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In 2001, Lanza initiated a letter to US president G.W.Bush, urging him to not block the first flow of federal dollars for research on human embryo cells. The letter was signed by 80 Nobel laureates from various areas of science and send to the White House by FAX, three weeks before a deadline to
565:(a population of "ambulance" cells) from human embryonic stem cells. In animals, these cells quickly repaired vascular damage, cutting the death rate after a heart attack in half and restoring the blood flow to ischemic limbs that might otherwise have required amputation. 693:
asserted that Lanza's concept was a "...vague, inarticulate metaphor..." and stated that "...I certainly don't see how thinking his way would lead you into any new sort of scientific or philosophical insight. That's all very nice, I would say to Lanza, but now what?"
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The results of the first two clinical trials were published in the Lancet in 2012, with a follow-up paper in 2014, which provided the first published reports of the long-term safety and possible biologic activity of pluripotent stem cell progeny into humans.
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Lund, R. D.; Wang, S.; Klimanskaya, I.; Holmes, T.; Ramos-Kelsey, R.; Lu, B.; Girman, S.; Bischoff, N.; Sauvé, Y.; Lanza, R. (29 September 2006). "Human Embryonic Stem Cell–Derived Cells Rescue Visual Function in Dystrophic RCS Rats – Cloning Stem Cells".
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Lanza and his colleagues were the first to demonstrate that nuclear transplantation could be used to extend the lifespan of certain cells and to generate immune-compatible tissues, including the first organ grown in the laboratory from cloned cells.
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Lanza showed that it is feasible to generate functional oxygen-carrying red blood cells from human embryonic stem cells under conditions suitable for clinical scale-up. The blood cells could potentially serve as a source of "universal" blood.
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stated that "Any short statement does not do justice to such a scholarly work. The work is a scholarly consideration of science and philosophy that brings biology into the central role in unifying the whole." Former
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stated: "There are no scientific breakthroughs about anything, as far as I can see. It may represent interesting philosophy, but it doesn't look, at first glance, as if it will change anything about science." In
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to use its PSC-based cell therapy in the UK; this was the first approval to study a PSC-based treatment in Europe. The first person received the embryonic stem cell treatment in the UK in 2012.
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Schwartz, SD; et al. (15 October 2014). "Human embryonic stem cell-derived retinal pigment epithelium in patients with age-related macular degeneration and Stargardt's macular dystrophy".
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Lanza was part of the team that cloned the world's first early stage human embryos, as well as the first to successfully generate stem cells from adults using somatic-cell nuclear transfer (
2416: 734:. Lanza said in an interview that he wanted "to bring to life" in a story that would explain that "space, time, and the nature of life and death itself depends on the observer in us." 2446: 1989: 843:(publication) hailed Lanza as a "stem cell pioneer" and recognized him as one of twenty-eight "movers and shakers" who would shape biotechnology over the next twenty years 592:
cells from stem cells, and subsequent studies found that these cells could restore vision in animal models of macular degeneration. With this technology, some forms of
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reported a method for generating induced pluripotent stem (iPS) cells by incubating them with proteins, instead of genetically manipulating the cells to
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for clinical trials of a pluripotent stem cell-based treatment for use in people with degenerative eye diseases. In 2011 ACT received approval from the
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2013: nominated to receive the Italian Heritage and Culture Committee of the Bronx and Westchester "Il Leone di San Marco Award in Medicine"
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Schwartz, SD; et al. (25 February 2012). "Embryonic stem cell trials for macular degeneration: a preliminary report".
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Lanza subsequently published several books that further developed his concept of biocentrism including a 2016 book,
483:, receiving BA and MD degrees. There, he was a Benjamin Franklin Scholar and a University Scholar. Lanza was also a 1142: 2155: 1575:"Cell Stem Cell - Generation of Human Induced Pluripotent Stem Cells by Direct Delivery of Reprogramming Proteins" 262:*''Beyond Biocentrism, Rethinking Time, Space, Consciousness, and the Illusion of Death'' (2016) – with Bob Berman 255:*''Beyond Biocentrism, Rethinking Time, Space, Consciousness, and the Illusion of Death'' (2016) – with Bob Berman 2023: 1218: 635: 2537: 150: 100: 2624: 1842: 122: 2577: 998: 847: 2277: 1423: 1548: 1167:
Klimanskaya, Irina; et al. (2006). "Human embryonic stem cell lines derived from single blastomeres".
