47:
1266:
1233:
1080:
1042:
943:
531:. Regeneron expected to produce 70,000–300,000 treatment doses or 420,000–1,300,000 prevention doses. "By funding this manufacturing effort, the federal government will own the doses expected to result from the demonstration project," the government said in its July 7 news release. Regeneron similarly said in its own news release that same day that "the government has committed to making doses from these lots available to the American people at no cost and would be responsible for their distribution," noting that this depended on the government granting
322:
38:
290:
273:
256:
239:
216:
566:(FDA)). On October 7, Trump posted a five-minute video to Twitter reasserting that this drug should be "free." That same day, Regeneron filed with the FDA for emergency use authorization. In the filing, it specified that it currently had 50,000 doses and that it expected to reach a total of 300,000 doses "within the next few months." The FDA granted approval for emergency use authorization in November 2020.
1873:
723:
Fully Human
Monoclonal Antibodies: Regeneron has developed a suite (VelociSuite) of patented technologies, including VelocImmune and VelociMab, that allow Regeneron scientists to determine the best targets for therapeutic intervention and rapidly generate high-quality, fully human antibodies drug
417:
In July 2015, the company announced a new global collaboration with Sanofi to discover, develop, and commercialize new immuno-oncology drugs, which could generate more than $ 2 billion for
Regeneron, with $ 640 million upfront, $ 750 million for proof-of-concept data, and $ 650 million from the
719:
Trap Fusion
Proteins: Regeneron's novel and patented Trap technology creates high-affinity product candidates for many types of signaling molecules, including growth factors and cytokines. The Trap technology involves fusing two distinct fully human receptor components and a fully human
1454:
1760:
1279:
1462:
590:
injection) was approved by the U.S. Food and Drug
Administration (FDA) in November 2011 to treat a common cause of blindness in the elderly. Eylea is reported to cost $ 11,000 per year for each eye treated.
453:
In May 2020, Regeneron announced it would repurchase approx. 19.2 million of its shares for around $ 5 billion, held directly by Sanofi. Prior to the transaction, Sanofi held 23.2 million
Regeneron shares.
1635:
2010:
1064:
870:
1026:
927:
1314:
1341:
1301:
433:(BARDA) that the U.S. government would fund 80% of the costs for Regeneron to develop and manufacture antibody-based medications, which subsequently, in 2020, included their
1775:"Regeneron and Sanofi Announce FDA Approval of Kevzara (sarilumab) for the Treatment of Moderately to Severely Active Rheumatoid Arthritis in Adult Patients (NASDAQ:REGN)"
1568:
2003:
458:
1175:
1485:
3387:
3377:
3372:
1372:
1890:
1828:
1106:
3397:
2019:
1996:
524:
430:
1761:"Regeneron and Sanofi Announce FDA Approval of Dupixent (dupilumab), the First Targeted Biologic Therapy for Adults with Moderate-to-Severe Atopic Dermatitis"
965:
3392:
3367:
497:
3362:
403:
blocker. VEGF is a protein that normally stimulates the growth of blood vessels, and interleukin-1 is a protein that is normally involved in inflammation.
2501:
2491:
2481:
2471:
2461:
2451:
2441:
2431:
2421:
1643:
1706:
1684:
1144:
410:
and
Regeneron were in development of a new drug that would help reduce cholesterol up to 72% more than its competitors. The new drug would target the
661:(cSCC) or locally advanced cSCC who are not candidates for curative surgery or curative radiation. Libtayo was approved by the FDA in September 2018.
3352:
1891:"Veopoz™ (pozelimab-bbfg) Receives FDA Approval as the First Treatment for Children and Adults with CHAPLE Disease | Regeneron Pharmaceuticals Inc"
1018:
1542:
3357:
535:
or product approval. California based laboratory, FOMAT, is part of the clinical investigation through their doctors
Augusto and Nicholas Focil.
991:
657:
injection) is a monoclonal antibody targeting the PD-1 pathway as a checkpoint inhibitor, for the treatment of people with metastatic cutaneous
1217:
1056:
479:
917:
426:
of the 2010s, with a total return of 1,457%. Regeneron
Pharmaceuticals was home to the two highest-paid pharmaceutical executives as of 2020.
1736:
1486:"Regeneron Announces Manufacturing and Supply Agreement for BARDA and U.S. Department of Defense for REGN-COV2 Anti-Viral Antibody Cocktail"
895:
1904:
547:
1455:"HHS, DOD Collaborate with Regeneron on Large-Scale Manufacturing Demonstration Project of COVID-19 Investigational Therapeutic Treatment"
1349:
650:
approved by the FDA in May 2017. Trials commenced in March 2020 to evaluate the effectiveness of
Kevzara in the treatment of COVID-19.
1280:"Regeneron to Acquire Checkmate Pharmaceuticals and Its Investigational Immune Activator for Potential Use in Multiple Tumor Types"
1664:
3342:
899:
1315:
Regeneron
Pharmaceuticals Purchases Avon in Suffern For $ 38.875 Million, To be Used For Research & Development Laboratories
1850:
1196:
1167:
3337:
2799:
515:, an artificial "antibody cocktail" which was then undergoing clinical trials for its potential both to treat people with
1380:
3347:
1914:
1903:
Susana Magadán Mompó and África González-Fernández. "Human Monoclonal Antibodies from Transgenic Mice". Chapter 13 in
1246:
231:
1095:
665:
1569:"Analysis | The Health 202: Trump is taking Regeneron's new coronavirus treatment. It's used for mild symptoms"
2766:
1926:
1609:
1326:
447:
437:
treatments, and Regeneron would retain the right to set prices and control production. This deal was criticized in
3382:
875:
511:, Regeneron was awarded a $ 450 million government contract to manufacture and supply its experimental treatment
527:(BARDA), the DoD Joint Program Executive Office for Chemical, Biological, Radiological and Nuclear Defense, and
2951:
2634:
356:
and their regenerative capabilities, giving rise to its name, the company branched out into the study of both
2173:
613:
1975:
2392:
1856:
1834:
1714:
1710:
1692:
1688:
1133:
677:
563:
349:
2749:
2203:
532:
1247:"Sanofi intends to sell its equity investment in Regeneron; confirms no change to ongoing collaboration"
624:(LDL) cholesterol. Approved by the FDA in July 2015, It is reported to cost $ 4,500 to $ 8,000 per year.
