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Cytoscape

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Cytoscape was originally created at the Institute of Systems Biology in Seattle in 2002. Now, it is developed by an international consortium of open source developers. Cytoscape was initially made public in July, 2002 (v0.8); the second release (v0.9) was in November, 2002, and v1.0 was released in
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While Cytoscape is most commonly used for biological research applications, it is agnostic in terms of usage. Cytoscape can visualize and analyze network graphs of any kind involving nodes and edges (e.g., social networks). A vital aspect of the software architecture of Cytoscape is the use of
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March 2003. Version 1.1.1 is the last stable release for the 1.0 series. Version 2.0 was initially released in 2004; Cytoscape 2.83, the final 2.xx version, was released in May 2012. Version 3.0 was released Feb 1, 2013, and the latest version, 3.4.0, was released in May 2016.
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The Cytoscape core developer team continues to work on this project and released Cytoscape 3.0 in 2013. This represented a major change in the Cytoscape architecture; it is a more modularized, expandable and maintainable version of the software.
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Yeast Protein–protein/Protein–DNA interaction network visualized by Cytoscape. Node degree is mapped to node size
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plugins for specialized features. Plugins are developed by core developers and the greater user community.
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software architecture by anyone and plugin community development is encouraged. Cytoscape also has a
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that can be used to analyse and visualise graphs in JavaScript environments, like a browser.
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Matrix-assisted laser desorption ionization-time of flight mass spectrometer
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profiles and other state data. Additional features are available as
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Bell GW, Lewitter F (2006). "Visualizing Networks".
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Vol. 411. pp. 408–21. 363:DNA Microarrays, Part B: Databases and Statistics 946: 851: 458: 360: 865: 738:Matrix-assisted laser desorption ionization 858: 844: 806: 465: 451: 337: 223: 280: 947: 426:https://cytoscape.org/screenshots.html 268:Protein–protein interaction prediction 839: 780:European Molecular Biology Laboratory 446: 965:Mathematical and theoretical biology 13: 14: 991: 410: 901:Microsoft Automatic Graph Layout 818: 817: 805: 19: 758:Chromosome conformation capture 73:3.8.2 / 29 October 2020 395: 354: 305: 288:"Cytoscape 3.8.2 is released!" 210: 194:-centric sister project named 176:molecular interaction networks 1: 786:National Institutes of Health 371:10.1016/S0076-6879(06)11022-8 273: 37:Institute for Systems Biology 472: 7: 702:Structure-based drug design 438:Cytoscape omictools webpage 263:Metabolic network modelling 236: 10: 996: 201: 919: 871: 801: 792:Wellcome Sanger Institute 766: 715: 675: 563: 480: 402:Cytoscape Product Roadmap 140: 128: 116: 102: 92: 88: 66: 62: 54: 42: 30: 18: 748:Microfluidic-based tools 593:Human Connectome Project 525:Human Microbiome Project 219: 975:Cross-platform software 955:Bioinformatics software 866:Graph analysis software 733:Electrospray ionization 605:Human Epigenome Project 980:Java platform software 970:Graph drawing software 774:DNA Data Bank of Japan 690:Human proteome project 493:Computational genomics 243:Computational genomics 229: 753:Isotope affinity tags 707:Expression proteomics 227: 178:and integrating with 75:; 3 years ago 513:Human Genome Project 498:Comparative genomics 253:JavaScript framework 723:2-D electrophoresis 697:Call-map proteomics 555:Structural genomics 542:Population genomics 503:Functional genomics 25:Cytoscape home page 677:Structural biology 488:Cognitive genomics 330:10.1101/gr.1239303 258:JavaScript library 230: 32:Original author(s) 942: 941: 833: 832: 728:Mass spectrometer 537:Personal genomics 380:978-0-12-182816-5 292:groups.google.com 169:software platform 156: 155: 987: 860: 853: 846: 837: 836: 821: 820: 809: 808: 652:Pharmacogenomics 647:Pharmacogenetics 467: 460: 453: 444: 443: 422: 421: 419:Official website 404: 399: 393: 392: 358: 352: 351: 341: 324:(11): 2498–504. 