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Dimercaprol

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796:. However, it is not necessarily the treatment of choice for toxicity to these metals. Dimercaprol has been used as an adjunct in the treatment of the acute encephalopathy of lead toxicity. It is a potentially toxic drug, and its use may be accompanied by multiple side effects. Although treatment with dimercaprol will increase the excretion of cadmium, there is a concomitant increase in renal cadmium concentration, so that its use in case of cadmium toxicity is to be avoided. It does, however, remove inorganic mercury from the kidneys; but is not useful in the treatment of alkylmercury or phenylmercury toxicity. Dimercaprol also enhances the toxicity of 426: 403: 38: 29: 3369: 2358: 3303: 2579: 2569: 2394: 738:
complex that inhibits the affected enzyme's activity. Dimercaprol competes with the thiol groups for binding the metal ion, which is then excreted in the urine.
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Mückter H, Liebl B, Reichl FX, Hunder G, Walther U, Fichtl B (August 1997). "Are we ready to replace dimercaprol (BAL) as an arsenic antidote?".
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Leggio L, Addolorato G, Abenavoli L, Gasbarrini G (2005). "Wilson's disease: clinical, genetic and pharmacological findings".
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and other tissues. Dimercaprol is a copper chelating agent that has been approved by the FDA to treat Wilson's disease.
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and a tendency to concentrate arsenic in some organs. Other drawbacks include the need to administer it by painful
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for lead or arsenic poisoning, and it is an essential drug. It is also used as an antidote to the chemical weapon
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Albulescu LO, Hale MS, Ainsworth S, Alsolaiss J, Crittenden E, Calvete JJ, et al. (May 2020).
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The prefixes 'mercapto' (–SH), and 'hydroseleno' or selenyl (–SeH), etc. are no longer recommended.
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Nomenclature of Organic Chemistry : IUPAC Recommendations and Preferred Names 2013 (Blue Book)
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Goldman M, Dacre JC (1989). "Lewisite: Its Chemistry, Toxicology, and Biological Effects".
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as it is typically formulated as a suspension in peanut oil. It is unclear if use in
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World Health Organization model list of essential medicines: 21st list 2019
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Peters RA, Stocken LA, Thompson RH (1945). "British anti-lewisite (BAL)".
1316: 1273: 1121: 612:, although the evidence for those uses is not very strong. It is given by 3308: 3278: 3258: 3208: 3083: 3078: 3063: 3033: 2815: 2775: 2770: 2720: 2715: 2700: 2539: 2499: 2404: 2263: 2227: 2194: 2189: 1946: 1931: 1617: 1577: 1539: 708: 2145: 1085: 291: 3288: 3248: 3193: 3183: 3123: 3108: 3093: 3073: 3048: 3043: 3023: 3018: 2975: 2965: 2930: 2905: 2885: 2850: 2829: 2785: 2760: 2544: 2509: 2494: 2489: 2458: 2419: 2399: 2001: 1936: 1906: 1690: 1670: 1660: 1544: 1489: 1011: 581: 468: 302: 37: 3213: 3203: 3198: 3188: 3173: 3158: 3103: 3058: 3028: 2890: 2870: 2795: 2735: 2730: 2599: 2529: 2519: 2464: 2146: 1655: 1612: 1597: 1567: 1514: 1381: 1042:
