633:
610:
140:
1214:
1161:
25:
131:
3001:
1275:
This accumulation results in therapeutic levels of terbinafine even after 80 days following one week treatment of 250 mg/day. Different dosing schedules have been proposed such as 500 mg/day for one week or 250 mg/day for two weeks each followed by a drug-free period of two or three
1376:
Lamisil in
Argentina, Australia, Bangladesh, Belgium, Brazil, Canada, Chile, Colombia, Croatia, Egypt, the Czech Republic, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Iceland, Ireland, Israel, Mexico, the Netherlands, New Zealand, Norway, Pakistan, Peru, the Philippines, Romania,
1249:- there is enough difference in this enzyme that terbinafine preferentially binds fungal squalene epoxidase, making it selective for inhibiting ergosterol production in fungi without significantly affecting cholesterol production in mammals. This is thought to fatally disrupt the fungal
1393:
In India, terbinafine hydrochloride is available in topical form under the brand names
Triabin by Medley Pharmaceuticals, Sebifin (Sun Pharma), Zimig (GSK Pharma) and mycoCeaze (Progreś Laboratories). MycoVa, developed by
2207:
1074:), often involving a metallic taste sensation and dry mouth, visual disturbances including blurred vision, green vision and double vision. In extremely rare cases, the loss or impairment of taste is permanent
1387:
As a generic oral medication, it is sold as
Sebifin, Tinasil, Terbisil, Terbicor, and Tamsil in Australia, whilst the generic topical medication is sold there as SolvEasyTinea and Tamsil.
1147:
revealed the MTHFR C677T mutation. It was noted that
Lamisil interferes with the methylation cycle and that this can cause side effects in individuals with the MTHFR C677T mutation.
297:
1875:
1338:
has approved the first generic versions of prescription
Lamisil (terbinafine hydrochloride) tablets. The remaining patent or exclusivity for Lamisil expired on June 30, 2007.
937:
and the often extended durations involved in antifungal treatment (longer than two months). A comprehensive list of adverse events associated with terbinafine use includes:
2199:
3041:
1831:
242:
1276:
weeks, totaling 3 months of treatment including the drug-free periods. Such intermittent dosing schedules appear to be as effective as continuous regimens.
1852:
2041:
1984:
751:
693:
1390:
It is also available as a generic medication in the United States, the United
Kingdom, Belgium, Switzerland, Brazil, Mexico, Canada and France.
162:
1451:
707:
2104:
1686:
818:
is not typically recommended. The cream and ointment may result in itchiness but are generally well tolerated. Terbinafine is in the
1867:
2185:
1359:
In the United States the price in 1999 was $ 547 for a 12-week course; this fell to $ 10 by 2015, after the patent had expired.
2156:
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2955:
2239:
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or applied to the skin as a cream or ointment. The cream and ointment should not be used for fungal nail infections.
727:
108:
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to which topically applied treatments are unable to penetrate in sufficient amounts. The tablets may, rarely, cause
2972:
68:
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282:
194:
1377:
Russia, Slovakia, Slovenia, South Africa, Sweden, Thailand, the United
Kingdom, the United States, and Venezuela
2722:
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735:
InChI=1S/C21H25N/c1-21(2,3)15-8-5-9-16-22(4)17-19-13-10-12-18-11-6-7-14-20(18)19/h5-7,9-14H,16-17H2,1-4H3/b9-5+
46:
2033:
3051:
1602:
Yan J, Wang X, Chen S (August 2014). "Systematic review of severe acute liver injury caused by terbinafine".
75:
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1178:
1094:
628:
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589:
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3031:
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837:. In 2021, it was the 245th most commonly prescribed medication in the United States, with more than 1
578:
2790:
2760:
2232:
1550:
1413:) and Tafine (Deurali Janta Pharmaceuticals Pvt Ltd.) Turbo (Apex Pharmaceuticals Pvt Ltd) in Nepal.
2655:
1792:"Subacute cutaneous lupus erythematosus induced or exacerbated by terbinafine: a report of 5 cases"
605:
2960:
2890:
1447:
1171:
224:
172:
152:
35:
1985:"The efficacy and safety of pulse vs. continuous therapy for dermatophyte toenail onychomycosis"
1334:
Terbinafine first became available in Europe in 1991 and in the United States in 1996. The U.S.