562:
request (as clinical trials had not yet been completed and the drug had not yet been approved by the US
2198:
3191:
2372:
2342:
2255:
2240:
2178:
2123:
707:
422:. REGN2810 was later named cemiplimab. In 2019, Regeneron Pharmaceuticals was announced the 7th best
17:
1774:
1737:"A $ 14,000 cholesterol drug gets a price cut as Regeneron, Sanofi strike deal with Express Scripts"
1510:
1265:
1232:
1209:
1079:
1041:
942:
2792:
2704:
2639:
2347:
2088:
849:
are reported to hold $ 1.3 billion and $ 900 million in company stock, respectively. Both are from
543:
528:
200:
1543:"Trump taking Regeneron drug, Remdesivir therapy for coronavirus diagnosis: ex-WH doctor explains"
2851:
2554:
2275:
2265:
2260:
2118:
2058:
1583:
1520:
1302:"Regeneron to Acquire Decibel Therapeutics, Strengthening Gene Therapy and Hearing Loss Programs"
1101:
658:
621:
443:. Such deals are not unusual for routine drug development in the American pharmaceutical market.
193:
1988:
3301:
3296:
3186:
3156:
3116:
2936:
2926:
2659:
2629:
2579:
2534:
2382:
2073:
854:
695:
109:
2734:
2539:
2357:
2322:
2168:
2148:
681:
491:
3266:
3136:
2966:
2694:
2669:
2619:
2614:
2594:
2544:
2477:
2467:
2337:
2312:
2220:
2215:
2183:
2113:
2083:
1811:"Evaluation of the Efficacy and Safety of Sarilumab in Hospitalized Patients With COVID-19"
647:
508:
353:
220:
1197:
https://markets.ft.com/data/announce/full?dockey=1330-8992408en-4SB6JLTDIDJHOAC14KRIJ3Q6L8
46:
8:
3111:
2785:
2719:
2684:
2674:
2599:
2584:
2307:
2302:
2043:
2033:
858:
501:
166:
321:
3241:
3206:
3181:
3121:
3081:
3061:
3006:
2644:
2457:
2427:
2377:
2143:
2128:
1669:
1139:
1057:"UPDATED: Struggling Sanofi paying $ 1.8B to partner with Regeneron on immuno-oncology"
846:
551:
439:
381:
153:
1829:"FDA approves first treatment for advanced form of the second most common skin cancer"
3281:
3141:
2876:
2624:
2589:
2078:
1910:
699:
635:. It was approved by the FDA in March 2017 and is reported to cost $ 37,000 per year.
632:
598:
559:
472:
377:
148:
81:
2777:
702:
activation. In August 2023, it was approved by the FDA for children and adults with
3291:
3166:
3086:
2916:
2846:
2352:
2290:
2270:
2225:
2210:
2153:
1970:
850:
580:
282:
1810:
3091:
3051:
3046:
3021:
2991:
2699:
2609:
2604:
2245:
2193:
2163:
1401:
617:
361:
114:
3286:
3131:
3066:
2861:
2529:
2235:
703:
60:
1636:"Biopharma Companies With COVID-19 Treatments See $ 10 Billion Market in 2021"
3331:
3306:
3171:
3126:
3041:
2841:
2826:
2709:
2507:
2409:
2317:
1877:
643:
500:, which already worked with Regeneron, announced that Regeneron would pursue
468:
400:
345:
342:
68:
3161:
3101:
2976:
2906:
2886:
2881:
2487:
1405:
539:
464:
In August 2023, Regeneron announced it would acquire Decibel Therapeutics.
1373:"Regeneron's antibody drug added to UK Recovery trial of COVID treatments"
3311:
3276:
3271:
3246:
3096:
3011:
2986:
2891:
2679:
2362:
2230:
594:
587:
461:
for around $ 250 million, enhancing its number of immuno-oncology drugs.
388:
1168:"Regeneron partners with US government to develop coronavirus treatment"
3256:
2871:
2821:
2809:
2739:
2367:
2098:
1980:
1763:(Press release). Regeneron Pharmaceuticals Inc. – via PRNewswire.
1707:"FDA approves Praluent to treat certain patients with high cholesterol"
669:
654:
605:
576:
520:
396:
248:
92:
86:
871:
Biotech and pharmaceutical companies in the New York metropolitan area
3251:
3221:
3146:
3106:
3056:
2956:
2896:
2689:
2559:
2332:
2297:
2158:
2133:
691:
639:
628:
555:
512:
1792:
1429:
3261:
3231:
3036:
3031:
3016:
2921:
2901:
2569:
2564:
2447:
2437:
2108:
516:
475:
to be used for cold storage, research and development laboratories
434:
419:
357:
1610:"Statement on REGN-COV2 Emergency Use Authorization Request (PDF)"
631:
injection) is for the treatment of adolescent and adult patients'
3316:
3226:
3211:
3151:
2996:
2961:
2724:
2574:
2497:
2417:
2387:
2285:
2250:
2188:
2103:
2063:
2048:
2018:
1876:
This article incorporates text from this source, which is in the
1515:
966:"Regeneron's Billionaire Founder Battles The Drug Pricing System"
37:
896:"Regeneron Pharmaceuticals, Inc. 2023 Annual Report (Form 10-K)"
857:. Yancopoulos was a post-doctoral fellow, and MD/PhD student at
694:(pozelimab-bbfg) is a fully human monoclonal antibody targeting
3216:
3201:
3196:
3176:
3076:
3026:
3001:
2981:
2971:
2941:
2911:
2836:
2729:
2664:
2654:
2549:
2280:
2093:
2038:
1933:. MacroTrends. Table (Regeneron Pharmaceuticals Annual Revenue)
1327:"Novartis, Ono Latest to Announce Billion-Dollar M&A Deals"
922:
609:
407:
77:
1210:"U.S.' Regeneron to buy back $ 5 billion stake held by Sanofi"
1019:"Regeneron, Sanofi Launch $ 2B+ Immuno-Oncology Collaboration"
364:
receptors, which gave rise to their first product, which is a
3071:
2946:
2866:
2856:
2744:
2714:
2649:
2138:
2068:
2053:
1909:
Ed. Michael Steinitz. Springer Science+Business Media, 2014.
992:"Sanofi-Regeneron Drug Lowers Cholesterol Up to 72% in Study"
673:
608:) is indicated as an adjunct to diet and maximally tolerated
423:
411:
312:
265:
1957:
2524:
1342:"HHS, Regeneron Collaborate to Develop 2019-nCoV Treatment"
392:
365:
1511:"2 ecuatorianos, cerca del medicamento contra el Covid-19"
1131:
Mazzucato, Mariana; Momenghalibaf, Azzi (March 18, 2020).
