20:
1252:
1751:
1763:
138:
to receptors on T cells. The most important of these APCs are highly specialized dendritic cells; conceivably operating solely to ingest and present antigens. Activated effector T cells can be placed into three functioning classes, detecting
796:. Recently, there have been a large amount of NKp46 cells that express certain master s that allow them to be designated as a distinct lineage of natural killer cells termed ILC1s. ILC1s are characterized by the ability to produce
469:
Common innate lymphoid progenitors may then be differentiated into a natural killer progenitor (NKp) or a common helper like innate lymphoid progenitor (CHILp). NKp cells may then be induced to differentiate into
1163:
27:(outer three) surrounding a cancer cell. Lytic granules (red) are secreted at the contact site, killing the target. Cytotoxic T cells are powerful agents of cellular immunity.
1736:
2831:
1801:
1181:
2390:
3310:
2824:
462:(CLp) which then differentiates to become the common innate lymphoid progenitor (CILp) and the t-cell progenitor (Tp) through the process of
1794:
2308:
1921:
2817:
692:
1 cells are also characterized by the expression of chemokine receptors which allow their movement to sites of inflammation. The main
3393:
3388:
2989:
1241:
697:
505:
T-cell progenitors may differentiate into naĂŻve CD8 cells or naĂŻve CD4 cells. NaĂŻve CD8 cells may then further differentiate into T
3344:
2383:
1787:
1208:
973:
3166:
1417:
581:
1, and group 1 ILCS activate macrophages, converting them to potent effector cells. It provides defense against intracellular
479:
434:
2376:
1002:
3383:
3161:
3020:
2722:
131:
3202:
3064:
1726:
1448:
3156:
2717:
1767:
1731:
3059:
3282:
2660:
1575:
1342:
267:
that influence the function of other cells involved in adaptive immune responses and innate immune responses.
3470:
3339:
2191:
1999:
1041:
1039:
1037:
1035:
1033:
1031:
1029:
1027:
1025:
1023:
673:
3241:
3044:
1565:
1201:
1087:
1085:
1083:
1020:
194:
and cell-mediated components. Some cell-mediated components of the innate immune system include myeloid
3272:
2950:
2546:
1422:
610:
459:
203:
3465:
3302:
3125:
1236:
1080:
2368:
3216:
2985:
2971:
2253:
1592:
1271:
1231:
115:
3480:
3089:
2852:
2726:
2484:
2355:
2274:
2143:
1488:
1266:
280:
1176:
3460:
2466:
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1755:
1660:
1645:
1473:
1367:
1347:
1194:
235:
187:
3455:
2695:
2551:
2529:
1146:
71:
3445:
3440:
3378:
3373:
3357:
3267:
3197:
3054:
2966:
2809:
2712:
2645:
2556:
2480:
2350:
1685:
1548:
1412:
1362:
785:
681:
602:
427:
296:
183:
164:
156:
78:, for which the protective function of immunization could be found in the humor (cell-free
3085:
565:
Type 1 immunity makes use of the type 1 subset for each of these cell types. By secreting
8:
3450:
3430:
2772:
2707:
2690:
2524:
2442:
2138:
2113:
1570:
1553:
1533:
1513:
793:
693:
471:
253:
3400:
857:
Ross
Russell, Amy L; Dryden, Matthew S; Pinto, Ashwin A; Lovett, Joanna K (2018-10-03).
260:
of cytotoxic granules (for natural killer cells) and phagocytosis (for macrophages); and
19:
3485:
3475:
3405:
3287:
3277:
3171:
3097:
3069:
3049:
2886:
2844:
2592:
2284:
1580:
1326:
1120:
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951:
938:
913:
894:
832:
606:
3107:
3102:
2902:
2891:
2640:
2406:
2148:
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1700:
1655:
1478:
1352:
1125:
1069:
943:
886:
878:
858:
661:
351:
148:
955:
898:
874:
3435:
3151:
3002:
2997:
2938:
2865:
2840:
2760:
2700:
2672:
2667:
2635:
2622:
2612:
2225:
2128:
1943:
1635:
1602:
1357:
1115:
1105:
1059:
933:
925:
870:
826:
797:
753:
733:
729:
705:
657:
632:
566:
393:
378:
347:
319:
219:
191:
75:
51:
24:
613:
all being implicated in type 1 immunity. Type 1 immunity consists of these cells:
3292:
3262:
3146:
3074:
2928:
2881:
2655:
2174:
1963:
1895:
1779:
1468:
1463:
1453:
737:
123:
39:
1164:
functions%20in%20steady-state%20homeostasis%20and%20during%20immune%20challenge.
318:, turning them into potent effector cells. This is achieved by the secretion of
279:
and microbes that infect non-phagocytic cells. It is most effective in removing
3176:
3130:
2923:
2682:
2627:
2568:
2488:
2461:
2240:
2220:
2169:
2013:
1958:
1938:
1933:
1855:
1819:
1640:
1617:
1523:
1518:
1458:
1443:
1407:
1292:
1152:
1064:
1047:
757:
669:
554:
534:
522:
510:
483:
475:
386:
370:
90:, for which the protective function of immunization was associated with cells.
1110:
3424:
3351:
2943:
2650:
2539:
2320:
2230:
1875:
1538:
1493:
1402:
1217:
1182:
Cell-mediated immunity: How T cells recognize and respond to foreign antigens
882:
821:
809:
709:
550:
542:
518:
499:
491:
463:
366:
362:
335:
103:
95:
1158:
3246:
3036:
2918:
2907:
2617:
2602:
2597:
2534:
2432:
2345:
2279:
2248:
2108:
1973:
1865:
1828:
1811:
1690:
1675:
1587:
1528:
1427:
1397:
1306:
1129:
1073:
947:
890:
598:
594:
83:
79:
1048:"The 3 major types of innate and adaptive cell-mediated effector immunity"
812:
in response to cytokine stimulation but have low or no cytotoxic ability.