Antimicrobial Drugs: Chronicle of a Twentieth Century Medical Triumph
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International Journal of Environmental Research and Public Health
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The original name of dimercaprol reflects its origins as a
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and some other heavy metals act by chelating with adjacent
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International Journal of Immunopathology and Pharmacology
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Skeletal formula and ball and stick model of dimercaprol
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World Health Organization's List of Essential Medicines
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Reviews of Environmental Contamination and Toxicology
975:. The American Society of Health-System Pharmacists. 760:Dimercaprol has been found to form stable chelates 623:, pain at the site of the injection, vomiting, and 3381: 1340: 899:. Jaypee Brothers Publishers. 2013. p. 70. 270: 1098: 1096: 1001:(2009). Stuart MC, Kouimtzi M, Hill SR (eds.). 245: 824:, with the first synthesis in July 1940 as an 3410:World Health Organization essential medicines 2352: 2131: 1442: 1102: 816:secretly developed by British biochemists at 699:Dimercaprol also shows effectiveness against 1245: 1093: 115: 2635: 1336: 1334: 1280: 1239: 764:with many other metals including inorganic 741:Dimercaprol is itself toxic, with a narrow 670:. Nonetheless, because it can have serious 2686:Allopregnanedione (5α-dihydroprogesterone) 2359: 2345: 2138: 2124: 1449: 1435: 967: 965: 963: 961: 959: 957: 955: 734:residues on metabolic enzymes, creating a 662:Dimercaprol has long been the mainstay of 424: 401: 310: 36: 27: 1222: 1130: 1120: 1084: 1067: 1065: 1035: 1010: 1005:. World Health Organization. p. 62. 703:by potently antagonizing the activity of 554:InChI=1S/C3H8OS2/c4-1-3(6)2-5/h3-6H,1-2H2 330: 2384:Tooltip Constitutive androstane receptor 1331: 913: 627:. It is not recommended for people with 952: 635:is safe for the baby. Dimercaprol is a 397: 290: 3382: 3139:Pregnanedione (5β-dihydroprogesterone) 2525:Pregnanedione (5β-dihydroprogesterone) 1062: 991: 722: 415: 2340: 2119: 1456: 1430: 1079:. Geneva: World Health Organization. 979:from the original on 21 December 2016 850:2,3-Dimercapto-1-propanesulfonic acid 370: 178: 106: 88: 1422:. U.S. National Library of Medicine. 518:393 °C (739 °F) at 2.0 kPa 151: 1289:Human & Experimental Toxicology 350: 261: 13: 1250:. Vol. 110. pp. 75–115. 1103:Flora SJ, Pachauri V (July 2010). 646:Dimercaprol was first made during 14: 3421: 1408: 1105:"Chelation in metal intoxication" 584:used to treat acute poisoning by 3367: 1349:from the original on 2009-02-02. 1058:from the original on 2016-12-20. 449: 1353: 657: 559:Key:WQABCVAJNWAXTE-UHFFFAOYSA-N 2691:Allopregnanolone (brexanolone) 1203:Science Translational Medicine 1190: 1147: 1029: 925:The Royal Society of Chemistry 887: 643:. It has a very pungent odor. 458: 455: 443: 1: 3346:Receptor/signaling modulators 3304:Tropanyl 3,5-dimethulbenzoate 3154:Pregnenolone 16α-carbonitrile 1341:Tabangcura Jr D, Daubert GP. 880: 749:Serious side effects include 1215:10.1126/scitranslmed.aay8314 619:Common side effects include 228:2,3-Bis(sulfanyl)propan-1-ol 7: 2881:Dodecylbenzenesulfonic acid 2640:Tooltip Pregnane X receptor 2368:Xenobiotic-sensing receptor 1256:10.1007/978-1-4684-7092-5_2 1044:. OUP Oxford. p. 281. 