1096:"10 Stocks That Had Better Decades Than Amazon and Google"
352:. The company was founded in 1988. Originally focused on
2931:
2831:
646:(IL-6) receptor antagonist for treatment of adults with
1685:"FDA approves Zaltrap for metastatic colorectal cancer"
861:. Yancopoulos was involved in each drug's development.
523:
coronavirus infection. The $ 450 million came from the
457:
In April 2022, the business announced it would acquire
1130:
918:"How Two Guys From Queens Are Changing Drug Discovery"
612:
therapy for the treatment of adults with heterozygous
525:
Biomedical Advanced Research and Development Authority
485:
431:
Biomedical Advanced Research and Development Authority
2807:
1134:"Drug Companies Will Make a Killing From Coronavirus"
1927:"Regeneron Pharmaceuticals Revenue 2006–2021 | REGN"
853:. Schleifer was formerly a professor of medicine at
1966:Business data for Regeneron Pharmaceuticals, Inc.:
1906:Human Monoclonal Antibodies: Methods and Protocols
1406:"Antibody treatment to be given to Covid patients"
1132:
1094:
583:conditions. Approved by the FDA in February 2008.
3329:
1665:"Regulators Approve a Drug for an Eye Condition"
429:In October 2017, Regeneron made a deal with the
3388:Companies associated with the COVID-19 pandemic
3378:Health care companies based in New York (state)
3373:Companies based in Westchester County, New York
915:
558:. His doctors obtained it from Regeneron via a
1851:"FDA Approves First Treatment for Ebola Virus"
3398:Pharmaceutical companies of the United States
2793:
2020:Pharmaceutical companies of the United States
2004:
1452:
1339:
960:
958:
956:
954:
952:
3393:Pharmaceutical companies established in 1988
3368:Biotechnology companies of the United States
2408:
1023:Genetic Engineering & Biotechnology News
911:
909:
548:Walter Reed National Military Medical Center
498:U.S. Department of Health and Human Services
406:On March 26, 2012, Bloomberg announced that
3363:Biotechnology companies established in 1988
1677:
620:(ASCVD) who require additional lowering of
2800:
2786:
2011:
1997:
1282:(Press release). Regeneron. April 19, 2022
1165:
949:
320:
45:
1657:
1607:
1509:Largacha, María Cecilia (6 August 2020).
1483:
906:
684:for the treatment of infection caused by
1508:
727:
467:In December 2023, Regeneron acquired an
3353:1988 establishments in New York (state)
1793:"Regeneron's COVID-19 Response Efforts"
1734:
1633:
1430:"Regeneron's COVID-19 Response Efforts"
1400:
1370:
1207:
1054:
1029:from the original on September 21, 2020
900:U.S. Securities and Exchange Commission
714:
14:
3358:American companies established in 1988
3330:
1843:
1673:. Associated Press. November 18, 2011.
1566:
1178:from the original on February 27, 2020
1109:from the original on December 18, 2019
710:-deficient protein-losing enteropathy.
618:atherosclerotic cardiovascular disease
446:In 2019, the company was added to the
2781:
1992:
1691:(FDA). August 3, 2012. Archived from
1581:
1220:from the original on October 18, 2020
1126:
1124:
1092:
1016:
724:candidates addressing these targets.
1634:Conover, Damien (January 19, 2021).
1166:Pagliarulo, Ned (February 4, 2020).
569:
538:In October 2020 when U.S. President
478:In April 2024, the company acquired
448:Dow Jones Sustainability World Index
1571:– via www.washingtonpost.com.
1174:. Washington, D.C.: Industry Dive.
1147:from the original on March 18, 2020
930:from the original on March 16, 2014
916:Herper, Matthew (August 14, 2013).
845:The founders Leonard Schleifer and
601:approved by the FDA in August 2012.
486:Experimental treatment for COVID-19
24:
2298:Pharmaceutical Product Development
1208:Protard, Matthieu (May 25, 2020).
1121:
888:
720:immunoglobulin-G constant region.
597:injection) is used for metastatic
371:
25:
3409:
1949:
1340:News Division (4 February 2020).
1093:Hough, Jack (December 18, 2019).
676:virus. In October 2020, the U.S.
666:atoltivimab/maftivimab/odesivimab
2767:List of pharmaceutical companies
1871:
1861:(Press release). 14 October 2020
1582:Trump, Donald (7 October 2020).
1264:
1231:
1078:
1067:from the original on May 4, 2016
1040:
941:
289:
288:
272:
271:
255:
254:
238:
237:
215:
214:
36:
1919:
1897:
1883:
1821:
1803:
1785:
1767:
1753:
1728:
1699:
1627:
1601:
1584:"A Message From The President!"
1575:
1560:
1535:
1523:from the original on 2021-12-21
1502:
1477:
1446:
1422:
1394:
1364:
1333:
1319:
1308:
1294:
1272:
1239:
1201:
1190:
1055:Carroll, John (July 28, 2015).
876:Regeneron Science Talent Search
376:The company was founded by CEO
339:Regeneron Pharmaceuticals, Inc.
330:Footnotes / references
31:Regeneron Pharmaceuticals, Inc.
3343:Companies listed on the Nasdaq
2952:Coca-Cola Europacific Partners
1779:Regeneron Pharmaceuticals Inc.
1549:. Associated Press. 2020-10-03
1159:
1086:
1048:
1010:
984:
27:American biotechnology company
13:
1:
2174:Institute for OneWorld Health
1797:Regeneron Pharmaceuticals Inc
1614:Regeneron Pharmaceuticals Inc
1490:Regeneron Pharmaceuticals Inc
1453:News Division (6 July 2020).
1434:Regeneron Pharmaceuticals Inc
881:
840:
614:familial hypercholesterolemia
579:) is used for specific, rare
2393:West Pharmaceutical Services
1857:Food and Drug Administration
1839:(Press release). 2019-09-11.
1835:Food and Drug Administration
1711:Food and Drug Administration
1689:Food and Drug Administration
1608:Regeneron (7 October 2020).
1567:Cunningham, Paige Winfield.
1371:Kelland, Kate (2020-09-14).
855:Weill Cornell Medical School
678:Food and Drug Administration
672:, developed to treat deadly
564:Food and Drug Administration
350:Westchester County, New York
7:
3338:Companies in the Nasdaq-100
1735:Tirrell, Meg (2018-05-01).