768:
activation is required for both interferon gamma and cytolytic potential.
2933:
2913:
2897:
2022:
1905:
1680:
1670:
1665:
315:
218:
T-cell mediated immunity or T-cell immunity: activating antigen-specific
119:
1251:
1160:
The 3 major types of innate and adaptive cell-mediated effector immunity
1094:"Innate lymphocytes—lineage, localization and timing of differentiation"
2740:
2493:
2399:
2133:
2123:
2103:
2095:
2057:
2040:
2030:
1968:
1860:
1607:
1560:
1483:
1392:
276:
249:
176:
1166:
Innate lymphocytes-lineage, localization and timing of differentiation
929:
2798:
2503:
2398:
2340:
2186:
2118:
2069:
2035:
1900:
1880:
1870:
288:
257:
223:
195:
152:
99:
55:
47:
1155:
Immunobiology: The Immune System in Health and
Disease. 5th edition.
2788:
2573:
2561:
2519:
2473:
2437:
2313:
2207:
2086:
2074:
2050:
2045:
1833:
1710:
1612:
586:
582:
311:
307:
272:
264:
227:
144:
74:
medicine system, the immune system was imagined into two branches:
43:
385:
17) were also discovered which are named after their secretion of
256:
action: enabling the destruction of pathogens via recognition and
2856:
2793:
2607:
2456:
2427:
2215:
2062:
1650:
1543:
1321:
1316:
590:
303:
199:
172:
140:
135:
127:
107:
59:
1186:
736:
secreted by these cells seems to be important in downregulating
3225:
2765:
2753:
2498:
2449:
2303:
2179:
1843:
1695:
1287:
805:
725:
721:
653:
292:
239:
111:
3192:
2860:
2258:
1737:
List of largest biomedical companies by market capitalization
1597:
856:
789:
773:
765:
717:
677:
284:
243:
231:
2839:
1045:
295:, and intracellular bacteria. It also plays a major role in
1311:
769:
701:
649:
495:
487:
446:
440:
163:, which primarily function to activate macrophages, and 3)
106:, which are immature T cells that have yet to encounter an
716:
1 cells to sites of infection by releasing the chemokines
1301:
1297:
801:
570:
323:
91:
1046:
Annunziato, F; Romagnani, C; Romagnani, S (March 2015).
911:
130:
in some circumstances, load antigenic peptides onto the
46:. Rather, cell-mediated immunity is the activation of
1827:
635:
producing group 1 ILCs(ILC1 and
Natural killer cells)
430:, they may be classified into three main categories
478:. CHILp cells may be induced to differentiate into
1809:
529:17 cells. NaĂŻve CD4 cells may differentiate into T
458:All type 1 cells begin their development from the
656:that the signature cytokines for these cells are
3422:
3311:Transfusion-associated graft-versus-host disease
912:Romo, MR; PĂ©rez-MartĂnez, D; Ferrer, CC (2016).
776:are the main chemokine receptors for this cell.
513:exposure, can induce the differentiation into T
338:may be differentiated into two main categories:
271:Cell-mediated immunity is directed primarily at
16:Immune response that does not involve antibodies
1052:The Journal of Allergy and Clinical Immunology
664:. The main cytokine for differentiation into T
2825:
2384:
1795:
1202:
914:"Innate immunity in vertebrates: an overview"
283:, but also participates in defending against
230:of foreign antigen on their surface, such as
214:Cellular immunity protects the body through:
1092:Kansler, Emily R.; Li, Ming O. (July 2019).
792:and were originally thought to only include
423:17 were discovered that also secrete IL-17.
143:antigens originating from various types of
2832:
2818:
2391:
2377:
1802:
1788:
1209:
1195:
967:
965:
263:Stimulating cells to secrete a variety of
134:(MHC) of the cell, in turn presenting the
1119:
1109:
1091:
1063:
996:
994:
937:
302:Type 1 immunity is directed primarily at
1242:Competitions and prizes in biotechnology
859:"Lyme disease: diagnosis and management"
171:, which primarily function to stimulate
110:, are converted into activated effector
42:that does not rely on the production of
18:
3345:Allergic bronchopulmonary aspergillosis
2309:Megakaryocyte–erythroid progenitor cell
962:
453:
23:Immunofluorescence micrograph of three
3423:
991:
852:
850:
848:
668:1 cells is IL-12 which is produced by
151:, which kill infected target cells by
3167:Post-streptococcal glomerulonephritis
2813:
2372:
1783:
1190:
784:Groups 1 ILCs are defined to include
525:can induce the differentiation into T
98:provide protection against different
1762:
971:
788:expressing the transcription factor
1153:Chapter 8:T Cell-Mediated Immunity
1098:Cellular & Molecular Immunology
1000:
845:
13:
1170:
560:
314:and is responsible for activating
14:
3497:
3384:Autoimmune polyendocrine syndrome
1216:
672:in response to the activation of
3021:Hemolytic disease of the newborn
1761:
1750:
1749:
1250:
760:promote differentiation toward T
449:which secrete type 17 cytokines.