933:10.1039/9781849733069-FP001 843: 10: 3426: 1309:10.1177/096032719701600807 1168:10.1177/039463200501800102 807: 600:. It may also be used for 433:Chemical and physical data 3337: 2633: 2377: 2297: 2256: 2238: 2208: 2180: 2162: 2076: 2046: 2034:Prednisolone/promethazine 2015:Methylthioninium chloride 1993: 1945: 1915: 1884: 1866: 1819: 1796: 1789: 1750: 1732: 1714: 1703: 1679: 1636: 1576: 1553: 1528: 1503: 1480: 1469: 1073:World Health Organization 999:World Health Organization 641:binding with heavy metals 542: 522: 512: 502: 480: 467: 437: 432: 413: 381: 361: 341: 321: 301: 281: 256: 236: 216: 211: 201: 193: 168: 163: 138: 126: 96: 78: 72:2,3-Dimercaptopropan-1-ol 62: 52: 47: 35: 26: 3264:Testosterone isocaproate 3179:Reverse triiodothyronine 1003:WHO Model Formulary 2008 820:in the beginning of the 2656:17α-Hydroxyprogesterone 2651:17α-Hydroxypregnenolone 1420:Drug Information Portal 1343:"British anti-Lewisite" 855:Dimercaptosuccinic acid 747:intramuscular injection 614:injection into a muscle 2027:Potassium permanganate 1683:neuromuscular blockade 1038:"Antiprotozoal Agents" 838:chemical warfare agent 66:2,3-Dimercaptopropanol 2395:6,7-Dimethylesculetin 1829:4-Dimethylaminophenol 1122:10.3390/ijerph7072745 927:. 2014. p. 697. 896:Poisoning in Children 870:Heavy metal poisoning 692:builds up inside the 574:British anti-Lewisite 68:British Anti-Lewisite 2982:Hypericum perforatum 2971:Hetacillin potassium 1917:Paracetamol toxicity 1761:direct Xa inhibitors 1482:Alcohol intoxication 1036:Greenwood D (2008). 74:British antilewisite 2811:Cyproterone acetate 2711:Amlodipine besylate 1374:1945Natur.156..616P 1301:1997HETox..16..460M 723:Mechanism of action 621:high blood pressure 23: 3284:Thonzonium bromide 3039:Methylprednisolone 2840:prasterone sulfate 2324:Never to phase III 2103:Never to phase III 1900:Primary alcohols: 1858:Sodium thiosulfate 1742:Digoxin immune fab 712:metalloproteinases 70:2,3-Dithiopropanol 19: 3355: 3354: 2989:Indinavir sulfate 2696:Alpha-Lipoic acid 2671:Δ-Androstenedione 2661:Δ-Androstenedione 2334: 2333: 2151:chelation therapy 2113: 2112: 2042: 2041: 1876:Calcium gluconate 1868:Hydrofluoric acid 1821:Cyanide poisoning 1798:Arsenic poisoning 1785: 1784: 1699: 1698: 1368:(3969): 616–619. 1265:978-1-4684-7094-9 1051:978-0-19-953484-5 1022:978-92-4-154765-9 942:978-0-85404-182-4 906:978-93-5025-773-9 832:, a now-obsolete 818:Oxford University 743:therapeutic range 664:chelation therapy 610:bismuth poisoning 567: 566: 493:Interactive image 383:CompTox Dashboard 182: 109: 16:Chemical compound 3417: 3400:Chelating agents 3390:Primary alcohols 3372: 3371: 3370: 3363: 3274:Thiamylal sodium 3009:γ-linolenic acid 3005:α-Linolenic acid 3003:Linolenic acid: 2994:Lasalocid sodium 2984:(St John's wort) 2876:Docusate calcium 2806:Cyclophosphamide 2681:Allopregnanediol 2666:Δ-Androstenediol 2641: 2637: 2595:Ethinylestradiol 2445:Cyclophosphamide 2385: 2381: 2361: 2354: 2347: 2338: 2337: 2147:Chelating agents 2140: 2133: 2126: 2117: 2116: 2008:Potassium iodide 1834:Hydroxocobalamin 1794: 1793: 1734:Digoxin toxicity 1712: 1711: 1478: 1477: 1451: 1444: 1437: 1428: 1427: 1423: 1402: 1401: 1382:10.1038/156616a0 1357: 1351: 1350: 1338: 1329: 1328: 1284: 1278: 1277: 1243: 1237: 1236: 1226: 1194: 1188: 1187: 1151: 1145: 1144: 1134: 1124: 1115:(7): 2745–2788. 