1897:. However, when studies in the 1980s showed how effective the drug was at treating and preventing the disease, the WHO agreed to use it instead of its previous strategies. Merck's involvement is considered a key factor in the success against the disease all over the world, and the decision to donate the entirety of the drug to all those in need of it is used as part of the Mectizan Donation Program that covers countries such as Yemen and African countries. More than 700 million people have been treated since the inception of the program with 80 million people still undergoing treatment in Africa, Latin America, and Yemen. Blindness caused by onchocerciasis is decreasing, and there are regions of Latin America and Africa that have been shown to have eliminated the disease altogether.
1960:
medical and pharmacy records confirming the occurrence of a heart attack, ischemic stroke, or sudden cardiac death; the receipt of at least 30 Vioxx pills within 60 days prior to the injury or death; and confirmation of Vioxx being used within 14 days of the Vioxx-related event. The settlement was generally viewed by industry analysts and investors as a victory for Merck, considering that original estimates of Merck's liability reached between $ 10 billion and $ 25 billion. As of mid-2008, when the plaintiff class had reached the threshold percentage required by Merck to go through with the settlement, plaintiffs had prevailed in only three of the twenty cases that had reached juries, all with relatively small awards.
2135:'s list of pollutants, as a solvent in some of its manufacturing processes. Merck chemists and engineers subsequently replaced the compound with others having fewer negative environmental effects. Merck has also modified its equipment to protect the environment, installing a distributed control system that coordinates chemical reactions more efficiently and expedites manufacturing by 50 percent, eliminating the need for the disposal and storage of harmful waste. Biological oxygen demand has also been reduced. In 2011, Merck paid a $ 1.5 million civil penalty to settle alleged violations of federal environmental laws at its pharmaceutical manufacturing facilities in
67:
670:(ezetimibe) is a drug for hypercholesterolemia that acts by inhibiting the absorption of dietary cholesterol. Zetia has been controversial, as it was initially approved based on its impact on serum cholesterol levels without proof that it actually impacted the incidence of cardiovascular disease. Results of the IMPROVE-IT study, however, introduced at the 2014 Scientific Sessions of the American Heart Association, showed a statistically significant, albeit modest, benefit in adding Zetia to simvastatin for high-risk, post-acute-coronary-syndrome patients.
1131:. Although it gave the appearance of being an independent peer-reviewed journal, without any indication that Merck had paid for it, the journal actually reprinted articles that originally appeared in other publications and that were favorable to Merck. The misleading publication came to light in 2009 during a personal injury lawsuit filed over Vioxx; 9 of 29 articles in the journal's second issue referred positively to Vioxx. The CEO of Elsevier's Health Sciences Division, Michael Hansen, admitted that the practice was "unacceptable".
51:
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1493:, and several other species. Merck’s portfolio will also be complemented by T-cell attractions using the patented Harpoon Tri-specific design for T cell activation (TriTAC). According to engineering protein technology, tumor cells are destroyed by the patient’s own immune cells, and the ProTriTAC platform works with the TriTAC platform to develop a therapeutic agent that attracts T-cells, but is inactive until it reaches the tumor. In April 2024 Merck acquired Abceutics.
813:
664:. It has been popular due in part because unlike many other diabetes drugs, it causes little or no weight gain and is not associated with hypoglycemic episodes. Merck also sells a single pill combination drug containing both Januvia and metformin under the trade name Janumet. There has been some concern that treatment with Januvia and other DPP-IV inhibitors may be associated with a modestly increased risk of pancreatitis.
891:, bought the company back at a U.S. government auction for $ 3.5 million, but Merck & Co. remained a separate company from its former German parent. Merck & Co. holds the trademark rights to the "Merck" name in the United States and Canada, while its former parent company retains the rights in the rest of the world; the right to use the Merck name was the subject of litigation between the two companies in 2016.
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2079:. The case came to a head when a research scientist believed he was communicating with Merck & Co regarding a research grant in oncology, when in fact he was talking with the Merck Group. As a result, Merck & Co. asked the federal court to stop the Merck Group from using "Merck" on any products or marketing materials in the United States. As a direct result, Merck & Co is seeking "
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946:, under the trade name Duiril in 1958. The research leading to the discovery of chlorothiazide, leading to "the saving of untold thousands of lives and the alleviation of the suffering of millions of victims of hypertension" was recognized by a special Public Health Award from the Lasker Foundation in 1975.
858:
In 1887 a German-born, long-time Merck employee, Theodore
Weicker, went to the United States to represent Merck Group. In 1891, with $ 200,000 received from E. Merck, Weicker started Merck & Co., with headquarters in lower Manhattan. That year George Merck, the 23-year-old son of the then head of
2074:
In response to the ruling, MSD initiated counter-litigation in the United States in
January 2016 by filing a federal lawsuit which accused its former parent company of "infringing on its trademark" through actions that included the increased usage of "Merck KGaA" and "MERCK" in branding in the US as
1967:
According to internal e-mail traffic released at a later lawsuit, Merck had a list of doctors critical of Vioxx to be "neutralized" or "discredited". "We may need to seek them out and destroy them where they live," wrote an employee. A Stanford
Medical School professor said that Merck was engaged in
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caused persistent sexual dysfunction in men. The drug has been linked to over 700 incidences of suicidal thoughts and 110 deaths. Merck has been receiving reports since 1998, but never included the risks on the label. In 2015, Merck was sued by consumer-rights law firm Hagens Berman over a wrongful
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it was conducting that included findings of increased risk of heart attacks among Vioxx users who had been using the medication for over eighteen months. On
September 28, 2004, Merck notified the FDA that it was voluntarily withdrawing Vioxx from the market, and it publicly announced the withdrawal
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to develop artificial intelligence-powered digital pathology diagnostics that could be used to identify patients suitable for immunotherapies. The aim is to come up with tools that can pre-screen patients with four tumour types for the MSI-H biomarker, namely endometrial, gastric, small intestinal,
1221:
In
January 2016, Merck announced two new partnerships; the first with Quartet Medicine and its small molecule pain treatments, the second with Complix investigating intracellular cancer targets, with both collaborations potentially generating up to $ 595 million and $ 280 million respectively. Days
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About 50,000 people sued Merck, claiming they or their family members had suffered medical problems such as heart attacks or strokes after taking Vioxx. In
November 2007, Merck agreed to pay $ 4.85 billion to settle most of the pending Vioxx lawsuits. The settlement required that claimants provide
2050:, and instead of "Merck Group", the "EMD Group" name is used. In the United States and Canada, Merck & Co. holds the rights to the trademark "Merck", while in the rest of the world the company trades under the name MSD (an abbreviation of Merck, Sharp & Dohme) and its legal name says here
2070:
ruled that MSD had breached an agreement with its former parent company and that only Merck of
Darmstadt is entitled to use the Merck name in the United Kingdom. The judge also held that MSD's use of "Merck" as part of branding on its global websites were directed to the UK and infringed Merck's
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in a US$ 41 billion deal. Although Merck & Co. was in reality acquiring
Schering-Plough, the purchase was declared a "reverse merger", in which "Old" Merck & Co. was renamed Merck Sharp & Dohme, and Schering-Plough renamed as "Merck & Co., Inc. The maneuver was an attempt avoid a
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for the isolation of tuberculosis-infected people were a ubiquitous feature of cities in developed countries, with 50% dying within 5 years of admission. Although Merck's agreement with
Rutgers gave it exclusive rights to streptomycin, at Waksman's request the company renegotiated the agreement,
2003:
and the UK National
Osteoporosis Guideline Group recommend alendronate and certain other bisphosphonates as first line treatments for post-menopausal osteopotosis. Long-term treatment with bisphosponates produces anti-fracture and bone mineral density effects that persist for 3–5 years after an
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adopted a new logo and said it will be "much more aggressive" about protecting the brand of "the real Merck". Merck of Darmstadt has initiated litigation against its former subsidiary, Merck & Co. (MSD) of Kenilworth, in several countries over infringing use of the Merck name. In 2016, the
2007:
In December 2013, Merck agreed to pay a total of $ 27.7 million to 1,200 plaintiffs in a class action lawsuit alleging that the company's osteoporosis drug had caused them to develop osteonecrosis of the jaw. Prior to the settlement, Merck had prevailed in 3 of 5 so-called bellwether trials.
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expanded their 18-month-old immuno-oncology collaboration by four years, generating a potential $ 4.4 billion in milestone payments for the Abylnx. The company also announced it would spend $ 95 million up front collaborating with cCAM Biotherapeutics and its early-stage treatment similar to
469:
Merck & Co. was originally established as the American affiliate of Merck Group in 1891. Merck develops and produces medicines, vaccines, biologic therapies and animal health products. It has multiple blockbuster drugs or products each with 2020 revenues including cancer immunotherapy,
1369:(ROR1) in both hematological and solid tumors. VLS-101 is currently Phase I and Phase II clinical trials. The company also announced it would acquire OncoImmune for $ 425 million and its phase 3 candidate, CD24Fc, used in the treatment of patients with severe and critical COVID-19.
1844:
Merck & Co. was one of the first American pharmaceutical companies to offer assistance to those unable to afford its medications, beginning a program in the 1950s. Merck & Co. offers seven patient assistance programs, each with specific eligibility requirements.
2028:
and other health care programs and paid illegal remuneration to health care providers. On February 7, 2008, Merck agreed to pay more than $ 650 million to settle charges that it routinely overbilled Medicaid for its most popular medicines. The settlement was one of the
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1857:, an India-based non-profit research organization dedicated to the development of low-cost vaccines for use in developing countries. Current projects include the development of low cost, thermostable vaccines for the prevention of cholera, rotavirus, and meningitis.
696:, and others. Remicade and other TNF-alpha inhibitors exhibit additive therapeutic effects with methotrexate and improve quality of life. Adverse effects include increased risk of infection and certain cancers. Merck had rights to the drug in certain areas, while
1963:
Merck has refused to consider compensation for Vioxx victims and their families outside the US. This is particularly true in the UK where there are at least 400 victims and the legal protection afforded to the victims and their families is particularly weak.
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in history. The federal government received more than $ 360 million, plus 49 states and Washington, DC, received over $ 290 million. One whistleblower received a $ 68 million reward. Merck made the settlement without an admission of liability or wrongdoing.
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Solomkin, J. S.; Mazuski, J. E.; Bradley, J. S.; Rodvold, K. A.; Goldstein, E. J.; Baron, E. J.; O'Neill, P. J.; Chow, A. W.; Dellinger, E. P.; Eachempati, S. R.; Gorbach, S.; Hilfiker, M.; May, A. K.; Nathens, A. B.; Sawyer, R. G.; Bartlett, J. G. (2010).
730:(MK-3475) as a breakthrough therapy for melanoma treatment. In clinical trials, pembrolizumab provided partial tumor regression in about one quarter of patients, many of whom have not seen further progression of their disease in over 6 months of follow-up.
4241:
716:(raltegravir) is a human immunodeficiency virus integrase inhibitor for the treatment of HIV infection. It is the first anti-HIV compound having this mechanism of action. It is part of one of several first line treatment regimens recommended by the
2491:
Deacon CF, Mannucci E, Ahrén B (August 2012). "Glycaemic efficacy of glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors as add-on therapy to metformin in subjects with type 2 diabetes-a review and meta analysis".
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660:(sitagliptin) is a dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes. In 2013, Januvia was the second largest selling diabetes drug worldwide. Januvia is commonly paired with the generic anti-diabetes drug
1178:
In October 2013, Merck announced it would cut 8,500 jobs in an attempt to cut $ 2.5 billion from its costs by 2015. Combined with 7,500 job cuts announced in 2011 and 2012, the layoffs amounted to 20% of its workforce.
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well as on its social media presence. Further Merck & Co. has also accused the Merck Group of federal trademark dilution, unfair competition, false advertising, deceptive trade practices, breach of contract, and
1278:
In April 2019, the company acquired Immune Design for approximately $ 300 million, gaining access to its immunotherapy programs. It also acquired Antelliq Group for $ 2.4 billion, or $ 3.7 billion including debt.
6456:
Serrano AJ, Begoña L, Anitua E, Cobos R, Orive G (December 2013). "Systematic review and meta-analysis of the efficacy and safety of alendronate and zoledronate for the treatment of postmenopausal osteoporosis".
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968:(founded 1899), creating Merck-Frosst Canada, Inc., as its Canadian subsidiary and pharmaceutical research facility. Merck & Co. closed this facility in July 2010 but remerged in 2011 as Merck Canada.
1828:
Since it was founded in 1957, the Merck Company Foundation has distributed $ 740 million in overall charitable distributions including more than $ 480 million to educational and non-profit organizations.
1092:(VOC) emission pollution in the San Diego area. In 1996 Merck paid $ 1.8 million for polluting the air. New machines were installed to reduce smog emissions by 680,000 lb (310,000 kg) a year.
986:) in 1971. The incidence of rubella-associated birth defects fell from up to 10,000 per year in the U.S. to zero in the aftermath of the rubella vaccine's development. Hilleman also developed the first
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1949:
on September 30. An analysis for the period 1999–2004, based on U.S. Medical Expenditure Survey data, reported that Vioxx was associated with 46,783 heart attacks, and along with the other popular
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of Darmstadt, owns the rights to the "Merck" name. In the United States and Canada, the company trades under the name EMD (an abbreviation of Emanuel Merck, Darmstadt), its legal name here says
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became CEO and Chairman in 1976, serving until 1985. Under his leadership, the company's investment in R&D grew threefold, and Merck became the largest pharmaceutical company in the world.
883:. The government seized 80 percent of the shares owned by the German parent company and sold it. In 1919, George F. Merck (head of the American branch of the Merck family), in partnership with
737:) is an injectable antibiotic, rights to which Merck has owned since 1999. Merck was in a legal dispute with the Taiwanese company Savior Lifetec over their attempt to secure rights to sell a
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returning the rights to the university in exchange for a royalty. The university then set up non-exclusive licenses with seven companies to ensure a reliable supply of the antibiotic.