419:cells, a third category called T
132:major histocompatibility complex
3203:Subacute bacterial endocarditis
3065:Immune thrombocytopenic purpura
1727:Index of biotechnology articles
1140:
875:10.1136/practneurol-2018-001998
443:which secrete type 2 cytokines,
437:which secrete type 1 cytokines,
2718:Immunoglobulin class switching
1732:List of biotechnology articles
1177:Cell-Mediated Immunity. Murphy
1007:British Society for Immunology
978:British Society for Immunology
905:
752:These cells generally produce
1:
3283:Postorgasmic illness syndrome
1576:Genetically modified organism
1343:Biotechnology industrial park
838:
674:pattern recognition receptors
593:. It is also responsible for
54:, and the release of various
3340:Hypersensitivity pneumonitis
2000:Extramedullary hematopoiesis
829:(vs. cell-mediated immunity)
396:may also be categorized as:
234:-infected cells, cells with
155:without using cytokines, 2)
118:(APCs). These APCs, such as
7:
3406:Systemic autoimmune disease
3242:Allergic contact dermatitis
3162:Hypersensitivity vasculitis
3045:Autoimmune hemolytic anemia
1566:Environmental biotechnology
815:
740:in the epithelial barrier.
329:
209:
204:intraepithelial lymphocytes
147:: The first class being 1)
10:
3502:
2912:common allergies include:
2547:Polyclonal B cell response
1065:10.1016/j.jaci.2014.11.001
648:It has been found in both
611:inflammatory bowel disease
460:common lymphoid progenitor
65:
3366:
3332:
3323:
3301:
3255:
3234:
3215:
3185:
3139:
3124:
3083:
3035:
3028:
3014:
2984:
2959:
2874:
2851:
2781:
2739:
2681:
2582:
2512:
2420:
2413:
2333:
2293:
2267:
2239:
2206:
2166:Antigen-presenting cells
2159:
2094:
2085:
2021:
2012:
1992:
1954:
1929:
1920:
1891:
1851:
1842:
1818:
1745:
1719:
1626:
1506:
1436:
1385:
1376:
1335:
1280:
1259:
1248:
1237:Timeline of biotechnology
1224:
1149:(Encyclopædia Britannica)
1111:10.1038/s41423-019-0211-7
226:in body cells displaying
198:, innate lymphoid cells (
182:In another ideology, the
70:In the late 19th century
3157:Henoch–Schönlein purpura
2972:Eosinophilic esophagitis
2254:Nucleated red blood cell
1810:Myeloid blood cells and
1593:Microbial biodegradation
1272:Industrial biotechnology
1232:History of biotechnology
624:CD8 cytotoxic T cells (T
377:A third category called
222:that are able to induce
116:antigen-presenting cells
3273:Hashimoto's thyroiditis
3060:Guillain–Barré syndrome
2356:Hematopoietic stem cell
2275:Leukocyte extravasation
2144:Foreign-body giant cell
1267:Colors of biotechnology
756:. Interferon gamma and
52:cytotoxic T-lymphocytes
3374:Autoimmune adrenalitis
2661:Tolerance in pregnancy
2403:adaptive immune system
1661:Biomedical engineering
1368:Pharmaceutical company
1348:Biotechnology products
1147:Cell-mediated immunity
974:"Natural Killer Cells"
601:with diseases such as
361:2 cells which produce
346:1 cells which produce
236:intracellular bacteria
188:adaptive immune system
36:cell-mediated immunity
28:
2696:Somatic hypermutation
2530:Polyclonal antibodies
2525:Monoclonal antibodies
712:are able to recruit T
72:Hippocratic tradition
22:
3379:Autoimmune hepatitis
3358:Transplant rejection
3268:Giant cell arteritis
3198:Rheumatoid arthritis
3055:Goodpasture syndrome
2967:Autoimmune urticaria
2713:Junctional diversity
2481:Antigen presentation
2351:Hematopoietic system
2139:Langhans giant cells
1686:Chemical engineering
1549:Reproductive cloning
1413:Hybridoma technology
1363:Human Genome Project
794:natural killer cells
682:transcription factor
603:rheumatoid arthritis
472:natural killer cells
454:Development of cells
297:transplant rejection
281:virus-infected cells
184:innate immune system
3471:Infectious diseases
2845:autoimmune diseases
2708:V(D)J recombination
2691:Affinity maturation
2443:Antigenic variation
2114:Alveolar macrophage
1571:Genetic engineering
1554:Therapeutic cloning
1534:Bionic architecture
1514:Animal cell culture
1281:Biological concepts
972:Eissmann, Philipp.