864:
533:emergency use authorization
129:; 36 years ago
10:
3414:
2199:McNeil Consumer Healthcare
680:(FDA) approved it with an
668:) is a drug made of three
489:
3348:Regeneron Pharmaceuticals
2817:
2762:
2705:Smith, Kline & French
2517:
2401:
2256:Northwest Biotherapeutics
2241:Merrimack Pharmaceuticals
2026:
1484:Regeneron (7 July 2020).
496:On February 4, 2020, the
459:Checkmate Pharmaceuticals
328:
307:
297:
280:
263:
246:
229:
210:
183:
173:
162:
141:
123:
102:
66:
56:
44:
35:
1216:. Ed. John Stonestreet.
698:, a protein involved in
529:Army Contracting Command
387:Regeneron has developed
293:US$ 25.97 billion (2023)
276:US$ 33.08 billion (2023)
1017:Staff (July 28, 2015).
659:squamous cell carcinoma
622:low-density lipoprotein
259:US$ 3.95 billion (2023)
242:US$ 4.05 billion (2023)
3383:Life sciences industry
3302:Warner Bros. Discovery
3157:Mondelez International
3117:Marriott International
2937:Charter Communications
2630:Leiner Health Products
2074:Amneal Pharmaceuticals
1709:(Press release). U.S.
1687:(Press release). U.S.
554:, he was administered
2184:Johnson & Johnson
1713:(FDA). Archived from
1383:on September 17, 2020
1290:– via BioSpace.
728:Financial performance
502:monoclonal antibodies
492:Casirivimab/imdevimab
3267:Take-Two Interactive
2967:Constellation Energy
2478:Jazz Pharmaceuticals
2468:Horizon Therapeutics
2338:Sarepta Therapeutics
2313:Proteon Therapeutics
2308:Procter & Gamble
2221:Melinta Therapeutics
2114:Bristol Myers Squibb
1817:. 30 September 2020.
715:Technology platforms
696:complement factor C5
648:rheumatoid arthritis
509:Operation Warp Speed
507:In July 2020, under
354:neurotrophic factors
199:George Yancopoulos (
3187:O'Reilly Auto Parts
2685:Repros Therapeutics
2600:Forest Laboratories
2585:Cutter Laboratories
2303:Prasco Laboratories
2044:Acorda Therapeutics
2034:Abbott Laboratories
1465:on 18 December 2020
902:. February 5, 2024.
859:Columbia University
504:to fight COVID-19.
299:Number of employees
192:Leonard Schleifer (
167:Tarrytown, New York
32:
3242:Roper Technologies
3207:Palo Alto Networks
3082:Intuitive Surgical
3062:Idexx Laboratories
3007:Diamondback Energy
2645:Miles Laboratories
2635:Martek Biosciences
2458:Endo International
2378:Ventria Bioscience
2144:Danco Laboratories
1893:. August 18, 2023.
1815:clinicaltrials.gov
1670:The New York Times
1352:on 22 January 2021
1140:The New York Times
847:George Yancopoulos
552:Bethesda, Maryland
542:was infected with
440:The New York Times
382:George Yancopoulos
154:George Yancopoulos
30:
3325:
3324:
3282:Texas Instruments
2877:Applied Materials
2808:Companies of the
2775:
2774:
2758:
2757:
2590:DNAPrint Genomics
2079:Avax Technologies
1695:on June 25, 2013.
838:
837:
700:complement system
642:injection) is an
633:atopic dermatitis
599:colorectal cancer
570:Marketed products
560:compassionate use
473:Suffern, New York
378:Leonard Schleifer
348:headquartered in
336:
335:
149:Leonard Schleifer
16:(Redirected from
3405:
3167:Monster Beverage
3087:Keurig Dr Pepper
2917:Booking Holdings
2802:
2795:
2788:
2779:
2778:
2406:
2405:
2353:Tec Laboratories
2226:Melior Discovery
2211:Kinetic Concepts
2154:Galena Biopharma
2013:
2006:
1999:
1990:
1989:
1961:
1960:
1958:Official website
1943:
1942:
1940:
1938:
1923:
1917:
1901:
1895:
1894:
1887:
1881:
1875:
1874:
1870:
1868:
1866:
1847:
1841:
1840:
1825:
1819:
1818:
1807:
1801:
1800:
1789:
1783:
1782:
1781:(Press release).
1771:
1765:
1764:
1757:
1751:
1750:
1748:
1747:
1732:
1726:
1725:
1723:
1722:
1703:
1697:
1696:
1681:
1675:
1674:
1661:
1655:
1654:
1652:
1651:
1642:. Archived from
1631:
1625:
1624:
1622:
1620:
1605:
1599:
1598:
1596:
1594:
1579:
1573:
1572:
1564:
1558:
1557:
1555:
1554:
1547:Associated Press
1539:
1533:
1532:
1530:
1528:
1506:
1500:
1499:
1497:
1496:
1481:
1475:
1474:
1472:
1470:
1461:. Archived from
1450:
1444:
1443:
1441:
1440:
1426:
1420:
1419:
1417:
1416:
1402:Morelle, Rebecca
1398:
1392:
1391:
1389:
1388:
1379:. Archived from
1368:
1362:
1361:
1359:
1357:
1348:. Archived from
1337:
1331:
1330:
1323:
1317:
1312:
1306:
1305:
1304:. 9 August 2023.
1298:
1292:
1291:
1289:
1287:
1276:
1270:
1269:
1268:
1262:
1260:
1258:
1243:
1237:
1236:
1235:
1229:
1227:
1225:
1205:
1199:
1194:
1188:
1187:
1185:
1183:
1163:
1157:
1156:
1154:
1152:
1136:
1128:
1119:
1118:
1116:
1114:
1098:
1090:
1084:
1083:
1082:
1076:
1074:
1072:
1052:
1046:
1045:
1044:
1038:
1036:
1034:
1014:
1008:
1007:
1005:
1003:
988:
982:
981:
979:
977:
962:
947:
946:
945:
939:
937:
935:
913:
904:
903:
892:
851:Queens, New York
732:
731:
686:Zaire ebolavirus
581:autoinflammatory
324:
319:
316:
314:
292:
291:
285:
275:
274:
268:
258:
257:
241:
240:
232:Operating income
224:
218:
217:
137:
135:
130:
49:
40:
33:
29:
21:
3413:
3412:
3408:
3407:
3406:
3404:
3403:
3402:
3328:
3327:
3326:
3321:
3052:GlobalFoundries
3022:Electronic Arts
2813:
2806:
2776:
2771:
2754:
2700:Schering-Plough
2610:ImClone Systems
2513:
2397:
2246:Myriad Genetics
2236:Merck & Co.
