605:"The American Heart Association recommends aspirin use for patients who've had a myocardial infarction (heart attack), unstable angina, ischemic stroke (caused by blood clot) or transient ischemic attacks (TIAs or "little strokes"), if not contraindicated. This recommendation is based on sound evidence from clinical trials showing that aspirin helps prevent the recurrence of such events as heart attack, hospitalization for recurrent angina, second strokes, etc. (secondary prevention). Studies show aspirin also helps prevent these events from occurring in people at high risk (primary prevention)."
250:; therefore, there is a balance shift toward inhibition of vasoconstriction and platelet aggregation. It is believed that this shift in balance lowers the incidence of myocardial infarction (heart attack) and stroke. Vasoconstriction and, perhaps, various proinflammatory effects exerted by TxA on tissue microvasculature, is probable reason why the TxA is pathogenic in various diseases, such as ischemia-reperfusion injury., hepatic inflammatory processes, acute hepatotoxicity etc. TxB2, a stable degradation product of TxA2, plays a role in acute hepatoxicity induced by acetaminophen.
97:
89:
31:
41:
313:
can induce near-complete suppression of platelet thromboxane throughout the dosing interval and appears not to increase cardiovascular disease (CVD) risk, whereas other high-dose NSAID (non-steroidal-anti-inflammatory) regimens have only transient effects on platelet
189:, platelets stick to the damaged lining of the vessel and to each other within seconds and form a plug. These "Sticky platelets" secrete several chemicals, including thromboxane A2 that stimulate vasoconstriction, reducing blood flow at the site.
284:. This anticoagulant property makes aspirin useful for reducing the incidence of heart attacks. 40 mg of aspirin a day is able to inhibit a large proportion of maximum thromboxane A
1160:
182:, a related compound. The mechanism of secretion of thromboxanes from platelets is still unclear. They act in the formation of blood clots and reduce blood flow to the site of a clot.
2193:
269:
acts by inhibiting the ability of the COX enzyme to synthesize the precursors of thromboxane within platelets. Low-dose, long-term aspirin use irreversibly blocks the formation of
660:
Dockens, RC; Santone, KS; Mitroka, JG; Morrison, RA; Jemal, M; Greene, DS; Barbhaiya, RH (Aug 2000). "Disposition of radiolabeled ifetroban in rats, dogs, monkeys, and humans".
617:
Tohgi, H; S Konno; K Tamura; B Kimura; K Kawano (1992). "Effects of low-to-high doses of aspirin on platelet aggregability and metabolites of thromboxane A2 and prostacyclin".
736:
Ratti, S; Quarato, P; Casagrande, C; Fumagalli, R; Corsini, A (1998). "Picotamide, an antithromboxane agent, inhibits the migration and proliferation of arterial myocytes".
2504:
1564:
2645:
288:
release provoked acutely, with the prostaglandin I2 synthesis being little affected; however, higher doses of aspirin are required to attain further inhibition.
689:"Vascular and upper gastrointestinal effects of non-steroidal anti-inflammatory drugs: meta-analyses of individual participant data from randomised trials"
258:
Thromboxane inhibitors are broadly classified as either those that inhibit the synthesis of thromboxane, or those that inhibit the target effect of it.
3405:
3375:
3206:
207:), produced by activated platelets, has prothrombotic properties, stimulating activation of new platelets as well as increasing platelet aggregation.
2411:
2031:
3258:
3238:
2794:
2744:
3564:
3029:
2919:
2914:
2899:
2834:
2784:
2739:
2304:
3971:
3802:
3792:
3216:
2894:
2874:
2859:
2849:
2829:
2824:
2779:
2754:
2719:
2565:
2396:
2174:
2072:
2011:
1972:
1771:
1761:
1669:
1557:
413:
Ito Y (2003). "Effects of selective cyclooxygenase inhibitors on ischemia/reperfusion-induced hepatic microcirculatory dysfunction in mice".
4001:
3996:
3961:
3936:
3797:
3658:
3515:
3116:
3111:
2909:
2889:
2884:
2879:
2864:
2854:
2844:
2819:
2809:
2804:
2799:
2789:
2774:
2769:
2729:
2688:
2668:
2625:
2620:
2605:
2595:
2590:
2575:
2454:
2376:
2331:
2245:
2221:
2211:
1659:
3986:
3941:
3752:
3698:
3683:
3532:
3243:
3191:
3076:
2924:
2869:
2839:
2814:
2764:
2759:
2749:
2734:
2683:
2678:
2635:
2570:
2560:
2530:
2474:
2444:
2401:
2391:
2240:
2164:
2016:
1929:
1726:
3991:
3966:
3956:
3807:
3782:
3767:
3732:
3708:
3703:
3454:
2904:
2724:
2658:
2630:
2615:
2610:
2585:
2201:
2169:
2149:
2092:
1977:
1900:
1895:
1890:
1885:
1721:
1716:
456:
Katagiri H (2004). "Role of thromboxane derived from COX-1 and -2 in hepatic microcirculatory dysfunction during endotoxemia in mice".
339:
4094:
4011:
3727:
3673:
3668:
2703:
2550:
2459:
2416:
1967:
1880:
1766:
1746:
1741:
1736:
773:"[Ridogrel, a new platelet antiaggregant molecule with a double mechanism of action. A pharmacological and clinical profile]"
3873:
3777:
3772:
2580:
2545:
2421:
2381:
1550:
2663:
2512:
1103:
129:
tend to have increased thromboxane production, and analogs of thromboxane act as bronchoconstrictors in patients with asthma.
844:
379:
1066:
2540:
323:
291:
261:
Thromboxane synthesis inhibitors, in turn, can be classified regarding which step in the synthesis they inhibit:
4087:
17:
1679:
1622:
359:
2102:
1987:
1910:
1803:
142:
4044:
1785:
1604:
837:
3881:
3862:
3817:
2259:
816:
1587:
606:
306:
antagonizes this receptor too, but has various other mechanisms of antiplatelet activity as well.
336:
has activity both as a thromboxane synthase inhibitor and as a thromboxane receptor antagonist.
3923:
3843:
599:
231:
104:
686:
573:
Cavar I (2010). "The role of prostaglandin E2 in acute acetaminophen hepatotoxicity in mice".
3900:
2356:
1593:
1525:
1319:
1217:
972:
211:
186:
4116:
4039:
3161:
3014:
2484:
830:
542:"Anti-thromboxane B2 antibodies protect against acetaminophen-induced liver injury in mice"
295:
138:
2322:
2231:
8:
2989:
1262:
812:
3851:
1579:
713:
688:
642:
481:
438:
401:
371:
235:
175:
749:
704:
3385:
3054:
3024:
792:
784:
753:
718:
669:
634:
582:
522:
473:
430:
375:
210:
Platelet aggregation is achieved by mediating expression of the glycoprotein complex
646:
485:
442:
4067:
4059:
4054:
3358:
2944:
2435:
2314:
2140:
2131:
2063:
2054:
2046:
1948:
1939:
1861:
1852:
1703:
1641:
1516:
1496:
1476:
1468:
1419:
1352:
1313:
1268:
961:
950:
928:
902:
867:
745:
708:
700:
626:
553:
512:
465:
422:
367:
149:
116:
112:
1542:
501:"Role of thromboxane in producing hepatic injury during a hepatic stress disorder"
3915:
3847:
3757:
3432:
3410:
3380:
2077:
941:
318:
and have been found to be associated "with a small but definite vascular hazard".
