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63:, which suppresses growth hormone release. Thus, levels of somatomedins are controlled via negative feedback through the intermediates of somatostatin and growth hormone. Somatomedins are produced in many tissues and have
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act on target tissue. Somatomedins inhibit the release of growth hormones by acting directly on anterior pituitary and by stimulating the secretion of
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that promote cell growth and division in response to stimulation by growth hormone (GH), also known as
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In addition to their actions that stimulate growth, somatomedins also stimulate production of
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action. The liver is thought to be the predominant source of circulating somatomedins.
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Group of proteins responsible for both promotion and inhibition of cellular growth
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are a group of proteins produced predominantly not by the liver when
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152:"Functional structure of the somatomedin B domain of vitronectin"
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140:Berner Levy Physiology 6th edition|page=723|
295:Transforming growth factor beta superfamily
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216:at the U.S. National Library of Medicine
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404:Nephroblastoma overexpressed protein
453:Parathyroid hormone-related protein
389:CCN intercellular signaling protein
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300:Vascular endothelial growth factor
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399:Connective tissue growth factor
491:extracellular ligand disorders
468:Tolloid-like metalloproteinase
290:Platelet-derived growth factor
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71:actions in addition to their
524:. You can help Knowledge by
106:insulin-like growth factor 1
104:, which is another name for
87:insulin-like growth factor 2
85:, which is another name for
41:Somatomedins are a group of
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394:Cysteine-rich protein 61
374:Agouti signaling protein
280:Fibroblast growth factor
218:Medical Subject Headings
95:, which is derived from
275:Epidermal growth factor
38:from the hypothalamus.
379:Agouti-related protein
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473:Tumor necrosis factor
78:Three forms include:
23:Somatomedin C, Human.
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210:at Wikimedia Commons
168:10.1110/ps.072819107
285:Nerve growth factor
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384:Angiogenic protein
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162:(7): 1502–8.
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102:Somatomedin C
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83:Somatomedin A
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526:expanding it
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214:Somatomedins
208:Somatomedins
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61:somatostatin
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54:somatotropin
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47:somatotropin
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36:somatostatin
28:Somatomedins
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478:Wnt protein
463:Somatomedin
125:Somatomedin
97:vitronectin
565:Categories
458:Semaphorin
443:Interferon
416:Endothelin
131:Dictionary
113:References
489:see also
369:Adipokine
129:eMedicine
73:endocrine
69:paracrine
65:autocrine
411:Cytokine
186:17567740
43:proteins
259:ligands
177:2206693
108:(IGF-1)
89:(IGF-2)
49:(STH).
310:Ephrin
220:(MeSH)
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516:This
448:Kinin
362:Other
353:EFNB3
348:EFNB2
343:EFNB1
338:EFNA5
333:EFNA4
328:EFNA3
323:EFNA2
318:EFNA1
522:stub
431:EDN3
426:EDN2
421:EDN1
182:PMID
67:and
172:PMC
164:doi
127:at
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Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