5684:"SCHEDULE TO TENDER OFFER STATEMENT UNDER SECTION 14(D)(1) OR 13(E)(1) OF THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No. 8) IDENIX PHARMACEUTICALS, INC. IMPERIAL BLUE CORPORATION"
4001:"Diagnosis and Management of Complicated Intra-abdominal Infection in Adults and Children: Guidelines by the Surgical Infection Society and the Infectious Diseases Society of America"
3554:"Early smallpox vaccine manufacturing in the United States: Introduction of the "animal vaccine" in 1870, establishment of "vaccine farms", and the beginnings of the vaccine industry"
3460:"Early smallpox vaccine manufacturing in the United States: Introduction of the "animal vaccine" in 1870, establishment of "vaccine farms", and the beginnings of the vaccine industry"
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merged with Sharp and Dohme, Inc. and brought vaccine technology, including immunization of cavalry horses in World War I and delivery of a diphtheria antitoxin to Merck & Co.
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Gauthier K, Bai A, Perras C, et al. (2012). "Denosumab, Raloxifene, and Zoledronic Acid for the Treatment of Postmenopausal Osteoporosis: Clinical Effectiveness and Harms ".
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In October 2017, the company granted the inaugural Merck-AGITG Clinical Research Fellowship in Gastro-Intestinal (GI) Cancer to David Lau, a professional in Melbourne, Australia.
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Also in June 2020, Merck Animal Health acquired Quantified Ag, a data and analytics company that monitors cattle body temperature and movement in order to detect illness early.
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diuretics were developed by Merck scientists Karl H. Beyer, James M. Sprague, John E. Baer, and Frederick C. Novello and led to the marketing of the first drug of this class,
757:. It is the focus of Merck's Mectizan Donation Program, wherein Merck has donated doses of the drug to treat millions of people in countries such as Yemen and African nations.
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class of antibiotics. Antibiotics of the carbapenem class play an important role in treatment guidelines for certain hospital-acquired and multi-drug resistant infections.
1995:
used for the treatment of post-menopausal osteoporosis and for the prevention of skeletal problems in certain cancers. The American College of Clinical Endocrinology, the
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Vaithianathan R, Hockey PM, Moore TJ, Bates DW (2009). "Iatrogenic effects of COX-2 inhibitors in the US population: findings from the Medical Expenditure Panel Survey".
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vaccines to its portfolio. The combined company kept the trade name Merck in the United States and Canada, and as Merck Sharp & Dohme (MSD) outside North America.
3288:
Antibacterial Agents. Chemistry, Mode of Action, Mechanisms of Resistance, and Clinical Applications. Anderson RJ, Groundwater PJ, Todd A, Worsely AJ. Wiley (2012).
2537:"Incretin treatment and risk of pancreatitis in patients with type 2 diabetes mellitus: systematic review and meta-analysis of randomised and non-randomised studies"
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Eriksen EF, Díez-Pérez A, Boonen S (January 2014). "Update on long-term treatment with bisphosphonates for postmenopausal osteoporosis: a systematic review".
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later the company announced it would acquire IOmet Pharma, with IOmet becoming a wholly owned subsidiary of Merck & Co. The acquisition includes IOmets
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902:-Rosengarten Company, a Philadelphia quinine manufacturer. George Merck remained president and Frederic Rosengarten became chairman of the board. In 1929,
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outside the United States and Canada. It is one of the largest pharmaceutical companies in the world, generally ranking in the global top five by revenue.
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4846:"FDA Accepts Merck's Biologics License Application (BLA) and Grants Priority Review for V920, the Company's Investigational Vaccine for Ebola Zaire Virus"
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1996:
1397:. In October 2021, the company said that the drug reduces the risk of hospitalization or death by around 50% for patients with mild or moderate cases of
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4242:"Statement from Michael Hansen, CEO of Elsevier's Health Sciences Division, Regarding Australia Based Sponsored Journal Practices Between 2000 and 2005"
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In December 2022, the company announced a licensing deal with Kelun-Biotech of China whereby it would expand its early cancer pipeline with a set of
6382:"Diagnosis and management of osteoporosis in postmenopausal women and older men in the UK: National Osteoporosis Guideline Group (NOGG) update 2013"
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5719:"SCHEDULE TO TENDER OFFER STATEMENT UNDER SECTION 14(D)(1) OR 13(E)(1) OF THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No. 3) Immune Design Corp"
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In 1953, Merck & Co. merged with Philadelphia-based Sharp & Dohme, Inc., becoming the largest U.S. drugmaker. Sharp and Dohme had acquired
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4984:"Merck Animal Health Completes Acquisition of Vaki to Further Broaden Its Leadership Position in Aquaculture to Advance Fish Health and Welfare"
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1979:. All its new television pain-advertisements must be vetted by the Food and Drug Administration and changed or delayed upon request until 2018.
1333:
In June 2020, Merck acquired Themis Bioscience, a company focused on vaccines and immune-modulation therapies for infectious diseases including
1199:
and narrowed the company's focus to immunology, vaccines, diabetes, emerging markets and medicines used in hospitals, like certain antibiotics.
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mechanisms, have "commercial effect" in Switzerland and could therefore violate Merck's rights (if any) to the "Merck" brand in Switzerland.
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was reached in 2011, in which Merck agreed to pay $ 500 million. Merck Sharp & Dohme remains a subsidiary of the Merck & Co. parent.
726:(pembrolizumab) is an immune modulator for the treatment of cancer. On September 4, 2014, the US Food and Drug Administration (FDA) approved
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1934:, which were associated with 20,000 hospitalizations and 2000 deaths each year. Vioxx became one of the most prescribed drugs in history.
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E. Merck (and grandson of the founder) joined Weicker in New York. Merck & Co. operated from 1891 to 1917 as the US subsidiary of the
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4903:"Merck Completes Acquisition of Antelliq Corporation to Become Leader in Emerging Digital Technology for Livestock and Companion Animals"
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for $ 680 million. With this purchase, Merck expands its portfolio of oncological drugs. The main positions are HPN328, an activator of
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In November 1993, Merck & Co. acquired Medco Containment Services for $ 6 billion. Merck & Co. spun Medco off ten years later.
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2606:"Systematic review and meta-analysis of the efficacy and safety of existing TNF blocking agents in treatment of rheumatoid arthritis"
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On May 20, 2008, Merck settled for $ 58 million with 30 states alleging that Merck engaged in deceptive marketing tactics to promote
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5769:"Princeton University and The Merck Company Foundation Announce Creation Of New Global Health Scholars Program and Lecture Series"
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Schrick, Livia; Tausch, Simon H.; Dabrowski, P. Wojciech; Damaso, Clarissa R.; Esparza, José; Nitsche, Andreas (12 October 2017).
6603:"Merck Resolves Federal and State Investigations Related to Certain Past Pricing And Certain Past Sales and Marketing Activities"
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4521:"Merck Acquires OncoEthix, a Privately Held Oncology Company Developing Novel BET Inhibitors for Hematological and Solid Cancers"
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In April 2021, Merck acquired Pandion Therapeutics for $ 1.85 billion, expanding its offering in treating autoimmune diseases.
1379:, where she participated in a tabletop exercise simulating the public health response to the release of a weaponized strain of
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Between 2010 and 2015, the company cut around 36,450 jobs. During that time, the company sold its consumer health business to
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Kinch MS, Haynesworth A, Kinch SL, Hoyer D (August 2014). "An overview of FDA-approved new molecular entities: 1827–2013".
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under the Breakthrough Therapy Designation for an investigational vaccine, called V920, to fight the Zaire strain of the
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use when compared with naproxen. Merck adjusted the labeling of Vioxx to reflect possible cardiovascular risks in 2002.
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6302:"Management of osteoporosis in postmenopausal women: 2010 position statement of The North American Menopause Society"
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Merck for Mothers is Merck's global initiative to help create a world where no woman has to die while giving life.
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3218:"F. Rosengarten of Merck Co. Dies: Retired Chairman of Makers of Pharmaceuticals Headed Hospital in Philadelphia"
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843:. In 1827, Merck Group evolved from a pharmacy to a drug manufacturer company with the commercial manufacture of
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3314:. A Witness Seminar held at the Wellcome Institute for the History of Medicine, London. London: Wellcome Trust.
777:, a series of medical reference books for physicians, nurses, technicians, and veterinarians. These include the
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initial 3–5 years of treatment. Alendronate reduces the risk of hip, vertebral, and wrist fractures by 35-39%.
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in 1992. "MERCK" trade name is used in U.S. and Canada (top); outside these countries "MSD" is used (bottom).
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2341:"Merck Surpasses Expectations: Invested more than €300 million in New Life Science Research Center, Germany"
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In May 2019, Merck announced it would acquire Peloton Therapeutics, developer of a HIF-2alpha inhibitor for
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In September 2017, the company announced it would acquire Rigontec, developer of a candidate to target the
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In November 2020, Merck announced it would acquire VelosBio for $ 2.75 billion, developer of VLS-101, an
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In April 2017, Merck Animal Health acquired Vallée S.A., a Brazilian animal health product manufacturer.
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In November 2019, the company acquired Calporta, which focused on Parkinsons and Alzheimers treatments.
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began in 2000 when allegations were brought in two separate lawsuits filed by whistleblowers under the
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In December 2014, the company acquired Swiss biotechnology company OncoEthix for up to $ 375 million.
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In 2007, Merck paid $ 2.3 billion to settle allegations of offshore tax fraud between 1993 and 2001.
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In July 2021, Robert M. Davis became CEO, succeeding Kenneth Frazier, who became executive chairman.
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6585:"Merck to Pay More than $ 650 Million to Resolve Claims of Fraudulent Price Reporting and Kickbacks"
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5396:"Merck says its new Covid pill reduces the risk of hospitalization, death by half for some patients"
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Kingston W (July 2004). "Streptomycin, Schatz v. Waksman, and the balance of credit for discovery".
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In July 2016, the company acquired Afferent Pharmaceuticals, developer of a candidate used to block
789:, a compendium of chemical compounds, was published by Merck & Co. until it was acquired by the
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Thereafter, studies by Merck and by others found an increased risk of heart attack associated with
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Keytruda. Merck & Co. will bring in CM-24, an antibody designed to block the immune checkpoint
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succeeded his father George F. Merck as president. In 1927, the corporation merged with the Powers-
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In March 2020, Merck was one of ten companies recognised at the inaugural Manufacturing Awards by
458:, founded in Germany in 1668, of which it was once the American arm. The company does business as
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7990:
7711:
7701:
7696:
7554:
7494:
7302:
6985:
4926:
4373:
4168:
3945:
3155:
2669:"Merck and Johnson & Johnson Reach Agreement on Distribution Rights for Remicade and Simponi"
2243:
2136:
1452:
1389:
In June 2021, the U.S. government agreed to spend $ 1.2 billion to purchase 1.7 million doses of
1362:
1135:
242:
139:
104:
7424:
4922:"Peloton Therapeutics' $ 2.2 billion deal with Merck took root with an idea for clinical trials"
4757:"Merck to Acquire Rigontec, RIG-I Therapeutics Pioneer, Advancing Leadership in Immuno-Oncology"
4260:
8095:
8065:
8015:
7970:
7818:
7509:
7377:
7041:
6584:
6172:
4199:
1615:
1486:
1430:
1203:
689:
631:
6733:"Exclusive: Merck anti-baldness drug Propecia has long trail of suicide reports, records show"
5988:"Toward an epidemiology of gastropathy associated with nonsteroidal antiinflammatory drug use"
4118:
1540:(Acq 1965, restructured into Merck-Frosst Canada, Inc, restructured into Merck Canada in 2011)
1375:
In March 2021, Merck Head of Corporate Affairs Petra Wicklandt represented the company at the
8301:
8170:
7975:
7793:
7758:
7604:
7584:
7371:
7198:
7092:
7046:
6513:
6227:
5641:"Merck, Johnson & Johnson Announce Acquisitions to Bolster Respective Oncology Pipelines"
5057:
3689:
3430:
Networks of Innovation: Vaccine Development at Merck, Sharp and Dohme, and Mulford, 1895–1995
2063:
1854:
1833:
1490:
950:
903:
836:
741:
version in the United States. Savior has since obtained approval to market generic ertapenem.
267:
6147:
5273:"Strengthening Global Systems to Prevent and Respond to High-Consequence Biological Threats"
4281:
4198:
4091:
2880:
2741:
8341:
8311:
8130:
8105:
8055:
8050:
8030:
7980:
7913:
7903:
7773:
7748:
7656:
7651:
7619:
7549:
7519:
7405:
6938:
6276:
5825:"Patient Assistance – Available Prescription Assistance Programs From Merck & Co."
5463:
4431:
3881:
3782:
3623:
2619:
2404:
1293:
In June 2019, Merck announced it would acquire Tilos Therapeutics for up to $ 773 million.
1287:
1183:
1162:
1067:
1044:
707:
681:
544:
306:
6808:
6148:
4282:
3663:
1237:
receptors, for approximately $ 1 billion, plus up to $ 750 million in milestone payments.
8:
8371:
8291:
8155:
8120:
8110:
8035:
8020:
7743:
7738:
7479:
7469:
7339:
6569:
5939:
3131:"In another round of Merck vs. Merck, Germany-based Merck KGaA notches a win in the U.K."
2947:
2918:
2180:
1445:
987:
627:
287:
3885:
3757:
2623:
2586:
2083:" made by the Merck Group and three-times the damage, plus additional punitive damages.
1455:; this follows an earlier agreement between the two companies to co-develop such drugs.
700:
had rights in other areas; in 2017, Merck announced a biosimilar to Remicade, Renflexis.
8386:
8080:
7893:
7863:
7813:
7579:
7564:
7223:
7147:
6482:
6329:
6282:
6177:
6154:
6122:
6056:
4288:
4205:
3902:
3869:
3787:
3580:
3553:
3488:
3459:
3271:
2887:
2846:
2642:
2605:
2563:
2536:
2517:
2473:
2362:
2128:
2052:
Merck Sharp & Dohme LLC., a subsidiary of Merck & Co., Inc. Kenilworth, NJ, USA
1620:
1412:
1267:
In 2018, Merck began the submission process for a Biologics License Application to the
918:
706:(recombinant human papilloma virus vaccine) is a vaccine against multiple serotypes of
685:
540:
496:
489:
451:
208:
6004:
5987:
2942:
1832:
On December 7, 2012, the foundation announced that it was ending its donations to the
8060:
8025:
7514:
7282:
6990:
6501:
6474:
6438:
6403:
6362:
6321:
6114:
6110:
6061:
6009:
4448:
4226:
4173:
4163:
4098:
4049:
4022:
3907:
3792:
3718:
3585:
3552:
Esparza, José; Lederman, Seth; Nitsche, Andreas; Damaso, Clarissa R. (19 June 2020).
