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Triazolam

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including triazolam, the nonbenzodiazepine sedative-hypnotics appeared to offer few, if any, significant clinical advantages in efficacy or tolerability in elderly persons. Newer agents with novel mechanisms of action and improved safety profiles, such as the melatonin agonists, hold promise for the management of chronic insomnia in elderly people. Long-term use of sedative-hypnotics for insomnia lacks an evidence base and has traditionally been discouraged for reasons that include concerns about such potential adverse drug effects as cognitive impairment, anterograde amnesia, daytime sedation, motor incoordination, and increased risk of motor vehicle accidents and falls. One study found no evidence of sustained hypnotic efficacy throughout the 9 weeks of treatment for triazolam.
626: 603: 47: 38: 7788: 1754: 1028:, causes impairments in body balance and standing steadiness in individuals who wake up at night or the next morning. Falls and hip fractures are frequently reported. The combination with alcohol increases these impairments. Partial, but incomplete tolerance develops to these impairments. Daytime withdrawal effects can occur. 854:
Triazolam is frequently prescribed as a sleep aid for passengers travelling on short- to medium-duration flights. If this use is contemplated, the user avoiding the consumption of alcoholic beverages is especially important, as is trying a ground-based "rehearsal" of the medication to ensure that
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An extensive review of the medical literature regarding the management of insomnia and the elderly found considerable evidence of the effectiveness and durability of nondrug treatments for insomnia in adults of all ages and that these interventions are underused. Compared with the benzodiazepines
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In addition, the effectiveness and safety of long-term use of these agents remain to be determined. More research is needed to evaluate the long-term effects of treatment and the most appropriate management strategy for elderly persons with chronic insomnia.
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can be a common side effect, with potentially severe consequences). Triazolam causes anterograde amnesia, which is why so many dentists administer it to patients undergoing even minor dental procedures. This practice is known as sedation dentistry.
7514: 839:. It is an ideal benzodiazepine for this use because of its fast onset of action and short half-life. It puts a person to sleep for about 1.5 hours, allowing its user to avoid morning drowsiness. Triazolam is also sometimes used as an 1223:
Triazolam, like other benzodiazepines, is susceptible to misuse and abuse. Its rapid onset of action and short half life contribute to its abuse potential, but its relative obscurity compared to other fast-acting benzodiazepines (such as
1232:) prevent its abuse from becoming particularly commonplace. Likewise, because it is not prescribed as often or as readily as alprazolam or lorazepam, there is less triazolam available to be diverted for recreational use. 818:
Triazolam was initially patented in 1970 and went on sale in the United States in 1982. In 2017, it was the 289th most commonly prescribed medication in the United States, with more than one million prescriptions.
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Other withdrawal symptoms can range from mild unpleasant feelings to a major withdrawal syndrome, including stomach cramps, vomiting, muscle cramps, sweating, tremor, and in rare cases, convulsions.
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be updated for all benzodiazepine medicines to describe the risks of abuse, misuse, addiction, physical dependence, and withdrawal reactions consistently across all the medicines in the class.
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Tokinaga N, Kondo T, Kaneko S, Otani K, Mihara K, Morita S (December 1996). "Hallucinations after a therapeutic dose of benzodiazepine hypnotics with co-administration of erythromycin".
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Kudo K, Imamura T, Jitsufuchi N, Zhang XX, Tokunaga H, Nagata T (April 1997). "Death attributed to the toxic interaction of triazolam, amitriptyline and other psychotropic drugs".
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Co-administration of benzodiazepine drugs at therapeutic doses with erythromycin may cause serious psychotic symptoms, especially in those with other physical complications.
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or to reduce anxiety during brief events, such as MRI scans and nonsurgical dental procedures. Triazolam is ineffective in maintaining sleep due to its short half-life, with
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Mattila ME, Mattila MJ, Nuotto E (April 1992). "Caffeine moderately antagonizes the effects of triazolam and zopiclone on the psychomotor performance of healthy subjects".
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Varhe A, Olkkola KT, Neuvonen PJ (December 1994). "Oral triazolam is potentially hazardous to patients receiving systemic antimycotics ketoconazole or itraconazole".
2152: 1366: 6491: 6481: 1361:[Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). 5024: 1841:
Authier N, Balayssac D, Sautereau M, Zangarelli A, Courty P, Somogyi AA, et al. (November 2009). "Benzodiazepine dependence: focus on withdrawal syndrome".
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Chweh AY, Swinyard EA, Wolf HH, Kupferberg HJ (February 1985). "Effect of GABA agonists on the neurotoxicity and anticonvulsant activity of benzodiazepines".
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Griffiths RR, Johnson MW (2005). "Relative abuse liability of hypnotic drugs: a conceptual framework and algorithm for differentiating among compounds".
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of triazolam, leading to greatly enhanced effects. Anxiety, tremor, and depression have been documented in a case report following administration of
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demonstrated that residual "hangover" effects after nighttime administration of triazolam such as sleepiness, psychomotor impairment, and diminished
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Bayer AJ, Bayer EM, Pathy MS, Stoker MJ (1986). "A double-blind controlled study of chlormethiazole and triazolam as hypnotics in the elderly".
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Kales A, Scharf MB, Kales JD, Soldatos CR (April 1979). "Rebound insomnia. A potential hazard following withdrawal of certain benzodiazepines".
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Mauri MC, Gianetti S, Pugnetti L, Altamura AC (1993). "Quazepam versus triazolam in patients with sleep disorders: a double-blind study".
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the side effects and potency of this medication are understood by the user prior to using it in a relatively more public environment (as
787:(BZD) derivatives. It possesses pharmacological properties similar to those of other benzodiazepines, but it is generally only used as a 7738: 7424: 7419: 6969: 6703: 6698: 6693: 6683: 6534: 4009: 6894: 6354: 2466: 242: 695: 925:
Triazolam, although a short-acting benzodiazepine, may cause residual impairment into the next day, especially the next morning. A
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Mets MA, Volkerts ER, Olivier B, Verster JC (August 2010). "Effect of hypnotic drugs on body balance and standing steadiness".
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functions may persist into the next day, which may impair the ability of users to drive safely and increase risks of falls and
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Death can occur from triazolam overdose, but is more likely to occur in combination with other depressant drugs such as
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receptor. The half-life of triazolam is only 2 hours making it a very short acting benzodiazepine drug. It has
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InChI=1S/C17H12Cl2N4/c1-10-21-22-16-9-20-17(12-4-2-3-5-14(12)19)13-8-11(18)6-7-15(13)23(10)16/h2-8H,9H2,1H3
621: 502: 7808: 7482: 6593: 5046: 4696: 1326:"FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links.)" 1218: 582: 7778: 6603: 4801: 4615: 1012:. Triazolam belongs to the Pregnancy Category X of the FDA. It is known to have the potential to cause 1001:
Benzodiazepines require special precautions if used in the elderly, during pregnancy, in children, in
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Its use at low doses has been deemed acceptable by the US FDA and in several other countries.
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Vermeeren A (2004). "Residual effects of hypnotics: epidemiology and clinical implications".
1520: 1009: 551: 442: 1182: 7487: 6113: 5988: 4981: 4499: 3337: 3177: 2728: 511: 406: 343: 6577: 1185:. It does not generate active metabolites. Triazolam is a short-acting benzodiazepine, is 491: 8: 7613: 7496: 6623: 6549: 5638: 5480: 5188: 4467: 4462: 4029: 3586: 3285: 2494: 397: 164: 625: 602: 7590: 7253: 7151: 6808: 6441: 5813: 5415: 4898: 4328: 4244: 3609: 2601: 2183: 2129: 2098: 2086: 2055: 1977: 1965: 1686: 1025: 131: 2274: 1784: 7733: 7504: 7447: 7388: 7156: 6728: 5823: 5600: 5595: 5143: 4291: 4249: 4082: 3757: 3752: 3290: 2611: 2394: 2367: 2363: 2305: 2278: 2217: 2175: 2133: 2090: 2047: 2012: 1969: 1929: 1858: 1823: 1788: 1713: 1678: 1674: 1582: 1528: 1501: 1279:. Other names include 2'-chloroxanax, chloroxanax, triclazolam, and chlorotriazolam. 895: 93: 2208:
Arayne MS, Sultana N, Bibi Z (October 2005). "Grape fruit juice-drug interactions".
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reduces the effectiveness of triazolam. Other important interactions include
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The pharmacological effects of triazolam are similar to those of most other
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Bain KT (June 2006). "Management of chronic insomnia in elderly persons".
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The drug is marketed in English-speaking countries under the brand names
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This article incorporates text from this source, which is in the
942: 836: 800: 894:, tiredness, confusional states/memory impairment, cramps/pain, 7623: 7586: 7208: 7161: 7032: 7014: 6974: 6658: 6456: 5102: 4254: 4150: 1162: 562: 361: 1704:
Lieberherr S, Scollo-Lavizzari G, Battegay R (June 1991). "".