2927:
2574:
1928:
Persistent loss of taste associated with terbinafine would however appear to be extremely rare.
930:
803:
363:
235:
1380:
Corbinal and
Terbisil in Turkey, Pakistan, Undofen in Poland. Another alternate is Terbistad (
2096:
1670:
1346:
802:
Common side effects when taken by mouth include nausea, diarrhea, headache, cough, rash, and
776:
772:
558:
498:
1757:"Clinical inquiries. What is the most effective treatment for tinea pedis (athlete's foot)?"
3021:
2225:
907:
518:
432:
385:
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3046:
2717:
2533:
1395:
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1035:
918:
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2177:
632:
609:
2880:
2850:
2845:
2015:
1965:
1627:
1524:
1507:
1381:
1373:
Terbinafine is sold in India as
Terboderm by Omega Pharma and Tyza (Abbott Healthcare).
1226:
867:
811:
933:
have been reported with oral terbinafine hydrochloride, possibly due to its extensive
2741:
2078:
2019:
2007:
1969:
1957:
1919:
1846:
1813:
1768:
1676:
1619:
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1100:
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should first discuss possible risks with their doctor before initiation of therapy.
458:
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2835:
2073:
2068:
2056:
1999:
1949:
1909:
1803:
1730:
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1558:
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1019:
1003:
988:, light-headedness, decreased concentration levels, paraesthesia (pins and needles)
894:
859:
645:
345:
265:
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139:
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1476:
1341:
On
September 28, 2007, the FDA stated that terbinafine is now approved for use by
1213:
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2467:
2457:
1953:
1293:
1144:
1023:
934:
822:
family of medications. It works by decreasing the ability of fungi to synthesize
373:
353:
1808:
1791:
2966:
2897:
2840:
2810:
2795:
2563:
2452:
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807:
2057:"Cost-effectiveness of Confirmatory Testing Before Treatment of Onychomycosis"
1756:
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1139:
variant) had developed an adverse reaction to Lamisil (headache, fatigue, and
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2696:
2670:
2477:
2429:
2395:
2350:
2320:
1403:
1353:
1285:
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2495:
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2380:
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2355:
2340:
2330:
2315:
2256:
2252:
2082:
2011:
1961:
1923:
1914:
1897:
1817:
1772:
1672:
The Evolution of Drug Discovery: From Traditional Medicines to Modern Drugs
1623:
1555:
World Health Organization model list of essential medicines: 21st list 2019
1533:
1007:
992:
946:
260:
250:
1983:
Gupta AK, Stec N, Bamimore MA, Foley KA, Shear NH, Piguet V (March 2020).
1349:
2941:
2902:
2860:
2830:
2731:
2675:
2611:
2447:
2439:
2434:
2405:
2400:
2390:
2385:
2360:
2335:
1834:. Doublecheckmd.com. 2010-06-16. Archived from the original on 2013-09-21
1477:"Lamisil 1% w/w Cream – Summary of Product Characteristics (SPC) – (eMC)"
1246:
1242:
1104:
1027:
1015:
966:
954:
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180:
1645:
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478:
2931:
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2870:
2855:
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2690:
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2538:
2375:
2325:
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1234:
1222:
1185: in this section. Unsourced material may be challenged and removed.
1124:
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1011:
970:
898:
species. Fungal nail infections are located deep under the nail in the
854:
823:
669:
489:
2200:"PI and CMI Trade Names and Active Ingredients containing Terbinafine"
2003:
2917:
2865:
2594:
2553:
2519:
2345:
2301:
1312:
1140:
1086:
1071:
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1342:
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942:
879:
784:
538:
469:
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2936:
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1940:
Trachtman JN, Pagano V (December 2015). "Antifolates and MTHFR".
1323:
1297:
1120:
1063:
1057:
1045:
985:
899:
1116:
1078:
950:
569:
1992:
Journal of the European Academy of Dermatology and Venereology
130:
2285:
1399:
1136:
1132:
1082:
1053:
683:
549:
378:
2054:
1898:"Persistent impairment of taste associated with terbinafine"
1416:
The topical form is sold as Lamisil AT in the United States.
