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In 2001, Lanza initiated a letter to US president G.W.Bush, urging him to not block the first flow of federal dollars for research on human embryo cells. The letter was signed by 80 Nobel laureates from various areas of science and send to the White House by FAX, three weeks before a deadline to
407:(a population of "ambulance" cells) from human embryonic stem cells. In animals, these cells quickly repaired vascular damage, cutting the death rate after a heart attack in half and restoring the blood flow to ischemic limbs that might otherwise have required amputation.
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asserted that Lanza's concept was a "...vague, inarticulate metaphor..." and stated that "...I certainly don't see how thinking his way would lead you into any new sort of scientific or philosophical insight. That's all very nice, I would say to Lanza, but now what?"
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The results of the first two clinical trials were published in the Lancet in 2012, with a follow-up paper in 2014, which provided the first published reports of the long-term safety and possible biologic activity of pluripotent stem cell progeny into humans.
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Lund, R. D.; Wang, S.; Klimanskaya, I.; Holmes, T.; Ramos-Kelsey, R.; Lu, B.; Girman, S.; Bischoff, N.; Sauvé, Y.; Lanza, R. (29 September 2006). "Human
Embryonic Stem Cell–Derived Cells Rescue Visual Function in Dystrophic RCS Rats – Cloning Stem Cells".
395:
Lanza and his colleagues were the first to demonstrate that nuclear transplantation could be used to extend the lifespan of certain cells and to generate immune-compatible tissues, including the first organ grown in the laboratory from cloned cells.
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Lanza showed that it is feasible to generate functional oxygen-carrying red blood cells from human embryonic stem cells under conditions suitable for clinical scale-up. The blood cells could potentially serve as a source of "universal" blood.
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stated that "Any short statement does not do justice to such a scholarly work. The work is a scholarly consideration of science and philosophy that brings biology into the central role in unifying the whole." Former
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stated: "There are no scientific breakthroughs about anything, as far as I can see. It may represent interesting philosophy, but it doesn't look, at first glance, as if it will change anything about science." In
548:, said he did not think the concept meets the standard of a philosophical theory. "It looks like an opposite of a theory, because he doesn't explain how happens at all. He's stopping where the fun begins."
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2250:"Advanced Cell Technology's Chief Scientific Officer Dr. Robert Lanza Honored By BioWorld Magazine As Leader Who Could Shape Biotech Over Next 20 Years Dr. Lanza Recognized as a "Stem Cell Pioneer""
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to use its PSC-based cell therapy in the UK; this was the first approval to study a PSC-based treatment in Europe. The first person received the embryonic stem cell treatment in the UK in 2012.
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Schwartz, SD; et al. (15 October 2014). "Human embryonic stem cell-derived retinal pigment epithelium in patients with age-related macular degeneration and
Stargardt's macular dystrophy".
2223:
358:
Lanza was part of the team that cloned the world's first early stage human embryos, as well as the first to successfully generate stem cells from adults using somatic-cell nuclear transfer (
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576:. Lanza said in an interview that he wanted "to bring to life" in a story that would explain that "space, time, and the nature of life and death itself depends on the observer in us."
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685:(publication) hailed Lanza as a "stem cell pioneer" and recognized him as one of twenty-eight "movers and shakers" who would shape biotechnology over the next twenty years
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cells from stem cells, and subsequent studies found that these cells could restore vision in animal models of macular degeneration. With this technology, some forms of
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reported a method for generating induced pluripotent stem (iPS) cells by incubating them with proteins, instead of genetically manipulating the cells to
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for clinical trials of a pluripotent stem cell-based treatment for use in people with degenerative eye diseases. In 2011 ACT received approval from the
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2013: nominated to receive the
Italian Heritage and Culture Committee of the Bronx and Westchester "Il Leone di San Marco Award in Medicine"
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Schwartz, SD; et al. (25 February 2012). "Embryonic stem cell trials for macular degeneration: a preliminary report".
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Lanza subsequently published several books that further developed his concept of biocentrism including a 2016 book,
325:, receiving BA and MD degrees. There, he was a Benjamin Franklin Scholar and a University Scholar. Lanza was also a
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2018:
1417:"Cell Stem Cell - Generation of Human Induced Pluripotent Stem Cells by Direct Delivery of Reprogramming Proteins"
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Klimanskaya, Irina; et al. (2006). "Human embryonic stem cell lines derived from single blastomeres".