1005:, or in other drug-dependent individuals and individuals with 6984: 5127: 4447: 2413:"List of psychotropic substances under international control" 1572: 901:
Rare (<0.5% of patients): constipation, taste alteration,
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Triazolam is usually used for short-term treatment of acute
587: 37: 6417: 3594: 2349: 1193: 522: 2260: 1911: 3321: 1333: 2322: 2072: 1805: 959: 2422:. International Narcotics Control Board. Archived from 1575:
International Journal of Clinical Pharmacology Research
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A review of the literature found that long-term use of
5173: 1482:"Benzodiazepine metabolism: an analytical perspective" 1115:. Triazolam should not be administered to patients on 7776: 4967: 1951: 1294: 1292: 2115: 2029: 1630: 1628: 1626: 1480:Mandrioli R, Mercolini L, Raggi MA (October 2008). 1318: 450: 1773:Journal of the American Pharmaceutical Association 1289: 7726:Unsorted benzodiazepine site positive modulators: 2207: 1997:The American Journal of Geriatric Pharmacotherapy 1623: 19:"Halcion" redirects here. For similar terms, see 7800: 2384: 1024:Triazolam, similar to other benzodiazepines and 430: 405: 3556: 1771:Kirkwood CK (1999). "Management of insomnia". 1448: 871:associated with the use of triazolam include: 7819:GABAA receptor positive allosteric modulators 5159: 4571:Serotonin antagonists and reuptake inhibitors 3542: 2460: 883:, feeling of lightness, coordination problems 2236:"Medicines You Should Not Take with Atripla" 1954:Acta Psychiatrica Scandinavica. Supplementum 119: 5175: 4960: 2298:Schweizerische Rundschau für Medizin Praxis 2295: 2210:Pakistan Journal of Pharmaceutical Sciences 1706:Schweizerische Rundschau für Medizin Praxis 295:In general: ℞ (Prescription only) 5166: 5152: 3549: 3535: 2467: 2453: 2150: 1444: 1442: 1440: 1438: 1436: 1300:"Triazolam (Halcion) Use During Pregnancy" 974:, including triazolam, is associated with 624: 601: 490: 1905: 1660: 886:Less common (0.9% to 0.5% of patients): 875:Relatively common (>1% of patients): 510: 1947: 1945: 1943: 1770: 2323:Professor heather Ashton (April 2007). 1518: 1433: 909:/allergy, dreams/nightmares, insomnia, 717:Cc1nnc2n1-c1ccc(Cl)cc1C(c1ccccc1Cl)=NC2 597: 470: 92: 16:Triazolobenzodiazepine class medication 7801: 2032:Clinical Pharmacology and Therapeutics 1353: 1207: 615: 384:8-Chloro-6-(2-chlorophenyl)-1-methyl-4 287: 260: 5147: 3530: 2448: 2405: 2075:Psychiatry and Clinical Neurosciences 1940: 1525:A Historical Dictionary of Psychiatry 1417:. non-benzodiazepines. Archived from 1249:Convention on Psychotropic Substances 960:Tolerance, dependence, and withdrawal 570: 550: 272: 110: 78: 7767:GABA metabolism/transport modulators 1994: 996: 184: 7384:Trichloroethane (methyl chloroform) 2474: 1549:"Triazolam - Drug Usage Statistics" 1212: 815:properties are pronounced as well. 530: 421: 13: 6447:11-Methoxy-12-hydroxydehydrokavain 2387:The Journal of Clinical Psychiatry 2325:"Benzodiazepine equivalency table" 2130:10.1111/j.1600-0773.1992.tb00473.x 2087:10.1111/j.1440-1819.1996.tb00577.x 1966:10.1111/j.1600-0447.1986.tb10544.x 1843:Annales Pharmaceutiques Françaises 1369:from the original on 3 August 2023 966:Benzodiazepine withdrawal syndrome 316:44% (oral route), 53% (sublingual) 14: 7845: 7194:Acetylglycinamide chloral hydrate 4276:Acetylglycinamide chloral hydrate 3511:* atypical activity profile (not 3449:Tetrahydroisoquinobenzodiazepines 1133:Symptoms of an overdose include: 1117:efavirenz/emtricitabine/tenofovir 211: 142: 7786: 1752: 1675:10.2165/00023210-200418050-00003 1607:. September 2005. Archived from 843:in medical procedures requiring 833:circadian rhythm sleep disorders 661: 655: 649: 45: 36: 7614:Menthyl isovalerate (validolum) 3491:Alprazolam triazolobenzophenone 2378: 2343: 2316: 2296:Oelschläger H (July 1989). "". 2289: 2254: 2228: 2201: 2144: 2109: 2066: 2023: 2009:10.1016/j.amjopharm.2006.06.006 1988: 1869: 1834: 1799: 1764: 1724: 1697: 1654: 1593: 1566: 1235: 1176: 1039: 863: 822: 742:Key:JOFWLTCLBGQGBO-UHFFFAOYSA-N 248: 6563:Allopregnanolone (brexanolone) 2263:Forensic Science International 1541: 1512: 1473: 1407: 1381: 1347: 1258: 1051:have a profound effect on the 643: 237: 224: 1: 7759:Receptor/signaling modulators 6315:Ampelopsin (dihydromyricetin) 2275:10.1016/S0379-0738(97)02110-5 2118:Pharmacology & Toxicology 1785:10.1016/S1086-5802(15)30354-5 1389:"What Is Triazolam Used For?" 1282: 7509:ergoloid (dihydroergotoxine) 6594:anabolic-androgenic steroids 5376:Butabarbital/Secbutabarbital 5181:receptor positive modulators 2364:10.1016/0024-3205(85)90193-6 1855:10.1016/j.pharma.2009.07.001 1738:Food and Drug Administration 1061:Following administration of 950:Food and Drug Administration 767:, sold under the brand name 7: 6149:Triflunordazepam (Ro5-2904) 4802:Tetracyclic antidepressants 4616:Tetracyclic antidepressants 2160:Psychopharmacology Bulletin 2151:Wang JS, DeVane CL (2003). 1877:"Halcion triazolam tablets" 1636:"Halcion- triazolam tablet" 1527:. Oxford University Press. 1219:Benzodiazepine use disorder 1204:effects on brain function. 1122: 10: 7850: 6477:5,6,7,8-Tetrahydroyangonin 1926:10.1016/j.smrv.2009.10.008 1498:10.2174/138920008786049258 1365:(published 4 April 2023). 1216: 1126: 1019: 963: 948:In September 2020, the US 633:Chemical and physical data 252:: Prescription only ( 18: 7829:Drugs developed by Pfizer 7752: 7402: 7170: 7107: 7074: 7041: 7013: 6727: 6669:Pregnanolone (eltanolone) 6548: 6505: 6416: 6388: 6300: 6182: 5624: 5311: 5212:Chlorobutanol (cloretone) 5187: 5005: 4958: 4930: 4897: 4877: 4823: 4779:Tricyclic antidepressants 4764: 4752: 4695: 4637: 4593:Tricyclic antidepressants 4561: 4498: 4486: 4415: 4263: 4200: 4167: 4149: 4081: 4028: 3985: 3957: 3899: 3776: 3633: 3585: 3573: 3509: 3483: 3464: 3448: 3432: 3394: 3376: 3360: 3336: 3250: 3222: 3186: 3080: 2986: 2945: 2909: 2482: 1779:(5): 688–96, quiz 713–4. 1253:Controlled Substances Act 1171:tricyclic antidepressants 750: 725: 705: 683: 670: 637: 632: 613: 581: 561: 541: 521: 501: 481: 461: 441: 416: 396: 372: 367: 355: 342: 332: 320: 310: 302: 201: 196: 171: 156: 130: 100: 86: 68: 58: 53: 44: 35: 7834:2-Chlorophenyl compounds 7763:GABA receptor modulators 7673:sulfonmethane (sulfonal) 4364:Sulfonmethane (sulfonal) 3378:Pyridotriazolodiazepines 3252:Thienotriazolodiazepines 1820:10.1001/jama.241.16.1692 1143:(respiratory depression) 799:properties, triazolam's 783:(TBZD) class, which are 21:Halcyon (disambiguation) 7824:Triazolobenzodiazepines 4851:Atypical antipsychotics 4665:Atypical antipsychotics 3484:Benzodiazepine prodrugs 2988:Triazolobenzodiazepines 1486:Current Drug Metabolism 1363:Diário Oficial da União 1129:Benzodiazepine overdose 388:-triazolobenzodiazepine 7649:Retigabine (ezogabine) 6925:Lirequinil (Ro41-3696) 6492:7,8-Dihydromethysticin 6482:5,6-Dehydromethysticin 5361:Benzylbutylbarbiturate 5025:Chlorophenylalkyldiols 4833:Typical antipsychotics 4647:Typical antipsychotics 3466:Pyrrolobenzodiazepines 3187:Oxazolobenzodiazepines 3081:Imidazobenzodiazepines 3064:(active metabolite of 2566:Desmethylflunitrazepam 1960:(suppl 329): 104–111. 1914:Sleep Medicine Reviews 1415:"Benzodiazepine Names" 921:, weakness, congestion 869:Adverse drug reactions 781:triazolobenzodiazepine 773:central nervous system 3338:Thienobenzodiazepines 2044:10.1038/clpt.1994.184 1010:psychiatric disorders 898:, visual disturbances 851:showing superiority. 795:. In addition to the 7704:constituents (e.g., 7488:Deuterated etifoxine 6550:Neuroactive steroids 6520:Apronal (apronalide) 6372:constituents (e.g., 5989:N-Desalkylflurazepam 4982:Gabapentin enacarbil 4030:Neuroactive steroids 4000:Apronal (apronalide) 2946:2,3-Benzodiazepines* 2331:on 28 September 2007 945:have been reported. 779:tranquilizer of the 233:(Psychoactive drugs) 7497:dihydroergocryptine 6809:Pyrazolopyrimidines 6467:5,6-Dihydroyangonin 6452:7,8-Dihydroyangonin 5639:3-Hydroxyphenazepam 5481:Methylphenobarbital 3286:Deschloroclotizolam 2910:1,5-Benzodiazepines 2732:-Desalkylflurazepam 2495:3-Hydroxyphenazepam 2483:1,4-Benzodiazepines 2038:(6 Pt 1): 601–607. 1742:. 23 September 2020 1306:. 