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Primary peritoneal carcinoma

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The median survival of primary peritoneal carcinomas is usually shorter by 2–6 months time when compared with serous ovarian cancer. Studies show median survival varies between 11.3 and 17.8 months. One study reported 19–40 month median survival (95% CI) with a five-year survival of 26.5%.
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is also known as serous surface papillary carcinoma, primary peritoneal carcinoma, extra-ovarian serous carcinoma, primary serous papillary carcinoma, and psammomacarcinoma. It was historically classified under
103:, which include ovarian serous carcinoma, uterine serous carcinoma, fallopian tube serous carcinoma, cervical serous carcinoma, and primary peritoneal serous carcinoma really represent one entity. 392:
Alphs HH, Zahurak ML, Bristow RE, DĂ­az-Montes TP (December 2006). "Predictors of surgical outcome and survival among elderly women diagnosed with ovarian and primary peritoneal cancer".
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Jaaback KS, Ludeman L, Clayton NL, Hirschowitz L (2006). "Primary peritoneal carcinoma in a UK cancer center: comparison with advanced ovarian carcinoma over a 5-year period".
514: 311:"Phase II Trial of Bevacizumab in Persistent or Recurrent Epithelial Ovarian Cancer or Primary Peritoneal Cancer: A Gynecologic Oncology Group Study" 217: 115:
has been described. Furthermore, women with BRCA1/2 mutation have a 5% risk of developing primary peritoneal cancer even after prophylactic
745: 288: 621: 770: 507: 995: 350: 855: 343: 540: 1044: 1000: 500: 138: 607: 277: 903: 93:, or abdominal cavity. It usually affects women and is diagnosed after the age of 60; it very rarely affects men. 309:
Burger, Robert A.; Sill, Michael W.; Monk, Bradley J.; Greer, Benjamin E.; Sorosky, Joel I. (20 November 2007).
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Prognosis and treatment is the same as for the most common type of ovarian cancer, which is
885: 8: 464: 375: 368: 1065: 945: 927: 867: 696: 692: 354: 261: 236: 198: 252: 1012: 964: 955: 678: 580: 549: 409: 332: 285:"Gynecologic Cancer Treatment—Primary Peritoneal Cancer—Dana-Farber Cancer Institute" 266: 190: 186: 48: 469: 813: 687: 602: 590: 401: 322: 256: 248: 202: 182: 100: 40: 655: 638: 480: 405: 969: 932: 862: 760: 700: 643: 572: 562: 96: 86: 454: 450: 160:
Elevated albumin levels have been associated with a more favorable prognosis.
1059: 913: 595: 492: 327: 310: 112: 134:) as ovarian cancer and can also show an increased expression of HER-2/neu. 28: 875: 413: 336: 270: 194: 116: 111:
Although the precise causes are not known, a link with certain variants of
940: 893: 836: 780: 433: 1026: 150: 90: 36: 922: 845: 663: 380: 985: 53: 176: 445: 82: 391: 982: 131: 127: 81:" (CUP). Primary peritoneal cancer (PPC, or PPCa) is a 99:
and molecular biological characteristics suggest that
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Primary peritoneal carcinoma shows similar rates of