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Lu, SJ; Feng, Q; Park, JS; Vida, L; Lee, BS; Strausbauch, M; Wettstein, PJ; Honig, GR; Lanza, R (2008).
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Biocentrism: How Life and Consciousness Are the Keys to Understanding the True Nature of the Universe
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Biocentrism, How Life and Consciousness are the Keys to Understanding the True Nature of the Universe
690: 2515: 2447:"Advanced Cell Technology's Dr. Robert Lanza to Receive the Il Leone di San Marco Award in Medicine" 1904: 846:
2010: for research in "translating basic science discoveries into new and better treatments"; won a
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Lanza, Robert P. (2002). "Generation of histocompatible tissues using nuclear transplantation".
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Lu, S. J.; Feng, Q.; Caballero, S.; Chen, Y.; Moore, M. A.; Grant, M. B.; Lanza, R. (2007).
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to revise the decision of the Clinton administration to generously fund stem cell research.
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Beyond Biocentrism: Rethinking Time, Space, Consciousness, and the Illusion of Death
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Beyond Biocentrism, Rethinking Time, Space, Consciousness, and the Illusion of Death
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Beyond Biocentrism: Rethinking Time, Space, Consciousness, and the Illusion of Death
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apply for NIH stem cell research grants. This was in view of the intention by the
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Biocentrism: How Life and Consciousness are the Keys to Understanding the Universe
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2006: named "Mass High Tech All Star" at the 11th annual award reception
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Lanza was born in Boston, Massachusetts, and grew up south of there, in
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Lanza has received numerous awards and other recognition, including:
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Perelman School of Medicine at the University of Pennsylvania alumni
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In 2007 Lanza's article "A New Theory of the Universe" appeared in
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In 2001, he was also the first to clone an endangered species (a
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researchers when he appeared at the university with his results.
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In January 2023, Lanza published a novel exploring biocentrism,
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Lanza's team at Advanced Cell Technology were able to generate
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mentored Lanza over the next ten years. Lanza attended the
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Lanza's biocentric hypothesis met with a mixed reception.
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list of the "100 Most Influential People in the World"
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The Grand Biocentric Design: How Life Creates Reality
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The Grand Biocentric Design, How Life Creates Reality
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The Grand Biocentric Design: How Life Creates Reality
1703:"Two Patients Undergo Stem-Cell Blindness Treatment" 717:, written with Bob Berman and theoretical physicist 2417:"Stem cell leaders Lanza, Kim win $ 1.9M NIH award" 1464: 1377:(12). Bloodjournal.hematologylibrary.org: 4475–84. 605:
Medicines and Healthcare products Regulatory Agency