2194:Janssen Biotech
2164:Gilead Sciences
2022:
2017:
1985:
1956:
1955:
1952:
1947:
1946:
1936:
1934:
1925:
1924:
1920:
1902:
1898:
1889:
1888:
1884:
1872:
1864:
1862:
1849:
1848:
1844:
1827:
1826:
1822:
1809:
1808:
1804:
1791:
1790:
1786:
1773:
1772:
1768:
1759:
1758:
1754:
1745:
1743:
1733:
1729:
1720:
1718:
1705:
1704:
1700:
1683:
1682:
1678:
1663:
1662:
1658:
1649:
1647:
1640:Morningstar.com
1632:
1628:
1618:
1616:
1606:
1602:
1592:
1590:
1580:
1576:
1565:
1561:
1552:
1550:
1541:
1540:
1536:
1526:
1524:
1507:
1503:
1494:
1492:
1482:
1478:
1468:
1466:
1451:
1447:
1438:
1436:
1428:
1427:
1423:
1414:
1412:
1399:
1395:
1386:
1384:
1369:
1365:
1355:
1353:
1338:
1334:
1329:. 5 March 2024.
1325:
1324:
1320:
1313:
1309:
1300:
1299:
1295:
1285:
1283:
1278:
1277:
1273:
1263:
1256:
1254:
1245:
1244:
1240:
1230:
1223:
1221:
1206:
1202:
1195:
1191:
1181:
1179:
1164:
1160:
1150:
1148:
1129:
1122:
1112:
1110:
1091:
1087:
1077:
1070:
1068:
1053:
1049:
1039:
1032:
1030:
1015:
1011:
1001:
999:
998:. 26 March 2012
990:
989:
985:
975:
973:
964:
963:
950:
940:
933:
931:
914:
907:
894:
893:
889:
884:
867:
843:
834:$ 13.1 billion
826:$ 12.2 billion
818:$ 16.1 billion
730:
717:
572:
519:and to prevent
494:
488:
418:development of
395:inhibitor, and
374:
372:Company history
362:tyrosine kinase
341:is an American
332:
311:
300:
281:
264:
251:
234:
219:
206:
186:
176:
158:
133:
131:
128:
119:
110:Pharmaceuticals
98:
71:
52:
28:
23:
22:
15:
12:
11:
5:
3411:
3401:
3400:
3395:
3390:
3385:
3380:
3375:
3370:
3365:
3360:
3355:
3350:
3345:
3340:
3323:
3322:
3320:
3319:
3314:
3309:
3304:
3299:
3294:
3289:
3284:
3279:
3274:
3269:
3264:
3259:
3254:
3249:
3244:
3239:
3234:
3229:
3224:
3219:
3214:
3209:
3204:
3199:
3194:
3189:
3184:
3179:
3174:
3169:
3164:
3159:
3154:
3149:
3144:
3139:
3134:
3129:
3124:
3119:
3114:
3109:
3104:
3099:
3094:
3089:
3084:
3079:
3074:
3069:
3064:
3059:
3054:
3049:
3044:
3039:
3034:
3029:
3024:
3019:
3014:
3009:
3004:
2999:
2994:
2989:
2984:
2979:
2974:
2969:
2964:
2959:
2954:
2949:
2944:
2939:
2934:
2929:
2924:
2919:
2914:
2909:
2904:
2899:
2894:
2889:
2884:
2879:
2874:
2869:
2864:
2862:Analog Devices
2859:
2854:
2849:
2844:
2839:
2834:
2829:
2824:
2818:
2815:
2814:
2805:
2804:
2797:
2790:
2782:
2773:
2772:
2770:
2769:
2763:
2760:
2759:
2756:
2755:
2753:
2752:
2747:
2742:
2737:
2732:
2727:
2722:
2717:
2712:
2707:
2702:
2697:
2692:
2687:
2682:
2677:
2672:
2667:
2662:
2657:
2652:
2647:
2642:
2637:
2632:
2627:
2622:
2617:
2612:
2607:
2602:
2597:
2592:
2587:
2582:
2577:
2572:
2567:
2562:
2557:
2552:
2547:
2542:
2537:
2532:
2530:Allergan, Inc.
2527:
2521:
2519:
2515:
2514:
2512:
2511:
2510:(Canada, 2010)
2505:
2495:
2485:
2475:
2465:
2455:
2445:
2435:
2425:
2414:
2412:
2403:
2399:
2398:
2396:
2395:
2390:
2385:
2380:
2375:
2370:
2365:
2360:
2355:
2350:
2345:
2340:
2335:
2330:
2325:
2320:
2315:
2310:
2305:
2300:
2295:
2294:
2293:
2288:
2278:
2273:
2268:
2263:
2261:Norwich Pharma
2258:
2253:
2248:
2243:
2238:
2233:
2228:
2223:
2218:
2213:
2208:
2207:
2206:
2201:
2196:
2191:
2181:
2176:
2171:
2166:
2161:
2156:
2151:
2146:
2141:
2136:
2131:
2126:
2121:
2116:
2111:
2106:
2101:
2096:
2091:
2086:
2081:
2076:
2071:
2066:
2061:
2056:
2051:
2046:
2041:
2036:
2030:
2028:
2024:
2023:
2016:
2015:
2008:
2001:
1993:
1987:
1986:
1984:
1983:
1978:
1973:
1967:
1964:
1962:
1951:
1950:External links
1948:
1945:
1944:
1931:Stock Research
1918:
1915:978-1627035859
1896:
1882:
1842:
1820:
1802:
1784:
1766:
1752:
1727:
1698:
1676:
1656:
1626:
1600:
1574:
1559:
1534:
1501:
1476:
1445:
1421:
1404:(2020-09-14).
