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Clinical studies have researched the properties of tertiary dentin formation, including anatomy in both humans and animal models, usually from an oral health perspective. Genetic changes in animal models can increase tertiary dentin production. This suggests certain species may have evolved to
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Wear on the surface of a tooth can lead to the exposure of the underlying dentin. When wear is severe tertiary dentin may form to help protect the pulp chamber. Frequency of tertiary dentin in different species of primate suggests teeth 'heal' at different rates in different species.
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and infection. This form of dentin can be easily distinguished on the surface of a tooth, and is much darker in appearance compared to primary dentin. Tertiary dentin will often not be visible on the surface of a tooth, but because it is more dense it can be viewed on a
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Zuo, Jing; Zhen, Jiaxiu; Wang, Fei; Li, Yueheng; Zhou, Zhi (January 2018). "Effect of Low-Intensity Pulsed
Ultrasound on the Expression of Calcium Ion Transport-Related Proteins during Tertiary Dentin Formation".
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produce tertiary dentin in response to dietary changes. For example, gorillas may have evolved high rates of tertiary dentin as protection against severe wear, since they consume a lot of tough vegetation.
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Tertiary dentin on the surface of a gorilla tooth. The darker area indicated by the white arrow is tertiary dentin and has formed as a response to tooth wear.
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have a much lower rate of tertiary dentin formation, with around 15% of teeth that have dentin exposed through wear showing tertiary dentin formation.
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Moggi-Cecchi, Jacopo; Menter, Colin; Dori, Irene; Irish, Joel D.; Riga, Alessandro; Towle, Ian (12 March 2019).
60:. Tertiary dentin is therefore a mechanism for a tooth to ‘heal’, with new material formation protecting the
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have a high rate of tertiary dentin formation, with over 90% of worn teeth showing tertiary dentin.
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Neves, V.C.M.; Sharpe, P.T. (29 November 2017). "Regulation of
Reactionary Dentine Formation".
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and ultimately therefore protecting the tooth and individual against
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193:"Root caries on a Paranthropus robustus third molar from Drimolen"
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Dentin which forms in a tooth as a reaction to trauma
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48:as a reaction to stimulation, including
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261:Towle, Ian (20 March 2019).
125:Towle, Ian (20 March 2019).
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299:Journal of Dental Research
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168:10.1017/cbo9780511614477
158:Hillson, Simon (2005).
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38:dentin
323:S2CID
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