802:
801:
736:Interactive image
617:CompTox Dashboard
333:40–45% (by mouth)
303:
290:
277:
205:
172:
16:(Redirected from
4967:
4917:
4916:
4915:
4908:
4800:Zinc L-carnosine
4491:
4484:
4477:
4468:
4467:
4374:
4347:
4346:
4188:
4146:
4145:
3957:
3915:
3914:
3834:prochlorperazine
3701:Phenylpiperazine
3317:Phenyltoloxamine
3177:Diphenylpyraline
3097:Chlorphenoxamine
2992:
2960:
2959:
2934:
2927:
2920:
2911:
2910:
2902:
2887:
2886:
2884:
2882:
2863:
2857:
2856:
2854:
2852:
2827:(9): e855–e858.
2812:
2806:
2805:
2795:
2763:
2757:
2756:
2746:
2736:
2712:
2706:
2705:
2695:
2685:
2661:
2652:
2651:
2641:
2609:
2600:
2599:
2589:
2557:
2548:
2547:
2537:
2527:
2503:
2497:
2496:
2494:
2492:
2482:
2462:
2456:
2455:
2453:
2451:
2432:
2426:
2425:
2423:
2421:
2402:
2396:
2391:
2385:
2384:
2382:
2380:
2375:on 29 March 2016
2365:
2359:
2358:
2356:
2354:
2345:. Archived from
2339:
2333:
2332:
2322:
2307:Gastroenterology
2298:
2292:
2291:
2289:
2287:
2272:
2266:
2265:
2264:
2260:
2253:
2247:
2246:
2210:
2204:
2203:
2172:Medical Oncology
2166:
2160:
2159:
2149:
2117:
2111:
2110:
2082:
2076:
2075:
2065:
2055:
2031:
2025:
2024:
2022:
2020:
2001:
1995:
1994:
1992:
1990:
1971:
1965:
1964:
1936:
1930:
1929:
1893:
1887:
1886:
1876:
1852:
1846:
1845:
1835:
1811:
1805:
1804:
1794:
1762:
1756:
1755:
1719:
1713:
1712:
1694:
1670:
1664:
1663:
1643:
1637:
1636:
1618:
1594:
1588:
1587:
1577:
1545:
1539:
1538:
1502:
1496:
1495:
1475:
1469:
1468:
1466:
1464:
1445:
1439:
1438:
1436:
1434:
1415:
1409:
1408:
1406:
1404:
1376:
1370:
1369:
1352:
1343:
1342:
1340:
1338:
1319:
1302:
1301:
1299:
1297:
1278:
1272:
1271:
1269:
1267:
1248:
1233:
1232:
1230:
1228:
1209:
1114:over the counter
950:Pharmacokinetics
872:
798:
797:
738:
718:
703:
697:
691:
685:
679:
662:
651:
640:
639:
625:
623:
607:
601:
580:
560:
540:
520:
500:
480:
460:
440:
430:
429:
415:
352:
311:
301:
298:
288:
285:
275:
272:
250:
203:
200:
182:
171:
168:
155:
141:
112:
111:
108:
107:
104:
101:
98:
95:
92:
89:
86:
83:
80:
60:
51:
44:
42:
38:
21:
4975:
4974:
4970:
4969:
4968:
4966:
4965:
4964:
4925:
4924:
4923:
4913:
4911:
4903:
4901:
4896:
4895:
4880:Clinical trials
4859:
4840:
4809:
4698:
4669:
4662:
4613:Dexlansoprazole
4600:
4592:
4572:
4563:
4519:
4510:
4495:
4465:
4460:
4430:
4389:
4372:
4342:
4329:
4203:
4186:
4141:
4128:
3967:
3955:
3910:
3897:
3704:antidepressants
3237:Isopromethazine
3172:Diphenhydramine
3057:Brompheniramine
3002:
2990:
2955:
2946:
2938:
2896:
2891:
2890:
2880:
2878:
2865:
2864:
2860:
2850:
2848:
2813:
2809:
2764:
2760:
2713:
2709:
2662:
2655:
2618:J Psychosom Res
2610:
2603:
2558:
2551:
2504:
2500:
2490:
2488:
2463:
2459:
2449:
2447:
2434:
2433:
2429:
2419:
2417:
2404:
2403:
2399:
2394:Pepcid Complete
2392:
2388:
2378:
2376:
2367:
2366:
2362:
2352:
2350:
2349:on 18 July 2016
2341:
2340:
2336:
2299:
2295:
2285:
2283:
2276:"Sankyo Pharma"
2274:
2273:
2269:
2262:
2254:
2250:
2211:
2207:
2167:
2163:
2118:
2114:
2083:
2079:
2032:
2028:
2018:
2016:
2003:
2002:
1998:
1988:
1986:
1973:
1972:
1968:
1937:
1933:
1894:
1890:
1853:
1849:
1812:
1808:
1763:
1759:
1720:
1716:
1671:
1667:
1644:
1640:
1595:
1591:
1546:
1542:
1503:
1499:
1476:
1472:
1462:
1460:
1447:
1446:
1442:
1432:
1430:
1417:
1416:
1412:
1402:
1400:
1393:
1377:
1373:
1366:
1354:
1353:
1346:
1336:
1334:
1321:
1320:
1305:
1295:
1293:
1288:. 17 May 2022.