164:
230:
It is believed that the vasoconstriction caused by thromboxanes plays a role in
3437:
3390:
2955:
2517:
1576:
1453:
1445:
1404:
1384:
1376:
1368:
1335:
1327:
1300:
1292:
1284:
1276:
1127:
1119:
1111:
1090:
1082:
1033:
1025:
517:
500:
270:
197:
92:
Enzymes and substrates associated with thromoboxane and prostacyclin synthesis.
66:
62:
44:
34:
630:
4110:
4034:
3718:
3503:
3400:
3278:
3263:
3196:
3126:
886:
788:
3574:
3491:
3417:
3395:
3348:
3283:
3253:
3233:
3228:
3151:
3039:
2464:
2426:
2294:
2121:
1957:
1842:
1649:
1427:
1360:
1346:
993:
772:
722:
673:
586:
526:
477:
434:
303:
179:
796:
757:
687:
Coxib and traditional NSAID Trialists' (CNT) Collaboration (30 May 2013).
638:
167:
and a potent hypertensive agent, and it facilitates platelet aggregation.
4049:
3951:
3892:
3762:
3747:
3688:
3653:
3631:
3611:
3559:
3544:
3486:
3444:
3370:
3338:
3323:
3156:
3141:
3066:
3004:
2999:
2673:
2346:
2309:
2284:
2279:
2126:
2082:
2041:
2036:
1934:
1870:
1847:
1837:
1756:
1731:
1698:
1664:
1245:
1050:
659:
558:
541:
171:
58:
88:
3981:
3742:
3713:
3693:
3646:
3641:
3626:
3601:
3569:
3537:
3508:
3464:
3363:
3313:
3308:
3303:
3298:
3273:
3186:
3181:
3121:
3106:
3086:
3071:
3044:
3019:
3009:
2994:
2984:
2698:
2653:
2640:
2555:
2341:
2336:
2289:
2226:
2206:
2159:
1751:
1573:
1509:
877:
853:
333:
327:
218:
binds these receptors on adjacent platelets, further strengthening the
215:
96:
77:
469:
426:
30:
4006:
3946:
3678:
3636:
3621:
3616:
3606:
3596:
3591:
3586:
3581:
3496:
3479:
3474:
3469:
3353:
3333:
3328:
3293:
3288:
3248:
3221:
3176:
3171:
3166:
3146:
3101:
3096:
3059:
3049:
2974:
2693:
2600:
2449:
2386:
2299:
2216:
2021:
2006:
1827:
1822:
1438:
299:
146:
108:
3839:
3834:
3663:
3525:
3520:
3459:
3449:
3427:
3422:
3343:
3318:
3268:
3211:
3201:
3136:
3131:
3091:
2406:
2026:
1832:
1397:
1200:
1192:
1184:
1176:
310:
281:
277:
3976:
3787:
3554:
3081:
3034:
2979:
2525:
1236:
1229:
1225:
266:
40:
3737:
2938:
735:
126:
54:
822:
402:
Rat kidney thromboxane receptor: molecular cloning, signal ...
3549:
1489:
1144:
315:
70:
69:. The distinguishing feature of thromboxanes is a 6-membered
616:
322:
The inhibitors of the target effects of thromboxane are the
185:
If the cap of a vulnerable plaque erodes or ruptures, as in
302:
is a potent and selective thromboxane receptor antagonist.
219:
76:
Thromboxane is named for its role in blood clot formation (
771:
Di Perri, T.; Notari, M.; Assogna, G. (October 1991).
770:
192:
1680:
1623:
1572:
2961:
2103:
1988:
1911:
1804:
1786:
1605:
4108:
3882:
3863:
3818:
2260:
238:are metabolized to produce higher levels of TxA
214:in the cell membrane of platelets. Circulating
3924:
3901:
2357:
1558:
838:
603:Aspirin in Heart Attack and Stroke Prevention
2485:
653:
357:
1565:
1551:
845:
831:
498:
455:
358:Chung, Kian Fan; Barnes, Peter J. (2009).
242:, which is relatively less potent than TxA
137:Thromboxane acts by binding to any of the
815:at the U.S. National Library of Medicine
712:
557:
516:
253:
95:
87:
39:
29:
572:
539:
14:
4109:
2956:
1546:
826:
412:
3579:Selective COX-2 inhibitors (coxibs):
280:, producing an inhibitory effect on
1688:Tooltip Prostaglandin D2 receptor 2
1631:Tooltip Prostaglandin D2 receptor 1
298:) in the synthesis of thromboxane.
24:
3550:AM-404 (N-arachidonoylaminophenol)
3368:Anthranilic acids (fenamic acids):
3020:Mesalazine (5-aminosalicylic acid)
2111:Tooltip Prostaglandin EP4 receptor
1996:Tooltip Prostaglandin EP3 receptor
1919:Tooltip Prostaglandin EP2 receptor
1812:Tooltip Prostaglandin EP1 receptor
372:10.1016/B978-0-12-374001-4.00052-3
193:Role of A2 in platelet aggregation
25:
4128:
4040:γ-Linolenic acid (gamolenic acid)
3386:Meclofenamic acid (meclofenamate)
1795:Tooltip Prostaglandin E2 receptor
1614:Tooltip Prostaglandin D2 receptor
1161:Arachidonic acid 15-hydroperoxide
806:
61:. The two major thromboxanes are
4095:Leukotriene signaling modulators
3887:Tooltip Prostaglandin F synthase
3868:Tooltip Prostaglandin E synthase
3827:Tooltip Prostaglandin D synthase
2269:Tooltip Prostaglandin F receptor
1067:Arachidonic acid 5-hydroperoxide
738:European Journal of Pharmacology
3406:Talinflumic acid (talinflumate)
3396:Morniflumic acid (morniflumate)
3376:Floctafenic acid (floctafenate)
3359:Tiaprofenic acid (tiaprofenate)
852:
764:
729:
680:
662:Drug Metabolism and Disposition
324:thromboxane receptor antagonist
292:Thromboxane synthase inhibitors
3929:Tooltip Thromboxane A synthase
2980:Aspirin (acetylsalicylic acid)
2194:16,16-Dimethyl Prostaglandin E
610:
593:
566:
533:
492:
449:
406:
395:
351:
13:
1:
4088:Receptor/signaling modulators
3910:Tooltip Prostacyclin synthase
3411:Tolfenamic acid (tolfenamate)
3381:Flufenamic acid (flufenamate)
3371:Etofenamic acid (etofenamate)
2427:Prostacyclin (prostaglandin I
2366:Tooltip Prostacyclin receptor
777:Recenti Progressi in Medicina
750:10.1016/S0014-2999(98)00467-1
705:10.1016/S0140-6736(13)60900-9
345:
83:
53:is a member of the family of
2494:Tooltip Thromboxane receptor
601:American Heart Association:
225:
158:
132:
7:
3560:Paracetamol (acetaminophen)
3391:Mefenamic acid (mefenamate)
3045:Salicylate (salicylic acid)
998:(Prostacyclin/Epoprostenol)
143:G-protein-coupled receptors
10:
4133:
3239:Bucloxic acid (blucloxate)
3157:Indometacin (indomethacin)
518:10.1001/archsurg.140.8.801
294:inhibit the final enzyme (
4079:
4024:
3922:
3899:
3880:
3861:
3816:
3401:Niflumic acid (niflumate)
2954:
2937:
2712:
2505:Carbocyclic thromboxane A
2483:
2355:
2258:
2183:
2101:
1986:
1909:
1802:
1784:
1678:
1621:
1603:
1586:
1254:
1216:
1169:
1153:
1143:
1102:
1075:
1059:
1049:
1015:
986:
940:
921:
914:
895:
885:
876:
860:
631:10.1161/01.STR.23.10.1400
3719:Menatetrenone (vitamin K
3542:Aminophenols (anilines):
817:Medical Subject Headings
4045:Dihomo-γ-linolenic acid
3442:Enolic acids (oxicams):
2985:Benorilate (benorylate)
3844:selenium tetrachloride
546:Journal of Xenobiotics
360:"Mediator Antagonists"
254:Thromboxane inhibitors
105:Thromboxane-A synthase
101:
93:
47:
37:
3513:Aminonicotinic acids:
265:The widely used drug
187:myocardial infarction
139:thromboxane receptors
107:, an enzyme found in
100:Eicosanoid synthesis.