18 September 2020 1208:Society and culture 952:(FDA) required the 771:among others, is a 220:(Prescription only) 32: 7809:1982 introductions 7591:4-O-methylhonokiol 7254:Dichloralphenazone 7152:Methylmethaqualone 6729:Nonbenzodiazepines 6442:Desmethoxyyangonin 6437:11-Hydroxyyangonin 6432:11-Methoxyyangonin 6427:10-Methoxyyangonin 5814:Ethyl carfluzepate 5416:Cyclopentobarbital 5047:Diethylpropanediol 4329:Dichloralphenazone 4245:Methylmethaqualone 4083:Nonbenzodiazepines 3610:Diethylpropanediol 3395:Pyrazolodiazepines 2602:Ethyl carfluzepate 2393:(Suppl 9): 31–41. 2304:(27–28): 766–772. 2172:10.1007/BF01990373 1893:on 6 November 2003 1642:. 10 December 2019 1519:Shorter E (2005). 1421:on 8 December 2008 1026:nonbenzodiazepines 28: 7774: 7773: 7734:MRK-409 (MK-0343) 7505:dihydroergotamine 7448:potassium bromide 7442:compounds (e.g., 7389:Trichloroethylene 7157:Nitromethaqualone 7076:Pyrazolopyridines 6578:3α-Androstanediol 6472:7,8-Dihydrokavain 5824:Ethyl loflazepate 5601:Thiotetrabarbital 5217:Ethanol (alcohol) 5141: 5140: 4893: 4892: 4691: 4690: 4411: 4410: 4292:Potassium bromide 4250:Nitromethaqualone 3758:Thiotetrabarbital 3605:Ethanol (alcohol) 3524: 3523: 3433:Pyrrolodiazepines 3291:Deschloroetizolam 3260:α-Hydroxyetizolam 2612:Ethyl loflazepate 2429:on 31 August 2012 1814:(16): 1692–1695. 1611:on 1 January 2019 1395:. 1 November 2022 1357:(31 March 2023). 997:Contraindications 762: 761: 696:Interactive image 583:CompTox Dashboard 291: 276: 264: 256:for higher doses) 251: 240: 228: 215: 146: 113: 7841: 7791: 7790: 7789: 7782: 7493:Dihydroergolines 7410:3-Hydroxybutanal 7043:Piperidinediones 6776:Imidazopyridines 6310:6-Methylapigenin 6242:Hydroxyphenamate 6114:SH-053-R-CH3-2′F 5819:Ethyl dirazepate 5699:Chlordiazepoxide 5591:Thiobutabarbital 5303:Trifluoroethanol 5293:Trichloroethanol 5283:-Pentanol (2M2B) 5177: 5168: 5161: 5154: 5145: 5144: 5066:muscle relaxants 4969: 4966: 4762: 4761: 4496: 4495: 4433:4-Fluorophenibut 4169:Piperidinediones 4043:Allopregnanolone 3625:Trichloroethanol 3583: 3582: 3551: 3544: 3537: 3528: 3527: 3361:Pyridodiazepines 3224:Thienodiazepines 3178:SH-053-R-CH3-2′F 2891:Triflunordazepam 2607:Ethyl dirazepate 2521:Chlordiazepoxide 2469: 2462: 2455: 2446: 2445: 2439: 2438: 2436: 2434: 2428: 2417: 2409: 2403: 2402: 2382: 2376: 2375: 2347: 2341: 2340: 2338: 2336: 2327:. Archived from 2320: 2314: 2313: 2293: 2287: 2286: 2258: 2252: 2251: 2249: 2247: 2242:on 25 April 2010 2232: 2226: 2225: 2205: 2199: 2198: 2196: 2190:. Archived from 2157: 2148: 2142: 2141: 2113: 2107: 2106: 2070: 2064: 2063: 2027: 2021: 2020: 1992: 1986: 1985: 1949: 1938: 1937: 1909: 1903: 1902: 1900: 1898: 1892: 1886:. Archived from 1881: 1873: 1867: 1866: 1838: 1832: 1831: 1803: 1797: 1796: 1768: 1762: 1756: 1755: 1751: 1749: 1747: 1728: 1722: 1721: 1701: 1695: 1694: 1658: 1652: 1651: 1649: 1647: 1632: 1621: 1620: 1618: 1616: 1597: 1591: 1590: 1570: 1564: 1563: 1561: 1559: 1545: 1539: 1538: 1516: 1510: 1509: 1477: 1471: 1470: 1468: 1466: 1446: 1431: 1430: 1428: 1426: 1411: 1405: 1404: 1402: 1400: 1385: 1379: 1378: 1376: 1374: 1351: 1345: 1344: 1342: 1340: 1330:nctr-crs.fda.gov 1322: 1316: 1315: 1313: 1311: 1296: 1245:Schedule IV drug 1213:Recreational use 1191:neurotransmitter 1089:grapefruit juice 1070: 1053:pharmacokinetics 988:rebound insomnia 984:rebound insomnia 758: 757: 698: 678: 663: 657: 651: 645: 628: 617: 606: 605: 591: 589: 574: 554: 534: 514: 494: 474: 454: 434: 424: 423: 409: 347: 289: 286: 281: 274: 271: 262: 259: 250: 247: 239: 236: 226: 223: 213: 210: 188: 144: 141: 123: 112: 109: 96: 82: 49: 40: 33: 31: 27: 7849: 7848: 7844: 7843: 7842: 7840: 7839: 7838: 7799: 7798: 7797: 7787: 7785: 7777: 7775: 7770: 7748: 7706:isovaleric acid 7669:Sulfonylalkanes 7567:Hopantenic acid 7551:tolfenamic acid 7539:flufenamic acid 7501:dihydroergosine 7444:lithium bromide 7403:Others/unsorted 7398: 7259:Dichloromethane 7234:Chloral hydrate 7229:Chloral betaine 7166: 7103: 7070: 7037: 7009: 6738:Cyclopyrrolones 6723: 6629:Etiocholanolone 6544: 6501: 6462:5-Hydroxykavain 6412: 6384: 6296: 6178: 5626:Benzodiazepines 5620: 5431:Ethallobarbital 5426:Enallylpropymal 5307: 5288:Tribromoethanol 5275:-Butanol (2M2P) 5221:alcoholic drink 5183: 5180: 5172: 5142: 5137: 5001: 4964: 4954: 4926: 4889: 4873: 4819: 4766:Antidepressants 4757: 4748: 4719:Dexmedetomidine 4700: 4687: 4633: 4563:Antidepressants 4557: 4518:Diphenhydramine 4491: 4482: 4420: 4407: 4396:Isovaleric acid 4359:Sulfonylalkanes 4314:Chloral hydrate 4309:Chloral betaine 4287:Lithium bromide 4259: 4196: 4163: 4145: 4077: 4024: 3981: 3953: 3895: 3778:Benzodiazepines 3772: 3678:Ethallobarbital 3629: 3578: 3569: 3555: 3525: 3520: 3516: 3505: 3479: 3460: 3444: 3428: 3390: 3372: 3356: 3332: 3246: 3218: 3182: 3076: 2982: 2941: 2905: 2478: 2476:Benzodiazepines 2473: 2443: 2442: 2432: 2430: 2426: 2415: 2411: 2410: 2406: 2383: 2379: 2348: 2344: 2334: 2332: 2321: 2317: 2294: 2290: 2259: 2255: 2245: 2243: 2234: 2233: 2229: 2206: 2202: 2197:on 9 July 2007. 2194: 2155: 2149: 2145: 2114: 2110: 2071: 2067: 2028: 2024: 1993: 1989: 1950: 1941: 1910: 1906: 1896: 1894: 1890: 1879: 1875: 1874: 1870: 1839: 1835: 1804: 1800: 1769: 1765: 1753: 1745: 1743: 1730: 1729: 1725: 1712:(24): 673–675. 1702: 1698: 1659: 1655: 1645: 1643: 1634: 1633: 1624: 1614: 1612: 1605:Dentistry Today 1599: 1598: 1594: 1571: 1567: 1557: 1555: 1547: 1546: 1542: 1535: 1517: 1513: 1478: 1474: 1464: 1462: 1447: 1434: 1424: 1422: 1413: 1412: 1408: 1398: 1396: 1393:www.icliniq.com 1387: 1386: 1382: 1372: 1370: 1352: 1348: 1338: 1336: 1324: 1323: 1319: 1309: 1307: 1298: 1297: 1290: 1285: 1261: 1243:Triazolam is a 1238: 1221: 1215: 1210: 1199: 1183:benzodiazepines 1179: 1141:Hypoventilation 1131: 1125: 1060: 1059:and triazolam. 1042: 1022: 999: 980:drug dependence 972:benzodiazepines 968: 962: 866: 825: 813:muscle relaxant 793:severe insomnia 753: 751: 746: 743: 738: 733: 732: 721: 718: 713: 712: 701: 676: 666: 660: 654: 648: 609: 585: 577: 557: 537: 517: 497: 477: 457: 437: 420: 412: 392: 389: 380: 379: 345: 334:Onset of action 312:Bioavailability 304:Pharmacokinetic 298: 279: 192: 159: 152: 133: 126: 24: 17: 12: 11: 5: 7847: 7837: 7836: 7831: 7826: 7821: 7816: 7811: 7796: 7795: 7772: 7771: 7753: 7750: 7749: 7747: 7746: 7741: 7736: 7731: 7722: 7721: 7714:valerenic acid 7699: 7694: 7684: 7666: 7661: 7656: 7651: 7646: 7641: 7636: 7631: 7626: 7621: 7616: 7611: 7606: 7584: 7579: 7574: 7569: 7564: 7559: 7554: 7543:mefenamic acid 7532: 7527: 7522: 7517: 7512: 7490: 7485: 7480: 7475: 7470: 7465: 7460: 7455: 7452:sodium bromide 7437: 7427: 7422: 7417: 7412: 7406: 7404: 7400: 7399: 7397: 7396: 7391: 7386: 7381: 7376: 7371: 7366: 7361: 7356: 7351: 7346: 7341: 7336: 7331: 7326: 7321: 7319:Methoxypropane 7316: 7314:Methoxyflurane 7311: 7306: 7301: 7296: 7291: 7286: 7281: 7276: 7274:Ethyl chloride 7271: 7266: 7261: 7256: 7251: 7246: 7241: 7236: 7231: 7226: 7221: 7216: 7211: 7206: 7201: 7196: 7191: 7186: 7180: 7178: 7168: 7167: 7165: 7164: 7159: 7154: 7149: 7144: 7139: 7134: 7129: 7124: 7119: 7113: 7111: 7109:Quinazolinones 7105: 7104: 7102: 7101: 7096: 7091: 7086: 7080: 7078: 7072: 7071: 7069: 7068: 7063: 7058: 7053: 7047: 7045: 7039: 7038: 7036: 7035: 7030: 7025: 7019: 7017: 7011: 7010: 7008: 7007: 7002: 6997: 6992: 6987: 6982: 6977: 6972: 6967: 6962: 6957: 6952: 6947: 6942: 6937: 6932: 6927: 6922: 6917: 6912: 6907: 6902: 6897: 6892: 6887: 6882: 6877: 6872: 6867: 6862: 6852: 6851: 6846: 6841: 6836: 6831: 6826: 6821: 6816: 6804: 6803: 6798: 6793: 6788: 6783: 6771: 6770: 6765: 6760: 6755: 6750: 6745: 6733: 6731: 6725: 6724: 6722: 6721: 6716: 6711: 6706: 6701: 6696: 6691: 6686: 6681: 6676: 6671: 6666: 6661: 6656: 6651: 6646: 6641: 6636: 6631: 6626: 6621: 6616: 6611: 6606: 6601: 6596: 6590: 6585: 6580: 6575: 6570: 6565: 6560: 6554: 6552: 6546: 6545: 6543: 6542: 6537: 6532: 6527: 6522: 6517: 6511: 6509: 6503: 6502: 6500: 6499: 6494: 6489: 6484: 6479: 6474: 6469: 6464: 6459: 6454: 6449: 6444: 6439: 6434: 6429: 6423: 6421: 6414: 6413: 6411: 6410: 6405: 6400: 6394: 6392: 6386: 6385: 6383: 6382: 6377: 6367: 6362: 6357: 6352: 6347: 6342: 6337: 6332: 6327: 6322: 6317: 6312: 6306: 6304: 6298: 6297: 6295: 6294: 6289: 6284: 6279: 6274: 6269: 6264: 6259: 6254: 6249: 6244: 6239: 6234: 6229: 6224: 6219: 6214: 6209: 6204: 6199: 6194: 6188: 6186: 6180: 6179: 6177: 6176: 6171: 6166: 6161: 6156: 6151: 6146: 