1100: 1091: 1090: 1088: 1069: 1060: 1059: 1033: 1027: 1026: 1014: 995: 989: 988: 986: 984: 969: 950: 949: 917: 911: 910: 891: 686:genetic disorder 682:Wilson's disease 629:peanut allergies 495: 475: 460: 457: 451: 445: 428: 417: 406: 405: 391: 389: 374: 354: 334: 314: 294: 274: 264: 263: 249: 180: 177: 155: 119: 108: 105: 92: 40: 31: 24: 22: 18: 3425: 3424: 3420: 3419: 3418: 3416: 3415: 3414: 3380: 3379: 3378: 3368: 3366: 3358: 3356: 3351: 3333: 3234:Suberoylanilide 2951:Fluorometholone 2846:Dibunate sodium 2726:Aurothioglucose 2639: 2629: 2565:3,17β-Estradiol 2383: 2373: 2365: 2335: 2330: 2329: 2314:Clinical trials 2293: 2252: 2234: 2204: 2176: 2158: 2144: 2114: 2109: 2108: 2093:Clinical trials 2072: 2066:Syrup of ipecac 2038: 2021:oxidizing agent 1989: 1941: 1920:(Acetaminophen) 1919: 1911: 1892: 1891:Ethylene glycol 1889: 1880: 1862: 1815: 1781: 1746: 1728: 1706: 1695: 1681: 1675: 1638:Opioid overdose 1632: 1584: 1583:Organophosphate 1581: 1572: 1549: 1531: 1524: 1506: 1499: 1472: 1465: 1455: 1414: 1411: 1406: 1405: 1358: 1354: 1339: 1332: 1285: 1281: 1266: 1244: 1240: 1195: 1191: 1152: 1148: 1101: 1094: 1070: 1063: 1052: 1034: 1030: 1023: 996: 992: 982: 980: 971: 970: 953: 943: 919: 918: 914: 907: 893: 892: 888: 883: 846: 810: 725: 672:adverse effects 660: 650:. It is on the 563: 560: 555: 550: 549: 538: 535: 530: 529: 508:1.239 g/cm 498: 473: 463: 454: 448: 409: 385: 377: 357: 337: 317: 297: 277: 260: 252: 232: 229: 224: 223: 195:Pharmacokinetic 189: 159: 129: 122: 73: 71: 69: 67: 43: 17: 12: 11: 5: 3423: 3413: 3412: 3407: 3402: 3397: 3392: 3377: 3376: 3353: 3352: 3350: 3349: 3342: 3338: 3335: 3334: 3332: 3331: 3326: 3317: 3316: 3311: 3306: 3301: 3299:Troleandomycin 3296: 3291: 3286: 3281: 3276: 3271: 3266: 3261: 3256: 3251: 3246: 3241: 3236: 3231: 3226: 3221: 3219:Spironolactone 3216: 3211: 3206: 3201: 3196: 3191: 3186: 3181: 3176: 3171: 3166: 3161: 3156: 3151: 3146: 3141: 3136: 3131: 3126: 3121: 3116: 3111: 3106: 3101: 3096: 3091: 3089:Norelgestromin 3086: 3081: 3076: 3071: 3066: 3061: 3056: 3051: 3046: 3041: 3036: 3031: 3026: 3021: 3016: 3011: 3001: 2996: 2991: 2986: 2978: 2973: 2968: 2963: 2958: 2953: 2948: 2946:Flucloxacillin 2943: 2938: 2933: 2928: 2923: 2918: 2913: 2908: 2903: 2898: 2893: 2888: 2883: 2878: 2873: 2868: 2863: 2858: 2853: 2848: 2843: 2833: 2823: 2818: 2813: 2808: 2803: 2801:Corticosterone 2798: 2793: 2788: 2783: 2778: 2773: 2768: 2766:Chlorpromazine 2763: 2758: 2753: 2748: 2743: 2738: 2733: 2728: 2723: 2718: 2713: 2708: 2703: 2698: 2693: 2688: 2683: 2678: 2673: 2668: 2663: 2658: 2653: 2644: 2642: 2631: 2630: 2628: 2627: 2622: 2617: 2612: 2607: 2602: 2597: 2592: 2587: 2585:17-Androstanol 2582: 2580:3β-Androstanol 2577: 2575:3α-Androstenol 2572: 2570:3α-Androstanol 2567: 2558: 2557: 2552: 2547: 2542: 2537: 2532: 2527: 2522: 2517: 2512: 2507: 2502: 2497: 2492: 2487: 2482: 2477: 2472: 2467: 2462: 2452: 2447: 2442: 2437: 2432: 2427: 2425:Chlorpromazine 2422: 2417: 2412: 2407: 2402: 2397: 2388: 2386: 2375: 2374: 2364: 2363: 2356: 2349: 2341: 2332: 2331: 2328: 2327: 2326: 2325: 2322: 2311: 2305: 2299: 2298: 2295: 2294: 2292: 2291: 2286: 2281: 2276: 2271: 2266: 2260: 2258: 2254: 2253: 2251: 2250: 2244: 2242: 2236: 2235: 2233: 2232: 2231: 2230: 2220: 2214: 2212: 2206: 2205: 2203: 