862:
journal|last1=Hwang|first1=Ji-Sun|last2=Kim|first2=Song-Yi|last3=Jung|first3=Eun-Hye|last4=Kwon|first4=Mi-Youn|last5=Kim|first5=Kyoung-Hong|last6=Cho|first6=Hyeongjin|last7=Han|first7=Inn-Oc|date=2015-11-19|title=Exogenous Sodium
Pyruvate Stimulates Adipogenesis of 3T3-L1 Cells|journal=Journal of Cellular Biochemistry|volume=117|issue=1|pages=39–48|doi=10.1002/jcb.25244|pmid=26053972|s2cid=5100370 |issn=0730-2312}}</ref><ref>{{cite journal|last1=Fukushima|first1=Masamichi|last2=Lee|first2=Stefan M.|last3=Moro|first3=Nobuhiro|last4=Hovda|first4=David A.|last5=Sutton|first5=Richard L.|date=July 2009|title=Metabolic and Histologic Effects of Sodium Pyruvate Treatment in the Rat after Cortical Contusion Injury|journal=Journal of Neurotrauma|volume=26|issue=7|pages=1095–1110|doi=10.1089/neu.2008.0771|pmid=19594384|issn=0897-7151|pmc=2848946}}</ref>
820:'''Sodium pyruvate''' is a ] of the conjugate anion form of ], known as pyruvate. It is commonly added to cell culture media as an additional source of energy, but may also have protective effects against ]. This was reported by Giandomenico ''et al''.<ref>{{cite journal |vauthors=Giandomenico AR, Cerniglia GE, Biaglow JE, Stevens CW, Koch CJ | title = The importance of sodium pyruvate in assessing damage produced by hydrogen peroxide. | journal = Free Radic Biol Med| volume = 23 | issue = 3 | pages = 426–34 | year = 1997 | pmid = 9214579 | doi = 10.1016/S0891-5849(97)00113-5 | doi-access = free }}</ref> and has been confirmed by several independent groups.
841:
name=":0">{{cite journal|last1=Pandit|first1=Bijan|last2=Sarkar|first2=Abhijit|last3=Sinha|first3=Biswajit|date=2016|title=Solution thermodynamics of sodium pyruvate in aqueous glycine solutions at T 298.15-313.15 K|journal=Journal of the
Serbian Chemical Society|volume=81|issue=11|pages=1283–1294|doi=10.2298/jsc151031034p|issn=0352-5139|doi-access=free}}</ref> In the body, one way in which sodium pyruvate provides energy to cells is through pyruvate conversion to acetyl-CoA which then can enter the TCA cycle which produces energy and is linked to other energy producing processes.<ref name=":0" />
840:
Due to pyruvate being an intermediate in many pathways for metabolism including ], sodium pyruvate has been used in many experiments involving cell cultures to provide more energy. In adipocytes it was found that sodium pyruvate promoted increased uptake of insulin-mediated glucose.<ref
148:
70:
27:
861:
Along with having antioxidant properties and energy producing effects, sodium pyruvate has the ability to cross the blood-brain barrier and is used in several studies on brain injury because of these characteristics.<ref>{{cite
257:
Used lowercase "cite" template everywhere for consistency. Added the cs1 style template to denote
Vancouver ("vanc") citation style, because references contain "vauthors" attribute to specify the list of
144:
78:
84:
41:
35:
49:
92:
196:
287:{{ambox | text = This page contains a copy of the infobox ({{tl|chembox}}) taken from revid of page ] with values updated to verified values.}}
481:| OtherNames = {{bulletedlist|α-Ketopropionic acid sodium salt|2-Oxopropanoic acid sodium salt|Pyruvic acid sodium salt}}
16:
235:
228:
243:
206:
217:
210:
79:
166:
173:
239:
155:
50:
224:
177:
365:
333:
36:
701:| Formula = C<sub>3</sub>H<sub>3</sub>NaO<sub>3</sub>
93:
8:
162:
192:
119:
191:
Saving copy of the {{chembox}} taken from revid 444111851 of page
104:
103:
544:| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
537:| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
126:
468:| OtherNames = α-ketopropionic acid sodium salt
207:Latest revision as of 14:40, 24 January 2024
278:{{short description|Chemical compound}}
10:
571:| ChEMBL_Ref = {{ebicite|correct|EBI}}
371:
339:
145:Revision as of 15:54, 6 December 2011
69:
26:
625:| UNII_Ref = {{fdacite|correct|FDA}}
618:| UNII_Ref = {{fdacite|correct|FDA}}
135:
118:
448:| ImageNameR1 = The sodium cation
441:| ImageNameR1 = The sodium cation
408:| ImageFile = Sodium pyruvate.png
401:| ImageFile = Sodium pyruvate.png
300:{{cs1 config|name-list-style=vanc}}
255:
216:
204:
189:
154:
142:
14:
528:| Section1 = {{Chembox Identifiers
521:| Section1 = {{Chembox Identifiers
107:
924:
681:| Section2 = {{Chembox Properties
674:| Section2 = {{Chembox Properties
87:
73:
44:
30:
459:| PIN = Sodium 2-oxopropanoate
490:2-oxopropanoic acid sodium salt
197:Chem/Drugbox validation project
199:(updated: 'ChEMBL').
