Knowledge

Oxford Vaccine Group

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Perrett, K. P.; Winter, A. P.; Kibwana, E.; Jin, C.; John, T. M.; Yu, L. M.; Borrow, R.; Curtis, N.; Pollard, A. J. (15 June 2010). "Antibody Persistence after Serogroup C Meningococcal Conjugate Immunization of United Kingdom Primary‐School Children in 1999–2000 and Response to a Booster: A Phase 4
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In 2011, the group launched the Vaccine Knowledge Project, funded by the Oxford Biomedical Research Centre. The project website aims to provide independent, evidence-based information about vaccines and infectious diseases. The NHS Choices website lists the Vaccine Knowledge website as a recommended
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Waddington, C. S.; Walker, W. T.; Oeser, C.; Reiner, A.; John, T.; Wilkins, S.; Casey, M.; Eccleston, P. E.; Allen, R. J.; Okike, I.; Ladhani, S.; Sheasby, E.; Hoschler, K.; Andrews, N.; Waight, P.; Collinson, A. C.; Heath, P. T.; Finn, A.; Faust, S. N.; Snape, M. D.; Miller, E.; Pollard, A. J. (27
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under which the financial reward would be split between partners, instead of "donat(ing) the rights to its promising coronavirus vaccine to any drugmaker" in a misguided effort "to provide medicines preventing or treating COVID-19 at a low cost or free of charge." Under the extant deal, the OVG (or
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working in collaboration with the Primary Care Unit Clinical Trials Unit (Nuffield Department of Primary Care Health Sciences) and the Jenner Institute at the University of Oxford. It is also a participant in the UK Paediatric Vaccine Group (UKPVG) and contributes to the Oxford University Hospitals
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Leroux-Roels, Isabel; Van der Wielen, Marie; Kafeja, Froukje; Vandermeulen, Corinne; Lazarus, Rajeka; Snape, Matthew D.; John, Tessa; Carre, Christophe; Nougarede, Nolwenn; Pepin, Stephanie; Leroux-Roels, Geert; Hoppenbrouwers, Karel; Pollard, Andrew J.; Van Damme, Pierre (2009). "Humoral and
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2006: a phase II trial of a new vaccine against MenB disease. This was the first time the vaccine had been used in babies. The trial results were successful and led to phase III trials and ultimately the licensing of the new vaccine,
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external link on several of its pages. The website has also been referenced in the national media in the UK, particularly during the 2014-15 US measles outbreak originating in Disneyland California. The project is a member of the
1074:"Safety and immunogenicity of AS03B adjuvanted split virion versus non-adjuvanted whole virion H1N1 influenza vaccine in UK children aged 6 months-12 years: open label, randomised, parallel group, multicentre study" 2155: 1983: 2053: 429: 1988: 1225: 787:"expert reaction to announcement that Joint Committee on Vaccination and Immunisation advises immunisation for 14 to 18 year-olds against meningococcal group W (MenW) disease" 358:
2011 onwards: Ongoing participation in an EU Childhood Life-threatening Infectious Disease Study (EUCLIDS) work package looking at genetic responses to MenC and MenB vaccines.
1360: 2581: 1138: 264:’s tertiary Paediatric Infectious Disease and Immunology Service. All OVG trials are listed on the UK Clinical Trials Gateway. OVG supports the All Trials Campaign. 764: 2085: 2003: 712: 236:. OVG has been involved with the development of the new vaccine against MenB which was licensed in Europe in 2013. The Group has also carried out research on 2130: 1449: 2170: 608: 299:
vaccine. This research showed that immunity waned over time, and formed part of the evidence leading to the changes in the UK MenC vaccine schedule in 2013.