863:Practical Neurology
696:on these cells are
694:chemokine receptors
254:natural killer cell
190:each comprise both
114:after encountering
50:, antigen-specific
3288:Reactive arthritis
3278:Multiple sclerosis
3172:Reactive arthritis
3070:Pemphigus vulgaris
3050:Bullous pemphigoid
2951:Penicillin allergy
2887:Allergic urticaria
2285:Intrinsic immunity
2149:Touton giant cells
1627:Interdisciplinary
1581:Molecular genetics
1327:Selective breeding
607:multiple sclerosis
415:Similarly to CD4 T
58:in response to an
29:
3418:
3417:
3414:
3413:
3319:
3318:
3211:
3210:
3120:
3119:
3116:
3115:
3108:Pernicious anemia
3103:Myasthenia gravis
2980:
2979:
2903:Atopic dermatitis
2892:Allergic rhinitis
2807:
2806:
2735:
2734:
2485:professional APCs
2366:
2365:
2329:
2328:
2202:
2201:
2129:Epithelioid cells
2008:
2007:
1988:
1987:
1984:
1983:
1916:
1915:
1777:
1776:
1706:Nanobiotechnology
1701:Molecular biology
1502:
1501:
1353:Biotechnology law
930:10.1111/imm.12597
680:is a distinctive
662:lymphotoxin alpha
394:cytotoxic T-cells
379:T helper 17 cells
352:lymphotoxin alpha
242:cells displaying
220:cytotoxic T cells
149:Cytotoxic T cells
88:cellular immunity
32:Cellular immunity
25:cytotoxic T cells
3493:
3466:Lymphatic system
3401:Sjögren syndrome
3330:
3329:
3232:
3231:
3137:
3136:
3033:
3032:
3012:
3011:
2872:
2871:
2841:Hypersensitivity
2834:
2827:
2820:
2811:
2810:
2701:Clonal selection
2673:Immune privilege
2668:Immunodeficiency
2623:Cross-reactivity
2613:Hypersensitivity
2418:
2417:
2393:
2386:
2379:
2370:
2369:
2300:Precursor cells
2226:Promegakaryocyte
2092:
2091:
2019:
2018:
1944:Promegakaryocyte
1927:
1926:
1849:
1848:
1840:
1839:
1825:
1824:
1804:
1797:
1790:
1781:
1780:
1765:
1764:
1753:
1752:
1603:Pharmacogenomics
1383:
1382:
1377:Basic techniques
1358:Green Revolution
1336:General concepts
1254:
1211:
1204:
1197:
1188:
1187:
1134:
1133:
1123:
1113:
1089:
1078:
1077:
1067:
1043:
1018:
1017:
1015:
1013:
998:
989:
988:
986:
984:
969:
960:
959:
941:
909:
903:
902:
854:
827:Humoral immunity
798:interferon gamma
754:interferon gamma
734:interferon gamma
732:. Additionally,
730:interferon gamma
706:Epithelial cells
658:interferon gamma
633:interferon gamma
567:interferon gamma
348:interferon gamma
320:interferon gamma
275:that survive in
76:humoral immunity
34:, also known as
3501:
3500:
3496:
3495:
3494:
3492:
3491:
3490:
3421:
3420:
3419:
3410:
3362:
3325:
3315:
3297:
3293:Type 1 diabetes
3263:Coeliac disease
3251:
3223:
3207:
3181:
3147:Arthus reaction
3128:
3112:
3098:Graves' disease
3079:
3075:Rheumatic fever
3024:
2992:
2976:
2955:
2882:Allergic asthma
2863:
2847:
2838:
2808:
2803:
2777:
2731:
2677:
2656:Clonal deletion
2584:
2578:
2508:
2409:
2397:
2367:
2362:
2325:
2289:
2268:Immune response
2263:
2241:Red blood cells
2235:
2198:
2175:Langerhans cell
2170:Dendritic cells
2155:
2081:
2004:
1980:
1964:Proerythroblast
1950:
1912:
1896:Monocytopoiesis
1887:
1831:
1814:
1808:
1778:
1773:
1741:
1715:
1656:Biopharmacology
1628:
1622:
1498:
1469:Electrophoresis
1464:Kidney dialysis
1454:Crystallization
1432:
1378:
1372:
1331:
1276:
1255:
1246:
1220:
1215:
1173:
1171:Further reading
1143:
1138:
1137:
1090:
1081:
1044:
1021:
1011:
1009:
1001:Saldana, José.
999:
992:
982:
980:
970:
963:
910:
906:
855:
846:
841:
818:
763:
747:
738:tight junctions
728:in response to
715:
691:
687:
670:dendritic cells
667:
643:
627:
620:
580:
576:
563:
561:Type 1 immunity
548:
540:
532:
528:
516:
508:
456:
422:
418:
410:
403:
384:
360:
345:
332:
212:
175:into producing
168:
160:
124:dendritic cells
68:
40:immune response
17:
12:
11:
5:
3499:
3489:
3488:
3483:
3481:Cell signaling
3478:
3473:
3468:
3463:
3458:
3453:
3448:
3443:
3438:
3433:
3416:
3415:
3412:
3411:
3409:
3408:
3403:
3398:
3397:
3396:
3391:
3381:
3376:
3370:
3368:
3364:
3363:
3361:
3360:
3355:
3349:
3348:
3347:
3336:
3334:
3327:
3321:
3320:
3317:
3316:
3314:
3313:
3307:
3305:
3299:
3298:
3296:
3295:
3290:
3285:
3280:
3275:
3270:
3265:
3259:
3257:
3253:
3252:
3250:
3249:
3244:
3238:
3236:
3229:
3213:
3212:
3209:
3208:
3206:
3205:
3200:
3195:
3189:
3187:
3183:
3182:
3180:
3179:
3177:Serum sickness
3174:
3169:
3164:
3159:
3154:
3149:
3143:
3141:
3134:
3131:Immune complex
3122:
3121:
3118:
3117:
3114:
3113:
3111:
3110:
3105:
3100:
3094:
3092:
3081:
3080:
3078:
3077:
3072:
3067:
3062:
3057:
3052:
3047:
3041:
3039:
3030:
3026:
3025:
3023:
3018:
3016:
3009:
3008:
3007:
3006:
3005:
3000:
2982:
2981:
2978:
2977:
2975:
2974:
2969:
2963:
2961:
2957:
2956:
2954:
2953:
2948:
2947:
2946:
2941:
2936:
2931:
2926:
2921:
2916:
2905:
2900:
2895:
2889:
2884:
2878:
2876:
2869:
2849:
2848:
2837:
2836:
2829:
2822:
2814:
2805:
2804:
2802:
2801:
2796:
2791:
2785:
2783:
2779:
2778:
2776:
2775:
2770:
2769:
2768:
2758:
2757:
2756:
2745:
2743:
2737:
2736:
2733:
2732:
2730:
2729:
2720:
2715:
2710:
2705:
2704:
2703:
2698:
2687:
2685:
2683:Immunogenetics
2679:
2678:
2676:
2675:
2670:
2665:
2664:
2663:
2658:
2653:
2648:
2643:
2631:
2630:
2628:Co-stimulation
2625:
2620:
2615:
2610:
2605:
2600:
2595:
2588:
2586:
2580:
2579:
2577:
2576:
2571:
2569:Immune complex
2565:
2564:
2559:
2554:
2549:
2544:
2543:
2542:
2537:
2532:
2527:
2516:
2514:
2510:
2509:
2507:
2506:
2501:
2496:
2491:
2489:Dendritic cell
2477:
2476:
2471:
2470:
2469:
2467:Conformational
2464:
2453:
2452:
2447:
2446:
2445:
2440:
2435:
2424:
2422:
2415:
2411:
2410:
2396:
2395:
2388:
2381:
2373:
2364:
2363:
2361:
2360:
2359:
2358:
2348:
2343:
2337:
2335:
2331:
2330:
2327:
2326:
2324:
2323:
2318:
2317:
2316:
2311:
2306:
2297:
2295:
2291:
2290:
2288:
2287:
2282:
2277:
2271:
2269:
2265:
2264:
2262:
2261:
2256:
2251:
2245:
2243:
2237:
2236:
2234:
2233:
2228:
2223:
2221:Megakaryoblast
2218:
2212:
2210:
2204:
2203:
2200:
2199:
2197:
2196:
2195:
2194:
2184:
2183:
2182:
2177:
2172:
2163:
2161:
2157:
2156:
2154:
2153:
2152:
2151:
2146:
2141:
2131:
2126:
2121:
2116:
2111:
2106:
2100:
2098:
2089:
2083:
2082:
2080:
2079:
2078:
2077:
2067:
2066:
2065:
2055:
2054:
2053:
2043:
2038:
2033:
2027:
2025:
2016:
2014:Myeloid tissue
2010:
2009:
2006:
2005:
2003:
2002:
1996:
1994:
1990:
1989:
1986:
1985:
1982:
1981:
1979:
1978:
1977:
1976:
1971:
1966:
1959:Erythropoiesis
1955:
1952:
1951:
1949:
1948:
1947:
1946:
1941:
1939:Megakaryoblast
1934:Thrombopoiesis
1930:
1924:
1918:
1917:
1914:
1913:
1911:
1910:
1909:
1908:
1903:
1892:
1889:
1888:
1886:
1885:
1884:
1883:
1878:
1873:
1868:
1863:
1856:Granulopoiesis
1852:
1846:
1837:
1822:
1816:
1815:
1807:
1806:
1799:
1792:
1784:
1775:
1774:
1772:
1771:
1759:
1746:
1743:
1742:
1740:
1739:
1734:
1729:
1723:
1721:
1717:
1716:
1714:
1713:
1708:
1703:
1698:
1693:
1688:
1683:
1678:
1673:
1668:
1663:
1658:
1653:
1648:
1646:Bioengineering
1643:
1641:Bioelectronics
1638:
1632:
1630:
1624:
1623:
1621:
1620:
1618:Tissue culture
1615:
1610:
1605:
1600:
1595:
1590:
1585:
1584:
1583:
1578:
1568:
1563:
1558:
1557:
1556:
1551:
1541:
1536:
1531:
1526:
1524:Bioinformatics
1521:
1519:Biofabrication
1516:
1510:
1508:
1504:
1503:
1500:
1499:
1497:
1496:
1491:
1486:
1481:
1476:
1471:
1466:
1461:
1459:Chromatography
1456:
1451:
1446:
1444:Centrifugation
1440:
1438:
1437:Chemical field
1434:
1433:
1431:
1430:
1425:
1420:
1415:
1410:
1408:Flow cytometry
1405:
1400:
1395:
1389:
1387:
1380:
1374:
1373:
1371:
1370:
1365:
1360:
1355:
1350:
1345:
1339:
1337:
1333:
1332:
1330:
1329:
1324:
1319:
1314:
1309:
1304:
1295:
1290:
1284:
1282:
1278:
1277:
1275:
1274:
1269:
1263:
1261:
1257:
1256:
1249:
1247:
1245:
1244:
1239:
1234:
1228:
1226:
1222:
1221:
1214:
1213:
1206:
1199:
1191:
1185:
1184:
1179:
1172:
1169:
1168:
1167:
1161:
1156:
1150:
1142:
1139:
1136:
1135:
1104:(7): 627–633.
1079:
1019:
990:
961:
924:(2): 125–139.
904:
869:(6): 455–464.