3534:
3493:
3464:
3438:
3358:
3315:
3308:
3289:
3263:
3091:"With Merck & Co. Offering, Goldman Sachs Emerges from the Shadow of World War I"
3056:
3031:
3006:
2922:
2851:
2647:
2568:
2509:
2505:
2477:
2465:
2461:
2248:
1927:
1434:
1138:
991:
899:
773:
635:
572:
277:
6486:
6398:
6381:
6126:
5480:"Merck's Ken Frazier, one of just 4 Black CEOs in the Fortune 500, is stepping down"
5375:"Merck signs $ 1.2 billion deal with US government for experimental COVID treatment"
3275:
2521:
2086:
In April 2020, in the course of litigation of Merck against MSD in Switzerland, the
1062:. During the late 1980s and 1990s, the company also established joint ventures with
599:
that had $ 1.1 billion in 2020 revenue. Other major products by the company include
8440:
8286:
8266:
8261:
7788:
7726:
7706:
7661:
7646:
7589:
7036:
6995:
6466:
6430:
6393:
6333:
6313:
6287:
6106:
5999:
4440:
4148:
4123:
4012:
3897:
3889:
3575:
3565:
3524:
3483:
3473:
3402:
3376:
3348:
3255:
2970:
2892:
2637:
2627:
2558:
2550:
2501:
2457:
2021:
2008:
Approximately 4000 cases still await adjudication or settlement as of August 2014.
1969:
1923:
1778:
1422:
1416:
1355:
971:
693:
528:
368:
3570:
3478:
3458:
Esparza, José; Lederman, Seth; Nitsche, Andreas; Damaso, Clarissa R. (June 2020).
3195:
1926:. Such compounds were expected to cause less gastrointestinal bleeding than older
1299:
In December 2019, Merck Animal Health acquired Vaki, an aquaculture company, from
1024:
8428:
8135:
8045:
8040:
7681:
7629:
7599:
7382:
7183:
7072:
7051:
6470:
6317:
5986:
Fries JF, Miller SR, Spitz PW, Williams CA, Hubert HB, Bloch DA (February 1989).
5831:
5813:
5484:
4444:
3608:
2632:
2604:
Aaltonen KJ, Virkki LM, Malmivaara A, Konttinen YT, Nordström DC, Blom M (2012).
2192:
2173:
1950:
1555:
1444:, a livestock management company for an undisclosed sum, incorporating it within
1172:
1153:
1040:
979:
895:
888:
785:
754:
697:
560:
6912:
6665:"Merck KGaA, Darmstadt, Germany Announces Favorable UK Court Ruling on Name Use"
6259:
4326:"Merck Legally Changed Its Name 3 Times to Achieve Reverse Merger With Schering"
3925:
2358:
1121:
From 2002 through 2005, the Australian affiliate of Merck paid publishing house
50:
8531:
8346:
7965:
7332:
7238:
6980:
6760:"Investigation Finds Merck's Anti-Baldness Drug Long Linked to Suicide Reports"
6649:
6434:
6245:
5144:"Merck to buy $ 1 billion stake in Seattle Genetics, co-develop cancer therapy"
4409:
2966:
2176:
2090:
ruled that MSD's use of the "Merck" brand in its global websites could, absent
2076:
2067:
1992:
1945:
1882:
1241:
1082:
1036:
961:
943:
914:
855:, used to treat sinus problems and to add to beverages to boost energy levels.
647:
447:
257:
87:
6785:"Merck & Co. Slapped With Wrongful Death Suit Over Popular Hair Loss Drug"
5670:"Merck Snaps up Small Startup in $ 208M Deal, Seeks to Improve Safety of ADCs"
4579:"Ablynx, Merck & Co. Ink $ 4B+ Expansion of Immuno-Oncology Collaboration"
1103:
680:
and used for the treatment of a wide range of autoimmune disorders, including
8450:
8351:
8316:
8145:
7943:
7845:
7753:
7188:
7102:
7015:
6606:
6143:
6065:
6045:
5521:
5503:
5313:
5257:
5129:
5111:
5043:
5005:
4987:
4966:
4906:
4888:
4849:
4830:
4760:
4724:
4601:
4564:
4524:
4470:
4177:
4053:
4042:"Medicine, Management, and Mergers: An Interview with Merck's P. Roy Vagelos"
3796:
3094:
2855:
2672:
2376:
2270:
2252:
2169:
1516:, later Nationalised by the US government in 1917 during the first World War)
1312:
1055:
998:
975:
884:
876:
727:
536:
524:
507:
95:
6930:
6348:
6301:
5912:"Merck & Co & UNICEF USA's Partnership to Save and Protect Children"
5852:
4671:"Acquisitions, Divestitures, Research Collaborations and License Agreements"
3353:
3336:
2445:
1885:, also known as river blindness, primarily in Africa. Up to that point, the
1157:"change-of-control" in order to preserve Schering-Plough's rights to market
7923:
7363:
7355:
7228:
7127:
7010:
7000:
6907:
6505:
6478:
6442:
6407:
6366:
6325:
6118:
5791:
5169:"Merck to buy $ 1 bln stake in Seattle Genetics, co-develop cancer therapy"
4801:"Doctor David Lau reflects on the Merck-AGITG Clinical Research Fellowship"
4452:
4026:
3911:
3648:
3589:
3538:
3497:
3267:
3259:
2651:
2572:
2513:
2469:
2184:
2091:
1890:
1481:
that is being researched to treat advanced cancer patients associated with
1390:
922:
910:
832:
760:
738:
282:
262:
76:
34:(Merck KGaA), a distinct but historically related company based in Germany.
6541:"Merck agrees to proposed $ 27.7 million settlement over Fosamax lawsuits"
6013:
5348:"Merck Snaps Up Autoimmune-Focused Pandion in Massive $ 1.85 Billion Deal"
3840:
3362:
1189:
In August 2014, Merck acquired Idenix Pharmaceuticals for $ 3.85 billion.
8115:
7798:
7666:
7398:
7288:
7203:
7157:
7152:
7137:
7132:
7122:
7097:
6902:
5876:"Merck JV plans to show up J&J, Sanofi with low-cost cholera vaccine"
5421:
4635:"Merck & Co. Launches Up-to-$ 280M Cancer Collaboration with Complix"
3529:
3512:
2290:
2115:
2058:
2043:
1988:
1513:
1459:
1426:
1272:
1059:
983:
872:
860:
828:
821:
807:
604:
568:
552:
482:
455:
164:
31:
5705:"Merck & Co., Inc. – Financials – SEC Filings – SEC Filings Details"
5438:"Kenneth Frazier stepping down as Merck CEO, becomes executive chairman"
1182:
By 2014, research performed at Merck has led to U.S. FDA approval of 63
1125:
an undisclosed amount to produce eight issues of a medical journal, the
710:(HPV), which is responsible for most cases of cervical cancer worldwide.
650:
in adults that generated $ 725 million in 2020 revenue for the company.
8376:
8366:
8321:
8276:
8175:
7803:
7534:
7218:
7213:
7208:
7167:
7162:
7117:
7077:
7056:
6048:; Harris, Gardiner; Meier, Barry; Pollack, Andrew (November 14, 2004).
5189:"Merck Snaps up VelosBio and its ROR1 Inhibitor in $ 2.75 Billion Deal"
4689:"Merck & Co. to Acquire Afferent Pharmaceuticals for Up to $ 1.25B"
3959:"Japanese microbiologist Satoshi Omura shares Nobel Prize for medicine"
3893:
3337:"Chlorothiazide. How the thiazides evolved as antihypertensive therapy"
1944:
On September 23, 2004, Merck received information about results from a
1703:
1261:
1078:
1032:
1028:
1005:
926:
827:
Merck & Co. traces its origins to its former German parent company
753:(ivermectin) is an anti-parasitic medicine traditionally used to treat
646:), a medication for the maintenance treatment of BRCA-mutated advanced
584:
576:
475:
334:
125:
119:
6922:
4865:"Merck to buy immunotherapy developer Immune Design for $ 300 million"
2554:
1039:
in 1987–88 with the name Mectizan; today the compound is used against
108:
8396:
8361:
8326:
8125:
7995:
7768:
7733:
7594:
7569:
7193:
7142:
7107:
7087:
7082:
5968:
5627:"Merck to Buy Cancer Immunotherapy Biotech Harpoon for $ 680 Million"
5442:
5417:"Merck's new CEO Robert Davis begins, after Ken Frazier's retirement"
5328:"Merck to buy drug developer Pandion Therapeutics for $ 1.85 billion"
4739:"Merck to Acquire Rigontec, Expanding Cancer Immunotherapy Franchise"
4143:
1919:
1915:
1894:
1380:
1348:
840:
817:
734:
713:
677:
661:
620:
5254:"Merck Animal Health Completes Acquisition of Poultry Sense Limited"
5084:"Merck to buy Austrian vaccine maker as it jumps into COVID-19 race"
4617:"Quartet, Merck Partner on Pain Treatments in Up-to-$ 595M Alliance"
2963:"Opioid epidemic shares chilling similarities with past drug crises"
1393:, a Merck product, if it were to be approved by regulators to treat
875:, due to its German connections, Merck & Co. was the subject of
8005:
8000:
7883:
7873:
7544:
7233:
7112:
5972:
5897:
4414:
4330:
4245:
4074:"U.S. SETTLES $ 1.8 MILLION POLLUTION CASE WITH MERCK AND MONSANTO"
4017:
4000:
2610:
2025:
1953:
1931:
1881:
to "all that need it for as long as needed" in an effort to combat
1878:
1398:
1394:
1372:
In February 2021, Merck Animal Health acquired PrognostiX Poultry.
1334:
1158:
1122:
1074:
965:
954:
939:
844:
764:
750:
723:
703:
676:(infliximab) is a monoclonal antibody directed toward the cytokine
673:
643:
612:
564:
516:
234:
55:
The current Merck & Co. logo, designed by Steff Geissbuhler of
8243:
6200:
Vioxx MDL Plaintiffs' Steering Committee Official Vioxx Settlement
5787:"Boy Scouts of America: Merck pulls funding in protest at gay ban"
5271:
Yassif, Jaime; O'Prey, Kevin; Isaac, Christopher (November 2021).
2446:"Sitagliptin in the treatment of type 2 diabetes: a meta-analysis"
812:
8401:
8391:
8160:
8010:
7933:
7853:
7823:
7721:
7686:
7624:
7539:
7499:
7484:
7454:
6737:
6626:
6545:
6262:
5586:
5332:
5208:
5173:
5148:
5088:
4947:
4869:
4309:
3870:"Ivermectin, 'Wonder drug' from Japan: The human use perspective"
3180:
3053:
The Merck Druggernaut: The Inside Story of a Pharmaceutical Giant
3030:(2nd ed.). Los Angeles, CA: SAGE Publications. p. 758.
2745:
2603:
2541:
2327:"Pharma 50: The 50 largest pharmaceutical companies in the world"
2286:"Merck names Treasurer Caroline Litchfield CFO effective April 1"
2111:
1478:
1300:
1264:, an Australian viral cancer drug company, for AUD$ 502 million.
1215:
1048:
852:
847:. Merck perfected the chemical process of deriving morphine from
744:
657:
520:
272:
4963:"COI Pharmaceuticals Announces Acquisition of Calporta by Merck"
4776:"Dr David Lau receives Merck-AGITG Clinical Research Fellowship"
8281:
8165:
8100:
8090:
7985:
7716:
7529:
7474:
7324:
5916:
5551:"Merck builds out cancer drug pipeline with Kelun-Biotech deal"
5204:"Merck adds experimental COVID-19 therapy with OncoImmune deal"
4653:"Merck & Co. Acquires Cancer Immunotherapy Developer IOmet"
2381:
1874:
1338:
1210:
1063:
1013:
5228:"Merck Bolsters COVID-19 Pipeline with OncoImmune Acquisition"
4597:"Merck signs a $ 605M deal to bulk up in cancer immunotherapy"
3002:
The History of Foreign Investment in the United States to 1914
1358:
common stock, and agreed to co-develop ladiratuzumab vedotin.
495:, both based on 2021 revenues. In 2023, the company’s seat in
8336:
8296:
8271:
8180:
8150:
8085:
7574:
7504:
7489:
6831:
6096:
6051:"Despite Warnings, Drug Giant Took Long Path to Vioxx Recall"
5806:"Merck to Create New Patient Assistance Program for Vaccines"
5108:"Merck Animal Health Completes Acquisition of Quantified Ag®"
3997:
3817:"20th Century Leaders - Leadership - Harvard Business School"
3176:"Fight over Merck name sees German firm win in British court"
2911:
Voinea, Cosmina Lelia; Kranenburg, Hans Van (July 14, 2017).
2157:
1976:
1938:
1466:
1441:
1234:
1206:
for $ 102 per share in cash or about $ 9.5 billion in total.
1196:
1142:
848:
667:
624:
351:
44:
6380:
Compston J, Bowring C, Cooper A, et al. (August 2013).
5582:"Merck to buy Prometheus Biosciences for about $ 11 billion"
3551:
3510:
3457:
2267:"Merck Appoints Caroline Litchfield Chief Financial Officer"
1922:. Vioxx was designed as a selective inhibitor of the enzyme
1141:
retired following Merck's voluntary worldwide withdrawal of
7960:
6705:
6701:"Merck Agrees to Settle $ 2.3 Billion Tax Dispute with IRS"
5602:"Owkin and MSD join forces on AI-powered digital pathology"
5400:
4543:"Merck tallies 36,000 job cuts in 5 years of restructuring"
4346:"Merck, Johnson & Johnson reach Remicade, Simponi deal"
3310:
Post-Penicillin Antibiotics: From Acceptance to Resistance?
2803:"Merck sues Taiwan company over generic antibiotic product"
2691:"Merck, Samsung Bioepis Launch Remicade Biosimilar in U.S."