2417: 2075: 1656: 1673: 1498: 2080: 2013: 156: 2110: 2335: 2023: 577: 271:(JCVI) in March 2014. Senior staff at OVG are periodically asked to give expert opinions on aspects of vaccines and infectious disease, especially 539: 1948: 1644: 413: 268: 1397: 2277: 2145: 1619: 2574: 2135: 2090: 2070: 448: 1323:. University of Oxford, Department of Paediatrics, Level 2, Children's Hospital, John Radcliffe, Headington, Oxford, OX3 9DU. 17 April 2020. 2252: 2160: 2095: 738: 183:, clinical research fellows, research nurses, statisticians, post-doctoral laboratory scientists, research assistants and DPhil students. 2309: 2202: 2120: 2100: 2065: 1998: 1958: 1472: 275:
disease. For example the 2015 announcement that 14- to 18-year-olds in the UK are to be vaccinated against MenW disease, and the 2012
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into new and improved vaccines for children and adults. Research by Richard Moxon into the public health impact of
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in UK children, led to the founding of OVG in 1994. Since then OVG has particularly specialised in research into
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since 2001, comprises around 75 members across a number of disciplines, including consultants in paediatrics and
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the trustees of Oxford University) will have another revenue stream with which to finance its activities.
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OVG carries out research on vaccines to improve human health. It works to enhance the understanding of
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cellular immune responses to split-virion H5N1 influenza vaccine in young and elderly adults".
316: 220: 631:"Primary Care and Vaccines Collaborative Clinical Trials Unit website. Retrieved 25 June 2015" 2474: 2424: 2227: 1927: 1802: 1752: 1747: 1717: 421: 296: 233: 229: 2529: 2491: 2444: 2257: 1968: 1917: 1683: 1628: 1018: 735:"Oxford Vaccine Group signature on the All Trials Campaign website. Retrieved 25 June 2015" 256: 252: 152: 97: 686: 348:
2009: a study comparing the effectiveness of two new vaccines against the swine flu virus
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Since 2001, OVG has enrolled over 12,500 adults and children into clinical trials in the
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2006: a study looking at the effectiveness of a new vaccine against the bird flu virus
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The OVG is funded not only by its alma mater and UK government bodies such as the
2496: 1587: 1499:"We should listen to Roald Dahl, not Jenny McCarthy, on vaccinating our children" 310:, studying children admitted to the hospital with febrile illnesses and cases of 215: 1357:"They Pledged to Donate Rights to Their COVID Vaccine, Then Sold Them to Pharma" 988: 934: 903: 841: 1523: 425: 303: 709:"Paediatric Infectious Disease and Immunology website. Retrieved 25 June 2015" 2654: 2439: 1218:"Oxford University doctors and scientists start trials for new Ebola vaccine" 1187: 1097: 889: 433: 381: 288: 272: 958: 656: 28: 2543: 1661: 1649: 1115: 237: 207: 467: 361:
2011 onwards: a series of challenge studies to test new vaccines against
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2005 onwards: collaborative projects with the paediatric department of
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Professor Andrew Pollard, OVG’s Director, was appointed Chair of the
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type b (Hib) invasive disease in the UK, and efficacy studies of the
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2010: a study of a new quadrivalent meningococcal (MenACWY) vaccine.