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Lu, SJ; Feng, Q; Park, JS; Vida, L; Lee, BS; Strausbauch, M; Wettstein, PJ; Honig, GR; Lanza, R (2008).
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26:
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1882:"A New Theory of the Universe: Biocentrism builds on quantum physics by putting life into the equation"
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1991:
Biocentrism: How Life and
Consciousness Are the Keys to Understanding the True Nature of the Universe
532:
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2310:"Advanced Cell Technology's Dr. Robert Lanza to Receive the Il Leone di San Marco Award in Medicine"
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688:
2010: for research in "translating basic science discoveries into new and better treatments"; won a
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Biocentrism, How Life and
Consciousness are the Keys to Understandin the True Nature of the Universe
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275:
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545:
2141:"Sci-fi author and scientist team up to write a novel about consciousness and quantum weirdness"
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Lanza, Robert P. (2002). "Generation of histocompatible tissues using nuclear transplantation".
1114:"Extension of Cell Life-Span and Telomere Length in Animals Cloned from Senescent Somatic Cells"
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Lu, S. J.; Feng, Q.; Caballero, S.; Chen, Y.; Moore, M. A.; Grant, M. B.; Lanza, R. (2007).
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to revise the decision of the
Clinton administration to generously fund stem cell research.
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8:
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2169:"[Q&A]: PW Talks with Robert Lanza and Nancy Kress: I See, Therefore You Are"
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305:. Lanza "altered the genetics of chickens in his basement", and came to the attention of
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1209:"Blood - Biological properties and enucleation of red blood cells from human embryoni"
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Beyond
Biocentrism: Rethinking Time, Space, Consciousness, and the Illusion of Death
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Beyond
Biocentrism, Rethinking Time, Space, Consciousness, and the Illusion of Death
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Beyond
Biocentrism: Rethinking Time, Space, Consciousness, and the Illusion of Death
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apply for NIH stem cell research grants. This was in view of the intention by the
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Biocentrism: How Life and
Consciousness are the Keys to Understanding the Universe
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1685:"Stem cell scientists take hope from first human trials but see long road ahead"
2336:"ACT's Dr. Robert Lanza to Receive the Il Leone di San Marco Award in Medicine"
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1628:"First trial of embryonic stem cell treatment in Europe gets green light"
1309:"Generation of functional hemangioblasts from human embryonic stem cells"
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2006: named "Mass High Tech All Star" at the 11th annual award reception
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Lanza was born in Boston, Massachusetts, and grew up south of there, in
2224:"Thought Leaders: Robert Lanza on stem cells and access to health care"
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1986:
768:"Ocata's chief scientific officer to join new parent after acquisition"
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Lanza has received numerous awards and other recognition, including:
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Perelman School of Medicine at the University of Pennsylvania alumni
2197:"Dr. Robert Lanza Receives 2006 'All Star' Award For Biotechnology"
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In 2007 Lanza's article "A New Theory of the Universe" appeared in
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In 2001, he was also the first to clone an endangered species (a
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researchers when he appeared at the university with his results.
216:
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In January 2023, Lanza published a novel exploring biocentrism,
2435:
1258:"Transfusion breakthrough as human blood grown from stem cells"
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Lanza's team at Advanced Cell Technology were able to generate
388:) from the frozen skin cells of an animal that had died at the
274:, currently Head of Astellas Global Regenerative Medicine, and
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486:, which places biology above the other sciences. Lanza's book
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1656:"First European Embryonic Stem Cell Trial Gets Green Light"
793:"Wake Forest University School of Medicine Adjunct Faculty"
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mentored Lanza over the next ten years. Lanza attended the
1599:"Second human embryonic stem cell clinical trial to start"
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Lanza's biocentric hypothesis met with a mixed reception.