1280:
1279:
1275:
1265:
1263:
1250:
1249:
1236:
1226:
1224:
1211:
1210:
1203:
1198:
1190:
1188:Veterinary uses
1178:
1142:
1137:
1110:
1102:bioavailibility
1091:Pepcid Complete
1082:) or Quamatel (
1057:Merck & Co.
1049:
1040:cytochrome P450
1037:
1028:
1015:
1001:
998:Activation of H
996:
988:kidney function
984:QT prolongation
961:
952:
894:duodenal ulcers
879:
870:
816:
793:
791:
786:
783:
778:
773:
772:
761:
758:
753:
752:
741:
716:
706:
700:
694:
688:
682:
643:
619:
611:
583:
563:
543:
523:
503:
483:
463:
443:
426:
418:
398:
395:
386:
385:
350:
339:Protein binding
329:Bioavailability
321:Pharmacokinetic
315:
309:
254:
218:
211:
192:
185:
77:
73:
35:
28:
23:
22:
15:
12:
11:
5:
4973:
4963:
4962:
4957:
4952:
4947:
4942:
4937:
4922:
4921:
4898:
4897:
4894:
4893:
4892:
4891:
4888:
4877:
4871:
4865:
4864:
4861:
4860:
4858:
4857:
4845:
4842:
4841:
4839:
4838:
4833:
4828:
4823:
4817:
4815:
4811:
4810:
4808:
4807:
4802:
4797:
4792:
4787:
4782:
4777:
4772:
4767:
4762:
4757:
4752:
4747:
4742:
4737:
4732:
4727:
4722:
4717:
4712:
4706:
4704:
4700:
4699:
4697:
4696:
4691:
4686:
4681:
4675:
4673:
4664:
4663:
4661:
4660:
4655:
4650:
4645:
4640:
4635:
4630:
4625:
4620:
4615:
4610:
4604:
4602:
4594:
4593:
4591:
4590:
4585:
4579:
4577:
4569:Prostaglandins
4565:
4564:
4562:
4561:
4556:
4551:
4546:
4541:
4536:
4531:
4525:
4523:
4517:
4512:
4511:
4494:
4493:
4486:
4479:
4471:
4462:
4461:
4459:
4458:
4453:
4448:
4443:
4439:
4436:
4435:
4432:
4431:
4429:
4428:
4423:
4418:
4413:
4408:
4403:
4397:
4395:
4391:
4390:
4388:
4387:
4382:
4377:
4369:
4364:
4359:
4353:
4351:
4344:
4340:
4335:
4334:
4331:
4330:
4328:
4327:
4322:
4317:
4312:
4307:
4302:
4297:
4292:
4287:
4285:Iodophenpropit
4282:
4277:
4272:
4267:
4262:
4257:
4252:
4247:
4242:
4237:
4232:
4227:
4222:
4217:
4211:
4209:
4205:
4204:
4202:
4201:
4196:
4191:
4183:
4178:
4173:
4168:
4163:
4158:
4152:
4150:
4143:
4139:
4134:
4133:
4130:
4129:
4127:
4126:
4121:
4116:
4111:
4106:
4101:
4096:
4091:
4086:
4081:
4076:
4071:
4066:
4061:
4056:
4051:
4046:
4041:
4036:
4031:
4026:
4021:
4016:
4011:
4006:
4001:
3996:
3991:
3986:
3981:
3975:
3973:
3969:
3968:
3966:
3965:
3960:
3952:
3947:
3942:
3937:
3932:
3927:
3921:
3919:
3912:
3908:
3903:
3902:
3899:
3898:
3896:
3895:
3890:
3885:
3880:
3875:
3870:
3865:
3860:
3855:
3846:
3845:
3814:chlorpromazine
3807:
3753:
3723:
3698:
3640:
3639:
3634:
3629:
3624:
3619:
3614:
3609:
3604:
3599:
3594:
3589:
3584:
3579:
3574:
3569:
3564:
3559:
3554:
3549:
3544:
3539:
3534:
3529:
3527:Levocetirizine
3524:
3519:
3514:
3509:
3504:
3499:
3494:
3489:
3484:
3479:
3474:
3469:
3467:Clobenztropine
3464:
3459:
3454:
3449:
3444:
3439:
3434:
3429:
3424:
3419:
3414:
3409:
3404:
3399:
3390:
3389:
3384:
3382:Tripelennamine
3379:
3374:
3369:
3364:
3359:
3354:
3349:
3344:
3339:
3334:
3329:
3324:
3319:
3314:
3309:
3304:
3299:
3294:
3289:
3284:
3279:
3274:
3269:
3264:
3259:
3254:
3249:
3244:
3239:
3234:
3229:
3224:
3219:
3217:Histapyrrodine
3214:
3209:
3204:
3199:
3194:
3189:
3184:
3179:
3174:
3169:
3164:
3162:Dimenhydrinate
3159:
3154:
3149:
3144:
3139:
3134:
3132:Cyproheptadine
3129:
3124:
3119:
3114:
3109:
3104:
3099:
3094:
3092:Chlorphenamine
3089:
3084:
3082:Chloropyramine
3079:
3077:Chlorcyclizine
3074:
3069:
3064:
3059:
3054:
3049:
3044:
3039:
3034:
3029:
3024:
3019:
3010:
3008:
3004:
3003:
3001:
3000:
2995:
2987:
2982:
2977:
2972:
2966:
2964:
2957:
2953:
2948:
2947:
2937:
2936:
2929:
2922:
2914:
2895:
2894:External links
2892:
2889:
2888:
2858:
2807:
2758:
2707:
2653:
2601:
2572:(2): 154–225.