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2003: a study looking at the mid- to long-term effectiveness of the
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OVG is a research group within the Department of Paediatrics at the
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The group has earned attention from international funders like the
388: 191: 1553: 2434: 463: 459: 362: 342: 311: 279:(EMA) recommendation for approval of a new meningitis B vaccine. 241: 172: 70: 255:. It is a UK Clinical Research Collaboration (UKCRC) registered 168: 66: 61:
Centre for Clinical Vaccinology and Tropical Medicine (CCVTM),
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University of Oxford Department of Paediatrics website
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product led the BMGF to prod the OVG into a deal with
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2014-15: a phase 1 study into a new vaccine against
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OVG research has included: 1011: 836: 834: 1620: 1606: 1516: 1128: 926: 570:"Meningitis B tests raise hope of vaccine" 186:OVG came to public prominence in 2020 for 16:Research group of the University of Oxford 1420:"Td/IPV vaccine (3-in-1 teenage booster)" 1332: 1330: 1272: 1105: 492:In November 2021 the team were awarded a 1627: 1210: 1179: 980: 896: 831: 496:for their work on the COVID-19 vaccine. 1354: 1313: 567: 458:The probable commercial success of the 2653: 2587:Association for the Education of Women 2156:Politics & International Relations 1984:Linguistics, Philology & Phonetics 1327: 1309:. Oxford University. 23 November 2020. 715:from the original on 24 September 2015 663:from the original on 11 September 2015 580:from the original on 16 September 2015 197: 155:. It was founded in 1994 by Professor 1601: 1471:Claire Armitstead (2 February 2015). 1348: 1560:from the original on 20 October 2023 1363:from the original on 7 February 2021 999:from the original on 11 January 2009 282: 1534:from the original on 28 August 2020 1497:Jules Montague (10 February 2015). 1287:from the original on 6 January 2022 1198:from the original on 6 January 2015 989:"Meningitis B vaccine trials begin" 904:"Teen jab theory over meningitis C" 767:from the original on 20 August 2021 599:Denis Campbell (16 November 2012). 445:Bill & Melinda Gates Foundation 393:Oxford–AstraZeneca COVID-19 vaccine 13: 1400:from the original on 3 August 2015 741:from the original on 20 April 2015 14: 2672: 1576: 1452:from the original on 23 July 2015 1273:Gallagher, James (20 July 2020). 1188:"Ebola: New vaccine trial begins" 1141:from the original on 21 July 2020 914:from the original on 1 March 2009 611:from the original on 22 June 2015 2632: 2621: 2620: 1959:Asian and Middle Eastern Studies 1682: 1228:from the original on 8 June 2015 987:Fergus Walsh (20 October 2006). 397:Pfizer–BioNTech COVID-19 vaccine 387:2020 onwards: a vaccine against 27: 1546: 1438: 1412: 1386: 1375: 1355:Hancock, Jay (25 August 2020). 1299: 1266: 1240: 1186:Fergus Walsh (6 January 2015). 1153: 1129:Reg Little (18 February 2010). 1063: 952: 935:"I am testing new bird flu jab" 860: 805: 779: 753: 234:vaccines to prevent the disease 2161:Social Policy and Intervention 727: 701: 675: 649: 623: 568:Boseley, Sarah (15 May 2008). 532: 506: 430:Meningitis Research Foundation 1: 2507:Roger Bannister running track 1989:Medieval and Modern Languages 1524:"Vaccine Safety Net: members" 1131:"Never-ending war on disease" 974:10.1016/j.vaccine.2009.08.110 499: 159:, was initially based at the 2661:Clinical trial organizations 2263:Oxford University Innovation 1583:Oxford Vaccine Group website 1069:Waddington CS, et al. [http: 933:Fergus Walsh (24 May 2006). 