99:
91:
43:
33:
3162:Indometacin farnesil
3015:Magnesium salicylate
2646:Pinane thromboxane A
2407:Iloprost (ciloprost)
2027:Iloprost (ciloprost)
1833:Iloprost (ciloprost)
559:10.4081/xeno.2011.e8
342:is another example.
296:thromboxane synthase
282:platelet aggregation
2990:Carbasalate calcium
1263:bronchoconstriction
499:Yokoyama Y (2005).
236:Omega-3 fatty acids
232:Prinzmetal's angina
3852:selenium disulfide
3484:4-Aminoquinolines:
575:Histol Histopathol
176:circulatory system
102:
94:
73:-containing ring.
48:
38:
4104:
4103:
4020:
4019:
3055:Sodium salicylate
3025:Methyl salicylate
2948:
2933:
2932:
2254:
2253:
1780:
1779:
1597:
1540:
1539:
1212:
1211:
1139:
1138:
1045:
1044:
1011:
1010:
1007:
1006:
625:(10): 1400–1403.
470:10.1002/hep.20000
427:10.1159/000072174
163:Thromboxane is a
16:(Redirected from
4124:
4055:Arachidonic acid
3930:
3926:
3911:
3907:
3888:
3884:
3869:
3865:
3828:
3824:
3651:Others/unsorted:
3226:Propionic acids:
3207:Sulindac sulfide
2972:Salicylic acids:
2963:
2958:
2952:
2951:
2942:
2495:
2491:
2367:
2363:
2270:
2266:
2112:
2108:
1997:
1993:
1920:
1916:
1813:
1809:
1800:
1799:
1796:
1792:
1689:
1685:
1632:
1628:
1619:
1618:
1615:
1611:
1601:
1600:
1591:
1567:
1560:
1553:
1544:
1543:
1314:vasoconstriction
1151:
1150:
1057:
1056:
919:
918:
893:
892:
883:
882:
868:Arachidonic acid
847:
840:
833:
824:
823:
801:
800:
768:
762:
761:
733:
727:
726:
716:
699:(9894): 769–79.
684:
678:
677:
657:
651:
650:
614:
608:
597:
591:
590:
570:
564:
563:
561:
540:Cavar I (2011).
537:
531:
530:
520:
496:
490:
489:
453:
447:
446:
410:
404:
399:
393:
392:
390:
388:
355:
122:to thromboxane.
113:arachidonic acid
21:
4132:
4131:
4127:
4126:
4125:
4123:
4122:
4121:
4107:
4106:
4105:
4100:
4075:
4071:
4068:Prostaglandin H
4063:
4060:Prostaglandin G
4016:
3928:
3918:
3916:Tranylcypromine
3909:
3905:
3895:
3886:
3876:
3867:
3857:
3848:sodium selenite
3826:
3822:
3812:
3758:Rosmarinic acid
3722:
3530:Sulfonanilides:
3433:Oxyphenbutazone
2959:
2941:
2929:
2708:
2649:
2521:
2508:
2493:
2489:
2479:
2439:
2436:Prostaglandin E
2431:, epoprostenol)
2430:
2365:
2361:
2351:
2326:
2323:Prostaglandin F
2318:
2315:Prostaglandin D
2268:
2264:
2250:
2235:
2232:Prostaglandin F
2197:
2179:
2144:
2141:Prostaglandin E
2135:
2132:Prostaglandin E
2110:
2107:
2097:
2078:Ricinoleic acid
2067:
2064:Prostaglandin E
2058:
2055:Prostaglandin E
2050:
2047:Prostaglandin D
1995:
1992:
1982:
1952:
1949:Prostaglandin E
1943:
1940:Prostaglandin E
1918:
1915:
1905:
1865:
1862:Prostaglandin E
1856:
1853:Prostaglandin E
1811:
1808:
1794:
1790:
1776:
1707:
1704:Prostaglandin D
1687:
1684:
1674:
1645:
1642:Prostaglandin D
1630:
1627:
1613:
1609:
1590:
1582:
1571:
1541:
1536:
1529:
1520:
1500:
1480:
1472:
1457:
1449:
1431:
1423:
1408:
1388:
1380:
1372:
1364:
1356:
1339:
1331:
1323:
1304:
1296:
1288:
1280:
1272:
1250:
1240:
1233:
1208:
1204:
1196:
1188:
1180:
1165:
1135:
1131:
1123:
1115:
1098:
1094:
1086:
1071:
1041:
1037:
1029:
1003:
997:
982:
976:
965:
954:
936:
932:
910:
906:
872:
856:
851:
809:
804:
783:(10): 533–540.