6141: 6136: 6131: 6126: 6121: 6116: 6111: 6106: 6101: 6096: 6091: 6086: 6081: 6076: 6071: 6066: 6061: 6056: 6051: 6046: 6041: 6036: 6031: 6026: 6021: 6016: 6011: 6006: 6001: 5996: 5991: 5986: 5981: 5976: 5971: 5966: 5961: 5956: 5951: 5946: 5941: 5936: 5931: 5926: 5921: 5916: 5911: 5906: 5901: 5896: 5891: 5886: 5881: 5876: 5871: 5866: 5861: 5856: 5851: 5846: 5841: 5836: 5831: 5826: 5821: 5816: 5811: 5806: 5801: 5796: 5791: 5786: 5781: 5776: 5771: 5766: 5761: 5756: 5751: 5746: 5741: 5736: 5731: 5726: 5721: 5716: 5711: 5706: 5701: 5696: 5691: 5686: 5681: 5676: 5671: 5666: 5661: 5656: 5651: 5646: 5641: 5636: 5630: 5628: 5622: 5621: 5619: 5618: 5613: 5608: 5603: 5598: 5593: 5588: 5583: 5578: 5573: 5568: 5563: 5558: 5553: 5548: 5543: 5538: 5533: 5531:Propylbarbital 5528: 5523: 5518: 5513: 5508: 5503: 5498: 5493: 5488: 5483: 5478: 5473: 5468: 5463: 5458: 5453: 5448: 5443: 5438: 5433: 5428: 5423: 5418: 5413: 5408: 5406:Crotylbarbital 5403: 5398: 5393: 5388: 5383: 5378: 5373: 5371:Brophebarbital 5368: 5366:Brallobarbital 5363: 5358: 5353: 5348: 5343: 5338: 5333: 5328: 5323: 5317: 5315: 5309: 5308: 5306: 5305: 5300: 5295: 5290: 5285: 5277: 5269: 5264: 5259: 5254: 5252:Methylpentynol 5249: 5244: 5239: 5234: 5229: 5224: 5214: 5209: 5204: 5199: 5193: 5191: 5185: 5184: 5178: 5171: 5170: 5163: 5156: 5148: 5139: 5138: 5136: 5135: 5130: 5125: 5120: 5115: 5113:Passion flower 5110: 5100: 5095: 5094: 5093: 5088: 5083: 5078: 5073: 5059: 5054: 5049: 5044: 5043: 5042: 5037: 5032: 5022: 5021: 5020: 5009: 5007: 5003: 5002: 5000: 4999: 4994: 4989: 4984: 4979: 4973: 4971: 4962: 4956: 4955: 4953: 4952: 4947: 4942: 4936: 4934: 4928: 4927: 4925: 4924: 4919: 4914: 4909: 4903: 4901: 4895: 4894: 4891: 4890: 4888: 4887: 4881: 4879: 4875: 4874: 4872: 4871: 4870: 4869: 4863: 4858: 4848: 4847: 4846: 4840: 4838:Chlorpromazine 4829: 4827: 4825:Antipsychotics 4821: 4820: 4818: 4817: 4816: 4815: 4809: 4799: 4798: 4797: 4791: 4786: 4776: 4770: 4768: 4759: 4755: 4750: 4749: 4747: 4746: 4741: 4736: 4731: 4726: 4721: 4716: 4711: 4705: 4703: 4698: 4693: 4692: 4689: 4688: 4686: 4685: 4684: 4683: 4677: 4672: 4662: 4661: 4660: 4654: 4652:Chlorpromazine 4643: 4641: 4639:Antipsychotics 4635: 4634: 4632: 4631: 4630: 4629: 4623: 4613: 4612: 4611: 4605: 4600: 4590: 4589: 4588: 4583: 4578: 4567: 4565: 4559: 4558: 4556: 4555: 4550: 4545: 4540: 4535: 4530: 4525: 4520: 4515: 4513:Cyproheptadine 4510: 4504: 4502: 4500:Antihistamines 4493: 4489: 4484: 4483: 4481: 4480: 4475: 4470: 4465: 4460: 4457:sodium oxybate 4450: 4445: 4440: 4435: 4430: 4428:1,4-Butanediol 4424: 4422: 4418: 4413: 4412: 4409: 4408: 4406: 4405: 4404: 4403: 4401:Valerenic acid 4398: 4393: 4383: 4378: 4377: 4376: 4371: 4366: 4356: 4351: 4346: 4341: 4336: 4331: 4326: 4321: 4316: 4311: 4306: 4301: 4300: 4299: 4297:Sodium bromide 4294: 4289: 4278: 4273: 4267: 4265: 4261: 4260: 4258: 4257: 4252: 4247: 4242: 4237: 4232: 4227: 4222: 4217: 4212: 4206: 4204: 4202:Quinazolinones 4198: 4197: 4195: 4194: 4189: 4184: 4179: 4173: 4171: 4165: 4164: 4162: 4161: 4155: 4153: 4147: 4146: 4144: 4143: 4138: 4133: 4128: 4123: 4118: 4113: 4108: 4103: 4098: 4093: 4087: 4085: 4079: 4078: 4076: 4075: 4070: 4065: 4060: 4055: 4050: 4045: 4040: 4034: 4032: 4026: 4025: 4023: 4022: 4017: 4012: 4007: 4002: 3997: 3991: 3989: 3983: 3982: 3980: 3979: 3974: 3969: 3963: 3961: 3955: 3954: 3952: 3951: 3946: 3941: 3936: 3931: 3926: 3921: 3916: 3911: 3905: 3903: 3897: 3896: 3894: 3893: 3888: 3883: 3878: 3873: 3868: 3863: 3858: 3853: 3848: 3843: 3838: 3833: 3828: 3823: 3818: 3813: 3808: 3803: 3798: 3793: 3788: 3782: 3780: 3774: 3773: 3771: 3770: 3765: 3760: 3755: 3750: 3745: 3740: 3735: 3730: 3725: 3723:Propylbarbital 3720: 3715: 3710: 3705: 3700: 3695: 3690: 3685: 3680: 3675: 3670: 3665: 3660: 3655: 3650: 3645: 3639: 3637: 3631: 3630: 3628: 3627: 3622: 3620:Methylpentynol 3617: 3612: 3607: 3602: 3597: 3591: 3589: 3580: 3576: 3571: 3570: 3554: 3553: 3546: 3539: 3531: 3522: 3521: 3514: 3510: 3507: 3506: 3504: 3503: 3498: 3493: 3487: 3485: 3481: 3480: 3478: 3477: 3471: 3469: 3462: 3461: 3459: 3458: 3452: 3450: 3446: 3445: 3443: 3442: 3436: 3434: 3430: 3429: 3427: 3426: 3420: 3415: 3410: 3405: 3398: 3396: 3392: 3391: 3389: 3388: 3382: 3380: 3374: 3373: 3371: 3370: 3364: 3362: 3358: 3357: 3355: 3354: 3349: 3343: 3341: 3334: 3333: 3331: 3330: 3325: 3319: 3313: 3308: 3303: 3298: 3293: 3288: 3283: 3278: 3273: 3268: 3262: 3256: 3254: 3248: 3247: 3245: 3244: 3239: 3234: 3228: 3226: 3220: 3219: 3217: 3216: 3211: 3206: 3201: 3196: 3190: 3188: 3184: 3183: 3181: 3180: 3175: 3170: 3165: 3160: 3155: 3150: 3145: 3140: 3135: 3130: 3125: 3120: 3115: 3110: 3105: 3100: 3095: 3090: 3084: 3082: 3078: 3077: 3075: 3074: 3069: 3059: 3054: 3049: 3044: 3039: 3034: 3029: 3024: 3019: 3014: 3009: 3003: 2998: 2992: 2990: 2984: 2983: 2981: 2980: 2975: 2970: 2965: 2960: 2955: 2949: 2947: 2943: 2942: 2940: 2939: 2934: 2929: 2924: 2919: 2913: 2911: 2907: 2906: 2904: 2903: 2898: 2893: 2888: 2883: 2877: 2871: 2866: 2861: 2856: 2851: 2846: 2841: 2836: 2831: 2825: 2820: 2814: 2809: 2804: 2799: 2794: 2789: 2784: 2779: 2774: 2769: 2764: 2759: 2754: 2749: 2744: 2739: 2734: 2726: 2721: 2716: 2711: 2706: 2701: 2695: 2690: 2685: 2680: 2675: 2669: 2664: 2659: 2654: 2649: 2644: 2639: 2634: 2629: 2624: 2619: 2614: 2609: 2604: 2599: 2594: 2589: 2584: 2579: 2574: 2568: 2563: 2558: 2553: 2548: 2543: 2538: 2533: 2528: 2523: 2518: 2513: 2508: 2502: 2497: 2492: 2486: 2484: 2480: 2479: 2472: 2471: 2464: 2457: 2449: 2441: 2440: 2404: 2377: 2358:(8): 737–744. 2342: 2315: 2288: 2269:(1–2): 35–41. 2253: 2227: 2200: 2143: 2124:(4): 286–289. 2108: 2081:(6): 337–339. 2065: 2022: 2003:(2): 168–192. 1987: 1939: 1920:(4): 259–267. 1904: 1868: 1849:(6): 408–413. 1833: 1798: 1763: 1723: 1696: 1669:(5): 297–328. 1653: 1622: 1592: 1581:(3): 173–177. 1565: 1540: 1533: 1511: 1492:(8): 827–844. 1472: 1450:Wishart, David 1432: 1406: 1380: 1346: 1317: 1287: 1286: 1284: 1281: 1260: 1257: 1237: 1234: 1214: 1211: 1209: 1206: 1202:anticonvulsant 1197: 1178: 1175: 1159: 1158: 1153: 1152:Slurred speech 1150: 1144: 1138: 1124: 1121: 1113:troleandomycin 1067:kidney failure 1041: 1038: 1021: 1018: 998: 995: 976:drug tolerance 964:Main article: 961: 958: 923: 922: 899: 884: 865: 862: 824: 821: 809:anticonvulsant 785:benzodiazepine 760: 759: 748: 747: 745: 744: 741: 739: 736: 728: 727: 726: 723: 722: 720: 719: 716: 708: 707: 706: 703: 702: 700: 699: 691: 689: 681: 680: 674: 668: 667: 664: 658: 652: 646: 641: 635: 634: 630: 629: 619: 611: 610: 608: 607: 594: 592: 579: 578: 576: 575: 567: 565: 559: 558: 556: 555: 547: 545: 539: 538: 536: 535: 527: 525: 519: 518: 516: 515: 507: 505: 499: 498: 496: 495: 487: 485: 479: 478: 476: 475: 467: 465: 459: 458: 456: 455: 447: 445: 439: 438: 436: 435: 427: 425: 414: 413: 411: 410: 402: 400: 394: 393: 391: 390: 383: 375: 374: 373: 370: 369: 365: 364: 359: 353: 352: 349: 340: 339: 336: 330: 329: 324: 318: 317: 314: 308: 307: 300: 299: 297: 296: 293: 284: 269: 257: 245: 234: 221: 207: 205: 199: 198: 194: 193: 191: 190: 177: 175: 169: 168: 162: 160:administration 154: 153: 151: 150: 148: 138: 136: 128: 127: 125: 124: 106: 104: 98: 97: 90: 84: 83: 76: 66: 65: 62: 56: 55: 51: 50: 42: 41: 15: 9: 6: 4: 3: 2: 7846: 7835: 7832: 7830: 7827: 7825: 7822: 7820: 7817: 7815: 7812: 7810: 7807: 7806: 7804: 7794: 7784: 7783: 7780: 7769: 7768: 7764: 7760: 7757: 7751: 7745: 7742: 7740: 7737: 7735: 7732: 7730: 7727: 7724: 7723: 7719: 7715: 7711: 7710:isovaleramide 7707: 7703: 7700: 7698: 7695: 7692: 7688: 7685: 7682: 7678: 7674: 7670: 7667: 7665: 7662: 7660: 7657: 7655: 7652: 7650: 7647: 7645: 7642: 7640: 7637: 7635: 7632: 7630: 7627: 7625: 7622: 7620: 7617: 7615: 7612: 7610: 7607: 7604: 7600: 7596: 7592: 7588: 7585: 7583: 7580: 7578: 7575: 7573: 7570: 7568: 7565: 7563: 7560: 7558: 7555: 7552: 7548: 7547:niflumic acid 7544: 7540: 7536: 7533: 7531: 7528: 7526: 7523: 7521: 7518: 7516: 7513: 7510: 7506: 7502: 7498: 7494: 7491: 7489: 7486: 7484: 7481: 7479: 7476: 7474: 7473:Clomethiazole 7471: 7469: 7468:Chlormezanone 7466: 7464: 7461: 7459: 7458:Carbamazepine 7456: 7453: 7449: 7445: 7441: 7438: 7435: 7431: 7428: 7426: 7423: 7421: 7418: 7416: 7413: 7411: 7408: 7407: 7405: 7401: 7395: 7392: 7390: 7387: 7385: 7382: 7380: 7377: 7375: 7372: 7370: 7367: 7365: 7362: 7360: 7357: 7355: 7352: 7350: 