1482:
1366:
113:
8482:
Multinational companies headquartered in the United States
6644:"A Tale of Two Mercks as Protesters Take On Wrong Company"
6044:
4721:"Merck Animal Health Completes Acquisition of Vallée S.A."
4428:
4368:"Merck Chairman Clark To Retire; CEO Frazier to Take Over"
2024:. They alleged that Merck failed to pay proper rebates to
1440:
In September 2022, the company announced it would acquire
1152:
In November 2009, Merck & Co. completed a merger with
982:
in 1969, and the first trivalent measles, mumps, rubella (
767:, developed in partnership with Ridgeback Biotherapeutics.
8331:
6641:
Connolly, Allison; Kitamura, Makiko (February 10, 2014).
5500:"Merck Announces Completion of Organon & Co. Spinoff"
4943:"Merck to buy Tilos Therapeutics for up to $ 773 million"
4394:
4265:
2760:"Merck Melanoma Drug Is First PD-1 Inhibitor OK'd by FDA"
2042:
In 191 of 193 countries, the original Merck company, the
1171:
retired as CEO and company president in October 2011 and
913:
was discovered during a Merck-funded research program in
511:
Gardasil 9 in French packaging (showing the MSD branding)
471:
6891:
6455:
5985:
5126:"Merck Animal Health Completes Acquisition of IdentiGEN"
1473:
In January 2024, the company announced it would acquire
1465:
In December 2023, Merck announced it had partnered with
8256:
6420:
4885:"Merck Completes Tender Offer to Acquire Immune Design"
3427:
Galambos, Louis; Sewell, Jane Eliot (August 13, 1997).
2986:
Practical Druggist and Pharmaceutical Review of Reviews
2037:
1066:
to access research and development expertise, and with
4139:"Merck finally spins off Medco Health to shareholders"
3513:"An Early American Smallpox Vaccine Based on Horsepox"
2943:"The history of heroin: From King Tut to cough remedy"
1088:
In 1991, Merck's Kelco subsidiary was responsible for
8412:
6379:
6028:"Shocker! Is Vioxx Coming Back... as an Orphan Drug?"
5953:
Onchocerciasis: Africa's victory over river blindness
5310:"Merck Completes Acquisition of Pandion Therapeutics"
5270:
4707:"Merck looks for a return on its Lynparza investment"
4303:
Berkrot, Bill; Pierson, Ransdell (November 3, 2009).
4200:"Merck paid for medical 'journal' without disclosure"
2842:"A Pill to Treat Covid-19? The U.S. Is Betting on It"
2306:"The top 10 most profitable pharma companies in 2021"
1311:
In January 2020, Merck acquired ArQule, developer of
1085:
became CEO and Chairman that year, succeeding Horan.
718:
United States Department of Health and Human Services
6173:"Merck Agrees to Pay $ 4.85 Billion in Vioxx Claims"
3150:"Germany's Merck KGaA Wins Battle Over Name in U.K."
2218:"Merck & Co., Inc. 2023 Form 10-K Annual Report"
1421:
In September 2021, Merck announced it would acquire
997:
The company was incorporated in New Jersey in 1970.
531:
or products, each with over $ 1 billion in revenue:
6622:"Merck reaches settlement in Medicaid rebate probe"
6565:"Merck to Pay $ 650 Million In Medicaid Settlement"
3981:"Joint Ventures and Other Equity Method Affiliates"
3644:"Montreal plant among 17 closed by drugmaker Merck"
2490:
1997:
American College of Obstetricians and Gynecologists
1893:to lower the population of its primary vector, the
1035:use in 1981, and later put it to human use against
634:that had $ 838 million in 2020 revenue; RotaTeq, a
571:that had $ 3.9 billion in 2020 revenue; Varivax, a
407:
6642:
6275:
6241:"Vioxx maker Merck and Co drew up doctor hit list"
6049:
4826:"Merck & Co. completes Viralytics acquisition"
4366:
3307:
3148:
3055:. Hoboken, NJ: John Wiley & Sons. p. 23.
2725:"HIGHLIGHTS OF PRESCRIBING INFORMATION: ISENTRESS"
2236:
1968:intimidation of researchers and infringement upon
653:Details of Merck's major products are as follows:
6499:
6349:"ACOG releases practice bulletin on osteoporosis"
5955:, Africa Recovery, Vol. 17 No. 1 (May 2003), p. 6
4283:"Merck to Buy Schering-Plough for $ 41.1 Billion"
2778:"HIGHLIGHTS OF PRESCRIBING INFORMATION: Keytruda"
2708:"HIGHLIGHTS OF PRESCRIBING INFORMATION: GARDASIL"
2156:Merck was a Conference Supporter for the Virtual
1354:In September 2020, Merck acquired $ 1 billion of
417:
8448:
6640:
6260:Arizona gets $ 2.3 Million from Vioxx Settlement
4561:"Merck Completes Tender Offer to Acquire Cubist"
4467:"Merck Completes Tender Offer to Acquire Idenix"
3754:"Chickenpox: Attenuated Strain Licensed in U.S."
3198:. Rahway, New Jersey: Merck & Co., Inc. 1891
2910:
2427:"The top 10 best-selling diabetes drugs of 2013"
1458:In April 2023, Merck announced it would acquire
8527:Companies listed on the New York Stock Exchange
4305:"Merck, Schering-Plough set to complete merger"
4119:"Merck Completes $ 6 Billion Merger With Medco"
3783:"John Horan, Former Chief of Merck, Dies at 90"
2988:. New York: Lillard & Company. p. 375.
1128:Australasian Journal of Bone and Joint Medicine
1070:to sell over-the-counter consumer medications.
7176:
5845:"Environmental, Social & Governance (ESG)"
4302:
3426:
3305:
2823:"LABEL: ERTAPENEM- ertapenem sodium injection"
2663:
2661:
1853:Merck and the Wellcome trust jointly fund the
1839:
1836:citing its discrimination against gay people.
1485:expression (delta-like ligand 3), an inherent
921:. It became the first effective treatment for
783:, the world's best-selling medical reference.
470:anti-diabetic medication and vaccines against
8517:Companies in the Dow Jones Industrial Average
8467:Pharmaceutical companies of the United States
8229:
7456:Pharmaceutical companies of the United States
7440:
7340:
6960:
6946:
6813:United States Environmental Protection Agency
5201:
4536:
4534:
4164:"Gates Foundation Buys Stakes in Drug Makers"
4078:United States Environmental Protection Agency
2133:United States Environmental Protection Agency
1900:
1347:In August 2020, Merck Animal Health acquired
27:American multinational pharmaceutical company
8507:Pharmaceutical companies established in 1891
8487:Pharmaceutical companies based in New Jersey
8462:Biotechnology companies of the United States
7844:
5963:
5961:
4863:Babu, Aakash Jagadeesh (February 21, 2019).
4162:Bank, David; Buckman, Rebecca (2002-05-17).
2906:
2904:
2902:
2443:
2238:"Merck Names 30-Year Company Veteran as CFO"
2146:
1868:
1351:, engaged in DNA-based animal traceability.
1328:New Jersey Business and Industry Association
974:, a scientist at Merck, developed the first
638:that had $ 797 million in 2020 revenue; and
591:that had $ 1.2 billion in 2020 revenue; and
8522:Companies in the Dow Jones Global Titans 50
8492:Companies based in Union County, New Jersey
6277:"Merck Agrees to Settlement Over Vioxx Ads"
4161:
3306:Tansey, E.M.; Reynolds, L.A., eds. (2000).
3028:The SAGE Encyclopedia of Cancer and Society
2875:
2873:
2871:
2658:
2535:Li L, Shen J, Bala MM, et al. (2014).
2160:Asia Pacific conference in September 2020.
2122:
2081:all monetary gains, profits, and advantages
1914:(FDA) approved Vioxx (known generically as
1823:
8236:
8222:
7447:
7433:
7347:
7333:
6953:
6939:
6167:
6165:
6138:
6136:
5928:
5548:
4531:
4093:"Merck & Co. completes Medco purchase"
3939:
3874:Proceedings of the Japan Academy, Series B
3867:
3863:
3861:
3245:
3239:
3106:
3104:
3077:"This month in 1917: A tale of two Mercks"
2587:"AHA: IMPROVE-IT Proves Ezetimibe Benefit"
2534:
2444:Zhan M, Xu T, Wu F, Tang Y (August 2012).
1889:had fought the disease through the use of
801:
65:
8472:Veterinary companies of the United States
6397:
6003:
5958:
5372:
5082:Erman, Julie Steenhuysen (May 26, 2020).
4798:
4258:
4016:
3901:
3579:
3569:
3528:
3487:
3477:
3352:
3050:
2899:
2796:
2794:
2641:
2631:
2562:
2234:
1512:(Founded in 1891 as the US subsidiary of
1425:for $ 11.5 billion, gaining control over
579:that had $ 1.9 billion in 2020 revenues;
547:that had $ 14.3 billion in 2020 revenue;
6558:
6556:
6149:"Courts Reject Two Major Vioxx Verdicts"
6142:
5904:
5459:"Merck CEO stepping down at end of June"
5456:
3918:
3400:
3170:
3168:
3166:
2868:
1956:, an estimated 26,603 deaths from both.
1848:
1102:
811:
615:that had $ 857 million in 2020 revenue;
563:that had $ 5.3 billion in 2020 revenue;
506:
6683:"Judgment 4A_335/2019 of 29 April 2020"
6562:
6162:
6133:
5946:
5873:
5726:U.S. Securities and Exchange Commission
5691:U.S. Securities and Exchange Commission
5518:"Merck to Acquire Acceleron Pharma Inc"
5414:
5040:"Merck Completes Acquisition of Themis"
5002:"Merck Completes Acquisition of ArQule"
4940:
4675:U.S. Securities and Exchange Commission
4503:"Merck Buys OncoEthix for up to $ 375M"
4358:
4323:
4117:JOHNSON, LINDA A. (November 18, 1993).
4116:
4039:
3985:U.S. Securities and Exchange Commission
3858:
3101:
3025:
2998:
2983:
2800:
2283:
2222:U.S. Securities and Exchange Commission
2011:
481:The company is ranked 71st on the 2022
14:
8502:American companies established in 1891
8449:
6727:
6725:
6723:
6619:
5536:"Merck Animal Health to Acquire Vence"
5393:
4773:
4540:
4279:
4234:
4213:
4196:
3740:"Abnormal Development – Rubella Virus"
2839:
2791:
2424:
1496:
1367:Tyrosine kinase-like orphan receptor 1
8217:
7428:
7328:
7276:Merck Manual of Diagnosis and Therapy
6934:
6553:
6212:
6193:"Description of Settlement Agreement"
5784:
5579:
5561:from the original on 22 December 2022
5478:Brown, Courtenay (February 4, 2021).
5477:
5457:Williams, Jordan (February 4, 2021).
5435:
5202:O'Donnell, Carl (November 23, 2020).
5081:
4920:Repko, Melissa (September 20, 2019).
4919:
4387:
4364:
4190:
3780:
3776:
3774:
3715:College of Physicians of Philadelphia
3711:"1971-MMR Combination Vaccine Debuts"
3686:College of Physicians of Philadelphia
3668:College of Physicians of Philadelphia
3334:
3163:
3128:
2212:
2210:
2208:
2163:
1149:was named CEO and company president.
1073:In 1985, Merck received approval for
780:Merck Manual of Diagnosis and Therapy
527:products. In 2020, the company had 6
6687:Federal Supreme Court of Switzerland
6563:Johnson, Carrie (February 8, 2008).
6346:
6238:
5785:Rushe, Dominic (December 10, 2012).
5549:Pagliarulo, Ned (22 December 2022).
4862:
4219:
4066:
3868:Crump, Andy; Omura, Satoshi (2011).
3299:
3112:"Legal Wrangle Pits Merck vs. Merck"
2377:"Forbes Global 2000: Merck & Co"
2114:revealed that Merck's baldness drug
2088:Federal Supreme Court of Switzerland
1873:In 1987, Merck began a program with
1860:
1319:(BTK) inhibitor, for $ 2.7 billion.
1145:. Former president of manufacturing
1004:In 1979, Merck scientists developed
6898:Business data for Merck & Co.:
6720:
6589:United States Department of Justice
5924:from the original on 26 April 2012.
5740:"Foundation – Merck Responsibility"
5166:
5152:. 14 September 2020. Archived from
4823:
4799:Institute, GI Cancer (2020-09-09).
3129:Bulik, Beth Snyder (June 1, 2020).
2018:United States Department of Justice
1230:(TDO), and dual-acting inhibitors.
1116:Bill & Melinda Gates Foundation
597:pneumococcal polysaccharide vaccine
24:
7734:Pharmaceutical Product Development
6809:"Merck & Co., Inc. Settlement"
5436:Bomey, Nathan (February 4, 2021).
5167:Roy, Trisha (September 14, 2020).
4365:Rubin, Ben Fox (October 6, 2011).
4324:Edwards, Jim (November 10, 2009).
4280:Singer, Natasha (March 10, 2009).
4106:from the original on May 29, 2019.
3771:
2450:Journal of Evidence-Based Medicine
2235:Trentmann, Nina (March 24, 2021).
2205:
2168:Merck is a contributing member of
2031:largest pharmaceutical settlements
1411:In July 2021, Merck completed the
960:In 1965, Merck & Co. acquired
881:Trading with the Enemy Act of 1917
866:
747:is an antiseptic medicated powder.
25:
8548:
8512:1891 establishments in New Jersey
6883:
5394:Taylor, Chloe (October 1, 2021).
4941:Mathias, Tamara (June 10, 2019).
4541:Staton, Tracy (August 13, 2015).
4259:SILBERNER, JOANNE (May 6, 2005).
3961:. The Japan Times. 5 October 2015
3146:
2801:Jeffrey, Jeff (August 25, 2015).
2284:Linnane, Ciara (March 24, 2021).
1912:U.S. Food and Drug Administration
8434:
8422:
8203:List of pharmaceutical companies
7354:
6858:"Current Organizational Members"
6850:
6819:
6801:
6777:
6752:
6693:
6675:
6657:
6634:
6620:Hurdle, Jon (February 7, 2008).
6613:
6595:
6577:
6533:
6493:
6449:
6414:
6373:
6340:
6294:
6268:
6253:
6232:
6206:
6185:
6111:10.2165/00002018-200932040-00007
6090:
6072:
6038:
6020:
5979:
5890:
5886:from the original on 2015-02-07.