594:
1261:
906:, so patients are warned of this and may be monitored with
850:
529:
1868:"Australian regulators issue warning on Novartis' Lamisil"
1247:
as fungi and animals diverged around 1.1 billion years ago
892:, a fungal nail infection, typically by a dermatophyte or
2149:"Mercury Drug – The Leading Drugstore in the Philippines"
2055:
Mikailov A, Cohen J, Joyce C, Mostaghimi A (March 2016).
1549:
910:. Alternatives to oral administration have been studied.
1789:
1567:. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
1288:
is a white crystalline powder that is freely soluble in
1790:
Callen JP, Hughes AP, Kulp-Shorten C (September 2001).
835:
World Health Organization's List of Essential Medicines
1982:
1895:
1889:
2989:
1450:. The American Society of Health-System Pharmacists.
814:. Liver injury is, however, unusual. Oral use during
1131:
In 2015, physicians reported that a patient with an
991:
Hepatic problems: Raised liver enzyme levels, liver
888:by mouth are often prescribed for the treatment of
49:. Unsourced material may be challenged and removed.
2034:"US FDA approves oral granules for scalp ringworm"
1896:Duxbury AJ, Oliver RJ, Pemberton MN (March 2000).
976:Central nervous system or neurological problems:
833:Terbinafine was discovered in 1991. It is on the
3013:
1851:: CS1 maint: bot: original URL status unknown (
1398:, is a topical nail solution of terbinafine and
457:
1939:
973:, altered stool colour, abdominal muscular pain
431:
3042:World Health Organization essential medicines
2247:
2233:
1581:(9th ed.). Elsevier. 2018. p. 694.
1229:, an enzyme that catalyzes the conversion of
1221:Like other allylamines, terbinafine inhibits
2048:
1352:can be sprinkled on a child's food to treat
1237:. In fungi, lanosterol is then converted to
212:
1767:(1). Frontline Medical Communications: 21.
1601:
2240:
2226:
1604:International Journal of Clinical Pharmacy
1442:
1440:
1438:
1436:
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1432:
1430:
1062:Sensory problems: Complete loss of taste (
631:
608:
497:
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1807:
1562:
1545:
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1523:
1201:Learn how and when to remove this message
517:
109:Learn how and when to remove this message
2182:Pharmaceutical Benefits Scheme: A-Z list
1505:
1471:
1469:
1212:
870:for superficial skin infections such as
1865:
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1217:Generic terbinafine hydrochloride pills
604:
477:
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3014:
1668:
1571:
1540:
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915:subacute cutaneous lupus erythematosus
715:C(#C\C=C\CN(C)Cc2cccc1ccccc12)C(C)(C)C
622:
315:
2221:
1832:"Lamisil (terbinafine): Side Effects"
1731:"Terbinafine - Drug Usage Statistics"
1675:. John Wiley & Sons. p. 90.
1557:. Geneva: World Health Organization.
1487:from the original on 20 December 2016
1481:electronic Medicines Compendium (eMC)
1466:
1454:from the original on 21 December 2016
1322:Despite its name it does not contain
913:Terbinafine may induce or exacerbate
577:
557:
328:
203:
171:
1711:from the original on 15 January 2024
1183:adding citations to reliable sources
1154:
414:(methyl)(naphthalen-1-ylmethyl)amine
264:
254:
47:adding citations to reliable sources
18:
849:Terbinafine is mainly effective on
537:
448:
324:(Prescription only) / GSL
13:
1409:Other names include Terbinaforce (
1319:-methyl-1-naphthalenemethanamine.
1300:, and slightly soluble in water.
1135:enzyme mutation (specifically the
1002:Immune system problems: Decreased
878:(tinea pedis), and other types of
14:
3063:
866:As a cream or powder, it is used
291:
2999:
2210:from the original on 2017-09-10.
2204:Therapeutic Goods Administration
2188:from the original on 2014-02-12.
2107:from the original on 2015-09-23.
2044:from the original on 2009-03-23.
1779:from the original on 2012-04-06.
1689:from the original on 2016-12-20.