7347: 7345: 7342: 7340: 7337: 7335: 7334:Nitrous oxide 7332: 7330: 7327: 7325: 7322: 7320: 7317: 7315: 7312: 7310: 7307: 7305: 7302: 7300: 7297: 7295: 7292: 7290: 7287: 7285: 7282: 7280: 7277: 7275: 7272: 7270: 7267: 7265: 7264:Diethyl ether 7262: 7260: 7257: 7255: 7252: 7250: 7247: 7245: 7242: 7240: 7237: 7235: 7232: 7230: 7227: 7225: 7222: 7220: 7217: 7215: 7212: 7210: 7207: 7205: 7202: 7200: 7197: 7195: 7192: 7190: 7187: 7185: 7182: 7181: 7179: 7177: 7173: 7169: 7163: 7160: 7158: 7155: 7153: 7150: 7148: 7145: 7143: 7140: 7138: 7135: 7133: 7130: 7128: 7125: 7123: 7120: 7118: 7115: 7114: 7112: 7110: 7106: 7100: 7097: 7095: 7092: 7090: 7087: 7085: 7082: 7081: 7079: 7077: 7073: 7067: 7066:Pyrithyldione 7064: 7062: 7059: 7057: 7054: 7052: 7049: 7048: 7046: 7044: 7040: 7034: 7031: 7029: 7026: 7024: 7021: 7020: 7018: 7016: 7012: 7006: 7003: 7001: 6998: 6996: 6993: 6991: 6988: 6986: 6983: 6981: 6978: 6976: 6973: 6971: 6968: 6966: 6963: 6961: 6958: 6956: 6953: 6951: 6948: 6946: 6943: 6941: 6938: 6936: 6933: 6931: 6928: 6926: 6923: 6921: 6918: 6916: 6913: 6911: 6908: 6906: 6903: 6901: 6898: 6896: 6893: 6891: 6888: 6886: 6883: 6881: 6878: 6876: 6873: 6871: 6868: 6866: 6863: 6861: 6857: 6854: 6853: 6850: 6847: 6845: 6842: 6840: 6837: 6835: 6832: 6830: 6827: 6825: 6822: 6820: 6817: 6815: 6811: 6810: 6806: 6805: 6802: 6799: 6797: 6794: 6792: 6789: 6787: 6784: 6782: 6778: 6777: 6773: 6772: 6769: 6766: 6764: 6761: 6759: 6756: 6754: 6751: 6749: 6746: 6744: 6740: 6739: 6735: 6734: 6732: 6730: 6726: 6720: 6717: 6715: 6712: 6710: 6707: 6705: 6702: 6700: 6697: 6695: 6692: 6690: 6687: 6685: 6682: 6680: 6677: 6675: 6672: 6670: 6667: 6665: 6662: 6660: 6657: 6655: 6652: 6650: 6647: 6645: 6642: 6640: 6637: 6635: 6632: 6630: 6627: 6625: 6622: 6620: 6617: 6615: 6612: 6610: 6607: 6605: 6602: 6600: 6597: 6595: 6591: 6589: 6586: 6584: 6581: 6579: 6576: 6574: 6571: 6569: 6566: 6564: 6561: 6559: 6556: 6555: 6553: 6551: 6547: 6541: 6538: 6536: 6533: 6531: 6528: 6526: 6523: 6521: 6518: 6516: 6513: 6512: 6510: 6508: 6504: 6498: 6495: 6493: 6490: 6488: 6485: 6483: 6480: 6478: 6475: 6473: 6470: 6468: 6465: 6463: 6460: 6458: 6455: 6453: 6450: 6448: 6445: 6443: 6440: 6438: 6435: 6433: 6430: 6428: 6425: 6424: 6422: 6419: 6415: 6409: 6406: 6404: 6401: 6399: 6396: 6395: 6393: 6391: 6387: 6381: 6378: 6375: 6371: 6368: 6366: 6363: 6361: 6358: 6356: 6353: 6351: 6348: 6346: 6343: 6341: 6338: 6336: 6333: 6331: 6328: 6326: 6323: 6321: 6318: 6316: 6313: 6311: 6308: 6307: 6305: 6303: 6299: 6293: 6290: 6288: 6285: 6283: 6280: 6278: 6275: 6273: 6272:Phenprobamate 6270: 6268: 6265: 6263: 6260: 6258: 6255: 6253: 6250: 6248: 6245: 6243: 6240: 6238: 6237:Hexapropymate 6235: 6233: 6230: 6228: 6225: 6223: 6220: 6218: 6215: 6213: 6212:Difebarbamate 6210: 6208: 6205: 6203: 6200: 6198: 6195: 6193: 6190: 6189: 6187: 6185: 6181: 6175: 6172: 6170: 6167: 6165: 6162: 6160: 6157: 6155: 6152: 6150: 6147: 6145: 6142: 6140: 6137: 6135: 6132: 6130: 6127: 6125: 6122: 6120: 6117: 6115: 6112: 6110: 6107: 6105: 6102: 6100: 6097: 6095: 6092: 6090: 6087: 6085: 6082: 6080: 6077: 6075: 6072: 6070: 6067: 6065: 6062: 6060: 6057: 6055: 6052: 6050: 6047: 6045: 6042: 6040: 6037: 6035: 6032: 6030: 6027: 6025: 6024:Nortetrazepam 6022: 6020: 6017: 6015: 6012: 6010: 6007: 6005: 6002: 6000: 5997: 5995: 5992: 5990: 5987: 5985: 5982: 5980: 5977: 5975: 5972: 5970: 5967: 5965: 5962: 5960: 5957: 5955: 5952: 5950: 5947: 5945: 5942: 5940: 5937: 5935: 5932: 5930: 5927: 5925: 5922: 5920: 5917: 5915: 5912: 5910: 5907: 5905: 5902: 5900: 5897: 5895: 5892: 5890: 5887: 5885: 5884:Flutoprazepam 5882: 5880: 5877: 5875: 5872: 5870: 5867: 5865: 5864:Flunitrazolam 5862: 5860: 5859:Flunitrazepam 5857: 5855: 5852: 5850: 5849:Flubromazolam 5847: 5845: 5844:Flubromazepam 5842: 5840: 5837: 5835: 5832: 5830: 5827: 5825: 5822: 5820: 5817: 5815: 5812: 5810: 5807: 5805: 5802: 5800: 5797: 5795: 5792: 5790: 5787: 5785: 5782: 5780: 5777: 5775: 5772: 5770: 5767: 5765: 5762: 5760: 5757: 5755: 5752: 5750: 5747: 5745: 5744:Cloniprazepam 5742: 5740: 5737: 5735: 5732: 5730: 5727: 5725: 5722: 5720: 5717: 5715: 5712: 5710: 5707: 5705: 5702: 5700: 5697: 5695: 5692: 5690: 5687: 5685: 5682: 5680: 5677: 5675: 5672: 5670: 5667: 5665: 5662: 5660: 5657: 5655: 5652: 5650: 5647: 5645: 5642: 5640: 5637: 5635: 5634:2-Oxoquazepam 5632: 5631: 5629: 5627: 5623: 5617: 5614: 5612: 5609: 5607: 5604: 5602: 5599: 5597: 5594: 5592: 5589: 5587: 5584: 5582: 5579: 5577: 5576:Thialbarbital 5574: 5572: 5571:Tetrabarbital 5569: 5567: 5564: 5562: 5559: 5557: 5556:Spirobarbital 5554: 5552: 5549: 5547: 5544: 5542: 5539: 5537: 5536:Proxibarbital 5534: 5532: 5529: 5527: 5526:Propallylonal 5524: 5522: 5519: 5517: 5514: 5512: 5509: 5507: 5506:Phenobarbital 5504: 5502: 5499: 5497: 5496:Pentobarbital 5494: 5492: 5489: 5487: 5486:Narcobarbital 5484: 5482: 5479: 5477: 5474: 5472: 5469: 5467: 5464: 5462: 5459: 5457: 5454: 5452: 5451:Heptobarbital 5449: 5447: 5444: 5442: 5439: 5437: 5434: 5432: 5429: 5427: 5424: 5422: 5421:Difebarbamate 5419: 5417: 5414: 5412: 5411:Cyclobarbital 5409: 5407: 5404: 5402: 5399: 5397: 5394: 5392: 5389: 5387: 5384: 5382: 5379: 5377: 5374: 5372: 5369: 5367: 5364: 5362: 5359: 5357: 5356:Benzobarbital 5354: 5352: 5349: 5347: 5344: 5342: 5339: 5337: 5334: 5332: 5329: 5327: 5324: 5322: 5319: 5318: 5316: 5314: 5310: 5304: 5301: 5299: 5296: 5294: 5291: 5289: 5286: 5284: 5282: 5278: 5276: 5274: 5270: 5268: 5265: 5263: 5260: 5258: 5255: 5253: 5250: 5248: 5245: 5243: 5240: 5238: 5235: 5233: 5230: 5228: 5227:Ethchlorvynol 5225: 5222: 5218: 5215: 5213: 5210: 5208: 5205: 5203: 5200: 5198: 5195: 5194: 5192: 5190: 5186: 5182: 5169: 5164: 5162: 5157: 5155: 5150: 5149: 5146: 5134: 5131: 5129: 5126: 5124: 5121: 5119: 5116: 5114: 5111: 5108: 5104: 5101: 5099: 5096: 5092: 5091:Methocarbamol 5089: 5087: 5084: 5082: 5081:Mephenoxalone 5079: 5077: 5074: 5072: 5071:Chlorphenesin 5069: 5068: 5067: 5063: 5060: 5058: 5055: 5053: 5050: 5048: 5045: 5041: 5040:Phenaglycodol 5038: 5036: 5033: 5031: 5028: 5027: 5026: 5023: 5019: 5016: 5015: 5014: 5011: 5010: 5008: 5004: 4998: 4995: 4993: 4990: 4988: 4985: 4983: 4980: 4978: 4975: 4974: 4972: 4970: 4957: 4951: 4948: 4946: 4943: 4941: 4938: 4937: 4935: 4933: 4929: 4923: 4920: 4918: 4915: 4913: 4910: 4908: 4905: 4904: 4902: 4900: 4896: 4886: 4883: 4882: 4880: 4876: 4867: 4864: 4862: 4859: 4857: 4854: 4853: 4852: 4849: 4844: 4841: 4839: 4836: 4835: 4834: 4831: 4830: 4828: 4826: 4822: 4813: 4810: 4808: 4805: 4804: 4803: 4800: 4795: 4792: 4790: 4787: 4785: 4784:Amitriptyline 4782: 4781: 4780: 4777: 4775: 4772: 4771: 4769: 4767: 4763: 4760: 4758: 4751: 4745: 4742: 4740: 4737: 4735: 4732: 4730: 4727: 4725: 4722: 4720: 4717: 4715: 4712: 4710: 4707: 4706: 4704: 4702: 4694: 4681: 4678: 4676: 4673: 4671: 4668: 4667: 4666: 4663: 4658: 4655: 4653: 4650: 4649: 4648: 4645: 4644: 4642: 4640: 4636: 4627: 4624: 4622: 4619: 4618: 4617: 4614: 4609: 4606: 4604: 4601: 4599: 4598:Amitriptyline 4596: 4595: 4594: 4591: 4587: 4584: 4582: 4579: 4577: 4574: 4573: 4572: 4569: 4568: 4566: 4564: 4560: 4554: 4551: 4549: 4546: 4544: 4541: 4539: 4536: 4534: 4533:Methapyrilene 4531: 4529: 4526: 4524: 4521: 4519: 4516: 4514: 4511: 4509: 4506: 4505: 4503: 4501: 4497: 4494: 4492: 4485: 4479: 4476: 4474: 4471: 4469: 4466: 4464: 4461: 4458: 4454: 4451: 4449: 4446: 4444: 4441: 4439: 4438:Aceburic acid 4436: 4434: 4431: 4429: 4426: 4425: 4423: 4421: 4414: 4402: 4399: 4397: 4394: 4392: 4391:Isovaleramide 4389: 4388: 4387: 4386:Sesquiterpene 4384: 4382: 4379: 4375: 4372: 4370: 4367: 4365: 4362: 4361: 4360: 4357: 4355: 4352: 4350: 4347: 4345: 4342: 4340: 4337: 4335: 4332: 4330: 4327: 4325: 4324:Clomethiazole 4322: 4320: 4317: 4315: 4312: 4310: 4307: 4305: 4302: 4298: 4295: 4293: 4290: 4288: 4285: 4284: 4282: 4279: 4277: 4274: 4272: 4269: 4268: 4266: 4262: 4256: 4253: 4251: 4248: 4246: 4243: 4241: 4238: 4236: 4233: 4231: 4228: 4226: 4223: 4221: 4218: 4216: 4213: 4211: 4208: 4207: 4205: 4203: 4199: 4193: 4190: 4188: 4187:Pyrithyldione 4185: 4183: 4180: 4178: 4175: 4174: 4172: 4170: 4166: 4160: 4157: 4156: 4154: 4152: 4148: 4142: 4139: 4137: 4134: 4132: 4129: 4127: 4124: 4122: 4119: 4117: 4114: 4112: 4109: 4107: 4104: 4102: 4099: 4097: 4094: 4092: 4089: 4088: 4086: 4084: 4080: 4074: 4071: 4069: 4066: 4064: 4061: 4059: 4056: 4054: 4051: 4049: 4046: 