2202: 2197: 2192: 2186: 2184: 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276: 275: 267: 265: 254: 253: 251: 250: 242: 240: 234: 233: 231: 230: 227: 219: 218: 217: 214: 213: 209: 208: 205: 199: 198: 191: 190: 188: 187: 174: 172: 166: 165: 161: 160: 158: 157: 144: 142: 136: 135: 132: 130:administration 124: 123: 121: 120: 102: 100: 94: 93: 86: 76: 75: 64: 60: 59: 56: 50: 49: 45: 44: 41: 33: 32: 15: 9: 6: 4: 3: 2: 3422: 3411: 3408: 3406: 3403: 3401: 3398: 3396: 3393: 3391: 3388: 3387: 3385: 3375: 3365: 3364: 3361: 3348: 3347: 3343: 3340: 3339: 3336: 3330: 3327: 3325: 3322: 3319: 3318: 3315: 3312: 3310: 3307: 3305: 3302: 3300: 3297: 3295: 3292: 3290: 3287: 3285: 3282: 3280: 3277: 3275: 3272: 3270: 3267: 3265: 3262: 3260: 3257: 3255: 3252: 3250: 3247: 3245: 3242: 3240: 3239:Sulfisoxazole 3237: 3235: 3232: 3230: 3227: 3225: 3222: 3220: 3217: 3215: 3212: 3210: 3207: 3205: 3202: 3200: 3197: 3195: 3192: 3190: 3187: 3185: 3182: 3180: 3177: 3175: 3172: 3170: 3167: 3165: 3162: 3160: 3157: 3155: 3152: 3150: 3147: 3145: 3142: 3140: 3137: 3135: 3132: 3130: 3127: 3125: 3122: 3120: 3117: 3115: 3114:Phenobarbital 3112: 3110: 3107: 3105: 3102: 3100: 3097: 3095: 3092: 3090: 3087: 3085: 3082: 3080: 3077: 3075: 3072: 3070: 3067: 3065: 3062: 3060: 3057: 3055: 3052: 3050: 3047: 3045: 3042: 3040: 3037: 3035: 3032: 3030: 3027: 3025: 3022: 3020: 3017: 3015: 3012: 3010: 3006: 3002: 3000: 2999:Levothyroxine 2997: 2995: 2992: 2990: 2987: 2985: 2983: 2979: 2977: 2974: 2972: 2969: 2967: 2964: 2962: 2961:Guggulsterone 2959: 2957: 2954: 2952: 2949: 2947: 2944: 2942: 2939: 2937: 2934: 2932: 2929: 2927: 2924: 2922: 2919: 2917: 2914: 2912: 2909: 2907: 2904: 2902: 2899: 2897: 2894: 2892: 2889: 2887: 2884: 2882: 2879: 2877: 2874: 2872: 2869: 2867: 2864: 2862: 2859: 2857: 2856:Dicloxacillin 2854: 2852: 2849: 2847: 2844: 2841: 2837: 2834: 2831: 2827: 2824: 2822: 2821:Dexamethasone 2819: 2817: 2814: 2812: 2809: 2807: 2804: 2802: 2799: 2797: 2794: 2792: 2789: 2787: 2784: 2782: 2779: 2777: 2774: 2772: 2769: 2767: 2764: 2762: 2759: 2757: 2756:Cephaloridine 2754: 2752: 2749: 2747: 2744: 2742: 2739: 2737: 2734: 2732: 2729: 2727: 2724: 2722: 2719: 2717: 2714: 2712: 2709: 2707: 2704: 2702: 2699: 2697: 2694: 2692: 2689: 2687: 2684: 2682: 2679: 2677: 2674: 2672: 2669: 2667: 2664: 2662: 2659: 2657: 2654: 2652: 2649: 2646: 2645: 2643: 2638: 2632: 2626: 2623: 2621: 2618: 2616: 2613: 2611: 2608: 2606: 2603: 2601: 2598: 2596: 2593: 2591: 2588: 2586: 2583: 2581: 2578: 2576: 2573: 2571: 2568: 2566: 2563: 2560: 2559: 2556: 2555:Valproic acid 2553: 2551: 2548: 2546: 2543: 2541: 2538: 2536: 2533: 2531: 2528: 2526: 2523: 2521: 2518: 2516: 2515:Phenobarbital 2513: 2511: 2508: 2506: 2503: 2501: 2498: 2496: 2493: 2491: 2488: 2486: 2483: 2481: 2478: 2476: 2473: 2471: 2468: 2466: 2463: 2460: 2456: 2453: 2451: 2448: 2446: 2443: 2441: 2438: 2436: 2433: 2431: 2428: 2426: 2423: 2421: 2418: 2416: 2415:Carbamazepine 2413: 2411: 2408: 2406: 2403: 2401: 2398: 2396: 2393: 2390: 2389: 2387: 2382: 2376: 2372: 2369: 2362: 2357: 2355: 2350: 2348: 2343: 2342: 2339: 2323: 2321: 2318: 2317: 2315: 2312: 2309: 2306: 2304: 2301: 2300: 2296: 2290: 2287: 2285: 2282: 2280: 2277: 2275: 2272: 2270: 2267: 2265: 2262: 2261: 2259: 2255: 2249: 2248:Prussian blue 2246: 2245: 2243: 2241: 2237: 2229: 2226: 2225: 2224: 2221: 2219: 2216: 2215: 2213: 2211: 2207: 2201: 2198: 2196: 2193: 2191: 2188: 2187: 2185: 2183: 2179: 2173: 2172:Penicillamine 