769:
765:
734:
730:
685:
681:
658:
654:
615:
611:
598:
594:
571:
567:
538:
534:
497:
493:
454:
450:
411:
407:
400:
396:
386:
384:
382:
364:Asthma and COPD
356:
352:
348:
287:
274:
256:
249:
245:
241:
228:
206:
201:
195:
174:balance in the
165:vasoconstrictor
161:
153:
145:coupled to the
135:
120:
117:prostaglandin H
111:, converts the
86:
28:
27:Group of lipids
23:
22:
15:
12:
11:
5:
4130:
4120:
4119:
4102:
4101:
4099:
4098:
4091:
4084:
4080:
4077:
4076:
4074:
4073:
4069:
4065:
4061:
4057:
4052:
4050:Diacylglycerol
4047:
4042:
4037:
4028:
4026:
4022:
4021:
4018:
4017:
4015:
4014:
4009:
4004:
3999:
3994:
3989:
3984:
3979:
3974:
3969:
3964:
3959:
3954:
3949:
3944:
3939:
3933:
3931:
3920:
3919:
3914:
3912:
3903:
3897:
3896:
3891:
3889:
3878:
3877:
3872:
3870:
3859:
3858:
3856:
3855:
3837:
3831:
3829:
3820:
3814:
3813:
3811:
3810:
3805:
3800:
3795:
3790:
3785:
3780:
3775:
3770:
3765:
3760:
3755:
3750:
3745:
3740:
3735:
3730:
3725:
3720:
3716:
3711:
3706:
3701:
3696:
3691:
3686:
3681:
3676:
3671:
3666:
3661:
3656:
3644:
3639:
3634:
3629:
3624:
3619:
3614:
3609:
3604:
3599:
3594:
3589:
3584:
3572:
3567:
3562:
3557:
3552:
3547:
3535:
3523:
3518:
3506:
3494:
3489:
3477:
3472:
3467:
3462:
3457:
3452:
3447:
3438:Phenylbutazone
3435:
3430:
3425:
3420:
3408:
3403:
3398:
3393:
3388:
3383:
3378:
3373:
3361:
3356:
3351:
3346:
3341:
3336:
3331:
3326:
3321:
3316:
3311:
3306:
3301:
3296:
3291:
3286:
3281:
3276:
3271:
3266:
3261:
3256:
3251:
3246:
3241:
3236:
3231:
3219:
3214:
3209:
3204:
3199:
3194:
3189:
3184:
3179:
3174:
3169:
3164:
3159:
3154:
3149:
3144:
3139:
3134:
3129:
3124:
3119:
3114:
3109:
3104:
3099:
3094:
3089:
3084:
3079:
3074:
3069:
3057:
3052:
3047:
3042:
3037:
3032:
3027:
3022:
3017:
3012:
3007:
3002:
2997:
2992:
2987:
2982:
2977:
2968:
2966:
2949:
2935:
2934:
2931:
2930:
2928:
2927:
2922:
2917:
2912:
2907:
2902:
2897:
2892:
2887:
2882:
2877:
2872:
2867:
2862:
2857:
2852:
2847:
2842:
2837:
2832:
2827:
2822:
2817:
2812:
2807:
2802:
2797:
2792:
2787:
2782:
2777:
2772:
2767:
2762:
2757:
2752:
2747:
2742:
2737:
2732:
2727:
2722:
2716:
2714:
2710:
2709:
2707:
2706:
2701:
2696:
2691:
2686:
2681:
2676:
2671:
2666:
2661:
2656:
2651:
2647:
2643:
2638:
2633:
2628:
2623:
2618:
2613:
2608:
2603:
2598:
2593:
2588:
2583:
2578:
2573:
2568:
2563:
2558:
2553:
2548:
2543:
2534:
2533:
2528:
2523:
2519:
2515:
2510:
2506:
2498:
2496:
2487:
2481:
2480:
2478:
2477:
2468:
2467:
2462:
2457:
2452:
2447:
2442:
2437:
2433:
2428:
2424:
2419:
2414:
2412:Isocarbacyclin
2409:
2404:
2399:
2394:
2389:
2384:
2379:
2370:
2368:
2359:
2353:
2352:
2350:
2349:
2344:
2339:
2334:
2329:
2324:
2320:
2316:
2312:
2307:
2302:
2297:
2292:
2287:
2282:
2273:
2271:
2262:
2256:
2255:
2252:
2251:
2249:
2248:
2243:
2238:
2233:
2229:
2224:
2219:
2214:
2209:
2204:
2199:
2195:
2187:
2185:
2181:
2180:
2178:
2177:
2172:
2167:
2162:
2153:
2152:
2147:
2145:(dinoprostone)
2142:
2138:
2133:
2129:
2124:
2115:
2113:
2105:
2099:
2098:
2096:
2095:
2086:
2085:
2080:
2075:
2070:
2068:(dinoprostone)
2065:
2061:
2056:
2052:
2048:
2044:
2039:
2034:
2032:Isocarbacyclin
2029:
2024:
2019:
2014:
2009:
2000:
1998:
1990:
1984:
1983:
1981:
1980:
1975:
1970:
1961:
1960:
1955:
1953:(dinoprostone)
1950:
1946:
1941:
1937:
1932:
1923:
1921:
1913:
1907:
1906:
1904:
1903:
1898:
1893:
1888:
1883:
1874:
1873:
1868:
1866:(dinoprostone)
1863:
1859:
1854:
1850:
1845:
1840:
1835:
1830:
1825:
1816:
1814:
1806:
1797:
1788:
1782:
1781:
1778:
1777:
1775:
1774:
1769:
1764:
1759:
1754:
1749:
1744:
1739:
1734:
1729:
1724:
1719:
1710:
1709:
1705:
1701:
1692:
1690:
1682:
1676:
1675:
1673:
1672:
1667:
1662:
1653:
1652:
1647:
1643:
1635:
1633:
1625:
1616:
1607:
1598:
1584:
1583:
1570:
1569:
1562:
1555:
1547:
1538:
1537:
1535:
1534:
1533:
1532:
1527:
1523:
1522:(Dinoprostone)
1518:
1505:
1504:
1503:
1502:
1498:
1485:
1484:
1483:
1482:
1478:
1474:
1470:
1461:
1460:
1459:
1455:
1451:
1447:
1435:
1434:
1433:
1429:
1425:
1421:
1412:
1411:
1410:
1406:
1393:
1392:
1391:
1390:
1386:
1382:
1378:
1374:
1370:
1366:
1362:
1358:
1354:
1343:
1342:
1341:
1337:
1333:
1329:
1325:
1321:
1309:
1308:
1307:
1306:
1302:
1298:
1294:
1290:
1286:
1282:
1278:
1274:
1270:
1258:
1256:
1252:
1251:
1249:
1248:
1243:
1238:
1231:
1222:
1220:
1214:
1213:
1210:
1209:
1207:
1206:
1202:
1198:
1194:
1190:
1186:
1182:
1178:
1173:
1171:
1167:
1166:
1164:
1163:
1157:
1155:
1148:
1141:
1140:
1137:
1136:
1134:
1133:
1129:
1125:
1121:
1117:
1113:
1108:
1106:
1100:
1099:
1097:
1096:
1092:
1088:
1084:
1079:
1077:
1073:
1072:
1070:
1069:
1063:
1061:
1054:
1047:
1046:
1043:
1042:
1040:
1039:
1035:
1031:
1027:
1022:
1020:
1013:
1012:
1009:
1008:
1005:
1004:
1002:
1001:
995:
990:
988:
984:
983:
981:
980:
974:
969:
968:
963:
958:
957:
955:(Dinoprostone)
952:
947:
945:
938:
937:
935:
934:
930:
925:
923:
916:
912:
911:
909:
908:
904:
899:
897:
890:
887:Prostaglandins
880:
874:
873:
871:
870:
864:
862:
858:
857:
850:
849:
842:
835:
827:
821:
820:
808:
807:External links
805:
803:
802:
763:
728:
679:
652:
609:
592:
581:(7): 819–830.