4044: 4041: 4039: 4036: 4035: 4033: 4031: 4027: 4021: 4018: 4016: 4013: 4011: 4008: 4006: 4003: 4001: 3998: 3996: 3993: 3992: 3990: 3988: 3984: 3978: 3975: 3973: 3970: 3968: 3965: 3964: 3962: 3960: 3956: 3950: 3947: 3945: 3942: 3940: 3939:Phenprobamate 3937: 3935: 3934:Methocarbamol 3932: 3930: 3927: 3925: 3924:Hexapropymate 3922: 3920: 3917: 3915: 3912: 3910: 3907: 3906: 3904: 3902: 3898: 3892: 3889: 3887: 3884: 3882: 3879: 3877: 3874: 3872: 3869: 3867: 3864: 3862: 3859: 3857: 3854: 3852: 3849: 3847: 3844: 3842: 3841:Flutoprazepam 3839: 3837: 3834: 3832: 3829: 3827: 3826:Flunitrazepam 3824: 3822: 3821:Flunitrazolam 3819: 3817: 3816:Flubromazolam 3814: 3812: 3809: 3807: 3804: 3802: 3799: 3797: 3794: 3792: 3789: 3787: 3784: 3783: 3781: 3779: 3775: 3769: 3766: 3764: 3761: 3759: 3756: 3754: 3751: 3749: 3746: 3744: 3741: 3739: 3736: 3734: 3731: 3729: 3726: 3724: 3721: 3719: 3718:Phenobarbital 3716: 3714: 3711: 3709: 3708:Pentobarbital 3706: 3704: 3703:Narcobarbital 3701: 3699: 3696: 3694: 3693:Mephobarbital 3691: 3689: 3686: 3684: 3681: 3679: 3676: 3674: 3673:Cyclobarbital 3671: 3669: 3666: 3664: 3661: 3659: 3656: 3654: 3651: 3649: 3646: 3644: 3641: 3640: 3638: 3636: 3632: 3626: 3623: 3621: 3618: 3616: 3615:Ethchlorvynol 3613: 3611: 3608: 3606: 3603: 3601: 3598: 3596: 3593: 3592: 3590: 3588: 3584: 3581: 3579: 3572: 3567: 3563: 3559: 3552: 3547: 3545: 3540: 3538: 3533: 3532: 3529: 3518: 3508: 3502: 3499: 3497: 3494: 3492: 3489: 3488: 3486: 3482: 3476: 3473: 3472: 3470: 3467: 3463: 3457: 3454: 3453: 3451: 3447: 3441: 3438: 3437: 3435: 3431: 3424: 3421: 3419: 3416: 3414: 3411: 3409: 3406: 3403: 3400: 3399: 3397: 3393: 3387: 3384: 3383: 3381: 3379: 3375: 3369: 3366: 3365: 3363: 3359: 3353: 3350: 3348: 3345: 3344: 3342: 3339: 3335: 3329: 3326: 3323: 3320: 3317: 3314: 3312: 3309: 3307: 3306:Fluclotizolam 3304: 3302: 3301:Flubrotizolam 3299: 3297: 3294: 3292: 3289: 3287: 3284: 3282: 3279: 3277: 3274: 3272: 3269: 3266: 3263: 3261: 3258: 3257: 3255: 3253: 3249: 3243: 3240: 3238: 3235: 3233: 3230: 3229: 3227: 3225: 3221: 3215: 3212: 3210: 3207: 3205: 3202: 3200: 3197: 3195: 3192: 3191: 3189: 3185: 3179: 3176: 3174: 3171: 3169: 3166: 3164: 3161: 3159: 3156: 3154: 3151: 3149: 3146: 3144: 3141: 3139: 3136: 3134: 3131: 3129: 3126: 3124: 3121: 3119: 3116: 3114: 3111: 3109: 3106: 3104: 3101: 3099: 3096: 3094: 3091: 3089: 3086: 3085: 3083: 3079: 3073: 3070: 3067: 3063: 3060: 3058: 3055: 3053: 3050: 3048: 3045: 3043: 3042:Flunitrazolam 3040: 3038: 3037:Flubromazolam 3035: 3033: 3032:Flualprazolam 3030: 3028: 3027:Fluadinazolam 3025: 3023: 3020: 3018: 3015: 3013: 3010: 3007: 3004: 3002: 2999: 2997: 2994: 2993: 2991: 2989: 2985: 2979: 2976: 2974: 2971: 2969: 2966: 2964: 2961: 2959: 2956: 2954: 2951: 2950: 2948: 2944: 2938: 2935: 2933: 2930: 2928: 2925: 2923: 2920: 2918: 2915: 2914: 2912: 2908: 2902: 2899: 2897: 2894: 2892: 2889: 2887: 2884: 2881: 2878: 2875: 2872: 2870: 2867: 2865: 2862: 2860: 2857: 2855: 2852: 2850: 2847: 2845: 2842: 2840: 2837: 2835: 2832: 2829: 2826: 2824: 2821: 2818: 2815: 2813: 2810: 2808: 2805: 2803: 2800: 2798: 2795: 2793: 2790: 2788: 2785: 2783: 2780: 2778: 2775: 2773: 2770: 2768: 2767:Nortetrazepam 2765: 2763: 2760: 2758: 2755: 2753: 2750: 2748: 2745: 2743: 2740: 2738: 2735: 2733: 2731: 2727: 2725: 2722: 2720: 2717: 2715: 2712: 2710: 2707: 2705: 2702: 2699: 2696: 2694: 2691: 2689: 2686: 2684: 2681: 2679: 2676: 2673: 2670: 2668: 2665: 2663: 2660: 2658: 2655: 2653: 2650: 2648: 2647:Flutoprazepam 2645: 2643: 2640: 2638: 2635: 2633: 2632:Flunitrazepam 2630: 2628: 2625: 2623: 2620: 2618: 2617:Flubromazepam 2615: 2613: 2610: 2608: 2605: 2603: 2600: 2598: 2595: 2593: 2590: 2588: 2587:Difludiazepam 2585: 2583: 2580: 2578: 2575: 2572: 2569: 2567: 2564: 2562: 2559: 2557: 2554: 2552: 2549: 2547: 2544: 2542: 2541:Cloniprazepam 2539: 2537: 2534: 2532: 2529: 2527: 2524: 2522: 2519: 2517: 2514: 2512: 2509: 2506: 2503: 2501: 2498: 2496: 2493: 2491: 2490:2-Oxoquazepam 2488: 2487: 2485: 2481: 2477: 2470: 2465: 2463: 2458: 2456: 2451: 2450: 2447: 2425: 2421: 2414: 2408: 2400: 2396: 2392: 2388: 2381: 2373: 2369: 2365: 2361: 2357: 2353: 2352:Life Sciences 2346: 2330: 2326: 2319: 2311: 2307: 2303: 2299: 2292: 2284: 2280: 2276: 2272: 2268: 2264: 2257: 2241: 2237: 2231: 2223: 2219: 2215: 2211: 2204: 2193: 2189: 2185: 2181: 2177: 2173: 2169: 2165: 2161: 2154: 2147: 2139: 2135: 2131: 2127: 2123: 2119: 2112: 2104: 2100: 2096: 2092: 2088: 2084: 2080: 2076: 2069: 2061: 2057: 2053: 2049: 2045: 2041: 2037: 2033: 2026: 2018: 2014: 2010: 2006: 2002: 1998: 1991: 1983: 1979: 1975: 1971: 1967: 1963: 1959: 1955: 1948: 1946: 1944: 1935: 1931: 1927: 1923: 1919: 1915: 1908: 1889: 1885: 1878: 1872: 1864: 1860: 1856: 1852: 1848: 1844: 1837: 1829: 1825: 1821: 1817: 1813: 1809: 1802: 1794: 1790: 1786: 1782: 1778: 1774: 1767: 1760: 1759:public domain 1741: 1739: 1733: 1727: 1719: 1715: 1711: 1707: 1700: 1692: 1688: 1684: 1680: 1676: 1672: 1668: 1664: 1657: 1641: 1637: 1631: 1629: 1627: 1610: 1606: 1602: 1596: 1588: 1584: 1580: 1576: 1569: 1554: 1550: 1544: 1536: 1534:9780190292010 1530: 1526: 1522: 1515: 1507: 1503: 1499: 1495: 1491: 1487: 1483: 1476: 1461: 1460: 1455: 1451: 1445: 1443: 1441: 1439: 1437: 1420: 1416: 1410: 1394: 1390: 1384: 1368: 1364: 1360: 1356: 1350: 1335: 1331: 1327: 1321: 1305: 1301: 1295: 1293: 1288: 1280: 1278: 1274: 1270: 1266: 1256: 1254: 1250: 1246: 1241: 1233: 1231: 1227: 1220: 1205: 1203: 1195: 1192: 1188: 1184: 1174: 1172: 1168: 1164: 1157: 1154: 1151: 1148: 1145: 1142: 1139: 1136: 1135: 1134: 1130: 1120: 1118: 1114: 1110: 1106: 1102: 1098: 1094: 1090: 1086: 1082: 1078: 1074: 1068: 1064: 1058: 1054: 1050: 1046: 1037: 1033: 1029: 1027: 1017: 1015: 1014:birth defects 1011: 1008: 1004: 994: 991: 989: 985: 981: 977: 973: 967: 957: 955: 954:boxed warning 951: 946: 944: 940: 936: 935:hip fractures 932: 928: 927:meta-analysis 920: 916: 912: 908: 905:, dry mouth, 904: 900: 897: 893: 889: 885: 882: 878: 874: 873: 872: 870: 861: 858: 857:disinhibition 852: 850: 846: 842: 838: 834: 830: 820: 816: 814: 810: 806: 802: 798: 794: 790: 786: 782: 778: 774: 770: 766: 756: 749: 740: 735: 734: 731: 724: 715: 714: 711: 704: 697: 693: 692: 690: 687: 682: 675: 673: 669: 642: 640: 636: 631: 627: 623: 620: 618: 616:ECHA InfoCard 612: 604: 600: 599:DTXSID6046763 596: 595: 593: 584: 580: 573: 569: 568: 566: 564: 560: 553: 549: 548: 546: 544: 540: 533: 529: 528: 526: 524: 520: 513: 509: 508: 506: 504: 500: 493: 489: 488: 486: 484: 480: 473: 469: 468: 466: 464: 460: 453: 449: 448: 446: 444: 440: 433: 429: 428: 426: 419: 415: 408: 404: 403: 401: 399: 395: 387: 382: 381: 378: 371: 366: 363: 360: 358: 354: 351:1.5–5.5 hours 350: 348: 341: 338:15–30 minutes 337: 335: 331: 328: 325: 323: 319: 315: 313: 309: 305: 301: 294: 285: 282: 270: 268: 258: 255: 246: 244: 235: 232: 222: 219: 209: 208: 206: 204: 200: 195: 187: 182: 179: 178: 176: 174: 170: 166: 163: 161: 155: 149: 140: 139: 137: 135: 129: 122: 117: 108: 107: 105: 103: 99: 95: 91: 89: 85: 81: 77: 75: 71: 67: 63: 61: 57: 54:Clinical data 52: 48: 43: 39: 34: 26: 22: 7814:Chloroarenes 7755: 7754: 7725: 7582:Lavender oil 7324:Nitric oxide 7244:Cryofluorane 7189:Acetophenone 7147:Methaqualone 7142:Mecloqualone 7137:Mebroqualone 7127:Diproqualone 7122:Cloroqualone 7051:Glutethimide 6855: 6807: 6774: 6736: 6709:Testosterone 6674:Progesterone 6639:Hydroxydione 6588:Androsterone 6515:Acecarbromal 6420:constituents 6207:Cyclarbamate 6197:Carisoprodol 6138: 5969:Metaclazepam 5964:Menitrazepam 5954:Meclonazepam 5949:Lormetazepam 5879:Flutemazepam 5704:Ciclotizolam 5694:Carburazepam 5586:Thiobarbital 5546:Secobarbital 5511:Phetharbital 5491:Nealbarbital 5476:Methohexital 5461:Hexobarbital 5396:Butallylonal 5391:Butobarbital 5346:Barbexaclone 5341:Aprobarbital 5326:Allobarbital 5313:Barbiturates 5280: 5272: 5262:Petrichloral 5133:Valnoctamide 5035:Metaglycodol 5030:Fenpentadiol 4940:Daridorexant 4843:Thioridazine 4794:Trimipramine 4729:Medetomidine 4657:Thioridazine 4608:Trimipramine 4553:Propiomazine 4548:Promethazine 4354:Petrichloral 4339:Kavalactones 4271:Acetophenone 4240:Methaqualone 4235:Mecloqualone 4230:Mebroqualone 4220:Diproqualone 4215:Cloroqualone 4177:Glutethimide 4073:Progesterone 4063:Hydroxydione 3995:Acecarbromal 3909:Carisoprodol 3890: 3851:Lormetazepam 3836:Flutemazepam 3738:Secobarbital 3698:Methohexital 3688:Hexobarbital 3668:Butobarbital 3663:Butabarbital 3653:Aprobarbital 3643:Allobarbital 3635:Barbiturates 3276:Ciclotizolam 3071: 2729: 2719:Metaclazepam 2714:Menitrazepam 2704:Meclonazepam 2693:Lormetazepam 2642:Flutemazepam 2516:Carburazepam 2431:. Retrieved 2424:the original 2419: 2407: 2390: 2386: 2380: 2355: 2351: 2345: 2335:23 September 2333:. Retrieved 2329:the original 2318: 2301: 2297: 2291: 2266: 2262: 2256: 2244:. Retrieved 2240:the original 2230: 2216:(4): 45–57. 