5874:Helfand, Carly (June 20, 2014).
5867:
5837:
5818:
5799:
5778:
5761:
5732:
5711:
5697:
5676:
5662:
5647:. 9 January 2024. Archived from
5633:
5619:
5594:
5580:Erman, Michael (17 April 2023).
5573:
5542:
5528:
5510:
5492:
5471:
5450:
5429:
5408:
5387:
5373:Schumaker, Erin (June 9, 2021).
5366:
5340:
5320:
5302:
5264:
5246:
5220:
5195:
5181:
5160:
5136:
5118:
5100:
5075:
5050:
5032:
5020:"Inaugural Manufacturing Awards"
5012:
4994:
4976:
4955:
4934:
4913:
4895:
4877:
4856:
4838:
4817:
4792:
4767:
4749:
4731:
4713:
4699:
4681:
4388:Smith, Aaron (October 1, 2013).
4261:"Merck CEO Gilmartin Steps Down"
4197:Singer, Natasha (May 13, 2009).
4040:Nichols, Nancy A. (1994-11-01).
2675:. April 15, 2011. Archived from
2506:10.1111/j.1463-1326.2012.01603.x
2462:10.1111/j.1756-5391.2012.01189.x
2001:North American Menopause Society
1918:), a Merck product for treating
1202:In January 2015, Merck acquired
1051:and other parasitic infections.
925:. At the time of its discovery,
375:
374:
358:
357:
341:
340:
324:
323:
301:
300:
71:Merck's branch office campus in
49:
43:
6839:from the original on 2022-06-15
6399:10.1016/j.maturitas.2013.05.013
6239:Rout, Milanda (April 1, 2009).
5291:from the original on 2022-07-09
4663:
4645:
4627:
4609:
4589:
4571:
4553:
4513:
4495:
4477:
4459:
4422:
4410:"Merck cuts another 8,500 jobs"
4402:
4381:
4351:American City Business Journals
4338:
4317:
4296:
4273:
4252:
4155:
4131:
4110:
4084:
4033:
3991:
3973:
3951:
3833:
3809:
3746:
3732:
3703:
3674:
3656:
3636:
3616:
3596:
3545:
3517:New England Journal of Medicine
3504:
3451:
3420:
3394:
3377:"Drugs@FDA: FDA-Approved Drugs"
3369:
3328:
3282:
3210:
3188:
3140:
3122:
3083:
3069:
3044:
3019:
2992:
2977:
2955:
2935:
2833:
2815:
2808:American City Business Journals
2770:
2752:
2734:
2717:
2700:
2683:
2597:
2579:
2528:
2484:
2437:
2418:
2389:
1818:
1544:Medco Containment Services Inc
1306:
1109:South San Francisco, California
1107:Merck Research Laboratories in
831:, which was established by the
432:Footnotes / references
4824:Bie, Ephraim (June 20, 2018).
4390:"Merck to cut 8,500 more jobs"
3604:"CORPORATIONS: Merck's Merger"
3227:. October 30, 1955. p. 88
2914:Nonmarket Strategic Management
2425:Palmer, Eric (June 17, 2014).
2369:
2351:
2333:
2319:
2298:
2277:
2259:
2228:
2151:
2131:, an animal carcinogen on the
2048:Merck KGaA, Darmstadt, Germany
1252:retinoic acid-inducible gene I
1054:In 1982, the company formed a
763:is an antiviral pill to treat
13:
1:
7610:Institute for OneWorld Health
6312:(1): 25–54, quiz 55–6. 2010.
6084:American Enterprise Institute
6005:10.1016/S0016-5085(89)80061-7
5415:Schmidt, Ann (July 1, 2021).
4222:"Merck, Elsevier, and Fakery"
3571:10.1016/j.vaccine.2020.05.037
3479:10.1016/j.vaccine.2020.05.037
2827:National Institutes of Health
2359:"Fortune 500: Merck & Co"
2198:
2110:In 2021, an investigation by
2071:trade mark rights in the UK.
2016:A fraud investigation by the
1260:In June 2018, Merck acquired
1224:indoleamine-2,3-dioxygenase 1
389:
8246:Dow Jones Industrial Average
7829:West Pharmaceutical Services
6471:10.3109/09513590.2013.813468
6318:10.1097/gme.0b013e3181c617e6
5025:New Jersey Business magazine
4445:10.1016/j.drudis.2014.03.018
4220:Lowe, Derek (May 11, 2009).
4005:Clinical Infectious Diseases
3629:Chemical Institute of Canada
3005:. Harvard University Press.
2785:Food and Drug Administration
2742:"Drug Database: Raltegravir"
2633:10.1371/journal.pone.0030275
2097:
1324:New Jersey Business magazine
1269:Food and Drug Administration
1254:pathway, for $ 554 million.
1098:
933:
171:; 107 years ago
154:; 133 years ago
30:Not to be confused with the
7:
7259:Merck Headquarters Building
6213:Giles, J. (November 2008).
5812:September 16, 2008, at the
3781:Segal, David (2011-01-28).
3664:"Mumps—History of Vaccines"
3026:Colditz, Graham A. (2015).
2840:Zimmer, Carl (2021-06-17).
2105:
1840:Patient assistance programs
1502:Merck & Co Acquisitions
1429:, used in the treatment of
1403:Emergency Use Authorization
1290:, for up to $ 2.2 billion.
1244:Lynparza from AstraZeneca.
589:neuromuscular-blocking drug
502:
180:, as an independent company
10:
8553:
7635:McNeil Consumer Healthcare
6435:10.1016/j.bone.2013.09.023
6347:Hauk, Lisa (August 2013).
6215:"How Merck Made a Killing"
3435:Cambridge University Press
3403:"All Awards & Winners"
3079:. PM Live. April 14, 2014.
2984:Lillard, Benjamin (1908).
2127:Merck & Co. once used
2119:death linked to Propecia.
2038:"Merck" name legal dispute
1982:
1901:Lawsuits and controversies
1601:Imperial Blue Corporation
1377:Munich Security Conference
1240:In 2017, Merck bought the
1228:tryptophan 2,3-dioxygenase
1118:purchased stock in Merck.
1077:, the first member of the
839:purchased a drug store in
805:
796:
791:Royal Society of Chemistry
771:Merck & Co. publishes
29:
8252:
8198:
8141:Smith, Kline & French
7953:
7837:
7692:Northwest Biotherapeutics
7677:Merrimack Pharmaceuticals
7462:
7391:
7362:
7267:
7251:
7065:
7029:
6968:
6827:"ISPOR Asia Pacific 2020"
6354:American Family Physician
5281:Nuclear Threat Initiative
5058:"Merck to Acquire Themis"
2147:Public-private engagement
1887:World Health Organization
1869:Mectizan donation program
1717:Cascade Merger Sub, Inc.
1650:Afferent Pharmaceuticals
1546:(Acq 1993, Spun off 2003)
1284:Von Hippel–Lindau disease
1090:volatile organic compound
1012:), the first drug of the
609:antiretroviral medication
523:, biologic therapies and
450:company headquartered in
430:
399:
383:
366:
349:
332:
315:
296:
250:
225:
215:
204:
187:
145:
135:
93:
83:
64:
42:
5998:(2 Pt 2 Suppl): 647–55.
5808:Retrieved May 20, 2008.
3051:Hawthorne, Fran (2003).
2189:pharmaceutical companies
2141:West Point, Pennsylvania
2123:Environmental violations
1905:
1824:Merck Company Foundation
1775:Astros Merger Sub, Inc.
1628:Optimer Pharmaceuticals
1462:Inc for $ 10.8 billion.
1453:antibody-drug conjugates
1317:Bruton's tyrosine kinase
1209:In July 2015, Merck and
575:used to protect against
557:anti-diabetic medication
379:US$ 37.58 billion (2023)
362:US$ 106.7 billion (2023)
328:US$ 1.889 billion (2023)
57:Chermayeff & Geismar
5834:Retrieved May 20, 2008.
4927:The Dallas Morning News
4485:"Merck acquires Idenix"
4374:The Wall Street Journal
4169:The Wall Street Journal
4046:Harvard Business Review
3354:10.1161/01.hyp.22.3.388
3156:The Wall Street Journal
2882:"Key Facts About Merck"
2244:The Wall Street Journal
2137:Riverside, Pennsylvania
1877:to donate its new drug
1788:Prometheus Biosciences
1746:Argon Merger Sub, Inc.
1683:PrognostiX Poultry Ltd
1604:Idenix Pharmaceuticals
1532:Sharp & Dohme, Inc
1401:and that it would seek
1363:antibody-drug conjugate
871:After the U.S. entered
820:, the beginning of the
802:Roots and early history
460:Merck Sharp & Dohme
140:Pharmaceutical industry
8497:Kenilworth, New Jersey
8066:Leiner Health Products
7510:Amneal Pharmaceuticals
7378:Heinrich Emanuel Merck
7042:Cubist Pharmaceuticals
6864:. 2020. Archived from
6521:Cite journal requires
6265:Retrieved May 19, 2008
5156:on September 14, 2020.
3381:www.accessdata.fda.gov
2999:Wilkins, Mira (1989).
2397:"The Global 2000 2023"
1616:Cubist Pharmaceuticals
1577:Organon International
1538:Charles E. Frosst Ltd
1526:H. K. Mulford Company
1487:small cell lung cancer
1460:Prometheus Biosciences
1431:pulmonary hypertension
1204:Cubist Pharmaceuticals
1184:new molecular entities
1111:
824:
816:The Angel Pharmacy in
690:ankylosing spondylitis
632:immunosuppressive drug
512:
345:US$ 365 million (2023)
268:over-the-counter drugs
73:Upper Gwynedd Township
8342:Johnson & Johnson
7620:Johnson & Johnson
7413:Merck & Co. (MSD)
7406:H. J. Merck & Co.
7372:Friedrich Jacob Merck
7199:Ezetimibe/simvastatin
7093:Ezetimibe/simvastatin
7047:H. K. Mulford Company
6962:Merck & Co., Inc.
6709:. Reuters. 2007-02-14
6086:. September 30, 2005.
5898:"MerckforMothers.com"
5524:. September 30, 2021.
5216:on November 23, 2020.
5096:on September 5, 2020.
4852:. September 17, 2019.
4774:McLean (2017-10-05).
4102:. November 19, 1993.
3296:See Preface material.
3248:J Hist Med Allied Sci
2064:High Court of Justice
1855:Hilleman Laboratories
1849:Hilleman Laboratories
1834:Boy Scouts of America
1800:Harpoon Therapeutics
1794:Caraway Therapeutics
1728:Peloton Therapeutics
1563:Schering Corporation
1491:neuroendocrine tumors
1470:and biliary cancers.
1163:Johnson & Johnson
1106:
1068:Johnson & Johnson
951:H. K. Mulford Company
904:H. K. Mulford Company
851:and later introduced
837:Friedrich Jacob Merck
815:
708:human papilloma virus
515:The company develops
510:
488:and 87th on the 2022
441:Merck & Co., Inc.
163:, as a subsidiary of
38:Merck & Co., Inc.
8372:Procter & Gamble
7914:Jazz Pharmaceuticals
7904:Horizon Therapeutics
7774:Sarepta Therapeutics
7749:Proteon Therapeutics
7744:Procter & Gamble
7657:Melinta Therapeutics
7550:Bristol Myers Squibb
6225:on October 27, 2008.
6032:www.medpagetoday.com
5942:. February 24, 1981.
5936:"Ivermectin History"
5744:Merck Responsibility
5538:. 22 September 2022.
5260:. February 25, 2021.
4990:. December 17, 2019.
4969:. November 13, 2019.
4763:. September 6, 2017.
4745:. September 6, 2017.
4527:. December 18, 2014.
4509:. December 18, 2014.
4432:Drug Discovery Today
4080:. September 5, 1996.
3987:. December 31, 2014.
3530:10.1056/NEJMc1707600
3401:Hofschneider, Mark.
3260:10.1093/jhmas/jrh091
2919:Taylor & Francis
2766:. September 5, 2014.
2593:. November 17, 2014.
2224:. February 26, 2024.
2012:Medicaid overbilling
1656:Merck Animal Health
1475:Harpoon Therapeutics
1288:renal cell carcinoma
1161:. A settlement with
1045:lymphatic filariasis
682:rheumatoid arthritis
545:cancer immunotherapy
8121:Repros Therapeutics
8036:Forest Laboratories
8021:Cutter Laboratories
7739:Prasco Laboratories
7480:Acorda Therapeutics
7470:Abbott Laboratories
6969:Corporate directors
6671:. January 15, 2016.
6609:. February 7, 2008.
6591:. February 7, 2008.
6570:The Washington Post
6549:. December 9, 2013.
6459:Gynecol. Endocrinol
6202:. November 9, 2007.
6181:. November 9, 2007.
6080:"The Vioxx Fallout"
5940:Stanford University
5336:. 25 February 2021.
5008:. January 16, 2020.
4972:Coi Pharmaceuticals
4659:. January 11, 2016.
4567:. January 21, 2015.
3926:"Satoshi Omura PhD"
3886:2011PJAB...87...13C
3196:"Our History: 1925"
3184:. January 15, 2016.
3118:. January 15, 2016.
2973:. October 29, 2017.
2948:The Palm Beach Post
2895:. November 3, 2005.
2624:2012PLoSO...730275A
2494:Diabetes Obes Metab
2181:government agencies
2179:that also includes
1734:Tilos Therapeutics
1720:Immune Design Corp
1497:Acquisition history
1446:Merck Animal Health
1365:designed to target
1021:William C. Campbell
988:Hepatitis B vaccine
978:in 1967, the first
628:monoclonal antibody
454:, and is named for
385:Number of employees
288:Veterinary medicine
39:
8244:Components of the
8081:Miles Laboratories
8071:Martek Biosciences
7894:Endo International
7814:Ventria Bioscience
7580:Danco Laboratories
7224:Rocuronium bromide
7148:rVSV-ZEBOV vaccine
6283:The New York Times
6219:Healthy Scepticism
6178:The New York Times
6155:The New York Times
6057:The New York Times
5975:. 29 January 2018.