2549:
2498:
2457:
2427:
2397:
2386:
2360:
2334:
2313:(4): 1026–33.
2293:
2267:
2248:
2221:(3): 317–321.
2205:
2161:
2132:(9): 509–515.
2112:
2077:
2026:
1996:
1966:
1931:
1888:
1847:
1806:
1757:
1714:
1665:
1638:
1589:
1540:
1497:
1470:
1440:
1410:
1391:
1371:
1364:
1344:
1303:
1273:
1234:
1200:
1199:
1197:
1194:
1189:
1186:
1177:
1174:
1141:
1138:
1136:
1133:
1129:Horizon Pharma
1109:
1106:
1048:
1045:
1035:
1027:
1024:
1013:
1004:parietal cells
999:
995:
992:
960:
957:
951:
948:
947:
946:
939:
934:Prevention of
932:
919:
915:Treatment for
913:
908:Treatment for
906:
896:
888:Treatment for
886:
878:
875:
835:. It is taken
814:
800:
799:
788:
787:
785:
784:
781:
779:
776:
768:
767:
766:
763:
762:
760:
759:
756:
748:
747:
746:
743:
742:
740:
739:
731:
729:
721:
720:
714:
708:
707:
704:
698:
692:
686:
680:
675:
669:
668:
664:
663:
653:
645:
644:
642:
641:
628:
626:
613:
612:
610:
609:
593:
591:
585:
584:
582:
581:
573:
571:
565:
564:
562:
561:
553:
551:
545:
544:
542:
541:
533:
531:
525:
524:
522:
521:
513:
511:
505:
504:
502:
501:
493:
491:
485:
484:
482:
481:
473:
471:
465:
464:
462:
461:
453:
451:
445:
444:
442:
441:
433:
431:
420:
419:
417:
416:
408:
406:
400:
399:
397:
396:
389:
381:
380:
379:
376:
375:
371:
370:
364:
358:
357:
354:
345:
344:
341:
335:
334:
331:
325:
324:
317:
316:
314:
313:
296:
283:
269:
267:
261:
260:
256:
255:
253:
252:
239:
237:
231:
230:
221:
219:administration
213:
212:
210:
209:
207:
197:
195:
187:
186:
184:
183:
165:
163:
157:
156:
149:
143:
142:
135:
125:
124:
121:
115:
114:
71:
67:
66:
62:
61:
53:
52:
26:
9:
6:
4:
3:
2:
4972:
4961:
4958:
4956:
4953:
4951:
4948:
4946:
4943:
4941:
4938:
4936:
4933:
4932:
4930:
4920:
4910:
4909:
4906:
4889:
4887:
4884:
4883:
4881:
4878:
4875:
4872:
4870:
4867:
4866:
4862:
4856:
4855:
4853:
4847:
4846:
4843:
4837:
4834:
4832:
4829:
4827:
4824:
4822:
4819:
4818:
4816:
4812:
4806:
4803:
4801:
4798:
4796:
4793:
4791:
4788:
4786:
4783:
4781:
4778:
4776:
4773:
4771:
4768:
4766:
4763:
4761:
4758:
4756:
4753:
4751:
4748:
4746:
4743:
4741:
4738:
4736:
4735:Carbenoxolone
4733:
4731:
4728:
4726:
4723:
4721:
4718:
4716:
4713:
4711:
4708:
4707:
4705:
4701:
4695:
4692:
4690:
4687:
4685:
4682:
4680:
4677:
4676:
4674:
4671:
4670:acid blockers
4665:
4659:
4656:
4654:
4653:Tenatoprazole
4651:
4649:
4646:
4644:
4641:
4639:
4636:
4634:
4631:
4629:
4626:
4624:
4621:
4619:
4616:
4614:
4611:
4609:
4606:
4605:
4603:
4599:
4595:
4589:
4586:
4584:
4581:
4580:
4578:
4575:
4570:
4566:
4560:
4557:
4555:
4552:
4550:
4547:
4545:
4542:
4540:
4537:
4535:
4532:
4530:
4527:
4526:
4524:
4521:
4513:
4508:
4504:
4500:
4492:
4487:
4485:
4480:
4478:
4473:
4472:
4469:
4457:
4454:
4452:
4449:
4447:
4444:
4441:
4440:
4437:
4427:
4424:
4422:
4419:
4417:
4414:
4412:
4409:
4407:
4404:
4402:
4399:
4398:
4396:
4392:
4386:
4383:
4381:
4378:
4376:
4370:
4368:
4365:
4363:
4360:
4358:
4355:
4354:
4352:
4348:
4345:
4343:
4336:
4326:
4323:
4321:
4318:
4316:
4313:
4311:
4308:
4306:
4303:
4301:
4298:
4296:
4293:
4291:
4288:
4286:
4283:
4281:
4278:
4276:
4273:
4271:
4268:
4266:
4263:
4261:
4258:
4256:
4253:
4251:
4248:
4246:
4243:
4241:
4238:
4236:
4233:
4231:
4228:
4226:
4223:
4221:
4218:
4216:
4213:
4212:
4210:
4206:
4200:
4197:
4195:
4192:
4190:
4184:
4182:
4179:
4177:
4174:
4172:
4169:
4167:
4164:
4162:
4159:
4157:
4154:
4153:
4151:
4147:
4144:
4142:
4135:
4125:
4122:
4120:
4117:
4115:
4112:
4110:
4107:
4105:
4102:
4100:
4097:
4095:
4092:
4090:
4087:
4085:
4082:
4080:
4077:
4075:
4072:
4070:
4067:
4065:
4062:
4060:
4057:
4055:
4052:
4050:
4047:
4045:
4042:
4040:
4037:
4035:
4032:
4030:
4027:
4025:
4022:
4020:
4017:
4015:
4012:
4010:
4007:
4005:
4002:
4000:
3997:
3995:
3992:
3990:
3987:
3985:
3982:
3980:
3977:
3976:
3974:
3970:
3964:
3961:
3959:
3953:
3951:
3948:
3946:
3943:
3941:
3938:
3936:
3933:
3931:
3928:
3926:
3923:
3922:
3920:
3916:
3913:
3911:
3904:
3894:
3891:
3889:
3886:
3884:
3881:
3879:
3876:
3874:
3871:
3869:
3866:
3864:
3861:
3859:
3856:
3854:
3851:
3848:
3847:
3843:
3839:
3835:
3831:
3827:
3823:
3819:
3815:
3811:
3808:
3805:
3801:
3800:protriptyline
3797:
3796:nortriptyline
3793:
3789:
3785:
3781:
3777:
3773:
3769:
3765:
3761:
3760:amitriptyline
3757:
3754:
3751:
3747:
3743:
3739:
3735:
3731:
3727:
3724:
3721:
3720:triazoledione
3717:
3713:
3709:
3705:
3702:
3699:
3696:
3692:
3688:
3684:
3680:
3676:
3672:
3668:
3664:
3663:brilaroxazine
3660:
3659:brexpiprazole
3656:
3652:
3648:
3645:
3642:
3641:
3638:
3635:
3633:
3630:
3628:
3625:
3623:
3620:
3618:
3615:
3613:
3610:
3608:
3605:
3603:
3600:
3598:
3595:
3593:
3590:
3588:
3585:
3583:
3580:
3578:
3575:
3573:
3570:
3568:
3565:
3563:
3560:
3558:
3555:
3553:
3550:
3548:
3545:
3543:
3540:
3538:
3535:
3533:
3530:
3528:
3525:
3523:
3522:Levocabastine
3520:
3518:
3515:
3513:
3510:
3508:
3505:
3503:
3500:
3498:
3495:
3493:
3490:
3488:
3485:
3483:
3480:
3478:
3475:
3473:
3472:Desloratadine
3470:
3468:
3465:
3463:
3460:
3458:
3455:
3453:
3450:
3448:
3445:
3443:
3440:
3438:
3435:
3433:
3430:
3428:
3425:
3423:
3420:
3418:
3415:
3413:
3410:
3408:
3405:
3403:
3400:
3398:
3395:
3392:
3391:
3388:
3385:
3383:
3380:
3378:
3375:
3373:
3370:
3368:
3365:
3363:
3362:Thenyldiamine
3360:
3358:
3355:
3353:
3350:
3348:
3347:Pyrrobutamine
3345:
3343:
3340:
3338:
3335:
3333:
3330:
3328:
3325:
3323:
3320:
3318:
3315:
3313:
3310:
3308:
3305:
3303:
3300:
3298:
3295:
3293:
3290:
3288:
3285:
3283:
3280:
3278:
3275:
3273:
3272:Methapyrilene
3270:
3268:
3267:Methafurylene
3265:
3263:
3260:
3258:
3255:
3253:
3250:
3248:
3245:
3243:
3240:
3238:
3235:
3233:
3230:
3228:
3225:
3223:
3220:
3218:
3215:
3213:
3210:
3208:
3205:
3203:
3200:
3198:
3195:
3193:
3190:
3188:
3185:
3183:
3180:
3178:
3175:
3173:
3170:
3168:
3165:
3163:
3160:
3158:
3155:
3153:
3150:
3148:
3145:
3143:
3140:
3138:
3135:
3133:
3130:
3128:
3125:
3123:
3120:
3118:
3115:
3113:
3110:
3108:
3105:
3103:
3100:
3098:
3095:
3093:
3090:
3088:
3085:
3083:
3080:
3078:
3075:
3073:
3072:Carbinoxamine
3070:
3068:
3065:
3063:
3060:
3058:
3055:
3053:
3050:
3048:
3045:
3043:
3040:
3038:
3035:
3033:
3030:
3028:
3025:
3023:
3020:
3018:
3015:
3012:
3011:
3009:
3005:
2999:
2996:
2994:
2988:
2986:
2983:
2981:
2978:
2976:
2973:
2971:
2968:
2967:
2965:
2961:
2958:
2956:
2949:
2945:
2942:
2935:
2930:
2928:
2923:
2921:
2916:
2915:
2912:
2908:
2906:
2901:
2876:
2872:
2868:
2862:
2846:
2842:
2838:
2834:
2830:
2826:
2822:
2818:
2811:
2803:
2799:
2794:
2789:
2785:
2781:
2777:
2773:
2769:
2762:
2754:
2750:
2745:
2740:
2735:
2730:
2726:
2722:
2718:
2711:
2703:
2699:
2694:
2689:
2684:
2679:
2675:
2671:
2667:
2660:
2658:
2649:
2645:
2640:
2635:
2631:
2627:
2623:
2619:
2615:
2608:
2606:
2597:
2593:
2588:
2583:
2579:
2575:
2571:
2567:
2563:
2556:
2554:
2545:
2541:
2536:
2531:
2526:
2521:
2517:
2513:
2509:
2502:
2486:
2481:
2476:
2472:
2468:
2461:
2445:
2441:
2437:
2431:
2415:
2411:
2407:
2401:
2395:
2390:
2374:
2370:
2364:
2348:
2344:
2338:
2330:
2326:
2321:
2316:
2312:
2308:
2304:
2297:
2281:
2277:
2271:
2258:
2252:
2244:
2240:
2236:
2232:
2228:
2224:
2220:
2216:
2209:
2201:
2197:
2193:
2189:
2185:
2181:
2177:
2173:
2165:
2157:
2153:
2148:
2143:
2139:
2135:
2131:
2127:
2123:
2116:
2108:
2104:
2100:
2096:
2092:
2088:
2081:
2073:
2069:
2064:
2059:
2054:
2049:
2045:
2041:
2037:
2030:
2014:
2010:
2009:www.webmd.com
2006:
2000:
1984:
1980:
1976:
1970:
1962:
1958:
1954:
1950:
1946:
1942:
1935:
1927:
1923:
1919:
1915:
1911:
1907:
1904:(5): 457–60.
1903:
1899:
1892:
1884:
1880:
1875:
1870:
1867:(11): 967–9.
1866:
1862:
1858:
1851:
1843:
1839:
1834:
1829:
1825:
1821:
1817:
1810:
1802:
1798:
1793:
1788:
1784:
1780:
1777:(3): 379–86.
1776:
1772:
1768:
1761:
1753:
1749:
1745:
1741:
1737:
1733:
1730:(6): 527–43.
1729:
1725:
1718:
1710:
1706:
1702:
1698:
1693:
1688:
1684:
1680:
1676:
1669:
1661:
1657:
1653:
1649:
1642:
1634:
1630:
1626:
1622:
1617:
1612:
1609:(6): 469–74.
1608:
1604:
1600:
1593:
1585:
1581:
1576:
1571:
1567:
1563:
1560:(4): 477–81.
1559:
1555:
1551:
1544:
1536:
1532:
1528:
1524:
1520:
1516:
1513:(4): 435–40.
1512:
1508:
1501:
1493:
1489:
1485:
1481:
1474:
1458:
1454:
1450:
1444:
1428:
1424:
1420:
1414:
1398:
1394:
1392:9783527607495
1388:
1384:
1383:
1375:
1367:
1365:9780857113382
1361:
1357:
1351:
1349:
1332:
1328:
1324:
1318:
1316:
1314:
1312:
1310:
1308:
1291:
1287:
1283:
1277:
1261:
1257:
1253:
1247:
1245:
1243:
1241:
1239:
1222:
1218:
1214:
1208:
1206:
1201:
1193:
1185:
1183:
1182:schizophrenia
1173:
1171:
1167:
1163:
1159:
1155:
1151:
1147:
1132:
1130:
1126:
1121:
1119:
1115:
1105:
1103:
1098:
1096:
1092:
1087:
1085:
1081:
1077:
1072:
1070:
1066:
1062:
1058:
1054:
1044:
1041:
1034:, the first H
1033:
1023:
1021:
1017:
1009:
1005:
991:
989:
985:
980:
978:
974:
970:
966:
956:
944:
940:
937:
933:
930:
926:
925:
920:
918:
914:
911:
907:
905:
901:
897:
895:
891:
887:
884:
881:
880:
874:
868:
863:
861:
860:breastfeeding
857:
853:
849:
844:
842:
838:
834:
830:
826:
822:
818:
810:
806:
796:
789:
780:
775:
774:
771:
764:
755:
754:
751:
744:
737:
733:
732:
730:
727:
722:
715:
713:
709:
676:
674:
670:
665:
661:
657:
654:
652:
650:ECHA InfoCard
646:
638:
634:
633:DTXSID5023039
630:
629:
627:
618:
614:
606:
605:RCSB PDB
600:
595:
594:
592:
590:
586:
579:
575:
574:
572:
570:
566:
559:
555:
554:
552:
550:
546:
539:
535:
534:
532:
530:
526:
519:
515:
514:
512:
510:
506:
499:
495:
494:
492:
490:
486:
479:
475:
474:
472:
470:
466:
459:
455:
454:
452:
450:
446:
439:
435:
434:
432:
425:
421:
414:
410:
409:
407:
405:
401:
393:
388:
387:
384:
377:
372:
368:
365:
363:
359:
356:2.5–3.5 hours
355:
353:
346:
342:
340:
336:
332:
330:
326:
322:
318:
307:
297:
294:
284:
281:
271:
270:
268:
266:
262:
257:
249:
244:
241:
240:
238:
236:
232:
229:
225:
222:
220:
214:
208:
199:
198:
196:
194:
188:
181:
176:
167:
166:
164:
162:
158:
154:
150:
148:
144:
140:
136:
134:
130:
126:
122:
120:
116:
110:
72:
70:Pronunciation
68:
65:Clinical data
63:
59:
54:
50:
45:
37:
33:
19:
4851:
4848:
4814:Combinations
4780:Sulglicotide
4720:Alginic acid
4638:Pantoprazole
4628:Lansoprazole
4618:Esomeprazole
4608:Azeloprazole
4601:("-prazole")
4533:
4499:peptic ulcer
4416:Thioperamide
4320:Thioperamide
4260:Clobenpropit
4181:Immethridine
4084:Ramixotidine
4054:Niperotidine
4019:Isolamtidine
4013:
3979:Bisfentidine
3888:Trelnarizine
3868:Flotrenizine
3849:
3838:thioridazine
3830:perphenazine
3822:fluphenazine
3818:flupenthixol
3804:trimipramine
3768:clomipramine
3764:butriptyline
3750:oxaprotiline
3679:paliperidone
3651:aripiprazole
3643:
3587:Piclopastine
3517:Latrepirdine
3507:Flezelastine
3502:Fexofenadine
3487:Efletirizine
3393:
3387:Triprolidine
3377:Tolpropamine
3372:Thonzylamine
3367:Thiazinamium
3342:Propiomazine
3337:Promethazine
3307:Phenindamine
3287:Orphenadrine
3277:Methdilazine
3242:Isothipendyl
3192:Etodroxizine
3122:Cloperastine
3013:
2897:
2879:. Retrieved
2870:
2867:"Famotidine"
2861:
2849:. Retrieved
2824:
2820:
2810:
2775:
2771:
2761:
2724:
2720:
2710:
2673:
2669:
2621:
2617:
2569:
2565:
2515:
2511:
2501:
2491:20 September
2489:. Retrieved
2470:
2460:
2448:. Retrieved
2439:
2430:
2418:. Retrieved
2410:Medline Plus
2409:
2406:"Famotidine"
2400:
2389:
2377:. Retrieved
2373:the original
2363:
2351:. Retrieved
2347:the original
2337:
2310:
2306:
2296:
2284:. Retrieved
2280:the original
2270:
2251:
2218:
2214:
2208:
2175:
2171:
2164:
2129:
2125:
2115:
2090:
2086:
2080:
2046:(4): 87–93.
2043:
2039:
2029:
2017:. Retrieved
2008:
1999:
1987:. Retrieved
1978:
1969:
1944:
1940:
1934:
1901:
1897:
1891:
1864:
1860:
1850:
1826:(4): 404–6.
1823:
1819:
1809:
1774:
1770:
1760:
1727:
1723:
1717:
1682:
1678:
1668:
1654:(2): 18–22.
1651:
1647:
1641:
1606:
1602:
1592:
1557:
1553:
1543:
1510:
1506:
1500:
1486:(1): 153–6.