309: 303: 302: 300: 298: 284: 152: 149: 147: 123:Image processing 104:Operating system 83: 81: 76: 23: 16: 15: 995: 994: 990: 989: 988: 986: 985: 984: 960:Systems biology 945: 944: 943: 938: 915: 867: 864: 834: 829: 797: 762: 711: 671: 667:Transcriptomics 657:Systems biology 642:Paleopolyploidy 578:Cheminformatics 559: 476: 471: 417: 416: 413: 408: 407: 400: 396: 381: 359: 355: 310: 306: 296: 294: 286: 285: 281: 276: 239: 222: 213: 204: 180:gene expression 144: 84: 79: 77: 74: 55:Initial release 26: 12: 11: 5: 993: 983: 982: 977: 972: 967: 962: 957: 940: 939: 937: 936: 931: 925: 923: 917: 916: 914: 913: 908: 903: 898: 893: 888: 883: 877: 875: 869: 868: 863: 862: 855: 848: 840: 831: 830: 828: 827: 815: 802: 799: 798: 796: 795: 789: 783: 777: 770: 768: 764: 763: 761: 760: 755: 750: 745: 740: 735: 730: 725: 719: 717: 716:Research tools 713: 712: 710: 709: 704: 699: 694: 693: 692: 681: 679: 673: 672: 670: 669: 664: 662:Toxicogenomics 659: 654: 649: 644: 639: 634: 629: 624: 619: 614: 609: 608: 607: 597: 596: 595: 585: 580: 575: 569: 567: 565:Bioinformatics 561: 560: 558: 557: 552: 544: 539: 534: 529: 528: 527: 517: 516: 515: 508:Genome project 505: 500: 495: 490: 484: 482: 478: 477: 470: 469: 462: 455: 447: 441: 440: 435: 433:Cytoscape wiki 430: 429: 428: 412: 411:External links 409: 406: 405: 394: 379: 353: 304: 278: 277: 275: 272: 271: 270: 265: 260: 255: 250: 245: 238: 235: 221: 218: 212: 209: 203: 200: 166:bioinformatics 154: 153: 142: 138: 137: 132: 126: 125: 120: 114: 113: 106: 100: 99: 94: 90: 89: 86: 85: 72: 70: 68:Stable release 64: 63: 60: 59: 56: 52: 51: 49:Cytoscape Team 46: 40: 39: 34: 28: 27: 24: 9: 6: 4: 3: 2: 992: 981: 978: 976: 973: 971: 968: 966: 963: 961: 958: 956: 953: 952: 950: 935: 932: 930: 927: 926: 924: 922: 918: 912: 909: 907: 904: 902: 899: 897: 894: 892: 889: 887: 884: 882: 879: 878: 876: 874: 870: 861: 856: 854: 849: 847: 842: 841: 838: 826: 825: 816: 814: 813: 804: 803: 800: 793: 790: 787: 784: 781: 778: 775: 772: 771: 769: 767:Organizations 765: 759: 756: 754: 751: 749: 746: 744: 741: 739: 736: 734: 731: 729: 726: 724: 721: 720: 718: 714: 708: 705: 703: 700: 698: 695: 691: 688: 687: 686: 683: 682: 680: 678: 674: 668: 665: 663: 660: 658: 655: 653: 650: 648: 645: 643: 640: 638: 637:Nutrigenomics 635: 633: 630: 628: 625: 623: 620: 618: 615: 613: 610: 606: 603: 602: 601: 598: 594: 591: 590: 589: 586: 584: 583:Chemogenomics 581: 579: 576: 574: 571: 570: 568: 566: 562: 556: 553: 551: 549: 545: 543: 540: 538: 535: 533: 530: 526: 523: 522: 521: 518: 514: 511: 510: 509: 506: 504: 501: 499: 496: 494: 491: 489: 486: 485: 483: 479: 475: 468: 463: 461: 456: 454: 449: 448: 445: 439: 436: 434: 431: 427: 424: 423: 420: 415: 414: 403: 398: 390: 386: 382: 376: 372: 368: 364: 357: 349: 345: 340: 335: 331: 327: 323: 319: 315: 308: 293: 289: 283: 279: 269: 266: 264: 261: 259: 256: 254: 251: 249: 248:Graph drawing 246: 244: 241: 240: 234: 226: 217: 208: 199: 197: 193: 189: 185: 181: 177: 174: 170: 167: 164: 160: 151: 143: 139: 136: 133: 131: 127: 124: 121: 119: 115: 111: 107: 105: 101: 98: 95: 91: 87: 71: 69: 65: 61: 57: 53: 50: 47: 45: 41: 38: 35: 33: 29: 22: 17: 880: 822: 810: 632:Microbiomics 627:Metabolomics 588:Connectomics 547: 520:Metagenomics 397: 362: 356: 321: 317: 307: 295:. Retrieved 291: 282: 231: 214: 205: 196:Cytoscape.js 158: 157: 44:Developer(s) 934:Mathematica 921:Proprietary 600:Epigenomics 532:Pangenomics 211:Development 173:visualizing 163:open source 949:Categories 685:Proteomics 622:Lipidomics 617:Immunomics 318:Genome Res 274:References 192:JavaScript 148:.cytoscape 93:Written in 80:2020-10-29 881:Cytoscape 612:Glycomics 159:Cytoscape 58:July 2002 906:NetworkX 886:Graphviz 824:Category 550:genomics 474:Genomics 389:16939803 348:14597658 297:11 March 237:See also 573:Biochip 202:History 184:plugins 141:Website 130:License 112:-based) 78: ( 896:igraph 481:Fields 387:  377:  346:  339:403769 336:  161:is an 929:Maple 911:Tulip 891:Gephi 788:(USA) 548:Socio 220:Usage 108:Any ( 873:Free 812:List 794:(UK) 782:(EU) 776:(JP) 385:PMID 375:ISBN 344:PMID 299:2021 188:Java 171:for 150:.org 135:LGPL 118:Type 110:Java 97:Java 367:doi 334:PMC 326:doi 146:www 951:: 383:. 373:. 342:. 332:. 322:13 320:. 316:. 290:. 859:e 852:t 845:v 466:e 459:t 452:v 391:. 369:: 350:. 328:: 301:. 82:)

Index


Original author(s)
Institute for Systems Biology
Developer(s)
Cytoscape Team
Stable release
Java
Operating system
Java
Type
Image processing
License
LGPL
www.cytoscape.org
open source
bioinformatics
software platform
visualizing
molecular interaction networks
gene expression
plugins
Java
JavaScript
Cytoscape.js

Computational genomics
Graph drawing
JavaScript framework
JavaScript library
Metabolic network modelling

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