2200: 529:embryonic stem cells without embryonic destruction 1143:"Scientists Make First Embryo Clones From Adults" 246:the True Nature of the Universe'' (2009) – with ] 235:the True Nature of the Universe'' (2009) – with ] 2591: 2586:: blog, and archive of books, articles and news. 1729:"FDA Approves Second Trial of Stem-Cell Therapy" 1516:"Researchers Hail Stem Cells Safe for Human Use" 583: 1962:"Stem Cells Allow Nearly Blind Patients to See" 1270:Lanza, Robert P.; et al. (28 April 2000). 827: 561:His team discovered how to generate functional 2117: 2115: 1364: 400:Astellas Institute for Regenerative Medicine, 2182:"Exclusive: Response to Robert Lanza's essay" 1549:"Stem-Cell Trial Without Embryo Destruction" 875:magazine list of the "Top 50 World Thinkers" 438:Astellas Institute for Regenerative Medicine 2239: 2206: 2121: 2112: 968: 523:Lanza demonstrated that techniques used in 454: 2068:"Cosmic Log: Theory of Every-Living-Thing" 2038: 1861: 1013: 955:Wake Forest University: School of Medicine 614: 304: 27: 2314:. Vol. 269, no. 50. p. 31. 1990:"Nobel Laureates Back Stem Cell Research" 1598: 1490: 1413: 1390: 1219:"Cloning Noah's Ark: Scientific American" 1117: 402:Wake Forest University School of Medicine 901:"A Biotech Provocateur Takes On Physics" 599:In 2010, ACT received approval from the 498: 285:Latest revision as of 07:52, 29 May 2024 151:Latest revision as of 07:52, 29 May 2024 28: 2358: 2010: 1840: 1546: 1436: 974: 640:. The essay proposed Lanza's idea of a 550:nearly a quarter-of-a-century earlier. 2592: 2303: 2297: 1783: 1547:Rockoff, Jonathan (13 December 2012). 1100:Chung, Young Gie; et al. (2014). 168:2603:8000:d300:3650:ad45:e6ee:7a8:8b7c 2272: 2266: 2016: 1321: 1073:"Wired 12.01: Seven Days of Creation" 975:Fischer, Joannie (25 November 2001). 511: 289:American medical doctor and scientist 2503: 2397:from the original on 17 January 2021 1513: 1140: 1024:; Ezzell, Carol (24 November 2001). 1020:Cibelli, Jose B.; Lanza, Robert P.; 746: 101:Revision as of 11:06, 4 January 2024 91: 57: 2538:"World Thinkers 2015: Robert Lanza" 2481:. 24 September 2013. Archived from 2423:. 22 September 2010. Archived from 1679:. 24 September 2004. Archived from 1572: 624:Health and Human Services Secretary 179: 165: 148: 141: 136: 110: 98: 13: 2518:from the original on 25 April 2014 2304:Picker, Lenny (28 November 2022). 2041:"Will Biology Solve the Universe?" 1414:Henderson, Mark (20 August 2008). 898: 850:(NIH) Director's Opportunity Award 648:followed in 2009, co-written with 287: 222:{{Expand section|date=April 2023}} 215:{{Expand section|date=April 2023}} 46: 2636: 2565: 2550:from the original on 4 April 2015 1784:Sample, Ian (22 September 2011). 1044:10.1038/scientificamerican0102-44 525:preimplantation genetic diagnosis 2571: 2363:. Mass High Tech. Archived from 2359:Songini, Marc (14 August 2009). 2094:"Robert Lanza - Tag Story Index" 1903: 750: 596:could potentially be treatable. 568:In 2012 Lanza and a team led by 383: 2530: 2497: 2465: 2439: 2409: 2379: 2352: 2326: 2174: 2148: 2086: 2060: 2032: 1982: 1954: 1911: 1834: 1806: 1777: 1749: 1721: 1695: 1671:"Stem Cells May Open Some Eyes" 1663: 1615: 1566: 1540: 1507: 1458: 1430: 1407: 1358: 1315: 1263: 1237: 1211: 1026:"The First Human Cloned Embryo" 820:(The Story Plant, 2023) – with 737: 2605:Wake Forest University faculty 2017:Lanza, Robert (1 March 2007). 1841:Boseley, Sarah (4 June 2012). 1160: 1141:Naik, Gautam (17 April 2014). 1134: 1093: 1065: 943: 918: 629: 1: 2504:Park, Alice (23 April 2014). 2039:Aaron Rowe (4 January 2009). 1932:10.1016/S0140-6736(14)61376-3 1882:10.1016/S0140-6736(12)60028-2 879: 848:National Institutes of Health 584:Clinical trials for blindness 283: 238: 227: 2320:'s Business Source Complete 2070:. Cosmic Log. Archived from 1383:10.1182/blood-2008-05-157198 1301:10.1126/science.288.5466.665 982:U.S. News & World Report 828:Awards and public commentary 730:with science fiction author 601:Food and Drug Administration 590:retinal pigmented epithelium 18:Browse history interactively 7: 2156:"The universe in your head" 1514:Park, Alice (28 May 2009). 