565:
532:
491:
464:(1): 139–150.
448:
405:
394:
380:
349:
347:
344:
320:
319:
307:
289:
285:
272:
255:
252:
247:
243:
239:
227:
224:
204:
199:
194:
191:
160:
157:
151:
134:
131:
118:
85:
82:
67:thromboxane B2
63:thromboxane A2
45:Thromboxane B2
35:Thromboxane A2
26:
9:
6:
4:
3:
2:
4129:
4118:
4115:
4114:
4112:
4097:
4096:
4092:
4090:
4089:
4085:
4082:
4081:
4078:
4072:
4066:
4064:
4058:
4056:
4053:
4051:
4048:
4046:
4043:
4041:
4038:
4036:
4035:Linoleic acid
4033:
4030:
4029:
4027:
4023:
4013:
4010:
4008:
4005:
4003:
4000:
3998:
3995:
3993:
3990:
3988:
3985:
3983:
3980:
3978:
3975:
3973:
3970:
3968:
3965:
3963:
3960:
3958:
3955:
3953:
3950:
3948:
3945:
3943:
3940:
3938:
3935:
3934:
3932:
3927:
3921:
3917:
3913:
3908:
3898:
3894:
3890:
3885:
3879:
3875:
3871:
3866:
3860:
3853:
3849:
3845:
3841:
3838:
3836:
3833:
3832:
3830:
3825:
3815:
3809:
3806:
3804:
3801:
3799:
3796:
3794:
3791:
3789:
3786:
3784:
3781:
3779:
3776:
3774:
3771:
3769:
3766:
3764:
3761:
3759:
3756:
3754:
3751:
3749:
3746:
3744:
3741:
3739:
3736:
3734:
3731:
3729:
3726:
3724:
3717:
3715:
3712:
3710:
3707:
3705:
3702:
3700:
3697:
3695:
3692:
3690:
3687:
3685:
3682:
3680:
3677:
3675:
3672:
3670:
3667:
3665:
3662:
3660:
3657:
3655:
3652:
3648:
3645:
3643:
3640:
3638:
3635:
3633:
3630:
3628:
3625:
3623:
3620:
3618:
3615:
3613:
3610:
3608:
3605:
3603:
3600:
3598:
3595:
3593:
3590:
3588:
3585:
3583:
3580:
3576:
3573:
3571:
3568:
3566:
3563:
3561:
3558:
3556:
3553:
3551:
3548:
3546:
3543:
3539:
3536:
3534:
3531:
3527:
3524:
3522:
3519:
3517:
3514:
3510:
3507:
3505:
3504:Fluproquazone
3502:
3501:Quinazolines:
3498:
3495:
3493:
3490:
3488:
3485:
3481:
3478:
3476:
3473:
3471:
3468:
3466:
3463:
3461:
3458:
3456:
3453:
3451:
3448:
3446:
3443:
3439:
3436:
3434:
3431:
3429:
3426:
3424:
3421:
3419:
3416:
3412:
3409:
3407:
3404:
3402:
3399:
3397:
3394:
3392:
3389:
3387:
3384:
3382:
3379:
3377:
3374:
3372:
3369:
3365:
3362:
3360:
3357:
3355:
3352:
3350:
3347:
3345:
3342:
3340:
3337:
3335:
3332:
3330:
3327:
3325:
3322:
3320:
3317:
3315:
3312:
3310:
3307:
3305:
3302:
3300:
3297:
3295:
3292:
3290:
3287:
3285:
3282:
3280:
3279:Flunoxaprofen
3277:
3275:
3272:
3270:
3267:
3265:
3264:Dexketoprofen
3262:
3260:
3259:Dexindoprofen
3257:
3255:
3252:
3250:
3247:
3245:
3242:
3240:
3237:
3235:
3232:
3230:
3227:
3223:
3220:
3218:
3215:
3213:
3210:
3208:
3205:
3203:
3200:
3198:
3197:Proglumetacin
3195:
3193:
3190:
3188:
3185:
3183:
3180:
3178:
3175:
3173:
3170:
3168:
3165:
3163:
3160:
3158:
3155:
3153:
3150:
3148:
3145:
3143:
3140:
3138:
3135:
3133:
3130:
3128:
3127:Difenpiramide
3125:
3123:
3120:
3118:
3115:
3113:
3110:
3108:
3105:
3103:
3100:
3098:
3095:
3093:
3090:
3088:
3085:
3083:
3080:
3078:
3075:
3073:
3070:
3068:
3065:
3064:Acetic acids:
3061:
3058:
3056:
3053:
3051:
3048:
3046:
3043:
3041:
3038:
3036:
3033:
3031:
3028:
3026:
3023:
3021:
3018:
3016:
3013:
3011:
3008:
3006:
3003:
3001:
2998:
2996:
2993:
2991:
2988:
2986:
2983:
2981:
2978:
2976:
2973:
2970:
2969:
2967:
2965:
2953:
2950:
2946:
2940:
2936:
2926:
2923:
2921:
2918:
2916:
2913:
2911:
2908:
2906:
2903:
2901:
2898:
2896:
2893:
2891:
2888:
2886:
2883:
2881:
2878:
2876:
2873:
2871:
2868:
2866:
2863:
2861:
2858:
2856:
2853:
2851:
2848:
2846:
2843:
2841:
2838:
2836:
2833:
2831:
2828:
2826:
2823:
2821:
2818:
2816:
2813:
2811:
2808:
2806:
2803:
2801:
2798:
2796:
2795:Fenprostalene
2793:
2791:
2788:
2786:
2783:
2781:
2778:
2776:
2773:
2771:
2768:
2766:
2763:
2761:
2758:
2756:
2753:
2751:
2748:
2746:
2745:Delprostenate
2743:
2741:
2738:
2736:
2733:
2731:
2728:
2726:
2723:
2721:
2718:
2717:
2715:
2711:
2705:
2702:
2700:
2697:
2695:
2692:
2690:
2687:
2685:
2682:
2680:
2677:
2675:
2672:
2670:
2667:
2665:
2662:
2660:
2657:
2655:
2652:
2650:
2644:
2642:
2639:
2637:
2634:
2632:
2629:
2627:
2624:
2622:
2619:
2617:
2614:
2612:
2609:
2607:
2604:
2602:
2599:
2597:
2594:
2592:
2589:
2587:
2584:
2582:
2579:
2577:
2574:
2572:
2569:
2567:
2564:
2562:
2559:
2557:
2554:
2552:
2549:
2547:
2544:
2542:
2539:
2536:
2535:
2532:
2529:
2527:
2524:
2522:
2518:Thromboxane A
2516:
2514:
2511:
2509:
2503:
2500:
2499:
2497:
2492:
2482:
2476:
2473:
2470:
2469:
2466:
2463:
2461:
2458:
2456:
2453:
2451:
2448:
2446:
2443:
2441:
2440:(alprostadil)
2434:
2432:
2425:
2423:
2420:
2418:
2415:
2413:
2410:
2408:
2405:
2403:
2400:
2398:
2395:
2393:
2390:
2388:
2385:
2383:
2380:
2378:
2375:
2372:
2371:
2369:
2364:
2354:
2348:
2345:
2343:
2340:
2338:
2335:
2333:
2330:
2328:
2321:
2319:
2313:
2311:
2308:
2306:
2303:
2301:
2298:
2296:
2293:
2291:
2288:
2286:
2283:
2281:
2278:
2275:
2274:
2272:
2267:
2257:
2247:
2244:
2242:
2239:
2237:
2230:
2228:
2225:
2223:
2220:
2218:
2215:
2213:
2210:
2208:
2205:
2203:
2200:
2198:
2192:
2189:
2188:
2186:
2182:
2176:
2173:
2171:
2168:
2166:
2163:
2161:
2158:
2155:
2154:
2151:
2148:
2146:
2139:
2137:
2136:(alprostadil)
2130:
2128:
2125:
2123:
2120:
2117:
2116:
2114:
2109:
2100:
2094:
2091:
2088:
2087:
2084:
2081:
2079:
2076:
2074:
2071:
2069:
2062:
2060:
2059:(alprostadil)
2053:
2051:
2045:
2043:
2040:
2038:
2035:
2033:
2030:
2028:
2025:
2023:
2020:
2018:
2015:
2013:
2010:
2008:
2005:
2002:
2001:
1999:
1994:
1985:
1979:
1976:
1974:
1971:
1969:
1966:
1963:
1962:
1959:
1956:
1954:
1947:
1945:
1944:(alprostadil)
1938:
1936:
1933:
1931:
1928:
1925:
1924:
1922:
1917:
1908:
1902:
1899:
1897:
1894:
1892:
1889:
1887:
1884:
1882:
1879:
1876:
1875:
1872:
1869:
1867:
1860:
1858:
1857:(alprostadil)
1851:
1849:
1846:
1844:
1841:
1839:
1836:
1834:
1831:
1829:
1826:
1824:
1821:
1818:
1817:
1815:
1810:
1801:
1798:
1793:
1783:
1773:
1770:
1768:
1765:
1763:
1760:
1758:
1755:
1753:
1750:
1748:
1745:
1743:
1740:
1738:
1735:
1733:
1730:
1728:
1725:
1723:
1720:
1718:
1715:
1712:
1711:
1708:
1702:
1700:
1697:
1694:
1693:
1691:
1686:
1677:
1671:
1668:
1666:
1663:
1661:
1658:
1655:
1654:
1651:
1648:
1646:
1640:
1637:
1636:
1634:
1629:
1620:
1617:
1612:
1602:
1599:
1595:
1589:
1585:
1581:
1578:
1575:
1568:
1563:
1561:
1556:
1554:
1549:
1548:
1545:
1530:
1524:
1521:
1515:
1514:
1513:
1511:
1507:
1506:
1501:
1495:
1494:
1493:
1491:
1487:
1486:
1481:
1475:
1473:
1467:
1466:
1465:
1462:
1458:
1452:
1450:
1444:
1443:
1442:
1440:
1436:
1432:
1426:
1424:
1418:
1417:
1416:
1413:
1409:
1403:
1402:
1401:
1399:
1395:
1394:
1389:
1383:
1381:
1375:
1373:
1367:
1365:
1359:
1357:
1351:
1350:
1349:
1348:
1344:
1340:
1334:
1332:
1326:
1324:
1318:
1317:
1316:
1315:
1311:
1310:
1305:
1299:
1297:
1291:
1289:
1283:
1281:
1275:
1273:
1267:
1266:
1265:
1264:
1260:
1259:
1257:
1253:
1247:
1244:
1241:
1234:
1227:
1224:
1223:
1221:
1219:
1215:
1205:
1199:
1197:
1191:
1189:
1183:
1181:
1175:
1174:
1172:
1168:
1162:
1159:
1158:
1156:
1152:
1149:
1146:
1142:
1132:
1126:
1124:
1118:
1116:
1110:
1109:
1107:
1105:
1101:
1095:
1089:
1087:
1081:
1080:
1078:
1074:
1068:
1065:
1064:
1062:
1058:
1055:
1052:
1048:
1038:
1032:
1030:
1024:
1023:
1021:
1018:
1014:
999:
992:
991:
989:
985:
978:
971:
970:
967:
966:(Alprostadil)
960:
959:
956:
949:
948:
946:
943:
939:
933:
927:
926:
924:
920:
917:
913:
907:
901:
900:
898:
894:
891:
888:
884:
881:
879:
875:
869:
866:
865:
863:
859:
855:
848:
843:
841:
836:
834:
829:
828:
825:
818:
814:
811:
810:
798:
794:
790:
786:
782:
778:
774:
767:
759:
755:
751:
747:
743:
739:
732:
724:
720:
715:
710:
706:
702:
698:
694:
690:
683:
675:
671:
668:(8): 973–80.
667:
663:
656:
648:
644:
640:
636:
632:
628:
624:
620:
613:
607:
604:
600:
596:
588:
584:
580:
576:
569:
560:
555:
551:
547:
543:
536:
528:
524:
519:
514:
510:
506:
502:
495:
487:
483:
479:
475:
471:
467:
463:
459:
452:
444:
440:
436:
432:
428:
424:
421:(5): 408–16.
420:
416:
409:
403:
398:
383:
381:9780123740014
377:
373:
369:
365:
361:
354:
350:
343:
341:
337:
335:
331:
329:
325:
317:
312:
308:
305:
301:
297:
293:
290:
283:
279:
275:
271:thromboxane A
268:
264:
263:
262:
259:
251:
237:
233:
223:
221:
217:
213:
208:
202:
198:Thromboxane A
190:
188:
183:
181:
177:
173:
168:
166:
156:
154:
148:
144:
140:
130:
128:
123:
121:
114:
110:
106:
98:
90:
81:
79:
74:
72:
68:
64:
60:
56:
52:
46:
42:
36:
32:
19:
4093:
4086:
4031:
3650:
3578:
3575:Propacetamol
3565:Parapropamol
3541:
3529:
3512:
3500:
3492:Floctafenine
3483:
3441:
3418:Azapropazone
3415:Pyrazolones:
3414:
3367:
3349:Tarenflurbil
3284:Flurbiprofen
3254:Dexibuprofen
3234:Benoxaprofen
3229:Alminoprofen
3225:
3152:Glucametacin
3063:
3040:Salicylamide
3030:Salacetamide
2971:
2920:Trimoprostil
2915:Tiprostanide
2900:Spiriprostil
2835:Naxaprostene
2785:Esuberaprost
2740:Cobiprostone
2538:Antagonists:
2537:
2501:
2472:Antagonists:
2471:
2465:Treprostinil
2373:
2305:Fluprostenol
2295:Cloprostenol
2276:
2190:
2157:Antagonists:
2156:
2122:Lubiprostone
2118:
2090:Antagonists:
2089:
2003:
1965:Antagonists:
1964:
1958:Treprostinil
1926:
1878:Antagonists:
1877:
1843:Lubiprostone
1819:
1714:Antagonists:
1713:
1695:
1657:Antagonists:
1656:
1650:Treprostinil
1638:
1512:stimulation:
1508:
1492:stimulation:
1488:
1463:
1437:
1414:
1396:
1347:vasodilation
1345:
1312:
1261:
1051:Leukotrienes
1017:Thromboxanes
1016:
813:Thromboxanes
780:
776:
766:
744:(1): 77–83.