870:Clinical Infectious Diseases 50:Research and clinical trials 7: 2592:Delegacy for Women Students 10: 2677: 2460:Rugby League Varsity Match 418:UK Research and Innovation 403: 86:Professor Andrew J Pollard 2616: 2607:Oxford University Gazette 2557: 2522: 2465:Rugby Union Varsity Match 2336:Australian rules football 2328: 2310:Hebrew and Jewish Studies 2286: 2221:Institutes and affiliates 2220: 2169: 2146:International Development 2109: 2052: 2012: 1947: 1939:Divisions and departments 1936: 1901: 1691: 1680: 1650:The Lord Patten of Barnes 1637: 1588:Vaccine Knowledge website 1554:"Pride of Britain Awards" 487: 475:Vaccine Knowledge Project 453:World Health Organization 320:type b (Hib disease) and 277:European Medicines Agency 121: 111: 103: 91: 79: 54: 46: 38: 33:Oxford Vaccine Group logo 26: 2470:University Cricket Match 1084:(may27 1): c2649–c2649. 410:Medical Research Council 327:Streptococcus pneumoniae 177:Professor Andrew Pollard 2273:Ripon College Cuddesdon 2268:Oxford University Press 1904:Permanent private halls 438:Action Medical Research 352:in children and adults. 337:in children and adults. 161:John Radcliffe Hospital 2289:Recognised independent 2238:Ineos Oxford Institute 2096:Mathematical Institute 2055:Mathematical, Physical 1338:"Oxford Vaccine Group" 494:Pride of Britain Award 317:Haemophilus influenzae 221:Haemophilus influenzae 2582:First women graduates 2475:University Golf Match 2228:Begbroke Science Park 2004:Theology and Religion 422:Public Health England 230:meningococcal disease 226:Hib conjugate vaccine 190:it created to combat 2492:Christ Church Ground 2253:Oxford-Man Institute 2131:Continuing Education 1630:University of Oxford 817:Science Media Centre 791:Science Media Centre 520:on 17 September 2016 257:clinical trials unit 253:University of Oxford 175:. The group, led by 153:University of Oxford 145:Oxford Vaccine Group 98:University of Oxford 22:Oxford Vaccine Group 2600:The Oxford Magazine 2418:Women's Lightweight 2086:Engineering Science 689:on 27 November 2015 637:on 27 November 2015 380:and Prime Minister 378:Nicola Blackwood MP 212:infectious diseases 198:Aims and background 93:Parent organization 23: 2570:fictional colleges 2502:New College Ground 2455:Polo Varsity Match 2248:Internet Institute 2233:Big Data Institute 2198:History of Science 2188:Bodleian Libraries 2172:Gardens, Libraries 1964:American Institute 1878:University College 1763:Lady Margaret Hall 1528:Vaccine Safety Net 1224:. 6 January 2015. 819:. 16 November 2012 546:on 11 January 2019 482:Vaccine Safety Net 165:Churchill Hospital 63:Churchill Hospital 21: 2648: 2647: 2450:Henley Boat Races 2445:Women's Boat Race 2413:Men's Lightweight 2216: 2215: 2057:and Life Sciences 2044:Population Health 1738:Harris Manchester 1254:. 14 January 2015 1090:10.1136/bmj.c2649 968:(49): 6918–6925. 876:(12): 1601–1610. 868:Clinical Trial". 367:paratyphoid fever 283:Research activity 141: 140: 2668: 2640: 2636: 2628: 2624: 2623: 2575:fictional people 2512:University Parks 2487:Bullingdon Green 2300:Buddhist Studies 2292: 2243:Jenner Institute 2183:Ashmolean Museum 2175: 2113: 2076:Computer Science 2058: 2016: 2015:Medical Sciences 1951: 1945: 1944: 1940: 1913:Blackfriars Hall 1905: 1695: 1686: 1631: 1622: 1615: 1608: 1599: 1598: 1570: 1569: 1567: 1565: 1550: 1544: 1543: 1541: 1539: 1520: 1514: 1513: 1511: 1509: 1494: 1488: 1487: 1485: 1483: 1468: 1462: 1461: 1459: 1457: 1442: 1436: 1435: 1433: 1431: 1416: 1410: 1409: 1407: 1405: 1390: 1384: 1379: 1373: 1372: 1370: 1368: 1352: 1346: 1345: 1334: 1325: 1324: 1317: 1311: 1310: 1303: 1297: 1296: 1294: 1292: 1270: 1264: 1263: 1261: 1259: 1244: 1238: 1237: 1235: 1233: 1214: 1208: 1207: 1205: 1203: 1183: 1177: 1176: 1174: 1172: 1163:. 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Index

Oxford Vaccine Group logo
Churchill Hospital
Oxford
England
Professor Andrew J Pollard
University of Oxford
www.ovg.ox.ac.uk
Paediatrics
University of Oxford
E. Richard Moxon
John Radcliffe Hospital
Churchill Hospital
Oxford
England
Professor Andrew Pollard
vaccinology
the vaccine
COVID-19
immunity
epidemiology
infectious diseases
clinical trials
Haemophilus influenzae
Hib conjugate vaccine
meningococcal disease
vaccines to prevent the disease
pneumococcal
typhoid
Ebola
University of Oxford

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