2170: 2169: 2167: 2165: 2161: 2156: 2152: 2148: 2141: 2136: 2134: 2129: 2127: 2122: 2121: 2118: 2102: 2100: 2097: 2096: 2094: 2091: 2088: 2085: 2083: 2080: 2079: 2075: 2067: 2064: 2063: 2062: 2059: 2057: 2054: 2053: 2051: 2049: 2045: 2035: 2032: 2028: 2025: 2024: 2023: 2022: 2018: 2016: 2013: 2009: 2006: 2005: 2004: 2003: 1999: 1998: 1996: 1992: 1987: 1986:Prussian blue 1984: 1982: 1979: 1977: 1974: 1972: 1967: 1964: 1962: 1959: 1957: 1954: 1953: 1952: 1948: 1944: 1938: 1935: 1933: 1930: 1928: 1925: 1924: 1922: 1918: 1914: 1908: 1905: 1903: 1899: 1898: 1896: 1894: 1887: 1883: 1877: 1874: 1873: 1871: 1869: 1865: 1859: 1856: 1852: 1849: 1847: 1844: 1843: 1842: 1841: 1837: 1835: 1832: 1830: 1827: 1826: 1824: 1822: 1818: 1812: 1809: 1807: 1804: 1803: 1801: 1799: 1795: 1792: 1788: 1777: 1773: 1769: 1766: 1762: 1758: 1757: 1755: 1753: 1749: 1743: 1740: 1739: 1737: 1735: 1731: 1725: 1722: 1721: 1719: 1717: 1713: 1710: 1708: 1702: 1692: 1689: 1688: 1686: 1684: 1678: 1672: 1669: 1667: 1664: 1662: 1659: 1657: 1654: 1652: 1649: 1647: 1646:Diprenorphine 1644: 1643: 1641: 1639: 1635: 1629: 1626: 1623: 1619: 1616: 1614: 1611: 1610: 1609: 1606: 1604: 1601: 1599: 1596: 1594: 1591: 1590: 1588: 1586: 1579: 1575: 1569: 1566: 1564: 1563:Physostigmine 1561: 1560: 1558: 1556: 1552: 1546: 1543: 1541: 1538: 1537: 1535: 1533: 1527: 1521: 1518: 1516: 1513: 1512: 1510: 1508: 1502: 1496: 1493: 1491: 1488: 1487: 1485: 1483: 1479: 1476: 1474: 1468: 1463: 1459: 1452: 1447: 1445: 1440: 1438: 1433: 1432: 1429: 1421: 1417: 1416:"Dimercaprol" 1413: 1412: 1399: 1395: 1391: 1387: 1383: 1379: 1375: 1371: 1367: 1363: 1356: 1348: 1344: 1337: 1335: 1326: 1322: 1318: 1314: 1310: 1306: 1302: 1298: 1294: 1290: 1283: 1275: 1271: 1267: 1261: 1257: 1253: 1249: 1242: 1234: 1230: 1225: 1220: 1216: 1212: 1208: 1204: 1200: 1193: 1185: 1181: 1177: 1173: 1169: 1165: 1161: 1157: 1150: 1142: 1138: 1133: 1128: 1123: 1118: 1114: 1110: 1106: 1099: 1097: 1087: 1082: 1078: 1074: 1068: 1066: 1057: 1053: 1047: 1043: 1039: 1032: 1024: 1018: 1013: 1008: 1004: 1000: 994: 978: 974: 973:"Dimercaprol" 968: 966: 964: 962: 960: 958: 956: 948: 944: 938: 934: 930: 926: 923:. Cambridge: 922: 916: 908: 902: 898: 897: 890: 886: 876: 875:Penicillamine 873: 871: 868: 866: 863: 861: 858: 856: 853: 851: 848: 847: 841: 839: 835: 831: 827: 823: 819: 815: 805: 803: 799: 795: 791: 787: 783: 779: 775: 771: 767: 763: 758: 756: 752: 748: 744: 739: 737: 733: 729: 720: 718: 717: 713: 710: 706: 702: 697: 695: 691: 687: 683: 679: 677: 673: 669: 665: 655: 653: 649: 644: 642: 639:and works by 638: 634: 630: 626: 622: 617: 615: 611: 607: 603: 599: 595: 591: 587: 583: 579: 575: 571: 557: 552: 551: 548: 541: 532: 531: 528: 521: 517: 515: 514:Boiling point 511: 507: 505: 501: 494: 490: 489: 487: 484: 479: 472: 470: 466: 442: 440: 436: 431: 427: 423: 420: 418: 416:ECHA InfoCard 412: 404: 400: 399:DTXSID5040461 396: 395: 393: 384: 380: 373: 369: 368: 366: 364: 360: 353: 349: 348: 346: 344: 340: 333: 329: 328: 326: 324: 320: 313: 309: 308: 306: 304: 300: 293: 289: 288: 286: 284: 280: 273: 269: 268: 266: 259: 255: 248: 244: 243: 241: 239: 235: 226: 225: 222: 215: 210: 206: 204: 200: 196: 192: 186: 176: 175: 173: 171: 167: 162: 154: 149: 146: 145: 143: 141: 137: 134:intramuscular 133: 131: 125: 118: 113: 104: 103: 101: 99: 95: 91: 87: 85: 81: 77: 65: 61: 57: 55: 51: 48:Clinical data 46: 39: 34: 30: 25: 3344: 3324:Ketoconazole 3321:Antagonists: 