741:
737:
731:
696:
692:
682:
665:
661:
655:
622:
618:
612:
602:
595:
578:
574:
568:
552:(1): 38–44.
549:
545:
535:
511:(8): 801–7.
508:
504:
494:
461:
457:
451:
418:
415:Eur Surg Res
414:
408:
397:
385:. Retrieved
363:
353:
338:
332:
326:, including
321:
304:Dipyridamole
260:
257:
229:
209:
196:
184:
180:prostacyclin
169:
162:
136:
125:People with
124:
103:
75:
50:
49:
18:Thromboxanes
4117:Eicosanoids
4032:Precursors:
3972:Nicogrelate
3952:Furegrelate
3893:Bimatoprost
3803:Trifenagrel
3793:Tiflamizole
3763:Rutecarpine
3748:Resveratrol
3689:Glimepiride
3654:Anitrazafen
3632:Robenacoxib
3612:Lumiracoxib
3545:Acetanilide
3487:Antrafenine
3445:Ampiroxicam
3339:Pranoprofen
3324:Naproxcinod
3217:Zidometacin
3142:Fenclofenac
3067:Aceclofenac
3005:Ethenzamide
3000:Dipyrocetyl
2895:Rosaprostol
2875:Posaraprost
2860:Penprostene
2850:Ornoprostil
2830:Mexiprostil
2825:Meteneprost
2780:Eptaloprost
2755:Dimoxaprost
2720:Arbaprostil
2674:Seratrodast
2566:BMS-180,291
2397:Carbacyclin
2347:Unoprostone
2327:(dinoprost)
2310:Latanoprost
2285:Bimatoprost
2280:Alfaprostol
2236:(dinoprost)
2175:ONO-AE3-208
2127:Misoprostol
2083:Sulprostone
2073:Remiprostol
2042:Misoprostol
2037:Latanoprost
2012:Carbacyclin
1973:PF-04418948
1935:Misoprostol
1871:Sulprostone
1848:Misoprostol
1838:Latanoprost
1772:Vidupiprant
1762:Timapiprant
1757:Setipiprant
1732:Fevipiprant
1699:Indometacin
1670:Vidupiprant
1665:Laropiprant
1531:(Dinoprost)
1255:By function
1246:Virodhamine
977:(Dinoprost)
878:Prostanoids
854:Eicosanoids
366:: 655–662.
212:GP IIb/IIIa
172:homeostatic
115:derivative
59:eicosanoids
51:Thromboxane
4002:Samixogrel
3997:Rolafagrel
3982:Picotamide
3962:Midazogrel
3937:Camonagrel
3798:Timegadine
3743:Pamicogrel
3714:Licofelone
3694:Hyperforin
3659:Clobuzarit
3647:Valdecoxib
3642:Tilmacoxib
3627:Polmacoxib
3602:Etoricoxib
3570:Phenacetin
3538:Nimesulide
3516:Clonixeril
3509:Proquazone
3465:Lornoxicam
3364:Vedaprofen
3314:Miroprofen
3309:Loxoprofen
3304:Ketoprofen
3299:Indoprofen
3274:Fenoprofen
3187:Oxametacin
3182:Nabumetone
3122:Diclofenac
3117:Clometacin
3112:Cinmetacin
3107:Bumadizone
3087:Alclofenac
3072:Acemetacin
3010:Guacetisal
2995:Diflunisal
2945:inhibitors
2910:Tilsuprost
2890:Rivenprost
2885:Rioprostil
2880:Prostalene
2865:Pimilprost
2855:Oxoprostol
2845:Nocloprost
2820:Luprostiol
2810:Lanproston
2805:Froxiprost
2800:Flunoprost
2790:Etiproston
2775:Enisoprost
2770:Eganoprost
2730:Ciprostene
2699:Terutroban
2689:Sulotroban
2669:Samixogrel
2654:Ramatroban
2641:Picotamide
2626:Mipitroban
2621:Linotroban
2606:Imitrodast
2596:ICI-192605
2591:ICI-185282
2576:Domitroban
2556:Argatroban
2455:Taprostene
2377:ACT-333679
2342:Travoprost
2337:Tafluprost
2332:Sulotroban
2290:Carboprost
2246:Taprenepag
2227:Omidenepag
2222:Nocloprost
2212:Evatanepag
2207:Carboprost
2160:Grapiprant
1752:Ramatroban
1660:Asapiprant
1580:modulators
1574:Prostanoid
1439:leukocytes
1218:Nonclassic
505:Arch. Surg
458:Hepatology
387:20 January
346:References
334:Picotamide
328:terutroban
309:High-dose
216:fibrinogen
84:Production
78:thrombosis
4007:Terbogrel
3987:Pirmagrel
3947:Dazoxiben
3942:Dazmegrel
3835:Retinoids
3753:Romazarit
3699:Itazigrel
3684:FR-122047
3679:Flumizole
3637:Rofecoxib
3622:Parecoxib
3617:Mavacoxib
3607:Firocoxib
3597:Deracoxib
3592:Cimicoxib
3587:Celecoxib
3582:Apricoxib
3533:Flosulide
3497:Glafenine
3480:Tenoxicam
3475:Piroxicam
3470:Meloxicam
3354:Tepoxalin
3334:Pirprofen
3329:Oxaprozin
3294:Ibuproxam
3289:Ibuprofen
3249:Carprofen
3244:Butibufen
3222:Zomepirac
3192:Oxindanac
3177:Mofezolac
3172:Lonazolac
3167:Ketorolac
3147:Fentiazac
3102:Bufexamac
3097:Bromfenac
3077:Aclofenac
3060:Triflusal
3050:Salsalate
2975:Aloxiprin
2925:Viprostol
2870:Piriprost
2840:Nileprost
2815:Limaprost
2765:Ecraprost
2760:Doxaprost
2750:Deprostil
2735:Clinprost
2694:Terbogrel
2684:SQ-29,548
2679:SQ-28,668
2636:ONO-11120
2601:Ifetroban
2571:Daltroban
2561:Bay U3405
2531:Vapiprost
2502:Agonists:
2475:RO1138452
2450:Selexipag
2445:Ralinepag
2402:Cicaprost
2392:BMY-45778
2387:Beraprost
2374:Agonists:
2300:Enprostil
2277:Agonists:
2241:Simenepag
2217:Gemeprost
2191:Agonists:
2165:GW-627368
2119:Agonists:
2022:Enprostil
2017:Cicaprost