308: 237:"The cell of origin of ovarian epithelial tumours" 1057: 522: 508: 43:, which may arise from the peritoneal lining 385: 302: 228: 170: 515: 501: 58: 27: 771:Hereditary nonpolyposis colorectal cancer 326: 260: 996:Intraductal papillary mucinous neoplasm 1058: 234: 496: 215: 1045:Desmoplastic small round cell tumor 13: 746:Polymerase proofreading-associated 139:vascular endothelial growth factor 14: 1077: 608:Hereditary diffuse gastric cancer 216:Type, Cancer (21 February 2022). 106: 904:Nodular regenerative hyperplasia 187:10.1111/j.1525-1438.2006.00474.x 1006:Solid pseudopapillary neoplasm 809:Gastrointestinal stromal tumor 766:Familial adenomatous polyposis 209: 1: 814:Krukenberg tumor (metastatic) 253:10.1016/S1470-2045(08)70308-5 163: 1035:Primary peritoneal carcinoma 709:traditional serrated adenoma 315:Journal of Clinical Oncology 144: 79:carcinoma of unknown primary 22:Primary peritoneal carcinoma 7: 975:Pancreatic ductal carcinoma 406:10.1016/j.ygyno.2006.06.019 218:"Primary peritoneal cancer" 10: 1082: 991:Serous microcystic adenoma 586:Signet ring cell carcinoma 524:Digestive system neoplasia 1025: 954: 912: 899:Focal nodular hyperplasia 835: 826: 801: 779: 677: 654: 629: 620: 571: 548: 539: 530: 427: 70:Primary peritoneal cancer 47: 35: 26: 21: 1001:Mucinous cystic neoplasm 851:Hepatocellular carcinoma 705:sessile serrated adenoma 328:10.1200/JCO.2007.11.5345 1040:Peritoneal mesothelioma 789:Squamous cell carcinoma 558:Squamous cell carcinoma 235:Dubeau, L. (Dec 2008). 179:Int. J. Gynecol. Cancer 881:Hepatocellular adenoma 669:Pseudomyxoma peritonei 181:. 16 Suppl 1: 123–8. 124:tumor suppressor gene 886:Cavernous hemangioma 737:Familial adenomatous 724:Polyposis syndromes: 137:An association with 141:has been observed. 946:Gallbladder cancer 928:Cholangiocarcinoma 868:Liver angiosarcoma 802:Upper and/or lower 751:Serrated polyposis 222:Cancer Research UK 97:Histomorphological 1053: 1052: 1021: 1020: 1013:Pancreatoblastoma 965:exocrine pancreas 822: 821: 797: 796: 616: 615: 581:Gastric carcinoma 490: 489: 376:Peritoneal Cancer 321:(33): 5165–5171. 101:serous carcinomas 67: 66: 16:Medical condition 1073: 833: 832: 732:MUTYH-associated 717:Cronkhite–Canada 688:Colorectal polyp 627: 626: 603:Linitis plastica 591:Gastric lymphoma 546: 545: 537: 536: 517: 510: 503: 494: 493: 425: 424: 418: 417: 389: 383: 372: 366: 365: 363: 362: 353:. Archived from 347: 341: 340: 330: 306: 300: 299: 297: 296: 287:. Archived from 281: 275: 274: 264: 232: 226: 225: 213: 207: 206: 174: 153:ovarian cancer. 63: 62: 41:serous carcinoma 31: 19: 18: 1081: 1080: 1076: 1075: 1074: 1072: 1071: 1070: 1056: 1055: 1054: 1049: 1017: 950: 908: 818: 793: 775: 673: 650: 639:Duodenal cancer 631:Small intestine 612: 567: 526: 521: 491: 486: 485: 436: 422: 421: 390: 386: 373: 369: 360: 358: 349: 348: 344: 307: 303: 294: 292: 283: 282: 278: 233: 229: 214: 210: 175: 171: 166: 147: 109: 57: 17: 12: 11: 5: 1079: 1069: 1068: 1051: 1050: 1048: 1047: 1042: 1037: 1031: 1029: 1023: 1022: 1019: 1018: 1016: 1015: 1009: 1008: 1003: 998: 993: 978: 977: 972: 970:Adenocarcinoma 960: 958: 952: 951: 949: 948: 936: 935: 933:Klatskin tumor 930: 918: 916: 910: 909: 907: 906: 901: 889: 888: 883: 871: 870: 865: 863:Hepatoblastoma 860: 859: 858: 841: 839: 830: 824: 823: 820: 819: 817: 816: 811: 805: 803: 799: 798: 795: 794: 792: 791: 785: 783: 777: 776: 774: 773: 768: 763: 761:Adenocarcinoma 754: 753: 748: 743: 734: 729: 720: 719: 683: 681: 675: 674: 672: 671: 666: 660: 658: 652: 651: 649: 648: 647: 646: 644:Adenocarcinoma 635: 633: 624: 618: 617: 614: 613: 611: 610: 605: 600: 599: 598: 588: 583: 577: 575: 569: 568: 566: 565: 563:Adenocarcinoma 560: 554: 552: 543: 534: 528: 527: 520: 519: 512: 505: 497: 488: 487: 484: 483: 472: 457: 437: 432: 431: 429: 428:Classification 420: 419: 400:(3): 1048–53. 394:Gynecol. Oncol 384: 367: 342: 301: 276: 247:(12): 1191–7. 