51:
to this revision, which may differ significantly from the
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944:"Human somatic cell nuclear transfer using adult cells"
2369:"Time: The 100 Most Influential People - Robert Lanza"
1281:"Elusive 'ambulance' cells are created - USATODAY.com"
861:
708:
list of the "100 Most Influential People in the World"
53:
2109:
The Grand Biocentric Design: How Life Creates Reality
641:
The Grand Biocentric Design, How Life Creates Reality
557:
The Grand Biocentric Design: How Life Creates Reality
1545:"Two Patients Undergo Stem-Cell Blindness Treatment"
559:, written with Bob Berman and theoretical physicist
2280:"Stem cell leaders Lanza, Kim win $ 1.9M NIH award"
1306:
1219:(12). Bloodjournal.hematologylibrary.org: 4475–84.
447:
Medicines and Healthcare products Regulatory Agency
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371:embryonic stem cells without embryonic destruction
985:"Scientists Make First Embryo Clones From Adults"
2454:
2449:: blog, and archive of books, articles and news.
1571:"FDA Approves Second Trial of Stem-Cell Therapy"
1358:"Researchers Hail Stem Cells Safe for Human Use"
425:
1804:"Stem Cells Allow Nearly Blind Patients to See"
1112:Lanza, Robert P.; et al. (28 April 2000).
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403:His team discovered how to generate functional
1980:
1978:
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242:Astellas Institute for Regenerative Medicine,
2045:"Exclusive: Response to Robert Lanza's essay"
1391:"Stem-Cell Trial Without Embryo Destruction"
717:magazine list of the "Top 50 World Thinkers"
280:Astellas Institute for Regenerative Medicine
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1984:
1975:
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365:Lanza demonstrated that techniques used in
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1931:"Cosmic Log: Theory of Every-Living-Thing"
1901:
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797:Wake Forest University: School of Medicine
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146:
112:
2177:. Vol. 269, no. 50. p. 31.
1832:"Nobel Laureates Back Stem Cell Research"
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1232:
1061:"Cloning Noah's Ark: Scientific American"
959:
244:Wake Forest University School of Medicine
743:"A Biotech Provocateur Takes On Physics"
441:In 2010, ACT received approval from the
340:
61:Revision as of 11:00, 4 January 2024 by
2221:
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482:. The essay proposed Lanza's idea of a
392:nearly a quarter-of-a-century earlier.
60:
14:
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1625:
1389:Rockoff, Jonathan (13 December 2012).
942:Chung, Young Gie; et al. (2014).
2135:
2129:
1879:
1163:
915:"Wired 12.01: Seven Days of Creation"
817:Fischer, Joannie (25 November 2001).
353:
131:American medical doctor and scientist
44:
25:
2366:
2260:from the original on 17 January 2021
1355:
982:
866:; Ezzell, Carol (24 November 2001).
862:Cibelli, Jose B.; Lanza, Robert P.;
588:
17:
2401:"World Thinkers 2015: Robert Lanza"
2344:. 24 September 2013. Archived from
2286:. 22 September 2010. Archived from
1521:. 24 September 2004. Archived from
1414:
466:Health and Human Services Secretary
111:
80:
2381:from the original on 25 April 2014
2167:Picker, Lenny (28 November 2022).
1904:"Will Biology Solve the Universe?"
1256:Henderson, Mark (20 August 2008).
740:
692:(NIH) Director's Opportunity Award
490:followed in 2009, co-written with
129:
2499:
2428:
2413:from the original on 4 April 2015
1626:Sample, Ian (22 September 2011).
886:10.1038/scientificamerican0102-44
367:preimplantation genetic diagnosis
47:. The present address (URL) is a
2434:
2226:. Mass High Tech. Archived from
2222:Songini, Marc (14 August 2009).
1957:"Robert Lanza - Tag Story Index"
1745:
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438:could potentially be treatable.
410:In 2012 Lanza and a team led by
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1513:"Stem Cells May Open Some Eyes"
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868:"The First Human Cloned Embryo"
662:(The Story Plant, 2023) – with
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2468:Wake Forest University faculty
1880:Lanza, Robert (1 March 2007).
1683:Boseley, Sarah (4 June 2012).
1002:
983:Naik, Gautam (17 April 2014).
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935:
907:
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13:
1:
2367:Park, Alice (23 April 2014).
1902:Aaron Rowe (4 January 2009).