1393:
1363:
1332:
1318:
1307:
1293:
1271:
1253:. May 25, 2020
1238:
1200:
1189:
1172:BioPharma Dive
1158:
1120:
1085:
1047:
1009:
983:
972:. 26 July 2018
948:
905:
886:
885:
883:
880:
879:
878:
873:
866:
863:
842:
839:
836:
835:
832:
828:
827:
824:
820:
819:
816:
812:
811:
810:$ 8.5 billion
808:
804:
803:
802:$ 7.8 billion
800:
796:
795:
794:$ 6.7 billion
792:
788:
787:
786:$ 5.8 billion
784:
780:
779:
778:$ 4.8 billion
776:
772:
771:
770:$ 4.1 billion
768:
764:
763:
762:$ 2.8 billion
760:
756:
755:
754:$ 2.1 billion
752:
748:
747:
746:$ 1.4 billion
744:
740:
739:
736:
735:Financial Year
729:
726:
716:
713:
712:
711:
704:CHAPLE disease
689:
662:
651:
636:
625:
602:
591:
584:
571:
568:
490:Main article:
487:
484:
380:and scientist
373:
370:
334:
333:
326:
325:
309:
305:
304:
301:
298:
295:
294:
286:
278:
277:
269:
261:
260:
252:
247:
244:
243:
235:
230:
227:
226:
212:
208:
207:
205:
204:
197:
189:
187:
184:
181:
180:
177:
174:
171:
170:
164:
160:
159:
157:
156:
151:
145:
143:
139:
138:
125:
121:
120:
118:
117:
112:
106:
104:
100:
99:
97:
96:
90:
84:
74:
72:
67:
64:
63:
58:
54:
53:
50:
42:
41:
26:
9:
6:
4:
3:
2:
3410:
3399:
3396:
3394:
3391:
3389:
3386:
3384:
3381:
3379:
3376:
3374:
3371:
3369:
3366:
3364:
3361:
3359:
3356:
3354:
3351:
3349:
3346:
3344:
3341:
3339:
3336:
3335:
3333:
3318:
3315:
3313:
3310:
3308:
3305:
3303:
3300:
3298:
3295:
3293:
3290:
3288:
3285:
3283:
3280:
3278:
3275:
3273:
3270:
3268:
3265:
3263:
3260:
3258:
3255:
3253:
3250:
3248:
3245:
3243:
3240:
3238:
3235:
3233:
3230:
3228:
3225:
3223:
3220:
3218:
3215:
3213:
3210:
3208:
3205:
3203:
3200:
3198:
3195:
3193:
3190:
3188:
3185:
3183:
3180:
3178:
3175:
3173:
3170:
3168:
3165:
3163:
3160:
3158:
3155:
3153:
3150:
3148:
3145:
3143:
3140:
3138:
3135:
3133:
3130:
3128:
3127:Mercado Libre
3125:
3123:
3120:
3118:
3115:
3113:
3110:
3108:
3105:
3103:
3100:
3098:
3095:
3093:
3090:
3088:
3085:
3083:
3080:
3078:
3075:
3073:
3070:
3068:
3065:
3063:
3060:
3058:
3055:
3053:
3050:
3048:
3045:
3043:
3042:GE HealthCare
3040:
3038:
3035:
3033:
3030:
3028:
3025:
3023:
3020:
3018:
3015:
3013:
3010:
3008:
3005:
3003:
3000:
2998:
2995:
2993:
2990:
2988:
2985:
2983:
2980:
2978:
2975:
2973:
2970:
2968:
2965:
2963:
2960:
2958:
2955:
2953:
2950:
2948:
2945:
2943:
2940:
2938:
2935:
2933:
2930:
2928:
2925:
2923:
2920:
2918:
2915:
2913:
2910:
2908:
2905:
2903:
2900:
2898:
2895:
2893:
2890:
2888:
2885:
2883:
2880:
2878:
2875:
2873:
2870:
2868:
2865:
2863:
2860:
2858:
2855:
2853:
2850:
2848:
2845:
2843:
2840:
2838:
2835:
2833:
2830:
2828:
2825:
2823:
2820:
2819:
2816:
2811:
2803:
2798:
2796:
2791:
2789:
2784:
2783:
2780:
2768:
2765:
2764:
2761:
2751:
2748:
2746:
2743:
2741:
2738:
2736:
2733:
2731:
2728:
2726:
2723:
2721:
2718:
2716:
2713:
2711:
2710:Sterling Drug
2708:
2706:
2703:
2701:
2698:
2696:
2693:
2691:
2688:
2686:
2683:
2681:
2678:
2676:
2673:
2671:
2668:
2666:
2663:
2661:
2658:
2656:
2653:
2651:
2648:
2646:
2643:
2641:
2638:
2636:
2633:
2631:
2628:
2626:
2623:
2621:
2618:
2616:
2613:
2611:
2608:
2606:
2603:
2601:
2598:
2596:
2593:
2591:
2588:
2586:
2583:
2581:
2578:
2576:
2573:
2571:
2568:
2566:
2563:
2561:
2558:
2556:
2553:
2551:
2548:
2546:
2543:
2541:
2538:
2536:
2533:
2531:
2528:
2526:
2523:
2522:
2520:
2516:
2509:
2508:Bausch Health
2506:
2503:
2499:
2496:
2493:
2489:
2486:
2483:
2479:
2476:
2473:
2469:
2466:
2463:
2459:
2456:
2453:
2449:
2446:
2443:
2439:
2436:
2433:
2429:
2426:
2423:
2419:
2416:
2415:
2413:
2411:
2410:Tax inversion
2407:
2404:
2400:
2394:
2391:
2389:
2386:
2384:
2381:
2379:
2376:
2374:
2371:
2369:
2366:
2364:
2361:
2359:
2356:
2354:
2351:
2349:
2346:
2344:
2341:
2339:
2336:
2334:
2331:
2329:
2326:
2324:
2321:
2319:
2318:Purdue Pharma
2316:
2314:
2311:
2309:
2306:
2304:
2301:
2299:
2296:
2292:
2289:
2287:
2284:
2283:
2282:
2279:
2277:
2274:
2272:
2269:
2267:
2264:
2262:
2259:
2257:
2254:
2252:
2249:
2247:
2244:
2242:
2239:
2237:
2234:
2232:
2229:
2227:
2224:
2222:
2219:
2217:
2214:
2212:
2209:
2205:
2202:
2200:
2197:
2195:
2192:
2190:
2187:
2186:
2185:
2182:
2180:
2177:
2175:
2172:
2170:
2167:
2165:
2162:
2160:
2157:
2155:
2152:
2150:
2147:
2145:
2142:
2140:
2137:
2135:
2132:
2130:
2127:
2125:
2122:
2120:
2117:
2115:
2112:
2110:
2107:
2105:
2102:
2100:
2097:
2095:
2092:
2090:
2087:
2085:
2082:
2080:
2077:
2075:
2072:
2070:
2067:
2065:
2062:
2060:
2057:
2055:
2052:
2050:
2047:
2045:
2042:
2040:
2037:
2035:
2032:
2031:
2029:
2025:
2021:
2014:
2009:
2007:
2002:
2000:
1995:
1994:
1991:
1982:
1979:
1977:
1974:
1972:
1969:
1968:
1965:
1963:
1959:
1954:
1953:
1932:
1928:
1922:
1916:
1912:
1908:
1907:
1900:
1892:
1886:
1879:
1878:public domain
1860:
1858:
1852:
1846:
1838:
1836:
1830:
1824:
1816:
1812:
1806:
1798:
1794:
1788:
1780:
1776:
1770:
1762:
1756:
1742:
1738:
1731:
1717:on 2015-07-27
1716:
1712:
1708:
1702:
1694:
1690:
1686:
1680:
1672:
1671:
1666:
1660:
1646:on 2021-01-20
1645:
1641:
1637:
1630:
1615:
1611:
1604:
1589:
1585:
1578:
1570:
1563:
1548:
1544:
1538:
1522:
1518:
1517:
1512:
1505:
1491:
1487:
1480:
1464:
1460:
1456:
1449:
1435:
1431:
1425:
1411:
1407:
1403:
1397:
1382:
1378:
1374:
1367:
1351:
1347:
1343:
1336:
1328:
1322:
1316:
1311:
1303:
1297:
1281:
1275:
1267:
1252:
1248:
1242:
1234:
1219:
1215:
1211:
1204:
1198:
1193:
1177:
1173:
1169:
1162:
1146:
1142:
1141:
1135:
1127:
1125:
1108:
1104:
1103:
1097:
1089:
1081:
1066:
1062:
1061:FierceBiotech
1058:
1051:
1043:
1028:
1024:
1020:
1013:
997:
993:
987:
971:
967:
961:
959:
957:
955:
953:
944:
929:
925:
924:
919:
912:
910:
901:
897:
891:
887:
877:
874:
872:
869:
868:
862:
860:
856:
852:
848:
833:
830:
829:
825:
822:
821:
817:
814:
813:
809:
806:
805:
801:
798:
797:
793:
790:
789:
785:
782:
781:
777:
774:
773:
769:
766:
765:
761:
758:
757:
753:
750:
749:
745:
742:
741:
737:
734:
733:
725:
721:
709:
705:
701:
697:
693:
690:
687:
683:
679:
675:
671:
667:
663:
660:
656:
652:
649:
645:
644:interleukin-6
641:
637:
634:
630:
626:
623:
619:
615:
611:
607:
603:
600:
596:
592:
589:
585:
582:
578:
574:
573:
567:
565:
561:
557:
553:
549:
546:and taken to
545:
541:
536:
534:
530:
526:
522:
518:
514:
510:
505:
503:
499:
493:
483:
481:
476:
474:
470:
469:Avon Products
465:
462:
460:
455:
451:
449:
444:
442:
441:
436:
432:
427:
425:
421:
415:
413:
409:
404:
402:
401:interleukin-1
398:
394:
390:
385:
383:
379:
369:
367:
363:
359:
355:
351:
347:
344:
343:biotechnology
340:
331:
327:
323:
318:
310:
306:
303:13,450 (2023)
302:
296:
287:
284:
279:
270:
267:
262:
253:
250:
245:
236:
233:
228:
223:13.12 billion
222:
213:
209:
202:
198:
195:
191:
190:
188:
182:
178:
172:
168:
165:
161:
155:
152:
150:
147:
146:
144:
140:
126:
122:
116:
113:
111:
108:
107:
105:
101:
94:
91:
88:
85:
83:
79:
76:
75:
73:
70:
65:
62:
59:
55:
48:
43:
39:
34:
19:
3236:
3222:PDD Holdings
3192:Old Dominion
3102:Lam Research
2907:Baker Hughes
2488:Mallinckrodt
2373:Upsher-Smith
2327:
2204:Ortho-McNeil
1935:. Retrieved
1930:
1921:
1905:
1899:
1885:
1863:. Retrieved
1854:
1845:
1832:
1823:
1814:
1805:
1796:
1787:
1778:
1769:
1755:
1744:. Retrieved
1740:
1730:
1719:. Retrieved
1715:the original
1701:
1693:the original
1679:
1668:
1659:
1648:. Retrieved
1644:the original
1639:
1629:
1617:. Retrieved
1613:
1603:
1591:. Retrieved
1587:
1577:
1562:
1551:. Retrieved
1546:
1537:
1525:. Retrieved
1514:
1504:
1493:. Retrieved
1489:
1479:
1467:. Retrieved
1463:the original
1458:
1448:
1437:. Retrieved
1433:
1424:
1413:. Retrieved
1409:
1396:
1385:. Retrieved
1381:the original
1376:
1366:
1354:. Retrieved
1350:the original
1345:
1335:
1321:
1310:
1296:
1284:. Retrieved
1274:
1257:February 17,
1255:. Retrieved
1250:
1241:
1222:. Retrieved
1213:
1203:
1192:
1180:. Retrieved
1171:
1161:
1149:. Retrieved
1138:
1113:December 19,
1111:. Retrieved
1100:
1088:
1069:. Retrieved
1060:
1050:
1031:. Retrieved
1022:
1012:
1000:. Retrieved
995:
986:
974:. Retrieved
969:
932:. Retrieved
921:
890:
844:
722:
718:
685:
616:or clinical
540:Donald Trump
537:
506:
495:
480:2seventy Bio
477:
471:property in
466:
463:
456:
452:
445:
438:
428:
416:
405:
386:
375:
338:
337:
329:
283:Total equity
266:Total assets
163:Headquarters
57:Company type
51:Headquarters
3312:Xcel Energy
3272:T-Mobile US
3247:Ross Stores
3097:Kraft Heinz
3012:Dollar Tree
2987:CrowdStrike
2892:AstraZeneca
2680:Parke-Davis
2363:Trevena Inc
2231:Mentholatum
2039:AbbVie Inc.