2213: 2209: 2203: 2192:the original 2166:(1): 10–29. 2163: 2159: 2146: 2121: 2117: 2111: 2078: 2074: 2068: 2035: 2031: 2025: 2000: 1996: 1990: 1957: 1953: 1917: 1913: 1907: 1895:. Retrieved 1888:the original 1883: 1871: 1846: 1842: 1836: 1811: 1807: 1801: 1776: 1772: 1766: 1746:23 September 1744:. Retrieved 1735: 1726: 1709: 1705: 1699: 1666: 1662: 1656: 1644:. Retrieved 1639: 1613:. Retrieved 1609:the original 1604: 1595: 1578: 1574: 1568: 1556:. Retrieved 1552: 1543: 1524: 1514: 1489: 1485: 1475: 1463:. Retrieved 1457: 1423:. Retrieved 1419:the original 1409: 1397:. Retrieved 1392: 1383: 1371:. Retrieved 1349: 1337:. Retrieved 1329: 1320: 1308:. Retrieved 1303: 1276: 1272: 1268: 1264: 1262: 1242: 1239: 1236:Legal status 1222: 1180: 1177:Pharmacology 1160: 1149:(drowsiness) 1132: 1097:itraconazole 1063:erythromycin 1049:itraconazole 1045:Ketoconazole 1043: 1040:Interactions 1034: 1030: 1023: 1000: 992: 969: 947: 924: 867: 864:Side effects 853: 835:, including 826: 823:Medical uses 817: 807:, sedative, 768: 764: 763: 752:   385: 344:Elimination 203:Legal status 197:Legal status 102:License data 25: 7664:Stiripentol 7659:Seproxetine 7629:Niacinamide 7609:Loreclezole 7430:Avermectins 7394:Vinyl ether 7364:Sevoflurane 7344:Paraldehyde 7294:Halopropane 7117:Afloqualone 7099:Tracazolate 7094:ICI-190,622 7084:Cartazolate 7061:Piperidione 7056:Methyprylon 7023:Fospropofol 6945:Pipequaline 6753:Pazinaclone 6743:Eszopiclone 6599:Cholesterol 6583:Androstenol 6507:Monoureides 6487:Methysticin 6287:Tetrabamate 6267:Pentabamate 6257:Meprobamate 6227:Febarbamate 6192:Carisbamate 6144:Triflubazam 6134:Tolufazepam 6094:Rilmazafone 6089:Remimazolam 6064:Proflazepam 6049:Pivoxazepam 6009:Nitrazepate 5999:Nimetazepam 5934:Lopirazepam 5904:Haloxazolam 5854:Fludiazepam 5799:Doxefazepam 5774:Delorazepam 5754:Clotiazepam 5749:Clorazepate 5714:Cinolazepam 5611:Vinbarbital 5566:Tetrabamate 5521:Probarbital 5501:Phenallymal 5466:Metharbital 5441:Febarbamate 5336:Amobarbital 5237:Isopropanol 5207:Chloralodol 5118:Scopolamine 5062:Guaifenesin 5057:Fenadiazole 5013:Cannabidiol 4987:Mirogabalin 4945:Lemborexant 4922:Tasimelteon 4907:Agomelatine 4866:Risperidone 4812:Mirtazapine 4701:-Adrenergic 4680:Risperidone 4626:Mirtazapine 4576:Etoperidone 4543:Pheniramine 4528:Hydroxyzine 4349:Paraldehyde 4344:Loreclezole 4210:Afloqualone 4192:Piperidione 4182:Methyprylon 4111:Pazinaclone 4091:Eszopiclone 4053:Alphaxolone 4048:Alphadolone 3987:Monoureides 3929:Meprobamate 3866:Nitemazepam 3861:Nimetazepam 3806:Doxefazepam 3791:Cinolazepam 3763:Vinbarbital 3728:Proxibarbal 3713:Phenallymal 3648:Amobarbital 3600:Chloralodol 3501:Rilmazafone 3475:Anthramycin 3368:Lopirazepam 3352:Telenzepine 3311:Fluetizolam 3237:Clotiazepam 3204:Haloxazolam 3148:Remimazolam 3123:I-Iomazenil 3066:Rilmazafone 2937:Triflubazam 2886:Tolufazepam 2797:Proflazepam 2787:Pivoxazepam 2757:Nitrazepate 2747:Nitemazepam 2742:Nimetazepam 2627:Fludiazepam 2592:Doxefazepam 2556:Delorazepam 2546:Clorazepate 2531:Cinolazepam 1884:www.fda.gov 1454:"Triazolam" 1425:29 December 1259:Brand names 1251:and the US 1196:at the GABA 1119:(Atripla). 1085:fluconazole 919:dysesthesia 911:paresthesia 892:tachycardia 679: g·mol 622:100.044.811 368:Identifiers 283:Schedule IV 243:Schedule IV 88:MedlinePlus 60:Trade names 7803:Categories 7697:Topiramate 7687:Terpenoids 7644:Propanidid 7634:Org 25,435 7562:Flupirtine 7557:Fluoxetine 7463:Chloralose 7434:ivermectin 7339:Norflurane 7304:Isoflurane 7249:Desflurane 7239:Chloroform 7199:Aliflurane 7132:Etaqualone 6960:SB-205,384 6890:CP-615,003 6885:CL-218,872 6839:Panadiplon 6829:Lorediplon 6758:Suproclone 6719:Zuranolone 6679:Renanolone 6664:Posovolone 6644:Minaxolone 6634:Ganaxolone 6573:Alfaxalone 6568:Alfadolone 6558:Acebrochol 6525:Bromisoval 6403:Metomidate 6390:Imidazoles 6350:Hispidulin 6302:Flavonoids 6262:Nisobamate 6252:Mebutamate 6222:Ethinamate 6217:Emylcamate 6184:Carbamates 6154:Tuclazepam 6129:Tetrazepam 6084:Reclazepam 6059:Premazepam 6039:Phenazepam 6019:Nordazepam 6014:Nitrazolam 6004:Nitrazepam 5984:Motrazepam 5939:Loprazolam 5929:Lofendazam 5914:Imidazenil 5874:Flutazolam 5869:Flurazepam 5839:Fletazepam 5794:Dimdazenil 5789:Diclazepam 5769:Cyprazepam 5759:Cloxazolam 5739:Clonazolam 5734:Clonazepam 5724:Climazolam 5684:Brotizolam 5679:Bromazolam 5674:Bromazepam 5669:Bretazenil 5664:Bentazepam 5654:Arfendazam 5649:Alprazolam 5644:Adinazolam 5616:Vinylbital 5596:Thiopental 5471:Methitural 5386:Buthalital 5381:Butalbital 5232:Isobutanol 5086:Metaxalone 5076:Mephenesin 4997:Pregabalin 4977:Gabapentin 4950:Suvorexant 4885:Niaprazine 4861:Quetiapine 4856:Olanzapine 4739:Tizanidine 4734:Romifidine 4724:Lofexidine 4714:Detomidine 4675:Quetiapine 4670:Olanzapine 4581:Nefazodone 4523:Doxylamine 4508:Captodiame 4319:Chloralose 4283:compounds 4225:Etaqualone 4121:Suproclone 4101:Lirequinil 4068:Minaxolone 4058:Eltanolone 4038:Acebrochol 4005:Bromisoval 3972:Metomidate 3959:Imidazoles 3919:Ethinamate 3914:Emylcamate 3901:Carbamates 3876:Nitrazolam 3871:Nitrazepam 3846:Loprazolam 3831:Flurazepam 3801:Clonazolam 3796:Climazolam 3786:Brotizolam 3768:Vinylbital 3753:Thiopental 3440:Premazepam 3423:Zometapine 3347:Olanzapine 3316:Israpafant 3281:Clotizolam 3271:Brotizolam 3232:Bentazepam 3199:Flutazolam 3194:Cloxazolam 3173:Sarmazenil 3133:Loprazolam 3118:Imidazenil 3108:Flumazenil 3093:Climazolam 3088:Bretazenil 3062:Rilmazolam 3052:Phenazolam 3047:Nitrazolam 3017:Clonazolam 3012:Bromazolam 3006:Balovaptan 3001:Alprazolam 2996:Adinazolam 2973:Talampanel 2963:GYKI-52895 2958:GYKI-52466 2932:Lofendazam 2917:Arfendazam 2896:Tuclazepam 2869:Tetrazepam 2812:Reclazepam 2777:Phenazepam 2762:Nordazepam 2752:Nitrazepam 2724:Motrazepam 2678:Kenazepine 2637:Flurazepam 2622:Fletazepam 2582:Diclazepam 2571:Devazepide 2551:Cyprazepam 2536:Clonazepam 2505:BMS-906024 2500:Bromazepam 2420:Green list 1897:15 January 1646:23 October 1399:30 January 1339:22 October 1310:24 October 1283:References 1265:Apo-Triazo 1247:under the 1226:alprazolam 1217:See also: 1187:lipophilic 1147:Somnolence 1127:See also: 1105:rifampicin 1101:nefazodone 1077:cimetidine 1057:nitrazepam 1003:alcoholics 907:dermatitis 896:depression 877:somnolence 845:anesthesia 805:anxiolytic 777:depressant 684:3D model ( 672:Molar mass 552:CHEBI:9674 512:1HM943223R 483:ChemSpider 443:IUPHAR/BPS 407:28911-01-5 398:CAS Number 377:IUPAC name 322:Metabolism 292: N IV 254:Anlage III 167:(by mouth) 7756:See also: 7718:valerenol 7639:Phenytoin 7619:Monastrol 7577:Lanthanum 7572:KRM-II-81 7535:Fenamates 7530:Etifoxine 7525:Etazepine 7520:Efavirenz 7478:Darigabat 7374:Teflurane 7359:Roflurane 7354:Propylene 7299:Halothane 7284:Fluroxene 7269:Enflurane 7172:Volatiles 7089:Etazolate 7000:Viqualine 6955:RWJ-51204 6920:L-838,417 6910:Imepitoin 6880:CGS-20625 6875:CGS-13767 6860:Adipiplon 6834:Ocinaplon 6796:Saripidem 6791:Necopidem 6768:Zopiclone 6763:Suriclone 6748:Pagoclone 6654:ORG-21465 6649:ORG-20599 6540:Ectylurea 6530:Carbromal 6408:Propoxate 6398:Etomidate 6325:Baicalein 6282:Styramate 6277:Procymate 6247:Lorbamate 6232:Felbamate 6202:Clocental 6174:Zomebazam 6169:Zolazepam 6164:Zapizolam 6159:Uldazepam 6139:Triazolam 6124:Temazepam 6119:Sulazepam 6109:Ro48-8684 6104:Ro48-6791 6099:Ripazepam 6069:Pyrazolam 6044:Pinazepam 5994:Nifoxipam 5979:Midazolam 5974:Mexazolam 5959:Medazepam 5944:Lorazepam 5924:Ketazolam 5919:Irazepine 5909:Iclazepam 5899:Halazepam 5894:Gidazepam 5889:Fosazepam 5809:Estazolam 5804:Elfazepam 5779:Demoxepam 5709:Cinazepam 5689:Camazepam 5659:Avizafone 5581:Thiamylal 5516:Primidone 5446:Heptabarb 5436:Eterobarb 5401:Carbubarb 5298:Triclofos 5197:Brometone 5123:Trazodone 5064:-related 4917:Ramelteon 4912:Melatonin 4899:Melatonin 4807:Mianserin 4774:Trazodone 4709:Clonidine 