5830:2012-03-20 at the
5608:. 19 December 2023
5354:. 25 February 2021
5234:. 23 November 2020
4641:. January 6, 2016.
4623:. January 6, 2016.
4418:. October 1, 2013.
4289:The New York Times
4206:The New York Times
4151:. August 20, 2003.
3894:10.2183/pjab.87.13
3788:The New York Times
3225:The New York Times
2888:The New York Times
2847:The New York Times
2164:Political lobbying
2129:methylene chloride
1757:Themis Bioscience
1621:Trius Therapeutics
1612:Maven Corporation
1514:Merck of Darmstadt
1413:corporate spin-off
1112:
994:, for chickenpox.
919:Rutgers University
825:
541:humanized antibody
513:
497:Forbes Global 2000
452:Rahway, New Jersey
209:Rahway, New Jersey
37:
8477:Vaccine producers
8410:
8409:
8211:
8210:
8194:
8193:
8026:DNAPrint Genomics
7515:Avax Technologies
7422:
7421:
7322:
7321:
7283:The Merck Manuals
7247:
7246:
6766:. 4 February 2021
6689:. April 29, 2020.
6587:(Press release).
5629:. 8 January 2024.
5520:(Press release).
5502:(Press release).
5312:(Press release).
5256:(Press release).
5132:. August 5, 2020.
5128:(Press release).
5110:(Press release).
5042:(Press release).
5028:. March 11, 2020.
5004:(Press release).
4986:(Press release).
4965:(Press release).
4905:(Press release).
4887:(Press release).
4848:(Press release).
4759:(Press release).
4727:. March 22, 2017.
4723:(Press release).
4709:. March 17, 2022.
4563:(Press release).
4523:(Press release).
4473:. August 5, 2014.
4469:(Press release).
4354:. April 15, 2011.
4244:(Press release).
4099:The Baltimore Sun
3612:. March 16, 1953.
3564:(30): 4773–4779.
3523:(15): 1491–1492.
3472:(30): 4773–4779.
3444:978-0-521-62620-0
3407:Lasker Foundation
3335:Beyer KH (1993).
3037:978-1-4833-4574-1
2928:978-1-317-42173-3
2671:(Press release).
2555:10.1136/bmj.g2366
2273:. March 24, 2021.
1928:anti-inflammatory
1861:Merck for Mothers
1435:luspatercept-aamt
1417:Organon & Co.
1139:Raymond Gilmartin
1114:In May 2002, The
1058:, KBI Inc., with
992:varicella vaccine
774:The Merck Manuals
636:rotavirus vaccine
573:varicella vaccine
529:blockbuster drugs
438:
437:
413:(US & Canada)
152:January 1891
18:Merck and Company
16:(Redirected from
8544:
8439:
8438:
8437:
8427:
8426:
8425:
8418:
8267:American Express
8238:
8231:
8224:
8215:
8214:
7842:
7841:
7789:Tec Laboratories
7662:Melior Discovery
7647:Kinetic Concepts
7590:Galena Biopharma
7449:
7442:
7435:
7426:
7425:
7349:
7342:
7335:
7326:
7325:
7174:
7173:
7037:Acceleron Pharma
6996:Rochelle Lazarus
6986:William Harrison
6955:
6948:
6941:
6932:
6931:
6895:
6894:
6892:Official website
6877:
6876:
6874:
6873:
6854:
6848:
6847:
6845:
6844:
6823:
6817:
6816:
6805:
6799:
6798:
6796:
6795:
6781:
6775:
6774:
6772:
6771:
6756:
6750:
6749:
6747:
6746:
6729:
6718:
6717:
6715:
6714:
6697:
6691:
6690:
6679:
6673:
6672:
6661:
6655:
6654:
6646:
6638:
6632:
6631:
6617:
6611:
6610:
6599:
6593:
6592:
6581:
6575:
6574:
6560:
6551:
6550:
6537:
6531:
6530:
6524:
6519:
6517:
6509:
6497:
6491:
6490:
6453:
6447:
6446:
6418:
6412:
6411:
6401:
6377:
6371:
6370:
6344:
6338:
6337:
6298:
6292:
6291:
6288:Associated Press
6279:
6272:
6266:
6257:
6251:
6250:
6236:
6230:
6226:
6221:. Archived from
6210:
6204:
6203:
6197:
6189:
6183:
6182:
6169:
6160:
6159:
6151:
6146:(May 30, 2008).
6140:
6131:
6130:
6094:
6088:
6087:
6076:
6070:
6069:
6053:
6042:
6036:
6035:
6024:
6018:
6017:
6007:
5992:Gastroenterology
5983:
5977:
5976:
5965:
5956:
5950:
5944:
5943:
5932:
5926:
5925:
5908:
5902:
5901:
5894:
5888:
5887:
5871:
5865:
5864:
5862:
5860:
5851:. Archived from
5841:
5835:
5822:
5816:
5803:
5797:
5796:
5782:
5776:
5775:
5773:
5765:
5759:
5758:
5756:
5755:
5746:. Archived from
5736:
5730:
5729:
5723:
5715:
5709:
5708:
5701:
5695:
5694:
5688:
5680:
5674:
5673:
5666:
5660:
5659:
5657:
5656:
5637:
5631:
5630:
5623:
5617:
5616:
5614:
5613:
5598:
5592:
5591:
5577:
5571:
5570:
5568:
5566:
5546:
5540:
5539:
5532:
5526:
5525:
5514:
5508:
5507:
5496:
5490:
5489:
5475:
5469:
5468:
5454:
5448:
5447:
5433:
5427:
5426:
5412:
5406:
5405:
5391:
5385:
5384:
5370:
5364:
5363:
5361:
5359:
5344:
5338:
5337:
5324:
5318:
5317:
5316:. April 1, 2021.
5306:
5300:
5299:
5297:
5296:
5290:
5277:
5268:
5262:
5261:
5250:
5244:
5243:
5241:
5239:
5224:
5218:
5217:
5212:. Archived from
5199:
5193:
5192:
5185:
5179:
5178:
5164:
5158:
5157:
5140:
5134:
5133:
5122:
5116:
5115:
5114:. June 17, 2020.
5104:
5098:
5097:
5092:. Archived from
5079:
5073:
5072:
5070:
5068:
5054:
5048:
5047:
5046:. June 19, 2020.
5036:
5030:
5029:
5016:
5010:
5009:
4998:
4992:
4991:
4980:
4974:
4970:
4959:
4953:
4952:
4938:
4932:
4931:
4917:
4911:
4910:
4909:. April 1, 2019.
4899:
4893:
4892:
4891:. April 2, 2019.
4881:
4875:
4874:
4860:
4854:
4853:
4842:
4836:
4835:
4821:
4815:
4814:
4812:
4811:
4796:
4790:
4789:
4787:
4786:
4771:
4765:
4764:
4753:
4747:
4746:
4735:
4729:
4728:
4717:
4711:
4710:
4703:
4697:
4696:
4695:. June 10, 2016.
4685:
4679:
4678:
4667:
4661:
4660:
4649:
4643:
4642:
4631:
4625:
4624:
4613:
4607:
4606:
4605:. July 28, 2015.
4593:
4587:
4586:
4575:
4569:
4568:
4557:
4551:
4550:
4538:
4529:
4528:
4517:
4511:
4510:
4499:
4493:
4492:
4481:
4475:
4474:
4463:
4457:
4456:
4426:
4420:
4419:
4406:
4400:
4399:
4385:
4379:
4378:
4370:
4362:
4356:
4355:
4342:
4336:
4335:
4321:
4315:
4314:
4300:
4294:
4293:
4285:
4277:
4271:
4270:
4256:
4250:
4249:
4238:
4232:
4231:
4217:
4211:
4210:
4202:
4194:
4188:
4187:
4185:
4184:
4159:
4153:
4152:
4149:Associated Press
4135:
4129:
4128:
4124:Associated Press
4114:
4108:
4107:
4095:
4088:
4082:
4081:
4070:
4064:
4063:
4061:
4060:
4037:
4031:
4030:
4020:
3995:
3989:
3988:
3977:
3971:
3970:
3968:
3966:
3955:
3949:
3943:
3937:
3936:
3934:
3932:
3922:
3916:
3915:
3905:
3865:
3856:
3855:
3853:
3851:
3837:
3831:
3830:
3828:
3827:
3813:
3807:
3806:
3804:
3803:
3778:
3769:
3768:
3766:
3765:
3750:
3744:
3743:
3736:
3730:
3729:
3727:
3726:
3717:. Archived from
3707:
3701:
3700:
3698:
3697:
3688:. Archived from
3678:
3672:
3671:
3660:
3654:
3653:
3640:
3634:
3633:
3632:. November 2014.
3620:
3614:
3613:
3600:
3594:
3593:
3583:
3573:
3549:
3543:
3542:
3532:
3508:
3502:
3501:
3491:
3481:
3455:
3449:
3448:
3424:
3418:
3417:
3415:
3413:
3398:
3392:
3391:
3389:
3387:
3373:
3367:
3366:
3356:
3332:
3326:
3325:
3321:978-184129-012-6
3313:
3303:
3297:
3286:
3280:
3279:
3243:
3237:
3236:
3234:
3232:
3222:
3214:
3208:
3207:
3205:
3203:
3192:
3186:
3185:
3172:
3161:
3160:
3152:
3144:
3138:
3137:
3126:
3120:
3119:
3108:
3099:
3098:
3087:
3081:
3080:
3073:
3067:
3066:
3048:
3042:
3041:
3023:
3017:
3016:
2996:
2990:
2989:
2981:
2975:
2974:
2971:Associated Press
2959:
2953:
2952:
2951:. June 28, 2018.
2939:
2933:
2932:
2908:
2897:
2896:
2893:Associated Press
2884:
2877:
2866:
2865:
2863:
2862:
2837:
2831:
2830:
2819:
2813:
2812:
2798:
2789:
2788:
2782:
2774:
2768:
2767:
2756:
2750:
2749:
2738:
2732:
2731:
2729:
2721:
2715:
2714:
2712:
2704:
2698:
2697:
2696:. July 24, 2017.
2687:
2681:
2680:
2665:
2656:
2655:
2645:
2635:
2601:
2595:
2594:
2583:
2577:
2576:
2566:
2532:
2526:
2525:
2488:
2482:
2481:
2441:
2435:
2434:
2422:
2416:
2415:
2413:
2412:
2403:. Archived from
2393:
2387:
2386:
2373:
2367:
2366:
2355:
2349:
2348:
2337:
2331:
2330:
2323:
2317:
2316:
2314:
2312:
2302:
2296:
2295:
2281:
2275:
2274:
2263:
2257:
2256:
2240:
2232:
2226:
2225:
2214:
2177:advocacy network
2022:False Claims Act
1970:academic freedom
1924:cyclooxygenase-2
1809:
1803:
1797:
1791:
1783:
1779:Acceleron Pharma
1772:
1766:
1760:
1752:
1743:
1737:
1731:
1723:
1714:
1708:
1700:
1692:
1686:
1680:
1674:
1668:
1662:
1653:
1647:
1641:
1631:
1625:
1607:
1583:
1572:
1566:
1560:
1552:Schering‑Plough
1547:
1541:
1535:
1529:
1517:
1423:Acceleron Pharma
1356:Seattle Genetics
1019:Merck scientist
972:Maurice Hilleman
953:in 1929, adding
915:Selman Waksman's
694:plaque psoriasis
422:
419:
412:
409:
394:
391:
378:
377:
371:
361:
360:
354:
344:
343:
327:
326:
318:Operating income
310:
304:
303:
246:
231:Robert M. Davis
194:Theodore Weicker
179:
177:
172:
162:
160:
155:
69:
53:
47:
40:
36:
21:
8552:
8551:
8547:
8546:
8545:
8543:
8542:
8541:
8537:Schering-Plough
8457:Merck & Co.
8447:
8446:
8445:
8435:
8433:
8423:
8421:
8413:
8411:
8406:
8248:
8242:
8212:
8207:
8190:
8136:Schering-Plough
8046:ImClone Systems
7949:
7833:
7682:Myriad Genetics
7672:Merck & Co.
7630:Janssen Biotech
7600:Gilead Sciences
7458:
7453:
7423:
7418:
7387:
7383:George W. Merck
7358:
7353:
7323:
7318:
7263:
7243:
7184:Coppertone sign
7177:Schering-Plough
7172:
7061:
7052:Schering-Plough
7025:
6964:
6959:
6927:
6890:
6889:
6886:
6881:
6880:
6871:
6869:
6856:
6855:
6851:
6842:
6840:
6825:
6824:
6820:
6807:
6806:
6802:
6793:
6791:
6783:
6782:
6778:
6769:
6767:
6758:
6757:
6753:
6744:
6742:
6731:
6730:
6721:
6712:
6710:
6699:
6698:
6694:
6681:
6680:
6676:
6663:
6662:
6658:
6639:
6635:
6618:
6614:
6601:
6600:
6596:
6583:
6582:
6578:
6561:
6554:
6539:
6538:
6534:
6522:
6520:
6511:
6510:
6498:
6494:
6465:(12): 1005–14.
6454:
6450:
6419:
6415:
6378:
6374:
6345:
6341:
6300:
6299:
6295:
6290:. May 20, 2008.
6274:
6273:
6269:
6258:
6254:
6237:
6233:
6211:
6207:
6195:
6191:
6190:
6186:
6171:
6170:
6163:
6141:
6134:
6095:
6091:
6078:
6077:
6073:
6043:
6039:
6026:
6025:
6021:
5984:
5980:
5967:
5966:
5959:
5951:
5947:
5934:
5933:
5929:
5910:
5909:
5905:
5900:. 4 March 2021.
5896:
5895:
5891:
5872:
5868:
5858:
5856:
5855:on 27 July 2011
5843:
5842:
5838:
5832:Wayback Machine
5823:
5819:
5814:Wayback Machine
5804:
5800:
5783:
5779:
5774:. May 22, 2007.
5771:
5767:
5766:
5762:
5753:
5751:
5738:
5737:
5733:
5721:
5717:
5716:
5712:
5703:
5702:
5698:
5686:
5682:
5681:
5677:
5672:. 8 April 2024.