3320: 3294:Troglitazone 3269:Tetracycline 3224:Spiroxatrine 3169:Quingestrone 3164:Progesterone 3149:Pregnenolone 3144:Pregnanolone 3134:Pregnanediol 3129:Prednisolone 3054:Mifepristone 2981: 2956:Griseofulvin 2936:Fenbendazole 2921:Famprofazone 2916:Erythromycin 2911:Epothilone B 2896:Eburnamonine 2860: 2791:Clotrimazole 2781:Clofenvinfos 2716:Antimycotics 2647: 2610:Okadaic acid 2562:Antagonists: 2561: 2550:Troglitazone 2485:Mifepristone 2480:Methoxychlor 2475:Griseofulvin 2470:Ellagic acid 2450:Cypermethrin 2440:Clotrimazole 2391: 2217: 2200:Deferoxamine 2019: 2000: 1975: 1947:Toxic metals 1846:Amyl nitrite 1838: 1805: 1716:Beta blocker 1624: 1555:GHB overdose 1419: 1365: 1361: 1355: 1292: 1288: 1282: 1247: 1241: 1206: 1202: 1192: 1159: 1155: 1149: 1112: 1108: 1086:10665/325771 1076: 1041: 1031: 1002: 993: 981:. Retrieved 946: 920: 915: 895: 889: 822:World War II 811: 761: 759: 755:hypertension 740: 726: 714: 698: 680: 661: 658:Medical uses 648:World War II 645: 618: 577: 573: 569: 568: 170:Legal status 164:Legal status 98:License data 3309:Zafirlukast 3279:Thiothixene 3259:Terconazole 3209:Simvastatin 3084:Nisoldipine 3079:Nilvadipine 3064:Nicardipine 3034:Metacycline 2861:Dimercaprol 2816:Demecolcine 2776:Clindamycin 2771:Ciglitazone 2721:Artemisinin 2701:Ambrisentan 2605:Nigramide J 2540:Telmisartan 2500:Nicardipine 2410:Benfuracarb 2405:Artemisinin 2310:from market 2228:Dexrazoxane 2195:Deferiprone 2190:Deferasirox 2089:from market 2061:Ipecacuanha 1976:Dimercaprol 1932:Glutathione 1806:Dimercaprol 1705:Circulatory 1680:Reversal of 1618:Pralidoxime 1578:Nerve agent 1540:Cyprodenate 1505:Barbiturate 1162:(1): 7–14. 1012:10665/44053 709:snake venom 707:-dependent 570:Dimercaprol 476: g·mol 422:100.000.394 212:Identifiers 117:Dimercaprol 63:Other names 54:Trade names 21:Dimercaprol 3384:Categories 3289:Tianeptine 3254:Tenylidone 3249:Tacrolimus 3194:Rimexolone 3184:Rifampicin 3124:Plicamycin 3109:Paclitaxel 3094:Omeprazole 3074:Nifedipine 3049:Mevastatin 3044:Metyrapone 3024:Lovastatin 3019:Loratadine 2976:Hyperforin 2966:Haloprogin 2931:Felodipine 2906:Enzacamene 2886:Dronabinol 2851:Diclazuril 2830:prasterone 2786:Chloroxine 2761:Cephradine 2731:Bile acids 2545:Tolnaftate 2510:Permethrin 2495:Nevirapine 2490:Nefazodone 2459:prasterone 2420:Carvedilol 2400:Amiodarone 2371:modulators 2002:iodine-131 1937:Methionine 1907:Fomepizole 1691:Sugammadex 1671:Naltrexone 1661:Nalorphine 1545:Flumazenil 1490:Metadoxine 983:8 December 881:References 582:medication 481:3D model ( 469:Molar mass 372:ChEMBL1597 332:0CPP32S55X 303:ChemSpider 238:CAS Number 221:IUPAC name 58:BAL in Oil 3395:Antidotes 3214:Sirolimus 3204:Ritonavir 3199:Riodipine 3189:Rifaximin 3174:Reserpine 3159:Proadifen 3104:Oxatomide 3059:Nafcillin 3029:Meclizine 2891:Droxidopa 2871:Docetaxel 2796:Colforsin 2746:Bumecaine 2736:Bithionol 2648:Agonists: 2625:T-0901317 2600:Meclizine 2530:Reserpine 2520:Phenytoin 2505:Octicizer 2465:Efavirenz 2392:Agonists: 2320:Phase III 2308:Withdrawn 2157:, others) 2099:Phase III 2087:Withdrawn 1893:poisoning 1776:Protamine 1656:Nalmefene 1625:see also: 1613:Obidoxime 1598:Biperiden 1585:poisoning 1568:SCH-50911 1520:Ethamivan 1515:Bemegride 1458:Antidotes 860:DMSA scan 802:tellurium 701:snakebite 688:in which 633:pregnancy 203:Excretion 128:Routes of 90:Monograph 84:Drugs.com 3374:Medicine 3341:See also 3229:SR-12813 3119:Piperine 3099:Orlistat 3069:Nicotine 2941:Fentanyl 2926:Febantel 2901:Ecopipam 2866:Dinaline 2751:Cafestol 2741:Bosentan 2615:PK-11195 2240:Thallium 1981:Edetates 1966:thallium 1886:Methanol 1811:Succimer 1770:against 1759:against 1724:Glucagon 1666:Naloxone 1651:Doxapram 1603:Diazepam 1593:Atropine 1532:overdose 1507:overdose 1495:Thiamine 1390:21006485 1347:Archived 1325:44772701 1233:32376771 1184:26059921 1176:15698506 1141:20717537 1075:(2019). 