1437:Vergano, Dan (8 May 2007). 503:Lanza being interviewed by 10: 2641: 1591:10.1016/j.stem.2009.05.005 1119:10.1016/j.stem.2014.03.015 1112:(6). Cell Press: 777–780. 657:Nobel laureate in medicine 527:could be used to generate 487:. He currently resides in 481:University of Pennsylvania 416:(born 11 February 1956 in 361:University of Pennsylvania 721:, and published in 2020. 542:an endangered wild ox (a 494: 407: 396: 389: 366: 356: 348: 315: 303: 296: 190: 187: 147: 97: 2620:American science writers 989:(23): 50–4, 57–8, 60–3. 795:(2016) – with Bob Berman 665:Arizona State University 461:Stoughton, Massachusetts 455:Early life and education 434:Chief Scientific Officer 2322:(subscription required) 1147:The Wall Street Journal 704:eliminative materialist 616:Science policy activism 96: 2316: – via  1641:10.1089/clo.2006.8.189 1625:Cloning and Stem Cells 869:2015: included in the 856:2014: included in the 508: 489:Clinton, Massachusetts 465:Harvard Medical School 446:Wake Forest University 2625:Stem cell researchers 502: 2580:at Wikimedia Commons 2546:. 16 February 2015. 2427:on 25 September 2010 2244:(17 November 2020). 2024:The American Scholar 1573:Kim, Dohoon (2009). 1426:on 20 November 2008. 1324:Nature Biotechnology 637:The American Scholar 2453:. 24 September 2013 1995:The Washington Post 1822:. 22 September 2011 1553:Wall Street Journal 1293:2000Sci...288..665L 1223:Scientific American 1189:10.1038/nature05142 1181:2006Natur.444..481K 1031:Scientific American 642:biocentric universe 580:of those proteins. 538:), and in 2003, he 518:therapeutic cloning 384:biocentric universe 2485:on 16 January 2016 2276:(9 January 2023). 2082:– via MSNBC. 1998:. 22 February 2001 1765:. 22 November 2010 1737:. 22 November 2010 1245:"Wild Cows Cloned" 1225:. 19 November 2000 762:. You can help by 574:Harvard University 512:Stem cell research 509: 477:Christiaan Barnard 449:School of Medicine 380:tissue engineering 163: 108: 2576:Media related to 2367:on 15 August 2009 2340:. 24 October 2006 2311:Publishers Weekly 2141:978-1-933771-69-4 2126:(14 April 2009). 2100:. 16 October 2008 2029:Spring 2007 issue 1970:. 14 October 2014 1707:Technology Review 1683:on 15 August 2009 1483:10.1038/nmeth1041 1287:(5466): 665–669. 1175:(7118): 481–485. 1001:on 26 August 2008 977:"The First Clone" 899:Herper, Matthew. 780: 779: 660:E. Donnall Thomas 485:Fulbright Scholar 442:Adjunct Professor 424:) is an American 411: 410: 391:Scientific career 282: 149: 99: 79: 39: 2632: 2584:Personal website 2575: 2560: 2559: 2557: 2555: 2534: 2528: 2527: 2525: 2523: 2501: 2495: 2494: 2492: 2490: 2469: 2463: 2462: 2460: 2458: 2443: 2437: 2436: 2434: 2432: 2413: 2407: 2406: 2404: 2402: 2383: 2377: 2376: 2374: 2372: 2356: 2350: 2349: 2347: 2345: 2330: 2324: 2323: 2315: 2301: 2295: 2294: 2292: 2290: 2270: 2264: 2263: 2237: 2231: 2230: 2204: 2198: 2197: 2195: 2193: 2178: 2172: 2171: 2169: 2167: 2152: 2146: 2145: 2119: 2110: 2109: 2107: 2105: 2090: 2084: 2083: 2081: 2079: 2074:on 12 March 2007 2064: 2058: 2057: 2055: 2053: 2036: 2030: 2028: 2014: 2008: 2007: 2005: 2003: 1986: 1980: 1979: 1977: 1975: 1958: 1952: 1951: 1926:(9967): 509–16. 1915: 1909: 1908: 1907: 1901: 1876:(9817): 713–20. 1865: 1859: 1858: 1856: 1854: 1838: 1832: 1831: 1829: 1827: 1810: 1804: 1803: 1801: 1799: 1781: 1775: 1774: 1772: 1770: 1753: 1747: 1746: 1744: 1742: 1725: 1719: 1718: 1716: 1714: 1699: 1693: 1692: 1690: 1688: 1667: 1661: 1660: 1633:Mary Ann Liebert 1619: 1613: 1612: 1602: 1570: 1564: 1563: 1561: 1559: 1544: 1538: 1537: 1535: 1533: 1524:. 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