5668:
5667:
5663:
5654:
5652:
5639:
5638:
5634:
5625:
5624:
5620:
5611:
5609:
5600:
5599:
5595:
5578:
5574:
5564:
5562:
5547:
5543:
5534:
5533:
5529:
5516:
5515:
5511:
5506:. June 3, 2021.
5498:
5497:
5493:
5476:
5472:
5455:
5451:
5434:
5430:
5413:
5409:
5392:
5388:
5371:
5367:
5357:
5355:
5346:
5345:
5341:
5326:
5325:
5321:
5308:
5307:
5303:
5294:
5292:
5288:
5275:
5269:
5265:
5252:
5251:
5247:
5237:
5235:
5226:
5225:
5221:
5200:
5196:
5187:
5186:
5182:
5165:
5161:
5142:
5141:
5137:
5124:
5123:
5119:
5106:
5105:
5101:
5080:
5076:
5066:
5064:
5056:
5055:
5051:
5038:
5037:
5033:
5018:
5017:
5013:
5000:
4999:
4995:
4982:
4981:
4977:
4961:
4960:
4956:
4939:
4935:
4918:
4914:
4901:
4900:
4896:
4883:
4882:
4878:
4861:
4857:
4844:
4843:
4839:
4822:
4818:
4809:
4807:
4797:
4793:
4784:
4782:
4772:
4768:
4755:
4754:
4750:
4737:
4736:
4732:
4719:
4718:
4714:
4705:
4704:
4700:
4687:
4686:
4682:
4669:
4668:
4664:
4651:
4650:
4646:
4633:
4632:
4628:
4615:
4614:
4610:
4595:
4594:
4590:
4577:
4576:
4572:
4559:
4558:
4554:
4539:
4532:
4519:
4518:
4514:
4501:
4500:
4496:
4491:. June 9, 2014.
4483:
4482:
4478:
4465:
4464:
4460:
4427:
4423:
4408:
4407:
4403:
4386:
4382:
4363:
4359:
4344:
4343:
4339:
4322:
4318:
4301:
4297:
4278:
4274:
4257:
4253:
4240:
4239:
4235:
4218:
4214:
4195:
4191:
4182:
4180:
4160:
4156:
4137:
4136:
4132:
4115:
4111:
4090:
4089:
4085:
4072:
4071:
4067:
4058:
4056:
4038:
4034:
3996:
3992:
3979:
3978:
3974:
3964:
3962:
3957:
3956:
3952:
3944:
3940:
3930:
3928:
3924:
3923:
3919:
3866:
3859:
3849:
3847:
3839:
3838:
3834:
3825:
3823:
3815:
3814:
3810:
3801:
3799:
3779:
3772:
3763:
3761:
3752:
3751:
3747:
3738:
3737:
3733:
3724:
3722:
3709:
3708:
3704:
3695:
3693:
3680:
3679:
3675:
3662:
3661:
3657:
3652:. July 8, 2010.
3642:
3641:
3637:
3622:
3621:
3617:
3602:
3601:
3597:
3550:
3546:
3509:
3505:
3456:
3452:
3445:
3425:
3421:
3411:
3409:
3399:
3395:
3385:
3383:
3375:
3374:
3370:
3333:
3329:
3322:
3304:
3300:
3287:
3283:
3244:
3240:
3230:
3228:
3220:
3216:
3215:
3211:
3201:
3199:
3194:
3193:
3189:
3174:
3173:
3164:
3147:Dauer, Ulrike.
3145:
3141:
3127:
3123:
3110:
3109:
3102:
3089:
3088:
3084:
3075:
3074:
3070:
3063:
3049:
3045:
3038:
3024:
3020:
3013:
2997:
2993:
2982:
2978:
2961:
2960:
2956:
2941:
2940:
2936:
2929:
2909:
2900:
2879:
2878:
2869:
2860:
2858:
2838:
2834:
2821:
2820:
2816:
2799:
2792:
2780:
2776:
2775:
2771:
2758:
2757:
2753:
2740:
2739:
2735:
2727:
2723:
2722:
2718:
2710:
2706:
2705:
2701:
2689:
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2299:
2282:
2278:
2265:
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2260:
2233:
2229:
2216:
2215:
2206:
2201:
2193:lobbying groups
2174:health research
2166:
2154:
2149:
2125:
2108:
2100:
2040:
2014:
1985:
1951:COX-2 inhibitor
1908:
1903:
1871:
1863:
1851:
1842:
1826:
1821:
1816:
1815:
1814:
1807:
1801:
1795:
1789:
1781:
1770:
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1750:
1741:
1735:
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1721:
1712:
1711:Antelliq Group
1706:
1698:
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1684:
1678:
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1660:
1651:
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1639:
1629:
1623:
1605:
1581:
1570:
1564:
1558:
1556:Schering-Plough
1545:
1539:
1533:
1527:
1523:Merck & Co
1520:Merck & Co
1511:
1503:
1499:
1309:
1173:Kenneth Frazier
1154:Schering-Plough
1101:
1041:river blindness
980:rubella vaccine
936:
896:George W. Merck
889:Lehman Brothers
869:
867:Nationalization
810:
804:
799:
786:The Merck Index
755:river blindness
698:Janssen Biotech
686:Crohn's disease
561:type 2 diabetes
505:
443:is an American
434:
426:
423:(international)
416:
406:
392:
386:
367:
350:
337:
320:
305:
292:
258:Pharmaceuticals
232:
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218:
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183:
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170:
158:
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131:
98:
79:
60:
48:
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28:
23:
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15:
12:
11:
5:
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8399:
8394:
8389:
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8379:
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8369:
8364:
8359:
8354:
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8347:JPMorgan Chase
8344:
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8334:
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8324:
8319:
8314:
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8299:
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7988:
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7978:
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7968:
7966:Allergan, Inc.
7963:
7957:
7955:
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7950:
7948:
7947:
7946:(Canada, 2010)
7941:
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7697:Norwich Pharma
7694:
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7239:Urofollitropin
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7027:
7026:
7024:
7023:
7018:
7013:
7008:
7003:
6998:
6993:
6991:William Kelley
6988:
6983:
6981:Johnnetta Cole
6978:
6972:
6970:
6966:
6965:
6958:
6957:
6950:
6943:
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6929:
6928:
6926:
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6920:
6915:
6910:
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6899:
6896:
6885:
6884:External links
6882:
6879:
6878:
6849:
6818:
6800:
6776:
6751:
6719:
6692:
6674:
6656:
6650:Bloomberg News
6633:
6612:
6594:
6576:
6552:
6532:
6523:|journal=
6492:
6448:
6413:
6372:
6339:
6293:
6267:
6252:
6246:The Australian
6231:
6205:
6184:
6161:
6144:Berenson, Alex
6132:
6089:
6071:
6046:Berenson, Alex
6037:
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4912:
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4876:
4855:
4837:
4831:S&P Global
4816:
4791:
4766:
4748:
4743:genengnews.com
4730:
4712:
4698:
4693:genengnews.com
4680:
4662:
4657:genengnews.com
4644:
4639:genengnews.com
4626:
4621:genengnews.com
4608:
4588:
4583:genengnews.com
4570:
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4530:
4512:
4507:genengnews.com
4494:
4489:genengnews.com
4476:
4458:
4421:
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4380:
4357:
4337:
4316:
4295:
4272:
4251:
4248:. May 7, 2009.
4233:
4212:
4189:
4154:
4130:
4109:
4083:
4065:
4032:
4018:10.1086/649554
4011:(2): 133–164.
3990:
3972:
3950:
3948:NobelPrize.org
3938:
3917:
3857:
3832:
3808:
3770:
3756:Archived from
3745:
3731:
3702:
3673:
3655:
3635:
3624:"Then and Now"
3615:
3595:
3544:
3503:
3450:
3443:
3419:
3393:
3368:
3327:
3320:
3298:
3281:
3238:
3209:
3187:
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3139:
3121:
3116:genengnews.com
3100:
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3011:
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2976:
2954:
2934:
2927:
2898:
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2832:
2814:
2790:
2769:
2764:genengnews.com
2751:
2733:
2716:
2699:
2694:genengnews.com
2682:
2679:on 2012-07-08.
2657:
2596:
2578:
2527:
2483:
2436:
2417:
2388:
2368:
2350:
2345:Bru Times News
2332:
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2203:
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2107:
2104:
2099:
2096:
2077:cybersquatting
2068:United Kingdom
2039:
2036:
2013:
2010:
1993:bisphosphonate
1984:
1981:
1946:clinical trial
1930:drugs such as
1907:
1904:
1902:
1899:
1883:onchocerciasis
1870:
1867:
1862:
1859:
1850:
1847:
1841:
1838:
1825:
1822:
1820:
1817:
1813:
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1804:
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1773:
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1755:
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1744:
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1726:
1725:
1724:
1715:
1709:
1701:
1695:
1694:
1693:
1687:
1681:
1675:
1671:Quantified Ag
1669:
1663:
1654:
1648:
1642:
1636:
1635:
1634:
1633:
1632:
1626:
1610:
1609:
1608:
1599:
1598:
1597:
1596:
1595:
1592:
1589:
1586:
1585:
1584:
1580:Alydia Health
1575:
1574:
1573:
1571:(Founded 1908)
1567:
1565:(Founded 1851)
1550:
1549:
1548:
1542:
1536:
1530:
1509:Merck & Co
1505:
1504:
1501:
1500:
1498:
1495:
1405:for the drug.
1308:
1305:
1242:PARP inhibitor
1100:
1097:
1083:P. Roy Vagelos
1037:Onchocerciasis
990:and the first
962:Charles Frosst
944:chlorothiazide
938:In the 1950s,
935:
932:
917:laboratory at
868:
865:
806:Main article:
803:
800:
798:
795:
769:
768:
758:
748:
742:
731:
721:
711:
701:
671:
665:
648:ovarian cancer
611:used to treat
559:used to treat
504:
501:
448:pharmaceutical
436:
435:
428:
427:
425:
424:
414:
403:
401:
397:
396:
387:
384:
381:
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372:
364:
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355:
347:
346:
338:
333:
330:
329:
321:
316:
313:
312:
298:
294:
293:
291:
290:
285:
283:contact lenses
280:
275:
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265:
260:
254:
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248:
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229:
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219:
216:
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167:
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54:
26:
9:
6:
4:
3:
2:
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8508:
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8500:
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8495:
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8488:
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8483:
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8442:
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8403:
8400:
8398:
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8380:
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8370:
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8360:
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8353:
8350:
8348:
8345:
8343:
8340:
8338:
8335:
8333:
8330:
8328:
8325:
8323:
8320:
8318:
8317:Goldman Sachs
8315:
8313:
8310:
8308:
8305:
8303:
8300:
8298:
8295:
8293:
8290:
8288:
8285:
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8280:
8278:
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8260:
8258:
8255:
8254:
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8239:
8234:
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8227:
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8219:
8216:
8204:
8201:
8200:
8197:
8187:
8184:
8182:
8179:
8177:
8174:
8172:
8169:
8167:
8164:
8162:
8159:
8157:
8154:
8152:
8149:
8147:
8146:Sterling Drug
8144:
8142:
8139:
8137:
8134:
8132:
8129:
8127:
8124:
8122:
8119:
8117:
8114:
8112:
8109:
8107:
8104:
8102:
8099:
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8092:
8089:
8087:
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8079:
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8064:
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8059:
8057:
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8052:
8049:
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8029:
8027:
8024:
8022:
8019:
8017:
8014:
8012:
8009:
8007:
8004:
8002:
7999:
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7994:
7992:
7989:
7987:
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7982:
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7977:
7974:
7972:
7969:
7967:
7964:
7962:
7959:
7958:
7956:
7952:
7945:
7944:Bausch Health
7942:
7939:
7935:
7932:
7929:
7925:
7922:
7919:
7915:
7912:
7909:
7905:
7902:
7899:
7895:
7892:
7889:
7885:
7882:
7879:
7875:
7872:
7869:
7865:
7862:
7859:
7855:
7852:
7851:
7849:
7847:
7846:Tax inversion
7843:
7840:
7836:
7830:
7827:
7825:
7822:
7820:
7817:
7815:
7812:
7810:
7807:
7805:
7802:
7800:
7797:
7795:
7792:
7790:
7787:
7785:
7782:
7780:
7777:
7775:
7772:
7770:
7767:
7765:
7762:
7760:
7757:
7755:
7754:Purdue Pharma
7752:
7750:
7747:
7745:
7742:
7740:
7737:
7735:
7732:
7728:
7725:
7723:
7720:
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7708:
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7703:
7700:
7698:
7695:
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7678:
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7641:
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7616:
7613:
7611:
7608:
7606:
7603:
7601:
7598:
7596:
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7588:
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7531:
7528:
7526:
7523:
7521:
7518:
7516:
7513:
7511:
7508:
7506:
7503:
7501:
7498:
7496:
7493:
7491:
7488:
7486:
7483:
7481:
7478:
7476:
7473:
7471:
7468:
7467:
7465:
7461:
7457:
7450:
7445:
7443:
7438:
7436:
7431:
7430:
7427:
7414:
7410:
7407:
7403:
7400:
7397:
7396:
7394:
7390:
7384:
7381:
7379:
7375:
7373:
7370:
7369:
7367:
7365:
7361:
7357:
7350:
7345:
7343:
7338:
7336:
7331:
7330:
7327:
7313:
7312:
7308:
7306:
7305:
7301:
7299:
7298:
7294:
7292:
7291:
7287:
7286:
7285:
7284:
7280:
7278:
7277:
7273:
7272:
7270:
7266:
7260:
7257:
7256:
7254:
7250:
7240:
7237:
7235:
7232:
7230:
7227:
7225:
7222:
7220:
7217:
7215:
7212:
7210:
7207:
7205:
7202:
7200:
7197:
7195:
7192:
7190:
7189:Desloratadine
7187:
7185:
7182:
7181:
7179:
7175:
7169:
7166:
7164:
7161:
7159:
7156:
7154:
7151:
7149:
7146:
7144:
7141:
7139:
7136:
7134:
7131:
7129:
7126:
7124:
7121:
7119:
7116:
7114:
7111:
7109:
7106:
7104:
7103:Fosaprepitant
7101:
7099:
7096:
7094:
7091:
7089:
7086:
7084:
7081:
7079:
7076:
7074:
7071:
7070:
7068:
7064:
7058:
7055:
7053:
7050:
7048:
7045:
7043:
7040:
7038:
7035:
7034:
7032:
7028:
7022:
7021:Peter Wendell
7019:
7017:
7016:Wendell Weeks
7014:
7012:
7009:
7007:
7004:
7002:
6999:
6997:
6994:
6992:
6989:
6987:
6984:
6982:
6979:
6977:
6976:Richard Clark
6974:
6973:
6971:
6967:
6963:
6956:
6951:
6949:
6944:
6942:
6937:
6936:
6933:
6924:
6921:
6919:
6916:
6914:
6911:
6909:
6906:
6904:
6901:
6900:
6897:
6893:
6888:
6887:
6868:on 2022-05-08
6867:
6863:
6862:AcademyHealth
6859:
6853:
6838:
6834:
6833:
6828:
6822:
6815:. 9 May 2013.