843:
842:
840:
837:
836:
835:
830:
824:
817:
814:
761:
745:
713:
689:
685:
665:
641:
637:
636:
629:
625:
622:
618:
578:
574:
562:
559:
546:
538:
530:
526:
514:
506:
455:
452:
451:
450:
444:
438:
420:
416:
413:
412:
408:
405:
401:
387:Interleukin 17
382:
375:
374:
358:
355:
343:
336:T-helper cells
331:
328:
269:
268:
261:
247:
211:
208:
166:
158:
96:helper T cells
67:
64:
15:
9:
6:
4:
3:
2:
3498:
3487:
3484:
3482:
3479:
3477:
3474:
3472:
3469:
3467:
3464:
3462:
3461:Immune system
3459:
3457:
3454:
3452:
3449:
3447:
3444:
3442:
3439:
3437:
3434:
3432:
3429:
3428:
3426:
3407:
3404:
3402:
3399:
3395:
3392:
3390:
3387:
3386:
3385:
3382:
3380:
3377:
3375:
3372:
3371:
3369:
3365:
3359:
3356:
3353:
3352:Latex allergy
3350:
3346:
3343:
3342:
3341:
3338:
3337:
3335:
3331:
3328:
3322:
3312:
3309:
3308:
3306:
3304:
3300:
3294:
3291:
3289:
3286:
3284:
3281:
3279:
3276:
3274:
3271:
3269:
3266:
3264:
3261:
3260:
3258:
3254:
3248:
3245:
3243:
3240:
3239:
3237:
3233:
3230:
3227:
3222:
3221:cell-mediated
3218:
3214:
3204:
3201:
3199:
3196:
3194:
3191:
3190:
3188:
3184:
3178:
3175:
3173:
3170:
3168:
3165:
3163:
3160:
3158:
3155:
3153:
3152:Farmer's lung
3150:
3148:
3145:
3144:
3142:
3138:
3135:
3132:
3127:
3123:
3109:
3106:
3104:
3101:
3099:
3096:
3095:
3093:
3091:
3087:
3082:
3076:
3073:
3071:
3068:
3066:
3063:
3061:
3058:
3056:
3053:
3051:
3048:
3046:
3043:
3042:
3040:
3038:
3034:
3031:
3027:
3022:
3019:
3017:
3013:
3010:
3004:
3001:
2999:
2996:
2995:
2994:
2993:
2991:
2987:
2983:
2973:
2970:
2968:
2965:
2964:
2962:
2958:
2952:
2949:
2945:
2942:
2940:
2937:
2935:
2932:
2930:
2927:
2925:
2922:
2920:
2917:
2915:
2911:
2910:
2909:
2906:
2904:
2901:
2899:
2896:
2893:
2890:
2888:
2885:
2883:
2880:
2879:
2877:
2873:
2870:
2867:
2862:
2858:
2854:
2850:
2846:
2842:
2835:
2830:
2828:
2823:
2821:
2816:
2815:
2812:
2800:
2797:
2795:
2792:
2790:
2787:
2786:
2784:
2780:
2774:
2771:
2767:
2764:
2763:
2762:
2759:
2755:
2752:
2751:
2750:
2747:
2746:
2744:
2742:
2738:
2728:
2724:
2721:
2719:
2716:
2714:
2711:
2709:
2706:
2702:
2699:
2697:
2694:
2693:
2692:
2689:
2688:
2686:
2684:
2680:
2674:
2671:
2669:
2666:
2662:
2659:
2657:
2654:
2652:
2651:Clonal anergy
2649:
2647:
2644:
2642:
2639:
2638:
2637:
2633:
2632:
2629:
2626:
2624:
2621:
2619:
2616:
2614:
2611:
2609:
2606:
2604:
2601:
2599:
2596:
2594:
2590:
2589:
2587:
2581:
2575:
2572:
2570:
2567:
2566:
2563:
2560:
2558:
2555:
2553:
2550:
2548:
2545:
2541:
2540:Microantibody
2538:
2536:
2533:
2531:
2528:
2526:
2523:
2522:
2521:
2518:
2517:
2515:
2511:
2505:
2502:
2500:
2497:
2495:
2492:
2490:
2486:
2482:
2479:
2478:
2475:
2472:
2468:
2465:
2463:
2460:
2459:
2458:
2455:
2454:
2451:
2448:
2444:
2441:
2439:
2436:
2434:
2431:
2430:
2429:
2426:
2425:
2423:
2419:
2416:
2412:
2408:
2404:
2401:
2394:
2389:
2387:
2382:
2380:
2375:
2374:
2371:
2357:
2354:
2353:
2352:
2349:
2347:
2344:
2342:
2339:
2338:
2336:
2332:
2322:
2321:Myelomonocyte
2319:
2315:
2312:
2310:
2307:
2305:
2302:
2301:
2299:
2298:
2296:
2292:
2286:
2283:
2281:
2278:
2276:
2273:
2272:
2270:
2266:
2260:
2257:
2255:
2252:
2250:
2247:
2246:
2244:
2242:
2238:
2232:
2231:Megakaryocyte
2229:
2227:
2224:
2222:
2219:
2217:
2214:
2213:
2211:
2209:
2205:
2193:
2190:
2189:
2188:
2185:
2181:
2178:
2176:
2173:
2171:
2168:
2167:
2165:
2164:
2162:
2158:
2150:
2147:
2145:
2142:
2140:
2137:
2136:
2135:
2132:
2130:
2127:
2125:
2122:
2120:
2117:
2115:
2112:
2110:
2109:Kupffer cells
2107:
2105:
2102:
2101:
2099:
2097:
2093:
2090:
2088:
2084:
2076:
2073:
2072:
2071:
2068:
2064:
2061:
2060:
2059:
2056:
2052:
2049:
2048:
2047:
2044:
2042:
2039:
2037:
2034:
2032:
2029:
2028:
2026:
2024:
2020:
2017:
2015:
2011:
2001:
1998:
1997:
1995:
1991:
1975:
1972:
1970:
1967:
1965:
1962:
1961:
1960:
1957:
1956:
1953:
1945:
1942:
1940:
1937:
1936:
1935:
1932:
1931:
1928:
1925:
1923:
1919:
1907:
1904:
1902:
1899:
1898:
1897:
1894:
1893:
1890:
1882:
1879:
1877:
1876:Metamyelocyte
1874:
1872:
1869:
1867:
1864:
1862:
1859:
1858:
1857:
1854:
1853:
1850:
1847:
1845:
1841:
1838:
1835:
1830:
1826:
1823:
1821:
1820:Hematopoiesis
1817:
1813:
1805:
1800:
1798:
1793:
1791:
1786:
1785:
1782:
1770:
1769:
1760:
1758:
1757:
1748:
1747:
1744:
1738:
1735:
1733:
1730:
1728:
1725:
1724:
1722:
1718:
1712:
1709:
1707:
1704:
1702:
1699:
1697:
1694:
1692:
1689:
1687:
1684:
1682:
1679:
1677:
1674:
1672:
1669:
1667:
1664:
1662:
1659:
1657:
1654:
1652:
1649:
1647:
1644:
1642:
1639:
1637:
1634:
1633:
1631:
1625:
1619:
1616:
1614:
1611:
1609:
1606:
1604:
1601:
1599:
1596:
1594:
1591:
1589:
1586:
1582:
1579:
1577:
1574:
1573:
1572:
1569:
1567:
1564:
1562:
1559:
1555:
1552:
1550:
1547:
1546:
1545:
1542:
1540:
1539:Cell immunity
1537:
1535:
1532:
1530:
1527:
1525:
1522:
1520:
1517:
1515:
1512:
1511:
1509:
1505:
1495:
1494:Sedimentation
1492:
1490:
1487:
1485:
1482:
1480:
1477:
1475:
1472:
1470:
1467:
1465:
1462:
1460:
1457:
1455:
1452:
1450:
1447:
1445:
1442:
1441:
1439:
1435:
1429:
1426:
1424:
1421:
1419:
1416:
1414:
1411:
1409:
1406:
1404:
1403:Cultured meat
1401:
1399:
1396:
1394:
1391:
1390:
1388:
1386:Biology field
1384:
1381:
1375:
1369:
1366:
1364:
1361:
1359:
1356:
1354:
1351:
1349:
1346:
1344:
1341:
1340:
1338:
1334:
1328:
1325:
1323:
1320:
1318:
1315:
1313:
1310:
1308:
1305:
1303:
1299:
1296:
1294:
1291:
1289:
1286:
1285:
1283:
1279:
1273:
1270:
1268:
1265:
1264:
1262:
1258:
1253:
1243:
1240:
1238:
1235:
1233:
1230:
1229:
1227:
1223:
1219:
1218:Biotechnology
1212:
1207:
1205:
1200:
1198:
1193:
1192:
1189:
1183:
1180:
1178:
1175:
1174:
1165:
1162:
1159:
1157:
1154:
1151:
1148:
1145:
1144:
1131:
1127:
1122:
1117:
1112:
1107:
1103:
1099:
1095:
1088:
1086:
1084:
1075:
1071:
1066:
1061:
1058:(3): 626–35.
1057:
1053:
1049:
1042:
1040:
1038:
1036:
1034:
1032:
1030:
1028:
1026:
1024:
1008:
1004:
1003:"Macrophages"
997:
995:
979:
975:
968:
966:
957:
953:
949:
945:
940:
935:
931:
927:
923:
919:
915:
908:
900:
896:
892:
888:
884:
880:
876:
872:
868:
864:
860:
853:
851:
849:
844:
834:
831:
828:
825:
823:
822:Immune system
820:
819:
813:
811:
807:
803:
799:
795:
791:
787:
782:
781:
777:
775:
771:
767:
759:
755:
750:
749:
741:
739:
735:
731:
727:
723:
719:
711:
710:keratinocytes
707:
703:
699:
695:
683:
679:
675:
671:
663:
659:
655:
651:
646:
645:
634:
630:
623:
616:
615:
614:
612:
608:
604:
600:
596:
592:
588:
584:
572:
568:
558:
556:
552:
545:exposure or T
544:
536:
533:1 cells upon
524:
520:
512:
509:1 cells upon
503:
501:
497:
493:
489:
485:
481:
477:
473:
467:
465:
464:lymphopoiesis
461:
448:
445:
442:
439:
436:
433:
432:
431:
429:
424:
406:
399:
398:
397:
395:
390:
388:
380:
372:
368:
364:
356:
353:
349:
341:
340:
339:
337:
327:
325:
321:
317:
313:
309:
305:
300:
298:
294:
290:
286:
282:
278:
274:
266:
262:
259:
255:
251:
248:
245:
241:
237:
233:
229:
225:
221:
217:
216:
215:
207:
205:
201:
197:
193:
189:
185:
180:
178:
174:
170:
162:
154:
150:
146:
142:
137:
133:
129:
125:
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109:
105:
104:Naive T cells
101:
97:
93:
89:
85:
81:
77:
73:
63:
61:
57:
53:
49:
45:
41:
37:
33:
26:
21:
3456:Cell biology
3247:Mantoux test
3220:
2908:Food allergy
2748:
2618:Inflammation
2603:Alloimmunity
2598:Autoimmunity
2583:Immunity vs.
2535:Autoantibody
2433:Superantigen
2280:Phagocytosis
2249:Reticulocyte
2023:Granulocytes
1974:Reticulocyte
1866:Promyelocyte
1829:Myelopoiesis
1766:
1754:
1691:Microbiology
1676:Biochemicals
1588:Gene therapy
1529:Biosynthesis
1507:Applications
1428:Spectroscopy
1398:Cell culture
1307:Fermentation
1141:Bibliography
1101:
1097:
1055:
1051:
1010:. Retrieved
1006:
981:. Retrieved
977:
921:
917:
907:
866:
862:
783:
780:Group 1 ILCs
779:
778:
751:
743:
742:
647:
639:
638:
599:autoimmunity
595:inflammation
564:
517:2 cells and
504:
468:
457:
425:
414:
391:
376:
333:
301:
270:
213:
181:
87:
80:bodily fluid
69:
35:
31:
30:
3446:Macrophages
3441:Human cells
2898:Anaphylaxis
2894:(Hay fever)
2741:Lymphocytes
2400:Lymphocytic
2134:giant cells
2124:Osteoclasts
2104:Histiocytes
2096:Macrophages
1906:Promonocyte
1681:Biorobotics
1671:Biomimetics
1666:Biomedicine
537:exposure, T
426:As for the
316:macrophages
120:macrophages
3451:Phagocytes
3431:Immunology
3425:Categories
3367:Autoimmune
3256:Autoimmune
3186:Autoimmune
3029:Autoimmune
2960:Autoimmune
2782:Substances
2646:Peripheral
2634:Inaction:
2513:Antibodies
2494:Macrophage
2407:complement
2058:Eosinophil
2041:Neutrophil
2031:Myeloblast
1969:Normoblast
1861:Myeloblast
1636:Bioeconomy
1608:Stem cells
1561:Embryology
1484:Filtration
1474:Extraction
1393:Bioreactor
1012:8 November
983:8 November
918:Immunology
839:References
688:1 cells. T
557:exposure.