1241:; in humans, lanosterol becomes
1159:
662:
656:
23:
2723:thymidylate synthase inhibitors
2192:
2170:
2159:from the original on 2016-11-18
2141:
2111:
2089:
2026:
1976:
1933:
1878:from the original on 2013-11-09
1859:
1824:
1783:
1748:
1723:
1170:needs additional citations for
1150:
924:
844:
740:Key:DOMXUEMWDBAQBQ-WEVVVXLNSA-N
34:needs additional citations for
2074:10.1001/jamadermatol.2015.4190
1761:The Journal of Family Practice
1693:
1662:
1638:
1595:
1579:Rang & Dale's Pharmacology
1499:
1367:
999:), liver damage, liver failure
806:. Severe side effects include
650:
304:
1:
2097:"Terbinafine brands in India"
1420:
1303:Terbinafine is produced from
1089:), skin irritation, itching,
857:and some yeasts in the genus
1954:10.1097/FTD.0000000000000215
1336:Food and Drug Administration
1279:
953:, fullness, abdominal pain,
7:
3037:Drugs developed by Novartis
1942:Therapeutic Drug Monitoring
1872:Medical Marketing and Media
1809:10.1001/archderm.137.9.1196
1448:"Terbinafine Hydrochloride"
1260:and tends to accumulate in
941:Gastrointestinal problems:
10:
3068:
1755:Markova T (January 2002).
1329:
1315:followed by reaction with
826:. It appears to result in
640:Chemical and physical data
2950:
2791:bromochlorosalicylanilide
2783:
2761:Aminoacyl tRNA synthetase
2759:
2740:
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2654:
2633:
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2264:
2206:. Australian Government.
2184:. Australian Government.
1616:10.1007/s11096-014-9969-y
1551:World Health Organization
748:
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1866:McGuire S (2008-02-05).
1506:Crawford F (July 2009).
1225:synthesis by inhibiting
1103:, increased heart rate (
1095:Stevens–Johnson syndrome
1040:Psychological problems:
358:Readily absorbed: 70–90%
1796:Archives of Dermatology
1070:) and distorted taste (
1052:, increased or unusual
841:million prescriptions.
157:Lamisil, Terbin, others
2575:Squalene monooxygenase
2412:Systemic: ketoconazole
1915:10.1038/sj.bdj.4800461
1902:British Dental Journal
1256:Terbinafine is highly
1218:
931:adverse drug reactions
929:Many side effects and
804:elevated liver enzymes
781:fungal nail infections
2603:Systemic: terbinafine
2103:. DrugsUpdate India.
1701:"The Top 300 of 2021"
1512:BMJ Clinical Evidence
1345:age four and up. The
1216:
777:pityriasis versicolor
773:antifungal medication
16:Antifungal medication
3052:1-Naphthyl compounds
2891:Whitfield's ointment
2718:Pyrimidine analogues
2534:Polyene antimycotics
1179:improve this article
1099:Other side effects:
1066:), decreased taste (
908:liver function tests
43:improve this article
2153:www.mercurydrug.com
1396:Apricus Biosciences
1363:Society and culture
1309:1,3-dichloropropene
1036:lupus erythematosus
919:lupus erythematosus
300:(Prescription only)
125:
2977:Never to phase III
2881:tribromometacresol
2851:sodium thiosulfate
2846:selenium disulfide
2742:Mitotic inhibitors
1874:. Mmm-online.com.
1382:Stada Arzneimittel
1227:squalene epoxidase
1219:
1034:reactions such as
882:(tinea corporis).
812:allergic reactions
121:
3032:Conjugated enynes
3027:CYP2D6 inhibitors
2987:
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2778:
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2656:β-glucan synthase
2650:
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2004:10.1111/jdv.16101
1682:978-3-527-32669-3
1669:Ravina E (2011).
1483:. 17 March 2016.
1305:olefin metathesis
1211:
1210:
1203:
1006:counts including
828:fungal cell death
766:
765:
694:Interactive image
590:CompTox Dashboard
332:
319:
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2125:. Archived from
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1650:www.drugbank.ca
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1187:
1176:
1164:
1153:
1145:Genetic testing
1123:), joint pain (
1077:Skin problems:
1024:agranulocytosis
935:biodistribution
927:
917:. Persons with
847:
838:
795:. It is either
757:
755:
752:(what is this?)