1976:SEC filings
595:aflibercept
588:aflibercept
389:aflibercept
175:Area served
93:S&P 500
3332:Categories
3287:Trade Desk
3257:Supermicro
2810:Nasdaq-100
2740:ViroPharma
2640:Massengill
2368:Ultragenyx
2099:Bioverativ
1865:14 October
1746:2018-08-22
1721:2015-07-29
1650:2021-01-19
1553:2020-10-13
1527:13 October
1495:2020-10-08
1439:2020-10-08
1415:2020-10-08
1387:2020-10-08
1286:October 9,
1224:October 9,
1151:October 9,
1071:October 9,
1033:October 9,
882:References
841:Key people
682:indication
670:antibodies
655:cemiplimab
627:Dupixent (
606:alirocumab
604:Praluent (
577:rilonacept
575:Arcalyst (
521:SARS-CoV-2
397:rilonacept
315:.regeneron
249:Net income
185:Key people
87:Nasdaq-100
3252:Starbucks
3237:Regeneron
3147:Microsoft
3137:Microchip
3112:Lululemon
3057:Honeywell
2957:Cognizant
2897:Atlassian
2690:Qualitest
2560:CancerVax
2343:Sheffield
2333:RespireRx
2328:Regeneron
2179:Intercept
2159:Genentech
2149:Eli Lilly
2134:CytoSport
2124:Ceragenix
1619:8 October
1593:7 October
1469:8 October
1356:8 October
996:Bloomberg
934:March 22,
664:Inmazeb (
653:Libtayo (
640:sarilumab
638:Kevzara (
629:dupilumab
593:Zaltrap (
556:REGN-COV2
513:REGN-COV2
384:in 1988.
95:component
89:component
69:Traded as
18:Regeneron
3262:Synopsys
3232:Qualcomm
3067:Illumina
3037:Fortinet
3032:Fastenal
3017:DoorDash
2922:Broadcom
2902:Autodesk
2842:Alphabet
2570:CoTherix
2565:Cephalon
2448:Covidien
2438:Allergan
2428:Alkermes
2348:Spectrum
2216:McKesson
2109:Biovista
2089:BioCryst
1937:July 26,
1521:Archived
1410:BBC News
1218:Archived
1182:July 25,
1176:Archived
1145:Archived
1107:Archived
1102:Barron's
1065:Archived
1027:Archived
928:Archived
865:See also
738:Revenue
544:COVID-19
517:COVID-19
435:COVID-19
420:REGN2810
358:cytokine
142:Founders
103:Industry
3317:Zscaler
3307:Workday
3227:PepsiCo
3212:Paychex
3172:Netflix
3162:MongoDB
3152:Moderna
3122:Marvell
2997:Datadog
2962:Comcast
2927:Cadence
2725:Trubion
2575:Covance
2555:Bradley
2504:, 2013)
2502:Ireland
2498:Perrigo
2494:, 2013)
2492:Ireland
2484:, 2012)
2482:Ireland
2474:, 2014)
2472:Ireland
2464:, 2014)
2462:Ireland
2454:, 2007)
2452:Ireland
2444:, 2015)
2442:Ireland
2434:, 2011)
2432:Ireland
2424:, 2013)
2422:Ireland
2418:Actavis
2388:Viatris
2286:Hospira
2276:Ovation
2271:Organon
2266:NovaBay
2251:Moderna
2189:Ethicon
2119:Century
2104:Biovest
2064:Alnylam
2059:Alexion
2049:Advaxis
2027:Current
1588:Twitter
1516:YouTube
1459:HHS.gov
1377:Reuters
1346:HHS.gov
1214:Reuters
1002:25 July
976:26 July
586:Eylea (
368:-trap.
346:company
308:Website
211:Revenue
132: (
124:Founded
115:Biotech
80::
3297:Vertex
3292:Verisk
3217:PayPal
3202:Paccar
3197:onsemi
3177:Nvidia
3142:Micron
3077:Intuit
3047:Gilead
3027:Exelon
3002:Dexcom
2982:Costco
2977:CoStar
2972:Copart
2942:Cintas
2912:Biogen
2847:Amazon
2837:Airbnb
2750:Zonite
2730:Upjohn
2665:Nuvelo
2660:Nereus
2655:Naurex
2580:Cubist
2550:Biolex
2535:Amylin
2402:Former
2383:Vertex
2291:Searle
2281:Pfizer
2094:Biogen
2084:Baxter
1981:Yahoo!
1971:Google
1913:
1251:Sanofi
970:Forbes
923:Forbes
692:Veopoz
610:statin
414:gene.
408:Sanofi
225:(2023)
179:Global
169:, U.S.
78:Nasdaq
61:Public
3277:Tesla
3107:Linde
3072:Intel
2947:Cisco
2872:Apple
2867:Ansys
2857:Amgen
2822:Adobe
2812:index
2745:Wyeth
2735:Verus
2715:Tanox
2695:Rib-X
2670:Ortho
2650:Mylan
2605:Genta
2540:ARIAD
2518:Other
2358:Titan
2323:Quark
2169:Ionis
2139:CytRx
2129:Combe
2069:Amgen
2054:Alcon
1859:(FDA)
1855:U.S.
1837:(FDA)
1833:U.S.
674:Ebola
424:stock
412:PCSK9
399:, an
3132:Meta
2887:ASML
2620:King
2615:ISTA
2595:Epix
2545:Barr
2525:Alza
1939:2021
1911:ISBN
1867:2020
1741:CNBC
1621:2020
1595:2020
1529:2020
1471:2020
1358:2020
1288:2022
1259:2023
1226:2022
1184:2021
1153:2022
1115:2019
1073:2022
1035:2022
1004:2021
978:2018
936:2014
831:2023
823:2022
815:2021
807:2020
799:2019
791:2018
783:2017
775:2016
767:2015
759:2014
751:2013
743:2012
708:CD55
393:VEGF
391:, a
366:VEGF
360:and
317:.com
221:US$
134:1988
127:1988
82:REGN
3182:NXP
3092:KLA
2992:CSX
2932:CDW
2882:ARM
2852:AEP
2832:AMD
2827:ADP
2720:TAP
2675:OSI
706:or
550:in
313:www
201:CSO
194:CEO
3334::
2625:KV
1929:.
1853:.
1831:.
1813:.
1795:.
1777:.
1739:.
1667:.
1638:.
1612:.
1586:.
1545:.
1519:.
1513:.
1488:.
1457:.
1432:.
1408:.
1375:.
1344:.
1249:.
1212:.
1170:.
1143:.
1137:.
1123:^
1105:.
1099:.
1063:.
1059:.
1025:.
1021:.
994:.
968:.
951:^
926:.
920:.
908:^
898:.
482:.
450:.
2801:e
2794:t
2787:v
2500:(
2490:(
2480:(
2470:(
2460:(
2450:(
2440:(
2430:(
2420:(
2012:e
2005:t
1998:v
1941:.
1880:.
1869:.
1799:.
1749:.
1724:.
1653:.
1623:.
1597:.
1556:.
1531:.
1498:.
1473:.
1442:.
1418:.
1390:.
1360:.
1261:.
1228:.
1186:.
1155:.
1117:.
1075:.
1037:.
1006:.
980:.
938:.
688:.
203:)
196:)
136:)
20:)
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
.jpg)