1483:
1479:
1473:
1461:. Retrieved
1452:
1443:
1431:. Retrieved
1422:
1413:
1401:. Retrieved
1381:
1374:
1355:
1335:. Retrieved
1326:
1294:. Retrieved
1285:
1276:
1264:. Retrieved
1255:
1225:. Retrieved
1216:
1191:
1179:
1143:
1122:
1111:
1099:
1088:
1073:
1050:
1029:
1026:Interactions
1008:proton pumps
997:
981:
973:constipation
962:
959:Side effects
953:
922:
877:Medical uses
864:
845:
821:stomach acid
808:
804:
803:
792:
391:
349:Elimination
265:Legal status
259:Legal status
161:License data
36:
4876:from market
4785:Telenzepine
4760:Pirenzepine
4755:Lesogaberan
4750:Irsogladine
4715:Acetoxolone
4672:("-prazan")
4658:Timoprazole
4648:Rabeprazole
4643:Picoprazole
4583:Misoprostol
4576:("-prost-")
4522:("-tidine")
4520:antagonists
4401:JNJ-7777120
4394:Antagonists
4305:PF-03654746
4300:NNC 38-1049
4295:JNJ-5207852
4280:Impentamine
4245:Betahistine
4208:Antagonists
4161:Cipralisant
4124:Zolantidine
4114:Venritidine
4049:Mifentidine
3994:Dalcotidine
3972:Antagonists
3950:Impromidine
3878:Napactadine
3842:thiothixene
3792:lofepramine
3772:desipramine
3746:mirtazapine
3738:maprotiline
3691:ziprasidone
3687:risperidone
3671:iloperidone
3627:Terfenadine
3622:Temelastine
3572:Olopatadine
3562:Noberastine
3552:Mizolastine
3547:Mebhydrolin
3542:Mapinastine
3532:Linetastine
3447:Carebastine
3432:Bepotastine
3417:Bamirastine
3397:Acrivastine
3357:Thenalidine
3322:Pimethixene
3312:Pheniramine
3297:Oxomemazine
3262:Mequitazine
3252:Medrylamine
3232:Hydroxyzine
3212:Flunarizine
3207:Fenethazine
3202:Etymemazine
3167:Dimetindene
3142:Decloxizine
3117:Clocinizine
3112:Clobenzepam
3102:Cinnarizine
3047:Bepotastine
3022:Alimemazine
3007:Antagonists
2975:Betahistine
2778:: 158–170.
2727:: 1202696.
1861:Anaesthesia
1724:Drug Safety
1158:vagus nerve
1006:stimulates
917:esophagitis
813:histamine H
719: g·mol
656:100.116.793
374:Identifiers
228:intravenous
147:MedlinePlus
119:Trade names
4960:Thioethers
4950:Sulfamides
4940:Guanidines
4929:Categories
4849:See also:
4805:Zolimidine
4775:Sucralfate
4770:Rebamipide
4765:Proglumide
4694:Vonoprazan
4689:Soraprazan
4684:Revaprazan
4679:Linaprazan
4633:Omeprazole
4623:Ilaprazole
4559:Roxatidine
4554:Ranitidine
4549:Nizatidine
4539:Lafutidine
4534:Famotidine
4529:Cimetidine
4497:Drugs for
4421:Toreforant
4411:Seliforant
4375:-Histidine
4310:Pitolisant
4290:Irdabisant
4275:GSK-189254
4255:Ciproxifan
4250:Burimamide
4194:Methimepip
4189:-Histidine
4109:Tuvatidine
4099:Sufotidine
4094:Roxatidine
4089:Ranitidine
4074:Pibutidine
4069:Oxmetidine
4059:Nizatidine
4039:Lupitidine
4024:Lafutidine
4014:Famotidine
4009:Etintidine
4004:Ebrotidine
3999:Donetidine
3989:Cimetidine
3984:Burimamide
3958:-Histidine
3883:Tagorizine
3873:GSK1004723
3863:Elbanizine
3858:Belarizine
3784:imipramine
3712:nefazodone
3683:quetiapine
3675:olanzapine
3632:Vapitadine
3602:Rupatadine
3582:Pibaxizine
3537:Loratadine
3497:Epinastine
3492:Emedastine
3457:Clemastine
3452:Cetirizine
3442:Cabastinen
3427:Bepiastine
3422:Barmastine
3412:Azelastine
3407:Astemizole
3402:Alinastine
3332:Pipoxizine
3182:Doxylamine
3147:Deptropine
3137:Dacemazine
3107:Clemastine
3087:Chlorothen
3067:Captodiame
3027:Antazoline
2993:-Histidine
2944:modulators
2905:Famotidine
2851:11 January
2774:(Review).
2624:: 111425.
2518:: 633680.
2379:31 January
2286:31 October
1196:References
1162:mast cells
1069:cimetidine
1065:ranitidine
1032:cimetidine
1016:antagonist
929:omeprazole
805:Famotidine
724:3D model (
712:Molar mass
589:PDB ligand
558:CHEBI:4975
518:5QZO15J2Z8
489:ChemSpider
449:IUPHAR/BPS
413:76824-35-6
404:CAS Number
383:IUPAC name
295:(GSL, OTC)
180:Famotidine
41:Famotidine
4955:Thiazoles
4886:Phase III
4874:Withdrawn
4795:Troxipide
4790:Teprenone
4745:Gefarnate
4740:Cetraxate
4588:Enprostil
4574:analogues
4503:GERD/GORD
4406:Mianserin
4367:Histamine
4315:SCH-79687
4270:Enerisant
4265:Conessine
4166:Histamine
4119:Xaltidine
4104:Tiotidine
4064:Osutidine
4044:Metiamide
4029:Lamtidine
3940:Histamine
3925:Amthamine
3893:Trenizine
3788:iprindole
3742:mianserin
3730:amoxapine
3716:trazodone
3667:clozapine
3655:asenapine
3637:Zepastine
3617:Talastine
3607:Setastine
3597:Rocastine
3577:Perastine
3567:Octastine
3557:Moxastine
3512:Ketotifen
3477:Dorastine
3462:Clemizole
3437:Bilastine
3352:Talastine
3327:Piperoxan
3302:Perlapine
3292:Oxatomide
3282:Moxastine
3247:Meclozine
3187:Embramine
3127:Cyclizine
3062:Buclizine
3052:Bromazine
3032:Azatadine
2980:Histamine
2676:(1): 57.