289:protozoans
277:phagocytes
250:Macrophage
196:phagocytes
177:antibodies
48:phagocytes
44:antibodies
3486:Cytokines
3476:Apoptosis
3037:Cytotoxic
2799:Cytolysin
2789:Cytokines
2636:Tolerance
2585:tolerance
2504:Immunogen
2341:Phagocyte
2208:Platelets
2187:Monoblast
2119:Microglia
2087:Monocytes
2070:Mast cell
2036:Band cell
1901:Monoblast
1881:Band cell
1871:Myelocyte
1479:Fed Batch
1379:and tools
883:1474-7758
764:1 cells.
502:as well.
498:cells by
490:cells by
482:cells by
265:cytokines
258:secretion
246:antigens;
224:apoptosis
153:apoptosis
100:pathogens
94:cells or
56:cytokines
3326:multiple
3324:Unknown/
3126:Type III
3090:receptor
2939:Tree nut
2749:Cellular
2593:Immunity
2591:Action:
2574:Paratope
2562:Idiotype
2552:Allotype
2520:Antibody
2474:Mimotope
2438:Allergen
2421:Antigens
2414:Lymphoid
2314:CFU-GEMM
2075:CFU-Mast
2051:CFU-Baso
2046:Basophil
1834:CFU-GEMM
1756:Category
1711:Virology
1613:Telomere
1260:Branches
1130:30804475
1074:25528359
956:35251844
948:26878338
899:52915054
891:30282764
833:Immunity
816:See also
587:protozoa
583:bacteria
549:17 upon
411:2 cells.
404:1 cells,
330:Overview
312:protozoa
308:bacteria
273:microbes
228:epitopes
210:Synopsis
200:NK cells
186:and the
145:pathogen
38:, is an
3436:T cells
3333:Foreign
3235:Foreign
3226:T cells
3217:Type IV
3140:Foreign
3015:Foreign
2986:Type II
2929:Seafood
2875:Foreign
2857:allergy
2794:Opsonin
2773:NK cell
2761:Humoral
2641:Central
2608:Allergy
2557:Isotype
2457:Epitope
2428:Antigen
2216:CFU-Meg
2063:CFU-Eos
1993:General
1768:Commons
1651:Biology
1544:Cloning
1322:Protein
1317:Plasmid
1225:History
1121:6804950
939:4863567
748:1 Cells
644:1 Cells
621:1 cells
591:viruses
541:2 upon
486:, into
304:viruses
293:cancers
192:humoral
173:B cells
169:2 cells
161:1 cells
141:peptide
136:peptide
128:B cells
112:T cells
108:antigen
66:History
60:antigen
3354:(I+IV)
3086:Type V
2924:Peanut
2853:Type I
2766:B cell
2754:T cell
2499:B cell
2462:Linear
2450:Hapten
2346:Plasma
2304:CFU-GM
2180:CFU-DL
1844:CFU-GM
1812:plasma
1696:Mining
1629:fields
1288:Allele
1128:
1118:
1072:
954:
946:
936:
897:
889:
881:
806:GM-CSF
726:CXCL11
722:CXCL10
698:CXCR3A
654:humans
631:T-Bet
617:CD4+ T
609:, and
589:, and
369:, and
310:, and
240:cancer
238:, and
202:) and
126:, and
86:) and
3193:Lupus
2944:Wheat
2861:atopy
2334:Other
2294:Other
2259:CFU-E
2160:Other
1720:Lists
1598:Omics
952:S2CID
895:S2CID
790:T-bet
774:CXCR3
766:T-bet
758:IL-12
744:CD8 T
718:CXCL9
678:T-bet
640:CD4 T
555:IL-23
535:IL-12
523:IL-23
511:IL-12
484:IL-15
476:IL-15
371:IL-13
285:fungi
244:tumor
232:virus
84:serum
3394:APS2
3389:APS1
3303:GVHD
2990:ADCC
2919:Milk
2843:and
2405:and
1449:CSTR
1418:HPLC
1312:Gene
1293:Cell
1126:PMID
1070:PMID
1014:2018
985:2018
944:PMID
887:PMID
879:ISSN
810:IL-2
808:and
786:ILCs
772:and
770:CCR5
724:and
708:and
702:CCR5
700:and
684:of T
660:and
652:and
650:mice
597:and
577:1, T
569:and
551:IL-1
543:IL-4
519:IL-1
500:IL-7
496:ILC3
492:IL-7
488:ILC2
480:ILC1
447:ILC3
441:ILC2
435:ILC1
428:ILCs
392:CD8
367:IL-5
363:IL-4
350:and
334:CD4
322:and
252:and
3003:IgM
2998:IgG
2934:Soy
2914:Egg
2866:IgE
2727:HLA
2723:MHC
2192:MPS
1922:MEP
1489:PFR
1423:NMR
1302:RNA
1298:DNA
1116:PMC
1106:doi
1060:doi
1056:135
934:PMC
926:doi
922:148
871:doi
802:TNF
573:, T
571:TNF
553:or
521:or
494:or
474:by
324:TNF
92:CD4
82:or
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