1056:Archived 977:Archived 844:See also 830:lewisite 826:antidote 814:compound 798:selenium 782:chromium 770:antimony 716:in vitro 676:succimer 668:Lewisite 637:chelator 606:thallium 602:antimony 580:), is a 534:OCC(S)CS 283:DrugBank 140:ATC code 112:DailyMed 3329:Sesamin 3314:Zeranol 3244:Suramin 3014:LOE-908 2706:AMI-193 2620:S-07662 2535:TCPOBOP 2430:Chrysin 1961:mercury 1951:cadmium 1902:Ethanol 1840:nitrite 1772:heparin 1471:Nervous 1398:4129186 1370:Bibcode 1317:9292286 1297:Bibcode 1274:2692088 1224:7116364 1209:(542). 1132:2922724 836:-based 834:arsenic 808:History 778:cadmium 774:bismuth 766:mercury 762:in vivo 736:chelate 728:Arsenic 590:mercury 586:arsenic 504:Density 439:Formula 292:DB06782 258:PubChem 247:59-52-9 156:) 150: ( 148:V03AB09 114::  3405:Thiols 3360:Portal 2836:DHEA-S 2676:AA-861 2303:WHO-EM 2164:Copper 2082:WHO-EM 2048:Emetic 1707:system 1608:Oximes 1473:system 1396:  1388:  1362:Nature 1323:  1315:  1272:  1262:  1231:  1221:  1182:  1174:  1139:  1129:  1048:  1019:  939:  903:  794:nickel 792:, and 786:cobalt 690:copper 596:, and 527:SMILES 474:124.22 363:ChEMBL 352:D00167 185:℞-only 183: 110:  2435:CITCO 2269:BAPTA 2257:Other 2155:V03AC 1994:Other 1790:Other 1462:V03AB 1394:S2CID 1321:S2CID 1180:S2CID 732:thiol 694:liver 684:is a 625:fever 608:, or 547:InChI 483:JSmol 207:Urine 3007:and 2826:DHEA 2590:AITC 2455:DHEA 2289:EGTA 2284:DTPA 2279:DMSA 2274:DMPS 2223:EDTA 2210:Lead 2182:Iron 1956:lead 1386:PMID 1313:PMID 1270:PMID 1260:ISBN 1229:PMID 1172:PMID 1137:PMID 1046:ISBN 1017:ISBN 985:2016 937:ISBN 901:ISBN 865:EDTA 828:for 800:and 790:gold 753:and 598:lead 594:gold 343:KEGG 323:UNII 312:2971 272:3080 197:data 80:AHFS 2636:PXR 2380:CAR 2264:ALA 2218:BAL 1378:doi 1366:156 1305:doi 1252:doi 1219:PMC 1211:doi 1164:doi 1127:PMC 1117:doi 1081:hdl 1007:hdl 929:doi 578:BAL 388:EPA 262:CID 153:WHO 3386:: 2316:: 2149:/ 2095:: 1418:. 1392:. 1384:. 1376:. 1364:. 1345:. 1333:^ 1319:. 1311:. 1303:. 1293:16 1291:. 1268:. 1258:. 1227:. 1217:. 1207:12 1205:. 1201:. 1178:. 1170:. 1160:18 1158:. 1135:. 1125:. 1111:. 1107:. 1095:^ 1064:^ 1054:. 1040:. 1015:. 954:^ 945:. 935:. 840:. 788:, 784:, 780:, 776:, 772:, 768:, 757:. 719:. 705:Zn 678:. 654:. 616:. 604:, 592:, 588:, 179:US 107:US 3362:: 2842:) 2838:( 2832:) 2828:( 2461:) 2457:( 2360:e 2353:t 2346:v 2153:( 2139:e 2132:t 2125:v 1968:) 1949:( 1888:/ 1778:) 1774:( 1767:) 1763:( 1580:/ 1464:) 1460:( 1450:e 1443:t 1436:v 1400:. 1380:: 1372:: 1327:. 1307:: 1299:: 1276:. 1254:: 1235:. 1213:: 1186:. 1166:: 1143:. 1119:: 1113:7 1083:: 1025:. 1009:: 987:. 931:: 909:. 576:( 485:) 462:2 459:S 456:O 453:8 450:H 447:3 444:C 390:) 386:( 181:: 82:/

Index



Trade names
AHFS
Drugs.com
Monograph
License data
DailyMed
Dimercaprol
Routes of
administration

ATC code
V03AB09
WHO
Legal status
℞-only
Pharmacokinetic
Excretion
IUPAC name
CAS Number
59-52-9
PubChem
3080
DrugBank
DB06782
ChemSpider
2971
UNII
0CPP32S55X
KEGG
D00167

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