749:
744:
741:
736:
731:
730:
719:
716:
711:
710:
699:
674:
661:
655:
616:
592:
584:
564:
544:
524:
504:
484:
464:
447:
439:
418:
415:
410:
409:
393:Highly variable
387:
364:Protein binding
354:Bioavailability
346:Pharmacokinetic
340:
272:
226:
219:
115:
104:
98:
95:
52:
50:
40:
28:
17:
12:
11:
5:
3065:
3055:
3054:
3049:
3044:
3039:
3034:
3029:
3024:
3009:
3008:
2985:
2984:
2981:
2980:
2979:
2978:
2975:
2964:
2958:
2952:
2951:
2948:
2947:
2945:
2944:
2939:
2934:
2925:
2920:
2915:
2910:
2905:
2900:
2898:citronella oil
2894:
2893:
2888:
2883:
2878:
2873:
2868:
2863:
2858:
2853:
2848:
2843:
2841:salicylic acid
2838:
2833:
2828:
2823:
2818:
2813:
2811:crystal violet
2808:
2803:
2798:
2796:chlorophetanol
2793:
2787:
2785:
2781:
2780:
2777:
2776:
2774:
2773:
2766:
2764:
2757:
2756:
2754:
2753:
2746:
2744:
2738:
2737:
2735:
2734:
2727:
2725:
2711:
2707:
2706:
2703:
2702:
2700:
2699:
2694:
2688:
2683:
2678:
2673:
2662:
2660:
2652:
2651:
2648:
2647:
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2644:
2637:
2635:
2631:
2630:
2627:
2626:
2624:
2623:
2616:
2614:
2608:
2607:
2605:
2604:
2597:
2590:
2588:
2579:
2571:
2570:
2568:
2567:
2564:amphotericin B
2556:
2551:
2544:
2542:
2530:
2529:
2526:
2525:
2523:
2522:
2515:
2513:
2507:
2506:
2504:
2503:
2498:
2491:
2490:
2485:
2480:
2475:
2470:
2465:
2460:
2455:
2453:fosfluconazole
2450:
2443:
2442:
2437:
2432:
2425:
2423:
2417:
2416:
2414:
2413:
2409:
2408:
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2363:
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2353:
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2338:
2333:
2328:
2323:
2318:
2313:
2306:
2304:
2295:
2279:
2268:
2262:
2261:
2245:
2244:
2237:
2230:
2222:
2214:
2213:
2191:
2169:
2140:
2110:
2088:
2067:(3): 276–281.
2047:
2040:. 2007-09-28.
2025:
1998:(3): 580–588.
1975:
1948:(6): 697–698.
1932:
1908:(6): 295–296.
1888:
1858:
1823:
1782:
1747:
1722:
1692:
1681:
1661:
1637:
1610:(4): 679–683.
1594:
1587:
1570:
1539:
1498:
1465:
1425:
1424:
1422:
1419:
1418:
1417:
1414:
1411:Mankind Pharma
1407:
1391:
1388:
1385:
1378:
1374:
1369:
1366:
1364:
1361:
1331:
1328:
1281:
1278:
1209:
1208:
1167:
1165:
1158:
1152:
1149:
1129:
1128:
1113:red blood cell
1107:), hair loss (
1097:
1075:
1060:
1038:
1000:
989:
974:
926:
923:
904:hepatotoxicity
876:athlete's foot
846:
843:
808:liver problems
797:taken by mouth
793:athlete's foot
775:used to treat
764:
763:
746:
745:
743:
742:
739:
737:
734:
726:
725:
724:
721:
720:
718:
717:
714:
706:
705:
704:
701:
700:
698:
697:
689:
687:
679:
678:
672:
666:
665:
659:
653:
648:
642:
641:
637:
636:
626:
618:
617:
615:
614:
601:
599:
586:
585:
583:
582:
574:
572:
566:
565:
563:
562:
554:
552:
546:
545:
543:
542:
534:
532:
526:
525:
523:
522:
514:
512:
506:
505:
503:
502:
494:
492:
486:
485:
483:
482:
474:
472:
466:
465:
463:
462:
454:
452:
441:
440:
438:
437:
428:
426:
420:
419:
417:
416:
413:
405:
404:
403:
400:
399:
395:
394:
391:
382:
381:
376:
370:
369:
366:
360:
359:
356:
350:
349:
342:
341:
339:
338:
325:
312:
301:
287:
285:
279:
278:
274:
273:
271:
270:
247:
245:
239:
238:
229:
227:administration
221:
220:
218:
217:
199:
197:
191:
190:
183:
177:
176:
169:
159:
158:
155:
149:
148:
144:
143:
135:
134:
117:
116:
31:
29:
22:
15:
9:
6:
4:
3:
2:
3064:
3053:
3050:
3048:
3045:
3043:
3040:
3038:
3035:
3033:
3030:
3028:
3025:
3023:
3020:
3019:
3017:
3007:
2997:
2996:
2993:
2976:
2974:
2971:
2970:
2968:
2965:
2962:
2959:
2957:
2954:
2953:
2949:
2943:
2940:
2938:
2935:
2933:
2929:
2926:
2924:
2921:
2919:
2916:
2914:
2911:
2909:
2906:
2904:
2901:
2899:
2896:
2895:
2892:
2889:
2887:
2884:
2882:
2879:
2877:
2874:
2872:
2869:
2867:
2864:
2862:
2859:
2857:
2854:
2852:
2849:
2847:
2844:
2842:
2839:
2837:
2834:
2832:
2829:
2827:
2824:
2822:
2819:
2817:
2814:
2812:
2809:
2807:
2804:
2802:
2801:chlorphenesin
2799:
2797:
2794:
2792:
2789:
2788:
2786:
2782:
2772:
2768:
2767:
2765:
2762:
2758:
2752:
2748:
2747:
2745:
2743:
2739:
2733:
2729:
2728:
2726:
2724:
2719:
2715:
2712:
2710:Intracellular
2708:
2698:
2697:ibrexafungerp
2695:
2692:
2689:
2687:
2684:
2682:
2679:
2677:
2674:
2672:
2671:anidulafungin
2668:
2667:echinocandins
2664:
2663:
2661:
2657:
2653:
2643:
2639:
2638:
2636:
2632:
2622:
2618:
2617:
2615:
2613:
2609:
2601:
2598:
2596:
2592:
2591:
2589:
2587:
2583:
2580:
2576:
2572:
2565:
2560:
2557:
2555:
2552:
2550:
2546:
2545:
2543:
2540:
2535:
2531:
2521:
2517:
2516:
2514:
2512:
2508:
2502:
2499:
2497:
2493:
2492:
2489:
2486:
2484:
2481:
2479:
2478:oteseconazole
2476:
2474:
2471:
2469:
2468:isavuconazole
2466:
2464:
2461:
2459:
2456:
2454:
2451:
2449:
2445:
2444:
2441:
2438:
2436:
2433:
2431:
2430:efinaconazole
2427:
2426:
2424:
2422:
2418:
2411:
2410:
2407:
2404:
2402:
2399:
2397:
2396:sertaconazole
2394:
2392:
2389:
2387:
2384:
2382:
2379:
2377:
2374:
2372:
2369:
2367:
2364:
2362:
2359:
2357:
2354:
2352:
2351:fenticonazole
2349:
2347:
2344:
2342:
2339:
2337:
2334:
2332:
2329:
2327:
2324:
2322:
2321:chlormidazole
2319:
2317:
2314:
2312:
2308:
2307:
2305:
2303:
2299:
2296:
2293:
2287:
2283:
2280:
2276:
2272:
2269:
2263:
2258:
2254:
2250:
2243:
2238:
2236:
2231:
2229:
2224:
2223:
2220:
2209:
2205:
2201:
2195:
2187:
2183:
2179:
2178:"Terbinafine"
2173:
2158:
2154:
2150:
2144:
2129:on 2019-01-19
2128:
2124:
2120:
2114:
2106:
2102:
2098:
2092:
2084:
2080:
2075:
2070:
2066:
2062:
2058:
2051:
2043:
2039:
2035:
2029:
2021:
2017:
2013:
2009:
2005:
2001:
1997:
1993:
1986:
1979:
1971:
1967:
1963:
1959:
1955:
1951:
1947:
1943:
1936:
1929:
1925:
1921:
1916:
1911:
1907:
1903:
1899:
1892:
1877:
1873:
1869:
1862:
1854:
1848:
1833:
1827:
1819:
1815:
1810:
1805:
1801:
1797:
1793:
1786:
1778:
1774:
1770:
1766:
1762:
1758:
1751:
1736:
1732:
1726:
1710:
1706:
1702:
1696:
1688:
1684:
1678:
1674:
1673:
1665:
1651:
1647:
1646:"Terbinafine"
1641:
1633:
1629:
1625:
1621:
1617:
1613:
1609:
1605:
1598:
1590:
1588:9780702074479
1584:
1580:
1574:
1565:
1560:
1556:
1552:
1546:
1544:
1535:
1531:
1526:
1521:
1517:
1513:
1509:
1502:
1486:
1482:
1478:
1472:
1470:
1453:
1449:
1443:
1441:
1439:
1437:
1435:
1433:
1431:
1426:
1415:
1412:
1408:
1405:
1404:onychomycosis
1401:
1397:
1392:
1389:
1386:
1383:
1379:
1375:
1372:
1371:
1360:
1357:
1355:
1351:
1348:
1344:
1339:
1337:
1327:
1325:
1320:
1318:
1314:
1310:
1306:
1301:
1299:
1296:, soluble in
1295:
1291:
1287:
1286:hydrochloride
1277:
1273:
1271:
1267:
1263:
1259:
1254:
1252:
1251:cell membrane
1248:
1244:
1240:
1236:
1232:
1228:
1224:
1215:
1205:
1202:
1194:
1184:
1180:
1174:
1173:
1168:This section
1166:
1162:
1157:
1156:
1148:
1146:
1142:
1138:
1134:
1126:
1122:
1118:
1114:
1111:), decreased
1110:
1106:
1102:
1098:
1096:
1092:
1088:
1084:
1080:
1076:
1073:
1069:
1065:
1061:
1059:
1055:
1051:
1047:
1043:
1039:
1037:
1033:
1029:
1025:
1021:
1017:
1013:
1009:
1005:
1001:
998:
994:
990:
987:
983:
979:
975:
972:
968:
964:
960:
956:
952:
948:
944:
940:
939:
938:
936:
932:
922:
920:
916:
911:
909:
905:
901:
897:
896:
891:
890:onychomycosis
887:
883:
881:
877:
873:
869:
864:
862:
861:
856:
853:of the order
852:
842:
836:
831:
829:
825:
821:
817:
813:
809:
805:
800:
798:
794:
790:
786:
782:
778:
774:
770:
760:
753:
747:
738:
733:
732:
729:
722:
713:
712:
709:
702:
695:
691:
690:
688:
685:
680:
673:
671:
667:
649:
647:
643:
638:
634:
630:
627:
625:
623:ECHA InfoCard
619:
611:
607:
606:DTXSID2023640
603:
602:
600:
591:
587:
580:
576:
575:
573:
571:
567:
560:
556:
555:
553:
551:
547:
540:
536:
535:
533:
531:
527:
520:
516:
515:
513:
511:
507:
500:
496:
495:
493:
491:
487:
480:
476:
475:
473:
471:
467:
460:
456:
455:
453:
446:
442:
434:
430:
429:
427:
425:
421:
412:
411:
408:
401:
396:
392:
390:
383:
380:
377:
375:
371:
367:
365:
361:
357:
355:
351:
347:
343:
336:
326:
323:
313:
311:
302:
299:
289:
288:
286:
284:
280:
275:
267:
262:
257:
252:
249:
248:
246:
244:
240:
237:
233:
230:
228:
222:
215:
210:
201:
200:
198:
196:
192:
188:
184:
182:
178:
174:
170:
168:
164:
160:
156:
154:
150:
147:Clinical data
145:
141:
136:
132:
127:
113:
110:
102:
91:
88:
84:
81:
77:
74:
70:
67:
63:
60: –
59:
58:"Terbinafine"
55:
54:Find sources:
48:
44:
38:
37:
32:This article
30:
26:
21:
20:
2923:tea tree oil
2908:lemon myrtle
2821:ethylparaben
2751:griseofulvin
2612:Benzylamines
2599:
2501:ravuconazole
2496:albaconazole
2488:voriconazole
2483:posaconazole
2473:itraconazole
2463:hexaconazole
2381:neticonazole
2371:luliconazole
2366:ketoconazole
2356:flutrimazole
2341:eberconazole
2331:clotrimazole
2316:butoconazole
2203:
2194:
2181:
2172:
2161:. Retrieved
2152:
2143:
2131:. Retrieved
2127:the original
2123:Medex.com.bd
2122:
2113:
2100:
2091:
2064:
2060:
2050:
2037:
2028:
1995:
1991:
1978:
1945:
1941:
1935:
1927:
1905:
1901:
1891:
1880:. Retrieved
1871:
1861:
1836:. Retrieved
1826:
1799:
1795:
1785:
1764:
1760:
1750:
1738:. Retrieved
1734:
1725:
1713:. Retrieved
1704:
1695:
1671:
1664:
1653:. Retrieved
1649:
1640:
1607:
1603:
1597:
1578:
1573:
1564:10665/325771
1554:
1515:
1511:
1501:
1489:. Retrieved
1480:
1456:. Retrieved
1358:
1354:scalp fungus
1340:
1333:
1321:
1316:
1302:
1284:Terbinafine
1283:
1274:
1255:
1220:
1197:
1188:
1177:Please help
1172:verification
1169:
1151:Pharmacology
1130:
1008:pancytopenia
993:inflammation
947:constipation
928:
925:Side effects
912:
893:
884:
865:
858:
848:
845:Medical uses
832:
801:
768:
767:
756:
750:
386:Elimination
283:Legal status
277:Legal status
195:License data
105:
99:January 2023
96:
86:
79:
72:
65:
53:
41:Please help
36:verification
33:
3022:Antifungals
2963:from market
2942:pentamidine
2903:lemon grass
2861:taurolidine
2831:polynoxylin
2732:flucytosine
2676:caspofungin
2600:terbinafine
2586:Allylamines
2448:fluconazole
2440:terconazole
2435:fluconazole
2406:tioconazole
2401:sulconazole
2391:oxiconazole
2386:omoconazole
2361:isoconazole
2336:croconazole
2294:inhibitors)
2292:demethylase
2249:Antifungals
2133:January 17,
2101:Brand index
1491:17 December
1368:Brand names
1245:. However,
1243:cholesterol
1105:tachycardia
1028:neutropenia
1016:lymphopenia
967:cholestasis
955:indigestion
820:allylamines
769:Terbinafine
677: g·mol
629:100.119.605
398:Identifiers
214:terbinafine
181:MedlinePlus
153:Trade names
123:Terbinafine
3047:Fungicides
3016:Categories
2932:atovaquone
2913:orange oil
2876:tolnaftate
2871:tolciclate
2856:sulbentine
2826:haloprogin
2806:ciclopirox
2771:tavaborole
2763:inhibitors
2749:Systemic:
2730:Systemic:
2691:rezafungin
2686:micafungin
2681:cilofungin
2665:Systemic:
2659:inhibitors
2642:amorolfine
2621:butenafine
2578:inhibitors
2562:Systemic:
2539:ergosterol
2446:Systemic:
2376:miconazole
2326:climbazole
2311:bifonazole
2302:Imidazoles
2278:inhibitors
2275:Ergosterol
2163:2016-11-18
1882:2013-11-09
1838:2013-11-09
1740:14 January
1715:14 January
1655:2017-11-14
1458:8 December
1421:References
1347:antifungal
1258:lipophilic
1239:ergosterol
1235:lanosterol
1223:ergosterol
1191:March 2024
1125:arthralgia
1068:hypogeusia
1056:activity,
1042:Depression
1032:autoimmune
1012:leukopenia
971:flatulence
855:Onygenales
824:ergosterol
787:including
682:3D model (
670:Molar mass
559:CHEBI:9448
519:G7RIW8S0XP
490:ChemSpider
436:78628-80-5
433:91161-71-6
424:CAS Number
407:IUPAC name
374:Metabolism
69:newspapers
2973:Phase III
2961:Withdrawn
2918:patchouli
2866:ticlatone
2769:Topical:
2640:Topical:
2619:Topical:
2595:naftifine
2593:Topical:
2566:, hamycin
2554:natamycin
2547:Topical:
2520:abafungin
2518:Topical:
2511:Thiazoles
2494:Unknown:
2428:Topical:
2421:Triazoles
2346:econazole
2309:Topical:
2119:"Lamisil"
2020:208185915
1970:205604356
1313:neohexene
1280:Chemistry
1270:fat cells
1141:dizziness
1087:urticaria
1072:dysgeusia
997:hepatitis
982:dizziness
978:Headaches
963:gastritis
959:dyspepsia
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