4621:Mianserin 4586:Trazodone 4538:Perlapine 4381:Triclofos 4334:Gaboxadol 4141:Zopiclone 4126:Suriclone 4116:Saripidem 4106:Necopidem 4020:Ectylurea 4015:Carbromal 3977:Propoxate 3967:Etomidate 3944:Procymate 3891:Triazolam 3886:Temazepam 3856:Midazolam 3811:Estazolam 3748:Thiamylal 3683:Heptabarb 3562:sedatives 3558:Hypnotics 3496:Avizafone 3418:Zomebazam 3413:Zolazepam 3408:Ripazepam 3402:Razobazam 3386:Zapizolam 3328:Metizolam 3242:Ro09-9212 3209:Mexazolam 3168:Ro4938581 3163:Ro48-8684 3158:Ro48-6791 3153:Ro15-4513 3138:Midazolam 3128:L-655,708 3072:Triazolam 3057:Pyrazolam 3022:Estazolam 2978:Tofisopam 2968:Nerisopam 2953:Girisopam 2901:Uldazepam 2880:Timelotem 2874:Tifluadom 2864:Temazepam 2859:Sulazepam 2854:SH-I-048A 2849:Ro20-8552 2844:Ro20-8065 2839:Ro07-9749 2834:Ro07-5220 2823:Ro05-4082 2817:RO4491533 2782:Pinazepam 2737:Nifoxipam 2709:Medazepam 2698:Lufuradom 2688:Lorazepam 2683:Ketazolam 2672:Irazepine 2667:Iclazepam 2662:Halazepam 2657:Gidazepam 2652:Fosazepam 2597:Elfazepam 2561:Demoxepam 2526:Cinazepam 2511:Camazepam 2246:3 January 1663:CNS Drugs 1615:6 January 1558:7 October 1373:16 August 1304:Drugs.com 1230:lorazepam 1109:ritonavir 1093:isoniazid 1081:diltiazem 939:Confusion 931:cognitive 881:dizziness 791:to treat 765:Triazolam 572:ChEMBL646 357:Excretion 346:half-life 158:Routes of 132:Pregnancy 121:Triazolam 80:Monograph 74:Drugs.com 30:Triazolam 7793:Medicine 7744:TCS-1205 7739:TCS-1105 7729:α-Pinene 7702:Valerian 7677:tetronal 7654:Safranal 7603:obovatol 7599:magnolol 7595:honokiol 7425:Alogabat 7420:AA-29504 7369:Synthane 7329:Nitrogen 7309:Kerosine 7289:Gasoline 7279:Ethylene 7219:Centalun 7214:Butylene 7028:Propofol 6990:U-89843A 6970:TGSC01AA 6940:NS-11394 6905:GBLD-345 6870:CGS-9896 6865:CGS-8216 6849:Zaleplon 6844:Taniplon 6824:Indiplon 6819:Fasiplon 6814:Divaplon 6801:Zolpidem 6704:SAGE-872 6699:SAGE-689 6694:SAGE-516 6689:SAGE-324 6684:SAGE-105 6592:Certain 6535:Capuride 6497:Yangonin 6374:baicalin 6370:Skullcap 6360:Luteolin 6335:Catechin 6330:Baicalin 6320:Apigenin 6292:Tybamate 6079:Quazepam 6074:QH-II-66 6054:Prazepam 6034:Oxazolam 6029:Oxazepam 5829:Etizolam 5784:Diazepam 5764:CP-1414S 5729:Clobazam 5719:Clazolam 5606:Valofane 5561:Talbutal 5551:Sigmodal 5456:Hexethal 5351:Barbital 5331:Alphenal 5321:(-)-DMBB 5267:Propanol 5257:Pentanol 5247:Methanol 5189:Alcohols 5107:morphine 5098:Midaflur 5018:Cannabis 4992:Phenibut 4744:Xylazine 4473:Phenibut 4443:Baclofen 4369:Tetronal 4304:Centalun 4159:Propofol 4136:Zolpidem 4131:Zaleplon 4096:Indiplon 4010:Capuride 3949:Tybamate 3881:Quazepam 3743:Talbutal 3658:Barbital 3587:Alcohols 3519:ligands) 3517:receptor 3456:Clazolam 3296:Etizolam 3214:Oxazolam 3113:GL-II-73 2927:CP-1414S 2922:Clobazam 2828:Ro5-4864 2807:QH-II-66 2802:Quazepam 2792:Prazepam 2772:Oxazepam 2577:Diazepam 2433:23 March 2399:16336040 2222:16380358 2180:14561946 2103:22742117 2060:39127216 2017:16860264 1982:24226217 1934:20171127 1863:19900604 1793:10533351 1691:25592318 1683:15089115 1640:DailyMed 1553:ClinCalc 1506:18855614 1465:23 March 1459:DrugBank 1452:(2006). 1367:Archived 1156:Seizures 1123:Overdose 1073:Caffeine 1007:comorbid 915:tinnitus 903:diarrhea 888:euphoria 849:quazepam 841:adjuvant 829:insomnia 797:hypnotic 789:sedative 755:(verify) 463:DrugBank 231:Class B1 173:ATC code 134:category 116:DailyMed 7691:borneol 7689:(e.g., 7681:trional 7671:(e.g., 7589:(e.g., 7587:Lignans 7537:(e.g., 7495:(e.g., 7440:Bromide 7432:(e.g., 7415:α-EMTBL 7379:Toluene 7349:Propane 7224:Chloral 7204:Benzene 7184:Acetone 7015:Phenols 7005:Y-23684 6995:U-90042 6980:TPA-023 6965:SX-3228 6950:ROD-188 6935:NS-2710 6930:NS-2664 6915:JM-1232 6900:ELB-139 6895:CTP-354 6781:Alpidem 6380:Wogonin 6355:Linarin 5834:FG-8205 5541:Reposal 5242:Menthol 5202:Butanol 5105:(e.g., 5103:Opioids 5052:Evoxine 4789:Doxepin 4603:Doxepin 4478:Tolibut 4374:Trional 4281:Bromide 4151:Phenols 3733:Reposal 3265:Apafant 3143:PWZ-029 3103:FG-8205 3098:EVT-201 2372:2983169 2310:2570451 2283:9153780 2188:1543185 2138:1351673 2095:9014234 2052:7995001 1974:3529832 1718:2068441 1587:7901174 1269:Halcion 1167:alcohol 1163:opioids 1020:Elderly 943:amnesia 837:jet lag 801:amnesic 769:Halcion 639:Formula 472:DB00897 418:PubChem 280:WARNING 267:Class C 241:: 189:) 183: ( 181:N05CD05 147: C 118::  94:a684004 64:Halcion 7779:Portal 7624:Niacin 7209:Butane 7162:SL-164 7033:Thymol 6975:TP-003 6856:Others 6659:P1-185 6619:5β-DHP 6614:5α-DHP 6609:3α-DHP 6457:Kavain 6365:Rc-OMe 5006:Others 4932:Orexin 4878:Others 4868:, etc. 4845:, etc. 4814:, etc. 4796:, etc. 4682:, etc. 4659:, etc. 4628:, etc. 4610:, etc. 4264:Others 4255:SL-164 2397:  2370:  2308:  2281:  2220:  2186:  2178:  2136:  2101:  2093:  2058:  2050:  2015:  1980:  1972:  1932:  1861:  1828:430730 1826:  1791:  1716:  1689:  1681:  1585:  1531:  1504:  1355:Anvisa 1277:Trilam 1275:, and 1111:, and 811:, and 775:(CNS) 710:SMILES 677:343.21 563:ChEMBL 532:D00387 362:Kidney 277: 265: 229: 216: 114:  7483:DEABL 7176:gases 6985:TP-13 6714:THDOC 6604:DHDOC 5128:UMB68 4448:GABOB 2427:(PDF) 2416:(PDF) 2195:(PDF) 2184:S2CID 2156:(PDF) 2099:S2CID 2056:S2CID 1978:S2CID 1891:(PDF) 1880:(PDF) 1740:(FDA) 1736:U.S. 1687:S2CID 1273:Hypam 1169:, or 730:InChI 686:JSmol 543:ChEBI 327:Liver 6786:DS-1 6418:Kava 6345:EGCG 5281:tert 5273:tert 5176:GABA 4968:VDCC 4754:5-HT 4417:GABA 3595:2M2B 3575:GABA 3566:N05C 3513:GABA 2435:2006 2395:PMID 2368:PMID 2337:2007 2306:PMID 2279:PMID 2248:2010 2218:PMID 2176:PMID 2134:PMID 2091:PMID 2048:PMID 2013:PMID 1970:PMID 1930:PMID 1899:2022 1859:PMID 1824:PMID 1808:JAMA 1789:PMID 1748:2020 1714:PMID 1679:PMID 1648:2020 1617:2019 1583:PMID 1560:2022 1529:ISBN 1502:PMID 1467:2006 1427:2008 1401:2023 1375:2023 1341:2023 1312:2020 1194:GABA 1137:Coma 1047:and 941:and 831:and 523:KEGG 503:UNII 492:5355 452:7313 432:5556 306:data 165:Oral 70:AHFS 7515:DS2 6624:DHT 6340:EGC 4468:GVL 4463:GBL 4453:GHB 3322:JQ1 2360:doi 2271:doi 2168:doi 2126:doi 2083:doi 2040:doi 2005:doi 1962:doi 1958:329 1922:doi 1851:doi 1816:doi 1812:241 1781:doi 1671:doi 1521:"B" 1494:doi 1334:FDA 1228:or 588:EPA 422:CID 186:WHO 7805:: 7765:• 7761:• 7716:, 7712:, 7708:, 7679:, 7675:, 7601:, 7597:, 7593:, 7549:, 7545:, 7541:, 7507:, 7503:, 7499:, 7450:, 7446:, 6858:: 6812:: 6779:: 6741:: 4756:2A 2418:. 2391:66 2389:. 2366:. 2356:36 2354:. 2302:78 2300:. 2277:. 2267:86 2265:. 2214:18 2212:. 2182:. 2174:. 2164:37 2162:. 2158:. 2132:. 2122:70 2120:. 2097:. 2089:. 2079:50 2077:. 2054:. 2046:. 2036:56 2034:. 2011:. 1999:. 1976:. 1968:. 1956:. 1942:^ 1928:. 1918:14 1916:. 1882:. 1857:. 1847:67 1845:. 1822:. 1810:. 1787:. 1777:39 1775:. 1734:. 1710:80 1708:. 1685:. 1677:. 1667:18 1665:. 1638:. 1625:^ 1603:. 1579:13 1577:. 1551:. 1523:. 1500:. 1488:. 1484:. 1456:. 1435:^ 1391:. 1332:. 1328:. 1302:. 1291:^ 1271:, 1267:, 1255:. 1173:. 1165:, 1107:, 1103:, 1099:, 1095:, 1091:, 1087:, 1083:, 1079:, 1016:. 982:, 978:, 937:. 917:, 913:, 890:, 879:, 803:, 656:Cl 653:12 647:17 288:UN 273:US 261:UK 249:DE 238:CA 225:BR 218:S4 212:AU 143:AU 111:US 7781:: 7720:) 7693:) 7683:) 7605:) 7553:) 7511:) 7454:) 7436:) 7174:/ 6376:) 5223:) 5219:( 5179:A 5167:e 5160:t 5153:v 5109:) 4965:δ 4963:2 4961:α 4699:2 4697:α 4490:1 4488:H 4459:) 4455:( 4419:B 3577:A 3568:) 3564:( 3560:/ 3550:e 3543:t 3536:v 3515:A 3468:* 3425:* 3404:* 3340:* 3324:* 3318:* 3267:* 3068:) 3008:* 2882:* 2876:* 2830:* 2819:* 2730:N 2700:* 2674:* 2573:* 2507:* 2468:e 2461:t 2454:v 2437:. 2401:. 2374:. 2362:: 2339:. 2312:. 2285:. 2273:: 2250:. 2224:. 2170:: 2140:. 2128:: 2105:. 2085:: 2062:. 2042:: 2019:. 2007:: 2001:4 1984:. 1964:: 1936:. 1924:: 1901:. 1865:. 1853:: 1830:. 1818:: 1795:. 1783:: 1761:. 1750:. 1720:. 1693:. 1673:: 1650:. 1619:. 1589:. 1562:. 1537:. 1508:. 1496:: 1490:9 1469:. 1429:. 1403:. 1377:. 1343:. 1314:. 1198:A 1069:. 688:) 665:4 662:N 659:2 650:H 644:C 590:) 586:( 386:H 290:: 275:: 263:: 227:: 214:: 145:: 72:/ 23:.

Index

Halcyon (disambiguation)


Trade names
AHFS
Drugs.com
Monograph
MedlinePlus
a684004
License data
DailyMed
Triazolam
Pregnancy
category

Routes of
administration

Oral
ATC code
N05CD05
WHO
Legal status
S4
Class B1
Schedule IV
Anlage III
Class C
WARNING
Pharmacokinetic
Bioavailability
Metabolism
Liver
Onset of action

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