9:
1:
909:
900:
889:
878:
869:
857:
848:
836:
827:
816:
807:
746:
735:
708:
697:
688:
602:
592:
567:
506:
497:
486:
477:
464:
455:
353:
323:
296:
283:
274:
750:| SolubleOther = 100 mg/mL
739:| Solvent = other solvents
7:
712:| MolarMass = 110.0 g/mol
929:
692:| C=3 | H=3 | Na=1 | O=3
392:| Name = Sodium pyruvate
385:| Name = Sodium pyruvate
327:| Verifiedfields = changed
11:(Difference between pages)
907:
898:
887:
876:
867:
855:
846:
834:
825:
814:
805:
753:
742:
715:
704:
686:
649:
646:
565:
513:
502:
493:
475:
471:
453:
416:
413:
362:
357:| Watchedfields = changed
351:
347:
321:
294:
290:
272:
267:
264:
244:Pending changes reviewers
203:
141:
510:Pyruvic acid sodium salt
236:Extended confirmed users
140:
432:| ImageSizeR1 = 80px
425:| ImageSizeR1 = 80px
560:| ChemSpiderID = 7931
553:| ChemSpiderID = 7931
174:Edit filter managers
101:
58:
641:| UNII = POD38AIF08
634:| UNII = POD38AIF08
240:IP block exemptions
61:
18:
373:| verifiedrevid =
341:| verifiedrevid =
214:
152:
66:
23:
917:
784:| BoilingPt =}}
777:| BoilingPt =}}
587:| ChEMBL = 181886
580:| ChEMBL = 181886
205:
143:
89:
75:
62:
46:
32:
19:
920:
259:
250:
232:
213:
200:
184:
170:
151:
132:
131:
129:
124:
122:
114:
111:
105:
90:
76:
65:
47:
33:
22:
928:
927:
923:
922:
921:
919:
918:
914:
903:
894:
883:
872:
863:
851:
842:
830:
821:
810:
801:
794:
785:
778:
769:
768:| MeltingPt =
762:
761:| MeltingPt =
751:
740:
731:
724:
713:
702:
693:
682:
675:
666:
659:
642:
635:
626:
619:
610:
609:
600:
599:
588:
581:
572:
561:
554:
545:
538:
529:
522:
511:
500:
491:
482:
469:
460:
449:
442:
433:
426:
409:
402:
393:
386:
377:
376:
358:
345:
344:
328:
317:
310:
301:
288:
279:
260:
256:
254:
253:
252:
248:
246:
222:
220:
215:
209:
201:
193:Sodium_pyruvate
190:
188:
187:
186:
182:
180:
160:
158:
153:
147:
139:
138:
137:
136:
134:
133:
127:
125:
120:
117:
115:
112:
110:Content deleted
109:
106:
102:
100:
99:
98:
97:
96:
95:
94:
86:
83:
82:
81:
80:
72:
63:
59:
57:
56:
55:
54:
53:
52:
51:
43:
40:
39:
38:
37:
29:
20:
13:
12:
5:
926:
916:
915:
912:
910:
908:
905:
904:
901:
899:
896:
895:
892:
890:
888:
885:
884:
882:==References==
881:
879:
877:
874:
873:
870:
868:
865:
864:
860:
858:
856:
853:
852:
849:
847:
844:
843:
839:
837:
835:
832:
831:
828:
826:
823:
822:
819:
817:
815:
812:
811:
808:
806:
803:
802:
799:
797:
795:
792:
790:
787:
786:
783:
781:
779:
776:
774:
771:
770:
767:
765:
763:
760:
758:
755:
754:
752:
749:
747:
744:
743:
741:
738:
736:
733:
732:
729:
727:
725:
722:
720:
717:
716:
714:
711:
709:
706:
705:
703:
700:
698:
695:
694:
691:
689:
687:
684:
683:
680:
678:
676:
673:
671:
668:
667:
664:
662:
660:
657:
655:
652:
651:
648:
644:
643:
640:
638:
636:
633:
631:
628:
627:
624:
622:
620:
617:
615:
612:
611:
607:
605:
603:
601:
597:
595:
593:
590:
589:
586:
584:
582:
579:
577:
574:
573:
570:
568:
566:
563:
562:
559:
557:
555:
552:
550:
547:
546:
543:
541:
539:
536:
534:
531:
530:
527:
525:
523:
520:
518:
515:
514:
512:
509:
507:
504:
503:
501:
498:
495:
494:
492:
489:
487:
484:
483:
480:
478:
476:
473:
472:
470:
467:
465:
462:
461:
458:
456:
454:
451:
450:
447:
445:
443:
440:
438:
435:
434:
431:
429:
427:
424:
422:
419:
418:
415:
411:
410:
407:
405:
403:
400:
398:
395:
394:
391:
389:
387:
384:
382:
379:
378:
374:
370:
368:
363:
360:
359:
356:
354:
352:
349:
348:
346:
342:
338:
336:
330:
329:
326:
324:
322:
319:
318:
315:
313:
311:
308:
306:
303:
302:
299:
297:
295:
292:
291:
289:
286:
284:
281:
280:
277:
275:
273:
270:
269:
266:
262:
261:
247:
234:
233:
219:Maxim Masiutin
218:
202:
181:
178:Administrators
172:
171:
156:
116:
108:
91:
85:
77:
71:
68:
67:
60:
48:
42:
34:
28:
25:
24:
17:
15:
6:
4:
3:
2:
925:
911:
906:
902:
897:
891:
886:
880:
875:
871:
866:
859:
854:
850:
845:
838:
833:
829:
824:
818:
813:
809:
804:
798:
796:
791:
789:
788:
782:
780:
775:
773:
772:
766:
764:
759:
757:
756:
748:
745:
737:
734:
730:| Density =
728:
726:
723:| Density =
721:
719:
718:
710:
707:
699:
696:
690:
685:
679:
677:
672:
670:
669:
663:
661:
656:
654:
653:
645:
639:
637:
632:
630:
629:
623:
621:
616:
614:
613:
604:
594:
591:
585:
583:
578:
576:
575:
569:
564:
558:
556:
551:
549:
548:
542:
540:
535:
533:
532:
526:
524:
519:
517:
516:
508:
505:
499:
496:
488:
485:
479:
474:
466:
463:
457:
452:
446:
444:
439:
437:
436:
430:
428:
423:
421:
420:
412:
406:
404:
399:
397:
396:
390:
388:
383:
381:
380:
372:
369:
367:
364:
361:
355:
350:
340:
337:
335:
332:
331:
325:
320:
314:
312:
307:
305:
304:
298:
293:
285:
282:
276:
271:
263:
245:
241:
237:
230:
226:
221:
212:
208:
198:
194:
179:
175:
168:
164:
159:
150:
146:
130:
123:
113:Content added
606:| PubChem =
596:| PubChem =
893:{{reflist}}
88:Revision 2
45:Revision 1
375:464403469
343:444110012
316:{{chembox
309:{{chembox
650:Line 36:
647:Line 34:
608:23662274
417:Line 13:
414:Line 10:
366:⚫
334:⚫
258:authors.
229:contribs
195:for the
167:contribs
157:Beetstra
128:Wikitext
268:Line 1:
265:Line 1:
183:171,922
249:30,010
121:Visual
74:Page 2
64:Page 2
31:Page 1
21:Page 1
251:edits
185:edits
598:8224
225:talk
211:edit
163:talk
149:edit
800:}}
793:}}
665:}}
658:}}
242:,
238:,
227:|
176:,
165:|
913:]
231:)
223:(
169:)
161:(
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.