2440:Drugs.com
2200:230485193
1463:30 August
1433:30 August
1327:Drugs.com
1217:Drugs.com
1150:TNF-alpha
1125:ibuprofen
1061:imidazole
1020:histamine
969:dizziness
883:heartburn
856:pregnancy
854:. Use in
848:pneumonia
578:ChEMBL902
362:Excretion
351:half-life
217:Routes of
191:Pregnancy
139:Monograph
133:Drugs.com
4935:Amidines
4919:Medicine
4442:See also
4426:VUF-6002
4385:VUF-8430
4350:Agonists
4325:VUF-5681
4240:Bavisant
4220:A-423579
4215:A-349821
4199:Proxyfan
4149:Agonists
3935:Dimaprit
3930:Betazole
3918:Agonists
3853:Azanator
3826:loxapine
3734:loxapine
3695:zotepine
3482:Ebastine
3037:Bamipine
2963:Agonists
2875:Archived
2845:Archived
2841:24107771
2802:35397357
2753:37529714
2744:10388239
2702:35578169
2648:37399740
2639:10292911
2596:36462586
2566:J Infect
2544:33833683
2485:Archived
2450:28 April
2444:Archived
2436:"Duexis"
2420:21 March
2414:Archived
2243:20462864
2192:33394214
2178:(1): 4.
2156:21770762
2107:15135720
2072:23675554
2013:Archived
1983:Archived
1926:44356956
1801:22186979
1752:41990751
1744:10392669
1709:24690061
1701:15943841
1660:15106408
1633:25818901
1625:14708410
1535:22115962
1527:10452673
1492:10036954
1457:Archived
1453:ClinCalc
1427:Archived
1423:ClinCalc
1397:Archived
1331:Archived
1290:Archived
1286:DailyMed
1260:Archived
1256:DailyMed
1221:Archived
1140:COVID-19
1135:Research
977:diarrhea
965:headache
852:seizures
837:by mouth
795:(verify)
469:DrugBank
235:ATC code
224:By mouth
206: B1
193:category
175:DailyMed
4235:AZD5213
4230:ABT-652
4225:ABT-239
4176:Immepip
3963:UR-AK49
3812:(e.g.,
3780:doxepin
3758:(e.g.,
3728:(e.g.,
3706:(e.g.,
3649:(e.g.,
3644:Others:
2998:UR-AK49
2793:8956349
2693:9109205
2670:Mol Med
2587:9711899
2535:8021898
2471:Science
2329:2857672
2235:8117350
2147:3157302
2063:3653016
2019:2 March
1989:2 March
1961:8618369
1918:1887750
1883:1750602
1842:1419452
1792:3321505
1584:7489931
1575:1382896
1337:3 March
1266:6 March
1227:3 March
1118:antacid
1095:antacid
1080:Schwarz
1047:History
1030:Unlike
890:gastric
673:Formula
478:DB00927
424:PubChem
312:Rx-only
308: /
251:)
245: (
243:A02BA03
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153:a687011
4905:Portal
4869:WHO-EM
4703:Others
4380:OUP-16
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1296:6 July
971:, and
912:(GERD)
871:
839:or by
831:, and
809:Pepcid
750:SMILES
717:337.44
569:ChEMBL
538:D00318
367:Kidney
343:15–20%
310:
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291:
278:
173:
113:
2871:PetMD
2239:S2CID
2196:S2CID
1922:S2CID
1748:S2CID
1705:S2CID
1629:S2CID
1531:S2CID
1403:7 May
1176:Other
936:NSAID
770:InChI
726:JSmol
596:FO9 (
549:ChEBI
18:Dinul
4571:(E)/
4507:A02B
4501:and
3945:HTMT
2985:HTMT
2883:2015
2853:2024
2837:PMID
2798:PMID
2749:PMID
2698:PMID
2644:PMID
2592:PMID
2540:PMID
2493:2022
2452:2020
2422:2018
2381:2009
2355:2015
2325:PMID
2288:2009
2231:PMID
2188:PMID
2152:PMID
2103:PMID
2068:PMID
2021:2019
1991:2019
1957:PMID
1941:JAMA
1914:PMID
1879:PMID
1838:PMID
1797:PMID
1740:PMID
1697:PMID
1656:PMID
1621:PMID
1580:PMID
1523:PMID
1488:PMID
1465:2024
1435:2024
1405:2020
1387:ISBN
1360:ISBN
1339:2019
1298:2022
1268:2021
1229:2019
1154:IL-6
1152:and
902:and
892:and
850:and
599:PDBe
529:KEGG
509:UNII
498:3208
458:7074
438:3325
323:data
129:AHFS
2829:doi
2788:PMC
2780:doi
2739:PMC
2729:doi
2688:PMC
2678:doi
2634:PMC
2626:doi
2622:172
2582:PMC
2574:doi
2530:PMC
2520:doi
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2315:doi
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2180:doi
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2134:doi
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1949:doi
1945:275
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1828:doi
1787:PMC
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