6814:
6810:
6804:
6790:
6786:
6780:
6765:
6761:
6755:
6740:
6739:
6734:
6728:
6726:
6724:
6708:
6707:
6702:
6696:
6688:
6684:
6678:
6670:
6669:Fierce Pharma
6666:
6660:
6652:
6651:
6645:
6637:
6629:
6628:
6623:
6616:
6608:
6607:FierceBiotech
6604:
6598:
6590:
6586:
6580:
6572:
6571:
6566:
6559:
6557:
6548:
6547:
6542:
6536:
6528:
6515:
6507:
6503:
6496:
6488:
6484:
6480:
6476:
6472:
6468:
6464:
6460:
6452:
6444:
6440:
6436:
6432:
6428:
6424:
6417:
6409:
6405:
6400:
6395:
6391:
6387:
6383:
6376:
6368:
6364:
6361:(4): 269–75.
6360:
6356:
6355:
6350:
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6335:
6331:
6327:
6323:
6319:
6315:
6311:
6307:
6303:
6297:
6289:
6285:
6284:
6278:
6271:
6264:
6261:
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6248:
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6235:
6229:
6224:
6220:
6216:
6209:
6201:
6194:
6188:
6180:
6179:
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6157:
6156:
6150:
6145:
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6137:
6128:
6124:
6120:
6116:
6112:
6108:
6105:(4): 335–43.
6104:
6100:
6093:
6085:
6081:
6075:
6067:
6063:
6059:
6058:
6052:
6047:
6041:
6034:. 2018-05-02.
6033:
6029:
6023:
6015:
6011:
6006:
6001:
5997:
5993:
5989:
5982:
5974:
5970:
5964:
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5941:
5937:
5931:
5923:
5919:
5918:
5913:
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5893:
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5881:
5880:Fierce Pharma
5877:
5870:
5854:
5850:
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5840:
5833:
5829:
5826:
5821:
5815:
5811:
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5794:
5793:
5788:
5781:
5770:
5764:
5750:on 2015-09-04
5749:
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5741:
5735:
5727:
5720:
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5706:
5700:
5692:
5685:
5679:
5671:
5665:
5651:on 2024-02-28
5650:
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5636:
5628:
5622:
5607:
5603:
5597:
5589:
5588:
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5556:
5555:BiopharmaDive
5552:
5545:
5537:
5531:
5523:
5522:Business Wire
5519:
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5505:
5504:Business Wire
5501:
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5314:Business Wire
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5258:Business Wire
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5130:Business Wire
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5112:Business Wire
5109:
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5044:Business Wire
5041:
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5007:
5006:Business Wire
5003:
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4988:Business Wire
4985:
4979:
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4968:
4967:Business Wire
4964:
4958:
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4904:
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4889:Business Wire
4886:
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4851:
4850:Business Wire
4847:
4841:
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4762:
4761:Business Wire
4758:
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4726:
4725:Business Wire
4722:
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4684:
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4640:
4636:
4630:
4622:
4618:
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4603:
4602:FierceBiotech
4598:
4592:
4584:
4580:
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4566:
4565:Business Wire
4562:
4556:
4548:
4547:Fierce Pharma
4544:
4537:
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4526:
4525:Business Wire
4522:
4516:
4508:
4504:
4498:
4490:
4486:
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4472:
4471:Business Wire
4468:
4462:
4454:
4450:
4446:
4442:
4439:(8): 1033–9.
4438:
4434:
4433:
4425:
4417:
4416:
4411:
4405:
4397:
4396:
4391:
4384:
4376:
4375:
4369:
4361:
4353:
4352:
4347:
4341:
4333:
4332:
4327:
4320:
4312:
4311:
4306:
4299:
4291:
4290:
4284:
4276:
4268:
4267:
4262:
4255:
4247:
4243:
4237:
4229:
4228:
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4216:
4208:
4207:
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4179:
4175:
4171:
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4165:
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4150:
4146:
4145:
4140:
4134:
4126:
4125:
4120:
4113:
4105:
4101:
4100:
4094:
4087:
4079:
4075:
4069:
4055:
4051:
4047:
4043:
4036:
4028:
4024:
4019:
4014:
4010:
4006:
4002:
3994:
3986:
3982:
3976:
3960:
3954:
3947:
3946:Press release
3942:
3927:
3921:
3913:
3909:
3904:
3899:
3895:
3891:
3887:
3883:
3879:
3875:
3871:
3864:
3862:
3846:
3842:
3836:
3822:
3818:
3812:
3798:
3794:
3790:
3789:
3784:
3777:
3775:
3760:on 2017-06-06
3759:
3755:
3749:
3741:
3735:
3721:on 2016-04-10
3720:
3716:
3712:
3706:
3692:on 2021-05-01
3691:
3687:
3683:
3677:
3669:
3665:
3659:
3651:
3650:
3645:
3639:
3631:
3630:
3625:
3619:
3611:
3610:
3605:
3599:
3591:
3587:
3582:
3577:
3572:
3567:
3563:
3559:
3555:
3548:
3540:
3536:
3531:
3526:
3522:
3518:
3514:
3507:
3499:
3495:
3490:
3485:
3480:
3475:
3471:
3467:
3466:
3461:
3454:
3446:
3440:
3436:
3432:
3431:
3423:
3408:
3404:
3397:
3382:
3378:
3372:
3364:
3360:
3355:
3350:
3347:(3): 388–91.
3346:
3342:
3338:
3331:
3323:
3317:
3312:
3311:
3302:
3295:
3294:9780470972458
3291:
3285:
3277:
3273:
3269:
3265:
3261:
3257:
3254:(3): 441–62.
3253:
3249:
3242:
3226:
3219:
3213:
3197:
3191:
3183:
3182:
3177:
3171:
3169:
3167:
3158:
3157:
3151:
3143:
3135:
3134:Fierce Pharma
3132:
3125:
3117:
3113:
3107:
3105:
3096:
3095:Goldman Sachs
3092:
3086:
3078:
3072:
3064:
3062:0-471-22878-8
3058:
3054:
3047:
3039:
3033:
3029:
3022:
3014:
3012:9780674396661
3008:
3004:
3003:
2995:
2987:
2980:
2972:
2968:
2964:
2958:
2950:
2949:
2944:
2938:
2930:
2924:
2920:
2916:
2915:
2907:
2905:
2903:
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2890:
2889:
2883:
2876:
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2872:
2857:
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2810:
2809:
2804:
2797:
2795:
2786:
2779:
2773:
2765:
2761:
2755:
2747:
2743:
2737:
2726:
2720:
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2673:Business Wire
2670:
2664:
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2653:
2649:
2644:
2639:
2634:
2629:
2625:
2621:
2618:(1): e30275.
2617:
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2607:
2600:
2592:
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2582:
2574:
2570:
2565:
2560:
2556:
2552:
2548:
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2543:
2538:
2531:
2523:
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2507:
2503:
2499:
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2475:
2471:
2467:
2463:
2459:
2456:(3): 154–65.
2455:
2451:
2447:
2440:
2432:
2431:Fierce Pharma
2428:
2421:
2407:on 2024-01-29
2406:
2402:
2398:
2392:
2384:
2383:
2378:
2372:
2364:
2360:
2354:
2346:
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2272:
2271:Business Wire
2268:
2262:
2254:
2250:
2246:
2245:
2239:
2231:
2223:
2219:
2213:
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2209:
2204:
2196:
2194:
2190:
2186:
2182:
2178:
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2171:
2170:AcademyHealth
2161:
2159:
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2142:
2138:
2134:
2130:
2120:
2117:
2113:
2103:
2095:
2093:
2089:
2084:
2082:
2078:
2072:
2069:
2065:
2060:
2055:
2053:
2049:
2045:
2035:
2032:
2027:
2023:
2019:
2009:
2005:
2002:
1998:
1994:
1990:
1980:
1978:
1973:
1971:
1965:
1961:
1957:
1955:
1952:
1947:
1942:
1940:
1935:
1933:
1929:
1925:
1921:
1917:
1913:
1910:In 1999, the
1898:
1896:
1892:
1888:
1884:
1880:
1876:
1866:
1858:
1856:
1846:
1837:
1835:
1830:
1805:
1799:
1793:
1787:
1780:
1777:
1776:
1774:
1768:
1762:
1756:
1749:ArQule, Inc.
1748:
1747:
1745:
1739:
1733:
1727:
1719:
1718:
1716:
1710:
1705:
1702:
1696:
1688:
1682:
1676:
1670:
1664:
1658:
1657:
1655:
1649:
1644:IOmet Pharma
1643:
1637:
1627:
1622:
1619:
1618:
1617:
1614:
1613:
1611:
1603:
1602:
1600:
1593:
1590:
1587:
1579:
1578:
1576:
1568:
1562:
1561:
1559:(Merged 1971)
1557:
1554:
1553:
1551:
1543:
1537:
1531:
1525:
1524:
1522:
1521:
1519:
1518:
1515:
1510:
1507:
1506:
1494:
1492:
1488:
1484:
1480:
1476:
1471:
1468:
1463:
1461:
1456:
1454:
1449:
1447:
1443:
1438:
1436:
1432:
1428:
1424:
1419:
1418:
1414:
1409:
1406:
1404:
1400:
1396:
1392:
1387:
1384:
1382:
1378:
1373:
1370:
1368:
1364:
1359:
1357:
1352:
1350:
1345:
1342:
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1336:
1331:
1329:
1325:
1320:
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1302:
1297:
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1291:
1289:
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1280:
1276:
1274:
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1265:
1263:
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1253:
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1200:
1198:
1193:
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1169:Richard Clark
1166:
1164:
1160:
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1148:
1147:Richard Clark
1144:
1140:
1137:
1132:
1130:
1129:
1124:
1119:
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1105:
1096:
1093:
1091:
1086:
1084:
1080:
1076:
1071:
1069:
1065:
1061:
1057:
1056:joint venture
1052:
1050:
1046:
1042:
1038:
1034:
1030:
1026:
1025:Satoshi Ōmura
1022:
1017:
1015:
1011:
1007:
1002:
1000:
999:John J. Horan
995:
993:
989:
985:
981:
977:
976:mumps vaccine
973:
969:
967:
963:
958:
956:
952:
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931:
928:
924:
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916:
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901:
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885:Goldman Sachs
882:
878:
877:expropriation
874:
864:
862:
856:
854:
850:
846:
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838:
835:in 1668 when
834:
830:
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809:
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792:
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787:
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781:
776:
775:
766:
762:
759:
756:
752:
749:
746:
743:
740:
736:
732:
729:
728:Pembrolizumab
725:
722:
719:
715:
712:
709:
705:
702:
699:
695:
691:
687:
683:
679:
675:
672:
669:
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663:
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651:
649:
645:
641:
637:
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622:
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614:
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602:
598:
594:
590:
586:
582:
578:
574:
570:
566:
562:
558:
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550:
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538:
537:pembrolizumab
534:
530:
526:
525:animal health
522:
518:
509:
500:
498:
494:
492:
487:
485:
479:
477:
473:
467:
465:
461:
457:
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449:
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445:multinational
442:
433:
429:
421:
415:
411:
405:
404:
402:
398:
393: 72,000
388:
382:
373:
370:
365:
356:
353:
348:
339:
336:
331:
322:
319:
314:
309:60.12 billion
308:
299:
295:
289:
286:
284:
281:
279:
276:
274:
271:
269:
266:
264:
263:generic drugs
261:
259:
256:
255:
253:
249:
244:
240:
236:
230:
224:
220:
214:
210:
207:
203:
196:
193:
192:
190:
186:
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166:
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150:
148:
144:
141:
138:
134:
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124:
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118:
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110:
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8356:
7924:Mallinckrodt
7809:Upsher-Smith
7671:
7640:Ortho-McNeil
7412:
7364:Merck family
7356:Merck family
7310:
7303:
7296:
7289:
7281:
7274:
7268:Publications
7229:Temozolomide
7128:Omarigliptin
7030:Subsidiaries
7011:Samuel Thier
7006:Anne Tatlock
7001:Thomas Shenk
6961:
6870:. Retrieved
6866:the original
6861:
6852:
6841:. Retrieved
6830:
6821:
6803:
6792:. Retrieved
6788:
6779:
6768:. Retrieved
6763:
6754:
6743:. Retrieved
6741:. 2021-02-03
6736:
6711:. Retrieved
6704:
6695:
6677:
6668:
6659:
6648:
6636:
6625:
6615:
6597:
6579:
6568:
6544:
6535:
6514:cite journal
6495:
6462:
6458:
6451:
6426:
6422:
6416:
6392:(4): 392–6.
6389:
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6358:
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6055:
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5892:
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5869:
5857:. Retrieved
5853:the original
5848:
5839:
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5801:
5792:The Guardian
5790:
5780:
5763:
5752:. Retrieved
5748:the original
5743:
5734:
5713:
5699:
5678:
5664:
5653:. Retrieved
5649:the original
5644:
5635:
5621:
5610:. Retrieved
5606:pharmaphorum
5605:
5596:
5585:
5575:
5563:. Retrieved
5554:
5544:
5530:
5512:
5494:
5483:
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5356:. Retrieved
5351:
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5322:
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5293:. Retrieved
5279:
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5236:. Retrieved
5231:
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5214:the original
5207:
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5172:
5162:
5154:the original
5147:
5138:
5120:
5102:
5094:the original
5087:
5077:
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2861:2021-06-24
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1796:(Acq 2023)
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1771:(Acq 2020)
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