2007:Beraprost
2004:Agonists:
1930:Butaprost
1927:Agonists:
1828:Enprostil
1823:Beraprost
1820:Agonists:
1727:Bay U3405
1696:Agonists:
1639:Agonists:
1577:signaling
1398:platelets
1154:Precursor
1060:Precursor
896:Precursor
861:Precursor
789:0034-1193
300:Ifetroban
278:platelets
226:Pathology
170:It is in
159:Functions
147:G protein
133:Mechanism
109:platelets
57:known as
4111:Category
4083:See also
3992:Ridogrel
3967:Nafagrel
3957:Isbogrel
3840:Selenium
3808:Tropesin
3783:SC-58125
3768:Satigrel
3733:NCX-4040
3709:L-670596
3704:L-655240
3664:Curcumin
3526:Flunixin
3521:Clonixin
3460:Isoxicam
3455:Enolicam
3450:Droxicam
3428:Isopyrin
3423:Dipyrone
3344:Suprofen
3319:Naproxen
3269:Fenbufen
3212:Tolmetin
3202:Sulindac
3137:Felbinac
3132:Etodolac
3092:Bendazac
2905:Tiaprost
2725:Ataprost
2713:Unsorted
2659:Ridogrel
2631:ONO-3708
2616:L-670596
2611:L-655240
2586:GR-32191
2202:Aganepag
2184:Unsorted
2170:L-161982
2150:TCS-2510
2093:L-798106
1978:TG 4-155
1901:SC-51322
1896:SC-51089
1891:SC-19220
1886:ONO-8130
1722:AZD-1981
1717:ADC-3680
1588:Receptor
1441:: induce
1400:: induce
1226:Lipoxins
723:23726390
674:10901709
647:14177039
587:20503171
527:16103291
486:27252438
478:14752832
443:40932766
435:12928598
340:Ridogrel
311:naproxen
4012:U63557A
3977:Ozagrel
3788:Tenidap
3728:NCX-466
3674:FK-3311
3669:DuP-697
3555:Bucetin
3082:Amfenac
3035:Salicin
2704:TRA-418
2551:AA-2414
2541:12-HETE
2526:U-46619
2460:TRA-418
2417:MRE-269
1968:AH-6809
1881:AH-6809
1767:TM30089
1747:QAV-680
1742:MK-7246
1737:MK-1029
1594:ligands
1464:inhibit
1415:inhibit
1076:Initial
797:1759039
758:9754941
714:3778977
639:1412574
267:aspirin
246:and PGI
4025:Others
3874:HQL-79
3778:SC-560
3773:SC-236
3738:NS-398
2939:Enzyme
2581:EP-045
2546:13-APA
2486:TP (TX
2422:NS-304
2382:AFP-07
1228:(LX) (
1170:Eoxins
1145:Eoxins
915:Active
819:(MeSH)
795:
787:
756:
721:
711:
693:Lancet
672:
645:
637:
619:Stroke
585:
525:
484:
476:
441:
433:
378:
127:asthma
55:lipids
2664:S-145
2513:I-BOP
2358:IP (I
2261:FP (F
1787:EP (E
1606:DP (D
1510:labor
1490:fever
1104:SRS-A
643:S2CID
482:S2CID
439:S2CID
316:COX-1
178:with
71:ether
3925:TXAS
3883:PGFS
3864:PGES
2962:PTGS
1147:(EX)
1053:(LT)
1019:(TX)
889:(PG)
793:PMID
785:ISSN
754:PMID
719:PMID
670:PMID
635:PMID
583:PMID
523:PMID
474:PMID
431:PMID
389:2023
376:ISBN
220:clot
203:(TXA
65:and
3902:PGI
3819:PGD
2957:COX
1526:PGF
1517:PGE
1497:PGE
1477:PGE
1469:PGD
1454:LTB
1446:TXA
1428:PGI
1420:PGD
1405:TXA
1385:LTE
1377:LTD
1369:LTC
1361:PGI
1353:PGE
1336:TXB
1328:TXA
1320:PGF
1301:LTE
1293:LTD
1285:LTC
1277:TXA
1269:PGD
922:D/J
746:doi
742:355
709:PMC
701:doi
697:382
627:doi
554:doi
513:doi
509:140
466:doi
423:doi
368:doi
276:in
80:).
4113::
3850:,
3846:,
3649:;
3577:;
3540:;
3528:;
3511:;
3499:;
3482:;
3440:;
3413:;
3366:;
3224:;
3062:;
2488:A2
2325:2α
2263:2α
2234:2α
2104:EP
1989:EP
1912:EP
1805:EP
1681:DP
1624:DP
1528:2α
1322:2α
1235:,
975:2α
944:/F
791:.
781:82
779:.
775:.
752:.
740:.
717:.
707:.
695:.
691:.
666:28
664:.
641:.
633:.
623:23
621:.
579:25
577:.
548:.
544:.
521:.
507:.
503:.
480:.
472:.
462:39
460:.
437:.
429:.
419:35
417:.
374:.
362:.
330:.
234:.
222:.
155:.
141:,
4070:2
4062:2
3906:S
3904:2
3854:)
3842:(
3823:S
3821:2
3723:)
3721:2
2964:)
2960:(
2947:)
2943:(
2648:2
2520:2
2507:2
2490:)
2438:1
2429:2
2362:)
2360:2
2317:2
2265:)
2196:2
2143:2
2134:1
2106:4
2066:2
2057:1
2049:2
1991:3
1951:2
1942:1
1914:2
1864:2
1855:1
1807:1
1791:)
1789:2
1706:2
1683:2
1644:2
1626:1
1610:)
1608:2
1596:)
1592:(
1566:e
1559:t
1552:v
1519:2
1499:2
1479:2
1471:2
1456:4
1448:2
1430:2
1422:2
1407:2
1387:4
1379:4
1371:4
1363:2
1355:2
1338:2
1330:2
1303:4
1295:4
1287:4
1279:2
1271:2
1242:)
1239:4
1237:B
1232:4
1230:A
1203:4
1201:E
1195:4
1193:D
1187:4
1185:C
1179:4
1177:A
1130:4
1128:E
1122:4
1120:D
1114:4
1112:C
1093:4
1091:B
1085:4
1083:A
1036:2
1034:B
1028:2
1026:A
1000::
996:2
994:I
987:I
979::
973:F
964:1
962:E
953:2
951:E
942:E
931:2
929:D
905:2
903:H
846:e
839:t
832:v
799:.
760:.
748::
725:.
703::
676:.
649:.
629::
589:.
562:.
556::
550:1
529:.
515::
488:.
468::
445:.
425::
391:.
370::
286:2
273:2
248:3
244:2
240:3
205:2
200:2
152:q
150:G
119:2
20:)
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