1774:10.1016/S0140-6736(14)61376-3
1724:10.1016/S0140-6736(12)60028-2
721:
690:National Institutes of Health
426:Clinical trials for blindness
126:, was based on this revision.
2183:'s Business Source Complete
1933:. Cosmic Log. Archived from
1225:10.1182/blood-2008-05-157198
1143:10.1126/science.288.5466.665
824:U.S. News & World Report
670:Awards and public commentary
572:with science fiction author
443:Food and Drug Administration
432:retinal pigmented epithelium
7:
2019:"The universe in your head"
1356:Park, Alice (28 May 2009).
1279:Vergano, Dan (8 May 2007).
345:Lanza being interviewed by
24:of this page, as edited by
10:
2504:
1433:10.1016/j.stem.2009.05.005
961:10.1016/j.stem.2014.03.015
954:(6). Cell Press: 777–780.
499:Nobel laureate in medicine
369:could be used to generate
329:. He currently resides in
323:University of Pennsylvania
258:(born 11 February 1956 in
203:University of Pennsylvania
563:, and published in 2020.
384:an endangered wild ox (a
336:
249:
238:
231:
208:
198:
190:
157:
145:
138:
2483:American science writers
831:(23): 50–4, 57–8, 60–3.
637:(2016) – with Bob Berman
507:Arizona State University
303:Stoughton, Massachusetts
297:Early life and education
276:Chief Scientific Officer
2185:(subscription required)
989:The Wall Street Journal
546:eliminative materialist
458:Science policy activism
2179: – via
1861:Check date values in:
1483:10.1089/clo.2006.8.189
1467:Cloning and Stem Cells
711:2015: included in the
698:2014: included in the
350:
331:Clinton, Massachusetts
307:Harvard Medical School
288:Wake Forest University
2488:Stem cell researchers
344:
45:11:00, 4 January 2024
2443:at Wikimedia Commons
2409:. 16 February 2015.
2290:on 25 September 2010
2107:(17 November 2020).
1887:The American Scholar
1415:Kim, Dohoon (2009).
1268:on 20 November 2008.
1166:Nature Biotechnology
479:The American Scholar
2316:. 24 September 2013
1837:The Washington Post
1664:. 22 September 2011
1395:Wall Street Journal
1135:2000Sci...288..665L
1065:Scientific American
1031:10.1038/nature05142
1023:2006Natur.444..481K
873:Scientific American
484:biocentric universe
422:of those proteins.
380:), and in 2003, he
360:therapeutic cloning
226:biocentric universe
87:← Previous revision
2348:on 16 January 2016
2139:(9 January 2023).
1945:– via MSNBC.
1863:|access-date=
1840:. 22 February 2001
1607:. 22 November 2010
1579:. 22 November 2010
1087:"Wild Cows Cloned"
1067:. 19 November 2000
604:. You can help by
416:Harvard University
354:Stem cell research
351:
319:Christiaan Barnard
291:School of Medicine
222:tissue engineering
2439:Media related to
2230:on 15 August 2009
2203:. 24 October 2006
2174:Publishers Weekly
2004:978-1-933771-69-4
1989:(14 April 2009).
1963:. 16 October 2008
1892:Spring 2007 issue
1812:. 14 October 2014
1549:Technology Review
1525:on 15 August 2009
1325:10.1038/nmeth1041
1129:(5466): 665–669.
1017:(7118): 481–485.
843:on 26 August 2008
819:"The First Clone"
741:Herper, Matthew.
622:
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502:E. Donnall Thomas
327:Fulbright Scholar
284:Adjunct Professor
266:) is an American
253:
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233:Scientific career
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544:philosopher and
542:Tufts University
521:USA Today Online
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172:11 February 1956
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116:accepted version
99:Newer revision →
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2103:Lanza, Robert;
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2070:Lanza, Robert;
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1985:Lanza, Robert;
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2072:Berman, Bob
2029:14 December
1987:Berman, Bob
777:24 February
664:Nancy Kress
585:Non-fiction
574:Nancy Kress
472:Biocentrism
282:. He is an
191:Nationality
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1477:: 189–99.
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722:References
630:Bob Berman
613:April 2023
511:antitheist
492:Bob Berman
311:Jonas Salk
168:1956-02-11
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1961:USA Today
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