227: 208: 168: 167: 165: 162: 146: 143: 108: 107:Genetic causes 105: 65: 64: 51: 45: 44: 33: 32: 24: 23: 15: 9: 6: 4: 3: 2: 1078: 1067: 1064: 1063: 1061: 1046: 1043: 1041: 1038: 1036: 1033: 1032: 1030: 1028: 1024: 1014: 1011: 1010: 1007: 1004: 1002: 999: 997: 994: 992: 988: 987: 984: 980: 979: 976: 973: 971: 968: 966: 962: 961: 959: 957: 953: 947: 944: 942: 938: 937: 934: 931: 929: 926: 924: 920: 919: 917: 915: 914:Biliary tract 911: 905: 902: 900: 897: 895: 891: 890: 887: 884: 882: 879: 877: 873: 872: 869: 866: 864: 861: 857: 856:Fibrolamellar 854: 853: 852: 849: 847: 843: 842: 840: 838: 834: 831: 829: 825: 815: 812: 810: 807: 806: 804: 800: 790: 787: 786: 784: 782: 778: 772: 769: 767: 764: 762: 759: 756: 755: 752: 749: 747: 744: 742: 738: 735: 733: 730: 728: 725: 722: 721: 718: 714: 713:Peutz–Jeghers 710: 706: 702: 698: 694: 691: 689: 685: 684: 682: 680: 676: 670: 667: 665: 662: 661: 659: 657: 653: 645: 642: 641: 640: 637: 636: 634: 632: 628: 625: 623: 619: 609: 606: 604: 601: 597: 596:MALT lymphoma 594: 593: 592: 589: 587: 584: 582: 579: 578: 576: 574: 570: 564: 561: 559: 556: 555: 553: 551: 547: 544: 542: 538: 535: 533: 529: 525: 518: 513: 511: 506: 504: 499: 498: 495: 482: 478: 477: 473: 471: 467: 466: 462: 458: 456: 452: 448: 447: 443: 439: 438: 435: 430: 426: 415: 411: 407: 403: 399: 395: 388: 382: 378: 377: 371: 357:on 2010-12-24 356: 352: 346: 338: 334: 329: 324: 320: 316: 312: 305: 291:on 2008-04-29 290: 286: 280: 272: 268: 263: 258: 254: 250: 246: 242: 238: 231: 223: 219: 212: 204: 200: 196: 192: 188: 184: 180: 173: 169: 161: 158: 154: 152: 142: 140: 135: 133: 129: 126:dysfunction ( 125: 120: 118: 114: 104: 102: 98: 94: 92: 88: 84: 80: 75: 71: 61: 55: 52: 50: 46: 42: 38: 34: 30: 25: 20: 1034: 981: 963: 939: 921: 892: 874: 844: 757: 723: 697:hyperplastic 686: 679:Colon/rectum 474: 459: 440: 397: 393: 387: 374: 370: 359:. 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Retrieved 289:the original 279: 244: 241:Lancet Oncol 240: 230: 221: 211: 178: 172: 159: 155: 148: 136: 121: 117:oophorectomy 110: 95: 73: 69: 68: 941:gallbladder 894:hyperplasia 89:lining the 1027:Peritoneum 361:2008-05-07 295:2008-05-07 164:References 151:epithelial 91:peritoneum 37:Micrograph 1066:Carcinoma 986:neoplasms 923:bile duct 846:malignant 828:Accessory 758:Neoplasm: 741:Gardner's 664:Carcinoid 550:Esophagus 381:eMedicine 145:Prognosis 74:carcinoma 49:Specialty 1060:Category 956:Pancreas 727:Juvenile 701:juvenile 656:Appendix 532:GI tract 414:16876237 337:18024863 271:19038766 195:16515579 130:, BRCA, 54:Oncology 693:adenoma 573:Stomach 481:D010534 262:4176875 203:2907689 113:BRCA1/2 85:of the 983:cystic 876:benign 412:  335:  269:  259:  201:  193:  83:cancer 56:  837:Liver 622:Lower 541:Upper 455:C48.2 451:C48.1 199:S2CID 87:cells 39:of a 781:Anus 476:MeSH 465:9-CM 410:PMID 333:PMID 267:PMID 191:PMID 470:158 461:ICD 442:ICD 402:doi 398:103 379:at 323:doi 257:PMC 249:doi 183:doi 132:WT1 128:p53 72:or 1062:: 989:: 715:, 711:, 707:, 703:, 699:, 695:, 479:: 468:: 449:: 446:10 408:. 396:. 331:. 319:25 317:. 313:. 265:. 255:. 243:. 239:. 220:. 197:. 189:. 119:. 967:: 943:: 925:: 896:: 878:: 848:: 739:/ 690:: 516:e 509:t 502:v 463:- 453:- 444:- 434:D 416:. 404:: 364:. 339:. 325:: 298:. 273:. 251:: 245:9 224:. 205:. 185:: 77:"

Index


Micrograph
serous carcinoma
Specialty
Oncology
Edit this on Wikidata
carcinoma of unknown primary
cancer
cells
peritoneum
Histomorphological
serous carcinomas
BRCA1/2
oophorectomy
tumor suppressor gene
p53
WT1
vascular endothelial growth factor
epithelial
doi
10.1111/j.1525-1438.2006.00474.x
PMID
16515579
S2CID
2907689
"Primary peritoneal cancer"
"The cell of origin of ovarian epithelial tumours"
doi
10.1016/S1470-2045(08)70308-5
PMC

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